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Francesco Legge

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Disorders

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Physiology

Drug Resistance, Neoplasm

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Francesco Legge; Alessandro Lucidi; Gabriella Macchia; Pasquale A Margariti; Alessio Giuseppe Morganti; Marco Petrillo; Giovanni Scambia; Vito Carone; Vito Iannone; Gabriella Ferrandina
Completion surgery after concomitant chemoradiation in obese women with locally advanced cervical cancer: Evaluation of toxicity and outcome measures.
Marco Petrillo; Maddalena Borriello; Gilda Fuoco; Vito Iannone; Francesco Legge; Gabriella Ferrandina
Novel VEGF-independent strategies targeting tumor vasculature: clinical aspects.
Sandro Pignata; Carmela Pisano; Alberto Ravaioli; Vanda Salutari; Antonella Savarese; Laura Scaltriti; Giovanni Scambia; Paolo Scollo; Roberto Sorio; Stefano Tamberi; Maria Rosaria Valerio; Enrico Aitini; Alba Brandes; Enrico Breda; Pietro Del Medico; Massimo Di Maio; Antonio Febbraro; Gabriella Ferrandina; Antonella Ferro; Luigi Frigerio; Ciro Gallo; Vittorio Gebbia; Stefano Greggi; Francesco Legge; Alessandra Vernaglia Lombardi; Domenica Lorusso; Alessandro Morabito; Pietro Musso; Donato Natale; Francesco Perrone
Carboplatin plus paclitaxel versus carboplatin plus pegylated liposomal doxorubicin as first-line treatment for patients with ovarian cancer: the MITO-2 randomized phase III trial.

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All Publications

2013: Francesco Legge; Alessandro Lucidi; Gabriella Macchia; Pasquale A Margariti; Alessio Giuseppe Morganti; Marco Petrillo; Giovanni Scambia; Vito Carone; Vito Iannone; Gabriella Ferrandina
Completion surgery after concomitant chemoradiation in obese women with locally advanced cervical cancer: Evaluation of toxicity and outcome measures.
Acta oncologica (Stockholm, Sweden) 2013;52(1):166-73.
2012: Marco Petrillo; Maddalena Borriello; Gilda Fuoco; Vito Iannone; Francesco Legge; Gabriella Ferrandina
Novel VEGF-independent strategies targeting tumor vasculature: clinical aspects.
Current pharmaceutical design 2012;18(19):2702-12.
2011: Sandro Pignata; Carmela Pisano; Alberto Ravaioli; Vanda Salutari; Antonella Savarese; Laura Scaltriti; Giovanni Scambia; Paolo Scollo; Roberto Sorio; Stefano Tamberi; Maria Rosaria Valerio; Enrico Aitini; Alba Brandes; Enrico Breda; Pietro Del Medico; Massimo Di Maio; Antonio Febbraro; Gabriella Ferrandina; Antonella Ferro; Luigi Frigerio; Ciro Gallo; Vittorio Gebbia; Stefano Greggi; Francesco Legge; Alessandra Vernaglia Lombardi; Domenica Lorusso; Alessandro Morabito; Pietro Musso; Donato Natale; Francesco Perrone
Carboplatin plus paclitaxel versus carboplatin plus pegylated liposomal doxorubicin as first-line treatment for patients with ovarian cancer: the MITO-2 randomized phase III trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(27):3628-35.
2011: Francesco Legge; Amelia Paglia; Giovanni Scambia; Marco D'Asta; Gilda Fuoco; Gabriella Ferrandina
Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients.
BMC cancer 2011;11():214.
2008: Gabriella Ferrandina; Gabriella Macchia; Francesco Legge; Francesco Deodato; Franca Forni; Cinzia Digesù; Vito Carone; Alessio Giuseppe Morganti; Giovanni Scambia
Squamous cell carcinoma antigen in patients with locally advanced cervical carcinoma undergoing preoperative radiochemotherapy: association with pathological response to treatment and clinical outcome.
Oncology 2008;74(1-2):42-9.
2007: Gabriella Ferrandina; Francesco Legge; Anna Fagotti; Francesco Fanfani; Mariagrazia Distefano; Alessio Giuseppe Morganti; N Cellini; Giovanni Scambia
Preoperative concomitant chemoradiotherapy in locally advanced cervical cancer: safety, outcome, and prognostic measures.
Gynecologic oncology 2007;107(1 Suppl 1):S127-32.
2007: Anna Fagotti; Francesco Fanfani; Romina Longo; Francesco Legge; Alessandra Mari; Maria Lucia Gagliardi; Giovanni Scambia
Which role for pre-treatment laparoscopic staging?
Gynecologic oncology 2007;107(1 Suppl 1):S101-5.
2007: Gabriella Ferrandina; Giovanni Scambia; Francesco Legge; Marco Petrillo; Vanda Salutari
Ovarian cancer patients with "node-positive-only" Stage IIIC disease have a more favorable outcome than Stage IIIA/B.
Gynecologic oncology 2007;107(1):154-6.
2007: Gabriella Ferrandina; Francesco Legge; Valentina Mey; Sara Nannizzi; Simona Ricciardi; Marco Petrillo; Giacomo Corrado; Giovanni Scambia
A case of drug resistant clear cell ovarian cancer showing responsiveness to gemcitabine at first administration and at re-challenge.
Cancer chemotherapy and pharmacology 2007;60(3):459-61.
2007: Francesco Legge; D Eaton; R Molife; Gabriella Ferrandina; I Judson; J de Bono; S Kaye
Participation of patients with gynecological cancer in phase I clinical trials: two years experience in a major cancer center.
Gynecologic oncology 2007;104(3):551-6.
2006: Gabriella Ferrandina; Francesco Legge; Vanda Salutari; Amelia Paglia; Antonia Testa; Giovanni Scambia
Impact of pattern of recurrence on clinical outcome of ovarian cancer patients: clinical considerations.
European journal of cancer (Oxford, England : 1990) 2006;42(14):2296-302.
2006: Francesco Legge; Gabriella Ferrandina; Giovanni Scambia
From bio-molecular and technology innovations to clinical practice: focus on ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17 Suppl 7():vii46-8.
2006: Gabriella Ferrandina; Franco O Ranelletti; Francesco Legge; Vanda Salutari; Enrica Martinelli; Andrea Fattorossi; Domenica Lorusso; Gian Franco Zannoni; Valerio Gaetano Vellone; Amelia Paglia; Giovanni Scambia
Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2055-60.
2006: Grazia Graziani; Gabriella Ferrandina; Giacomo Pozzoli; Matteo Vergati; Alessia Muzi; Francesco Legge; Lucio Tentori; Giovanni Scambia; Pierluigi Navarra
Corticotropin-releasing hormone receptor-1 in human endometrial cancer.
Oncology reports 2006;15(2):375-9.
2005: Francesco Fanfani; Anna Fagotti; Gabriella Ferrandina; Giuseppe Bifulco; Francesco Legge; Domenica Lorusso; Luca Minelli; Giovanni Scambia
Increased cyclooxygenase-2 expression is associated with better clinical outcome in patients submitted to complete ablation for severe endometriosis.
Human reproduction (Oxford, England) 2005;20(10):2964-8.
2005: Francesco Legge; Gabriella Ferrandina; Vanda Salutari; Giovanni Scambia
Biological characterization of ovarian cancer: prognostic and therapeutic implications.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16 Suppl 4():iv95-101.
2005: Gabriella Ferrandina; Francesco Legge; Enrica Martinelli; Franco O Ranelletti; Gian Franco Zannoni; Libero Lauriola; Marco Gessi; Valerio Gallotta; Giovanni Scambia
Survivin expression in ovarian cancer and its correlation with clinico-pathological, surgical and apoptosis-related parameters.
British journal of cancer 2005;92(2):271-7.
2004: Gabriella Ferrandina; Gian Franco Zannoni; Franco O Ranelletti; Francesco Legge; Marco Gessi; Vanda Salutari; Valerio Gallotta; Libero Lauriola; Giovanni Scambia
Cyclooxygenase-2 expression in borderline ovarian tumors.
Gynecologic oncology 2004;95(1):46-51.
2004: Gian Franco Zannoni; Valerio Gallotta; Francesco Legge; Elisabetta Tarquini; Giovanni Scambia; Gabriella Ferrandina
Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report.
Gynecologic oncology 2004;94(1):226-8.
2004: Gabriella Ferrandina; Franco O Ranelletti; Francesco Legge; Marco Gessi; Vanda Salutari; Mariagrazia Distefano; Libero Lauriola; Gian Franco Zannoni; Enrica Martinelli; Giovanni Scambia
Prognostic role of the ratio between cyclooxygenase-2 in tumor and stroma compartments in cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):3117-23.
2004: Andrea Fattorossi; Alessandra Battaglia; Gabriella Ferrandina; Ferdinando Coronetta; Francesco Legge; Vanda Salutari; Giovanni Scambia
Neoadjuvant therapy changes the lymphocyte composition of tumor-draining lymph nodes in cervical carcinoma.
Cancer 2004;100(7):1418-28.
2004: Gabriella Ferrandina; Franco O Ranelletti; Vanda Salutari; Marco Gessi; Francesco Legge; Gian Franco Zannoni; Giovanni Scambia; Libero Lauriola
Expression of cyclooxygenase-2 (COX-2) in non-neoplastic and neoplastic vulvar epithelial lesions.
Gynecologic oncology 2004;92(2):537-44.
2004: Anna Fagotti; Gabriella Ferrandina; Francesco Fanfani; Francesco Legge; Libero Lauriola; Marco Gessi; Paola Castelli; Fabrizio Barbieri; Luca Minelli; Giovanni Scambia
Analysis of cyclooxygenase-2 (COX-2) expression in different sites of endometriosis and correlation with clinico-pathological parameters.
Human reproduction (Oxford, England) 2004;19(2):393-7.
2004: Andrea Fattorossi; Alessandra Battaglia; Gabriella Ferrandina; Alexia Buzzonetti; Francesco Legge; Vanda Salutari; Giovanni Scambia
Lymphocyte composition of tumor draining lymph nodes from cervical and endometrial cancer patients.
Gynecologic oncology 2004;92(1):106-15.
2003: Alessandra Battaglia; Gabriella Ferrandina; Alexia Buzzonetti; Paolo Malinconico; Francesco Legge; Vanda Salutari; Giovanni Scambia; Andrea Fattorossi
Lymphocyte populations in human lymph nodes. Alterations in CD4+ CD25+ T regulatory cell phenotype and T-cell receptor Vbeta repertoire.
Immunology 2003;110(3):304-12.
2003: Gabriella Ferrandina; Franco O Ranelletti; Libero Lauriola; Gian Franco Zannoni; Francesco Legge; Marco Gessi; Vanda Salutari; Giovanni Scambia
Cyclooxygenase-2 expression in lymph node metastasis of cervical and vulvar cancer.
Oncology reports 2003;10(6):1799-804.
2003: Gabriella Ferrandina; Franco O Ranelletti; Francesco Legge; Libero Lauriola; Vanda Salutari; Marco Gessi; Antonia Carla Testa; Ulrike Werner; Pierluigi Navarra; Giuseppe Tringali; Alessandra Battaglia; Giovanni Scambia
Celecoxib modulates the expression of cyclooxygenase-2, ki67, apoptosis-related marker, and microvessel density in human cervical cancer: a pilot study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(12):4324-31.
2003: Gabriella Ferrandina; Franco O Ranelletti; Francesco Legge; Libero Lauriola; Antonella Poerio; Gian Franco Zannoni; Daniela Smaniotto; Pasquale Alessandro Margariti; Gabriella Macchia; Giovanni Scambia
Cyclooxygenase-2 (COX-2) expression in locally advanced cervical cancer patients undergoing chemoradiation plus surgery.
International journal of radiation oncology, biology, physics 2003;55(1):21-7.
2002: Gabriella Ferrandina; Libero Lauriola; Gian Franco Zannoni; Mariagrazia Distefano; Francesco Legge; Vanda Salutari; Marco Gessi; Nicola Maggiano; Giovanni Scambia; Franco O Ranelletti
Expression of cyclooxygenase-2 (COX-2) in tumour and stroma compartments in cervical cancer: clinical implications.
British journal of cancer 2002;87(10):1145-52.
2002: Marcello Ceccaroni; Maurizio Genuardi; Francesco Legge; Emanuela Lucci-Cordisco; Stefania Carrara; Franca D'Amico; Stefano Greggi; Giovanni Scambia
BRCA1-related malignancies in a family presenting with von Recklinghausen's disease.
Gynecologic oncology 2002;86(3):375-8.
2002: Gabriella Ferrandina; Francesco Legge; Franco O Ranelletti; Gian Franco Zannoni; Nicola Maggiano; Antonella Evangelisti; Salvatore Mancuso; Giovanni Scambia; Libero Lauriola
Cyclooxygenase-2 expression in endometrial carcinoma: correlation with clinicopathologic parameters and clinical outcome.
Cancer 2002;95(4):801-7.
2002: Gabriella Ferrandina; Libero Lauriola; Gian Franco Zannoni; Anna Fagotti; Francesco Fanfani; Francesco Legge; Nicola Maggiano; Marco Gessi; S Mancuso; Franco O Ranelletti; Giovanni Scambia
Increased cyclooxygenase-2 (COX-2) expression is associated with chemotherapy resistance and outcome in ovarian cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(8):1205-11.
2002: Gabriella Ferrandina; Franco O Ranelletti; Libero Lauriola; Francesco Fanfani; Francesco Legge; M Mottolese; M R Nicotra; P G Natali; V H Zakut; Giovanni Scambia
Cyclooxygenase-2 (COX-2), epidermal growth factor receptor (EGFR), and Her-2/neu expression in ovarian cancer.
Gynecologic oncology 2002;85(2):305-10.
2002: Gabriella Ferrandina; Libero Lauriola; Mariagrazia Distefano; Gian Franco Zannoni; Marco Gessi; Francesco Legge; Nicola Maggiano; Salvatore Mancuso; A Capelli; Giovanni Scambia; Franco O Ranelletti
Increased cyclooxygenase-2 expression is associated with chemotherapy resistance and poor survival in cervical cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):973-81.
2001: Gabriella Ferrandina; Franco O Ranelletti; L M Larocca; Nicola Maggiano; Erika Fruscella; Francesco Legge; Giuseppe Santeusanio; Alessandro Bombonati; Salvatore Mancuso; Giovanni Scambia
Tamoxifen modulates the expression of Ki67, apoptosis, and microvessel density in cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2656-61.
2001: G Ferrandina; Francesco Legge; Anna Fagotti; Francesco Fanfani; Salvatore Mancuso; G Scambia
[Biological factors with prognostic significance in ovarian cancer].
Minerva ginecologica 2001;53(1 Suppl 1):40-5.
2001: Stefano Greggi; Francesco Legge; Salvatore Mancuso
[Familial ovarian carcinoma].
Minerva ginecologica 2001;53(1 Suppl 1):3-5.
2000: Stefano Greggi; F Parazzini; MP Paratore; L Chatenoud; Francesco Legge; Salvatore Mancuso; C La Vecchia
Risk factors for ovarian cancer in central Italy.
Gynecologic oncology 2000;79(1):50-4.