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Hans Lehrach

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Boris Greber; Hans Lehrach; Christian Regenbrecht
Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity.
Markus Ralser; Mirjam M Wamelink; Eduard A Struys; Christian Joppich; Sylvia Krobitsch; Cornelis Jakobs; Hans Lehrach
A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.
Andrew L Hufton; Detlef Groth; Martin Vingron; Hans Lehrach; Annemarie Poustka; Georgia Panopoulou
Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement.

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All Publications

2008: Boris Greber; Hans Lehrach; Christian Regenbrecht
Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity.
Stem cells and development 2008;17(6):1065-77.
2008: Markus Ralser; Mirjam M Wamelink; Eduard A Struys; Christian Joppich; Sylvia Krobitsch; Cornelis Jakobs; Hans Lehrach
A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(46):17807-11.
2008: Andrew L Hufton; Detlef Groth; Martin Vingron; Hans Lehrach; Annemarie Poustka; Georgia Panopoulou
Early vertebrate whole genome duplications were predated by a period of intense genome rearrangement.
Genome research 2008;18(10):1582-91.
2008: Ruben Rosenkranz; Tatiana Borodina; Hans Lehrach; Heinz Himmelbauer
Characterizing the mouse ES cell transcriptome with Illumina sequencing.
Genomics 2008;92(4):187-94.
2008: Martin Lange; Bogac Kaynak; Ulrike B Forster; Martje Tönjes; Jenny J. Fischer; Christina Grimm; Jenny Schlesinger; Steffen Just; Ilona Dunkel; Tammo Krueger; Siegrun Mebus; Hans Lehrach; Rudi Lurz; Johan Gobom; Wolfgang Rottbauer; Salim Abdelilah-Seyfried; Silke Sperling
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.
Genes & development 2008;22(17):2370-84.
2008: Marc Sultan; Marcel H Schulz; Hugues Richard; Alon Magen; Andreas Klingenhoff; Matthias Scherf; Martin Seifert; Tatjana Borodina; Aleksey Soldatov; Dmitri Parkhomchuk; Dominic Schmidt; Sean O'Keeffe; Stefan Haas; Martin Vingron; Hans Lehrach; Marie-Laure Yaspo
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome.
Science (New York, N.Y.) 2008;321(5891):956-60.
2008: Michael J Parsons; Christina H Grimm; Jose L Paya-Cano; Karen Sugden; Wilfried Nietfeld; Hans Lehrach; Leonard C Schalkwyk
Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function.
Mammalian genome : official journal of the International Mammalian Genome Society 2008;19(7-8):552-60.
2008: Christian Ra Regenbrecht; Marc Jung; Hans Lehrach; James Adjaye
The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines.
BMC medical genomics 2008;1():49.
2008: Markus Ralser; Almut Nebel; Rabea Kleindorp; Sylvia Krobitsch; Hans Lehrach; Stefan Schreiber; Richard Reinhardt; Bernd Timmermann
Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans.
BMC genetics 2008;9():38.
2008: Andrea Fiebitz; Lajos Nyarsik; Bernard Haendler; Yu-Hui Hu; Florian Wagner; Sabine Thamm; Hans Lehrach; Michal Janitz; Dominique Vanhecke
High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.
BMC genomics 2008;9():68.
2007: Christian Regenbrecht; Ralf Herwig; Thore C Brink; Doris Herrmann; Boris Greber; Smita Sudheer; Detlef Groth; Joseph W Carnwath; Hans Lehrach; Heiner Niemann
Conserved molecular portraits of bovine and human blastocysts as a consequence of the transition from maternal to embryonic control of gene expression.
Physiological genomics 2007;31(2):315-27.
2007: Christoph Wierling; Ralf Herwig; Hans Lehrach
Resources, standards and tools for systems biology.
Briefings in functional genomics & proteomics 2007;6(3):240-51.
2007: Gina Ziegler; Denise Harhausen; Claudia Schepers; Olaf Hoffmann; Christina Röhr; Vincent Prinz; Janett König; Hans Lehrach; Wilfried Nietfeld; george trendelenburg
TLR2 has a detrimental role in mouse transient focal cerebral ischemia.
Biochemical and biophysical research communications 2007;359(3):574-9.
2007: Andreas Dahl; Marc Sultan; Alexander Jung; Regine Schwartz; Matthias Lange; Michael Steinwand; Kenneth J Livak; Hans Lehrach; Lajos Nyarsik
Quantitative PCR based expression analysis on a nanoliter scale using polymer nano-well chips.
Biomedical microdevices 2007;9(3):307-14.
2007: Jian-Ping Liu; Mario Drungowski; Lajos Nyársik; Regine Schwartz; Hans Lehrach; Ralf Herwig; Michal Janitz
Oligonucleotide fingerprinting of arrayed genomic DNA sequences using LNA-modified hybridization probes.
Combinatorial chemistry & high throughput screening 2007;10(4):269-76.
2007: Antje Purmann; Joern Toedling; Markus Schueler; piero carninci; Hans Lehrach; Yoshihide Hayashizaki; Wolfgang Huber; Silke Sperling
Genomic organization of transcriptomes in mammals: Coregulation and cofunctionality.
Genomics 2007;89(5):580-7.
2007: James T Bennett; Katherine Joubin; Simon Cheng; Pia Aanstad; Ralf Herwig; Matthew Clark; Hans Lehrach; Alexander F Schier
Nodal signaling activates differentiation genes during zebrafish gastrulation.
Developmental biology 2007;304(2):525-40.
2007: Ute Nonhoff; Markus Ralser; Franziska Welzel; Ilaria Piccini; Daniela Balzereit; Marie-Laure Yaspo; Hans Lehrach; Sylvia Krobitsch
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules.
Molecular biology of the cell 2007;18(4):1385-96.
2007: Birgit Gerisch; Veerle Rottiers; Dongling Li; Daniel L Motola; Carolyn L Cummins; Hans Lehrach; David J Mangelsdorf; Adam Antebi
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5014-9.
2007: Yasmin Babaie; Ralf Herwig; Boris Greber; Thore C Brink; Wasco Wruck; Detlef Groth; Hans Lehrach; Tom Burdon; Christian Regenbrecht
Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells.
Stem cells (Dayton, Ohio) 2007;25(2):500-10.
2007: Boris Greber; Hans Lehrach; Christian Regenbrecht
Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
Stem cells (Dayton, Ohio) 2007;25(2):455-64.
2007: Marc Sultan; Ilaria Piccini; Daniela Balzereit; Ralf Herwig; Nidhi G Saran; Hans Lehrach; Roger H Reeves; Marie-Laure Yaspo
Gene expression variation in Down's syndrome mice allows prioritization of candidate genes.
Genome biology 2007;8(5):R91.
2007: Annemarie Poustka; Alexander Kühn; Detlef Groth; Vesna Weise; Shunsuke Yaguchi; Robert D Burke; Ralf Herwig; Hans Lehrach; Georgia Panopoulou
A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks.
Genome biology 2007;8(5):R85.
2007: Boris Greber; Hans Lehrach; Christian Regenbrecht
Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal.
BMC developmental biology 2007;7():46.
2007: Eckhard Nordhoff; Hans Lehrach
Identification and characterization of DNA-binding proteins by mass spectrometry.
Advances in biochemical engineering/biotechnology 2007;104():111-95.
2006: Hannah Müller; Marie-Laure Fogeron; Verena Lehmann; Hans Lehrach; Bodo M H Lange
A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint.
Science (New York, N.Y.) 2006;314(5799):654-7.
2006: Jian-Ping Liu; Anna Guerasimova; Regine Schwartz; Matthias Lange; Hans Lehrach; Lajos Nyársik; Michal Janitz
LNA-modified oligodeoxynucleotide hybridization with DNA microarrays printed on nanoporous membrane slides.
Combinatorial chemistry & high throughput screening 2006;9(8):591-7.
2006: Markus Ralser; Robert Querfurth; Hans-Jörg Warnatz; Hans Lehrach; Marie-Laure Yaspo; Sylvia Krobitsch
An efficient and economic enhancer mix for PCR.
Biochemical and biophysical research communications 2006;347(3):747-51.
2006: Evgenia Makrantonaki; Christian Regenbrecht; Ralf Herwig; Thore C Brink; Detlef Groth; Claus Hultschig; Hans Lehrach; Christos Zouboulis
Age-specific hormonal decline is accompanied by transcriptional changes in human sebocytes in vitro.
Aging cell 2006;5(4):331-44.
2006: Claudia Gebert; Christine Wrenzycki; Doris Herrmann; Daniela Gröger; Richard Reinhardt; Petra Hajkova; Andrea Lucas-Hahn; Joseph W Carnwath; Hans Lehrach; Heiner Niemann
The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA.
Genomics 2006;88(2):222-9.
2006: Pamela Kepper; Richard Reinhardt; Andreas Dahl; Hans Lehrach; Sascha Sauer
Matrix-assisted laser desorption/ionization mass spectrometric analysis of DNA on microarrays.
Clinical chemistry 2006;52(7):1303-10.
2006: Anna Guerasimova; Lajos Nyarsik; Jian-Ping Liu; Regine Schwartz; Matthias Lange; Hans Lehrach; Michal Janitz
Liquid-based hybridization assay with real-time detection in miniaturized array platforms.
Biomolecular engineering 2006;23(1):35-40.
2006: Axel Kowald; Hans Lehrach; Edda Klipp
Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase.
Journal of theoretical biology 2006;238(4):828-40.
2006: Claus Hultschig; Jürgen Kreutzberger; Harald Seitz; Zoltán Konthur; Konrad Büssow; Hans Lehrach
Recent advances of protein microarrays.
Current opinion in chemical biology 2006;10(1):4-10.
2006: Dieter Weichart; Johan Gobom; Sina Klopfleisch; Robert Häsler; Niklas Gustavsson; Susanne Billmann; Hans Lehrach; Dirk Seegert; Stefan Schreiber; Philip Rosenstiel
Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells.
The Journal of biological chemistry 2006;281(4):2380-9.
2006: Sascha Sauer; Richard Reinhardt; Hans Lehrach; Ivo Gut
Single-nucleotide polymorphisms: analysis by mass spectrometry.
Nature protocols 2006;1(4):1761-71.
2006: Markus Ralser; Gino Heeren; Michael Breitenbach; Hans Lehrach; Sylvia Krobitsch
Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes.
PloS one 2006;1():e30.
2006: Ralf Herwig; Hans Lehrach
Expression profiling of drug response--from genes to pathways.
Dialogues in clinical neuroscience 2006;8(3):283-93.
2006: Evgenia Makrantonaki; Christian Regenbrecht; Ralf Herwig; Thore C Brink; Detlef Groth; Claus Hultschig; Hans Lehrach; Christos Zouboulis
Aging of human sebocytes in vitro induced by exposure to a defined hormone environment.
Dermatology (Basel, Switzerland) 2006;213(3):262-3.
2006: Witold Eryk Wolski; Malcolm Farrow; Anne-Katrin Emde; Hans Lehrach; Maciej Lalowski; Knut Reinert
Analytical model of peptide mass cluster centres with applications.
Proteome science 2006;4():18.
2006: Yu-Hui Hu; Hans-Jörg Warnatz; Dominique Vanhecke; Florian Wagner; Andrea Fiebitz; Sabine Thamm; Pascal Kahlem; Hans Lehrach; Marie-Laure Yaspo; Michal Janitz
Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins.
BMC genomics 2006;7():155.
2006: Michal Janitz; Dominique Vanhecke; Hans Lehrach
High-throughput RNA interference in functional genomics.
Handbook of experimental pharmacology 2006;(173):97-104.
2006: Sabine Horn; Angelika Lueking; Derek Murphy; Alexander Staudt; Claudia Gutjahr; Kirsten Schulte; Andrea König; Martin Landsberger; Hans Lehrach; Stephan B Felix; David Gibson
Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip.
Proteomics 2006;6(2):605-13.
2006: Lotta Otterhag; Niklas Gustavsson; Magnus Alsterfjord; Christophe Pical; Hans Lehrach; Johan Gobom; Marianne Sommarin
Arabidopsis PDK1: identification of sites important for activity and downstream phosphorylation of S6 kinase.
Biochimie 2006;88(1):11-21.
2005: Sascha Sauer; Zoltán Konthur; Hans Lehrach
Genome projects and the functional-genomic era.
Combinatorial chemistry & high throughput screening 2005;8(8):659-67.
2005: Silke Sperling; Christina H Grimm; Ilona Dunkel; Siegrun Mebus; Hans-Peter Sperling; Arno Ebner; Raffaello Galli; Hans Lehrach; Christoph Fusch; Felix Berger; Stefanie Hammer
Identification and functional analysis of CITED2 mutations in patients with congenital heart defects.
Human mutation 2005;26(6):575-82.
2005: Y-H Hu; Dominique Vanhecke; Hans Lehrach; Michal Janitz
High-throughput subcellular protein localization using cell arrays.
Biochemical Society transactions 2005;33(Pt 6):1407-8.
2005: Ekaterina Mirgorodskaya; Erich E Wanker; Albrecht Otto; Hans Lehrach; Johan Gobom
Method for qualitative comparisons of protein mixtures based on enzyme-catalyzed stable-isotope incorporation.
Journal of proteome research 2005;4(6):2109-16.
2005: Christian Regenbrecht; John Huntriss; Ralf Herwig; Alia Benkahla; Thore C Brink; Christoph Wierling; Claus Hultschig; Detlef Groth; Marie-Laure Yaspo; Helen M Picton; Roger G Gosden; Hans Lehrach
Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells.
Stem cells (Dayton, Ohio) 2005;23(10):1514-25.
2005: Eleni Papakonstantinou; Alexios J Aletras; Evelyn Glass; Panagiotis Tsogas; Alexander Dionyssopoulos; Christian Regenbrecht; Sabine Fimmel; Panagiotis Gouvousis; Ralf Herwig; Hans Lehrach; Christos Zouboulis; George Karakiulakis
Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin.
The Journal of investigative dermatology 2005;125(4):673-84.
2005: Markus Ralser; Ute Nonhoff; Mario Albrecht; Thomas Lengauer; Erich E Wanker; Hans Lehrach; Sylvia Krobitsch
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.
Human molecular genetics 2005;14(19):2893-909.
2005: Tanja Feilner; Claus Hultschig; Justin Lee; Svenja Meyer; Richard Immink; Andrea Koenig; Alexandra Possling; Harald Seitz; Allan Beveridge; Dierk Scheel; Dolores J Cahill; Hans Lehrach; Jürgen Kreutzberger; Birgit Kersten
High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates.
Molecular & cellular proteomics : MCP 2005;4(10):1558-68.
2005: Ulrich Stelzl; Uwe Worm; Maciej Lalowski; Christian Haenig; Felix H Brembeck; Heike Goehler; Martin Stroedicke; Martina Zenkner; Anke Schoenherr; Susanne Koeppen; Jan Timm; Sascha Mintzlaff; Claudia Abraham; Nicole Bock; Silvia Kietzmann; Astrid Goedde; Engin Toksöz; Anja Droege; Sylvia Krobitsch; Bernhard Korn; Walter Birchmeier; Hans Lehrach; Erich E Wanker
A human protein-protein interaction network: a resource for annotating the proteome.
Cell 2005;122(6):957-68.
2005: Dörte Gade; Dorothea Theiss; Daniela Lange; Ekaterina Mirgorodskaya; Thierry Lombardot; Frank Oliver Glöckner; Michael Kube; Richard Reinhardt; Rudolf Amann; Hans Lehrach; Ralf Rabus; Johan Gobom
Towards the proteome of the marine bacterium Rhodopirellula baltica: mapping the soluble proteins.
Proteomics 2005;5(14):3654-71.
2005: Vera Jankowski; Raymond Vanholder; Markus van der Giet; Lars Henning; Markus Tölle; Gilbert Schönfelder; Anja Krakow; Sevil Karadogan; Niklas Gustavsson; Johan Gobom; Jessie Webb; Hans Lehrach; Günter Giebing; Hartmut Schlüter; Karl F Hilgers; Walter Zidek; Joachim Jankowski
Detection of angiotensin II in supernatants of stimulated mononuclear leukocytes by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass analysis.
Hypertension 2005;46(3):591-7.
2005: Niklas Gustavsson; Boris Greber; Thomas Kreitler; Heinz Himmelbauer; Hans Lehrach; Johan Gobom
A proteomic method for the analysis of changes in protein concentrations in response to systemic perturbations using metabolic incorporation of stable isotopes and mass spectrometry.
Proteomics 2005;5(14):3563-70.
2005: Angelika Lueking; Otmar Huber; Christopher Wirths; Kirsten Schulte; Karola M Stieler; Ulrike Blume-Peytavi; Axel Kowald; Karin Hensel-Wiegel; Rudolf Tauber; Hans Lehrach; Helmut E Meyer; David Gibson
Profiling of alopecia areata autoantigens based on protein microarray technology.
Molecular & cellular proteomics : MCP 2005;4(9):1382-90.
2005: Markus Ralser; Heike Goehler; Erich E Wanker; Hans Lehrach; Sylvia Krobitsch
Generation of a yeast two-hybrid strain suitable for competitive protein binding analysis.
BioTechniques 2005;39(2):165-6, 168.
2005: Christine M Costello; Nancy Mah; Robert Häsler; Philip Rosenstiel; Georg H Waetzig; Andreas Hahn; Timothy Lu; Yesim Gurbuz; Susanna Nikolaus; Mario Albrecht; Jochen Hampe; Ralph Lucius; Günther Klöppel; Holger Eickhoff; Hans Lehrach; Thomas Lengauer; Stefan Schreiber
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays.
PLoS medicine 2005;2(8):e199.
2005: Konrad Büssow; Christoph Scheich; Volker Sievert; Ulrich Harttig; Jörg Schultz; Bernd Simon; Peer Bork; Hans Lehrach; Udo Heinemann
Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones.
Microbial cell factories 2005;4():21.
2005: Lukas Bürkle; Svenja Meyer; Hakan Dortay; Hans Lehrach; Alexander Heyl
In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system.
Functional & integrative genomics 2005;5(3):175-83.
2005: Ewan Birney; Andrea Ciliberto; Morten Colding-Jørgensen; Albert Goldbeter; Stefan Hohmann; Martin Kuiper; Hans Lehrach; Gisela Miczka; Erik Mosekilde; Hans Westerhoff; Olaf Wolkenhauer
Report of an EU projects workshop on systems biology held in Brussels, Belgium on 8 December 2004.
Systems biology 2005;152(2):55-60.
2005: Sascha Sauer; Bodo M H Lange; Johan Gobom; Lajos Nyarsik; Harald Seitz; Hans Lehrach
Miniaturization in functional genomics and proteomics.
Nature reviews. Genetics 2005;6(6):465-76.
2005: Sigrid Steller; Philipp Angenendt; David Gibson; Sigrid Heuberger; Hans Lehrach; Jürgen Kreutzberger
Bacterial protein microarrays for identification of new potential diagnostic markers for Neisseria meningitidis infections.
Proteomics 2005;5(8):2048-55.
2005: Boris Greber; Helena Tandara; Hans Lehrach; Heinz Himmelbauer
Comparison of PCR-based mutation detection methods and application for identification of mouse Sult1a1 mutant embryonic stem cell clones using pooled templates.
Human mutation 2005;25(5):483-90.
2005: Boris Greber; Hans Lehrach; Heinz Himmelbauer
Mouse splice mutant generation from ENU-treated ES cells--a gene-driven approach.
Genomics 2005;85(5):557-62.
2005: Patrick Giavalisco; Eckhard Nordhoff; Thomas Kreitler; Klaus-Dieter Klöppel; Hans Lehrach; Joachim Klose; Johan Gobom
Proteome analysis of Arabidopsis thaliana by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation-time of flight mass spectrometry.
Proteomics 2005;5(7):1902-13.
2005: Patrick Giavalisco; Daniel Wilson; Thomas Kreitler; Hans Lehrach; Joachim Klose; Johan Gobom; Paola Fucini
High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome.
Plant molecular biology 2005;57(4):577-91.
2005: Claudia Gutjahr; Derek Murphy; Angelika Lueking; Andrea Koenig; Michal Janitz; John O'Brien; Bernhard Korn; Sabine Horn; Hans Lehrach; Dolores J Cahill
Mouse protein arrays from a TH1 cell cDNA library for antibody screening and serum profiling.
Genomics 2005;85(3):285-96.
2005: Markus Ralser; Mario Albrecht; Ute Nonhoff; Thomas Lengauer; Hans Lehrach; Sylvia Krobitsch
An integrative approach to gain insights into the cellular function of human ataxin-2.
Journal of molecular biology 2005;346(1):203-14.
2005: Philipp Angenendt; Hans Lehrach; Jürgen Kreutzberger; Jörn Glökler
Subnanoliter enzymatic assays on microarrays.
Proteomics 2005;5(2):420-5.
2005: Ekaterina Mirgorodskaya; Corina Braeuer; Paola Fucini; Hans Lehrach; Johan Gobom
Nanoflow liquid chromatography coupled to matrix-assisted laser desorption/ionization mass spectrometry: sample preparation, data analysis, and application to the analysis of complex peptide mixtures.
Proteomics 2005;5(2):399-408.
2005: Witold Eryk Wolski; Maciej Lalowski; Peter Martus; Ralf Herwig; Patrick Giavalisco; Johan Gobom; Albert Sickmann; Hans Lehrach; Knut Reinert
Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process.
BMC bioinformatics 2005;6():285.
2004: J Illiger; Ralf Herwig; Matthias Steinfath; T Przewieslik; Thorsten Elge; Ch Bull; Uwe Radelof; Hans Lehrach; Michal Janitz
Establishment of T cell-specific and natural killer cell-specific unigene sets: towards high-throughput genomics of leukaemia.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2004;31(6):253-7.
2004: Jean-Nicolas Volff; Hans Lehrach; Richard Reinhardt; Daniel Chourrout
Retroelement dynamics and a novel type of chordate retrovirus-like element in the miniature genome of the tunicate Oikopleura dioica.
Molecular biology and evolution 2004;21(11):2022-33.
2004: Christian Regenbrecht; Ralf Herwig; Doris Herrmann; Wasco Wruck; Alia Benkahla; Thore C Brink; Monika Nowak; Joseph W Carnwath; Claus Hultschig; Heiner Niemann; Hans Lehrach
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays.
BMC genomics 2004;5():83.
2004: Dominik Seelow; Raffaello Galli; Siegrun Mebus; Hans-Peter Sperling; Hans Lehrach; Silke Sperling
d-matrix - database exploration, visualization and analysis.
BMC bioinformatics 2004;5():168.
2004: Tatiana A Borodina; Hans Lehrach; Aleksey V Soldatov
Ligation detection reaction-TaqMan procedure for single nucleotide polymorphism detection on genomic DNA.
Analytical biochemistry 2004;333(2):309-19.
2004: Rolf B Edvardsen; Emmanuelle Lerat; Anne Dorthea Maeland; Mette Flåt; Rita Tewari; Marit F Jensen; Hans Lehrach; Richard Reinhardt; Hee-Chan Seo; Daniel Chourrout
Hypervariable and highly divergent intron-exon organizations in the chordate Oikopleura dioica.
Journal of molecular evolution 2004;59(4):448-57.
2004: Heike Goehler; Maciej Lalowski; Ulrich Stelzl; Stephanie Waelter; Martin Stroedicke; Uwe Worm; Anja Droege; Katrin S Lindenberg; Maria Knoblich; Christian Haenig; Martin Herbst; Jaana Suopanki; Eberhard Scherzinger; Claudia Abraham; Bianca Bauer; Renate Hasenbank; Anja Fritzsche; Andreas H Ludewig; Konrad Büssow; Konrad Buessow; Sarah H Coleman; Claire-Anne Gutekunst; Bernhard G Landwehrmeyer; Hans Lehrach; Erich E Wanker
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
Molecular cell 2004;15(6):853-65.
2004: Sascha Sauer; Pamela Kepper; Anett Smyra; Andreas Dahl; Falk-Thilo Ferse; Hans Lehrach; Richard Reinhardt
Automated solid-phase extraction for purification of single nucleotide polymorphism genotyping products prior to matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis.
Journal of chromatography. A 2004;1049(1-2):9-16.
2004: Hee-Chan Seo; Rolf B Edvardsen; Anne Dorthea Maeland; Marianne Bjordal; Marit F Jensen; Anette Hansen; Mette Flaat; Jean Weissenbach; Hans Lehrach; Patrick Wincker; Richard Reinhardt; Daniel Chourrout
Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica.
Nature 2004;431(7004):67-71.
2004: Andreas M Rickert; Hans Lehrach; Silke Sperling
Multiplexed real-time PCR using universal reporters.
Clinical chemistry 2004;50(9):1680-3.
2004: Andreas M Rickert; Tatiana A Borodina; Eckehard J Kuhn; Hans Lehrach; Silke Sperling
Refinement of single-nucleotide polymorphism genotyping methods on human genomic DNA: amplifluor allele-specific polymerase chain reaction versus ligation detection reaction-TaqMan.
Analytical biochemistry 2004;330(2):288-97.
2004: Pascal Kahlem; Marc Sultan; Ralf Herwig; Matthias Steinfath; Daniela Balzereit; Barbara Eppens; Nidhi G Saran; Mathew Pletcher; Sarah T South; Gail Stetten; Hans Lehrach; Roger H Reeves; Marie-Laure Yaspo
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome.
Genome research 2004;14(7):1258-67.
2004: Annemarie Poustka; Alexander Kühn; Vesna Radosavljevic; Ruth Wellenreuther; Hans Lehrach; Georgia Panopoulou
On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo.
Evolution & development 2004;6(4):227-36.
2004: Detlef Groth; Hans Lehrach; Steffen Hennig
GOblet: a platform for Gene Ontology annotation of anonymous sequence data.
Nucleic acids research 2004;32(Web Server issue):W313-7.
2004: Rebecca Quiring; Beate Wittbrodt; Thorsten Henrich; Mirana Ramialison; Carola Burgtorf; Hans Lehrach; Joachim Wittbrodt
Large-scale expression screening by automated whole-mount in situ hybridization.
Mechanisms of development 2004;121(7-8):971-6.
2004: Maryam Zadeh Khorasani; Steffen Hennig; Gabriele Imre; Shuichi Asakawa; Stefanie Palczewski; Anja Berger; Hiroshi Hori; Kiyoshi Naruse; Hiroshi Mitani; Akihiro Shima; Hans Lehrach; Joachim Wittbrodt; Hisato Kondoh; Nobuyoshi Shimizu; Heinz Himmelbauer
A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing.
Mechanisms of development 2004;121(7-8):903-13.
2004: Philipp Angenendt; Jeannine Wilde; Gregor Kijanka; Sabine Baars; Dolores J Cahill; Jürgen Kreutzberger; Hans Lehrach; Zoltán Konthur; Jörn Glökler
Seeing better through a MIST: evaluation of monoclonal recombinant antibody fragments on microarrays.
Analytical chemistry 2004;76(10):2916-21.
2004: Peter Hurt; Lutz Walter; Ralf Sudbrak; Sven Klages; Ines Müller; Takashi Shiina; Hidetoshi Inoko; Hans Lehrach; Eberhard Günther; Richard Reinhardt; Heinz Himmelbauer
The genomic sequence and comparative analysis of the rat major histocompatibility complex.
Genome research 2004;14(4):631-9.
2004: Philipp Angenendt; Lajos Nyarsik; Witold Szaflarski; Jörn Glökler; Knud H Nierhaus; Hans Lehrach; Dolores J Cahill; Angelika Lueking
Cell-free protein expression and functional assay in nanowell chip format.
Analytical chemistry 2004;76(7):1844-9.
2004: Nancy Mah; Anders Thelin; Timothy Lu; Susanna Nikolaus; Tanja Kühbacher; Yesim Gurbuz; Holger Eickhoff; Günther Klöppel; Hans Lehrach; Björn Mellgård; Christine M Costello; Stefan Schreiber
A comparison of oligonucleotide and cDNA-based microarray systems.
Physiological genomics 2004;16(3):361-70.
2004: Konrad Büssow; Claudia Quedenau; Volker Sievert; Janett Tischer; Christoph Scheich; Harald Seitz; Brigitte Hieke; Frank H Niesen; Frank Götz; Ulrich Harttig; Hans Lehrach
A catalog of human cDNA expression clones and its application to structural genomics.
Genome biology 2004;5(9):R71.
2004: Oliver Bauer; Anna Guerasimova; Sascha Sauer; Sabine Thamm; Matthias Steinfath; Ralf Herwig; Michal Janitz; Hans Lehrach; Uwe Radelof
Multiplexed hybridizations of positively charge-tagged peptide nucleic acids detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Rapid communications in mass spectrometry : RCM 2004;18(16):1821-9.
2004: Christian M T Spahn; Hans Lehrach; Peter Jungblut
A European focus on proteomics.
Genome biology 2004;5(5):322.
2003: Margret R Hoehe; Bernd Timmermann; Hans Lehrach
Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics.
Current pharmaceutical biotechnology 2003;4(6):351-78.
2003: Annemarie Poustka; Detlef Groth; Steffen Hennig; Sabine Thamm; Andrew Cameron; Alfred Beck; Richard Reinhardt; Ralf Herwig; Georgia Panopoulou; Hans Lehrach
Generation, annotation, evolutionary analysis, and database integration of 20,000 unique sea urchin EST clusters.
Genome research 2003;13(12):2736-46.
2003: Carola Burgtorf; Pamela Kepper; Margret R Hoehe; Carsten Schmitt; Richard Reinhardt; Hans Lehrach; Sascha Sauer
Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes.
Genome research 2003;13(12):2717-24.
2003: Angelika Lueking; Alexandra Possling; Otmar Huber; Allan Beveridge; Martin Horn; Holger Eickhoff; Johannes Schuchardt; Hans Lehrach; Dolores J Cahill
A nonredundant human protein chip for antibody screening and serum profiling.
Molecular & cellular proteomics : MCP 2003;2(12):1342-9.
2003: Anne Busch; Sabine Engemann; Rudi Lurz; hitoshi okazawa; Hans Lehrach; Erich E Wanker
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.
The Journal of biological chemistry 2003;278(42):41452-61.
2003: Tatiana A Borodina; Hans Lehrach; Aleksey V Soldatov
DNA purification on homemade silica spin-columns.
Analytical biochemistry 2003;321(1):135-7.
2003: Philipp Angenendt; Jörn Glökler; Zoltán Konthur; Hans Lehrach; Dolores J Cahill
3D protein microarrays: performing multiplex immunoassays on a single chip.
Analytical chemistry 2003;75(17):4368-72.
2003: Philipp Angenendt; Jörn Glökler; Jens Sobek; Hans Lehrach; Dolores J Cahill
Next generation of protein microarray support materials: evaluation for protein and antibody microarray applications.
Journal of chromatography. A 2003;1009(1-2):97-104.
2003: Rafal Grzeskowiak; Henning Witt; Mario Drungowski; Rolf Thermann; Steffen Hennig; Andreas Perrot; Karl Josef Osterziel; Dirk Klingbiel; Stefanie Scheid; Rainer Spang; Hans Lehrach; Patricia Ruiz
Expression profiling of human idiopathic dilated cardiomyopathy.
Cardiovascular research 2003;59(2):400-11.
2003: Tatiana A Borodina; Hans Lehrach; Aleksey V Soldatov
Ligation-based synthesis of oligonucleotides with block structure.
Analytical biochemistry 2003;318(2):309-13.
2003: Birgit Kersten; Tanja Feilner; A Kramer; S Wehrmeyer; Alexandra Possling; Isabell Witt; María-Inés Zanor; R Stracke; Angelika Lueking; Jürgen Kreutzberger; Hans Lehrach; D J Cahilll
Generation of Arabidopsis protein chips for antibody and serum screening.
Plant molecular biology 2003;52(5):999-1010.
2003: Steffen Hennig; Detlef Groth; Hans Lehrach
Automated Gene Ontology annotation for anonymous sequence data.
Nucleic acids research 2003;31(13):3712-5.
2003: Georgia Panopoulou; Steffen Hennig; Detlef Groth; Antje Krause; Annemarie Poustka; Ralf Herwig; Martin Vingron; Hans Lehrach
New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes.
Genome research 2003;13(6A):1056-66.
2003: Sascha Sauer; Hans Lehrach; Richard Reinhardt
MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging.
Nucleic acids research 2003;31(11):e63.
2003: Bogac Kaynak; Anja von Heydebreck; Siegrun Mebus; Dominik Seelow; Steffen Hennig; Jan Vogel; Hans-Peter Sperling; Reinhard Pregla; Vladimir Alexi-Meskishvili; Roland Hetzer; Peter E Lange; Martin Vingron; Hans Lehrach; Silke Sperling
Genome-wide array analysis of normal and malformed human hearts.
Circulation 2003;107(19):2467-74.
2003: Boris Greber; Hans Lehrach; Heinz Himmelbauer
Characterization of trimethylpsoralen as a mutagen for mouse embryonic stem cells.
Mutation research 2003;525(1-2):67-76.
2003: Rimantas Kodzius; Claudio Rhyner; Zoltán Konthur; Donald Buczek; Hans Lehrach; Gerald Walter; Reto Crameri
Rapid identification of allergen-encoding cDNA clones by phage display and high-density arrays.
Combinatorial chemistry & high throughput screening 2003;6(2):147-54.
2003: Barbora Malecova; Juliane Ramser; John K O'Brien; Michal Janitz; Jana Júdová; Hans Lehrach; Jozef Simúth
Honeybee (Apis mellifera L.) mrjp gene family: computational analysis of putative promoters and genomic structure of mrjp1, the gene coding for the most abundant protein of larval food.
Gene 2003;303():165-75.
2003: Patrick Giavalisco; Eckhard Nordhoff; Hans Lehrach; Johan Gobom; Joachim Klose
Extraction of proteins from plant tissues for two-dimensional electrophoresis analysis.
Electrophoresis 2003;24(1-2):207-16.
2003: Ralf Sudbrak; Richard Reinhardt; Steffen Hennig; Hans Lehrach; Eberhard Günther; Lutz Walter
Comparative and evolutionary analysis of the rhesus macaque extended MHC class II region.
Immunogenetics 2003;54(10):699-704.
2003: Angelika Lueking; Sabine Horn; Hans Lehrach; Dolores J Cahill
A dual-expression vector allowing expression in E. coli and P. pastoris, including new modifications.
Methods in molecular biology (Clifton, N.J.) 2003;205():31-42.
2002: Volker Heiser; Sabine Engemann; Wolfgang Bröcker; Ilona Dunkel; Annett Boeddrich; Stephanie Waelter; Eckhard Nordhoff; Rudi Lurz; Nancy Schugardt; Susanne Rautenberg; Christian Herhaus; Gerhard Barnickel; Henning Böttcher; Hans Lehrach; Erich E Wanker
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Proceedings of the National Academy of Sciences of the United States of America 2002;99 Suppl 4():16400-6.
2002: Yorick Gitton; Nadia Dahmane; Sonya Baik; Ariel Ruiz i Altaba; Lorenz Neidhardt; Manuela Scholze; Bernhard G Herrmann; Pascal Kahlem; Alia Benkahla; Sabine Schrinner; Reha Yildirimman; Ralf Herwig; Hans Lehrach; Marie-Laure Yaspo
A gene expression map of human chromosome 21 orthologues in the mouse.
Nature 2002;420(6915):586-90.
2002: Ralf Herwig; Britta Schulz; Bernd Weisshaar; Steffen Hennig; Matthias Steinfath; Mario Drungowski; Dietmar Stahl; Wasco Wruck; Andreas Menze; John O'Brien; Hans Lehrach; Uwe Radelof
Construction of a 'unigene' cDNA clone set by oligonucleotide fingerprinting allows access to 25 000 potential sugar beet genes.
The Plant journal : for cell and molecular biology 2002;32(5):845-57.
2002: Christoph Wierling; Matthias Steinfath; Thorsten Elge; Steffen Schulze-Kremer; Pia Aanstad; Matthew Clark; Hans Lehrach; Ralf Herwig
Simulation of DNA array hybridization experiments and evaluation of critical parameters during subsequent image and data analysis.
BMC bioinformatics 2002;3():29.
2002: Philipp Angenendt; Jörn Glökler; Derek Murphy; Hans Lehrach; Dolores J Cahill
Toward optimized antibody microarrays: a comparison of current microarray support materials.
Analytical biochemistry 2002;309(2):253-60.
2002: Tania Fuchs; Barbora Malecova; Chaim Linhart; Roded Sharan; Miriam Khen; Ralf Herwig; Dmitry Shmulevich; Ran Elkon; Matthias Steinfath; John K O'Brien; Uwe Radelof; Hans Lehrach; Doron Lancet; Ron Shamir
DEFOG: a practical scheme for deciphering families of genes.
Genomics 2002;80(3):295-302.
2002: Johan Gobom; Martin Mueller; Volker Egelhofer; Dorothea Theiss; Hans Lehrach; Eckhard Nordhoff
A calibration method that simplifies and improves accurate determination of peptide molecular masses by MALDI-TOF MS.
Analytical chemistry 2002;74(15):3915-23.
2002: Wasco Wruck; Huw Griffiths; Matthias Steinfath; Hans Lehrach; Uwe Radelof; John O'Brien
Xdigitise: visualization of hybridization experiments.
Bioinformatics (Oxford, England) 2002;18(5):757-60.
2002: Volker Egelhofer; Johan Gobom; Harald Seitz; Patrick Giavalisco; Hans Lehrach; Eckhard Nordhoff
Protein identification by MALDI-TOF-MS peptide mapping: a new strategy.
Analytical chemistry 2002;74(8):1760-71.
2002: Joachim Klose; Christina Nock; Marion Herrmann; Kai Stühler; Katrin Marcus; Martin Blüggel; Eberhard Krause; Leonard C Schalkwyk; Sohaila Rastan; Steve D M Brown; Konrad Büssow; Heinz Himmelbauer; Hans Lehrach
Genetic analysis of the mouse brain proteome.
Nature genetics 2002;30(4):385-93.
2002: Frank Schmidt; Angelika Lueking; Eckhard Nordhoff; Johan Gobom; Joachim Klose; Harald Seitz; Volker Egelhofer; Holger Eickhoff; Hans Lehrach; Dolores J Cahill
Generation of minimal protein identifiers of proteins from two-dimensional gels and recombinant proteins.
Electrophoresis 2002;23(4):621-5.
2002: Heike Olbrich; Karsten Häffner; Andreas Kispert; Alexander Völkel; Andreas Volz; Gürsel Sasmaz; Richard Reinhardt; Steffen Hennig; Hans Lehrach; Nikolaus Konietzko; Maimoona A Zariwala; Peadar G Noone; Michael Knowles; Hannah M Mitchison; Maggie Meeks; Eddie M K Chung; Friedhelm Hildebrandt; Ralf Sudbrak; Heymut Omran
Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry.
Nature genetics 2002;30(2):143-4.
2002: Asao Fujiyama; Hidemi Watanabe; Atsushi Toyoda; Todd D Taylor; Takehiko Itoh; Shih-Feng Tsai; Hong-Seog Park; Marie-Laure Yaspo; Hans Lehrach; Zhu Chen; Gang Fu; Naruya Saitou; Kazutoyo Osoegawa; Pieter J de Jong; Yumiko Suto; Masahira Hattori; Yoshiyuki Sakaki
Construction and analysis of a human-chimpanzee comparative clone map.
Science (New York, N.Y.) 2002;295(5552):131-4.
2002: Holger Eickhoff; Zoltán Konthur; Angelika Lueking; Hans Lehrach; Gerald Walter; Eckhard Nordhoff; Lajos Nyarsik; Konrad Büssow
Protein array technology: the tool to bridge genomics and proteomics.
Advances in biochemical engineering/biotechnology 2002;77():103-12.
2001: Hee-Chan Seo; M Kube; Rolf B Edvardsen; Marit F Jensen; A Beck; E Spriet; G Gorsky; Eric M Thompson; Hans Lehrach; Richard Reinhardt; Daniel Chourrout
Miniature genome in the marine chordate Oikopleura dioica.
Science (New York, N.Y.) 2001;294(5551):2506.
2001: Thomas Dickmeis; Pia Aanstad; Matthew Clark; Nadine Fischer; Ralf Herwig; Philippe Mourrain; Patrick Blader; Frédéric M Rosa; Hans Lehrach; Uwe Strähle
Identification of nodal signaling targets by array analysis of induced complex probes.
Developmental dynamics : an official publication of the American Association of Anatomists 2001;222(4):571-80.
2001: Leonard C Schalkwyk; Brian Cusack; I Dunkel; M Hopp; M Kramer; S Palczewski; J Piefke; S Scheel; M Weiher; G Wenske; Hans Lehrach; Heinz Himmelbauer
Advanced integrated mouse YAC map including BAC framework.
Genome research 2001;11(12):2142-50.
2001: Ralf Herwig; Pia Aanstad; Matthew Clark; Hans Lehrach
Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments.
Nucleic acids research 2001;29(23):E117.
2001: Caterina Holz; Angelika Lueking; L Bovekamp; Claudia Gutjahr; Natalia Bolotina; Hans Lehrach; Dolores J Cahill
A human cDNA expression library in yeast enriched for open reading frames.
Genome research 2001;11(10):1730-5.
2001: Anna Guerasimova; Lajos Nyarsik; I Girnus; Matthias Steinfath; Wasco Wruck; H Griffiths; Ralf Herwig; Christoph Wierling; John O'Brien; Holger Eickhoff; Hans Lehrach; Uwe Radelof
New tools for oligonucleotide fingerprinting.
BioTechniques 2001;31(3):490-5.
2001: Matthew Clark; Steffen Hennig; Ralf Herwig; S W Clifton; M A Marra; Hans Lehrach; S L Johnson
An oligonucleotide fingerprint normalized and expressed sequence tag characterized zebrafish cDNA library.
Genome research 2001;11(9):1594-602.
2001: Stephanie Waelter; Eberhard Scherzinger; Renate Hasenbank; Eckhard Nordhoff; Rudi Lurz; Heike Goehler; C Gauss; Kirupa Sathasivam; Gillian P Bates; Hans Lehrach; Erich E Wanker
The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.
Human molecular genetics 2001;10(17):1807-17.
2001: Eckhard Nordhoff; Volker Egelhofer; Patrick Giavalisco; Holger Eickhoff; Martin Horn; T Przewieslik; Dorothea Theiss; U Schneider; Hans Lehrach; Johan Gobom
Large-gel two-dimensional electrophoresis-matrix assisted laser desorption/ionization-time of flight-mass spectrometry: an analytical challenge for studying complex protein mixtures.
Electrophoresis 2001;22(14):2844-55.
2001: Matthias Steinfath; Wasco Wruck; H Seidel; Hans Lehrach; Uwe Radelof; John O'Brien
Automated image analysis for array hybridization experiments.
Bioinformatics (Oxford, England) 2001;17(7):634-41.
2001: Erhard Hofer; Yuri Sobanov; Christine Brostjan; Hans Lehrach; M Düchler
The centromeric part of the human natural killer (NK) receptor complex: lectin-like receptor genes expressed in NK, dendritic and endothelial cells.
Immunological reviews 2001;181():5-19.
2001: A Sittler; Rudi Lurz; G Lueder; J Priller; Hans Lehrach; Manajit Hayer-Hartl; F Ulrich Hartl; Erich E Wanker
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease.
Human molecular genetics 2001;10(12):1307-15.
2001: Alexander Hüttenhofer; Martin Kiefmann; S Meier-Ewert; J O'Brien; Hans Lehrach; Jean-Pierre Bachellerie; Jürgen Brosius
RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse.
The EMBO journal 2001;20(11):2943-53.
2001: Stephanie Waelter; Annett Boeddrich; Rudi Lurz; Eberhard Scherzinger; G Lueder; Hans Lehrach; Erich E Wanker
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation.
Molecular biology of the cell 2001;12(5):1393-407.
2001: Johan Gobom; M Schuerenberg; M Mueller; Dorothea Theiss; Hans Lehrach; Eckhard Nordhoff
Alpha-cyano-4-hydroxycinnamic acid affinity sample preparation. A protocol for MALDI-MS peptide analysis in proteomics.
Analytical chemistry 2001;73(3):434-8.
2001: Uwe Mueller; Lajos Nyarsik; Martin Horn; H Rauth; T Przewieslik; Wolfram Saenger; Hans Lehrach; Holger Eickhoff
Development of a technology for automation and miniaturization of protein crystallization.
Journal of biotechnology 2001;85(1):7-14.
2001: Konrad Büssow; Zoltán Konthur; Angelika Lueking; Hans Lehrach; Gerald Walter
Protein array technology. Potential use in medical diagnostics.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2001;1(1):37-43.
2001: Reto Crameri; Rimantas Kodzius; Zoltán Konthur; Hans Lehrach; Kurt Blaser; Gerald Walter
Tapping allergen repertoires by advanced cloning technologies.
International archives of allergy and immunology 2001;124(1-3):43-7.
2001: Ralf Sudbrak; Georg Wieczorek; Ulrike A Nuber; W Mann; R Kirchner; Fikret Erdogan; C J Brown; D Wöhrle; P Sterk; Vera Kalscheuer; Wolfgang Berger; Hans Lehrach; Hans-Hilger Ropers
X chromosome-specific cDNA arrays: identification of genes that escape from X-inactivation and other applications.
Human molecular genetics 2001;10(1):77-83.
2001: Heymut Omran; Karsten Häffner; S Burth; C Fernandez; B Fargier; A Villaquiran; Hans Gerd Nothwang; S Schnittger; Hans Lehrach; David D Woo; Matthias Brandis; Ralf Sudbrak; Friedhelm Hildebrandt
Human adolescent nephronophthisis: gene locus synteny with polycystic kidney disease in pcy mice.
Journal of the American Society of Nephrology : JASN 2001;12(1):107-13.
2000: Christine Brostjan; Yuri Sobanov; J Glienke; Silvia Hayer; Hans Lehrach; Fiona Francis; Erhard Hofer
The NKG2 natural killer cell receptor family: comparative analysis of promoter sequences.
Genes and immunity 2000;1(8):504-8.
2000: Sascha Sauer; Doris Lechner; Kurt Berlin; C Plançon; A Heuermann; Hans Lehrach; Ivo Gut
Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay.
Nucleic acids research 2000;28(23):E100.
2000: Angelika Lueking; Caterina Holz; C Gotthold; Hans Lehrach; D Cahill
A system for dual protein expression in Pichia pastoris and Escherichia coli.
Protein expression and purification 2000;20(3):372-8.
2000: Claudia Gösele; L Hong; Thomas Kreitler; M Rossmann; B Hieke; U Gross; M Kramer; Heinz Himmelbauer; M T Bihoreau; AE Kwitek-Black; Simon N Twigger; Peter Tonellato; H J Jacob; Leonard C Schalkwyk; Klaus Lindpaintner; Detlev Ganten; Hans Lehrach; Margit Knoblauch
High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers.
Genomics 2000;69(3):287-94.
2000: Lorenz Neidhardt; S Gasca; Karin Wertz; F Obermayr; S Worpenberg; Hans Lehrach; Bernhard G Herrmann
Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Mechanisms of development 2000;98(1-2):77-94.
2000: Minori Shinya; C Eschbach; M Clark; Hans Lehrach; Makoto Furutani-Seiki
Zebrafish Dkk1, induced by the pre-MBT Wnt signaling, is secreted from the prechordal plate and patterns the anterior neural plate.
Mechanisms of development 2000;98(1-2):3-17.
2000: Stefan Schreiber; Jochen Hampe; Holger Eickhoff; Hans Lehrach
Functional genomics in gastroenterology.
Gut 2000;47(5):601-7.
2000: Eckhard Nordhoff; C Luebbert; G Thiele; Volker Heiser; Hans Lehrach
Rapid determination of short DNA sequences by the use of MALDI-MS.
Nucleic acids research 2000;28(20):E86.
2000: Ralf Herwig; A O Schmitt; Matthias Steinfath; John O'Brien; H Seidel; S Meier-Ewert; Hans Lehrach; Uwe Radelof
Information theoretical probe selection for hybridisation experiments.
Bioinformatics (Oxford, England) 2000;16(10):890-8.
2000: Holger Eickhoff; Johannes Schuchhardt; I Ivanov; Sebastian Meier-Ewert; John O'Brien; A Malik; N Tandon; Witold Eryk Wolski; E Rohlfs; Lajos Nyarsik; R Reinhardt; Wilfried Nietfeld; Hans Lehrach
Tissue gene expression analysis using arrayed normalized cDNA libraries.
Genome research 2000;10(8):1230-40.
2000: M Schuerenberg; C Luebbert; Holger Eickhoff; M Kalkum; Hans Lehrach; Eckhard Nordhoff
Prestructured MALDI-MS sample supports.
Analytical chemistry 2000;72(15):3436-42.
2000: Volker Egelhofer; Konrad Büssow; C Luebbert; Hans Lehrach; Eckhard Nordhoff
Improvements in protein identification by MALDI-TOF-MS peptide mapping.
Analytical chemistry 2000;72(13):2741-50.
2000: E Hartuv; A O Schmitt; J Lange; S Meier-Ewert; Hans Lehrach; Ron Shamir
An algorithm for clustering cDNA fingerprints.
Genomics 2000;66(3):249-56.
2000: Volker Heiser; Eberhard Scherzinger; Annett Boeddrich; Eckhard Nordhoff; Rudi Lurz; Nancy Schugardt; Hans Lehrach; Erich E Wanker
Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6739-44.
2000: Johannes Schuchhardt; Dieter Beule; A Malik; Witold Eryk Wolski; Holger Eickhoff; Hans Lehrach; Hanspeter Herzel
Normalization strategies for cDNA microarrays.
Nucleic acids research 2000;28(10):E47.
2000: Ralf Sudbrak; J Brown; Carol Dobson-Stone; S Carter; J Ramser; J White; E Healy; M Dissanayake; M Larrègue; M Perrussel; Hans Lehrach; Colin S Munro; Tom Strachan; Susan Burge; Alain Hovnanian; Anthony P Monaco
Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.
Human molecular genetics 2000;9(7):1131-40.
2000: Konrad Büssow; Eckhard Nordhoff; C Lübbert; Hans Lehrach; G Walter
A human cDNA library for high-throughput protein expression screening.
Genomics 2000;65(1):1-8.
2000: M Schubert; Linda Z Holland; GD Panopoulou; Hans Lehrach; Nicholas D Holland
Characterization of amphioxus AmphiWnt8: insights into the evolution of patterning of the embryonic dorsoventral axis.
Evolution & development 2000;2(2):85-92.
2000: Sascha Sauer; Doris Lechner; Kurt Berlin; Hans Lehrach; J L Escary; Nick C Fox; Ivo Gut
A novel procedure for efficient genotyping of single nucleotide polymorphisms.
Nucleic acids research 2000;28(5):E13.
2000: Heinz Himmelbauer; Leonard C Schalkwyk; Hans Lehrach
Interspersed repetitive sequence (IRS)-PCR for typing of whole genome radiation hybrid panels.
Nucleic acids research 2000;28(2):e7.
2000: C Bull; Yuri Sobanov; B Röhrdanz; J O'Brien; Hans Lehrach; Erhard Hofer
The centromeric part of the human NK gene complex: linkage of LOX-1 and LY49L with the CD94/NKG2 region.
Genes and immunity 2000;1(4):280-7.
2000: M V Wiles; Franz Vauti; Jürgen Otte; Ernst-Martin Füchtbauer; Patricia Ruiz; Annette C Füchtbauer; Hans-Henning Arnold; Hans Lehrach; T Metz; Harald von Melchner; Wolfgang Wurst
Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.
Nature genetics 2000;24(1):13-4.
1999: Evgeni B. Starikov; Hans Lehrach; Erich E Wanker
Folding of oligoglutamines: a theoretical approach based upon thermodynamics and molecular mechanics.
Journal of biomolecular structure & dynamics 1999;17(3):409-27.
1999: Ralf Herwig; A J Poustka; C Müller; C Bull; Hans Lehrach; John O'Brien
Large-scale clustering of cDNA-fingerprinting data.
Genome research 1999;9(11):1093-105.
1999: Leonard C Schalkwyk; M Jung; A Daser; M Weiher; J Walter; Heinz Himmelbauer; Hans Lehrach
Panel of microsatellite markers for whole-genome scans and radiation hybrid mapping and a mouse family tree.
Genome research 1999;9(9):878-87.
1999: Annemarie Poustka; Ralf Herwig; A Krause; Steffen Hennig; S Meier-Ewert; Hans Lehrach
Toward the gene catalogue of sea urchin development: the construction and analysis of an unfertilized egg cDNA library highly normalized by oligonucleotide fingerprinting.
Genomics 1999;59(2):122-33.
1999: B Hollenbach; Eberhard Scherzinger; K Schweiger; Rudi Lurz; Hans Lehrach; Erich E Wanker
Aggregation of truncated GST-HD exon 1 fusion proteins containing normal range and expanded glutamine repeats.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1386):991-4.
1999: Angelika Lueking; Martin Horn; Holger Eickhoff; Konrad Büssow; Hans Lehrach; Gerald Walter
Protein microarrays for gene expression and antibody screening.
Analytical biochemistry 1999;270(1):103-11.
1999: A Vente; Bernhard Korn; G Zehetner; Annemarie Poustka; Hans Lehrach
Distribution and early development of microarray technology in Europe.
Nature genetics 1999;22(1):22.
1999: Annett Boeddrich; Carola Burgtorf; Fiona Francis; Steffen Hennig; Georgia Panopoulou; C Steffens; Katja Borzym; Hans Lehrach
Sequence analysis of an amphioxus cosmid containing a gene homologous to members of the aldo-keto reductase gene superfamily.
Gene 1999;230(2):207-14.
1999: Eberhard Scherzinger; A Sittler; K Schweiger; Volker Heiser; Rudi Lurz; Renate Hasenbank; Gillian P Bates; Hans Lehrach; Erich E Wanker
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4604-9.
1999: C Nock; C Gauss; Leonard C Schalkwyk; Joachim Klose; Hans Lehrach; Heinz Himmelbauer
Technology development at the interface of proteome research and genomics: mapping nonpolymorphic proteins on the physical map of mouse chromosomes.
Electrophoresis 1999;20(4-5):1027-32.
1999: T Hildmann; X Kong; J O'Brien; L Riesselman; HM Christensen; E Dagand; Hans Lehrach; Marie-Laure Yaspo
A contiguous 3-Mb sequence-ready map in the S3-MX region on 21q22.2 based on high- throughput nonisotopic library screenings.
Genome research 1999;9(4):360-72.
1999: Annett Boeddrich; Carola Burgtorf; Hugues Roest Crollius; Steffen Hennig; Alain Bernot; M Clark; Richard Reinhardt; Hans Lehrach; Fiona Francis
Analysis of the spermine synthase gene region in Fugu rubripes, Tetraodon fluviatilis, and Danio rerio.
Genomics 1999;57(1):164-8.
1999: C Gauss; M Kalkum; M Löwe; Hans Lehrach; Joachim Klose
Analysis of the mouse proteome. (I) Brain proteins: separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation.
Electrophoresis 1999;20(3):575-600.
1999: Peter Seranski; Nina S Heiss; S Dhorne-Pollet; Uwe Radelof; Bernhard Korn; Steffen Hennig; E Backes; S Schmidt; Stefan Wiemann; C E Schwarz; Hans Lehrach; Annemarie Poustka
Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes.
Genomics 1999;56(1):1-11.
1999: K Blechschmidt; M Schweiger; K Wertz; R Poulson; HM Christensen; André Rosenthal; Hans Lehrach; Marie-Laure Yaspo
The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.
Genome research 1999;9(2):158-66.
1999: C Rinderle; HM Christensen; Susann Schweiger; Hans Lehrach; Marie-Laure Yaspo
AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers.
Human molecular genetics 1999;8(2):277-90.
1999: Yuri Sobanov; J Glienke; Christine Brostjan; Hans Lehrach; Fiona Francis; Erhard Hofer
Linkage of the NKG2 and CD94 receptor genes to D12S77 in the human natural killer gene complex.
Immunogenetics 1999;49(2):99-105.
1999: Erich E Wanker; Eberhard Scherzinger; Volker Heiser; A Sittler; H Eickhoff; Hans Lehrach
Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates.
Methods in enzymology 1999;309():375-86.
1999: Matthew Clark; GD Panopoulou; D J Cahill; K Büssow; Hans Lehrach
Construction and analysis of arrayed cDNA libraries.
Methods in enzymology 1999;303():205-33.
1999: U Leser; Hugues Roest Crollius; Hans Lehrach; R Sudbrak
IXDB, an X chromosome integrated database (update).
Nucleic acids research 1999;27(1):123-7.
1998: Ulrich Zechner; S Scheel; Myriam Hemberger; M Hopp; Thomas Haaf; Reinald Fundele; Erich E Wanker; Hans Lehrach; N Wedemeyer; Heinz Himmelbauer
Characterization of the mouse Src homology 3 domain gene Sh3d2c on Chr 7 demonstrates coexpression with huntingtin in the brain and identifies the processed pseudogene Sh3d2c-ps1 on Chr 2.
Genomics 1998;54(3):505-10.
1998: Uwe Radelof; Steffen Hennig; Peter Seranski; Matthias Steinfath; J Ramser; Richard Reinhardt; Annemarie Poustka; Fiona Francis; Hans Lehrach
Preselection of shotgun clones by oligonucleotide fingerprinting: an efficient and high throughput strategy to reduce redundancy in large-scale sequencing projects.
Nucleic acids research 1998;26(23):5358-64.
1998: Konrad Büssow; D Cahill; W Nietfeld; D Bancroft; Eberhard Scherzinger; Hans Lehrach; G Walter
A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library.
Nucleic acids research 1998;26(21):5007-8.
1998: A Sittler; Stephanie Wälter; N Wedemeyer; Renate Hasenbank; Eberhard Scherzinger; H Eickhoff; Gillian P Bates; Hans Lehrach; Erich E Wanker
SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
Molecular cell 1998;2(4):427-36.
1998: Leonard C Schalkwyk; M Weiher; M Kirby; Brian Cusack; Heinz Himmelbauer; Hans Lehrach
Refined radiation hybrid map of mouse chromosome 17.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(10):807-11.
1998: Carola Burgtorf; K Welzel; R Hasenbank; G Zehetner; S Weis; Hans Lehrach
Gridded genomic libraries of different chordate species: a reference library system for basic and comparative genetic studies of chordate genomes.
Genomics 1998;52(2):230-2.
1998: GD Panopoulou; Matthew Clark; Linda Z Holland; Hans Lehrach; Nicholas D Holland
AmphiBMP2/4, an amphioxus bone morphogenetic protein closely related to Drosophila decapentaplegic and vertebrate BMP2 and BMP4: insights into evolution of dorsoventral axis specification.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;213(1):130-9.
1998: J Glienke; Yuri Sobanov; Christine Brostjan; C Steffens; C Nguyen; Hans Lehrach; Erhard Hofer; Fiona Francis
The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.
Immunogenetics 1998;48(3):163-73.
1998: Heinz Himmelbauer; I Dunkel; G W Otto; Carola Burgtorf; Leonard C Schalkwyk; Hans Lehrach
Complex probes for high-throughput parallel genetic mapping of genomic mouse BAC clones.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(8):611-6.
1998: D Tait; M Riccio; A Sittler; Eberhard Scherzinger; Spartaco Santi; Andrea Ognibene; Nadir M Maraldi; Hans Lehrach; Erich E Wanker
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.
Human molecular genetics 1998;7(6):991-7.
1998: Y Georgalis; Evgeni B. Starikov; B Hollenbach; Rudi Lurz; Eberhard Scherzinger; Wolfram Saenger; Hans Lehrach; Erich E Wanker
Huntingtin aggregation monitored by dynamic light scattering.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6118-21.
1998: S Meier-Ewert; J Lange; H Gerst; Ralf Herwig; A Schmitt; J Freund; Thorsten Elge; R Mott; B Herrmann; Hans Lehrach
Comparative gene expression profiling by oligonucleotide fingerprinting.
Nucleic acids research 1998;26(9):2216-23.
1998: F Bertaux; A H Sharp; Christopher A Ross; Hans Lehrach; Gillian P Bates; Erich E Wanker
HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice.
FEBS letters 1998;426(2):229-32.
1998: Martin Beye; A Poch; C Burgtorf; R F Moritz; Hans Lehrach
A gridded genomic library of the honeybee (Apis mellifera): a reference library system for basic and comparative genetic studies of a hymenopteran genome.
Genomics 1998;49(2):317-20.
1998: A Rodríguez; M Carretero; J Glienke; Teresa Bellón; A Ramírez; Hans Lehrach; Fiona Francis; Miguel López-Botet
Structure of the human CD94 C-type lectin gene.
Immunogenetics 1998;47(4):305-9.
1998: Birgit Lorenz; Fiona Francis; Klaus Gempel; A Böddrich; M Josten; Wolfgang Schmahl; J Schmidt; Hans Lehrach; Thomas Meitinger; Tim M Strom
Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
Human molecular genetics 1998;7(3):541-7.
1998: Nadia Dahmane; G A Ghezala; P Gosset; Z Chamoun; M C Dufresne-Zacharia; Carmela Lopes; N Rabatel; S Gassanova-Maugenre; Zoubida Chettouh; V Abramowski; E Fayet; Marie-Laure Yaspo; Bernd Korn; J L Blouin; Hans Lehrach; A Poutska; Stylianos E Antonarakis; Pierre-Marie Sinet; Nicole Créau; Jean-Maurice Delabar
Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.
Genomics 1998;48(1):12-23.
1998: U Leser; Hans Lehrach; Hugues Roest Crollius
Issues in developing integrated genomic databases and application to the human X chromosome.
Bioinformatics (Oxford, England) 1998;14(7):583-90.
1998: A Grigoriev; A Levin; Hans Lehrach
A distributed environment for physical map construction.
Bioinformatics (Oxford, England) 1998;14(3):252-8.
1998: Heinz Himmelbauer; N Wedemeyer; Thomas Haaf; Erich E Wanker; Leonard C Schalkwyk; Hans Lehrach
IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse chromosome 5.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(1):26-31.
1998: U Leser; R Wagner; A Grigoriev; Hans Lehrach; Hugues Roest Crollius
IXDB, an X chromosome integrated database.
Nucleic acids research 1998;26(1):108-11.
1997: N Wedemeyer; R Peoples; Heinz Himmelbauer; Hans Lehrach; U Francke; Erich E Wanker
Localization of the human HIP1 gene close to the elastin (ELN) locus on 7q11.23.
Genomics 1997;46(2):313-5.
1997: Kirupa Sathasivam; S Baxendale; L Mangiarini; F Bertaux; C Hetherington; I Kanazawa; Hans Lehrach; Gillian P Bates
Aberrant processing of the Fugu HD (FrHD) mRNA in mouse cells and in transgenic mice.
Human molecular genetics 1997;6(12):2141-9.
1997: D R Bancroft; J K O'Brien; A Guerasimova; Hans Lehrach
Simplified handling of high-density genetic filters using rigid plastic laminates.
Nucleic acids research 1997;25(20):4160-1.
1997: P Gosset; G A Ghezala; Bernd Korn; Marie-Laure Yaspo; A Poutska; Hans Lehrach; Pierre-Marie Sinet; Nicole Créau
A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1).
Genomics 1997;44(2):237-41.
1997: Nicholas D Holland; S C Zhang; M Clark; GD Panopoulou; Hans Lehrach; Linda Z Holland
Sequence and developmental expression of AmphiTob, an amphioxus homolog of vertebrate Tob in the PC3/BTG1/Tob family of tumor suppressor genes.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;210(1):11-8.
1997: Eberhard Scherzinger; Rudi Lurz; Mark Turmaine; L Mangiarini; B Hollenbach; Renate Hasenbank; Gillian P Bates; SW Davies; Hans Lehrach; Erich E Wanker
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
Cell 1997;90(3):549-58.
1997: Fiona Francis; Tim M Strom; Steffen Hennig; A Böddrich; Birgit Lorenz; Oliver Brandau; Klaus Mohnike; M Cagnoli; C Steffens; S Klages; Katja Borzym; T Pohl; Claudine Oudet; Michael J Econs; Peter S N Rowe; Richard Reinhardt; Thomas Meitinger; Hans Lehrach
Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets.
Genome research 1997;7(6):573-85.
1997: Tatjana Crnogorac-Jurcevic; J R Brown; Hans Lehrach; L C Schalkwyk
Tetraodon fluviatilis, a new puffer fish model for genome studies.
Genomics 1997;41(2):177-84.
1997: Peter S N Rowe; Claudine Oudet; Fiona Francis; Christiane Sinding; Solange Pannetier; Michael J Econs; Tim M Strom; Thomas Meitinger; M Garabedian; A David; M A Macher; E Questiaux; Ewa Popowska; Ewa Pronicka; A P Read; A Mokrzycki; Francis Glorieux; Marc K Drezner; André Hanauer; Hans Lehrach; J N Goulding; Jeffrey L H O'Riordan
Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP).
Human molecular genetics 1997;6(4):539-49.
1997: Erich E Wanker; C Rovira; Eberhard Scherzinger; Renate Hasenbank; Stephanie Wälter; D Tait; J Colicelli; Hans Lehrach
HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system.
Human molecular genetics 1997;6(3):487-95.
1997: Tim M Strom; Fiona Francis; Birgit Lorenz; A Böddrich; Michael J Econs; Hans Lehrach; Thomas Meitinger
Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia.
Human molecular genetics 1997;6(2):165-71.
1996: L Mangiarini; Kirupa Sathasivam; MJ Seller; B Cozens; A Harper; C Hetherington; M Lawton; Y Trottier; Hans Lehrach; SW Davies; Gillian P Bates
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
Cell 1996;87(3):493-506.
1996: Hugues Roest Crollius; Mark T Ross; A Grigoriev; C J Knights; E Holloway; J Misfud; K Li; M Playford; S G Gregory; Sean Humphray; A J Coffey; Chee Gee See; S Marsh; Radost Vatcheva; J Kumlien; T Labella; V Lam; K H Rak; K Todd; R Mott; D Graeser; G Rappold; G Zehetner; A Poustka; D R Bentley; Anthony P Monaco; Hans Lehrach
An integrated YAC map of the human X chromosome.
Genome research 1996;6(10):943-55.
1996: J Kumlien; A Grigoriev; Hugues Roest Crollius; M Ross; P N Goodfellow; Hans Lehrach
A radiation hybrid map spanning the entire human X chromosome integrating YACs, genes, and STS markers.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(10):758-66.
1996: A M Tomlinson; R D Cox; Hans Lehrach; M A Dalrymple
Restriction map of two yeast artificial chromosomes spanning the murine casein locus.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(7):542-4.
1996: Kazutoyo Osoegawa; R Susukida; S Okano; Y Kato; Hans Lehrach; Dean Nizetic; E Soeda
Potential CpG-rich islands clustering around single-minded gene in Down syndrome chromosomal region.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(6):461-3.
1996: K W Hunter; L Riba; L Schalkwyk; M Clark; S Resenchuk; A Beeghly; J Su; F Tinkov; P Lee; E Ramu; Hans Lehrach; D Housman
Toward the construction of integrated physical and genetic maps of the mouse genome using interspersed repetitive sequence PCR (IRS-PCR) genomics.
Genome research 1996;6(4):290-9.
1996: Kazutoyo Osoegawa; R Susukida; S Okano; J Kudoh; S Minoshima; N Shimizu; Pieter J de Jong; Jürgen Groet; JH Ives; Hans Lehrach; Dean Nizetic; E Soeda
An integrated map with cosmid/PAC contigs of a 4-Mb Down syndrome critical region.
Genomics 1996;32(3):375-87.
1996: Peter S N Rowe; J N Goulding; Fiona Francis; Claudine Oudet; Michael J Econs; André Hanauer; Hans Lehrach; A P Read; R C Mountford; T Summerfield; J Weissenbach; W Fraser; Marc K Drezner; Kay E Davies; Jeffrey L H O'Riordan
The gene for X-linked hypophosphataemic rickets maps to a 200-300kb region in Xp22.1, and is located on a single YAC containing a putative vitamin D response element (VDRE).
Human genetics 1996;97(3):345-52.
1996: Sona Gregorová; M Mnuková-Fajdelová; Zdenek Trachtulec; J Capková; M Loudová; M Hoglund; RM Hamvas; Hans Lehrach; Vladimir Vincek; Jan Klein; Jiri Forejt
Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(2):107-13.
1996: Zoia Larin; Anthony P Monaco; Hans Lehrach
Generation of large insert YAC libraries.
Methods in molecular biology (Clifton, N.J.) 1996;54():1-11.
1995: W R Newell; R Mott; S Beck; Hans Lehrach
Construction of genetic maps using distance geometry.
Genomics 1995;30(1):59-70.
1995: P Scholler; A E Karger; S Meier-Ewert; Hans Lehrach; Hajo Delius; Jörg D Hoheisel
Fine-mapping of shotgun template-libraries; an efficient strategy for the systematic sequencing of genomic DNA.
Nucleic acids research 1995;23(19):3842-9.
1995: H Hummerich; Hans Lehrach
Trinucleotide repeat expansion and human disease.
Electrophoresis 1995;16(9):1698-704.
1995: RM Hamvas; Hans Lehrach
Repetitive sequence fingerprinting in the long range mapping of mammalian genomes.
Electrophoresis 1995;16(9):1602-6.
1995: Marie-Laure Yaspo; L Gellen; R Mott; Bernd Korn; Dean Nizetic; A M Poustka; Hans Lehrach
Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries.
Human molecular genetics 1995;4(8):1291-304.
1995: H F Sutherland; E Pick; Fiona Francis; Hans Lehrach; A M Frischauf
Mapping around the Fused locus on mouse chromosome 17.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(7):449-53.
1995: Elsy P Jones; H Xiao; Roger A Schultz; L Flaherty; Zdenek Trachtulec; Vladimir Vincek; Z Larin; Hans Lehrach; Kirsten Fischer Lindahl
MHC class I gene organization in > 1.5-Mb YAC contigs from the H2-M region.
Genomics 1995;27(1):40-51.
1995: L C Schalkwyk; Fiona Francis; Hans Lehrach
Techniques in mammalian genome mapping.
Current opinion in biotechnology 1995;6(1):37-43.
1994: M Höglund; Hans Lehrach
The construction of a beta-lactamase-encoding ApR gene cassette flanked by recognition sites for NotI, SacII, MluI, SplI, BssHII and NarI.
Gene 1994;150(1):193-4.
1994: Dean Nizetic; S Monard; B Young; F Cotter; G Zehetner; Hans Lehrach
Construction of cosmid libraries from flow-sorted human chromosomes 1, 6, 7, 11, 13, and 18 for reference library resources.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(12):801-2.
1994: Zdenek Trachtulec; Vladimir Vincek; RM Hamvas; Jiri Forejt; Hans Lehrach; Jan Klein
Physical map of mouse chromosome 17 in the region relevant for positional cloning of the Hybrid sterility 1 gene.
Genomics 1994;23(1):132-7.
1994: E Maier; H Roest Crollius; Hans Lehrach
Hybridisation techniques on gridded high density DNA and in situ colony filters based on fluorescence detection.
Nucleic acids research 1994;22(16):3423-4.
1994: A Grigoriev; R Mott; Hans Lehrach
An algorithm to detect chimeric clones and random noise in genomic mapping.
Genomics 1994;22(2):482-6.
1994: E Maier; S Meier-Ewert; A R Ahmadi; J Curtis; Hans Lehrach
Application of robotic technology to automated sequence fingerprint analysis by oligonucleotide hybridisation.
Journal of biotechnology 1994;35(2-3):191-203.
1994: Jörg D Hoheisel; Mark T Ross; G Zehetner; Hans Lehrach
Relational genome analysis using reference libraries and hybridisation fingerprinting.
Journal of biotechnology 1994;35(2-3):121-34.
1994: J Kumlien; T Labella; G Zehetner; Radost Vatcheva; Dean Nizetic; Hans Lehrach
Efficient identification and regional positioning of YAC and cosmid clones to human chromosome 21 by radiation fusion hybrids.
Mammalian genome : official journal of the International Mammalian Genome Society 1994;5(6):365-71.
1994: Anthony P Monaco; Zoia Larin; Hans Lehrach
Construction of yeast artificial chromosome libraries by pulsed-field gel electrophoresis.
Molecular biotechnology 1994;1(3):241-9.
1994: R D Cox; Alexandra Shedlovsky; RM Hamvas; M Goldsworthy; J Whittington; C S Connelly; William F Dove; Hans Lehrach
A 1.2-Mb YAC contig spans the quaking region.
Genomics 1994;21(1):77-84.
1994: Fiona Francis; Peter S N Rowe; Michael J Econs; Chee Gee See; F Benham; Jeffrey L H O'Riordan; Marc K Drezner; RM Hamvas; Hans Lehrach
A YAC contig spanning the hypophosphatemic rickets disease gene (HYP) candidate region.
Genomics 1994;21(1):229-37.
1994: RM Hamvas; Fiona Francis; R D Cox; Dean Nizetic; M E Goldsworthy; S D Brown; Hans Lehrach
Rapid restriction analysis of YAC clones.
Nucleic acids research 1994;22(7):1318-9.
1994: Michael J Econs; Fiona Francis; Peter S N Rowe; Marcy C Speer; Jeffrey L H O'Riordan; Hans Lehrach; P A Becker
Dinucleotide repeat polymorphism at the DXS1683 locus.
Human molecular genetics 1994;3(4):680.
1994: Gillian P Bates; Hans Lehrach
Trinucleotide repeat expansions and human genetic disease.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(4):277-84.
1994: F Gibson; Hans Lehrach; AJ Buckler; S D Brown; M A North
Isolation of conserved sequences from yeast artificial chromosomes by exon amplification.
BioTechniques 1994;16(3):453-8.
1994: Peter S N Rowe; J Goulding; A Read; Hans Lehrach; Fiona Francis; André Hanauer; Claudine Oudet; Valérie Biancalana; S W Kooh; Kay E Davies
Refining the genetic map for the region flanking the X-linked hypophosphataemic rickets locus (Xp22.1-22.2).
Human genetics 1994;93(3):291-4.
1994: Fiona Francis; F Benham; Chee Gee See; M Fox; Y Ishikawa-Brush; Anthony P Monaco; B Weiss; G Rappold; RM Hamvas; Hans Lehrach
Identification of YAC and cosmid clones encompassing the ZFX-POLA region using irradiation hybrid cell lines.
Genomics 1994;20(1):75-83.
1994: G Zehetner; Hans Lehrach
The Reference Library System--sharing biological material and experimental data.
Nature 1994;367(6462):489-91.
1994: C M Ambrose; Mabel P Duyao; G Barnes; Gillian P Bates; C S Lin; J Srinidhi; S Baxendale; H Hummerich; Hans Lehrach; M Altherr
Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat.
Somatic cell and molecular genetics 1994;20(1):27-38.
1994: David Vetrie; E Kendall; A Coffey; S Hassock; J Collins; C Todd; Hans Lehrach; Martin Bobrow; David R Bentley; A Harris
A 6.5-Mb yeast artificial chromosome contig incorporating 33 DNA markers on the human X chromosome at Xq22.
Genomics 1994;19(1):42-7.
1994: H Hummerich; S Baxendale; R Mott; S F Kirby; Marcy E MacDonald; James Gusella; Hans Lehrach; Gillian P Bates
Distribution of trinucleotide repeat sequences across a 2 Mbp region containing the Huntington's disease gene.
Human molecular genetics 1994;3(1):73-8.
1994: Fiona Francis; G Zehetner; M Höglund; Hans Lehrach
Construction and preliminary analysis of the ICRF human P1 library.
Genetic analysis, techniques and applications 1994;11(5-6):148-57.
1993: R D Cox; J Whittington; Alexandra Shedlovsky; C S Connelly; William F Dove; M Goldsworthy; Zoia Larin; Hans Lehrach
Detailed physical and genetic mapping in the region of plasminogen, D17Rp17e, and quaking.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(12):687-94.
1993: Andreas Schedl; Z Larin; Lluis Montoliu; E Thies; G Kelsey; Hans Lehrach; Günther Schütz
A method for the generation of YAC transgenic mice by pronuclear microinjection.
Nucleic acids research 1993;21(20):4783-7.
1993: Niels Tommerup; L Aagaard; C L Lund; E Boel; S Baxendale; Gillian P Bates; Hans Lehrach; Henrik Vissing
A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome.
Human molecular genetics 1993;2(10):1571-5.
1993: M A North; P Sanseau; AJ Buckler; D Church; A Jackson; K Patel; J Trowsdale; Hans Lehrach
Efficiency and specificity of gene isolation by exon amplification.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(9):466-74.
1993: Peter S N Rowe; J Goulding; A Read; R Mountford; André Hanauer; Claudine Oudet; M P Whyte; S Meier-Ewert; Hans Lehrach; Kay E Davies
New markers for linkage analysis of X-linked hypophosphataemic rickets.
Human genetics 1993;91(6):571-5.
1993: Jörg D Hoheisel; Hans Lehrach
Use of reference libraries and hybridisation fingerprinting for relational genome analysis.
FEBS letters 1993;325(1-2):118-22.
1993: Marie-Laure Yaspo; M A North; Hans Lehrach
Exon-enriched probe derived from a human chromosome 21 YAC by exon-amplification.
Nucleic acids research 1993;21(9):2271-2.
1993: R Mott; A Grigoriev; E Maier; Jörg D Hoheisel; Hans Lehrach
Algorithms and software tools for ordering clone libraries: application to the mapping of the genome of Schizosaccharomyces pombe.
Nucleic acids research 1993;21(8):1965-74.
1993: Jörg D Hoheisel; E Maier; R Mott; L McCarthy; A V Grigoriev; L C Schalkwyk; Dean Nizetic; Fiona Francis; Hans Lehrach
High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe.
Cell 1993;73(1):109-20.
1993: Gillian P Bates; Hans Lehrach
The Huntington disease gene--still a needle in a haystack?
Human molecular genetics 1993;2(4):343-7.
1993: S Meier-Ewert; E Maier; A Ahmadi; J Curtis; Hans Lehrach
An automated approach to generating expressed sequence catalogues.
Nature 1993;361(6410):375-6.
1993: R D Cox; S Meier-Ewert; M Ross; Zoia Larin; Anthony P Monaco; Hans Lehrach
Genome mapping and cloning of mutations using yeast artificial chromosomes.
Methods in enzymology 1993;225():637-53.
1993: Zoia Larin; Anthony P Monaco; S Meier-Ewert; Hans Lehrach
Construction and characterization of yeast artificial chromosome libraries from the mouse genome.
Methods in enzymology 1993;225():623-37.
1993: Shinji Hadano; Y Ishida; Gillian P Bates; T Nagayama; I Kanazawa; Hans Lehrach; J Ikeda
Generation of high-density DNA markers from yeast artificial chromosome DNA by single unique primer-polymerase chain reaction.
Genetic analysis, techniques and applications 1993;10(5):105-8.
1993: Jörg D Hoheisel; E Maier; S Meier-Ewert; Hans Lehrach
Relational genome analysis based on hybridisation techniques.
Annales de biologie clinique 1993;51(9):827-9.
1993: Lluis Montoliu; Andreas Schedl; G Kelsey; Peter Lichter; Z Larin; Hans Lehrach; Günther Schütz
Generation of transgenic mice with yeast artificial chromosomes.
Cold Spring Harbor symposia on quantitative biology 1993;58():55-62.
1992: A Baldini; M Ross; Dean Nizetic; Radost Vatcheva; E A Lindsay; Hans Lehrach; Marcello Siniscalco
Chromosomal assignment of human YAC clones by fluorescence in situ hybridization: use of single-yeast-colony PCR and multiple labeling.
Genomics 1992;14(1):181-4.
1992: Bernhard Korn; Z Sedlacek; A Manca; Petra Kioschis; D Konecki; Hans Lehrach; Annemarie Poustka
A strategy for the selection of transcribed sequences in the Xq28 region.
Human molecular genetics 1992;1(4):235-42.
1992: E Maier; Jörg D Hoheisel; L McCarthy; R Mott; A V Grigoriev; Anthony P Monaco; Zoia Larin; Hans Lehrach
Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes.
Nature genetics 1992;1(4):273-7.
1992: Anthony P Monaco; A P Walker; I Millwood; Zoia Larin; Hans Lehrach
A yeast artificial chromosome contig containing the complete Duchenne muscular dystrophy gene.
Genomics 1992;12(3):465-73.
1992: Anthony P Monaco; Z Lark; Hans Lehrach
Construction of yeast artificial chromosome libraries by pulsed-field gel electrophoresis.
Methods in molecular biology (Clifton, N.J.) 1992;12():225-34.
1992: Thomas M Gress; Jörg D Hoheisel; G G Lennon; G Zehetner; Hans Lehrach
Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(11):609-19.
1991: S Baxendale; Gillian P Bates; Marcy E MacDonald; James Gusella; Hans Lehrach
The direct screening of cosmid libraries with YAC clones.
Nucleic acids research 1991;19(23):6651.
1991: Anthony P Monaco; U Müller; Zoia Larin; S Meier-Ewert; Hans Lehrach
Isolation of the human sex determining region from a Y-enriched yeast artificial chromosome library.
Genomics 1991;11(4):1049-53.
1991: R Drmanac; Dean Nizetic; G G Lennon; A Beitverda; Hans Lehrach
W (A or T) sequences as probes and primers suitable for genomic mapping and fingerprinting.
Nucleic acids research 1991;19(21):5839-42.
1991: Annemarie Poustka; A Dietrich; G Langenstein; Daniela Toniolo; Stephen Warren; Hans Lehrach
Physical map of human Xq27-qter: localizing the region of the fragile X mutation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8302-6.
1991: Marcy E MacDonald; C Lin; L Srinidhi; Gillian P Bates; M Altherr; W L Whaley; Hans Lehrach; J Wasmuth; James Gusella
Complex patterns of linkage disequilibrium in the Huntington disease region.
American journal of human genetics 1991;49(4):723-34.
1991: C S Lin; M Altherr; Gillian P Bates; W L Whaley; A P Read; R Harris; Hans Lehrach; J J Wasmuth; James Gusella; Marcy E MacDonald
New DNA markers in the Huntington's disease gene candidate region.
Somatic cell and molecular genetics 1991;17(5):481-8.
1991: Jörg D Hoheisel; G G Lennon; G Zehetner; Hans Lehrach
Use of high coverage reference libraries of Drosophila melanogaster for relational data analysis. A step towards mapping and sequencing of the genome.
Journal of molecular biology 1991;220(4):903-14.
1991: G G Lennon; R Drmanac; Hans Lehrach
Easy removal of oil from microtiter dishes following PCR.
BioTechniques 1991;11(2):185.
1991: Marcy E MacDonald; H S Scott; W L Whaley; T Pohl; J J Wasmuth; Hans Lehrach; C P Morris; A M Frischauf; J J Hopwood; James Gusella
Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene.
Somatic cell and molecular genetics 1991;17(4):421-5.
1991: Gillian P Bates; Marcy E MacDonald; S Baxendale; S Youngman; C Lin; W L Whaley; J J Wasmuth; James Gusella; Hans Lehrach
Defined physical limits of the Huntington disease gene candidate region.
American journal of human genetics 1991;49(1):7-16.
1991: Anthony P Monaco; V M Lam; G Zehetner; G G Lennon; C Douglas; Dean Nizetic; P N Goodfellow; Hans Lehrach
Mapping irradiation hybrids to cosmid and yeast artificial chromosome libraries by direct hybridization of Alu-PCR products.
Nucleic acids research 1991;19(12):3315-8.
1991: R D Cox; N G Copeland; N A Jenkins; Hans Lehrach
Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross.
Genomics 1991;10(2):375-84.
1991: Zoia Larin; Anthony P Monaco; Hans Lehrach
Yeast artificial chromosome libraries containing large inserts from mouse and human DNA.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4123-7.
1991: D Nizetić; G Zehetner; Anthony P Monaco; L Gellen; B D Young; Hans Lehrach
Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3233-7.
1991: R D Cox; Hans Lehrach
Genome mapping: PCR based meiotic and somatic cell hybrid analysis.
BioEssays : news and reviews in molecular, cellular and developmental biology 1991;13(4):193-8.
1991: Dean Nizetic; R Drmanac; Hans Lehrach
An improved bacterial colony lysis procedure enables direct DNA hybridisation using short (10, 11 bases) oligonucleotides to cosmids.
Nucleic acids research 1991;19(1):182.
1990: Jörg D Hoheisel; Hans Lehrach
Quantitative measurements on the duplex stability of 2,6-diaminopurine and 5-chloro-uracil nucleotides using enzymatically synthesized oligomers.
FEBS letters 1990;274(1-2):103-6.
1990: Jörg D Hoheisel; A G Craig; Hans Lehrach
Effect of 5-bromo- and 5-methyldeoxycytosine on duplex stability and discrimination of the NotI octadeoxynucleotide. Quantitative measurements using thin-layer chromatography.
The Journal of biological chemistry 1990;265(27):16656-60.
1990: L Stubbs; A Poustka; A Baron; Hans Lehrach; P Lonai; D Duboule
The murine genes Hox-5.1 and Hox-4.1 belong to the same HOX complex on chromosome 2.
Genomics 1990;7(3):422-7.
1990: L Stubbs; J Kraus; Hans Lehrach
The alpha-A-crystallin and cystathionine beta-synthase genes are physically very closely linked in proximal mouse chromosome 17.
Genomics 1990;7(2):284-8.
1990: A G Craig; Dean Nizetic; Jörg D Hoheisel; G Zehetner; Hans Lehrach
Ordering of cosmid clones covering the herpes simplex virus type I (HSV-I) genome: a test case for fingerprinting by hybridisation.
Nucleic acids research 1990;18(9):2653-60.
1990: L Stubbs; C Huxley; B Hogan; T Evans; M Fried; D Duboule; Hans Lehrach
The HOX-5 and surfeit gene clusters are linked in the proximal portion of mouse chromosome 2.
Genomics 1990;6(4):645-50.
1989: Jörg D Hoheisel; Dean Nizetic; Hans Lehrach
Control of partial digestion combining the enzymes dam methylase and MboI.
Nucleic acids research 1989;17(23):9571-82.
1989: A G Craig; Dean Nizetic; Hans Lehrach
Labelling oligonucleotides to high specific activity (I).
Nucleic acids research 1989;17(12):4605-10.
1988: Margit Burmeister; Hans Lehrach
Jekyll, a family of phage-plasmid shuttle vectors.
Gene 1988;73(1):245-50.
1988: G A Rappold; Hans Lehrach
A long range restriction map of the pseudoautosomal region by partial digest PFGE analysis from the telomere.
Nucleic acids research 1988;16(12):5361-77.
1988: Margit Burmeister; Anthony P Monaco; E F Gillard; G J van Ommen; Nabeel A Affara; Malcolm A Ferguson-Smith; Louis Kunkel; Hans Lehrach
A 10-megabase physical map of human Xp21, including the Duchenne muscular dystrophy gene.
Genomics 1988;2(3):189-202.
1988: T C Gilliam; James Gusella; Hans Lehrach
Molecular genetic strategies to investigate Huntington's disease.
Advances in neurology 1988;48():17-29.
1987: F Michiels; A G Craig; G Zehetner; G P Smith; Hans Lehrach
Molecular approaches to genome analysis: a strategy for the construction of ordered overlapping clone libraries.
Computer applications in the biosciences : CABIOS 1987;3(3):203-10.
1987: G A Rappold; L Stubbs; Siegfried Labeit; R B Crkvenjakov; Hans Lehrach
Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island.
The EMBO journal 1987;6(7):1975-80.
1987: M Búcan; B G Herrmann; A M Frischauf; V L Bautch; V Bode; L M Silver; G R Martin; Hans Lehrach
Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex.
Genes & development 1987;1(4):376-85.
1987: A Poustka; T M Pohl; D P Barlow; A M Frischauf; Hans Lehrach
Construction and use of human chromosome jumping libraries from NotI-digested DNA.
Nature 1987;325(6102):353-5.
1987: E Ehrich; A Craig; A Poustka; A M Frischauf; Hans Lehrach
A family of cosmid vectors with the multi-copy R6K replication origin.
Gene 1987;57(2-3):229-37.
1986: A Poustka; T Pohl; D P Barlow; G Zehetner; A Craig; F Michiels; E Ehrich; A M Frischauf; Hans Lehrach
Molecular approaches to mammalian genetics.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 1():131-9.
1985: Hans-Richard Rackwitz; G Zehetner; H Murialdo; H Delius; J H Chai; A Poustka; A Frischauf; Hans Lehrach
Analysis of cosmids using linearization by phage lambda terminase.
Gene 1985;40(2-3):259-66.
1984: Hans-Richard Rackwitz; G Zehetner; A M Frischauf; Hans Lehrach
Rapid restriction mapping of DNA cloned in lambda phage vectors.
Gene 1984;30(1-3):195-200.
1984: A Poustka; Hans-Richard Rackwitz; A M Frischauf; B Hohn; Hans Lehrach
Selective isolation of cosmid clones by homologous recombination in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(13):4129-33.
1982: Herbert Jäckle; J C Almeida; R Galler; H Kluding; Hans Lehrach; J E Edström
Constant and variable parts in the Balbiani ring 2 repeat unit and the translation termination region.
The EMBO journal 1982;1(7):883-8.