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Sergio Baranzini

Research Profile

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Oligonucleotide Array Sequence Analysis

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Publications

TOP 3
Pierre-Antoine Gourraud; Stephen L Hauser; Roland G Henry; Pouya Khankhanian; Paul M Matthews; Jorge R Oksenberg; Daniel Pelletier; Michael Sdika; Azadeh Beheshtian; Sergio E Baranzini
A genome-wide association study of brain lesion distribution in multiple sclerosis.
D J Pappas; Sergio E Baranzini; P A Gabatto; L Gan; P Khankhanian; D Oksenberg; J R Oksenberg
Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules.
May H Han; Peggy P Ho; Jack F V Hunt; Siddhartha Jaiswal; Christopher B Lock; Deborah H Lundgren; Cedric S Raine; Raymond A Sobel; Robert C Axtell; Sergio E Baranzini; Sara E Brownell; Eugene C Butcher; Mark Chao; Christopher S Garris; Kareem L Graham; David K Han; Irving Weissman; Joslyn I Woodard; Maria Zoudilova; Lawrence Steinman
Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice.

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All Publications

2013: Pierre-Antoine Gourraud; Stephen L Hauser; Roland G Henry; Pouya Khankhanian; Paul M Matthews; Jorge R Oksenberg; Daniel Pelletier; Michael Sdika; Azadeh Beheshtian; Sergio E Baranzini
A genome-wide association study of brain lesion distribution in multiple sclerosis.
Brain : a journal of neurology 2013;136(Pt 4):1012-24.
2012: D J Pappas; Sergio E Baranzini; P A Gabatto; L Gan; P Khankhanian; D Oksenberg; J R Oksenberg
Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules.
Neuroscience 2012;226():10-20.
2012: May H Han; Peggy P Ho; Jack F V Hunt; Siddhartha Jaiswal; Christopher B Lock; Deborah H Lundgren; Cedric S Raine; Raymond A Sobel; Robert C Axtell; Sergio E Baranzini; Sara E Brownell; Eugene C Butcher; Mark Chao; Christopher S Garris; Kareem L Graham; David K Han; Irving Weissman; Joslyn I Woodard; Maria Zoudilova; Lawrence Steinman
Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice.
The Journal of experimental medicine 2012;209(7):1325-34.
2012: Pierre-Antoine Gourraud; Hanne F Harbo; Stephen L Hauser; Sergio E Baranzini
The genetics of multiple sclerosis: an up-to-date review.
Immunological reviews 2012;248(1):87-103.
2012: Sergio E Baranzini; Dorothee Nickles
Genetics of multiple sclerosis: swimming in an ocean of data.
Current opinion in neurology 2012;25(3):239-45.
2012: Dorothee Nickles; Jorge R Oksenberg; Shan Yang; Stephen L Hauser; Pouya Khankhanian; Steve Lincoln; Lohith Madireddy; Sergio E Baranzini
In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.
BMC genomics 2012;13():477.
2011: Stephen P J Fancy; Robin J M Franklin; Emily P Harrington; Eric J Huang; Roel Nusse; Jose J Otero; Sergio E Baranzini; Charlotte C Bruce; John C Silbereis; Tracy J Yuen; Chao Zhao; David H Rowitch
Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.
Nature neuroscience 2011;14(8):1009-16.
2011: Anne M Slavotinek; Sergio E Baranzini; Denny Schanze; Cassandre Labelle-Dumais; Kieran M Short; Ryan Chao; Mani Yahyavi; Emilia K Bijlsma; Catherine Chu; Stacey Musone; Ashleigh Wheatley; Pui-Yan Kwok; Sandra Marles; Jean-Pierre Fryns; A. Murat Maga; Mohamed G Hassan; Douglas B Gould; Lohith Madireddy; Chumei Li; Timothy C Cox; Ian Smyth; Albert E Chudley; Martin Zenker
Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1.
Journal of medical genetics 2011;48(6):375-82.
2011: Sergio E Baranzini
Revealing the genetic basis of multiple sclerosis: are we there yet?
Current opinion in genetics & development 2011;21(3):317-24.
2011: Lili Wang; Sergio E Baranzini; Pouya Khankhanian; Parvin Mousavi
iCTNet: a Cytoscape plugin to produce and analyze integrative complex traits networks.
BMC bioinformatics 2011;12():380.
2011: Stephen P J Fancy; Robin J M Franklin; Sergio E Baranzini; Jonah R Chan; David H Rowitch
Myelin regeneration: a recapitulation of development?
Annual review of neuroscience 2011;34():21-43.
2011: Arash Haghikia; Moritz Perrech; Bartosz Pula; Sabrina Ruhrmann; Anja Potthoff; Norbert H Brockmeyer; Susan Goelz; Heinz Wiendl; Hans Lindå; Tjalf Ziemssen; Sergio E Baranzini; Tor-Björn Käll; Dietmar Bengel; Tomas Olsson; Ralf Gold; Andrew Chan
Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders.
PloS one 2011;6(4):e18506.
2011: Joanne H Wang; Derek Pappas; Daniel Pelletier; Chris H Polman; Sergio E Baranzini; Lori B Chibnik; Paul Iw de Bakker; Philip De Jager; David A Hafler; Stephen L Hauser; Ludwig Kappos; Paul M Matthews; Jorge R Oksenberg
Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.
Genome medicine 2011;3(1):3.
2011: Marco D Sorani; Geoffrey T Manley; J Claude Hemphill; Sergio E Baranzini
Dynamic, multi-level network models of clinical trials.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2011;():38-49.
2010: Sergio E Baranzini; Radhika Srinivasan; Pouya Khankhanian; Darin T Okuda; Sarah J Nelson; Paul Matthews; Stephen L Hauser; Jorge R Oksenberg; Daniel Pelletier
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis.
Brain : a journal of neurology 2010;133(9):2603-11.
2010: Jorge R Oksenberg; Sergio E Baranzini
Multiple sclerosis genetics--is the glass half full, or half empty?
Nature reviews. Neurology 2010;6(8):429-37.
2010: Sergio E Baranzini; Joann Mudge; Jennifer C Van Velkinburgh; Pouya Khankhanian; Irina Khrebtukova; Neil A Miller; Lu Zhang; Andrew D Farmer; Callum J Bell; Ryan W Kim; Gregory D May; Jimmy E Woodward; Stacy J Caillier; Joseph P McElroy; Refujia Gomez; Marcelo J Pando; Leonda E Clendenen; Elena E Ganusova; Faye D Schilkey; Thiruvarangan Ramaraj; OA Khan; Jim J Huntley; Shujun Luo; Pui-Yan Kwok; Thomas D Wu; Gary P Schroth; Jorge R Oksenberg; Stephen L Hauser; Stephen Kingsmore
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.
Nature 2010;464(7293):1351-6.
2010: Pouya Khankhanian; Pierre-Antoine Gourraud; Stacy J Caillier; Adam Santaniello; Stephen L Hauser; Sergio E Baranzini; Jorge R Oksenberg
Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset.
BMC genomics 2010;11():626.
2009: Sergio E Baranzini
The genetics of autoimmune diseases: a networked perspective.
Current opinion in immunology 2009;21(6):596-605.
2009: D J Pappas; G Coppola; P A Gabatto; Fen-Biao Gao; Daniel Geschwind; Jorge R Oksenberg; Sergio E Baranzini
Longitudinal system-based analysis of transcriptional responses to type I interferons.
Physiological genomics 2009;38(3):362-71.
2009: Stephen P J Fancy; Sergio E Baranzini; Chao Zhao; Dong-In Yuk; Karen-Amanda Irvine; Sovann Kaing; Nader Sanai; Robin J M Franklin; David H Rowitch
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.
Genes & development 2009;23(13):1571-85.
2009: Sergio E Baranzini; Nicholas W Galwey; Joanne Wang; Pouya Khankhanian; Raija Lindberg; Daniel Pelletier; Wen Wu; Bernard M J Uitdehaag; Ludwig Kappos; Chris H Polman; Paul Matthews; Stephen L Hauser; Rachel A Gibson; Jorge R Oksenberg; Michael R Barnes
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis.
Human molecular genetics 2009;18(11):2078-90.
2009: D T Okuda; E M Mowry; A Beheshtian; Emmanuelle Waubant; Sergio E Baranzini; Douglas Goodin; Stephen L Hauser; D Pelletier
Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.
Neurology 2009;72(9):800-5.
2009: Pablo Villoslada; Lawrence Steinman; Sergio E Baranzini
Systems biology and its application to the understanding of neurological diseases.
Annals of neurology 2009;65(2):124-39.
2009: Manuel Comabella; Jordi Río; Carmen Espejo; Mamen Ruiz de Villa; Hammad Al-Zayat; Carlos Nos; Florian Deisenhammer; Sergio E Baranzini; Lara Nonell; Cristina López; Eva Julià; Jorge R Oksenberg; Xavier Montalban
Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2009;130(2):145-50.
2009: David Otaegui; Sergio E Baranzini; Rubén Armañanzas; Borja Calvo; Maider Muñoz-Culla; Puya Khankhanian; Iñaki Inza; Jose A Lozano; Tamara Castillo-Triviño; Ana Asensio; Javier Olaskoaga; Adolfo López de Munain
Differential micro RNA expression in PBMC from multiple sclerosis patients.
PloS one 2009;4(7):e6309.
2009: D T Okuda; Radhika Srinivasan; Jorge R Oksenberg; Douglas Goodin; Sergio E Baranzini; A Beheshtian; Emmanuelle Waubant; Scott S Zamvil; David Leppert; P Qualley; Robin R Lincoln; R Gomez; Stacy J Caillier; M George; Juehu Wang; Sarah J Nelson; Bruce A C Cree; Stephen L Hauser; Daniel Pelletier
Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures.
Brain : a journal of neurology 2009;132(Pt 1):250-9.
2008: Stacy J Caillier; Farren Briggs; Bruce A C Cree; Sergio E Baranzini; Marcelo Fernandez-Viña; Patricia P Ramsay; OA Khan; Walter III Royal; Stephen L Hauser; Lisa F Barcellos; Jorge R Oksenberg
Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(8):5473-80.
2008: Jean-Christophe Corvol; Daniel Pelletier; Roland G Henry; Stacy J Caillier; Joanne Wang; Derek Pappas; Simona Casazza; Darin T Okuda; Stephen L Hauser; Jorge R Oksenberg; Sergio E Baranzini
Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11839-44.
2008: Jorge R Oksenberg; Sergio E Baranzini; Stephen Sawcer; Stephen L Hauser
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis.
Nature reviews. Genetics 2008;9(7):516-26.
2008: Robert Goertsches; Sergio E Baranzini; Carlos Morcillo; Carlos Nos; Montse Camiña; Jorge R Oksenberg; Xavier Montalban; Manuel Comabella
Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(3):412-4.
2008: Esther Byun; Stacy J Caillier; Xavier Montalban; Pablo Villoslada; Oscar Fernández; David Brassat; Manuel Comabella; Joanne Wang; Lisa F Barcellos; Sergio E Baranzini; Jorge R Oksenberg
Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.
Archives of neurology 2008;65(3):337-44.
2008: May H Han; Sun-Il Hwang; Dolly B Roy; Deborah H Lundgren; Jordan V Price; Shalina S Ousman; Guy Haskin Fernald; Bruce Gerlitz; William H Robinson; Sergio E Baranzini; Brian W Grinnell; Cedric S Raine; Raymond A Sobel; David K Han; Lawrence Steinman
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.
Nature 2008;451(7182):1076-81.
2007: David Otaegui; Sara Mostafavi; Claude C A Bernard; Adolfo Lopez de Munain; Parvin Mousavi; Jorge R Oksenberg; Sergio E Baranzini
Increased transcriptional activity of milk-related genes following the active phase of experimental autoimmune encephalomyelitis and multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):4074-82.
2007: Uma Sriram; Michael Wong; Stacy J Caillier; Frederick Hecht; Mary K Elkins; Jay A Levy; Jorge R Oksenberg; Sergio E Baranzini
Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy.
AIDS research and human retroviruses 2007;23(5):741-7.
2007: Guy Haskin Fernald; Simon Knott; Andrew R Pachner; Stacy J Caillier; Kavitha Narayan; Jorge R Oksenberg; Parvin Mousavi; Sergio E Baranzini
Genome-wide network analysis reveals the global properties of IFN-beta immediate transcriptional effects in humans.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(8):5076-85.
2007: Shannon E Dunn; Shalina S Ousman; Raymond A Sobel; Luis Zuniga; Sergio E Baranzini; Sawsan Youssef; Andrea Crowell; John Loh; Jorge R Oksenberg; Lawrence Steinman
Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.
The Journal of experimental medicine 2007;204(2):321-30.
2007: Enrico Pedemonte; Federica Benvenuto; Simona Casazza; Gianluigi Mancardi; Jorge R Oksenberg; Antonio Uccelli; Sergio E Baranzini
The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse.
BMC genomics 2007;8():65.
2006: Sergio E Baranzini
Systems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis.
Autoimmunity 2006;39(8):651-62.
2006: Lisa F Barcellos; Stephen Sawcer; Patricia P Ramsay; Sergio E Baranzini; Glenys Thomson; Farren Briggs; Bruce C A Cree; Ann B Begovich; Pablo Villoslada; Xavier Montalban; Antonio Uccelli; Giovanni Savettieri; Robin R Lincoln; Carolyn DeLoa; Jonathan L Haines; Margaret Pericak-Vance; Alastair Compston; Stephen L Hauser; Jorge R Oksenberg
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.
Human molecular genetics 2006;15(18):2813-24.
2006: Sara Mostafavi; Sergio E Baranzini; Jorge Oksernberg; Parvin Mousavi
Predictive modeling of therapy response in multiple sclerosis using gene expression data.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2006;1():5519-22.
2005: Guy Haskin Fernald; Ru-Fang Yeh; Stephen L Hauser; Jorge R Oksenberg; Sergio E Baranzini
Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis.
Journal of neuroimmunology 2005;167(1-2):157-69.
2005: Sergio E Baranzini; Claude C A Bernard; Jorge R Oksenberg
Modular transcriptional activity characterizes the initiation and progression of autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7412-22.
2005: Sergio E Baranzini; Jorge R Oksenberg
Genomics and new targets for multiple sclerosis.
Pharmacogenomics 2005;6(2):151-61.
2005: Mary K Elkins; E Vittinghoff; Sergio E Baranzini; Frederick Hecht; Uma Sriram; M P Busch; J A Levy; Jorge R Oksenberg
Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection.
Genes and immunity 2005;6(1):66-9.
2005: Sergio E Baranzini; Parvin Mousavi; Jordi Rio; Stacy J Caillier; Althea Stillman; Pablo Villoslada; Matthew M Wyatt; Manuel Comabella; Larry D Greller; Roland Somogyi; Xavier Montalban; Jorge R Oksenberg
Transcription-based prediction of response to IFNbeta using supervised computational methods.
PLoS biology 2005;3(1):e2.
2004: Sergio E Baranzini
Gene expression profiling in neurological disorders: toward a systems-level understanding of the brain.
Neuromolecular medicine 2004;6(1):31-51.
2004: Jorge R Oksenberg; Lisa F Barcellos; Bruce A C Cree; Sergio E Baranzini; Teodorica L Bugawan; OA Khan; Robin R Lincoln; Amy Swerdlin; Emmanuel Mignot; Ling Lin; Douglas Goodin; Henry A Erlich; Silke Schmidt; Glenys Thomson; David E Reich; Margaret Pericak-Vance; Jonathan L Haines; Stephen L Hauser
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans.
American journal of human genetics 2004;74(1):160-7.
2003: Jarkko Huuskonen; Monika Abedin; Meeta Vishnu; Clive R Pullinger; Sergio E Baranzini; John P Kane; Phoebe E Fielding; Christopher J Fielding
Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts.
Biochemical and biophysical research communications 2003;306(2):463-8.
2003: Stacy J Caillier; Lisa F Barcellos; Sergio E Baranzini; Amy Swerdlin; Robin R Lincoln; Lawrence Steinman; Eden R Martin; Jonathan L Haines; Margaret Pericak-Vance; Stephen L Hauser; Jorge R Oksenberg
Osteopontin polymorphisms and disease course in multiple sclerosis.
Genes and immunity 2003;4(4):312-5.
2003: Uma Sriram; Lisa F Barcellos; Pablo Villoslada; Jordi Rio; Sergio E Baranzini; Stacy J Caillier; Althea Stillman; Stephen L Hauser; Xavier Montalban; Jorge R Oksenberg
Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis.
Genes and immunity 2003;4(2):147-52.
2002: Sergio E Baranzini; Stephen L Hauser
Large-scale gene-expression studies and the challenge of multiple sclerosis.
Genome biology 2002;3(10):reviews1027.
2002: Pablo Villoslada; Lisa F Barcellos; Jordi Rio; Ann B Begovich; Mar Tintore; Jaume Sastre-Garriga; Sergio E Baranzini; Pilar Casquero; Stephen L Hauser; Xavier Montalban; Jorge R Oksenberg
The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta.
Journal of neuroimmunology 2002;130(1-2):194-201.
2002: Sergio E Baranzini; Kenneth D Laxer; Andrew Bollen; Jorge R Oksenberg
Gene expression analysis reveals altered brain transcription of glutamate receptors and inflammatory genes in a patient with chronic focal (Rasmussen's) encephalitis.
Journal of neuroimmunology 2002;128(1-2):9-15.
2002: Sergio E Baranzini; Kenneth D Laxer; R Saketkhoo; Mary K Elkins; Jack M Parent; R Mantegazza; Jorge R Oksenberg
Analysis of antibody gene rearrangement, usage, and specificity in chronic focal encephalitis.
Neurology 2002;58(5):709-16.
2002: Sergio E Baranzini; Jorge R Oksenberg; Stephen L Hauser
New insights into the genetics of multiple sclerosis.
Journal of rehabilitation research and development 2002;39(2):201-9.
2001: Dorothee Chabas; Sergio E Baranzini; Dennis Mitchell; Claude C A Bernard; S R Rittling; D T Denhardt; Raymond A Sobel; Christopher Lock; marcela karpuj; Rosetta Pedotti; R Heller; Jorge R Oksenberg; Lawrence Steinman
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease.
Science (New York, N.Y.) 2001;294(5547):1731-5.
2001: Jorge R Oksenberg; Sergio E Baranzini; Lisa F Barcellos; Stephen L Hauser
Multiple sclerosis: genomic rewards.
Journal of neuroimmunology 2001;113(2):171-84.
2000: Sergio E Baranzini; C Elfstrom; S Y Chang; C Butunoi; R Murray; R Higuchi; Jorge R Oksenberg
Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6576-82.
1999: Sergio E Baranzini; MC Jeong; C Butunoi; R S Murray; Claude C A Bernard; Jorge R Oksenberg
B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):5133-44.