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Francis Barany

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Concepts & Ideas

Chemicals & Drugs

Disorders

Colorectal Neoplasms

Physiology

Living Beings

Thermus

Genes & Molecular Sequences

Devices

Oligonucleotide Array Sequence Analysis

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Network (preview)

Co-Publications
Name
19
Paty, Philip
10
Favis, Reyna
9
Soper, Steven
8
Cao, Weiguo
7
Hammer, Robert
7
Notterman, Daniel
6
Cheng, Yu-Wei
5
Shia, Jinru
5
Zirvi, Monib
5
Bacolod, Manny
4
Mayer, Alan
4
Pincas, Hanna
4
Culliford, Alfred
4
Gerry, Norman
3
Hashimoto, Masahiko

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Publications

TOP 3
Sheffer Michal; Bacolod Manny D; Zuk Or; Giardina Sarah F; Pincas Hanna; Barany Francis; Paty Philip B; Gerald William L; Notterman Daniel A; Domany Eytan
Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.
Bacolod Manny D; Schemmann Gunter S; Giardina Sarah F; Paty Philip; Notterman Daniel A; Barany Francis
Emerging paradigms in cancer genetics: some important findings from high-density single nucleotide polymorphism array studies.
Sinville Rondedrick; Coyne Jennifer; Meagher Robert J; Cheng Yu-Wei; Barany Francis; Barron Annelise; Soper Steven A
Ligase detection reaction for the analysis of point mutations using free-solution conjugate electrophoresis in a polymer microfluidic device.

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All Publications

2009: Sheffer Michal; Bacolod Manny D; Zuk Or; Giardina Sarah F; Pincas Hanna; Barany Francis; Paty Philip B; Gerald William L; Notterman Daniel A; Domany Eytan
Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):7131-6.
2009: Bacolod Manny D; Schemmann Gunter S; Giardina Sarah F; Paty Philip; Notterman Daniel A; Barany Francis
Emerging paradigms in cancer genetics: some important findings from high-density single nucleotide polymorphism array studies.
Cancer research 2009;69(3):723-7.
2008: Sinville Rondedrick; Coyne Jennifer; Meagher Robert J; Cheng Yu-Wei; Barany Francis; Barron Annelise; Soper Steven A
Ligase detection reaction for the analysis of point mutations using free-solution conjugate electrophoresis in a polymer microfluidic device.
Electrophoresis 2008;29(23):4751-60.
2008: Zeng Zhao-Shi; Weiser Martin R; Kuntz Eleanor; Chen Chin-Tung; Khan Sajid A; Forslund Ann; Nash Garrett M; Gimbel Mark; Yamaguchi Yuka; Culliford Alfred T; D'Alessio Matthew; Barany Francis; Paty Philip B
c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases.
Cancer letters 2008;265(2):258-69.
2008: Khan Sajid A; Idrees Kamran; Forslund Ann; Zeng Zhaoshi; Rosenberg Shoshana; Pincas Hanna; Barany Francis; Offit Kenneth; Laquaglia Michael P; Paty Philip B
Genetic variants in germline TP53 and MDM2 SNP309 are not associated with early onset colorectal cancer.
Journal of surgical oncology 2008;97(7):621-5.
2008: Bacolod Manny D; Schemmann Gunter S; Wang Shuang; Shattock Richard; Giardina Sarah F; Zeng Zhaoshi; Shia Jinru; Stengel Robert F; Gerry Norman; Hoh Josephine; Kirchhoff Tomas; Gold Bert; Christman Michael F; Offit Kenneth; Gerald William L; Notterman Daniel A; Ott Jurg; Paty Philip B; Barany Francis
The signatures of autozygosity among patients with colorectal cancer.
Cancer research 2008;68(8):2610-21.
2008: Forslund Ann; Zeng Zhaoshi; Qin Li-Xuan; Rosenberg Shoshana; Ndubuisi MacKevin; Pincas Hanna; Gerald William; Notterman Daniel A; Barany Francis; Paty Philip B
MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.
Molecular cancer research : MCR 2008;6(2):205-11.
2007: Hashimoto Masahiko; Barany Francis; Xu Feng; Soper Steven A
Serial processing of biological reactions using flow-through microfluidic devices: coupled PCR/LDR for the detection of low-abundant DNA point mutations.
The Analyst 2007;132(9):913-21.
2007: Gavert Nancy; Sheffer Michal; Raveh Shani; Spaderna Simone; Shtutman Michael; Brabletz Thomas; Barany Francis; Paty Phillip; Notterman Daniel; Domany Eytan; Ben-Ze'ev Avri
Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.
Cancer research 2007;67(16):7703-12.
2007: Pingle Maneesh R; Granger Kathleen; Feinberg Philip; Shatsky Rebecca; Sterling Bram; Rundell Mark; Spitzer Eric; Larone Davise; Golightly Linnie; Barany Francis
Multiplexed identification of blood-borne bacterial pathogens by use of a novel 16S rRNA gene PCR-ligase detection reaction-capillary electrophoresis assay.
Journal of clinical microbiology 2007;45(6):1927-35.
2006: Wen Yu; Giardina Sarah F; Hamming David; Greenman Jennifer; Zachariah Emmanuel; Bacolod Manny D; Liu Hao; Shia Jinru; Amenta Peter S; Barany Francis; Paty Phillip; Gerald William; Notterman Daniel
GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):5951-9.
2006: Turner Daniel J; Pingle Maneesh R; Barany Francis
Harnessing asymmetrical substrate recognition by thermostable EndoV to achieve balanced linear amplification in multiplexed SNP typing.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2006;84(2):232-42.
2006: Hashimoto Masahiko; Barany Francis; Soper Steven A
Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations.
Biosensors & bioelectronics 2006;21(10):1915-23.
2006: Tsafrir Dafna; Bacolod Manny; Selvanayagam Zachariah; Tsafrir Ilan; Shia Jinru; Zeng Zhaoshi; Liu Hao; Krier Curtis; Stengel Robert F; Barany Francis; Gerald William L; Paty Philip B; Domany Eytan; Notterman Daniel A
Relationship of gene expression and chromosomal abnormalities in colorectal cancer.
Cancer research 2006;66(4):2129-37.
2006: Cheng Yu-Wei; Shawber Carrie; Notterman Dan; Paty Philip; Barany Francis
Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay.
Genome research 2006;16(2):282-9.
2005: Soper Steven A; Hashimoto Masahiko; Situma Catherine; Murphy Michael C; McCarley Robin L; Cheng Yu-Wei; Barany Francis
Fabrication of DNA microarrays onto polymer substrates using UV modification protocols with integration into microfluidic platforms for the sensing of low-abundant DNA point mutations.
Methods (San Diego, Calif.) 2005;37(1):103-13.
2005: Hashimoto Masahiko; Hupert Mateusz L; Murphy Michael C; Soper Steven A; Cheng Yu-Wei; Barany Francis
Ligase detection reaction/hybridization assays using three-dimensional microfluidic networks for the detection of low-abundant DNA point mutations.
Analytical chemistry 2005;77(10):3243-55.
2005: Turner Daniel J; Zirvi Monib A; Barany Francis; Elenitsas Rosalie; Seykora John
Detection of the BRAF V600E mutation in melanocytic lesions using the ligase detection reaction.
Journal of cutaneous pathology 2005;32(5):334-9.
2005: Situma Catherine; Wang Yun; Hupert Mateusz; Barany Francis; McCarley Robin L; Soper Steven A
Fabrication of DNA microarrays onto poly(methyl methacrylate) with ultraviolet patterning and microfluidics for the detection of low-abundant point mutations.
Analytical biochemistry 2005;340(1):123-35.
2005: Phelan C M; Dapic V; Tice B; Favis R; Kwan E; Barany F; Manoukian S; Radice P; van der Luijt R B; van Nesselrooij B P M; Chenevix-Trench G; kConFab; Caldes T; de la Hoya M; Lindquist S; Tavtigian S V; Goldgar D; Borg A; Narod S A; Monteiro A N A
Classification of BRCA1 missense variants of unknown clinical significance.
Journal of medical genetics 2005;42(2):138-46.
2005: Favis Reyna; Gerry Norman P; Cheng Yu-Wei; Barany Francis
Applications of the universal DNA microarray in molecular medicine.
Methods in molecular medicine 2005;114():25-58.
2004: Favis Reyna; Huang Jianmin; Gerry Norman P; Culliford Alfred; Paty Philip; Soussi Thierry; Barany Francis
Harmonized microarray/mutation scanning analysis of TP53 mutations in undissected colorectal tumors.
Human mutation 2004;24(1):63-75.
2004: Thomas Gloria; Sinville Rondedrick; Sutton Shelby; Farquar Hannah; Hammer Robert P; Soper Steven A; Cheng Yu-Wei; Barany Francis
Capillary and microelectrophoretic separations of ligase detection reaction products produced from low-abundant point mutations in genomic DNA.
Electrophoresis 2004;25(10-11):1668-77.
2004: Fouquet Coralie; Antoine Martine; Tisserand Pascaline; Favis Reyna; Wislez Marie; Commo Fréderic; Rabbe Nathalie; Carette Marie France; Milleron Bernard; Barany Francis; Cadranel Jacques; Zalcman Gérard; Soussi Thierry
Rapid and sensitive p53 alteration analysis in biopsies from lung cancer patients using a functional assay and a universal oligonucleotide array: a prospective study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3479-89.
2004: Pincas Hanna; Pingle Maneesh R; Huang Jianmin; Lao Kaiqin; Paty Philip B; Friedman Alan M; Barany Francis
High sensitivity EndoV mutation scanning through real-time ligase proofreading.
Nucleic acids research 2004;32(19):e148.
2003: Overholtzer Michael; Rao Pulivarthi H; Favis Reyna; Lu Xin-Yan; Elowitz Michael B; Barany Francis; Ladanyi Marc; Gorlick Richard; Levine Arnold J
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11547-52.
2003: Nash G M; Gimbel M; Shia J; Culliford A T; Nathanson D R; Ndubuisi M; Yamaguchi Y; Zeng Z S; Barany F; Paty P B
Automated, multiplex assay for high-frequency microsatellite instability in colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(16):3105-12.
2003: Nathanson Daniel R; Culliford Alfred T; Shia Jinru; Chen Beiyun; D'Alessio Matthew; Zeng Zhao-Shi; Nash Garrett M; Gerald William; Barany Francis; Paty Philip B
HER 2/neu expression and gene amplification in colon cancer.
International journal of cancer. Journal international du cancer 2003;105(6):796-802.
2003: Wabuyele Musundi B; Farquar Hannah; Stryjewski Wieslaw; Hammer Robert P; Soper Steven A; Cheng Yu-Wei; Barany Francis
Approaching real-time molecular diagnostics: single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes.
Journal of the American Chemical Society 2003;125(23):6937-45.
2003: Wang Yun; Vaidya Bikas; Farquar Hannah D; Stryjewski Wieslaw; Hammer Robert P; McCarley Robin L; Soper Steven A; Cheng Yu-Wei; Barany Francis
Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations.
Analytical chemistry 2003;75(5):1130-40.
2002: Kirk Brian W; Feinsod Matthew; Favis Reyna; Kliman Richard M; Barany Francis
Single nucleotide polymorphism seeking long term association with complex disease.
Nucleic acids research 2002;30(15):3295-311.
2002: Huang Jianmin; Kirk Brian; Favis Reyna; Soussi Thierry; Paty Philip; Cao Weiguo; Barany Francis
An endonuclease/ligase based mutation scanning method especially suited for analysis of neoplastic tissue.
Oncogene 2002;21(12):1909-21.
2001: Dong S M; Traverso G; Johnson C; Geng L; Favis R; Boynton K; Hibi K; Goodman S N; D'Allessio M; Paty P; Hamilton S R; Sidransky D; Barany F; Levin B; Shuber A; Kinzler K W; Vogelstein B; Jen J
Detecting colorectal cancer in stool with the use of multiple genetic targets.
Journal of the National Cancer Institute 2001;93(11):858-65.
2000: Favis R; Day J P; Gerry N P; Phelan C; Narod S; Barany F
Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2.
Nature biotechnology 2000;18(5):561-4.
2000: Favis R; Barany F
Mutation detection in K-ras, BRCA1, BRCA2, and p53 using PCR/LDR and a universal DNA microarray.
Annals of the New York Academy of Sciences 2000;906():39-43.
1999: Zirvi M; Bergstrom D E; Saurage A S; Hammer R P; Barany F
Improved fidelity of thermostable ligases for detection of microsatellite repeat sequences using nucleoside analogs.
Nucleic acids research 1999;27(24):e41.
1999: Zirvi M; Nakayama T; Newman G; McCaffrey T; Paty P; Barany F
Ligase-based detection of mononucleotide repeat sequences.
Nucleic acids research 1999;27(24):e40.
1999: Gerry N P; Witowski N E; Day J; Hammer R P; Barany G; Barany F
Universal DNA microarray method for multiplex detection of low abundance point mutations.
Journal of molecular biology 1999;292(2):251-62.
1999: Khanna M; Cao W; Zirvi M; Paty P; Barany F
Ligase detection reaction for identification of low abundance mutations.
Clinical biochemistry 1999;32(4):287-90.
1999: Day J P; Hammer R P; Bergstrom D; Barany F
Nucleotide analogs and new buffers improve a generalized method to enrich for low abundance mutations.
Nucleic acids research 1999;27(8):1819-27.
1999: Day J P; Bergstrom D; Hammer R P; Barany F
Nucleotide analogs facilitate base conversion with 3' mismatch primers.
Nucleic acids research 1999;27(8):1810-8.
1999: Tong J; Cao W; Barany F
Biochemical properties of a high fidelity DNA ligase from Thermus species AK16D.
Nucleic acids research 1999;27(3):788-94.
1999: Khanna M; Park P; Zirvi M; Cao W; Picon A; Day J; Paty P; Barany F
Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors.
Oncogene 1999;18(1):27-38.
1998: Cao W; Barany F
Identification of TaqI endonuclease active site residues by Fe2+-mediated oxidative cleavage.
The Journal of biological chemistry 1998;273(49):33002-10.
1998: Cao W; Lu J; Welch S G; Williams R A; Barany F
Cloning and thermostability of TaqI endonuclease isoschizomers from Thermus species SM32 and Thermus filiformis Tok6A1.
The Biochemical journal 1998;333 ( Pt 2)():425-31.
1997: Cao W; Lu J; Barany F
Nucleotide sequences and gene organization of TaqI endonuclease isoschizomers from Thermus sp. SM32 and Thermus filiformis Tok6A1.
Gene 1997;197(1-2):205-14.
1996: Day D J; Speiser P W; Schulze E; Bettendorf M; Fitness J; Barany F; White P C
Identification of non-amplifying CYP21 genes when using PCR-based diagnosis of 21-hydroxylase deficiency in congenital adrenal hyperplasia (CAH) affected pedigrees.
Human molecular genetics 1996;5(12):2039-48.
1996: Luo J; Barany F
Identification of essential residues in Thermus thermophilus DNA ligase.
Nucleic acids research 1996;24(15):3079-85.
1996: Luo J; Bergstrom D E; Barany F
Improving the fidelity of Thermus thermophilus DNA ligase.
Nucleic acids research 1996;24(15):3071-8.
1995: Day D J; Speiser P W; White P C; Barany F
Detection of steroid 21-hydroxylase alleles using gene-specific PCR and a multiplexed ligation detection reaction.
Genomics 1995;29(1):152-62.
1995: Mayer A N; Barany F
Photoaffinity cross-linking of TaqI restriction endonuclease using an aryl azide linked to the phosphate backbone.
Gene 1995;153(1):1-8.
1995: Cao W; Mayer A N; Barany F
Stringent and relaxed specificities of TaqI endonuclease: interactions with metal cofactors and DNA sequences.
Biochemistry 1995;34(7):2276-83.
1994: Mayer A N; Barany F
Interaction of TaqI endonuclease with the phosphate backbone. Effects of stereospecific phosphate modification.
The Journal of biological chemistry 1994;269(46):29067-76.
1993: Zebala J A; Barany F
Implications for the ligase chain reaction in gastroenterology.
Journal of clinical gastroenterology 1993;17(2):171-5.
1992: Zebala J A; Choi J; Trainor G L; Barany F
DNA recognition of base analogue and chemically modified substrates by the TaqI restriction endonuclease.
The Journal of biological chemistry 1992;267(12):8106-16.
1992: Zebala J A; Choi J; Barany F
Characterization of steady state, single-turnover, and binding kinetics of the TaqI restriction endonuclease.
The Journal of biological chemistry 1992;267(12):8097-105.
1992: Barany F; Slatko B; Danzitz M; Cowburn D; Schildkraut I; Wilson G G
The corrected nucleotide sequences of the TaqI restriction and modification enzymes reveal a thirteen-codon overlap.
Gene 1992;112(1):91-5.
1992: Barany F; Zebala J
Correlation between insertion mutant activities and amino acid sequence identities of the TaqI and TthHB8 restriction endonucleases.
Gene 1992;112(1):13-20.
1992: Barany F; Danzitz M; Zebala J; Mayer A
Cloning and sequencing of genes encoding the TthHB8I restriction and modification enzymes: comparison with the isoschizomeric TaqI enzymes.
Gene 1992;112(1):3-12.
1991: Barany F; Gelfand D H
Cloning, overexpression and nucleotide sequence of a thermostable DNA ligase-encoding gene.
Gene 1991;109(1):1-11.
1991: Barany F
The ligase chain reaction in a PCR world.
PCR methods and applications 1991;1(1):5-16.
1991: Zebala J; Barany F
Mapping catalytically important regions of an enzyme using two-codon insertion mutagenesis: a case study correlating beta-lactamase mutants with the three-dimensional structure.
Gene 1991;100():51-7.
1991: Barany F
Genetic disease detection and DNA amplification using cloned thermostable ligase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(1):189-93.
1989: Glushka J; Barany F; Cowburn D
Observation of arginyl-deoxyoligonucleotide interactions in Taq I endonuclease by detection of specific 1H NMR signals from 140kD [N eta 1, N eta 2, 15N Arg]Taq I/oligomer complexes.
Biochemical and biophysical research communications 1989;164(1):88-93.
1988: Barany F
How TaqI endonuclease recognizes its cognate sequence.
Gene 1988;74(1):63-5.
1988: Barany F
Overproduction, purification and crystallization of TaqI restriction endonuclease.
Gene 1988;65(2):167-77.
1988: Barany F
The TaqI 'star' reaction: strand preferences reveal hydrogen-bond donor and acceptor sites in canonical sequence recognition.
Gene 1988;65(2):149-65.
1987: Barany F
A genetic system for isolation and characterization of TaqI restriction endonuclease mutants.
Gene 1987;56(1):13-27.

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