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François Lefèvre

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Nathalie Daniel-Carlier; Louis-Marie Houdebine; François Lefèvre; Mathieu Leroux-Coyau; Bruno Passet; Ashraf Sawafta; Dominique Thépot; Geneviève Jolivet
Viral infection resistance conferred on mice by siRNA transgenesis.
Daniela Santos Pontes; Juliana Franco Almeida; Vasco Azevedo; Sébastien Blugeon; Claire Cherbuy; Alejandra de Moreno de Leblanc; Silvina Del Carmen; Silvia Innocentin; Philippe Langella; Jean-Guy Leblanc; François Lefèvre; Anderson Miyoshi; Jean-Marc Chatel
Production of Fibronectin Binding Protein A at the surface of Lactococcus lactis increases plasmid transfer in vitro and in vivo.
Laurence Flori; Yu Gao; Joëlle Laffitte; Denis Laloë; François Lefèvre; Gaëtan Lemonnier; Jean-Jacques Leplat; Marie-José Mercat; Isabelle P Oswald; Philippe Pinton; Jean-Pierre Bidanel; Marcel Bouffaud; Anne-Marie Cossalter; Christiane de Vaureix; Angélique Teillaud; Claire Rogel-Gaillard
Immunity traits in pigs: substantial genetic variation and limited covariation.

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All Publications

2013: Nathalie Daniel-Carlier; Louis-Marie Houdebine; François Lefèvre; Mathieu Leroux-Coyau; Bruno Passet; Ashraf Sawafta; Dominique Thépot; Geneviève Jolivet
Viral infection resistance conferred on mice by siRNA transgenesis.
Transgenic research 2013;22(3):489-500.
2012: Daniela Santos Pontes; Juliana Franco Almeida; Vasco Azevedo; Sébastien Blugeon; Claire Cherbuy; Alejandra de Moreno de Leblanc; Silvina Del Carmen; Silvia Innocentin; Philippe Langella; Jean-Guy Leblanc; François Lefèvre; Anderson Miyoshi; Jean-Marc Chatel
Production of Fibronectin Binding Protein A at the surface of Lactococcus lactis increases plasmid transfer in vitro and in vivo.
PloS one 2012;7(9):e44892.
2011: Laurence Flori; Yu Gao; Joëlle Laffitte; Denis Laloë; François Lefèvre; Gaëtan Lemonnier; Jean-Jacques Leplat; Marie-José Mercat; Isabelle P Oswald; Philippe Pinton; Jean-Pierre Bidanel; Marcel Bouffaud; Anne-Marie Cossalter; Christiane de Vaureix; Angélique Teillaud; Claire Rogel-Gaillard
Immunity traits in pigs: substantial genetic variation and limited covariation.
PloS one 2011;6(7):e22717.
2010: Laurie Watterlot; Tatiana Rochat; Harry Sokol; Claire Cherbuy; Ismael Bouloufa; François Lefèvre; Jean-Jacques Gratadoux; Edith Honvo-Hueto; Stefan Chilmonczyk; Sébastien Blugeon; Gérard Corthier; Philippe Langella; Luis G Bermúdez-Humarán
Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice.
International journal of food microbiology 2010;144(1):35-41.
2009: Silvia Innocentin; Valéria Dellaretti Guimarães; Anderson Miyoshi; Vasco Azevedo; Philippe Langella; Jean-Marc Chatel; François Lefèvre
Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein A or Listeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells.
Applied and environmental microbiology 2009;75(14):4870-8.
2009: Marielle Cochet; Daniel Vaiman; François Lefèvre
Novel interferon delta genes in mammals: cloning of one gene from the sheep, two genes expressed by the horse conceptus and discovery of related sequences in several taxa by genomic database screening.
Gene 2009;433(1-2):88-99.
2008: Luis G Bermúdez-Humarán; Naima Cortes-Perez; Sandrine Ah-Leung; François Lefèvre; Guang Yang; Qingfeng Pang; Changyi Wu; Yinming Zeng; Karine Adel-Patient; Philippe Langella
Current prophylactic and therapeutic uses of a recombinant Lactococcus lactis strain secreting biologically active interleukin-12.
Journal of molecular microbiology and biotechnology 2008;14(1-3):80-9.
2007: Naima Cortes-Perez; François Lefèvre; Gérard Corthier; Karine Adel-Patient; Philippe Langella; Luis G Bermúdez-Humarán
Influence of the route of immunization and the nature of the bacterial vector on immunogenicity of mucosal vaccines based on lactic acid bacteria.
Vaccine 2007;25(36):6581-8.
2006: Valéria Dellaretti Guimarães; Silvia Innocentin; François Lefèvre; Vasco Azevedo; Jean-Michel Wal; Philippe Langella; Jean-Marc Chatel
Use of native lactococci as vehicles for delivery of DNA into mammalian epithelial cells.
Applied and environmental microbiology 2006;72(11):7091-7.
2006: Béatrice Riteau; Christiane de Vaureix; François Lefèvre
Trypsin increases pseudorabies virus production through activation of the ERK signalling pathway.
The Journal of general virology 2006;87(Pt 5):1109-12.
2005: Luis G Bermúdez-Humarán; Naima Cortes-Perez; François Lefèvre; Valéria Dellaretti Guimarães; Sylvie Rabot; Juan M Alcocer-Gonzalez; Jean-Jacques Gratadoux; Cristina Rodriguez-Padilla; Reyes S Tamez-Guerra; Gérard Corthier; Alexandra Gruss; Philippe Langella
A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7297-302.
2005: Valéria Dellaretti Guimarães; Jane Eyre Gabriel; François Lefèvre; Didier Cabanes; Alexandra Gruss; Pascale Cossart; Vasco Azevedo; Philippe Langella
Internalin-expressing Lactococcus lactis is able to invade small intestine of guinea pigs and deliver DNA into mammalian epithelial cells.
Microbes and infection / Institut Pasteur 2005;7(5-6):836-44.
2005: Daniela Tudor; Catherine Dubuquoy; Valérie Gaboriau; François Lefèvre; Bernard Charley; Sabine Riffault
TLR9 pathway is involved in adjuvant effects of plasmid DNA-based vaccines.
Vaccine 2005;23(10):1258-64.
2004: Paulo Marcelo; François Lefèvre
IFN-gamma gene expression in epithelial trophectoderm cells is linked to downregulation of the p44/p42 MAP kinase pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004;24(1):29-36.
2003: Paulo Marcelo; Marielle Bernoin; François Lefèvre
Atypical mechanisms regulate the PMA-induced expression of IFN-gamma in a porcine trophectoderm cell line.
Veterinary immunology and immunopathology 2003;92(3-4):163-72.
2002: Paulo Marcelo; François Lefèvre
Induction of the IFN-gamma gene and protein is linked to the establishment of cell polarity in a porcine epithelial cell line.
Experimental cell research 2002;280(1):33-44.
2002: Avrelija Cencic; Céline Henry; François Lefèvre; Jean-Claude Huet; Srecko Koren; Claude La Bonnardière
The porcine trophoblastic interferon-gamma, secreted by a polarized epithelium, has specific structural and biochemical properties.
European journal of biochemistry / FEBS 2002;269(11):2772-81.
2001: D Tudor; Sabine Riffault; C Carrat; François Lefèvre; M Bernoin; Bernard Charley
Type I IFN modulates the immune response induced by DNA vaccination to pseudorabies virus glycoprotein C.
Virology 2001;286(1):197-205.
1999: Chandra Somasundaram; H Takamatsu; C Andréoni; J C Audonnet; L Fischer; François Lefèvre; Bernard Charley
Enhanced protective response and immuno-adjuvant effects of porcine GM-CSF on DNA vaccination of pigs against Aujeszky's disease virus.
Veterinary immunology and immunopathology 1999;70(3-4):277-87.
1999: Avrelija Cencic; François Lefèvre; Srecko Koren; Claude La Bonnardière
Tetracycline-controlled expression of glycosylated porcine interferon-gamma in mammalian cells.
Animal biotechnology 1999;10(1-2):63-79.
1998: François Lefèvre; M Guillomot; Sabine D'Andréa; S Battegay; Claude La Bonnardière
Interferon-delta: the first member of a novel type I interferon family.
Biochimie 1998;80(8-9):779-88.
1998: François Lefèvre; Françoise Martinat-Botté; A Locatelli; P De Niu; Michel Terqui; Claude La Bonnardière
Intrauterine infusion of high doses of pig trophoblast interferons has no antiluteolytic effect in cyclic gilts.
Biology of reproduction 1998;58(4):1026-31.
1996: M Villar; François Lefèvre; H D Bradshaw; E Teissier du Cros
Molecular genetics of rust resistance in poplars (Melampsora larici-populina Kleb/Populus sp.) by bulked segregant analysis in a 2 x 2 factorial mating design.
Genetics 1996;143(1):531-6.
1994: Claude La Bonnardière; François Lefèvre; Bernard Charley
Interferon response in pigs: molecular and biological aspects.
Veterinary immunology and immunopathology 1994;43(1-3):29-36.
1994: Bernard Charley; L Lavenant; François Lefèvre
Coronavirus transmissible gastroenteritis virus-mediated induction of IFN alpha-mRNA in porcine leukocytes requires prior synthesis of soluble proteins.
Veterinary research 1994;25(1):29-36.
1993: François Lefèvre; V Boulay
A novel and atypical type one interferon gene expressed by trophoblast during early pregnancy.
The Journal of biological chemistry 1993;268(26):19760-8.
1991: Claude La Bonnardière; F Martinat-Botte; M Terqui; François Lefèvre; K Zouari; J Martal; Fuller W Bazer
Production of two species of interferon by Large White and Meishan pig conceptuses during the peri-attachment period.
Journal of reproduction and fertility 1991;91(2):469-78.
1990: François Lefèvre; F Martinat-Botté; M Guillomot; K Zouari; Bernard Charley; Claude La Bonnardière
Interferon-gamma gene and protein are spontaneously expressed by the porcine trophectoderm early in gestation.
European journal of immunology 1990;20(11):2485-90.
1990: François Lefèvre; D Mège; R L'Haridon; S Bernard; C De Vaureix; Claude La Bonnardière
Contribution of molecular biology to the study of the porcine interferon system.
Veterinary microbiology 1990;23(1-4):245-57.
1990: François Lefèvre; R L'Haridon; F Borras-Cuesta; Claude La Bonnardière
Production, purification and biological properties of an Escherichia coli-derived recombinant porcine alpha interferon.
The Journal of general virology 1990;71 ( Pt 5)():1057-63.