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Barbara Leggett

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Australia

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Whitehall Vicki; Tran Kayla; Umapathy Aarti; Grieu Fabienne; Hewitt Chelsee; Evans Tiffany-Jane; Ismail Tuty; Li Wei Qi; Collins Peter; Ravetto Paul; Leggett Barbara; Salto-Tellez Manuel; Soong Richie; Fox Stephen; Scott Rodney J; Dobrovic Alexander; Iacopetta Barry
A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting.
Leggett Barbara A; Worthley Daniel L
Synchronous colorectal cancer: not just bad luck?
Herath Nirmitha I; Purdie David M; Kew Michael C; Smith Jeffery L; Young Joanne; Leggett Barbara A; MacDonald Graeme A
Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.

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All Publications

2009: Whitehall Vicki; Tran Kayla; Umapathy Aarti; Grieu Fabienne; Hewitt Chelsee; Evans Tiffany-Jane; Ismail Tuty; Li Wei Qi; Collins Peter; Ravetto Paul; Leggett Barbara; Salto-Tellez Manuel; Soong Richie; Fox Stephen; Scott Rodney J; Dobrovic Alexander; Iacopetta Barry
A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting.
The Journal of molecular diagnostics : JMD 2009;11(6):543-52.
2009: Leggett Barbara A; Worthley Daniel L
Synchronous colorectal cancer: not just bad luck?
Gastroenterology 2009;137(5):1559-62.
2009: Herath Nirmitha I; Purdie David M; Kew Michael C; Smith Jeffery L; Young Joanne; Leggett Barbara A; MacDonald Graeme A
Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.
International journal of oncology 2009;35(5):1081-9.
2009: Walsh Michael D; Dent Owen F; Young Joanne P; Wright Caroline M; Barker Melissa A; Leggett Barbara A; Bokey Les; Chapuis Pierre H; Jass Jeremy R; Macdonald Graeme A
HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers.
International journal of cancer. Journal international du cancer 2009;125(5):1231-7.
2009: Kominami K; Nagasaka T; Cullings H M; Hoshizima N; Sasamoto H; Young J; Leggett B A; Tanaka N; Matsubara N
Methylation in p14(ARF) is frequently observed in colorectal cancer with low-level microsatellite instability.
The Journal of international medical research 2009;37(4):1038-45.
2009: Herath N I; Doecke J; Spanevello M D; Leggett B A; Boyd A W
Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.
British journal of cancer 2009;100(7):1095-102.
2008: Loh Kim; Chia June A; Greco Sonia; Cozzi Sarah-Jane; Buttenshaw Ron L; Bond Catherine E; Simms Lisa A; Pike Tanya; Young Joanne P; Jass Jeremy R; Spring Kevin J; Leggett Barbara A; Whitehall Vicki L J
Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development.
Genes, chromosomes & cancer 2008;47(6):449-60.
2007: Worthley Daniel-L; Whitehall Vicki-L; Spring Kevin-J; Leggett Barbara-A
Colorectal carcinogenesis: road maps to cancer.
World journal of gastroenterology : WJG 2007;13(28):3784-91.
2007: Walsh Michael D; Young Joanne P; Leggett Barbara A; Williams Stephanie H; Jass Jeremy R; McGuckin Michael A
The MUC13 cell surface mucin is highly expressed by human colorectal carcinomas.
Human pathology 2007;38(6):883-92.
2007: Herath Nirmitha I; Walsh Michael D; Kew Michael; Smith Jeffery L; Jass Jeremy R; Young Joanne; Leggett Barbara A; Macdonald Graeme A
Silencing of O6-methylguanine DNA methyltransferase in the absence of promoter hypermethylation in hepatocellular carcinomas from Australia and South Africa.
Oncology reports 2007;17(4):817-22.
2007: Lynch Brigid M; Baade Peter; Fritschi Lin; Leggett Barbara; Owen Neville; Pakenham Kenneth; Newman Beth; Aitken Joanne F
Modes of presentation and pathways to diagnosis of colorectal cancer in Queensland.
The Medical journal of Australia 2007;186(6):288-91.
2006: Spring Kevin J; Zhao Zhen Zhen; Karamatic Rozemary; Walsh Michael D; Whitehall Vicki L J; Pike Tanya; Simms Lisa A; Young Joanne; James Michael; Montgomery Grant W; Appleyard Mark; Hewett David; Togashi Kazutomo; Jass Jeremy R; Leggett Barbara A
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.
Gastroenterology 2006;131(5):1400-7.
2006: Chow Elizabeth; Lipton Lara; Lynch Elly; D'Souza Rebecca; Aragona Clelia; Hodgkin Lindy; Brown Gregor; Winship Ingrid; Barker Melissa; Buchanan Daniel; Cowie Shannon; Nasioulas Steve; du Sart Desiree; Young Joanne; Leggett Barbara; Jass Jeremy; Macrae Finlay
Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH.
Gastroenterology 2006;131(1):30-9.
2006: Weisenberger Daniel J; Siegmund Kimberly D; Campan Mihaela; Young Joanne; Long Tiffany I; Faasse Mark A; Kang Gyeong Hoon; Widschwendter Martin; Weener Deborah; Buchanan Daniel; Koh Hoey; Simms Lisa; Barker Melissa; Leggett Barbara; Levine Joan; Kim Myungjin; French Amy J; Thibodeau Stephen N; Jass Jeremy; Haile Robert; Laird Peter W
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Nature genetics 2006;38(7):787-93.
2006: Lynch Brigid M; Owen Neville; Newman Beth; Pakenham Ken; Leggett Barbara; Dunn Jeff; Aitken Joanne F
Reliability of a measure of prediagnosis physical activity for cancer survivors.
Medicine and science in sports and exercise 2006;38(4):715-9.
2006: Wynter Coral V A; Kambara Takeshi; Walsh Michael D; Leggett Barbara A; Young Joanne; Jass Jeremy R
DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.
International journal of cancer. Journal international du cancer 2006;118(4):907-15.
2006: Herath Nirmitha I; Leggett Barbara A; MacDonald Graeme A
Review of genetic and epigenetic alterations in hepatocarcinogenesis.
Journal of gastroenterology and hepatology 2006;21(1 Pt 1):15-21.
2006: Simpson Fiona; Lammerts van Bueren Kelly; Butterfield Natalie; Bennetts Jennifer S; Bowles Josephine; Adolphe Christelle; Simms Lisa A; Young Joanne; Walsh Michael D; Leggett Barbara; Fowles Lindsay F; Wicking Carol
The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b.
Experimental cell research 2006;312(1):73-85.
2006: Dunn Jeff; Lynch Brigid; Rinaldis Machelle; Pakenham Kenneth; McPherson Lyn; Owen Neville; Leggett Barbara; Newman Beth; Aitken Joanne
Dimensions of quality of life and psychosocial variables most salient to colorectal cancer patients.
Psycho-oncology 2006;15(1):20-30.
2006: Chia June A; Simms Lisa A; Cozzi Sarah-Jane; Young Joanne; Jass Jeremy R; Walsh Michael D; Spring Kevin J; Leggett Barbara A; Whitehall Vicki L J
SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers.
BMC cancer 2006;6():252.
2005: Hughes Karen; Leggett Barbara; Del Mar Christopher; Croese John; Fairley Stephen; Masson John; Aitken Joanne; Clavarino Alexandra; Janda Monika; Stanton Warren R; Tong Shilu; Newman Beth
Guaiac versus immunochemical tests: faecal occult blood test screening for colorectal cancer in a rural community.
Australian and New Zealand journal of public health 2005;29(4):358-64.
2005: Graves Nicholas; McKinnon Loretta; Leggett Barbara; Newman Beth
Re-interpreting the data on the cost and effectiveness of population screening for colorectal cancer in Australia.
Australia and New Zealand health policy 2005;2():10.
2005: Young Joanne; Barker Melissa A; Simms Lisa A; Walsh Michael D; Biden Kelli G; Buchanan Daniel; Buttenshaw Ron; Whitehall Vicki L J; Arnold Sven; Jackson Leigh; Kambara Takeshi; Spring Kevin J; Jenkins Mark A; Walker Graeme J; Hopper John L; Leggett Barbara A; Jass Jeremy R
Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(3):254-63.
2005: Wright C M; Dent O F; Newland R C; Barker M; Chapuis P H; Bokey E L; Young J P; Leggett B A; Jass J R; Macdonald G A
Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma.
Gut 2005;54(1):103-8.
2004: Nagasaka Takeshi; Sasamoto Hiromi; Notohara Kenji; Cullings Harry M; Takeda Masanori; Kimura Keigo; Kambara Takeshi; MacPhee Donald G; Young Joanne; Leggett Barbara A; Jass Jeremy R; Tanaka Noriaki; Matsubara Nagahide
Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(22):4584-94.
2004: Clavarino Alexandra M; Janda Monika; Hughes Karen L; Del Mar Christopher; Tong Shilu; Stanton Warren R; Aitken Joanne F; Leggett Barbara A; Newman Beth
The view from two sides: a qualitative study of community and medical perspectives on screening for colorectal cancer using FOBT.
Preventive medicine 2004;39(3):482-90.
2004: Kambara T; Simms L A; Whitehall V L J; Spring K J; Wynter C V A; Walsh M D; Barker M A; Arnold S; McGivern A; Matsubara N; Tanaka N; Higuchi T; Young J; Jass J R; Leggett B A
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.
Gut 2004;53(8):1137-44.
2004: Herath Nirmitha I; Walsh Michael D; Kew Michael C; Young Joanne; Leggett Barbara A; Macdonald Graeme A
Cadherin/catenin complex appears to be intact in hepatocellular carcinomas from Australia and South Africa.
Journal of gastroenterology and hepatology 2004;19(6):676-82.
2004: Kambara Takeshi; Whitehall Vicki L J; Spring Kevin J; Barker Melissa A; Arnold Sven; Wynter Coral V A; Matsubara Nagahide; Tanaka Noriaki; Young Joanne P; Leggett Barbara A; Jass Jeremy R
Role of inherited defects of MYH in the development of sporadic colorectal cancer.
Genes, chromosomes & cancer 2004;40(1):1-9.
2004: Mori Yuriko; Yin Jing; Sato Fumiaki; Sterian Anca; Simms Lisa A; Selaru Florin M; Schulmann Karsten; Xu Yan; Olaru Andreea; Wang Suna; Deacu Elena; Abraham John M; Young Joanne; Leggett Barbara A; Meltzer Stephen J
Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.
Cancer research 2004;64(7):2434-8.
2004: Wynter C V A; Walsh M D; Higuchi T; Leggett B A; Young J; Jass J R
Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.
Gut 2004;53(4):573-80.
2004: McGivern A; Wynter C V A; Whitehall V L J; Kambara T; Spring K J; Walsh M D; Barker M A; Arnold S; Simms L A; Leggett B A; Young J; Jass J R
Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.
Familial cancer 2004;3(2):101-7.
2003: Michael-Robinson Julie M; Pandeya Nirmala; Cummings Margaret C; Walsh Michael D; Young Joanne P; Leggett Barbara A; Purdie David M; Jass Jeremy R; Radford-Smith Graham L
Fas ligand and tumour counter-attack in colorectal cancer stratified according to microsatellite instability status.
The Journal of pathology 2003;201(1):46-54.
2003: Leggett Barbara A; Young Joanne P; Barker Melissa
Peutz-Jeghers syndrome: genetic screening.
Expert review of anticancer therapy 2003;3(4):518-24.
2003: Mori Yuriko; Selaru Florin M; Sato Fumiaki; Yin Jing; Simms Lisa A; Xu Yan; Olaru Andreea; Deacu Elena; Wang Suna; Taylor Jennifer M; Young Joanne; Leggett Barbara; Jass Jeremy R; Abraham John M; Shibata David; Meltzer Stephen J
The impact of microsatellite instability on the molecular phenotype of colorectal tumors.
Cancer research 2003;63(15):4577-82.
2003: Jass J R; Barker M; Fraser L; Walsh M D; Whitehall V L J; Gabrielli B; Young J; Leggett B A
APC mutation and tumour budding in colorectal cancer.
Journal of clinical pathology 2003;56(1):69-73.
2003: Dunn Jeff; Lynch Brigid; Aitken Joanne; Leggett Barbara; Pakenham Kenneth; Newman Beth
Quality of life and colorectal cancer: a review.
Australian and New Zealand journal of public health 2003;27(1):41-53.
2003: Janda Monika; Stanton Warren R; Hughes Karen; Del Mar Christopher; Clavarino Alexandra; Aitken Joanne F; Tong Shilu; Short Leonie; Leggett Barbara; Newman Beth
Knowledge, attitude and intentions related to colorectal cancer screening using faecal occult blood tests in a rural Australian population.
Asia-Pacific journal of public health / Asia-Pacific Academic Consortium for Public Health 2003;15(1):50-6.
2002: Young Joanne; Barker Melissa; Fraser Leigh; Walsh Michael D; Spring Kevin; Biden Kelli G; Hopper John L; Leggett Barbara A; Jass Jeremy R
Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes.
Pathology 2002;34(6):529-33.
2002: Sato Fumiaki; Shibata David; Harpaz Noam; Xu Yan; Yin Jing; Mori Yuriko; Wang Suna; Olaru Andreea; Deacu Elena; Selaru Florin M; Kimos Martha C; Hytiroglou Prodromos; Young Joanne; Leggett Barbara; Gazdar Adi F; Toyooka Shinichi; Abraham John M; Meltzer Stephen J
Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma.
Cancer research 2002;62(23):6820-2.
2002: Whitehall Vicki L J; Wynter Coral V A; Walsh Michael D; Simms Lisa A; Purdie David; Pandeya Nirmala; Young Joanne; Meltzer Stephen J; Leggett Barbara A; Jass Jeremy R
Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.
Cancer research 2002;62(21):6011-4.
2002: Jass Jeremy R; Whitehall Vicki L J; Young Joanne; Leggett Barbara; Meltzer Stephen J; Matsubara Nagahide; Fishel Richard
Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002.
Cancer research 2002;62(20):5988-9; author reply 5989-90.
2002: Jass Jeremy R; Whitehall Vicki L J; Young Joanne; Leggett Barbara A
Emerging concepts in colorectal neoplasia.
Gastroenterology 2002;123(3):862-76.
2002: Wong Chung Fai; Liyou Nancy; Leggett Barbara; Young Joanne; Johnson Anthony; McManus Michael E
Association of the SULT1A1 R213H polymorphism with colorectal cancer.
Clinical and experimental pharmacology & physiology 2002;29(9):754-8.
2002: Ladhams Andrew; Schmidt Chris; Sing Garwin; Butterworth Lesley; Fielding George; Tesar Paul; Strong Russell; Leggett Barbara; Powell Lawrie; Maddern Guy; Ellem Kay; Cooksley Graham
Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells.
Journal of gastroenterology and hepatology 2002;17(8):889-96.
2002: Mori Yuriko; Sato Fumiaki; Selaru Florin M; Olaru Andreea; Perry Kellie; Kimos Martha C; Tamura Gen; Matsubara Nagahide; Wang Suna; Xu Yan; Yin Jing; Zou Tong-Tong; Leggett Barbara; Young Joanne; Nukiwa Toshihiro; Stine O Colin; Abraham John M; Shibata David; Meltzer Stephen J
Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.
Cancer research 2002;62(13):3641-5.
2002: Jass J R; Walsh M D; Barker M; Simms L A; Young J; Leggett B A
Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability.
European journal of cancer (Oxford, England : 1990) 2002;38(7):858-66.
2002: Herath Nirmitha I; Kew Michael C; Walsh Michael D; Young Joanne; Powell Lawrie W; Leggett Barbara A; MacDonald Graeme A
Reciprocal relationship between methylation status and loss of heterozygosity at the p14(ARF) locus in Australian and South African hepatocellular carcinomas.
Journal of gastroenterology and hepatology 2002;17(3):301-7.
2002: Young J; Barker M; Robertson T; Nasioulas S; Tannenberg A; Buttenshaw R L; Knight N; Jass J R; Leggett B A
A case of myoepithelial carcinoma displaying biallelic inactivation of the tumour suppressor gene APC in a patient with familial adenomatous polyposis.
Journal of clinical pathology 2002;55(3):230-1.
2002: Janda Monika; Hughes Karen; Tong Shilu; Stanton Warren R; Aitken Joanne; Clavarino Alexandra; Short Leonie; Del Mar Christopher; Leggett Barbara; Newman Beth
Faecal occult blood test: current practice in a rural Queensland community.
The Australian journal of rural health 2002;10(1):57-64.
2002: Lindor Noralane M; Burgart Lawrence J; Leontovich Olga; Goldberg Richard M; Cunningham Julie M; Sargent Daniel J; Walsh-Vockley Catherine; Petersen Gloria M; Walsh Michael D; Leggett Barbara A; Young Joanne P; Barker Melissa A; Jass Jeremy R; Hopper John; Gallinger Steve; Bapat Bharati; Redston Mark; Thibodeau Stephen N
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):1043-8.
2002: Jass Jereny R; Young Joanne; Leggett Barbara A
Evolution of colorectal cancer: change of pace and change of direction.
Journal of gastroenterology and hepatology 2002;17(1):17-26.
2001: Young J; Simms L A; Biden K G; Wynter C; Whitehall V; Karamatic R; George J; Goldblatt J; Walpole I; Robin S A; Borten M M; Stitz R; Searle J; McKeone D; Fraser L; Purdie D R; Podger K; Price R; Buttenshaw R; Walsh M D; Barker M; Leggett B A; Jass J R
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.
The American journal of pathology 2001;159(6):2107-16.
2001: Mori Y; Yin J; Rashid A; Leggett B A; Young J; Simms L; Kuehl P M; Langenberg P; Meltzer S J; Stine O C
Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability.
Cancer research 2001;61(16):6046-9.
2001: Michael-Robinson J M; Reid L E; Purdie D M; Biemer-Hüttmann A E; Walsh M D; Pandeya N; Simms L A; Young J P; Leggett B A; Jass J R; Radford-Smith G L
Proliferation, apoptosis, and survival in high-level microsatellite instability sporadic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2347-56.
2001: Michael-Robinson J M; Biemer-Hüttmann A; Purdie D M; Walsh M D; Simms L A; Biden K G; Young J P; Leggett B A; Jass J R; Radford-Smith G L
Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status.
Gut 2001;48(3):360-6.
2001: Whitehall V L; Walsh M D; Young J; Leggett B A; Jass J R
Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability.
Cancer research 2001;61(3):827-30.
2001: Leggett B A; Devereaux B; Biden K; Searle J; Young J; Jass J
Hyperplastic polyposis: association with colorectal cancer.
The American journal of surgical pathology 2001;25(2):177-84.
2001: Young J; Biden K G; Simms L A; Huggard P; Karamatic R; Eyre H J; Sutherland G R; Herath N; Barker M; Anderson G J; Fitzpatrick D R; Ramm G A; Jass J R; Leggett B A
HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):265-70.
2000: Jass J R; Young J; Leggett B A
Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum.
Histopathology 2000;37(4):295-301.
2000: Wright C M; Dent O F; Barker M; Newland R C; Chapuis P H; Bokey E L; Young J P; Leggett B A; Jass J R; Macdonald G A
Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer.
The British journal of surgery 2000;87(9):1197-202.
2000: Jass J R; Iino H; Ruszkiewicz A; Painter D; Solomon M J; Koorey D J; Cohn D; Furlong K L; Walsh M D; Palazzo J; Edmonston T B; Fishel R; Young J; Leggett B A
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
Gut 2000;47(1):43-9.
2000: Iino H; Simms L; Young J; Arnold J; Winship I M; Webb S I; Furlong K L; Leggett B; Jass J R
DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
Gut 2000;47(1):37-42.
2000: Biemer-Hüttmann A E; Walsh M D; McGuckin M A; Simms L A; Young J; Leggett B A; Jass J R
Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1909-16.
2000: Herath N I; Kew M C; Whitehall V L; Walsh M D; Jass J R; Khanna K K; Young J; Powell L W; Leggett B A; Macdonald G A
p73 is up-regulated in a subset of hepatocellular carcinomas.
Hepatology (Baltimore, Md.) 2000;31(3):601-5.
2000: Jass J R; Constable L; Sutherland R; Winterford C; Walsh M D; Young J; Leggett B A
Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissue.
Histopathology 2000;36(2):116-20.
1999: Macdonald G A; Tarish J; Whitehall V J; McCann S J; Mellick G D; Buttenshaw R L; Johnson A G; Young J; Leggett B A
No evidence of increased risk of colorectal cancer in individuals heterozygous for the Cys282Tyr haemochromatosis mutation.
Journal of gastroenterology and hepatology 1999;14(12):1188-91.
1999: Wynter C V; Simms L A; Buttenshaw R L; Biden K G; Young J; Leggett B A; Conrad R J; Schoch E M; Jass J R; Praga Pillay S
Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability.
The Journal of pathology 1999;189(3):319-25.
1999: Brix L A; Barnett A C; Duggleby R G; Leggett B; McManus M E
Analysis of the substrate specificity of human sulfotransferases SULT1A1 and SULT1A3: site-directed mutagenesis and kinetic studies.
Biochemistry 1999;38(32):10474-9.
1999: Winterford C M; Walsh M D; Leggett B A; Jass J R
Ultrastructural localization of epithelial mucin core proteins in colorectal tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(8):1063-74.
1999: Biemer-Hüttmann A E; Walsh M D; McGuckin M A; Ajioka Y; Watanabe H; Leggett B A; Jass J R
Immunohistochemical staining patterns of MUC1, MUC2, MUC4, and MUC5AC mucins in hyperplastic polyps, serrated adenomas, and traditional adenomas of the colorectum.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(8):1039-48.
1999: Jass J R; Biden K G; Cummings M C; Simms L A; Walsh M; Schoch E; Meltzer S J; Wright C; Searle J; Young J; Leggett B A
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
Journal of clinical pathology 1999;52(6):455-60.
1999: Biden K G; Simms L A; Cummings M; Buttenshaw R; Schoch E; Searle J; Gobe G; Jass J R; Meltzer S J; Leggett B A; Young J
Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability.
Oncogene 1999;18(5):1245-9.
1999: Iino H; Jass J R; Simms L A; Young J; Leggett B; Ajioka Y; Watanabe H
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?
Journal of clinical pathology 1999;52(1):5-9.
1998: Simms L A; Radford-Smith G; Biden K G; Buttenshaw R; Cummings M; Jass J R; Young J; Meltzer S J; Leggett B A
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers.
Oncogene 1998;17(15):2003-8.
1998: Wicking C; Simms L A; Evans T; Walsh M; Chawengsaksophak K; Beck F; Chenevix-Trench G; Young J; Jass J; Leggett B; Wainwright B
CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.
Oncogene 1998;17(5):657-9.
1998: Jass J R; Do K A; Simms L A; Iino H; Wynter C; Pillay S P; Searle J; Radford-Smith G; Young J; Leggett B
Morphology of sporadic colorectal cancer with DNA replication errors.
Gut 1998;42(5):673-9.
1998: Young J; Simms L A; Tarish J; Buttenshaw R; Knight N; Anderson G J; Bell A; Leggett B
A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9.
Human mutation 1998;11(6):450-5.
1997: Leggett B A; Young J P; Biden K; Buttenshaw R L; Knight N; Cowen A E
Severe upper gastrointestinal polyposis associated with sparse colonic polyposis in a familial adenomatous polyposis family with an APC mutation at codon 1520.
Gut 1997;41(4):518-21.
1997: Souza R F; Yin J; Smolinski K N; Zou T T; Wang S; Shi Y Q; Rhyu M G; Cottrell J; Abraham J M; Biden K; Simms L; Leggett B; Bova G S; Frank T; Powell S M; Sugimura H; Young J; Harpaz N; Shimizu K; Matsubara N; Meltzer S J
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors.
Cancer research 1997;57(12):2350-3.
1997: Simms L A; Zou T T; Young J; Shi Y Q; Lei J; Appel R; Rhyu M G; Sugimura H; Chenevix-Trench G; Souza R F; Meltzer S J; Leggett B A
Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers.
Oncogene 1997;14(21):2613-8.
1997: Leggett B A; Cornwell M; Thomas L R; Buttenshaw R L; Searle J; Young J; Ward M
Characteristics of metachronous colorectal carcinoma occurring despite colonoscopic surveillance.
Diseases of the colon and rectum 1997;40(5):603-8.
1997: Biden K; Young J; Buttenshaw R; Searle J; Cooksley G; Xu D B; Leggett B
Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population.
Hepatology (Baltimore, Md.) 1997;25(3):593-7.
1997: Souza R F; Lei J; Yin J; Appel R; Zou T T; Zhou X; Wang S; Rhyu M G; Cymes K; Chan O; Park W S; Krasna M J; Greenwald B D; Cottrell J; Abraham J M; Simms L; Leggett B; Young J; Harpaz N; Meltzer S J
A transforming growth factor beta 1 receptor type II mutation in ulcerative colitis-associated neoplasms.
Gastroenterology 1997;112(1):40-5.
1996: Souza R F; Appel R; Yin J; Wang S; Smolinski K N; Abraham J M; Zou T T; Shi Y Q; Lei J; Cottrell J; Cymes K; Biden K; Simms L; Leggett B; Lynch P M; Frazier M; Powell S M; Harpaz N; Sugimura H; Young J; Meltzer S J
Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours.
Nature genetics 1996;14(3):255-7.
1996: Souza R F; Garrigue-Antar L; Lei J; Yin J; Appel R; Vellucci V F; Zou T T; Zhou X; Wang S; Rhyu M G; Cymes K; Chan O; Park W S; Krasna M J; Greenwald B D; Cottrell J; Abraham J M; Simms L; Leggett B; Young J; Harpaz N; Reiss M; Meltzer S J
Alterations of transforming growth factor-beta 1 receptor type II occur in ulcerative colitis-associated carcinomas, sporadic colorectal neoplasms, and esophageal carcinomas, but not in gastric neoplasms.
Human cell : official journal of Human Cell Research Society 1996;9(3):229-36.
1995: Crawford D H; Powell L W; Leggett B A; Francis J S; Fletcher L M; Webb S I; Halliday J W; Jazwinska E C
Evidence that the ancestral haplotype in Australian hemochromatosis patients may be associated with a common mutation in the gene.
American journal of human genetics 1995;57(2):362-7.
1995: Leggett B; Young J; Buttenshaw R; Thomas L; Young B; Chenevix-Trench G; Searle J; Ward M
Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region.
British journal of cancer 1995;71(5):1070-3.
1995: Young J; Searle J; Buttenshaw R; Thomas L; Ward M; Chenevix-Trench G; Leggett B
An Alu VpA marker on chromosome I demonstrates that replication errors manifest at the adenoma-carcinoma transition in sporadic colorectal tumors.
Genes, chromosomes & cancer 1995;12(4):251-4.
1994: Gustafson C E; Young J; Leggett B; Searle J; Chenevix-Trench G
Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours.
British journal of cancer 1994;70(3):395-7.
1994: Young J; Buttenshaw R; Butterworth L; Ward M; Searle J; Leggett B; Chenevix-Trench G
Association of the SS genotype of the L-myc gene and loss of 18q sequences with a worse clinical prognosis in colorectal cancers.
Oncogene 1994;9(4):1053-6.
1993: Leggett B A; Thomas L R; Knight N; Healey S; Chenevix-Trench G; Searle J
Exclusion of APC and MCC as the gene defect in one family with familial juvenile polyposis.
Gastroenterology 1993;105(5):1313-6.
1993: Young J; Leggett B; Ward M; Thomas L; Buttenshaw R; Searle J; Chenevix-Trench G
Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas.
Oncogene 1993;8(3):671-5.
1993: Leggett B A; Fletcher L M; Ramm G A; Powell L W; Halliday J W
Differential regulation of ferritin H and L subunit mRNA during inflammation and long-term iron overload.
Journal of gastroenterology and hepatology 1993;8(1):21-7.
1993: Young J; Leggett B; Gustafson C; Ward M; Searle J; Thomas L; Buttenshaw R; Chenevix-Trench G
Genomic instability occurs in colorectal carcinomas but not in adenomas.
Human mutation 1993;2(5):351-4.
1990: Leggett B A; Brown N N; Bryant S J; Duplock L; Powell L W; Halliday J W
Factors affecting the concentrations of ferritin in serum in a healthy Australian population.
Clinical chemistry 1990;36(7):1350-5.
1990: Leggett B A; Halliday J W; Brown N N; Bryant S; Powell L W
Prevalence of haemochromatosis amongst asymptomatic Australians.
British journal of haematology 1990;74(4):525-30.
1989: Leggett B A; Powell L W; Halliday J W
Laboratory markers of alcoholism.
Digestive diseases (Basel, Switzerland) 1989;7(3):125-34.

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