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Brian Lehmann

Research Profile

Physiology

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William H Chappell; Brian D Lehmann; Linda Steelman; David M Terrian; Steven L Abrams; James A McCubrey
p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3.
Jackson R Taylor; Linda Steelman; Steven L Abrams; William H Chappell; Brian D Lehmann; James A McCubrey
Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.
Jitka A I Virag; Jessica L Dries; Peter R Easton; Amy M Friesland; Jon H DeAntonio; Vishnu Chintalgattu; Emily Cozzi; Brian D Lehmann; Jian M Ding; Robert M Lust
Attenuation of myocardial injury in mice with functional deletion of the circadian rhythm gene mPer2.

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2012: William H Chappell; Brian D Lehmann; Linda Steelman; David M Terrian; Steven L Abrams; James A McCubrey
p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3.
Cell cycle (Georgetown, Tex.) 2012;11(24):4579-88.
2011: Jackson R Taylor; Linda Steelman; Steven L Abrams; William H Chappell; Brian D Lehmann; James A McCubrey
Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.
Oncotarget 2011;2(8):610-26.
2010: Jitka A I Virag; Jessica L Dries; Peter R Easton; Amy M Friesland; Jon H DeAntonio; Vishnu Chintalgattu; Emily Cozzi; Brian D Lehmann; Jian M Ding; Robert M Lust
Attenuation of myocardial injury in mice with functional deletion of the circadian rhythm gene mPer2.
American journal of physiology. Heart and circulatory physiology 2010;298(3):H1088-95.
2008: Brian D Lehmann; Matthew S Paine; Adam M Brooks; James A McCubrey; Randall H Renegar; Rong Wang; David M Terrian
Senescence-associated exosome release from human prostate cancer cells.
Cancer research 2008;68(19):7864-71.
2008: John Lee; Brian D Lehmann; David M Terrian; William H Chappell; Franca Stivala; Massimo Libra; Alberto M Martelli; Linda Steelman; James A McCubrey
Targeting prostate cancer based on signal transduction and cell cycle pathways.
Cell cycle (Georgetown, Tex.) 2008;7(12):1745-62.
2008: Brian D Lehmann; James A McCubrey; Matthew S Paine; Adam M Brooks; William H Chappell; David M Terrian
Distinct roles for p107 and p130 in Rb-independent cellular senescence.
Cell cycle (Georgetown, Tex.) 2008;7(9):1262-8.
2008: James A McCubrey; Melissa L Sokolosky; Brian D Lehmann; Jackson R Taylor; Patrick M Navolanic; William H Chappell; Steven L Abrams; Kristin M Stadelman; Ellis W T Wong; Negin Misaghian; Stefan Horn; Jörg Bäsecke; Massimo Libra; Franca Stivala; Giovanni Ligresti; Agostino Tafuri; Michele Milella; Marek Zarzycki; Andrzej Dzugaj; Francesca Chiarini; Camilla Evangelisti; Alberto M Martelli; David M Terrian; Richard A Franklin; Linda Steelman
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.
Advances in enzyme regulation 2008;48():113-35.
2007: James A McCubrey; Linda Steelman; William H Chappell; Steven L Abrams; Ellis W T Wong; Fumin Chang; Brian D Lehmann; David M Terrian; Michele Milella; Agostino Tafuri; Franca Stivala; Massimo Libra; Jorg Basecke; Camilla Evangelisti; Alberto M Martelli; Richard A Franklin
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.
Biochimica et biophysica acta 2007;1773(8):1263-84.
2007: Brian D Lehmann; James A McCubrey; Holly S Jefferson; Matthew S Paine; William H Chappell; David M Terrian
A dominant role for p53-dependent cellular senescence in radiosensitization of human prostate cancer cells.
Cell cycle (Georgetown, Tex.) 2007;6(5):595-605.
2007: James A McCubrey; Linda Steelman; Richard A Franklin; Steven L Abrams; William H Chappell; Ellis W T Wong; Brian D Lehmann; David M Terrian; Jorg Basecke; Franca Stivala; Massimo Libra; Camilla Evangelisti; Alberto M Martelli
Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.
Advances in enzyme regulation 2007;47():64-103.