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Jae Yoon Leem

Research Profile

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Haipeng Cheng; Kulandaivelu S Vetrivel; Renaldo C Drisdel; Xavier Meckler; Ping Gong; Jae Yoon Leem; Tong Li; Meghan Carter; Ying Chen; Phuong Nguyen; Takeshi Iwatsubo; Taisuke Tomita; Philip C Wong; William N Green; Maria Z Kounnas; Gopal Thinakaran
S-palmitoylation of gamma-secretase subunits nicastrin and APH-1.
Dongming Cai; Jae Yoon Leem; Jeffrey P Greenfield; Pei Wang; Benny S Kim; Runsheng Wang; Kryslaine O Lopes; Seong-Hun Kim; Hui Zheng; Paul Greengard; Sangram S Sisodia; Gopal Thinakaran; Huaxi Xu
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
Gopal Thinakaran; James W Bowen; Daisuke Ito; Jae Yoon Leem; Margaret L Veselits; Naoyuki Sato
Investigation of unfolded-protein response in cells expressing familial Alzheimer's disease-linked presenilin variants.

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2009: Haipeng Cheng; Kulandaivelu S Vetrivel; Renaldo C Drisdel; Xavier Meckler; Ping Gong; Jae Yoon Leem; Tong Li; Meghan Carter; Ying Chen; Phuong Nguyen; Takeshi Iwatsubo; Taisuke Tomita; Philip C Wong; William N Green; Maria Z Kounnas; Gopal Thinakaran
S-palmitoylation of gamma-secretase subunits nicastrin and APH-1.
The Journal of biological chemistry 2009;284(3):1373-84.
2003: Dongming Cai; Jae Yoon Leem; Jeffrey P Greenfield; Pei Wang; Benny S Kim; Runsheng Wang; Kryslaine O Lopes; Seong-Hun Kim; Hui Zheng; Paul Greengard; Sangram S Sisodia; Gopal Thinakaran; Huaxi Xu
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.
The Journal of biological chemistry 2003;278(5):3446-54.
2003: Gopal Thinakaran; James W Bowen; Daisuke Ito; Jae Yoon Leem; Margaret L Veselits; Naoyuki Sato
Investigation of unfolded-protein response in cells expressing familial Alzheimer's disease-linked presenilin variants.
Methods in molecular biology (Clifton, N.J.) 2003;232():203-16.
2002: Jae Yoon Leem; Carlos A Saura; Claus U Pietrzik; John C Christianson; Christian P Wanamaker; LaShaunda T King; Margaret L Veselits; Taisuke Tomita; Laura Gasparini; Takeshi Iwatsubo; Huaxi Xu; William N Green; Edward H Koo; Gopal Thinakaran
A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface.
Neurobiology of disease 2002;11(1):64-82.
2002: Jae Yoon Leem; Shrijay Vijayan; Ping Han; Dongming Cai; Michael Machura; Kryslaine O Lopes; Margaret L Veselits; Huaxi Xu; Gopal Thinakaran
Presenilin 1 is required for maturation and cell surface accumulation of nicastrin.
The Journal of biological chemistry 2002;277(21):19236-40.
2001: Seong-Hun Kim; Jae Yoon Leem; James J Lah; Hilda H Slunt; Allan Levey; Gopal Thinakaran; Sangram S Sisodia
Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
The Journal of biological chemistry 2001;276(46):43343-50.
2000: Carlos A Saura; Taisuke Tomita; Salvador Soriano; M Takahashi; Jae Yoon Leem; T Honda; Edward H Koo; Takeshi Iwatsubo; Gopal Thinakaran
The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.
The Journal of biological chemistry 2000;275(22):17136-42.