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Y Legrand

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H Li; He Lu; Frank Griscelli; Paule Opolon; L Q Sun; Thierry Ragot; Y Legrand; D Belin; Jeannette Soria; Claudine Soria; Michel Perricaudet; Patrice Yeh
Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice.
Suzanne Menashi; M Dehem; I Souliac; Y Legrand; Rafael Fridman
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
Frederique Lindenmeyer; Y Legrand; Suzanne Menashi
Upregulation of MMP-9 expression in MDA-MB231 tumor cells by platelet granular membrane.

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All Publications

1998: H Li; He Lu; Frank Griscelli; Paule Opolon; L Q Sun; Thierry Ragot; Y Legrand; D Belin; Jeannette Soria; Claudine Soria; Michel Perricaudet; Patrice Yeh
Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice.
Gene therapy 1998;5(8):1105-13.
1998: Suzanne Menashi; M Dehem; I Souliac; Y Legrand; Rafael Fridman
Density-dependent regulation of cell-surface association of matrix metalloproteinase-2 (MMP-2) in breast-carcinoma cells.
International journal of cancer. Journal international du cancer 1998;75(2):259-65.
1997: Frederique Lindenmeyer; Y Legrand; Suzanne Menashi
Upregulation of MMP-9 expression in MDA-MB231 tumor cells by platelet granular membrane.
FEBS letters 1997;418(1-2):19-22.
1997: V Trochon; C Mabilat-Pragnon; P Bertrand; Y Legrand; Jeannette Soria; Claudine Soria; B Delpech; He Lu
Hyaluronectin blocks the stimulatory effect of hyaluronan-derived fragments on endothelial cells during angiogenesis in vitro.
FEBS letters 1997;418(1-2):6-10.
1997: C Mabilat-Pragnon; A Janin; L Michel; Annick Thomaïdis; Y Legrand; Claudine Soria; He Lu
Urokinase localization and activity in isolated eosinophils.
Thrombosis research 1997;88(4):373-9.
1997: B Baudin; M Berard; J L Carrier; Y Legrand; Ludovic Drouet
Vascular origin determines angiotensin I-converting enzyme expression in endothelial cells.
Endothelium : journal of endothelial cell research 1997;5(1):73-84.
1996: F Incardona; J Lawler; D Cataldo; A Panet; Y Legrand; J M Foidart; Chantal Legrand
Heparin-binding domain, type 1 and type 2 repeats of thrombospondin mediate its interaction with human breast cancer cells.
Journal of cellular biochemistry 1996;62(4):431-42.
1996: V Trochon; C Mabilat; P Bertrand; Y Legrand; F Smadja-Joffe; Claudine Soria; B Delpech; He Lu
Evidence of involvement of CD44 in endothelial cell proliferation, migration and angiogenesis in vitro.
International journal of cancer. Journal international du cancer 1996;66(5):664-8.
1996: Françoise Fauvel-Lafève; B Arbeille; christophe de romeuf; M Lemesle; Y Legrand
Heterogeneity of microfibrils: role of thrombospondin-microfibrils in the thrombogenicity of the subendothelium.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1996;319(4):333-41.
1996: He Lu; C Mabilat; Patrice Yeh; J D Guitton; H Li; M Pouchelet; D Shoevaert; Y Legrand; Jeannette Soria; Claudine Soria
Blockage of urokinase receptor reduces in vitro the motility and the deformability of endothelial cells.
FEBS letters 1996;380(1-2):21-4.
1995: Suzanne Menashi; I Vlodavsky; R Ishai-Michaeli; Y Legrand; Rafael Fridman
The extracellular matrix produced by bovine corneal endothelial cells contains progelatinase A.
FEBS letters 1995;361(1):61-4.
1995: C Belloc; He Lu; Claudine Soria; Rafael Fridman; Y Legrand; Suzanne Menashi
The effect of platelets on invasiveness and protease production of human mammary tumor cells.
International journal of cancer. Journal international du cancer 1995;60(3):413-7.
1995: F Incardona; J M Lewalle; V Morandi; S Lambert; Y Legrand; J M Foidart; Chantal Legrand
Thrombospondin modulates human breast adenocarcinoma cell adhesion to human vascular endothelial cells.
Cancer research 1995;55(1):166-73.
1994: He Lu; Patrice Yeh; J D Guitton; C Mabilat; F Desanlis; I Maury; Y Legrand; Jeannette Soria; Claudine Soria
Blockage of the urokinase receptor on the cell surface: construction and characterization of a hybrid protein consisting of the N-terminal fragment of human urokinase and human albumin.
FEBS letters 1994;356(1):56-9.
1994: G Flores-Delgado; W Hornebeck; Y Legrand; Suzanne Menashi
Fibrinolysis potentiating activity following endothelial cells-platelet interaction.
Thrombosis research 1994;76(3):245-52.
1994: Suzanne Menashi; Rafael Fridman; S Desrivieres; He Lu; Y Legrand; Claudine Soria
Regulation of 92-kDa gelatinase B activity in the extracellular matrix by tissue kallikrein.
Annals of the New York Academy of Sciences 1994;732():466-8.
1994: V Morandi; S E Cherradi; S Lambert; Françoise Fauvel-Lafève; Y Legrand; Chantal Legrand
Proinflammatory cytokines (interleukin-1 beta and tumor necrosis factor-alpha) down regulate synthesis and secretion of thrombospondin by human endothelial cells.
Journal of cellular physiology 1994;160(2):367-77.
1994: V Morandi; L Edelman; Y Legrand; Chantal Legrand
Characterization of a novel monoclonal antibody (V58A4) raised against a recombinant NH2-terminal heparin-binding fragment of human endothelial cell thrombospondin.
FEBS letters 1994;346(2-3):156-60.
1993: Sylvane Desrivieres; He Lu; N Peyri; Claudine Soria; Y Legrand; S Ménashi
Activation of the 92 kDa type IV collagenase by tissue kallikrein.
Journal of cellular physiology 1993;157(3):587-93.
1993: Françoise Fauvel-Lafève; V Tabaka; Jacques Caen; Y Legrand
Defective adhesion of blood platelets to vascular microfibrils in the Bernard-Soulier syndrome.
Blood 1993;82(7):1985-8.
1993: F Incardona; F Calvo; F Fauvel-Lafeve; Y Legrand; Chantal Legrand
Involvement of thrombospondin in the adherence of human breast-adenocarcinoma cells: a possible role in the metastatic process.
International journal of cancer. Journal international du cancer 1993;55(3):471-7.
1993: Suzanne Menashi; He Lu; Claudine Soria; Y Legrand
Endothelial cell proteases: physiological role and regulation.
Baillière's clinical haematology 1993;6(3):559-76.
1993: F Lafève; A Meric; B Arbeille; V Tabaka; Y Legrand
Spectrophotometric evaluation of the adhesion of blood platelets to collagen and microfibrils.
Thrombosis research 1993;71(3):193-204.
1993: V Morandi; Françoise Fauvel-Lafeve; Chantal Legrand; Y Legrand
Role of thrombospondin in the adhesion of human endothelial cells in primary culture.
In vitro cellular & developmental biology. Animal 1993;29A(7):585-91.
1992: Y Legrand; Françoise Fauvel-Lafève
Molecular mechanism of the interaction of subendothelial microfibrils with blood platelets.
Nouvelle revue française d'hématologie 1992;34(1):17-25.
1991: Bruno Baudin; A Tahraoui; F C Baumann; D Robic; Ludovic Drouet; Y Legrand
Purification and analysis of lung and plasma angiotensin I-converting enzyme by high-performance liquid chromatography.
Protein expression and purification 1991;2(5-6):412-9.
1991: Suzanne Menashi; L He; Claudine Soria; J Soria; A Thomaidis; Y Legrand
Modulation of endothelial cells fibrinolytic activity by platelets.
Thrombosis and haemostasis 1991;65(1):77-81.
1990: Suzanne Menashi; G Flores-Delgado; W Hornebeck; Y Legrand
[Endothelial cell proteases and their modulation by platelets].
Pathologie-biologie 1990;38(10):1015-9.
1990: Françoise Fauvel-Lafève; Y Legrand
Binding of plasma von Willebrand factor by arterial microfibrils.
Thrombosis and haemostasis 1990;64(1):145-9.
1990: A Karniguian; F Grelac; Sylviane Levy-Toledano; Y Legrand; Francine Rendu
Collagen-induced platelet activation mainly involves the protein kinase C pathway.
The Biochemical journal 1990;268(2):325-31.
1990: Suzanne Menashi; G Flores-Delgado; Y Legrand
Endothelial proteases stimulated by blood platelets.
Nouvelle revue française d'hématologie 1990;32(6):453-4.
1989: Suzanne Menashi; W Hornebeck; L Robert; J Caen; Y Legrand
Interaction of platelets with endothelial cells: activation of a novel neutral protease.
Experimental cell research 1989;183(2):294-302.
1989: Suzanne Menashi; W Hornebeck; L Robert; Y Legrand
Elastase-like activity in cultured aortic endothelial cells.
Thrombosis research 1989;53(1):11-8.
1988: Françoise Fauvel-Lafeve; P Picard; G Godeau; Y Legrand
Characterization of an antibody directed against a 128 kDa glycoprotein involved in the thrombogenicity of the elastin-associated microfibrils.
The Biochemical journal 1988;255(1):251-8.
1988: Bruno Baudin; P A Timmins; Ludovic Drouet; Y Legrand; F C Baumann
Molecular weight and shape of angiotensin-I converting enzyme. A neutron scattering study.
Biochemical and biophysical research communications 1988;154(3):1144-50.
1988: Françoise Fauvel-Lafeve; Y Legrand
Immunochemical identification of a thrombospondin-like structure in an arterial microfibrillar extract.
Thrombosis research 1988;50(2):305-16.
1987: A Karniguian; Francine Rendu; F Grelac; Marilyne Lebret; Y Legrand
Effect of a collagen-derived octapeptide on phosphoinositide turnover and 43K protein phosphorylation in collagen-activated platelets.
Biochemical and biophysical research communications 1987;146(1):277-83.
1986: Y Legrand; F Fauvel; B Arbeille; D Leger; H Mouhli; N Gutman; J P Muh
Activation of platelets by microfibrils and collagen. A comparative study.
Laboratory investigation; a journal of technical methods and pathology 1986;54(5):566-73.
1985: F Fauvel; A Karniguian; D Leger; G Pignaud; Y Legrand
Collagen induced platelet aggregation: a comparison between several commercially available collagens.
Thrombosis research 1985;38(6):707-11.
1985: D Pintigny; C Legrand; A Karniguian; Y Legrand; J P Caen
Evidence that a collagen derived octapeptide inhibits fibrinogen binding to platelets stimulated by collagen and not by ADP.
Biochemical and biophysical research communications 1985;128(2):547-53.
1985: E M Bevers; A Karniguian; Y Legrand; R F Zwaal
Collagen derived octapeptide inhibits platelet procoagulant activity induced by the combined action of collagen and thrombin.
Thrombosis research 1985;37(3):365-70.
1984: F Fauvel; R Campos-Oriola; D Leger; G Pignaud; Jean Rosenbaum; Y Legrand
Aortic endothelial cells in culture secrete glycoproteins reacting with blood platelets.
Biochemical and biophysical research communications 1984;123(1):114-20.
1984: W Hornebeck; G Pignaud; Y Legrand; L Robert
Differentiation of the elastase-type protease of platelets from other elastases.
Clinical physiology and biochemistry 1984;2(4):166-75.
1983: A Karniguian; Y Legrand; P Lefrancier; J P Caen
Effect of a collagen derived octapeptide on different steps of the platelet/collagen interaction.
Thrombosis research 1983;32(6):593-604.
1983: Y Legrand; A Karniguian; F Fauvel
[Collagen nonapeptide, a trap for platelets].
Presse médicale (Paris, France : 1983) 1983;12(37):2327-30.
1983: A Le Pape; N Gutman; J D Guitton; Y Legrand; J P Muh
Non enzymatic glycosylation increases platelet aggregating potency of collagen from placenta of diabetic human beings.
Biochemical and biophysical research communications 1983;111(2):602-10.
1983: F Fauvel; M E Grant; Y Legrand; H Souchon; G Tobelem; D S Jackson; J P Caen
Interaction of blood platelets with a microfibrillar extract from adult bovine aorta: requirement for von Willebrand factor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(2):551-4.
1983: Y Legrand; A Karniguian; F Fauvel; N Gutman
The molecular interaction between platelet and vascular wall.
Blood cells 1983;9(2):263-74.
1982: A Karniguian; P Simmons; Y Legrand; S Moncada; J P Caen
A comparison of the inhibitory effects of prostacyclin and carbacyclin on platelet adhesion to collagen.
Prostaglandins 1982;24(6):827-36.
1982: A Karniguian; Y Legrand; J P Caen
Prostaglandins: specific inhibition of platelet adhesion to collagen and relationship with cAMP level.
Prostaglandins 1982;23(4):437-57.
1982: Y Legrand; F Fauvel; N Gutman; A Karniguian; H Mouhli
[Thrombogenicity of the vessel: role of microfibrils and of collagen].
Nouvelle revue française d'hématologie 1982;24(3):163-6.
1982: P Birembaut; Y Legrand; J Bariety; R Bretton; F Fauvel; M F Belair; G Pignaud; J P Caen
Histochemical and ultrastructural characterization of subendothelial glycoprotein microfibrils interacting with platelets.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1982;30(1):75-80.
1981: L Drouet; Y Legrand; F Fauvel; P Birembaut
[Relation between the wall structure and modifications of the blood content (author's transl)].
Journal des maladies vasculaires 1981;6(1):13-5.
1981: Y Legrand; A Karniguian; F Fauvel
[The adhesion of blood platelets to collagen: molecular features of collagen (author's transl)].
Nouvelle revue française d'hématologie 1981;23(3):143-8.
1981: J L Wautier; Y Legrand; F Fauvel; J P Caen
Inhibition of platelet collagen interactions by the C1s subcomponent of the first component of the first component of complement.
Thrombosis research 1981;21(1-2):3-12.
1980: Y Legrand; A Karniguian; P Le Francier; F Fauvel; J P Caen
Evidence that a collagen-derived nonapeptide is a specific inhibitor of platelet-collagen interaction.
Biochemical and biophysical research communications 1980;96(4):1579-85.
1980: Y Legrand; F Fauvel; N Gutman; J P Muh; G Tobelem; H Souchon; A Karniguian; J P Caen
Microfibrils (MF) platelet interaction: requirement of von Willebrand factor.
Thrombosis research 1980;19(4-5):737-9.
1980: W Hornebeck; P M Starkey; J L Gordon; Y Legrand; G Pignaud; L Robert; J P Caen; H P Ehrlich; A J Barrett
The elastase-like enzyme of platelets.
Thrombosis and haemostasis 1980;42(5):1681-3.
1980: F Fauvel; Y Legrand
Inhibition of type III collagen induced platelet aggregation by active alpha 1 (III) CB4 peptide fragments.
Thrombosis research 1980;17(1-2):285-7.