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Chantal Legrand

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Chemicals & Drugs

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Ibtissem Djaafri; Brigitte Arbeille; Valérie Labas; Chantal Legrand; Monique Lemesle; Pascal Maurice; SAMIA MOURAH; Joëlle Vinh; Françoise Fauvel-Lafeve
Platelet type III collagen binding protein (TIIICBP) presents high biochemical and functional similarities with kindlin-3.
Dounia Gadi; Chantal Legrand; Abdelkhaleq Legssyer; Mohammed Aziz; Mohamed Berrabah; Mohamed Bnouham; Arlette Bruel; Françoise Fauvel-Lafeve; Abderrahim Ziyyat; Hassane Mekhfi
Flavonoids purified from parsley inhibit human blood platelet aggregation and adhesion to collagen under flow.
N Peyri; M Berard; Françoise Fauvel-Lafeve; V Trochon; Brigitte Arbeille; He Lu; Chantal Legrand; Michel Crepin
Breast tumor cells transendothelial migration induces endothelial cell anoikis through extracellular matrix degradation.

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All Publications

2012: Ibtissem Djaafri; Brigitte Arbeille; Valérie Labas; Chantal Legrand; Monique Lemesle; Pascal Maurice; SAMIA MOURAH; Joëlle Vinh; Françoise Fauvel-Lafeve
Platelet type III collagen binding protein (TIIICBP) presents high biochemical and functional similarities with kindlin-3.
Biochimie 2012;94(2):416-26.
2012: Dounia Gadi; Chantal Legrand; Abdelkhaleq Legssyer; Mohammed Aziz; Mohamed Berrabah; Mohamed Bnouham; Arlette Bruel; Françoise Fauvel-Lafeve; Abderrahim Ziyyat; Hassane Mekhfi
Flavonoids purified from parsley inhibit human blood platelet aggregation and adhesion to collagen under flow.
Journal of complementary & integrative medicine 2012;9():Article 19.
2009: N Peyri; M Berard; Françoise Fauvel-Lafeve; V Trochon; Brigitte Arbeille; He Lu; Chantal Legrand; Michel Crepin
Breast tumor cells transendothelial migration induces endothelial cell anoikis through extracellular matrix degradation.
Anticancer research 2009;29(6):2347-55.
2009: Julien Pêcher; Viviane Pires; Ibtissem Djaafri; Sophie Da Nascimento; Françoise Fauvel-Lafève; Chantal Legrand; Pascal Sonnet
Circular dichroism studies of type III collagen mimetic peptides with anti- or pro-aggregant activities on human platelets.
European journal of medicinal chemistry 2009;44(6):2643-50.
2009: Sébastien Augustin; M Berard; Sabine Kellaf; N Peyri; Françoise Fauvel-Lafève; Chantal Legrand; Lu He; Michel Crépin
Matrix metalloproteinases are involved in both type I (apoptosis) and type II (autophagy) cell death induced by sodium phenylacetate in MDA-MB-231 breast tumour cells.
Anticancer research 2009;29(4):1335-43.
2008: Alexandre Kauskot; Márcia R Cominetti; O H P Ramos; Iga Bechyne; Jean-Marie Renard; Marc F Hoylaerts; Michel Crepin; Chantal Legrand; Heloisa S Selistre-de-Araujo; Arnaud Bonnefoy
Hemostatic effects of recombinant DisBa-01, a disintegrin from Bothrops alternatus.
Frontiers in bioscience : a journal and virtual library 2008;13():6604-16.
2008: O H P Ramos; Alexandre Kauskot; Márcia R Cominetti; Iga Bechyne; Carmen L Salla Pontes; Fabrice Chareyre; Jan Manent; Roger Vassy; Marco Giovannini; Chantal Legrand; Heloisa S Selistre-de-Araujo; Michel Crépin; Arnaud Bonnefoy
A novel alpha(v)beta (3)-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis.
Clinical & experimental metastasis 2008;25(1):53-64.
2007: Viviane Pires; Julien Pêcher; Sophie Da Nascimento; Pascal Maurice; Arnaud Bonnefoy; Alexandra Dassonville; Carole Amant; Françoise Fauvel-Lafève; Chantal Legrand; Jacques Rochette; Pascal Sonnet
Type III collagen mimetic peptides designed with anti- or pro-aggregant activities on human platelets.
European journal of medicinal chemistry 2007;42(5):694-701.
2007: Alexandre Kauskot; Jan Manent; Fabrice Chareyre; Márcia Cominetti; Martine Chopin; Marco Giovannini; Chantal Legrand; Arnaud Bonnefoy
[Bioluminescent imaging to monitor tumor progression and metastasis in live animal].
Journal de la Société de biologie 2007;201(3):223-8.
2006: Pascal Maurice; Ludovic Waeckel; Viviane Pires; Pascal Sonnet; Monique Lemesle; Brigitte Arbeille; Jany Vassy; Jacques Rochette; Chantal Legrand; Françoise Fauvel-Lafève
The platelet receptor for type III collagen (TIIICBP) is present in platelet membrane lipid microdomains (rafts).
Histochemistry and cell biology 2006;125(4):407-17.
2006: Pascal Maurice; Viviane Pires; Carole Amant; Alexandre Kauskot; Sophie Da Nascimento; Pascal Sonnet; Jacques Rochette; Chantal Legrand; Françoise Fauvel-Lafeve; Arnaud Bonnefoy
Antithrombotic effect of the type III collagen-related octapeptide (KOGEOGPK) in the mouse.
Vascular pharmacology 2006;44(1):42-9.
2005: Mony Frojmovic; Benoit Labarthe; Chantal Legrand
Inhibition and reversal of platelet aggregation by alphaIIbbeta3 antagonists depends on the anticoagulant and flow conditions: differential effects of Abciximab and Lamifiban.
British journal of haematology 2005;131(3):348-55.
2005: Noëlia Gomes; Chantal Legrand; Françoise Fauvel-Lafève
Shear stress induced release of von Willebrand factor and thrombospondin-1 in HUVEC extracellular matrix enhances breast tumour cell adhesion.
Clinical & experimental metastasis 2005;22(3):215-23.
2004: Pascal Maurice; Chantal Legrand; Françoise Fauvel-Lafeve
Platelet adhesion and signaling induced by the octapeptide primary binding sequence (KOGEOGPK) from type III collagen.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1339-47.
2004: Marie Laure Ancelin; Sylvie Chollet-Martin; Marie-Astrid Hervé; Chantal Legrand; Jamel El Benna; Martine Perrot-Applanat
Vascular endothelial growth factor VEGF189 induces human neutrophil chemotaxis in extravascular tissue via an autocrine amplification mechanism.
Laboratory investigation; a journal of technical methods and pathology 2004;84(4):502-12.
2004: Véronique Trochon-Joseph; Dominique Martel-Renoir; Lluis M Mir; Annick Thomaïdis; Paule Opolon; Elisabeth Connault; Hong Li; Christophe Grenet; Françoise Fauvel-Lafève; Jeannette Soria; Chantal Legrand; Claudine Soria; Michel Perricaudet; He Lu
Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin.
Cancer research 2004;64(6):2062-9.
2004: Noëlia Gomes; Jany Vassy; Claude Lebos; Brigitte Arbeille; Chantal Legrand; Françoise Fauvel-Lafeve
Breast adenocarcinoma cell adhesion to the vascular subendothelium in whole blood and under flow conditions: effects of alphavbeta3 and alphaIIbbeta3 antagonists.
Clinical & experimental metastasis 2004;21(6):553-61.
2003: Noëlia Gomes; M Berard; Jany Vassy; N Peyri; Chantal Legrand; Françoise Fauvel-Lafeve
Shear stress modulates tumour cell adhesion to the endothelium.
Biorheology 2003;40(1-3):41-5.
2002: Anne Saumet; Nando de Jesus; Chantal Legrand; Véronique Dubernard
Association of thrombospondin-1 with the actin cytoskeleton of human thrombin-activated platelets through an alphaIIbbeta3- or CD36-independent mechanism.
The Biochemical journal 2002;363(Pt 3):473-82.
2001: E Monnet; Hilde Depraetere; Chantal Legrand; Hans Deckmyn; Françoise Fauvel-Lafève
A monoclonal antibody to platelet type III collagen-binding protein (TIIICBP) binds to blood and vascular cells, and inhibits platelet vessel-wall interactions.
Thrombosis and haemostasis 2001;86(2):694-701.
2001: Arnaud Bonnefoy; J Harsfalvi; G Pfliegler; Françoise Fauvel-Lafève; Chantal Legrand
The subendothelium of the HMEC-1 cell line supports thrombus formation in the absence of von Willebrand factor and collagen types I, III and VI.
Thrombosis and haemostasis 2001;85(3):552-9.
1999: LD Loganadane; Jany Vassy; Chantal Legrand; Françoise Fauvel-Lafeve
Transforming growth factor-beta 1 increases the adhesion of MDA-MB-231 mammary adenocarcinoma cells to the microvascular subendothelium.
Cell adhesion and communication 1999;7(1):57-71.
1999: N Berge; LD Loganadane; Jany Vassy; E Monnet; Chantal Legrand; Françoise Fauvel-Lafeve
Adhesion-induced intracellular signalling in endothelial cells depends on the nature of the matrix.
Cell adhesion and communication 1999;7(1):29-41.
1997: M Touhami; Françoise Fauvel-Lafève; Nicolas Da Silva; Christine Chomienne; Chantal Legrand
Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells.
Leukemia 1997;11(12):2137-42.
1997: Véronique Dubernard; Brigitte Arbeille; Monique Lemesle; Chantal Legrand
Evidence for an alpha-granular pool of the cytoskeletal protein alpha-actinin in human platelets that redistributes with the adhesive glycoprotein thrombospondin-1 during the exocytotic process.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):2293-305.
1997: LD Loganadane; N Berge; Chantal Legrand; Françoise Fauvel-Lafève
Endothelial cell proliferation regulated by cytokines modulates thrombospondin-1 secretion into the subendothelium.
Cytokine 1997;9(10):740-6.
1997: Chantal Legrand; Véronique Dubernard; S Rabhi-Sabile; V Morandi da Silva
Functional and clinical significance of thrombospondin.
Platelets 1997;8(4):211-23.
1996: F Incardona; J Lawler; D Cataldo; A Panet; Y Legrand; J M Foidart; Chantal Legrand
Heparin-binding domain, type 1 and type 2 repeats of thrombospondin mediate its interaction with human breast cancer cells.
Journal of cellular biochemistry 1996;62(4):431-42.
1996: S Rabhi-Sabile; Dominique Pidard; J Lawler; P Renesto; Michel Chignard; Chantal Legrand
Proteolysis of thrombospondin during cathepsin-G-induced platelet aggregation: functional role of the 165-kDa carboxy-terminal fragment.
FEBS letters 1996;386(1):82-6.
1995: V Thibert; Sylvia Bellucci; M Cristofari; Eliane Gluckman; Chantal Legrand
Increased platelet CD36 constitutes a common marker in myeloproliferative disorders.
British journal of haematology 1995;91(3):618-24.
1995: V Dubernard; D Faucher; Jean-Marie Launay; Chantal Legrand
Identification of the cytoskeletal protein alpha-actinin as a platelet thrombospondin-binding protein.
FEBS letters 1995;364(2):109-14.
1995: F Incardona; J M Lewalle; V Morandi; S Lambert; Y Legrand; J M Foidart; Chantal Legrand
Thrombospondin modulates human breast adenocarcinoma cell adhesion to human vascular endothelial cells.
Cancer research 1995;55(1):166-73.
1994: V Morandi; S E Cherradi; S Lambert; Françoise Fauvel-Lafève; Y Legrand; Chantal Legrand
Proinflammatory cytokines (interleukin-1 beta and tumor necrosis factor-alpha) down regulate synthesis and secretion of thrombospondin by human endothelial cells.
Journal of cellular physiology 1994;160(2):367-77.
1994: V Morandi; L Edelman; Y Legrand; Chantal Legrand
Characterization of a novel monoclonal antibody (V58A4) raised against a recombinant NH2-terminal heparin-binding fragment of human endothelial cell thrombospondin.
FEBS letters 1994;346(2-3):156-60.
1993: F Incardona; F Calvo; F Fauvel-Lafeve; Y Legrand; Chantal Legrand
Involvement of thrombospondin in the adherence of human breast-adenocarcinoma cells: a possible role in the metastatic process.
International journal of cancer. Journal international du cancer 1993;55(3):471-7.
1993: V Morandi; Françoise Fauvel-Lafeve; Chantal Legrand; Y Legrand
Role of thrombospondin in the adhesion of human endothelial cells in primary culture.
In vitro cellular & developmental biology. Animal 1993;29A(7):585-91.