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Terho Lehtimäki

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Physiology

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Finland

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Chemicals & Drugs

Genes & Molecular Sequences

Anatomy

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Publications

TOP 3
Pertovaara Marja; Kähönen Mika; Juonala Markus; Laitinen Tomi; Taittonen Leena; Lehtimäki Terho; Viikari Jorma S A; Raitakari Olli T; Hurme Mikko
Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in Young Finns Study.
Anttila Sami; Viikki Merja; Huuhka Kaija; Huuhka Martti; Huhtala Heini; Rontu Riikka; Lehtimäki Terho; Leinonen Esa
TPH2 polymorphisms may modify clinical picture in treatment-resistant depression.
Jylhävä J; Haarala A; Eklund C; Pertovaara M; Kähönen M; Hutri-Kähönen N; Levula M; Lehtimäki T; Huupponen R; Jula A; Juonala M; Viikari J; Raitakari O; Hurme M
Serum amyloid A is independently associated with metabolic risk factors but not with early atherosclerosis: the Cardiovascular Risk in Young Finns Study.

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All Publications

2009: Pertovaara Marja; Kähönen Mika; Juonala Markus; Laitinen Tomi; Taittonen Leena; Lehtimäki Terho; Viikari Jorma S A; Raitakari Olli T; Hurme Mikko
Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in Young Finns Study.
Rheumatology (Oxford, England) 2009;48(12):1553-6.
2009: Anttila Sami; Viikki Merja; Huuhka Kaija; Huuhka Martti; Huhtala Heini; Rontu Riikka; Lehtimäki Terho; Leinonen Esa
TPH2 polymorphisms may modify clinical picture in treatment-resistant depression.
Neuroscience letters 2009;464(1):43-6.
2009: Jylhävä J; Haarala A; Eklund C; Pertovaara M; Kähönen M; Hutri-Kähönen N; Levula M; Lehtimäki T; Huupponen R; Jula A; Juonala M; Viikari J; Raitakari O; Hurme M
Serum amyloid A is independently associated with metabolic risk factors but not with early atherosclerosis: the Cardiovascular Risk in Young Finns Study.
Journal of internal medicine 2009;266(3):286-95.
2009: Soininen Pasi; Kangas Antti J; Würtz Peter; Tukiainen Taru; Tynkkynen Tuulia; Laatikainen Reino; Järvelin Marjo-Riitta; Kähönen Mika; Lehtimäki Terho; Viikari Jorma; Raitakari Olli T; Savolainen Markku J; Ala-Korpela Mika
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism.
The Analyst 2009;134(9):1781-5.
2009: Illi Ari; Setälä-Soikkeli Eija; Viikki Merja; Poutanen Outi; Huhtala Heini; Mononen Nina; Lehtimäki Terho; Leinonen Esa; Kampman Olli
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.
Neuroreport 2009;20(12):1125-8.
2009: Leskinen Yrjö; Paana Tuomas; Saha Heikki; Groundstroem Kaj; Lehtimäki Terho; Kilpinen Sanna; Huhtala Heini; Airaksinen Juhani
Valvular calcification and its relationship to atherosclerosis in chronic kidney disease.
The Journal of heart valve disease 2009;18(4):429-38.
2009: Koskinen Juha; Kähönen Mika; Viikari Jorma S A; Taittonen Leena; Laitinen Tomi; Rönnemaa Tapani; Lehtimäki Terho; Hutri-Kähönen Nina; Pietikäinen Matti; Jokinen Eero; Helenius Hans; Mattsson Noora; Raitakari Olli T; Juonala Markus
Conventional cardiovascular risk factors and metabolic syndrome in predicting carotid intima-media thickness progression in young adults: the cardiovascular risk in young Finns study.
Circulation 2009;120(3):229-36.
2009: Fan Y-M; Raitakari O T; Kähönen M; Hutri-Kähönen N; Juonala M; Marniemi J; Viikari J; Lehtimäki T
Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.
Clinical genetics 2009;76(1):46-53.
2009: Stewart Juhani Akseli; Kampman Olli; Huuhka Martti; Anttila Sami; Huuhka Kaija; Lehtimäki Terho; Leinonen Esa
ACE polymorphism and response to electroconvulsive therapy in major depression.
Neuroscience letters 2009;458(3):122-5.
2009: Hilli Johanna; Heikkinen Tuija; Rontu Riikka; Lehtimäki Terho; Kishida Ikuko; Aklillu Eleni; Bertilsson Leif; Vahlberg Tero; Laine Kari
MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2009;19(5):363-70.
2009: Sipilä Kalle; Moilanen Leena; Nieminen Tuomo; Reunanen Antti; Jula Antti; Salomaa Veikko; Kaaja Risto; Kukkonen-Harjula Katriina; Lehtimäki Terho; Kesäniemi Y Antero; Koivistoinen Teemu; Nieminen Markku S; Tuomilehto Jaakko; Kähönen Mika
Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey.
Atherosclerosis 2009;204(1):276-81.
2009: Järvisalo M J; Hutri-Kähönen N; Juonala M; Mikkilä V; Räsänen L; Lehtimäki T; Viikari J; Raitakari O T
Breast feeding in infancy and arterial endothelial function later in life. The Cardiovascular Risk in Young Finns Study.
European journal of clinical nutrition 2009;63(5):640-5.
2009: Kiviniemi Tuomas O; Saraste Antti; Lehtimäki Terho; Toikka Jyri O; Saraste Markku; Raitakari Olli T; Pärkkä Jussi P; Hartiala Jaakko J; Viikari Jorma; Koskenvuo Juha W
High dose of red wine elicits enhanced inhibition of fibrinolysis.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2009;16(2):161-3.
2009: Minkkinen Mikko; Kähönen Mika; Viik Jari; Nikus Kjell; Lehtimäki Terho; Lehtinen Rami; Kööbi Tiit; Turjanmaa Väinö; Kaiser Willi; Verrier Richard L; Nieminen Tuomo
Enhanced predictive power of quantitative TWA during routine exercise testing in the Finnish Cardiovascular Study.
Journal of cardiovascular electrophysiology 2009;20(4):408-15.
2009: Hakanen Maarit; Raitakari Olli T; Lehtimäki Terho; Peltonen Nina; Pahkala Katja; Sillanmäki Lauri; Lagström Hanna; Viikari Jorma; Simell Olli; Rönnemaa Tapani
FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity.
The Journal of clinical endocrinology and metabolism 2009;94(4):1281-7.
2009: Jylhävä Juulia; Eklund Carita; Jylhä Marja; Hervonen Antti; Lehtimäki Terho; Karhunen Pekka; Hurme Mikko
Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study.
Experimental gerontology 2009;44(4):297-9.
2009: Hulkkonen Janne; Lehtimäki Terho; Mononen Nina; Juonala Markus; Hutri-Kähönen Nina; Taittonen Leena; Marniemi Jukka; Nieminen Tuomo; Viikari Jorma; Raitakari Olli; Kähönen Mika
Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2009;203(2):454-8.
2009: Keltikangas-Järvinen Liisa; Pulkki-Råback Laura; Elovainio Marko; Raitakari Olli T; Viikari Jorma; Lehtimäki Terho
DRD2 C32806T modifies the effect of child-rearing environment on adulthood novelty seeking.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(3):389-94.
2009: Slawnych Michael P; Nieminen Tuomo; Kähönen Mika; Kavanagh Katherine M; Lehtimäki Terho; Ramadan Darlene; Viik Jari; Aggarwal Sandeep G; Lehtinen Rami; Ellis Linda; Nikus Kjell; Exner Derek V;
Post-exercise assessment of cardiac repolarization alternans in patients with coronary artery disease using the modified moving average method.
Journal of the American College of Cardiology 2009;53(13):1130-7.
2009: Pessi T; Eklund C; Huhtala H; Raitakari O T; Juonala M; Kähönen M; Viikari J S A; Lehtimäki T; Hurme M
CRP and FCGR2A genes have an epistatic effect on carotid artery intima-media thickness: the Cardiovascular Risk in Young Finns Study.
International journal of immunogenetics 2009;36(1):39-45.
2009: Viljanen Antti P M; Iozzo Patricia; Borra Ronald; Kankaanpää Mikko; Karmi Anna; Lautamäki Riikka; Järvisalo Mikko; Parkkola Riitta; Rönnemaa Tapani; Guiducci Letizia; Lehtimäki Terho; Raitakari Olli T; Mari Andrea; Nuutila Pirjo
Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance.
The Journal of clinical endocrinology and metabolism 2009;94(1):50-5.
2008: Rinta Sanna; Kuusisto Hanna; Raunio Minna; Paalavuo Raija; Levula Mari; Lehtimäki Terho; Elovaara Irina
Apoptosis-related molecules in blood in multiple sclerosis.
Journal of neuroimmunology 2008;205(1-2):135-41.
2008: Nikkari Seppo T; Henttonen Antti; Kunnas Tarja; Kähönen Mika; Hutri-Kähönen Nina; Juonala Markus; Marniemi Jukka; Viikari Jorma; Raitakari Olli T; Lehtimäki Terho
Estrogen receptor 2 polymorphism and carotid intima-media thickness.
Genetic testing 2008;12(4):537-40.
2008: Huuhka Kaija; Anttila Sami; Huuhka Martti; Hietala Jarmo; Huhtala Heini; Mononen Nina; Lehtimäki Terho; Leinonen Esa
Dopamine 2 receptor C957T and catechol-o-methyltransferase Val158Met polymorphisms are associated with treatment response in electroconvulsive therapy.
Neuroscience letters 2008;448(1):79-83.
2008: Raitakari Olli T; Juonala Markus; Rönnemaa Tapani; Keltikangas-Järvinen Liisa; Räsänen Leena; Pietikäinen Matti; Hutri-Kähönen Nina; Taittonen Leena; Jokinen Eero; Marniemi Jukka; Jula Antti; Telama Risto; Kähönen Mika; Lehtimäki Terho; Akerblom Hans K; Viikari Jorma S A
Cohort profile: the cardiovascular risk in Young Finns Study.
International journal of epidemiology 2008;37(6):1220-6.
2008: Salminen Marika; Lehtimäki Terho; Fan Yue-Mei; Vahlberg Tero; Kivelä Sirkka-Liisa
Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene and changes in serum lipids during a family-based counselling intervention among school-aged children with a family history of CVD.
Public health nutrition 2008;11(11):1156-62.
2008: Lehtimäki Terho; Hutri-Kähönen Nina; Kähönen Mika; Hemminki Jukka; Mikkilä Vera; Laaksonen Marika; Räsänen Leena; Mononen Nina; Juonala Markus; Marniemi Jukka; Viikari Jorma; Raitakari Olli
Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study.
Clinical science (London, England : 1979) 2008;115(9):265-71.
2008: Nieminen Tuomo; Kähönen Mika; Viiri Leena E; Grönroos Paula; Lehtimäki Terho
Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease.
Pharmacogenomics 2008;9(10):1475-86.
2008: Kivimäki Mika; Smith George Davey; Timpson Nic J; Lawlor Debbie A; Batty G David; Kähönen Mika; Juonala Markus; Rönnemaa Tapani; Viikari Jorma S A; Lehtimäki Terho; Raitakari Olli T
Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study.
European heart journal 2008;29(20):2552-60.
2008: Tobin Martin D; Kähönen Mika; Braund Peter; Nieminen Tuomo; Hajat Cother; Tomaszewski Maciej; Viik Jari; Lehtinen Rami; Ng G Andre; Macfarlane Peter W; Burton Paul R; Lehtimäki Terho; Samani Nilesh J
Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations.
International journal of epidemiology 2008;37(5):1132-41.
2008: Samani Nilesh J; Raitakari Olli T; Sipilä Kalle; Tobin Martin D; Schunkert Heribert; Juonala Markus; Braund Peter S; Erdmann Jeanette; Viikari Jorma; Moilanen Leena; Taittonen Leena; Jula Antti; Jokinen Eero; Laitinen Tomi; Hutri-Kähönen Nina; Nieminen Markku S; Kesäniemi Y Antero; Hall Alistair S; Hulkkonen Janne; Kähönen Mika; Lehtimäki Terho
Coronary artery disease-associated locus on chromosome 9p21 and early markers of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(9):1679-83.
2008: Miettinen Tatu A; Gylling Helena; Viikari Jorma; Lehtimäki Terho; Raitakari Olli T
Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study.
Atherosclerosis 2008;200(1):177-83.
2008: Lee Jenny C; Weissglas-Volkov Daphna; Kyttälä Mira; Dastani Zari; Cantor Rita M; Sobel Eric M; Plaisier Christopher L; Engert James C; van Greevenbroek Marleen M J; Kane John P; Malloy Mary J; Pullinger Clive R; Huertas-Vazquez Adriana; Aguilar-Salinas Carlos A; Tusie-Luna Teresa; de Bruin Tjerk W A; Aouizerat Bradley E; van der Kallen Carla C J; Croce Carlo M; Aqeilan Rami I; Marcil Michel; Viikari Jorma S A; Lehtimäki Terho; Raitakari Olli T; Kuusisto Johanna; Laakso Markku; Taskinen Marja-Riitta; Genest Jacques; Pajukanta Päivi
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.
American journal of human genetics 2008;83(2):180-92.
2008: Koskela Jenni; Kähönen Mika; Fan Meng; Nieminen Tuomo; Lehtinen Rami; Viik Jari; Nikus Kjell; Niemelä Kari; Kööbi Tiit; Turjanmaa Väinö; Pörsti Ilkka; Lehtimäki Terho
Effect of common KCNE1 and SCN5A ion channel gene variants on T-wave alternans, a marker of cardiac repolarization, during clinical exercise stress test: the Finnish Cardiovascular Study.
Translational research : the journal of laboratory and clinical medicine 2008;152(2):49-58.
2008: Päivä Hannu; Kähönen Mika; Lehtimäki Terho; Raitakari Olli T; Jula Antti; Viikari Jorma; Alfthan Georg; Juonala Markus; Laaksonen Reijo; Hutri-Kähönen Nina
Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.
American journal of hypertension 2008;21(8):873-8.
2008: Nieminen T; Leino J; Maanoja J; Nikus K; Viik J; Lehtimäki T; Kööbi T; Lehtinen R; Niemelä K; Turjanmaa V; Kähönen M
The prognostic value of haemodynamic parameters in the recovery phase of an exercise test. The Finnish Cardiovascular Study.
Journal of human hypertension 2008;22(8):537-43.
2008: Ilveskoski Erkki; Viiri Leena E; Mikkelsson Jussi; Pörsti Ilkka; Lehtimäki Terho; Karhunen Pekka J
Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study.
Atherosclerosis 2008;199(2):445-50.
2008: Hintsanen Mirka; Elovainio Marko; Puttonen Sampsa; Kivimäki Mika; Lehtimäki Terho; Kähönen Mika; Juonala Markus; Rontu Riikka; Viikari Jorma S A; Raitakari Olli T; Keltikangas-Järvinen Liisa
Val/Met polymorphism of the COMT gene moderates the association between job strain and early atherosclerosis in young men.
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2008;50(6):649-57.
2008: Huuhka Kaija; Kampman Olli; Anttila Sami; Huuhka Martti; Rontu Riikka; Mattila Kari M; Hurme Mikko; Lehtimäki Terho; Leinonen Esa
RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder.
Neuroscience letters 2008;437(1):25-8.
2008: Mäkelä Riikka; Loimaala Antti; Nenonen Arja; Mercuri Michele; Vuori Ilkka; Huhtala Heini; Oja Pekka; Bond Gene; Koivula Timo; Lehtimäki Terho
The association of myeloperoxidase promoter polymorphism with carotid atherosclerosis is abolished in patients with type 2 diabetes.
Clinical biochemistry 2008;41(7-8):532-7.
2008: Kristiansson Kati; Ilveskoski Erkki; Lehtimäki Terho; Peltonen Leena; Perola Markus; Karhunen Pekka J
Association analysis of allelic variants of USF1 in coronary atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):983-9.
2008: Berthold H K; Laaksonen R; Lehtimäki T; Gylling H; Krone W; Gouni-Berthold I
SREBP-1c gene polymorphism is associated with increased inhibition of cholesterol-absorption in response to ezetimibe treatment.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2008;116(5):262-7.
2008: Hernesniemi Jussi A; Raitakari Olli T; Kähönen Mika; Juonala Markus; Hutri-Kähönen Nina; Marniemi Jukka; Viikari Jorma; Lehtimäki Terho
Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study.
Atherosclerosis 2008;198(1):152-9.
2008: Gimeno D; Ferrie J E; Elovainio M; Pulkki-Raback L; Keltikangas-Jarvinen L; Eklund C; Hurme M; Lehtimäki T; Marniemi J; Viikari J S A; Raitakari O T; Kivimäki M
When do social inequalities in C-reactive protein start? A life course perspective from conception to adulthood in the Cardiovascular Risk in Young Finns Study.
International journal of epidemiology 2008;37(2):290-8.
2008: Anttila Sami; Huuhka Kaija; Huuhka Martti; Illi Ari; Rontu Riikka; Leinonen Esa; Lehtimäki Terho
Catechol-O-methyltransferase (COMT) polymorphisms predict treatment response in electroconvulsive therapy.
The pharmacogenomics journal 2008;8(2):113-6.
2008: Siirtola Arja; Virtanen Suvi M; Ala-Houhala Marja; Koivisto Anna-Maija; Solakivi Tiina; Lehtimäki Terho; Holmberg Christer; Antikainen Marjatta; Salo Matti K
Diet does not explain the high prevalence of dyslipidaemia in paediatric renal transplant recipients.
Pediatric nephrology (Berlin, Germany) 2008;23(2):297-305.
2008: Hänninen Kari; Katila Heikki; Saarela Marika; Rontu Riikka; Mattila Kari M; Fan Meng; Hurme Mikko; Lehtimäki Terho
Interleukin-1 beta gene polymorphism and its interactions with neuregulin-1 gene polymorphism are associated with schizophrenia.
European archives of psychiatry and clinical neuroscience 2008;258(1):10-5.
2008: Hernesniemi Jussi A; Karhunen Pekka J; Rontu Riikka; Ilveskoski Erkki; Kajander Olli; Goebeler Sirkka; Viiri Leena E; Pessi Tanja; Hurme Mikko; Lehtimäki Terho
Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study.
Atherosclerosis 2008;196(2):643-9.
2008: Keltikangas-Järvinen L; Puttonen S; Kivimäki M; Elovainio M; Pulkki-Råback L; Koivu M; Rontu R; Lehtimäki T
Serotonin receptor genes 5HT1A and 5HT2A modify the relation between childhood temperament and adulthood hostility.
Genes, brain, and behavior 2008;7(1):46-52.
2008: Eklund C; Kivimäki M; Islam Md Shaheenul; Juonala M; Kähönen M; Marniemi J; Lehtimäki T; Viikari J; Raitakari O T; Hurme M
C-reactive protein genetics is associated with carotid artery compliance in men in The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2008;196(2):841-8.
2008: Grönroos Paula; Raitakari Olli T; Kähönen Mika; Hutri-Kähönen Nina; Juonala Markus; Marniemi Jukka; Viikari Jorma; Lehtimäki Terho
Relation of apolipoprotein E polymorphism to markers of early atherosclerotic changes in young adults--the Cardiovascular Risk in Young Finns Study.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(1):29-34.
2008: Fan Yue-Mei; Karhunen Pekka J; Levula Mari; Ilveskoski Erkki; Mikkelsson Jussi; Kajander Olli A; Järvinen Otso; Oksala Niku; Thusberg Janita; Vihinen Mauno; Salenius Juha-Pekka; Kytömäki Leena; Soini Juhani T; Laaksonen Reijo; Lehtimäki Terho
Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.
Thrombosis journal 2008;6():17.
2008: Service Helena M; Hintsanen Mirka; Hintsa Taina; Lehtimäki Terho; Raitakari Olli T; Viikari Jorma S; Keltikangas-Järvinen Liisa
Does neuregulin-1 play a role in Type A behavior? The cardiovascular risk in young Finns study.
Behavioral and brain functions : BBF 2008;4():40.
2008: Kiviniemi Tuomas O; Saraste Antti; Toikka Jyri O; Saraste Markku; Raitakari Olli T; Pärkkä Jussi P; Lehtimäki Terho; Hartiala Jaakko J; Viikari Jorma; Koskenvuo Juha W
Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men.
Cardiovascular ultrasound 2008;6():25.
2008: Grönroos Paula; Raitakari Olli T; Kähönen Mika; Hutri-Kähönen Nina; Marniemi Jukka; Viikari Jorma; Lehtimäki Terho
Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: the Cardiovascular Risk in Young Finns Study.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(2):179-86.
2008: Collings A; Raitakari O T; Juonala M; Rontu R; Kähönen M; Hutri-Kähönen N; Rönnemaa T; Marniemi J; Viikari J S A; Lehtimäki T
Associations of methylenetetrahydrofolate reductase C677T polymorphism with markers of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.
Scandinavian journal of clinical and laboratory investigation 2008;68(1):22-30.
2008: Koskela J; Laiho J; KäHönen M; Rontu R; Lehtinen R; Viik J; Niemi M; Niemelä K; Kööbi T; Turjanmaa V; Pörsti I; Lehtimäki T; Nieminen T
Potassium channel KCNH2 K897T polymorphism and cardiac repolarization during exercise test: The Finnish Cardiovascular Study.
Scandinavian journal of clinical and laboratory investigation 2008;68(1):31-8.
2007: Viikari Liisa A; Huupponen Risto K; Viikari Jorma S A; Marniemi Jukka; Eklund Carita; Hurme Mikko; Lehtimäki Terho; Kivimäki Mika; Raitakari Olli T
Relationship between leptin and C-reactive protein in young Finnish adults.
The Journal of clinical endocrinology and metabolism 2007;92(12):4753-8.
2007: Kiviniemi Tuomas O; Saraste Antti; Toikka Jyri O; Saraste Markku; Raitakari Olli T; Pärkkä Jussi P; Lehtimäki Terho; Hartiala Jaakko J; Viikari Jorma; Koskenvuo Juha W
A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserve.
Atherosclerosis 2007;195(2):e176-81.
2007: Keltikangas-Järvinen Liisa; Elovainio Marko; Kivimäki Mika; Raitakari Olli T; Viikari Jorma S A; Lehtimäki Terho
Dopamine receptor D2 gene Taq1A (C32806T) polymorphism modifies the relationship between birth weight and educational attainment in adulthood: 21-year follow-up of the Cardiovascular Risk in Young Finns study.
Pediatrics 2007;120(4):756-61.
2007: Virtanen Matti; Kähönen Mika; Nieminen Tuomo; Karjalainen Pasi; Tarvainen Mika; Lehtimäki Terho; Lehtinen Rami; Nikus Kjell; Kööbi Tiit; Niemi Mari; Niemelä Kari; Turjanmaa Väinö; Malmivuo Jaakko; Viik Jari
Heart rate variability derived from exercise ECG in the detection of coronary artery disease.
Physiological measurement 2007;28(10):1189-200.
2007: Hemminki Virpi; Laakso Juha; Kähönen Mika; Turjanmaa Väinö; Uusitalo Hannu; Lehtimäki Terho; Ruokonen Inkeri; Laaksonen Reijo; Huhtala Heini; Päivä Hannu
Plasma asymmetric dimethylarginine and retinal vessel diameters in middle-aged men.
Metabolism: clinical and experimental 2007;56(10):1305-10.
2007: Hurme M; Kivimäki M; Pertovaara M; Lehtimäki T; Karhunen P J; Jylhä M; Hervonen A; Eklund C
CRP gene is involved in the regulation of human longevity: a follow-up study in Finnish nonagenarians.
Mechanisms of ageing and development 2007;128(10):574-6.
2007: Nieminen Tuomo; Lehtimäki Terho; Viik Jari; Lehtinen Rami; Nikus Kjell; Kööbi Tiit; Niemelä Kari; Turjanmaa Väinö; Kaiser Willi; Huhtala Heini; Verrier Richard L; Huikuri Heikki; Kähönen Mika
T-wave alternans predicts mortality in a population undergoing a clinically indicated exercise test.
European heart journal 2007;28(19):2332-7.
2007: Kivimäki Mika; Lawlor Debbie A; Smith George Davey; Eklund Carita; Hurme Mikko; Lehtimäki Terho; Viikari Jorma S A; Raitakari Olli T
Variants in the CRP gene as a measure of lifelong differences in average C-reactive protein levels: the Cardiovascular Risk in Young Finns Study, 1980-2001.
American journal of epidemiology 2007;166(7):760-4.
2007: Jokela Markus; Lehtimäki Terho; Keltikangas-Järvinen Liisa
The influence of urban/rural residency on depressive symptoms is moderated by the serotonin receptor 2A gene.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):918-22.
2007: Jylhä Marja; Paavilainen Paula; Lehtimäki Terho; Goebeler Sirkka; Karhunen Pekka J; Hervonen Antti; Hurme Mikko
Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(9):1016-21.
2007: Nieminen Tuomo; Knuuti Juhani; Hämelahti Päivi; Kähönen Mika; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Jokela Hannu; Lehtimäki Terho
Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy.
Vascular pharmacology 2007;47(2-3):113-7.
2007: Lautamäki Riikka; Rönnemaa Tapani; Huupponen Risto; Lehtimäki Terho; Iozzo Patricia; Airaksinen K E Juhani; Knuuti Juhani; Nuutila Pirjo
Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease.
Metabolism: clinical and experimental 2007;56(7):881-6.
2007: Nieminen Tuomo; Matinheikki Jussi; Nenonen Arja; Kukkonen-Harjula Katriina; Lindi Virpi; Hämelahti Päivi; Laaksonen Reijo; Fan Yue-Mei; Kähönen Mika; Fogelholm Mikael; Lehtimäki Terho
The relationship of sterol regulatory element-binding protein cleavage-activation protein and apolipoprotein E gene polymorphisms with metabolic changes during weight reduction.
Metabolism: clinical and experimental 2007;56(7):876-80.
2007: Fan Meng; Raitakari Olli T; Kähönen Mika; Juonala Markus; Hutri-Kähönen Nina; Marniemi Jukka; Rontu Riikka; Pörsti Ilkka; Viikari Jorma; Lehtimäki Terho
CYBA C242T gene polymorphism and flow-mediated vasodilation in a population of young adults: the Cardiovascular Risk in Young Finns Study.
Journal of hypertension 2007;25(7):1381-7.
2007: Jokela Markus; Lehtimäki Terho; Keltikangas-Järvinen Liisa
The serotonin receptor 2A gene moderates the influence of parental socioeconomic status on adulthood harm avoidance.
Behavior genetics 2007;37(4):567-74.
2007: Elovainio Marko; Jokela Markus; Kivimäki Mika; Pulkki-Råback Laura; Lehtimäki Terho; Airla Nina; Keltikangas-Järvinen Liisa
Genetic variants in the DRD2 gene moderate the relationship between stressful life events and depressive symptoms in adults: cardiovascular risk in young Finns study.
Psychosomatic medicine 2007;69(5):391-5.
2007: Fan Y M; Lehtimäki T; Rontu R; Ilveskoski E; Goebeler S; Kajander O; Mikkelsson J; Viiri L E; Perola M; Karhunen P J
The hepatic lipase gene C-480T polymorphism in the development of early coronary atherosclerosis: the Helsinki Sudden Death Study.
European journal of clinical investigation 2007;37(6):472-7.
2007: Illi Ari; Kampman Olli; Hänninen Kari; Anttila Sami; Mattila Kari M; Katila Heikki; Rontu Riikka; Hurme Mikko; Lehtimäki Terho; Leinonen Esa
Catechol-O-methyltransferase val108/158met genotype and response to antipsychotic medication in schizophrenia.
Human psychopharmacology 2007;22(4):211-5.
2007: Jokela Markus; Räikkönen Katri; Lehtimäki Terho; Rontu Riikka; Keltikangas-Järvinen Liisa
Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adults.
Journal of affective disorders 2007;100(1-3):191-7.
2007: Keltikangas-Järvinen L; Puttonen Sampsa; Kivimäki Mika; Elovainio Marko; Rontu Riikka; Lehtimäki Terho
Tryptophan hydroxylase 1 gene haplotypes modify the effect of a hostile childhood environment on adulthood harm avoidance.
Genes, brain, and behavior 2007;6(4):305-13.
2007: Fan Yue-Mei; Lehtimäki Terho; Rontu Riikka; Ilveskoski Erkki; Goebeler Sirkka; Kajander Olli; Mikkelsson Jussi; Perola Markus; Karhunen Pekka J
Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study.
Atherosclerosis 2007;192(2):421-7.
2007: Hurme M; Korkki S; Lehtimäki T; Karhunen P J; Jylhä M; Hervonen A; Pertovaara M
Autoimmunity and longevity: presence of antinuclear antibodies is not associated with the rate of inflammation or mortality in nonagenarians.
Mechanisms of ageing and development 2007;128(5-6):407-8.
2007: Nieminen Tuomo; Kähönen Mika; Islam Shaheenul; Raitakari Olli T; Hutri-Kähönen Nina; Marniemi Jukka; Juonala Markus; Rontu Riikka; Viikari Jorma; Lehtimäki Terho
Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms do not affect early functional and structural changes in atherosclerosis: the Cardiovascular Risk in Young Finns study.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(5):741-5.
2007: Schick B A; Laaksonen R; Frohlich J J; Päivä H; Lehtimäki T; Humphries K H; Côté H C F
Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin.
Clinical pharmacology and therapeutics 2007;81(5):650-3.
2007: Kivimäki Mika; Lawlor Debbie A; Eklund Carita; Smith George Davey; Hurme Mikko; Lehtimäki Terho; Viikari Jorma S A; Raitakari Olli T
Mendelian randomization suggests no causal association between C-reactive protein and carotid intima-media thickness in the young Finns study.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):978-9.
2007: Pertovaara M; Raitala A; Juonala M; Lehtimäki T; Huhtala H; Oja S S; Jokinen E; Viikari J S A; Raitakari O T; Hurme M
Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study.
Clinical and experimental immunology 2007;148(1):106-11.
2007: Wegiel Jerzy; Kuchna Izabela; Nowicki Krzysztof; Frackowiak Janusz; Mazur-Kolecka Bozena; Imaki Humi; Wegiel Jarek; Mehta Pankaj D; Silverman Wayne P; Reisberg Barry; Deleon Mony; Wisniewski Thomas; Pirttilla Tuula; Frey Harry; Lehtimäki Terho; Kivimäki Tarmo; Visser Frank E; Kamphorst Wouter; Potempska Anna; Bolton David; Currie Julia R; Miller David L
Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration.
Acta neuropathologica 2007;113(4):389-402.
2007: Jokela Markus; Keltikangas-Järvinen Liisa; Kivimäki Mika; Puttonen Sampsa; Elovainio Marko; Rontu Riikka; Lehtimäki Terho
Serotonin receptor 2A gene and the influence of childhood maternal nurturance on adulthood depressive symptoms.
Archives of general psychiatry 2007;64(3):356-60.
2007: Lehtimäki Terho; Hervonen Antti; Rontu Riikka; Karhunen Pekka; Jylhä Marja; Hurme Mikko
Survival related to plasma C-reactive-protein in nonagenarians is modified by apolipoprotein E genotype.
Clinical chemistry 2007;53(2):365-7.
2007: Pertovaara M; Raitala A; Juonala M; Kähönen M; Lehtimäki T; Viikari J S A; Raitakari O T; Hurme M
Autoimmunity and atherosclerosis: functional polymorphism of PTPN22 is associated with phenotypes related to the risk of atherosclerosis. The Cardiovascular Risk in Young Finns Study.
Clinical and experimental immunology 2007;147(2):265-9.
2007: Hänninen Kari; Katila Heikki; Anttila Sami; Rontu Riikka; Maaskola Julius; Hurme Mikko; Lehtimäki Terho
Epidermal growth factor a61g polymorphism is associated with the age of onset of schizophrenia in male patients.
Journal of psychiatric research 2007;41(1-2):8-14.
2007: Puttonen Sampsa; Keltikangas-Järvinen Liisa; Elovainio Marko; Kivimäki Mika; Rontu Riikka; Lehtimäki Terho
Temperamental activity and epidermal growth factor A61G polymorphism in Finnish adults.
Neuropsychobiology 2007;56(4):208-12.
2007: Ilveskoski E; Lehtimäki T; Laaksonen R; Janatuinen T; Vesalainen R; Nuutila P; Laippala P; Karhunen P J; Knuuti J
Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype.
Scandinavian journal of clinical and laboratory investigation 2007;67(7):723-34.
2007: Michou Sanna-Maria; Kähönen Mika; Lehtimäki Terho; Nikus Kjell; Viik Jari; Niemelä Kari; Kallio Janne; Lehtinen Rami; Kööbi Tiit; Turjanmaa Väinö; Nieminen Tuomo
Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting.
Clinical drug investigation 2007;27(10):673-81.
2007: Anttila Sami; Kampman Olli; Illi Ari; Rontu Riikka; Lehtimäki Terho; Leinonen Esa
Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach.
BMC psychiatry 2007;7():22.
2007: Grönroos Paula; Raitakari Olli T; Kähönen Mika; Hutri-Kähönen Nina; Marniemi Jukka; Viikari Jorma; Lehtimäki Terho
Influence of apolipoprotein E polymorphism on serum lipid and lipoprotein changes: a 21-year follow-up study from childhood to adulthood. The Cardiovascular Risk in Young Finns Study.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2007;45(5):592-8.
2007: Anttila S; Huuhka K; Huuhka M; Rontu R; Hurme M; Leinonen E; Lehtimäki T
Interaction between 5-HT1A and BDNF genotypes increases the risk of treatment-resistant depression.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(8):1065-8.
2007: Nieminen T; Lehtimäki T; Mäenpää J; Ropo A; Uusitalo H; Kähönen M
Ophthalmic timolol: plasma concentration and systemic cardiopulmonary effects.
Scandinavian journal of clinical and laboratory investigation 2007;67(2):237-45.
2007: Luomala M; Laaksonen R; Janatuinen T; Vesalainen R; Nuutila P; Saarela M; Mattila K; Kalijärvi M; Solakivi T; Knuuti J; Hurme M; Lehtimäki T
High plasma levels of CD40 are associated with low coenzyme Q and vitamin E content of low-density lipoprotein in healthy men.
Scandinavian journal of clinical and laboratory investigation 2007;67(2):115-22.
2007: Anttila S; Huuhka K; Huuhka M; Rontu R; Mattila K M; Leinonen E; Lehtimäki T
Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(4):461-8.
2006: Lehtimäki Terho; Hemminki Jukka; Rontu Riikka; Mikkilä Vera; Räsänen Leena; Laaksonen Marika; Hutri-Kähönen Nina; Kähönen Mika; Viikari Jorma; Raitakari Olli
The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study--the Cardiovascular Risk in Young Finns Study.
Pediatrics 2006;118(4):1553-9.
2006: Luomala Mari; Päivä Hannu; Laaksonen Reijo; Thelen Karin; Lütjohann Dieter; Peltonen Nina; Lehtimäki Terho
Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia.
Scandinavian cardiovascular journal : SCJ 2006;40(5):280-4.
2006: Salminen Marika; Lehtimäki Terho; Fan Yue-Mei; Vahlberg Tero; Kivelä Sirkka-Liisa
Apolipoprotein E polymorphism and changes in serum lipids during a family-based counselling intervention.
Public health nutrition 2006;9(7):859-65.
2006: Hänninen Kari; Katila Heikki; Kampman Olli; Anttila Sami; Illi Ari; Rontu Riikka; Mattila Kari M; Hietala Jarmo; Hurme Mikko; Leinonen Esa; Lehtimäki Terho
Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia.
Neuroscience letters 2006;407(3):195-8.
2006: Kampman O; Illi A; Hänninen K; Katila H; Anttila S; Rontu R; Mattila K M; Leinonen E; Lehtimäki T
RGS4 genotype is not associated with antipsychotic medication response in schizophrenia.
Journal of neural transmission (Vienna, Austria : 1996) 2006;113(10):1563-8.
2006: Islam Md Shaheenul; Lehtimäki Terho; Juonala Markus; Kähönen Mika; Hutri-Kähönen Nina; Kainulainen Katariina; Miettinen Helena; Taittonen Leena; Kontula Kimmo; Viikari Jorma S A; Raitakari Olli T
Polymorphism of the angiotensin-converting enzyme (ACE) and angiotesinogen (AGT) genes and their associations with blood pressure and carotid artery intima media thickness among healthy Finnish young adults--the Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2006;188(2):316-22.
2006: Loimaala Antti; Rontu Riikka; Vuori Ilkka; Mercuri Michele; Lehtimäki Terho; Nenonen Arja; Bond M Gene
Blood leukocyte count is a risk factor for intima-media thickening and subclinical carotid atherosclerosis in middle-aged men.
Atherosclerosis 2006;188(2):363-9.
2006: Fan Yue-Mei; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Laine Hanna; Raitakari Olli T; Nuutila Pirjo; Knuuti Juhani; Rontu Riikka; Lehtimäki Terho
The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.
Atherosclerosis 2006;188(2):391-7.
2006: Fan Meng; Kähönen Mika; Rontu Riikka; Lehtinen Rami; Viik Jari; Niemi Mari; Nieminen Tuomo; Niemelä Kari; Pörsti Ilkka; Kööbi Tiit; Turjanmaa Väinö; Lehtimäki Terho
The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study.
American heart journal 2006;152(3):538-42.
2006: Päivä Hannu; Laakso Juha; Ruokonen Inkeri; Luomala Mari; Saarela Marika; Solakivi Tiina; Metso Saara; Nikkilä Matti; Wuolijoki Erkki; Laaksonen Reijo; Lehtimäki Terho
Plasma asymmetric dimethylarginine (ADMA), nitrate and the indices of low-density lipoprotein oxidation.
Clinica chimica acta; international journal of clinical chemistry 2006;371(1-2):97-101.
2006: Lautamäki Riikka; Borra Ronald; Iozzo Patricia; Komu Markku; Lehtimäki Terho; Salmi Marko; Jalkanen Sirpa; Airaksinen K E Juhani; Knuuti Juhani; Parkkola Riitta; Nuutila Pirjo
Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes.
American journal of physiology. Endocrinology and metabolism 2006;291(2):E282-90.
2006: Thelen Karin M; Laaksonen Reijo; Päivä Hannu; Lehtimäki Terho; Lütjohann Dieter
High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels.
Journal of clinical pharmacology 2006;46(7):812-6.
2006: Eklund Carita; Nenonen Arja; Kukkonen-Harjula Katriina; Borg Patrik; Fogelholm Mikael; Laine Seppo; Huhtala Heini; Lehtimäki Terho; Hurme Mikko
Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men.
European cytokine network 2006;17(2):131-5.
2006: Päivä Hannu; Laakso Juha; Kähönen Mika; Turjanmaa Väinö; Kööbi Tiit; Majahalme Silja; Lehtimäki Terho; Ruokonen Inkeri; Laaksonen Reijo
Asymmetric dimethylarginine and hemodynamic regulation in middle-aged men.
Metabolism: clinical and experimental 2006;55(6):771-7.
2006: Viiri Leena E; Raitakari Olli T; Huhtala Heini; Kähönen Mika; Rontu Riikka; Juonala Markus; Hutri-Kähönen Nina; Marniemi Jukka; Viikari Jorma S A; Karhunen Pekka J; Lehtimäki Terho
Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults.
Journal of lipid research 2006;47(6):1298-306.
2006: Pertovaara M; Raitala A; Lehtimäki T; Karhunen P J; Oja S S; Jylhä M; Hervonen A; Hurme M
Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality.
Mechanisms of ageing and development 2006;127(5):497-9.
2006: Järvisalo Mikko J; Jartti Laura; Marniemi Jukka; Rönnemaa Tapani; Viikari Jorma S A; Lehtimäki Terho; Raitakari Olli T
Determinants of short-term variation in arterial flow-mediated dilatation in healthy young men.
Clinical science (London, England : 1979) 2006;110(4):475-82.
2006: Kalela Anne; Jokela Hannu; Lehtimäki Terho; Uppa Helena; Kunnas Tarja; Teisala Klaus; Punnonen Reijo; Nikkari Seppo T
Effect of the cessation of long-term hormone replacement therapy on plasma plasminogen activator inhibitor-1 and fibrinogen.
European journal of obstetrics, gynecology, and reproductive biology 2006;125(2):217-20.
2006: Nieminen Tuomo; Kähönen Mika; Lehtimäki Terho
The effects of apoA-I/C-III/A-IV, apoE and apoB polymorphisms on carotid artery intima-media thickness.
Future cardiology 2006;2(2):179-86.
2006: Rontu Riikka; Ojala Petri; Hervonen Antti; Goebeler Sirkka; Karhunen Pekka J; Nikkilä Matti; Kunnas Tarja; Jylhä Marja; Eklund Carita; Hurme Mikko; Lehtimäki Terho
Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians.
Clinical endocrinology 2006;64(3):265-70.
2006: Elovaara I; Kuusisto H; Paalavuo R; Särkijärvi S; Lehtimäki T; Huhtala H; Vilpo J
Effect of high-dose methylprednisolone treatment on CCR5 expression on blood cells in MS exacerbation.
Acta neurologica Scandinavica 2006;113(3):163-6.
2006: Laaksonen Reijo; Thelen Karin M; Päivä Hannu; Matinheikki Jussi; Vesalainen Risto; Janatuinen Tuula; Knuuti Juhani; Rontu Riikka; von Bergmann Klaus; Lütjohann Dieter; Lehtimäki Terho
Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.
Atherosclerosis 2006;185(1):206-9.
2006: Siirtola Arja; Ketomäki Anna; Miettinen Tatu A; Gylling Helena; Lehtimäki Terho; Holmberg Christer; Salo Matti K; Antikainen Marjatta
Cholesterol absorption and synthesis in pediatric kidney, liver, and heart transplant recipients.
Transplantation 2006;81(3):327-34.
2006: Keltikangas-Järvinen L; Puttonen S; Kivimäki M; Rontu R; Lehtimäki T
Cloninger's temperament dimensions and epidermal growth factor A61G polymorphism in Finnish adults.
Genes, brain, and behavior 2006;5(1):11-8.
2006: Nieminen Tuomo; Lehtimäki Terho; Laiho Jarno; Rontu Riikka; Niemelä Kari; Kööbi Tiit; Lehtinen Rami; Viik Jari; Turjanmaa Väinö; Kähönen Mika
Effects of polymorphisms in beta1-adrenoceptor and alpha-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(2):507-11.
2006: Thelen Karin M; Lütjohann Dieter; Vesalainen Risto; Janatuinen Tuula; Knuuti Juhani; von Bergmann Klaus; Lehtimäki Terho; Laaksonen Reijo
Effect of pravastatin on plasma sterols and oxysterols in men.
European journal of clinical pharmacology 2006;62(1):9-14.
2006: Laaksonen Reijo; Katajamaa Mikko; Päivä Hannu; Sysi-Aho Marko; Saarinen Lilli; Junni Päivi; Lütjohann Dieter; Smet Joél; Van Coster Rudy; Seppänen-Laakso Tuulikki; Lehtimäki Terho; Soini Juhani; Oresic Matej
A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle.
PloS one 2006;1():e97.
2006: Hernesniemi J; Lehtimäki T; Rontu R; Islam M S; Eklund C; Mikkelsson J; Ilveskoski E; Kajander O; Goebeler S; Viiri L E; Hurme M; Karhunen P J
Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions.
Scandinavian journal of clinical and laboratory investigation 2006;66(8):667-75.
2006: Levula M; Jaakkola O; Luomala M; Nikkari S T; Lehtimäki T
Effects of oxidized low- and high-density lipoproteins on gene expression of human macrophages.
Scandinavian journal of clinical and laboratory investigation 2006;66(6):497-508.
2006: Mäkelä R; Dastidar P; Jokela H; Jaakkola O; Saarela M; Punnonen R; Lehtimäki T
Relation of myeloperoxidase promoter polymorphism and long-term hormone replacement therapy to oxidized low-density lipoprotein autoantibodies in postmenopausal women.
Scandinavian journal of clinical and laboratory investigation 2006;66(5):371-83.
2006: Leskinen Yrjö; Groundstroem Kaj; Virtanen Vesa; Lehtimäki Terho; Huhtala Heini; Saha Heikki
Prediction of coronary artery disease by transesophageal echocardiographic detection of thoracic aortic plaque in patients with chronic kidney disease.
Nephron. Clinical practice 2006;103(4):c157-61.
2006: Nieminen Tuomo; Lehtinen Rami; Viik Jari; Lehtimäki Terho; Niemelä Kari; Nikus Kjell; Niemi Mari; Kallio Janne; Kööbi Tiit; Turjanmaa Väinö; Kähönen Mika
The Finnish Cardiovascular Study (FINCAVAS): characterising patients with high risk of cardiovascular morbidity and mortality.
BMC cardiovascular disorders 2006;6():9.
2006: Särkijärvi Silja; Kuusisto Hanna; Paalavuo Raija; Levula Mari; Airla Nina; Lehtimäki Terho; Kaprio Jaakko; Koskenvuo Markku; Elovaara Irina
Gene expression profiles in Finnish twins with multiple sclerosis.
BMC medical genetics 2006;7():11.
2006: Kalela A; Limnell V; Aittoniemi J; Virtanen V; Jaakkola O; Lehtimäki T; Nikkari S T
Serum matrix metalloproteinase-9 and venous bypass graft occlusion.
Scandinavian journal of clinical and laboratory investigation 2006;66(1):7-14.
2005: Jokela Hannu; Kalela Anne; Lilja Mari; Salmi Mia; Lehtimäki Terho; Kunnas Tarja; Teisala Klaus; Punnonen Reijo; Nikkari Seppo T
Sequentially combined estradiol valerate plus levonorgestrel therapy decreases 18:1 trans-fatty acid content of plasma lipids in healthy postmenopausal women.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2005;21(6):360-5.
2005: Nieminen Tuomo; Uusitalo Hannu; Mäenpää Jukka; Turjanmaa Väinö; Rane Anders; Lundgren Stefan; Ropo Auli; Rontu Riikka; Lehtimäki Terho; Kähönen Mika
Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study.
European journal of clinical pharmacology 2005;61(11):811-9.
2005: Nenonen Arja; Cheng Sulin; Ivaska Kaisa K; Alatalo Sari L; Lehtimäki Terho; Schmidt-Gayk Heinrich; Uusi-Rasi Kirsti; Heinonen Ari; Kannus Pekka; Sievänen Harri; Vuori Ilkka; Väänänen H Kalervo; Halleen Jussi M
Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(10):1804-12.
2005: Ainiala H; Dastidar P; Loukkola J; Lehtimäki T; Korpela M; Peltola J; Hietaharju A
Cerebral MRI abnormalities and their association with neuropsychiatric manifestations in SLE: a population-based study.
Scandinavian journal of rheumatology 2005;34(5):376-82.
2005: Lehtimäki Terho; Ojala Petri; Rontu Riikka; Goebeler Sirkka; Karhunen Pekka J; Jylhä Marja; Mattila Kari; Metso Saara; Jokela Hannu; Nikkilä Matti; Wuolijoki Erkki; Hervonen Antti; Hurme Mikko
Interleukin-6 modulates plasma cholesterol and C-reactive protein concentrations in nonagenarians.
Journal of the American Geriatrics Society 2005;53(9):1552-8.
2005: Hänninen Kari; Katila Heikki; Rontu Riikka; Mattila Kari M; Hurme Mikko; Lehtimäki Terho
Tumor necrosis factor-alpha --G308A polymorphism in schizophrenia in a Finnish population.
Neuroscience letters 2005;385(1):76-81.
2005: Eklund C; Lehtimäki T; Hurme M
Epistatic effect of C-reactive protein (CRP) single nucleotide polymorphism (SNP) +1059 and interleukin-1B SNP +3954 on CRP concentration in healthy male blood donors.
International journal of immunogenetics 2005;32(4):229-32.
2005: Lehtimäki Terho; Metso Saara; Ylitalo Ritva; Rontu Riikka; Nikkilä Matti; Wuolijoki Erkki; Ylitalo Pauli
Microcrystalline chitosan is ineffective to decrease plasma lipids in both apolipoprotein E epsilon 4 carriers and non-carriers: a long-term placebo-controlled trial in hypercholesterolaemic volunteers.
Basic & clinical pharmacology & toxicology 2005;97(2):98-103.
2005: Kampman Olli; Anttila Sami; Illi Ari; Mattila Kari M; Rontu Riikka; Leinonen Esa; Lehtimäki Terho
Interaction of tumor necrosis alpha - G308A and epidermal growth factor gene polymorphisms in early-onset schizophrenia.
European archives of psychiatry and clinical neuroscience 2005;255(4):279-83.
2005: Päivä Hannu; Thelen Karin M; Van Coster Rudy; Smet Joél; De Paepe Boel; Mattila Kari M; Laakso Juha; Lehtimäki Terho; von Bergmann Klaus; Lütjohann Dieter; Laaksonen Reijo
High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial.
Clinical pharmacology and therapeutics 2005;78(1):60-8.
2005: Anttila S; Illi A; Kampman O; Mattila K M; Lehtimäki T; Leinonen E
Lack of association between two polymorphisms of brain-derived neurotrophic factor and response to typical neuroleptics.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(7):885-90.
2005: Puttonen Sampsa; Keltikangas-Järvinen Liisa; Elovainio Marko; Kivimäki Mika; Rontu Riikka; Lehtimäki Terho
Epidermal growth factor A61G polymorphism and cardiac autonomic control in adults.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(5):702-7.
2005: Hurme Mikko; Paavilainen Paula M; Pertovaara Marja; Jylhä Marja; Karhunen Pekka J; Hervonen Antti; Lehtimäki Terho
IgA levels are predictors of mortality in Finnish nonagenarians.
Mechanisms of ageing and development 2005;126(6-7):829-31.
2005: Fan Yue-Mei; Dastidar Prasun; Jokela Hannu; Punnonen Reijo; Lehtimäki Terho
Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2005;90(6):3786-92.
2005: Siirtola Arja; Antikainen Marjatta; Ala-Houhala Marja; Koivisto Anna-Maija; Solakivi Tiina; Virtanen Suvi M; Jokela Hannu; Lehtimäki Terho; Holmberg Christer; Salo Matti K
Insulin resistance, LDL particle size, and LDL susceptibility to oxidation in pediatric kidney and liver recipients.
Kidney international 2005;67(5):2046-55.
2005: Islam Md Shaheenul; Raitakari Olli T; Juonala Markus; Kähönen Mika; Hutri-Kähönen Nina; Collings Auni; Aalto-Setälä Katriina; Kontula Kimmo; Marniemi Jukka; Viikari Jorma S A; Lehtimäki Terho
Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 2005;180(1):79-86.
2005: Pöllänen Perttu J; Lehtimäki Terho; Mikkelsson Jussi; Ilveskoski Erkki; Kunnas Tarja; Perola Markus; Penttilä Antti; Mattila Kari M; Nikkari Seppo T; Syrjäkoski Kirsi; Karhunen Pekka J
Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques.
Atherosclerosis 2005;180(1):73-8.
2005: Huuhka Martti; Anttila Sami; Leinonen Esa; Huuhka Kaija; Rontu Riikka; Mattila Kari M; Huhtala Heini; Lehtimäki Terho
The apolipoprotein E polymorphism is not associated with response to electroconvulsive therapy in major depressive disorder.
The journal of ECT 2005;21(1):7-11.
2005: Viiri Leena E; Loimaala Antti; Nenonen Arja; Islam Shaheenul; Vuori Ilkka; Karhunen Pekka J; Lehtimäki Terho
The association of the apolipoprotein E gene promoter polymorphisms and haplotypes with serum lipid and lipoprotein concentrations.
Atherosclerosis 2005;179(1):161-7.
2005: Hurme M; Lehtimäki T; Jylhä M; Karhunen P J; Hervonen A
Interleukin-6 -174G/C polymorphism and longevity: a follow-up study.
Mechanisms of ageing and development 2005;126(3):417-8.
2005: Niemi Anna-Kaisa; Moilanen Jukka S; Tanaka Masashi; Hervonen Antti; Hurme Mikko; Lehtimäki Terho; Arai Yasumichi; Hirose Nobuyoshi; Majamaa Kari
A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects.
European journal of human genetics : EJHG 2005;13(2):166-70.
2005: Solakivi T; Jaakkola O; Salomäki A; Peltonen N; Metso S; Lehtimäki T; Jokela H; Nikkari S T
HDL enhances oxidation of LDL in vitro in both men and women.
Lipids in health and disease 2005;4():25.
2005: Rontu Riikka; Metso Saara; Jaakkola Olli; Nikkilä Matti; Jokela Hannu; Lehtimäki Terho
Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2005;43(4):357-60.
2005: Solakivi Tiina; Jaakkola Olli; Kalela Anne; Pispa Mari; Salomäki Anne; Lehtimäki Terho; Höyhtyä Matti; Jokela Hannu; Nikkari Seppo T
Lipoprotein docosapentaenoic acid is associated with serum matrix metalloproteinase-9 concentration.
Lipids in health and disease 2005;4():8.
2004: Kunnas Tarja A; Lehtimäki Terho; Karhunen Pekka J; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Knuuti Juhani; Nikkari Seppo T
Estrogen receptor genotype modulates myocardial perfusion in young men.
Journal of molecular medicine (Berlin, Germany) 2004;82(12):821-5.
2004: Pertovaara M; Lehtimäki T; Rontu R; Antonen J; Pasternack A; Hurme M
Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome.
Rheumatology (Oxford, England) 2004;43(12):1484-7.
2004: Hulkkonen J; Pertovaara M; Antonen J; Pasternack A; Hurme M; Pöllänen P; Lehtimäki T
Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome.
Rheumatology (Oxford, England) 2004;43(12):1476-9.
2004: Kampman Olli; Anttila Sami; Illi Ari; Saarela Marika; Rontu Riikka; Mattila Kari M; Leinonen Esa; Lehtimäki Terho
Neuregulin genotype and medication response in Finnish patients with schizophrenia.
Neuroreport 2004;15(16):2517-20.
2004: Aittoniemi Janne; Fan Yue-Mei; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Knuuti Juhani; Hulkkonen Janne; Hurme Mikko; Lehtimäki Terho
The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men.
International journal of cardiology 2004;97(2):317-8.
2004: Airla Nina; Luomala Mari; Elovaara Irina; Kettunen Eeva; Knuutila Sakari; Lehtimäki Terho
Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results.
Journal of neurology 2004;251(10):1215-9.
2004: Koivu T A; Uibu T; Roto P; Fan Y M; Lehtinen S; Jokela H; Ehnholm C; Nikkari S T; Lehtimäki T
Apolipoprotein E and A-IV polymorphisms in ethnic Russians living in Estonia.
Genetika 2004;40(9):1293-5.
2004: Saarela Marika S; Lehtimäki Terho; Rinne Juha O; Hervonen Antti; Jylhä Marja; Röyttä Matias; Ahonen Jukka-Pekka; Mattila Kari M
Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns.
Neuroscience letters 2004;367(3):336-9.
2004: Rontu Riikka; Lehtimäki Terho; Ilveskoski Erkki; Mikkelsson Jussi; Kajander Olli; Goebeler Sirkka; Perola Markus; Penttilä Antti; Karhunen Pekka J
Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study.
Pharmacogenetics 2004;14(8):479-85.
2004: Päivä Hannu; Lehtimäki Terho; Laakso Juha; Ruokonen Inkeri; Tervonen Riitta; Metso Saara; Nikkilä Matti; Wuolijoki Erkki; Laaksonen Reijo
Dietary composition as a determinant of plasma asymmetric dimethylarginine in subjects with mild hypercholesterolemia.
Metabolism: clinical and experimental 2004;53(8):1072-5.
2004: Leskinen Yrjö; Lehtimäki Terho; Loimaala Antti; Huhtala Heini; Salenius Juha P; Oja Simo S; Saha Heikki
Homocysteine and carotid atherosclerosis in chronic renal failure--the confounding effect of renal function.
Atherosclerosis 2004;175(2):315-23.
2004: Järvisalo Mikko J; Lehtimäki Terho; Raitakari Olli T
Determinants of arterial nitrate-mediated dilatation in children: role of oxidized low-density lipoprotein, endothelial function, and carotid intima-media thickness.
Circulation 2004;109(23):2885-9.
2004: Anttila Sami; Illi Ari; Kampman Olli; Mattila Kari M; Lehtimäki Terho; Leinonen Esa
Association of EGF polymorphism with schizophrenia in Finnish men.
Neuroreport 2004;15(7):1215-8.
2004: Anttila Sami; Illi Ari; Kampman Olli; Mattila Kari M; Lehtimäki Terho; Leinonen Esa
Interaction between NOTCH4 and catechol-O-methyltransferase genotypes in schizophrenia patients with poor response to typical neuroleptics.
Pharmacogenetics 2004;14(5):303-7.
2004: Pulkkinen K; Luomala M; Kuusisto H; Lehtimäki T; Saarela M; Jalonen T O; Elovaara I
Increase in CCR5 Delta32/Delta32 genotype in multiple sclerosis.
Acta neurologica Scandinavica 2004;109(5):342-7.
2004: Metso S; Loimaala A; Mercuri M F; Nenonen A; Vuori I; Oja P; Bond M G; Laine S; Rontu R; Lehtimäki Terho
Circulating oxidized low-density lipoprotein and common carotid artery intima-media thickness in a random sample of middle-aged men.
Journal of biomedical science 2004;11(3):356-61.
2004: Siirtola Arja; Antikainen Marjatta; Ala-Houhala Marja; Solakivi Tiina; Jokela Hannu; Lehtimäki Terho; Holmberg Christer; Salo Matti K
Studies of LDL particle size and susceptibility to oxidation and association with glucose metabolism in children after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2004;23(4):418-26.
2004: Järvisalo Mikko J; Raitakari Maria; Toikka Jyri O; Putto-Laurila Anne; Rontu Riikka; Laine Seppo; Lehtimäki Terho; Rönnemaa Tapani; Viikari Jorma; Raitakari Olli T
Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes.
Circulation 2004;109(14):1750-5.
2004: Ainiala Hanna; Hietaharju Aki; Dastidar Prasun; Loukkola Jukka; Lehtimäki Terho; Peltola Jukka; Korpela Markku; Heinonen Tomi; Nikkari Seppo T
Increased serum matrix metalloproteinase 9 levels in systemic lupus erythematosus patients with neuropsychiatric manifestations and brain magnetic resonance imaging abnormalities.
Arthritis and rheumatism 2004;50(3):858-65.
2004: Siirtola Arja; Antikainen Marjatta; Ala-Houhala Marja; Koivisto Anna-Maija; Solakivi Tiina; Jokela Hannu; Lehtimäki Terho; Holmberg Christer; Salo Matti K
Serum lipids in children 3 to 5 years after kidney, liver, and heart transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2004;17(3):109-19.
2004: Rontu Riikka; Solakivi Tiina; Teisala Klaus; Lehtimäki Terho; Punnonen Reijo; Jokela Hannu
Impact of long-term hormone replacement therapy on in vivo and in vitro markers of lipid oxidation.
Free radical research 2004;38(2):129-37.
2004: Jokela Hannu; Salomäki Anne; Lehtimäki Terho; Teisala Klaus; Heinonen Pentti K; Aine Risto; Rontu Riikka; Punnonen Reijo
Fatty acid and cholesterol composition of the uterine artery intima in relation to menopausal status, age, and serum cholesterol.
Maturitas 2004;47(2):115-22.
2004: Mäkelä Riikka; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Jaakkola Olli; Knuuti Juhani; Lehtimäki Terho
Myeloperoxidase gene variation and coronary flow reserve in young healthy men.
Journal of biomedical science 2004;11(1):59-64.
2004: Raitakari Maria; Ilvonen Thomas; Ahotupa Markku; Lehtimäki Terho; Harmoinen Aimo; Suominen Pauli; Elo Juhani; Hartiala Jaakko; Raitakari Olli T
Weight reduction with very-low-caloric diet and endothelial function in overweight adults: role of plasma glucose.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(1):124-8.
2004: Limnell Vilho; Pasternack Rafael; Karjalainen Jussi; Virtanen Vesa; Lehtimäki Terho; Aittoniemi Janne
Seropositivity for Helicobacter pylori antibodies is associated with lower occurrence of venous bypass graft occlusion.
Scandinavian journal of infectious diseases 2004;36(8):601-3.
2004: Kampman Olli; Anttila Sami; Illi Ari; Mattila Kari M; Rontu Riikka; Leinonen Esa; Lehtimäki Terho
Apolipoprotein E polymorphism is associated with age of onset in schizophrenia.
Journal of human genetics 2004;49(7):355-9.
2003: Valkonen Veli-Pekka; Laakso Juha; Päivä Hannu; Lehtimäki Terho; Lakka Timo A; Isomustajärvi Marja; Ruokonen Inkeri; Salonen Jukka T; Laaksonen Reijo
Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels?
Atherosclerosis. Supplements 2003;4(4):19-22.
2003: Leskinen Yrjö; Lehtimäki Terho; Loimaala Antti; Lautamatti Visa; Kallio Timo; Huhtala Heini; Salenius Juha P; Saha Heikki
Carotid atherosclerosis in chronic renal failure-the central role of increased plaque burden.
Atherosclerosis 2003;171(2):295-302.
2003: Luomala M; Lehtimäki T; Huhtala H; Ukkonen M; Koivula T; Hurme M; Elovaara I
Promoter polymorphism of IL-10 and severity of multiple sclerosis.
Acta neurologica Scandinavica 2003;108(6):396-400.
2003: Metso Saara; Ylitalo Ritva; Nikkilä Matti; Wuolijoki Erkki; Ylitalo Pauli; Lehtimäki Terho
The effect of long-term microcrystalline chitosan therapy on plasma lipids and glucose concentrations in subjects with increased plasma total cholesterol: a randomised placebo-controlled double-blind crossover trial in healthy men and women.
European journal of clinical pharmacology 2003;59(10):741-6.
2003: Rontu Riikka; Karhunen Pekka J; Ilveskoski Erkki; Mikkelsson Jussi; Kajander Olli; Perola Markus; Penttilä Antti; Koivisto Anna-Maija; Lehtimäki Terho
Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study.
Atherosclerosis 2003;171(1):31-7.
2003: Kampman Olli; Anttila Sami; Illi Ari; Lehtimäki Terho; Mattila Kari M; Roivas Markus; Leinonen Esa
Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophrenia.
Psychiatry research 2003;121(1):89-92.
2003: Jolma Pasi; Kööbi Peeter; Kalliovalkama Jarkko; Kähönen Mika; Fan Meng; Saha Heikki; Helin Heikki; Lehtimäki Terho; Pörsti Ilkka
Increased calcium intake reduces plasma cholesterol and improves vasorelaxation in experimental renal failure.
American journal of physiology. Heart and circulatory physiology 2003;285(5):H1882-9.
2003: Illi Ari; Mattila Kari M; Kampman Olli; Anttila Sami; Roivas Markus; Lehtimäki Terho; Leinonen Esa
Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophrenia.
Journal of clinical psychopharmacology 2003;23(5):429-34.
2003: Lehtimäki Terho; Laaksonen Reijo; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Mattila Kari; Ilveskoski Erkki; Luomala Mari; Saikku Pekka; Knuuti Juhani; Hurme Mikko
Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.
Pharmacogenetics 2003;13(10):633-9.
2003: Jokela Hannu; Dastidar Prasun; Rontu Riikka; Salomäki Anne; Teisala Klaus; Lehtimäki Terho; Punnonen Reijo
Effects of long-term estrogen replacement therapy versus combined hormone replacement therapy on nitric oxide-dependent vasomotor function.
The Journal of clinical endocrinology and metabolism 2003;88(9):4348-54.
2003: Mäkelä Riikka; Dastidar Prasun; Jokela Hannu; Saarela Marika; Punnonen Reijo; Lehtimäki Terho
Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to myeloperoxidase promoter polymorphism.
The Journal of clinical endocrinology and metabolism 2003;88(8):3823-8.
2003: Leskinen Yrjö; Groundstroem Kaj; Virtanen Vesa; Lehtimäki Terho; Huhtala Heini; Saha Heikki
Risk factors for aortic atherosclerosis determined by transesophageal echocardiography in patients with CRF.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2003;42(2):277-85.
2003: Eklund Carita; Jahan Farhana; Pessi Tanja; Lehtimäki Terho; Hurme Mikko
Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals.
European cytokine network 2003;14(3):168-71.
2003: Mäkelä Riikka; Karhunen Pekka J; Kunnas Tarja A; Ilveskoski Erkki; Kajander Olli A; Mikkelsson Jussi; Perola Markus; Penttilä Antti; Lehtimäki Terho
Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.
Laboratory investigation; a journal of technical methods and pathology 2003;83(7):919-25.
2003: Harmoinen Aimo; Lehtimäki Terho; Korpela Markku; Turjanmaa Väinö; Saha Heikki
Diagnostic accuracies of plasma creatinine, cystatin C, and glomerular filtration rate calculated by the Cockcroft-Gault and Levey (MDRD) formulas.
Clinical chemistry 2003;49(7):1223-5.
2003: Marchesani Marja; Hakkarainen Anna; Tuomainen Tomi-Pekka; Kaikkonen Jari; Pukkala Eero; Uimari Pekka; Seppälä Eija; Matikainen Mika; Kallioniemi Olli-P; Schleutker Johanna; Lehtimäki Terho; Salonen Jukka T
New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.
Journal of the National Cancer Institute 2003;95(11):812-8.
2003: Anttila Sami; Kampman Olli; Illi Ari; Roivas Markus; Mattila Kari M; Lassila Vesa; Lehtimäki Terho; Leinonen Esa
NOTCH4 gene promoter polymorphism is associated with the age of onset in schizophrenia.
Psychiatric genetics 2003;13(2):61-4.
2003: Illi Ari; Kampman Olli; Anttila Sami; Roivas Markus; Mattila Kari M; Lehtimäki Terho; Leinonen Esa
Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neuroleptics.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(3):147-51.
2003: Metso Saara; Nikkilä Matti; Laippala Pekka; Jaakkola Olli; Solakivi Tiina; Lehtimäki Terho
Oxidized LDL autoantibodies are related to apolipoprotein E phenotype, independently of postprandial change in plasma triglycerides and LDL size, among patients with angiographically verified coronary artery disease and healthy controls.
Journal of biomedical science 2003;10(3):345-51.
2003: Päivä Hannu; Lehtimäki Terho; Laakso Juha; Ruokonen Inkeri; Rantalaiho Vappu; Wirta Ole; Pasternack Amos; Laaksonen Reijo
Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy.
Metabolism: clinical and experimental 2003;52(3):303-7.
2003: Lehtinen Saara; Rantalaiho Vappu; Wirta Ole; Pasternack Amos; Laippala Pekka; Koivula Timo; Lehtimäki Terho
Apolipoprotein E gene polymorphism, hypercholesterolemia and glomerular filtration rate in type 2 diabetic subjects: a 9-year follow-up study.
Journal of biomedical science 2003;10(2):260-5.
2003: Päivä Hannu; Laakso Juha; Lehtimäki Terho; Isomustajärvi Marja; Ruokonen Inkeri; Laaksonen Reijo
Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors.
Journal of cardiovascular pharmacology 2003;41(2):219-22.
2003: Koivu Tommi A; Fan Yue-Mei; Mattila Kari M; Dastidar Prasun; Jokela Hannu; Nikkari Seppo T; Kunnas Tarja; Punnonen Reijo; Lehtimäki Terho
The effect of hormone replacement therapy on atherosclerotic severity in relation to ESR1 genotype in postmenopausal women.
Maturitas 2003;44(1):29-38.
2003: Mattila Kari M; Hiltunen Mikko; Rinne Juha O; Mannermaa Arto; Röyttä Matias; Alafuzoff Irina; Laippala Pekka; Soininen Hilkka; Lehtimäki Terho
Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients.
Neuroscience letters 2003;337(1):61-3.
2003: Janatuinen Tuula; Laakso Juha; Laaksonen Reijo; Vesalainen Risto; Nuutila Pirjo; Lehtimäki Terho; Raitakari Olli T; Knuuti Juhani
Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults.
Vascular medicine (London, England) 2003;8(3):185-9.
2003: Puttonen Sampsa; Elovainio Marko; Kivimäki Mika; Lehtimäki Terho; Keltikangas-Järvinen Liisa
The combined effects of apolipoprotein E polymorphism and low-density lipoprotein cholesterol on cognitive performance in young adults.
Neuropsychobiology 2003;48(1):35-40.
2002: Hämelahti P; Järvinen O; Sisto T; Wirta V; Ilveskoski E; Koivula T; Lehtimäki T
Methylenetetrahydrofolate reductase gene C677T mutation is related to the defects in the internal elastic lamina of the artery wall.
European journal of clinical investigation 2002;32(12):869-73.
2002: Kunnas Tarja A; Lehtimäki Terho; Laaksonen Reijo; Ilveskoski Erkki; Janatuinen Tuula; Vesalainen Risto; Nuutila Pirjo; Karhunen Pekka J; Knuuti Juhani; Nikkari Seppo T
Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study.
Journal of molecular medicine (Berlin, Germany) 2002;80(12):802-7.
2002: Laaksonen R; Janatuinen T; Vesalainen R; Lehtimäki T; Elovaara I; Jaakkola O; Jokela H; Laakso J; Nuutila P; Punnonen K; Raitakari O; Saikku P; Salminen K; Knuuti J
High oxidized LDL and elevated plasma homocysteine contribute to the early reduction of myocardial flow reserve in healthy adults.
European journal of clinical investigation 2002;32(11):795-802.
2002: Pöllänen Perttu J; Lehtimäki Terho; Ilveskoski Erkki; Mikkelsson Jussi; Kajander Olli A; Laippala Pekka; Perola Markus; Goebeler Sirkka; Penttilä Antti; Mattila Kari M; Syrjäkoski Kirsi; Koivula Timo; Nikkari Seppo T; Karhunen Pekka J
Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: the Helsinki Sudden Death Study.
Atherosclerosis 2002;164(2):329-35.
2002: Wirta V; Saransaari P; Wirta O; Rantalaiho V; Oja S S; Pasternack A; Koivula T; Lehtimäki T
Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia and occlusive retinal vascular disease in type 2 diabetic and non-diabetic subjects.
Clinical nephrology 2002;58(3):171-8.
2002: Lehtimäki Terho; Dastidar Prasun; Jokela Hannu; Koivula Timo; Lehtinen Saara; Ehnholm Christian; Punnonen Reijo
Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype.
The Journal of clinical endocrinology and metabolism 2002;87(9):4147-53.
2002: Leskinen Yrjö; Salenius Juha P; Lehtimäki Terho; Huhtala Heini; Saha Heikki
The prevalence of peripheral arterial disease and medial arterial calcification in patients with chronic renal failure: requirements for diagnostics.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;40(3):472-9.
2002: Mattila K M; Rinne J O; Röyttä M; Laippala P; Lehtimäki T
Lack of association between an estrogen receptor 1 gene polymorphism and Parkinson's disease with dementia.
Acta neurologica Scandinavica 2002;106(3):128-30.
2002: Järvisalo Mikko J; Harmoinen Aimo; Hakanen Maarit; Paakkunainen Ulla; Viikari Jorma; Hartiala Jaakko; Lehtimäki Terho; Simell Olli; Raitakari Olli T
Elevated serum C-reactive protein levels and early arterial changes in healthy children.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(8):1323-8.
2002: Lehtimäki T; Laaksonen R; Mattila K M; Janatuinen T; Vesalainen R; Nuutila P; Laakso J; Jaakkola O; Koivula T; Knuuti J
Oestrogen receptor gene variation is a determinant of coronary reactivity in healthy young men.
European journal of clinical investigation 2002;32(6):400-4.
2002: Lehtimäki Terho; Kunnas Tarja A; Mattila Kari M; Perola Markus; Penttilä Antti; Koivula Timo; Karhunen Pekka J
Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study.
Journal of molecular medicine (Berlin, Germany) 2002;80(3):176-80.
2002: Syrjänen Jaana; Hurme Mikko; Lehtimäki Terho; Mustonen Jukka; Pasternack Amos
Polymorphism of the cytokine genes and IgA nephropathy.
Kidney international 2002;61(3):1079-85.
2002: Järvisalo Mikko J; Putto-Laurila Anne; Jartti Laura; Lehtimäki Terho; Solakivi Tiina; Rönnemaa Tapani; Raitakari Olli T
Carotid artery intima-media thickness in children with type 1 diabetes.
Diabetes 2002;51(2):493-8.
2002: Kalela A; Koivu T A; Höyhtyä M; Jaakkola O; Lehtimäki T; Sillanaukee P; Nikkari S T
Association of serum MMP-9 with autoantibodies against oxidized LDL.
Atherosclerosis 2002;160(1):161-5.
2002: Limnell Vilho; Aittoniemi Janne; Vaarala Outi; Lehtimäki Terho; Laine Seppo; Virtanen Vesa; Palosuo Timo; Miettinen Ari
Association of mannan-binding lectin deficiency with venous bypass graft occlusions in patients with coronary heart disease.
Cardiology 2002;98(3):123-6.
2002: Kalela A; Koivu T A; Sisto T; Kanervisto J; Höyhtyä M; Sillanaukee P; Lehtimäki T; Nikkari S T
Serum matrix metalloproteinase-9 concentration in angiographically assessed coronary artery disease.
Scandinavian journal of clinical and laboratory investigation 2002;62(5):337-42.
2002: Ylitalo Ritva; Lehtinen Saara; Wuolijoki Erkki; Ylitalo Pauli; Lehtimäki Terho
Cholesterol-lowering properties and safety of chitosan.
Arzneimittel-Forschung 2002;52(1):1-7.
2001: Valkonen V P; Päivä H; Salonen J T; Lakka T A; Lehtimäki T; Laakso J; Laaksonen R
Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine.
Lancet 2001;358(9299):2127-8.
2001: Ilveskoski E; Kajander O A; Lehtimäki T; Kunnas T; Karhunen P J; Heinälä P; Virkkunen M; Alho H
Association of neuropeptide y polymorphism with the occurrence of type 1 and type 2 alcoholism.
Alcoholism, clinical and experimental research 2001;25(10):1420-2.
2001: Fan Y M; Laaksonen R; Janatuinen T; Vesalainen R; Nuutila P; Knuuti J; Lehtimäki T
Effects of pravastatin therapy on serum lipids and coronary reactivity are not associated with SREBP cleavage-activating protein polymorphism in healthy young men.
Clinical genetics 2001;60(4):319-21.
2001: Malin R; Laaksonen R; Knuuti J; Janatuinen T; Vesalainen R; Nuutila P; Lehtimäki T
Paraoxonase genotype modifies the effect of pravastatin on high-density lipoprotein cholesterol.
Pharmacogenetics 2001;11(7):625-33.
2001: Janatuinen T; Laaksonen R; Vesalainen R; Raitakari O; Lehtimäki T; Nuutila P; Knuuti J
Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults.
Journal of cardiovascular pharmacology 2001;38(4):561-8.
2001: Pöllänen P J; Karhunen P J; Mikkelsson J; Laippala P; Perola M; Penttilä A; Mattila K M; Koivula T; Lehtimäki T
Coronary artery complicated lesion area is related to functional polymorphism of matrix metalloproteinase 9 gene: an autopsy study.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(9):1446-50.
2001: Malin R; Loimaala A; Nenonen A; Mercuri M; Vuori I; Pasanen M; Oja P; Bond G; Koivula T; Lehtimäki T
Relationship between high-density lipoprotein paraoxonase gene M/L55 polymorphism and carotid atherosclerosis differs in smoking and nonsmoking men.
Metabolism: clinical and experimental 2001;50(9):1095-101.
2001: Malin R; Knuuti J; Janatuinen T; Laaksonen R; Vesalainen R; Nuutila P; Jokela H; Laakso J; Jaakkola O; Solakivi T; Lehtimäki T
Paraoxonase gene polymorphisms and coronary reactivity in young healthy men.
Journal of molecular medicine (Berlin, Germany) 2001;79(8):449-58.
2001: Koivu T A; Dastidar P; Jokela H; Nikkari S T; Jaakkola O; Koivula T; Punnonen R; Lehtimäki T
The relation of oxidized LDL autoantibodies and long-term hormone replacement therapy to ultrasonographically assessed atherosclerotic plaque quantity and severity in postmenopausal women.
Atherosclerosis 2001;157(2):471-9.
2001: Malin R; Järvinen O; Sisto T; Koivula T; Lehtimäki T
Paraoxonase producing PON1 gene M/L55 polymorphism is related to autopsy-verified artery-wall atherosclerosis.
Atherosclerosis 2001;157(2):301-7.
2001: Kalela A; Laaksonen R; Lehtimäki T; Koivu T A; Höyhtyä M; Janatuinen T; Pöllänen P; Vesalainen R; Saikku P; Knuuti J; Nikkari S T
Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases.
The American journal of cardiology 2001;88(2):173-5, A6.
2001: Siirtola A; Solakivi T; Jokela H; Ala-Houhala M; Antikainen M; Holmberg C; Lehtimäki T; Salo M K
Hypertriglyceridemia and low serum HDL cholesterol are common in children after liver transplantation.
Transplantation proceedings 2001;33(4):2449.
2001: Malin R; Laine S; Rantalaiho V; Wirta O; Pasternack A; Jokela H; Alho H; Koivula T; Lehtimäki T
Lipid peroxidation is increased in paraoxonase L55 homozygotes compared with M-allele carriers.
Free radical research 2001;34(5):477-84.
2001: Mattila K M; Luomala M; Lehtimäki T; Laippala P; Koivula T; Elovaara I
Interaction between ESR1 and HLA-DR2 may contribute to the development of MS in women.
Neurology 2001;56(9):1246-7.
2001: Seppänen-Laakso T; Laakso I; Vanhanen H; Kiviranta K; Lehtimäki T; Hiltunen R
Major human plasma lipid classes determined by quantitative high-performance liquid chromatography, their variation and associations with phospholipid fatty acids.
Journal of chromatography. B, Biomedical sciences and applications 2001;754(2):437-45.
2001: Luomala M; Lehtimäki T; Elovaara I; Wang X; Ukkonen M; Mattila K; Laippala P; Koivula T; Hurme M
A study of interleukin-1 cluster genes in susceptibility to and severity of multiple sclerosis.
Journal of the neurological sciences 2001;185(2):123-7.
2001: Luomala M; Elovaara I; Ukkonen M; Koivula T; Lehtimäki T
The combination of HLA-DR1 and HLA-DR53 protects against MS.
Neurology 2001;56(3):383-5.
2001: Malin R; Lehtinen S; Luoma P; Näyhä S; Hassi J; Koivula T; Lehtimäki T
Serum lipid levels and M/L55 allele distribution of HDL paraoxonase gene in Saami and Finnish men.
International journal of circumpolar health 2001;60(1):16-24.
2000: Ilveskoski E; Järvinen O; Sisto T; Karhunen P J; Laippala P; Lehtimäki T
Apolipoprotein E polymorphism and atherosclerosis: association of the epsilon4 allele with defects in the internal elastic lamina.
Atherosclerosis 2000;153(1):155-60.
2000: Ilveskoski E; Loimaala A; Mercuri M F; Lehtimäki T; Pasanen M; Nenonen A; Oja P; Bond M G; Koivula T; Karhunen P J; Vuori I
Apolipoprotein E polymorphism and carotid artery intima-media thickness in a random sample of middle-aged men.
Atherosclerosis 2000;153(1):147-53.
2000: Syrjänen J; Huang X H; Mustonen J; Koivula T; Lehtimäki T; Pasternack A
Angiotensin-converting enzyme insertion/deletion polymorphism and prognosis of IgA nephropathy.
Nephron 2000;86(2):115-21.
2000: Kunnas T A; Laippala P; Penttilä A; Lehtimäki T; Karhunen P J
Association of polymorphism of human alpha oestrogen receptor gene with coronary artery disease in men: a necropsy study.
BMJ (Clinical research ed.) 2000;321(7256):273-4.
2000: Saarelainen S; Lehtimäki T; Nikkilä M; Solakivi T; Nieminen M M; Jaakkola O
Association between apolipoprotein E alleles and autoantibodies against oxidised low-density lipoprotein.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(5):477-8.
2000: Luomala M; Elovaara I; Ukkonen M; Koivula T; Lehtimäki T
Plasminogen activator inhibitor 1 gene and risk of MS in women.
Neurology 2000;54(9):1862-4.
2000: Elovaara I; Ukkonen M; Leppäkynnäs M; Lehtimäki T; Luomala M; Peltola J; Dastidar P
Adhesion molecules in multiple sclerosis: relation to subtypes of disease and methylprednisolone therapy.
Archives of neurology 2000;57(4):546-51.
1999: Huang X H; Loimaala A; Nenonen A; Mercuri M; Vuori I; Pasanen M; Oja P; Bond G; Koivula T; Hiltunen T P; Nikkari T; Lehtimäki T
Relationship of angiotensin-converting enzyme gene polymorphism to carotid wall thickness in middle-aged men.
Journal of molecular medicine (Berlin, Germany) 1999;77(12):853-8.
1999: Harmoinen A P; Kouri T T; Wirta O R; Lehtimäki T J; Rantalaiho V; Turjanmaa V M; Pasternack A I
Evaluation of plasma cystatin C as a marker for glomerular filtration rate in patients with type 2 diabetes.
Clinical nephrology 1999;52(6):363-70.
1999: Salonen J T; Malin R; Tuomainen T P; Nyyssönen K; Lakka T A; Lehtimäki T
Polymorphism in high density lipoprotein paraoxonase gene and risk of acute myocardial infarction in men: prospective nested case-control study.
BMJ (Clinical research ed.) 1999;319(7208):487-9; discussion 490.
1999: Ilveskoski E; Perola M; Lehtimäki T; Laippala P; Savolainen V; Pajarinen J; Penttilä A; Lalu K H; Männikkö A; Liesto K K; Koivula T; Karhunen P J
Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: an autopsy study.
Circulation 1999;100(6):608-13.
1999: Malin R; Rantalaiho V; Huang X H; Wirta O; Pasternack A; Leinonen J S; Alho H; Jokela H; Koivula T; Tanaka T; Okada K; Ochi H; Toyokuni S; Lehtimäki T
Association between M/L55-polymorphism of paraoxonase enzyme and oxidative DNA damage in patients with type 2 diabetes mellitus and in control subjects.
Human genetics 1999;105(1-2):179-80.
1999: Wegiel J; Wísniewski H M; Morys J; Tarnawski M; Kuchna I; Dziewiatkowski J; Pirttilä T; Krivimäki T; Lehtimäki T; Lach B
Neuronal loss and beta-amyloid removal in the amygdala of people with Down syndrome.
Neurobiology of aging 1999;20(3):259-69.
1999: Dastidar P; Heinonen T; Lehtimäki T; Ukkonen M; Peltola J; Erilä T; Laasonen E; Elovaara I
Volumes of brain atrophy and plaques correlated with neurological disability in secondary progressive multiple sclerosis.
Journal of the neurological sciences 1999;165(1):36-42.
1999: Saarelainen S; Lehtimäki T; Jaak-kola O; Poussa T; Nikkilä M; Solakivi T; Nieminen M M
Autoantibodies against oxidised low-density lipoprotein in patients with obstructive sleep apnoea.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1999;37(5):517-20.
1999: Donohoe G G; Salomäki A; Lehtimäki T; Pulkki K; Kairisto V
Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis.
Clinical chemistry 1999;45(1):143-6.
1999: Lehtimäki T; Lehtinen S; Solakivi T; Nikkilä M; Jaakkola O; Jokela H; Ylä-Herttuala S; Luoma J S; Koivula T; Nikkari T
Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(1):23-7.
1999: Nikkilä M; Pitkäjärvi T; Laippala P; Koivula T; Solakivi T; Lehtimäki T; Jokela H; Lehtomäki E; Seppä K; Sillanaukee P
[Men have smaller and more atherogenic LDL particles than women]
Duodecim; lääketieteellinen aikakauskirja 1999;115(5):509-14.
1998: Elovaara I; Lällä M; Spåre E; Lehtimäki T; Dastidar P
Methylprednisolone reduces adhesion molecules in blood and cerebrospinal fluid in patients with MS.
Neurology 1998;51(6):1703-8.
1998: Leinonen J; Rantalaiho V; Lehtimäki T; Koivula T; Wirta O; Pasternack A; Alho H
The association between the total antioxidant potential of plasma and the presence of coronary heart disease and renal dysfunction in patients with NIDDM.
Free radical research 1998;29(4):273-81.
1998: Mattila P M; Koskela T; Röyttä M; Lehtimäki T; Pirttilä T A; Ilveskoski E; Karhunen P; Rinne J O
Apolipoprotein E epsilon4 allele frequency is increased in Parkinson's disease only with co-existing Alzheimer pathology.
Acta neuropathologica 1998;96(4):417-20.
1998: Huang X H; Rantalaiho V; Wirta O; Pasternack A; Koivula T; Hiltunen T P; Nikkari T; Lehtimäki T
Angiotensin-converting enzyme gene polymorphism is associated with coronary heart disease in non-insulin-dependent diabetic patients evaluated for 9 years.
Metabolism: clinical and experimental 1998;47(10):1258-62.
1998: Malin R; Huang X H; Wirta O; Rantalaiho V; Pasternack A; Jokela H; Koivula T; Lehtimäki T
The Met54Leu polymorphism of paraoxonase (PON) enzyme gene is not a genetic risk factor for non-insulin-dependent diabetes mellitus in Finns.
Clinical genetics 1998;54(3):254-5.
1998: Huang X H; Rantalaiho V; Wirta O; Pasternack A; Hiltunen T P; Koivula T; Malminiemi K; Nikkari T; Lehtimäki T
Angiotensin-converting enzyme insertion/deletion polymorphism and diabetic albuminuria in patients with NIDDM followed Up for 9 years.
Nephron 1998;80(1):17-24.
1998: Wirta V; Huang X H; Wirta O; Rantalaiho V; Pasternack A; Jokela H; Koivula T; Lehtimäki T
Mutation C677T of methylenetetrahydrofolate reductase gene is not associated with coronary artery disease, but possibly with albuminuria, in type 2 diabetic patients.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1998;36(8):625-8.
1998: Leinonen J S; Alho H; Harmoinen A; Lehtimäki T; Knip M
Unaltered antioxidant activity of plasma in subjects at increased risk for IDDM.
Free radical research 1998;29(2):159-64.
1998: Leinonen J S; Rantalaiho V; Laippala P; Wirta O; Pasternack A; Alho H; Jaakkola O; Ylä-Herttuala S; Koivula T; Lehtimäki T
The level of autoantibodies against oxidized LDL is not associated with the presence of coronary heart disease or diabetic kidney disease in patients with non-insulin-dependent diabetes mellitus.
Free radical research 1998;29(2):137-41.
1998: Lehtimäki T; Uibu T; Roto P; Koivula T; Jokela H; Ehnholm C; Peltonen N; Nikkari T
Apolipoprotein E and A-IV polymorphisms in the Estonian population.
Clinical genetics 1998;54(1):106-7.
1998: Leinonen J S; Rantalaiho V; Solakivi T; Koivula T; Wirta O; Pasternack A; Alho H; Lehtimäki T
Susceptibility of LDL to oxidation is not associated with the presence of coronary heart disease or renal dysfunction in NIDDM patients.
Clinica chimica acta; international journal of clinical chemistry 1998;275(2):163-74.
1998: Ahotupa M; Marniemi J; Lehtimäki T; Talvinen K; Raitakari O T; Vasankari T; Viikari J; Luoma J; Ylä-Herttuala S
Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation.
Clinical biochemistry 1998;31(4):257-61.
1998: Lehtinen S; Luoma P; Näyhä S; Hassi J; Ehnholm C; Nikkari T; Peltonen N; Jokela H; Koivula T; Lehtimäki T
Apolipoprotein A-IV polymorphism in Saami and Finns: frequency and effect on serum lipid levels.
Annals of medicine 1998;30(2):218-23.
1998: Huang X H; Rantalaiho V; Wirta O; Pasternack A; Koivula T; Hiltunen T; Nikkari T; Lehtimäki T
Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM.
Human genetics 1998;102(3):372-8.
1998: Saarelainen S; Lehtimäki T; Kallonen E; Laasonen K; Poussa T; Nieminen M M
No relation between apolipoprotein E alleles and obstructive sleep apnea.
Clinical genetics 1998;53(2):147-8.
1998: Pitkänen O P; Nuutila P; Raitakari O T; Rönnemaa T; Koskinen P J; Iida H; Lehtimäki T J; Laine H K; Takala T; Viikari J S; Knuuti J
Coronary flow reserve is reduced in young men with IDDM.
Diabetes 1998;47(2):248-54.
1997: Leinonen J; Lehtimäki T; Toyokuni S; Okada K; Tanaka T; Hiai H; Ochi H; Laippala P; Rantalaiho V; Wirta O; Pasternack A; Alho H
New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.
FEBS letters 1997;417(1):150-2.
1997: Huang X H; Salomäki A; Malin R; Koivula T; Jokela H; Lehtimäki T
Rapid identification of angiotensin-converting enzyme genotypes by capillary electrophoresis.
Clinical chemistry 1997;43(11):2195-6.
1997: Porkka K V; Nuotio I; Pajukanta P; Ehnholm C; Suurinkeroinen L; Syvänne M; Lehtimäki T; Lahdenkari A T; Lahdenperä S; Ylitalo K; Antikainen M; Perola M; Raitakari O T; Kovanen P; Viikari J S; Peltonen L; Taskinen M R
Phenotype expression in familial combined hyperlipidemia.
Atherosclerosis 1997;133(2):245-53.
1997: Lehtimäki T; Frankberg-Lakkala H; Solakivi T; Koivisto A M; Laippala P; Ehnholm C; Jokela H; Koivula T; Nikkari T
The effect of short-term fasting, apolipoprotein E gene polymorphism, and sex on plasma lipids.
The American journal of clinical nutrition 1997;66(3):599-605.
1997: Huang X H; Koivula T; Ilveskoski E; Karhunen P J; Rantalaiho V; Wirta O; Pasternack A; Lehtimäki T
Fast 5-hour determination of angiotensin-converting enzyme genotypes from blood by SDS-PAGE using PhastSystem.
Clinica chimica acta; international journal of clinical chemistry 1997;264(1):57-64.
1997: Porkka K V; Raitakari O T; Leino A; Laitinen S; Räsänen L; Rönnemaa T; Marniemi J; Lehtimäki T; Taimela S; Dahl M; Uhari M; Akerblom H K; Viikari J S
Trends in serum lipid levels during 1980-1992 in children and young adults. The Cardiovascular Risk in Young Finns Study.
American journal of epidemiology 1997;146(1):64-77.
1997: Raitakari O T; Pitkänen O P; Lehtimäki T; Lahdenperä S; Iida H; Ylä-Herttuala S; Luoma J; Mattila K; Nikkari T; Taskinen M R; Viikari J S; Knuuti J
In vivo low density lipoprotein oxidation relates to coronary reactivity in young men.
Journal of the American College of Cardiology 1997;30(1):97-102.
1996: Taimela S; Lehtimäki T; Porkka K V; Räsänen L; Viikari J S
The effect of physical activity on serum total and low-density lipoprotein cholesterol concentrations varies with apolipoprotein E phenotype in male children and young adults: The Cardiovascular Risk in Young Finns Study.
Metabolism: clinical and experimental 1996;45(7):797-803.
1996: Nuotio I O; Porkka K V; Raitakari O T; Lehtimäki T; Marniemi J; Taimela S; Suurinkeroinen L; Viikari J S
Prevalence of hyperapobetalipoproteinemia and factors affecting the phenotype expression in children and young adults. The Cardiovascular Risk in Young Finns Study.
Atherosclerosis 1996;122(1):79-88.
1996: Nikkilä M; Pitkäjärvi T; Koivula T; Solakivi T; Lehtimäki T; Laippala P; Jokela H; Lehtomäki E; Seppä K; Sillanaukee P
Women have a larger and less atherogenic low density lipoprotein particle size than men.
Atherosclerosis 1996;119(2):181-90.
1995: Lehtimäki T; Moilanen T; Porkka K; Akerblom H K; Rönnemaa T; Räsänen L; Viikari J; Ehnholm C; Nikkari T
Association between serum lipids and apolipoprotein E phenotype is influenced by diet in a population-based sample of free-living children and young adults: the Cardiovascular Risk in Young Finns Study.
Journal of lipid research 1995;36(4):653-61.
1995: Lehtinen S; Lehtimäki T; Sisto T; Salenius J P; Nikkilä M; Jokela H; Koivula T; Ebeling F; Ehnholm C
Apolipoprotein E polymorphism, serum lipids, myocardial infarction and severity of angiographically verified coronary artery disease in men and women.
Atherosclerosis 1995;114(1):83-91.
1995: Lehtimäki T; Pirttilä T; Mehta P D; Wisniewski H M; Frey H; Nikkari T
Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease.
Human genetics 1995;95(1):39-42.
1995: Lehtimäki T; Pirttilä T; Frey H; Nikkari T
[Alzheimer's disease and the association of genetic polymorphism of apolipoprotein E and liquor beta protein in Finns]
Duodecim; lääketieteellinen aikakauskirja 1995;111(5):401-7.
1994: Lehtimäki T; Porkka K; Viikari J; Ehnholm C; Akerblom H K; Nikkari T
Apolipoprotein E phenotypes and serum lipids in newborns and 3-year-old children: the Cardiovascular Risk in Young Finns Study.
Pediatrics 1994;94(4 Pt 1):489-93.
1994: Nikkilä M; Solakivi T; Lehtimäki T; Koivula T; Laippala P; Aström B
Postprandial plasma lipoprotein changes in relation to apolipoprotein E phenotypes and low density lipoprotein size in men with and without coronary artery disease.
Atherosclerosis 1994;106(2):149-57.
1994: Porkka K V; Taimela S; Kontula K; Lehtimäki T; Aalto-Setälä K; Akerblom H K; Viikari J S
Variability gene effects of DNA polymorphisms at the apo B, apo A I/C III and apo E loci on serum lipids: the Cardiovascular Risk in Young Finns Study.
Clinical genetics 1994;45(3):113-21.
1994: Lehtimäki T; Moilanen T; Viikari J; Akerblom H; Ehnholm C; Nikkari T
[Apolipoprotein E polymorphism and serum cholesterol levels in Finnish children and adolescents]
Duodecim; lääketieteellinen aikakauskirja 1994;110(14):1313-9.
1993: Salo M K; Rantanen R; Huupponen T; Lehtimäki T; Jokela H
Apolipoprotein E phenotypes and plasma lipids in diabetic children and adolescents.
European journal of pediatrics 1993;152(7):564-8.
1993: Nikkilä M; Solakivi T; Lehtimäki T; Laippala P; Koivula T; Aström B
[Coronary artery disease and serum lipids]
Duodecim; lääketieteellinen aikakauskirja 1993;109(5):380-5.
1992: Lehtimäki T; Moilanen T; Solakivi T; Laippala P; Ehnholm C
Cholesterol-rich diet induced changes in plasma lipids in relation to apolipoprotein E phenotype in healthy students.
Annals of medicine 1992;24(1):61-6.
1991: Lehtimäki T
Determination of apolipoprotein E phenotypes from stored or postmortem serum samples.
Clinica chimica acta; international journal of clinical chemistry 1991;203(2-3):177-82.
1991: Lehtimäki T; Moilanen T; Aalto-Setälä K; Kontula K; Porkka K; Akerblom H K; Ehnholm C; Rönnemaa T; Viikari J
Association of apolipoprotein E and B polymorphisms with serum lipids.
Annals of medicine 1991;23(6):657-62.
1991: Lehtimäki T; Moilanen T; Nikkari T; Solakivi T; Porkka K; Ehnholm C; Rönnemaa T; Akerblom H K; Uhari M; Nuutinen E M
Regional differences in apolipoprotein E polymorphism in Finland.
Annals of medicine 1991;23(1):61-6.
1990: Lehtimäki T; Moilanen T; Viikari J; Akerblom H K; Ehnholm C; Rönnemaa T; Marniemi J; Dahlen G; Nikkari T
Apolipoprotein E phenotypes in Finnish youths: a cross-sectional and 6-year follow-up study.
Journal of lipid research 1990;31(3):487-95.

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