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Won-Jae Lee

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Kyung-Ah Lee; Ji-Hwan Ryu; Hyejin You; Eun-Mi Ha; Boram Kim; Eun-Kyoung Kim; Min-Ji Kim; Sung-Hee Kim; Youngjoo Kwon; Won-Jae Lee
Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila.
Hyuck-Jin Nam; Hyejin You; In-Hwan Jang; Kyung-Ah Lee; Won-Jae Lee
Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila.
Xiaoqiang Chen; Kyung-Ah Lee; Eun-Mi Ha; Kyung Mi Lee; You Yeong Seo; Han Kyoung Choi; Ha Na Kim; Min Jung Kim; Chun-Seok Cho; Soo Young Lee; Won-Jae Lee; Juyoung Yoon
A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production.

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All Publications

2013: Kyung-Ah Lee; Ji-Hwan Ryu; Hyejin You; Eun-Mi Ha; Boram Kim; Eun-Kyoung Kim; Min-Ji Kim; Sung-Hee Kim; Youngjoo Kwon; Won-Jae Lee
Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila.
Cell 2013;153(4):797-811.
2012: Hyuck-Jin Nam; Hyejin You; In-Hwan Jang; Kyung-Ah Lee; Won-Jae Lee
Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila.
The EMBO journal 2012;31(5):1253-65.
2011: Xiaoqiang Chen; Kyung-Ah Lee; Eun-Mi Ha; Kyung Mi Lee; You Yeong Seo; Han Kyoung Choi; Ha Na Kim; Min Jung Kim; Chun-Seok Cho; Soo Young Lee; Won-Jae Lee; Juyoung Yoon
A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production.
Chemical communications (Cambridge, England) 2011;47(15):4373-5.
2010: Yun Soo Bae; Myoung Kwon Choi; Won-Jae Lee
Dual oxidase in mucosal immunity and host-microbe homeostasis.
Trends in immunology 2010;31(7):278-87.
2010: Ji-Hwan Ryu; Eun-Mi Ha; Won-Jae Lee
Innate immunity and gut-microbe mutualism in Drosophila.
Developmental and comparative immunology 2010;34(4):369-76.
2009: Won-Jae Lee
Bacterial-modulated host immunity and stem cell activation for gut homeostasis.
Genes & development 2009;23(19):2260-5.
2009: Eun-Mi Ha; Kyung-Ah Lee; You Yeong Seo; Sung-Hee Kim; Jae-Hong Lim; Byung-Ha Oh; Jaesang Kim; Won-Jae Lee
Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut.
Nature immunology 2009;10(9):949-57.
2009: Eun-Mi Ha; Kyung-Ah Lee; Seon Hwa Park; Sung-Hee Kim; Hyuck-Jin Nam; Hyo young LEE; Dongmin Kang; Won-Jae Lee
Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity.
Developmental cell 2009;16(3):386-97.
2008: Hyuck-Jin Nam; In-Hwan Jang; Tsunaki Asano; Won-Jae Lee
Involvement of pro-phenoloxidase 3 in lamellocyte-mediated spontaneous melanization in Drosophila.
Molecules and cells 2008;26(6):606-10.
2008: In-Hwan Jang; Hyuck-Jin Nam; Won-Jae Lee
CLIP-domain serine proteases in Drosophila innate immunity.
BMB reports 2008;41(2):102-7.
2008: Ji-Hwan Ryu; Sung-Hee Kim; Hyo young LEE; Jin Young Bai; young-do nam; Jin-Woo Bae; Dong Gun Lee; Seung Chul Shin; Eun-Mi Ha; Won-Jae Lee
Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila.
Science (New York, N.Y.) 2008;319(5864):777-82.
2006: Ji-Hwan Ryu; Eun-Mi Ha; Chun-Taek Oh; Jae-Hong Seol; Paul T Brey; Ingnyol Jin; Dong Gun Lee; Jaesang Kim; Daekee Lee; Won-Jae Lee
An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity.
The EMBO journal 2006;25(15):3693-701.
2006: Zakaria Kambris; Sylvain Brun; In-Hwan Jang; Hyuck-Jin Nam; Yves Romeo; Kuniaki Takahashi; Won-Jae Lee; Ryu Ueda; Bruno Lemaitre
Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation.
Current biology : CB 2006;16(8):808-13.
2006: In-Hwan Jang; Naoyuki CHOSA; Sung-Hee Kim; Hyuck-Jin Nam; Bruno Lemaitre; Masanori Ochiai; Zakaria Kambris; Sylvain Brun; Carl Hashimoto; Masaaki Ashida; Paul T Brey; Won-Jae Lee
A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity.
Developmental cell 2006;10(1):45-55.
2005: Eun-Mi Ha; Chun-Taek Oh; Yun Soo Bae; Won-Jae Lee
A direct role for dual oxidase in Drosophila gut immunity.
Science (New York, N.Y.) 2005;310(5749):847-50.
2005: Eun-Mi Ha; Chun-Taek Oh; Ji-Hwan Ryu; Yun-Soo Bae; Sang-Won Kang; In-Hwan Jang; Paul T Brey; Won-Jae Lee
An antioxidant system required for host protection against gut infection in Drosophila.
Developmental cell 2005;8(1):125-32.
2004: S-H Han; Ji-Hwan Ryu; Chun-Taek Oh; Ki-Bum Nam; Hyuck-Jin Nam; In-Hwan Jang; Paul T Brey; Won-Jae Lee
The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia.
Insect molecular biology 2004;13(3):323-7.
2004: Sang-Pyo Kim; Jong-Wook Park; Sung-Hee Lee; Jun Hee Lim; Byeong-Churl Jang; Sang-Han Lee; In-Hwan Jang; Jean-Noel Freund; Seong-Il Suh; Kyo-Cheol Mun; Dae-Kyu Song; Eun-Mi Ha; Won-Jae Lee; Taeg Kyu Kwon
Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer.
Biochemical and biophysical research communications 2004;315(1):93-9.
2004: Ji-Hwan Ryu; Ki-Bum Nam; Chun-Taek Oh; Hyuck-Jin Nam; Sung-Hee Kim; Joo-Heon Yoon; Je-Kyeong Seong; Mi-Ae Yoo; In-Hwan Jang; Paul T Brey; Won-Jae Lee
The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia.
Molecular and cellular biology 2004;24(1):172-85.