FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Karla Lehle

Research Profile

Anatomy

Physiology

Cell Proliferation

Procedures

Chemicals & Drugs

Concepts & Ideas

Living Beings

Erythrina

Disorders

Type 2 Diabetes Mellitus

Co-author Network

Publications

TOP 3
Marietta von Suesskind-Schwendi; Thomas Puehler; Petra Ruemmele; Christof Schmid; Elisabeth Brunner; Claudius Diez; Stephan W Hirt; Karla Lehle
Suppression of bronchiolitis obliterans in allogeneic rat lung transplantation-Effectiveness of everolimus.
S W Hirt; T Puehler; Christof Schmid; M von Suesskind-Schwendi; Karla Lehle
Early administration of FTY720 prevents chronic airway as well as vascular destruction in experimental rat lung transplantation.
Karla Lehle; M Michl; C Schmid; M von Suesskind-Schwendi; HU Wottge; C Diez; E K Geissler; S W Hirt
Relevance of maintenance triple-drug immunosuppression to bridle the amplification of rat cytomegalovirus infection after experimental lung transplantation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Karla Lehle (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Marietta von Suesskind-Schwendi; Thomas Puehler; Petra Ruemmele; Christof Schmid; Elisabeth Brunner; Claudius Diez; Stephan W Hirt; Karla Lehle
Suppression of bronchiolitis obliterans in allogeneic rat lung transplantation-Effectiveness of everolimus.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2013;65(4):383-9.
2013: S W Hirt; T Puehler; Christof Schmid; M von Suesskind-Schwendi; Karla Lehle
Early administration of FTY720 prevents chronic airway as well as vascular destruction in experimental rat lung transplantation.
Transplantation proceedings 2013;45(2):783-6.
2012: Karla Lehle; M Michl; C Schmid; M von Suesskind-Schwendi; HU Wottge; C Diez; E K Geissler; S W Hirt
Relevance of maintenance triple-drug immunosuppression to bridle the amplification of rat cytomegalovirus infection after experimental lung transplantation.
Transplant infectious disease : an official journal of the Transplantation Society 2012;14(6):649-56.
2012: Marietta von Suesskind-Schwendi; Claudius Diez; Stephan W Hirt; Thomas Puehler; Petra Ruemmele; Christof Schmid; Karla Lehle
Impact of the severity of acute rejection in the early phase after rat lung transplantation on the effectiveness of mycophenolate mofetil to treat chronic allograft rejection.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2012;42(1):142-8.
2012: M von Süßkind-Schwendi; S W Hirt; Petra Ruemmele; C Schmid; Karla Lehle
Lung transplantation in the fischer 344-wistar kyoto strain combination is a relevant experimental model to study the development of bronchiolitis obliterans in the rat.
Experimental lung research 2012;38(3):111-23.
2011: Assad Haneya; Stephan W Hirt; Reinhard Kobuch; Thomas Metterlein; Alois Philipp; Thomas Puehler; Michael Ried; Christof Schmid; Claudius Diez; Karla Lehle
Coronary artery bypass grafting in patients with type 2 diabetes mellitus: a comparison between minimized and conventional extracorporeal circulation.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2011;57(6):501-6.
2011: Christoph W Eckermann; Karla Lehle; Stephan A Schmid; Denys N Wheatley; Leoni A Kunz-Schughart
Characterization and modulation of fibroblast/endothelial cell co-cultures for the in vitro preformation of three-dimensional tubular networks.
Cell biology international 2011;35(11):1097-110.
2011: Thomas Müller; Matthias Lubnow; Alois Philipp; Wulf Schneider-Brachert; Daniele Camboni; Christof Schmid; Karla Lehle
Risk of circuit infection in septic patients on extracorporeal membrane oxygenation: a preliminary study.
Artificial organs 2011;35(4):E84-90.
2010: Karla Lehle; Rainer H Straub; Henning Morawietz; Leoni A Kunz-Schughart
Relevance of disease- and organ-specific endothelial cells for in vitro research.
Cell biology international 2010;34(12):1231-8.
2010: Assad Haneya; Alois Philipp; Claudius Diez; Michael Ried; Thomas Puehler; Stephan Hirt; Reinhard Kobuch; Karla Lehle; Wolfgang Zink; Christof Schmid; York Zausig
Myocardial protection in patients undergoing coronary artery bypass grafting surgery using minimized extracorporeal circulation in combination with volatile anesthetic.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2010;56(6):532-7.
2010: T Puehler; A Haneya; Alois Philipp; D Camboni; S Hirt; W Zink; Karla Lehle; Leopold Rupprecht; Reinhard Kobuch; C Diez; Christof Schmid
Minimized extracorporeal circulation in coronary artery bypass surgery is equivalent to standard extracorporeal circulation in patients with reduced left ventricular function.
The Thoracic and cardiovascular surgeon 2010;58(4):204-9.
2010: Thomas Puehler; Otto Gleich; Simon Schopka; Leopold Rupprecht; Stephan Hirt; Christof Schmid; Karla Lehle
Impact of normothermic perfusion and protein supplementation on human endothelial cell function during organ preservation.
The Annals of thoracic surgery 2010;89(2):512-20.
2009: Assad Haneya; Alois Philipp; Claudius Diez; Michael Ried; Thomas Puehler; Daniele Camboni; York Zausig; Karla Lehle; Christof Schmid
Comparison of two different minimized extracorporeal circulation systems: hematological effects after coronary surgery.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2009;55(6):592-7.
2009: Karla Lehle; Martin Stock; Thomas Schmid; Simon Schopka; Rainer H Straub; Christof Schmid
Cell-type specific evaluation of biocompatibility of commercially available polyurethanes.
Journal of biomedical materials research. Part B, Applied biomaterials 2009;90(1):312-8.
2009: Simon Schopka; Franz-Xaver Schmid; Stephan Hirt; Dietrich E Birnbaum; Christof Schmid; Karla Lehle
Recellularization of biological heart valves with human vascular cells: in vitro hemocompatibility assessment.
Journal of biomedical materials research. Part B, Applied biomaterials 2009;88(1):130-8.
2008: Karla Lehle; Alois Philipp; Otto Gleich; Andreas Holzamer; Thomas Müller; Thomas Bein; Christof Schmid
Efficiency in extracorporeal membrane oxygenation-cellular deposits on polymethylpentene membranes increase resistance to blood flow and reduce gas exchange capacity.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2008;54(6):612-7.
2008: Fabian Stögbauer; Markus Neumeier; Johanna Weigert; Josef Wanninger; Margot Grandl; Karla Lehle; Gerd Schmitz; Charalampos Aslanidis; Andreas Schäffler; Jürgen Schölmerich; Christa Buechler
Highly efficient and low-cost method to isolate human blood monocytes with high purity.
Journal of immunological methods 2008;337(1):78-80.
2008: Bernhard Flörchinger; Alois Philipp; Alexander Klose; Michael Hilker; Reinhard Kobuch; Leopold Rupprecht; Andreas Keyser; Thomas Pühler; Stephan Hirt; Karsten Wiebe; Thomas Müller; Julia Langgartner; Karla Lehle; Christof Schmid
Pumpless extracorporeal lung assist: a 10-year institutional experience.
The Annals of thoracic surgery 2008;86(2):410-7; discussion 417.
2008: Karla Lehle; Stephan Schreml; Leoni A Kunz-Schughart; Leopold Rupprecht; Dietrich E Birnbaum; Christof Schmid; Jürgen G Preuner
mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells.
Journal of vascular research 2008;45(4):333-42.
2007: Karla Lehle; Gabriele I Kirchner; Leopold Rupprecht; M Gruber; Dietrich E Birnbaum; Franz X Schmid; Jürgen G Preuner
A prospective cross-over study comparing the pharmacokinetics of cyclosporine A and its metabolites after oral versus short-time intravenous cyclosporine A administration in pre-heart transplant patients.
Transplantation proceedings 2007;39(10):3323-8.
2007: Daniela Münzel; Karla Lehle; Frank Haubner; Christof Schmid; Dietrich E Birnbaum; Jürgen G Preuner
Impact of diabetic serum on endothelial cells: an in-vitro-analysis of endothelial dysfunction in diabetes mellitus type 2.
Biochemical and biophysical research communications 2007;362(2):238-44.
2007: Karla Lehle; Jürgen G Preuner; Anja Vogt; Leopold Rupprecht; Andreas Keyser; Reinhard Kobuch; Christof Schmid; Dietrich E Birnbaum
Endothelial cell dysfunction after coronary artery bypass grafting with extracorporeal circulation in patients with type 2 diabetes mellitus.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007;32(4):611-6.
2007: Karla Lehle; Leoni A Kunz-Schughart; Peter Kuhn; Stephan Schreml; Dietrich E Birnbaum; Jürgen G Preuner
Validity of a patient-derived system of tissue-specific human endothelial cells: interleukin-6 as a surrogate marker in the coronary system.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1721-8.
2007: Frank Haubner; Karla Lehle; Daniela Münzel; Christof Schmid; Dietrich E Birnbaum; Jürgen G Preuner
Hyperglycemia increases the levels of vascular cellular adhesion molecule-1 and monocyte-chemoattractant-protein-1 in the diabetic endothelial cell.
Biochemical and biophysical research communications 2007;360(3):560-5.
2007: Stephan Schreml; Karla Lehle; Dietrich E Birnbaum; Jürgen G Preuner
mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells.
International immunopharmacology 2007;7(6):781-90.
2007: Karla Lehle; Frank Haubner; Daniela Münzel; Dietrich E Birnbaum; Jürgen G Preuner
Development of a disease-specific model to evaluate endothelial dysfunction in patients with diabetes mellitus.
Biochemical and biophysical research communications 2007;357(1):308-13.
2007: Markus Hoenicka; Karla Lehle; Volker R Jacobs; Franz X Schmid; Dietrich E Birnbaum
Properties of the human umbilical vein as a living scaffold for a tissue-engineered vessel graft.
Tissue engineering 2007;13(1):219-29.
2006: Karla Lehle; Markus Hoenicka; Volker R Jacobs; Franz X Schmid; Dietrich E Birnbaum
Identification and reduction of cryoinjury in endothelial cells: a first step toward establishing a cell bank for vascular tissue engineering.
Tissue engineering 2006;12(12):3439-47.
2006: Dietrich E Birnbaum; Karla Lehle
CPB in high-risk groups: CPB in diabetics.
Perfusion 2006;21(4):235-8.
2006: Leoni A Kunz-Schughart; Josef A Schroeder; Marit Wondrak; Frank van Rey; Karla Lehle; Ferdinand Hofstaedter; Denys N Wheatley
Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro.
American journal of physiology. Cell physiology 2006;290(5):C1385-98.
2005: Volker R Jacobs; M Niemeyer; N Gottschalk; K T M Schneider; M Kiechle; Robert Oostendorp; C Peschel; M Hönicka; Karla Lehle; D Birnbaum; T P H Meyer; S Rapp; Jürgen Burkhart; Joachim Aigner; M Eblenkamp; Erich Wintermantel
[The STEMMAT-project as part of health initiative BayernAktiv: adult stem cells from umbilical cord and cord blood as alternative to embryonic stem cell research].
Zentralblatt für Gynäkologie 2005;127(6):368-72.
2005: Karla Lehle; Markus Hoenicka; Volker R Jacobs; Franz X Schmid; Dietrich E Birnbaum
Cryopreservation of human endothelial cells for vascular tissue engineering.
Cryobiology 2005;50(2):154-61.
2005: Karla Lehle; Dietrich E Birnbaum; Jürgen G Preuner
Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place.
Transplantation proceedings 2005;37(1):159-61.
2004: Karla Lehle; Stefan Lohn; G Günter Reinerth; Thomas Schubert; Jürgen G Preuner; Dietrich E Birnbaum
Cytological evaluation of the tissue-implant reaction associated with subcutaneous implantation of polymers coated with titaniumcarboxonitride in vivo.
Biomaterials 2004;25(24):5457-66.
2004: Franz X Schmid; Katrin Bielenberg; Stephan Holmer; Karla Lehle; Behrus Djavidani; Christopher Prasser; Christoph Wiesenack; Dietrich Birnbaum
Structural and biomolecular changes in aorta and pulmonary trunk of patients with aortic aneurysm and valve disease: implications for the Ross procedure.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2004;25(5):748-53.
2003: Karla Lehle; Johannes Buttstaedt; Dietrich E Birnbaum
Expression of adhesion molecules and cytokines in vitro by endothelial cells seeded on various polymer surfaces coated with titaniumcarboxonitride.
Journal of biomedical materials research. Part A 2003;65(3):393-401.
1998: Karla Lehle; Gabriele I Kirchner; KF Sewing; Leopold Rupprecht; Johannes Merk; Jürgen G Preuner
Intestinal metabolism of cyclosporine A in human heart transplant recipients.
Transplantation proceedings 1998;30(8):4044.
1998: Jürgen G Preuner; Karla Lehle; Andreas Keyser; Johannes Merk; Leopold Rupprecht; R Goebels
Development of severe adverse effects after discontinuing amiodarone therapy in human heart transplant recipients.
Transplantation proceedings 1998;30(8):3943-4.
1998: Jürgen G Preuner; Karla Lehle; H Eichinger; Leopold Rupprecht
First-pass metabolism of cyclosporine A in human intestine: inhibition by diltiazem.
Transplantation proceedings 1998;30(6):2545-6.
1998: T Minuth; B Krämer; Karla Lehle; Rainer Jaenicke; U Kohnert
The spectroscopic analysis, inhibition and binding studies demonstrate the equivalence of Erythrina caffra trypsin inhibitor and the recombinant substitution variant recSerETI.
Journal of biotechnology 1998;62(3):231-9.
1996: Karla Lehle; U Kohnert; A Stern; F Popp; Rainer Jaenicke
Effect of disulfide bonds on the structure, function, and stability of the trypsin/tPA inhibitor from Erythrina caffra: site-directed mutagenesis, expression, and physiochemical characterization.
Nature biotechnology 1996;14(4):476-80.
1994: Karla Lehle; A Wrba; Rainer Jaenicke
Erythrina caffra trypsin inhibitor retains its native structure and function after reducing its disulfide bonds.
Journal of molecular biology 1994;239(2):276-84.
1993: M Gross; Karla Lehle; Rainer Jaenicke; K H Nierhaus
Pressure-induced dissociation of ribosomes and elongation cycle intermediates. Stabilizing conditions and identification of the most sensitive functional state.
European journal of biochemistry / FEBS 1993;218(2):463-8.