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Fred Leibach

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Jeffrey L Rausch; Maria E Johnson; Katina M Corley; Henry M Hobby; Nitin Sudhakar Shendarkar; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Depressed patients have higher body temperature: 5-HT transporter long promoter region effects.
Jeffrey L Rausch; C F Gillespie; You-Jun Fei; Henry M Hobby; T Stoming; Vadivel Ganapathy; Fred H Leibach
Antidepressant effects on kinase gene expression patterns in rat brain.
Jeffrey L Rausch; Maria E Johnson; You-Jun Fei; Jun Qing Li; Nitin Sudhakar Shendarkar; Henry M Hobby; Vadivel Ganapathy; Fred H Leibach
Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome.

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2003: Jeffrey L Rausch; Maria E Johnson; Katina M Corley; Henry M Hobby; Nitin Sudhakar Shendarkar; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Depressed patients have higher body temperature: 5-HT transporter long promoter region effects.
Neuropsychobiology 2003;47(3):120-7.
2002: Jeffrey L Rausch; C F Gillespie; You-Jun Fei; Henry M Hobby; T Stoming; Vadivel Ganapathy; Fred H Leibach
Antidepressant effects on kinase gene expression patterns in rat brain.
Neuroscience letters 2002;334(2):91-4.
2002: Jeffrey L Rausch; Maria E Johnson; You-Jun Fei; Jun Qing Li; Nitin Sudhakar Shendarkar; Henry M Hobby; Vadivel Ganapathy; Fred H Leibach
Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome.
Biological psychiatry 2002;51(9):723-32.
2001: Takeo Nakanishi; R Kekuda; You-Jun Fei; Takahiro Hatanaka; Mitsuru Sugawara; Robert G Martindale; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional characterization of a new subtype of the amino acid transport system N.
American journal of physiology. Cell physiology 2001;281(6):C1757-68.
2001: R Ling; Christy Bridges; Mitsuru Sugawara; T Fujita; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.
Biochimica et biophysica acta 2001;1512(1):15-21.
2001: Takeo Nakanishi; Takahiro Hatanaka; Wei Huang; Puttur D Prasad; Fred H Leibach; Malliga E Ganapathy; Vadivel Ganapathy
Na+- and Cl--coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes.
The Journal of physiology 2001;532(Pt 2):297-304.
2001: Takahiro Hatanaka; Takeo Nakanishi; Wei Huang; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy; Malliga E Ganapathy
Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+).
The Journal of clinical investigation 2001;107(8):1035-43.
2001: Takeo Nakanishi; Mitsuru Sugawara; Wei Huang; Robert G Martindale; Fred H Leibach; Malliga E Ganapathy; Puttur D Prasad; Vadivel Ganapathy
Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N.
Biochemical and biophysical research communications 2001;281(5):1343-8.
2000: Mitsuru Sugawara; Takeo Nakanishi; You-Jun Fei; Robert G Martindale; Malliga E Ganapathy; Fred H Leibach; Vadivel Ganapathy
Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle.
Biochimica et biophysica acta 2000;1509(1-2):7-13.
2000: Wei Huang; Heng Wang; R Kekuda; You-Jun Fei; A Friedrich; J Wang; Simon J Conway; Richard S Cameron; Fred H Leibach; Vadivel Ganapathy
Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain.
The Journal of pharmacology and experimental therapeutics 2000;295(1):392-403.
2000: X Wu; Wei Huang; Malliga E Ganapathy; Heng Wang; R Kekuda; Simon J Conway; Fred H Leibach; Vadivel Ganapathy
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
American journal of physiology. Renal physiology 2000;279(3):F449-58.
2000: You-Jun Fei; Mitsuru Sugawara; Takeo Nakanishi; Wei Huang; Heng Wang; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.
The Journal of biological chemistry 2000;275(31):23707-17.
2000: Vadivel Ganapathy; Puttur D Prasad; Malliga E Ganapathy; Fred H Leibach
Placental transporters relevant to drug distribution across the maternal-fetal interface.
The Journal of pharmacology and experimental therapeutics 2000;294(2):413-20.
2000: Takahiro Hatanaka; Wei Huang; Heng Wang; Mitsuru Sugawara; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.
Biochimica et biophysica acta 2000;1467(1):1-6.
2000: Heng Wang; Wei Huang; Mitsuru Sugawara; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.
Biochemical and biophysical research communications 2000;273(3):1175-9.
2000: You-Jun Fei; Mitsuru Sugawara; J C Liu; HW Li; Vadivel Ganapathy; Malliga E Ganapathy; Fred H Leibach
cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1.
Biochimica et biophysica acta 2000;1492(1):145-54.
2000: Mitsuru Sugawara; Takeo Nakanishi; You-Jun Fei; Wei Huang; Malliga E Ganapathy; Fred H Leibach; Vadivel Ganapathy
Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A.
The Journal of biological chemistry 2000;275(22):16473-7.
2000: X Wu; Ronald L George; Wei Huang; Heng Wang; Simon J Conway; Fred H Leibach; Vadivel Ganapathy
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
Biochimica et biophysica acta 2000;1466(1-2):315-27.
2000: M Sugawara; W Huang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy; Malliga E Ganapathy
Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2.
Journal of pharmaceutical sciences 2000;89(6):781-9.
2000: DP Rajan; Wei Huang; R Kekuda; Ronald L George; Jinzhao Wang; Simon J Conway; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Differential influence of the 4F2 heavy chain and the protein related to b(0,+) amino acid transport on substrate affinity of the heteromeric b(0,+) amino acid transporter.
The Journal of biological chemistry 2000;275(19):14331-5.
2000: Heng Wang; You-Jun Fei; R Kekuda; TL Yang-Feng; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter.
American journal of physiology. Cell physiology 2000;278(5):C1019-30.
2000: Puttur D Prasad; Sonne R Srinivas; Heng Wang; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Electrogenic nature of rat sodium-dependent multivitamin transport.
Biochemical and biophysical research communications 2000;270(3):836-40.
2000: You-Jun Fei; M F Romero; M Krause; J C Liu; Wei Huang; Vadivel Ganapathy; Fred H Leibach
A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons.
The Journal of biological chemistry 2000;275(13):9563-71.
2000: R Kekuda; Fred H Leibach; TC Furesz; C H Smith; Vadivel Ganapathy
Polarized distribution of interleukin-1 receptors and their role in regulation of serotonin transporter in placenta.
The Journal of pharmacology and experimental therapeutics 2000;292(3):1032-41.
2000: Malliga E Ganapathy; Wei Huang; DP Rajan; Alva Lee Carter; Mitsuru Sugawara; K Iseki; Fred H Leibach; Vadivel Ganapathy
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
The Journal of biological chemistry 2000;275(3):1699-707.
2000: DP Rajan; R Kekuda; Wei Huang; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine.
Biochimica et biophysica acta 2000;1463(1):6-14.
2000: A A Ogonowski; Wayne H Kaesemeyer; Liming Jin; Vadivel Ganapathy; Fred H Leibach; Robert W Caldwell
Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production.
American journal of physiology. Cell physiology 2000;278(1):C136-43.
1999: P Seth; X Wu; Wei Huang; Fred H Leibach; Vadivel Ganapathy
Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function.
The Journal of biological chemistry 1999;274(47):33388-92.
1999: Heng Wang; B Dutta; Wei Huang; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy; Puttur D Prasad
Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant.
Biochimica et biophysica acta 1999;1461(1):1-9.
1999: B Dutta; Wei Huang; Mariela M Molero; R Kekuda; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy; Puttur D Prasad
Cloning of the human thiamine transporter, a member of the folate transporter family.
The Journal of biological chemistry 1999;274(45):31925-9.
1999: Ronald L George; X Wu; Wei Huang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Molecular cloning and functional characterization of a polyspecific organic anion transporter from Caenorhabditis elegans.
The Journal of pharmacology and experimental therapeutics 1999;291(2):596-603.
1999: Wei Huang; S N Shaikh; Malliga E Ganapathy; U Hopfer; Fred H Leibach; Alva Lee Carter; Vadivel Ganapathy
Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells.
Biochemical pharmacology 1999;58(8):1361-70.
1999: DP Rajan; R Kekuda; Wei Huang; Heng Wang; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria.
The Journal of biological chemistry 1999;274(41):29005-10.
1999: DP Rajan; Wei Huang; B Dutta; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy; Puttur D Prasad
Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function.
Biochemical and biophysical research communications 1999;262(3):762-8.
1999: X Wu; Wei Huang; Puttur D Prasad; P Seth; DP Rajan; Fred H Leibach; J Chen; Simon J Conway; Vadivel Ganapathy
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1482-92.
1999: S P Kenney; R Kekuda; Puttur D Prasad; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta.
American journal of obstetrics and gynecology 1999;181(2):491-7.
1999: Puttur D Prasad; Heng Wang; Wei Huang; You-Jun Fei; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter.
Archives of biochemistry and biophysics 1999;366(1):95-106.
1999: Heng Wang; Wei Huang; You-Jun Fei; H Xia; TL Yang-Feng; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy; Puttur D Prasad
Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization.
The Journal of biological chemistry 1999;274(21):14875-83.
1999: You-Jun Fei; E Nara; J C Liu; C A Boyd; Vadivel Ganapathy; Fred H Leibach
Preferential recognition of zwitterionic dipeptides as transportable substrates by the high-affinity peptide transporter PEPT2.
Biochimica et biophysica acta 1999;1418(2):344-51.
1999: X Wu; You-Jun Fei; Wei Huang; CD Chancy; Fred H Leibach; Vadivel Ganapathy
Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter.
Biochimica et biophysica acta 1999;1418(1):239-44.
1999: Malliga E Ganapathy; Puttur D Prasad; Wei Huang; P Seth; Fred H Leibach; Vadivel Ganapathy
Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line.
The Journal of pharmacology and experimental therapeutics 1999;289(1):251-60.
1999: Puttur D Prasad; Heng Wang; Wei Huang; R Kekuda; DP Rajan; Fred H Leibach; Vadivel Ganapathy
Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function.
Biochemical and biophysical research communications 1999;255(2):283-8.
1999: R Kekuda; Heng Wang; Wei Huang; Ana M Pajor; Fred H Leibach; Lawrence D Devoe; Puttur D Prasad; Vadivel Ganapathy
Primary structure and functional characteristics of a mammalian sodium-coupled high affinity dicarboxylate transporter.
The Journal of biological chemistry 1999;274(6):3422-9.
1998: X Wu; R Kekuda; Wei Huang; You-Jun Fei; Fred H Leibach; Jeannie Chen; Simon J Conway; Vadivel Ganapathy
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
The Journal of biological chemistry 1998;273(49):32776-86.
1998: H Wang; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain.
The American journal of physiology 1998;275(4 Pt 1):C967-75.
1998: R Kekuda; Puttur D Prasad; X Wu; Heng Wang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
The Journal of biological chemistry 1998;273(26):15971-9.
1998: You-Jun Fei; T Fujita; David Lapp; Vadivel Ganapathy; Fred H Leibach
Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression.
The Biochemical journal 1998;332 ( Pt 2)():565-72.
1998: X Wu; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.
Biochemical and biophysical research communications 1998;246(3):589-95.
1998: Malliga E Ganapathy; Wei Huang; Heng Wang; Vadivel Ganapathy; Fred H Leibach
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Biochemical and biophysical research communications 1998;246(2):470-5.
1998: Y J Fei; J C Liu; T Fujita; R Liang; Vadivel Ganapathy; Fred H Leibach
Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras.
Biochemical and biophysical research communications 1998;246(1):39-44.
1998: V Torres-Zamorano; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent homo- and hetero-exchange of neutral amino acids mediated by the amino acid transporter ATB degree.
Biochemical and biophysical research communications 1998;245(3):824-9.
1998: Puttur D Prasad; Heng Wang; R Kekuda; T Fujita; You-Jun Fei; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy
Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.
The Journal of biological chemistry 1998;273(13):7501-6.
1998: P Seth; You-Jun Fei; HW Li; Wei Huang; Fred H Leibach; Vadivel Ganapathy
Cloning and functional characterization of a sigma receptor from rat brain.
Journal of neurochemistry 1998;70(3):922-31.
1998: Puttur D Prasad; Wei Huang; Heng Wang; Fred H Leibach; Vadivel Ganapathy
Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line.
Biochimica et biophysica acta 1998;1369(1):141-51.
1998: Puttur D Prasad; HW Li; You-Jun Fei; Malliga E Ganapathy; T Fujita; L H Plumley; TL Yang-Feng; Fred H Leibach; Vadivel Ganapathy
Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene.
Journal of neurochemistry 1998;70(2):443-51.
1998: Vadivel Ganapathy; Puttur D Prasad; Fred H Leibach
Use of human placenta in studies of monoamine transporters.
Methods in enzymology 1998;296():278-90.
1997: P Seth; Fred H Leibach; Vadivel Ganapathy
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor.
Biochemical and biophysical research communications 1997;241(2):535-40.
1997: DE Bockman; Vadivel Ganapathy; TG Oblak; Fred H Leibach
Localization of peptide transporter in nuclei and lysosomes of the pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1997;22(3):221-5.
1997: Puttur D Prasad; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells.
Placenta 1997;18(7):527-33.
1997: Wei Huang; Puttur D Prasad; R Kekuda; Fred H Leibach; Vadivel Ganapathy
Characterization of N5-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1997;38(8):1578-87.
1997: R Kekuda; V Torres-Zamorano; You-Jun Fei; Puttur D Prasad; HW Li; L D Mader; Fred H Leibach; Vadivel Ganapathy
Molecular and functional characterization of intestinal Na(+)-dependent neutral amino acid transporter B0.
The American journal of physiology 1997;272(6 Pt 1):G1463-72.
1997: R Kekuda; Fred H Leibach; Vadivel Ganapathy
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR.
Biochimica et biophysica acta 1997;1356(3):258-70.
1997: Puttur D Prasad; V Torres-Zamorano; R Kekuda; Fred H Leibach; Vadivel Ganapathy
Functional link between tyrosine phosphorylation and human serotonin transporter gene expression.
European journal of pharmacology 1997;325(1):85-92.
1997: R Kekuda; V Torres-Zamorano; Fred H Leibach; Vadivel Ganapathy
Human serotonin transporter: regulation by the neuroprotective agent aurintricarboxylic acid and by epidermal growth factor.
Journal of neurochemistry 1997;68(4):1443-50.
1997: Malliga E Ganapathy; Puttur D Prasad; B Mackenzie; Vadivel Ganapathy; Fred H Leibach
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.
Biochimica et biophysica acta 1997;1324(2):296-308.
1997: Matthias Brandsch; C Brandsch; Malliga E Ganapathy; Catherine Chew; Vadivel Ganapathy; Fred H Leibach
Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2).
Biochimica et biophysica acta 1997;1324(2):251-62.
1997: Y J Fei; Wen Liu; Puttur D Prasad; R Kekuda; TG Oblak; Vadivel Ganapathy; Fred H Leibach
Identification of the histidyl residue obligatory for the catalytic activity of the human H+/peptide cotransporters PEPT1 and PEPT2.
Biochemistry 1997;36(2):452-60.
1996: R Kekuda; Puttur D Prasad; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).
Biochemical and biophysical research communications 1996;229(2):553-8.
1996: Puttur D Prasad; Wei Huang; Sammanda Ramamoorthy; Alva Lee Carter; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent carnitine transport in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1996;1284(1):109-17.
1996: R Kekuda; Puttur D Prasad; You-Jun Fei; V Torres-Zamorano; S Sinha; T L Yang-Feng; Fred H Leibach; Vadivel Ganapathy
Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line.
The Journal of biological chemistry 1996;271(31):18657-61.
1996: A S Roque; Puttur D Prasad; Jatinder J Bhatia; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes.
Biochimica et biophysica acta 1996;1282(2):274-82.
1996: Puttur D Prasad; B J Hoffmans; A J Moe; C H Smith; Fred H Leibach; Vadivel Ganapathy
Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells.
Placenta 1996;17(4):201-7.
1996: U Muller; Matthias Brandsch; Puttur D Prasad; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP.
Biochemical and biophysical research communications 1996;218(2):461-5.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Human placental monoamine transporters as targets for amphetamines.
American journal of obstetrics and gynecology 1995;173(6):1782-7.
1995: Sammanda Ramamoorthy; W Liu; Y Y Ma; T L Yang-Feng; Vadivel Ganapathy; Fred H Leibach
Proton/peptide cotransporter (PEPT 2) from human kidney: functional characterization and chromosomal localization.
Biochimica et biophysica acta 1995;1240(1):1-4.
1995: Sammanda Ramamoorthy; J D Ramamoorthy; Puttur D Prasad; GK Bhat; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Regulation of the human serotonin transporter by interleukin-1 beta.
Biochemical and biophysical research communications 1995;216(2):560-7.
1995: Matthias Brandsch; C Brandsch; Puttur D Prasad; Vadivel Ganapathy; U Hopfer; Fred H Leibach
Identification of a renal cell line that constitutively expresses the kidney-specific high-affinity H+/peptide cotransporter.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(14):1489-96.
1995: Malliga E Ganapathy; Matthias Brandsch; Puttur D Prasad; Vadivel Ganapathy; Fred H Leibach
Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2.
The Journal of biological chemistry 1995;270(43):25672-7.
1995: Vadivel Ganapathy; J D Ramamoorthy; Monte A Delmonte; Fred H Leibach; Sammanda Ramamoorthy
Cyclic AMP-dependent up-regulation of the taurine transporter in a human retinal pigment epithelial cell line.
Current eye research 1995;14(9):843-50.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Andreas Papapetropoulos; John D Catravas; Fred H Leibach; Vadivel Ganapathy
Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells.
The Journal of biological chemistry 1995;270(29):17189-95.
1995: You-Jun Fei; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
The amino acid transport system y+L induced in Xenopus laevis oocytes by human choriocarcinoma cell (JAR) mRNA is functionally related to the heavy chain of the 4F2 cell surface antigen.
Biochemistry 1995;34(27):8744-51.
1995: Matthias Brandsch; Sammanda Ramamoorthy; N Marczin; John D Catravas; J W Leibach; Vadivel Ganapathy; Fred H Leibach
Regulation of taurine transport by Escherichia coli heat-stable enterotoxin and guanylin in human intestinal cell lines.
The Journal of clinical investigation 1995;96(1):361-9.
1995: W Liu; R Liang; Sammanda Ramamoorthy; You-Jun Fei; Malliga E Ganapathy; M A Hediger; Vadivel Ganapathy; Fred H Leibach
Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney.
Biochimica et biophysica acta 1995;1235(2):461-6.
1995: Lankupalle D Jayanthi; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Substrate-specific regulation of the taurine transporter in human placental choriocarcinoma cells (JAR).
Biochimica et biophysica acta 1995;1235(2):351-60.
1995: R Liang; You-Jun Fei; Puttur D Prasad; Sammanda Ramamoorthy; H Han; T L Yang-Feng; M A Hediger; Vadivel Ganapathy; Fred H Leibach
Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization.
The Journal of biological chemistry 1995;270(12):6456-63.
1995: Matthias Brandsch; Vadivel Ganapathy; Fred H Leibach
H(+)-peptide cotransport in Madin-Darby canine kidney cells: expression and calmodulin-dependent regulation.
The American journal of physiology 1995;268(3 Pt 2):F391-7.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.
Endocrinology 1995;136(3):924-32.
1995: Puttur D Prasad; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Molecular cloning of the human placental folate transporter.
Biochemical and biophysical research communications 1995;206(2):681-7.
1994: Vadivel Ganapathy; Fred H Leibach
Human placenta: a direct target for cocaine action.
Placenta 1994;15(8):785-95.
1994: W Liu; Fred H Leibach; Vadivel Ganapathy
Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR).
Biochimica et biophysica acta 1994;1194(1):176-84.
1994: Puttur D Prasad; Sammanda Ramamoorthy; A J Moe; C H Smith; Fred H Leibach; Vadivel Ganapathy
Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells.
Biochimica et biophysica acta 1994;1223(1):71-5.
1994: Sammanda Ramamoorthy; Monte A Delmonte; Fred H Leibach; Vadivel Ganapathy
Molecular identity and calmodulin-mediated regulation of the taurine transporter in a human retinal pigment epithelial cell line.
Current eye research 1994;13(7):523-9.
1994: Puttur D Prasad; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1994;1222(2):309-14.
1994: Matthias Brandsch; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1994;1192(2):177-84.
1994: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; H Han; T Yang-Feng; Randy D Blakely; Vadivel Ganapathy
Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta.
The Biochemical journal 1994;300 ( Pt 3)():893-900.
1994: Lankupalle D Jayanthi; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells.
The Journal of biological chemistry 1994;269(20):14424-9.
1994: Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line.
The Biochemical journal 1994;299 ( Pt 1)():253-60.
1994: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.
Placenta 1994;15(3):267-78.
1994: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.
Endocrinology 1994;134(2):574-81.
1993: Lankupalle D Jayanthi; Puttur D Prasad; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter.
Biochemistry 1993;32(45):12178-85.
1993: Sammanda Ramamoorthy; D R Cool; Virendra B Mahesh; Fred H Leibach; H E Melikian; Randy D Blakely; Vadivel Ganapathy
Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding.
The Journal of biological chemistry 1993;268(29):21626-31.
1993: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Partial purification and characterization of the human placental serotonin transporter.
Placenta 1993;14(4):449-61.
1993: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Genetic evidence for role of DPP IV in intestinal hydrolysis and assimilation of prolyl peptides.
The American journal of physiology 1993;265(1 Pt 1):G81-9.
1993: Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C.
The American journal of physiology 1993;264(5 Pt 1):G939-46.
1993: Sammanda Ramamoorthy; Puttur D Prasad; P Kulanthaivel; Fred H Leibach; Randy D Blakely; Vadivel Ganapathy
Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast.
Biochemistry 1993;32(5):1346-53.
1993: Sammanda Ramamoorthy; P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Solubilization and functional reconstitution of the human placental taurine transporter.
Biochimica et biophysica acta 1993;1145(2):250-6.
1993: J W Leibach; D R Cool; Monte A Delmonte; Vadivel Ganapathy; Fred H Leibach; Y Miyamoto
Properties of taurine transport in a human retinal pigment epithelial cell line.
Current eye research 1993;12(1):29-36.
1992: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding.
The Journal of biological chemistry 1992;267(33):23632-9.
1992: C Tiruppathi; Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Constitutive expression of the taurine transporter in a human colon carcinoma cell line.
The American journal of physiology 1992;263(5 Pt 1):G625-31.
1992: B J Simon; P Kulanthaivel; G Burckhardt; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Characterization of an ATP-driven H+ pump in human placental brush-border membrane vesicles.
The Biochemical journal 1992;287 ( Pt 2)():423-30.
1992: Sammanda Ramamoorthy; D R Cool; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Reconstitution of the human placental 5-hydroxytryptamine transporter in a catalytically active form after detergent solubilization.
The Biochemical journal 1992;286 ( Pt 1)():89-95.
1992: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line.
Biochimica et biophysica acta 1992;1136(2):181-8.
1992: Sammanda Ramamoorthy; Fred H Leibach; V B Mahesh; Vadivel Ganapathy
Selective impairment of taurine transport by cyclosporin A in a human placental cell line.
Pediatric research 1992;32(1):125-7.
1992: P Kulanthaivel; TC Furesz; A J Moe; Carl H Smith; V B Mahesh; Fred H Leibach; Vadivel Ganapathy
Human placental syncytiotrophoblast expresses two pharmacologically distinguishable types of Na(+)-H+ exchangers, NHE-1 in the maternal-facing (brush border) membrane and NHE-2 in the fetal-facing (basal) membrane.
The Biochemical journal 1992;284 ( Pt 1)():33-8.
1992: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Active transport of dopamine in human placental brush-border membrane vesicles.
The American journal of physiology 1992;262(5 Pt 1):C1189-96.
1992: S Sivakami; Vadivel Ganapathy; Fred H Leibach; Y Miyamoto
The gamma-aminobutyric acid transporter and its interaction with taurine in the apical membrane of the bovine retinal pigment epithelium.
The Biochemical journal 1992;283 ( Pt 2)():391-7.
1991: Sammanda Ramamoorthy; C Tiruppathi; C N Nair; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na(+)-H+ exchangers in cultured cells.
The Biochemical journal 1991;280 ( Pt 2)():317-22.
1991: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Transport of peptides in renal brush border membrane vesicles. Suitability of 125I-labelled tyrosyl peptides as substrates.
Biochimica et biophysica acta 1991;1069(1):14-20.
1991: Vadivel Ganapathy; Y Miyamoto; C Tiruppathi; Fred H Leibach
Peptide transport across the animal cell plasma membrane: recent developments.
Indian journal of biochemistry & biophysics 1991;28(5-6):317-23.
1991: D R Cool; Fred H Leibach; V K Bhalla; Virendra B Mahesh; Vadivel Ganapathy
Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR).
The Journal of biological chemistry 1991;266(24):15750-7.
1991: Y Miyamoto; P Kulanthaivel; Fred H Leibach; Vadivel Ganapathy
Taurine uptake in apical membrane vesicles from the bovine retinal pigment epithelium.
Investigative ophthalmology & visual science 1991;32(9):2542-51.
1991: Vadivel Ganapathy; Fred H Leibach
Proton-coupled solute transport in the animal cell plasma membrane.
Current opinion in cell biology 1991;3(4):695-701.
1991: P Kulanthaivel; Y Miyamoto; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Inactivation of taurine transporter by calcium in purified human placental brush border membrane vesicles.
Placenta 1991;12(4):327-40.
1991: P Kulanthaivel; D R Cool; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line.
The Biochemical journal 1991;277 ( Pt 1)():53-8.
1991: Y Miyamoto; Y G Thompson; E F Howard; Vadivel Ganapathy; Fred H Leibach
Functional expression of the intestinal peptide-proton co-transporter in Xenopus laevis oocytes.
The Journal of biological chemistry 1991;266(8):4742-5.
1990: Y Miyamoto; P Kulanthaivel; Vadivel Ganapathy; Gary M Whitford; Fred H Leibach
Calcium-induced inhibition of taurine transport in brush-border membrane vesicles from rabbit small intestine.
Biochimica et biophysica acta 1990;1030(2):189-94.
1990: P Kulanthaivel; B J Simon; G Burckhardt; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
The ATP-binding site of the human placental H+ pump contains essential tyrosyl residues.
Biochemistry 1990;29(48):10807-13.
1990: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Kinetic evidence for a common transporter for glycylsarcosine and phenylalanylprolylalanine in renal brush-border membrane vesicles.
The Journal of biological chemistry 1990;265(25):14870-4.
1990: D R Cool; Fred H Leibach; Vadivel Ganapathy
High-affinity paroxetine binding to the human placental serotonin transporter.
The American journal of physiology 1990;259(2 Pt 1):C196-204.
1990: P Kulanthaivel; B J Simon; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
An essential role for vicinal dithiol groups in the catalytic activity of the human placental Na(+)-H+ exchanger.
Biochimica et biophysica acta 1990;1024(2):385-9.
1990: C Tiruppathi; P Kulanthaivel; Vadivel Ganapathy; Fred H Leibach
Evidence for tripeptide/H+ co-transport in rabbit renal brush-border membrane vesicles.
The Biochemical journal 1990;268(1):27-33.
1990: D R Cool; Fred H Leibach; Vadivel Ganapathy
Modulation of serotonin uptake kinetics by ions and ion gradients in human placental brush-border membrane vesicles.
Biochemistry 1990;29(7):1818-22.
1990: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Evidence for tripeptide-proton symport in renal brush border membrane vesicles. Studies in a novel rat strain with a genetic absence of dipeptidyl peptidase IV.
The Journal of biological chemistry 1990;265(4):2048-53.
1990: P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; E J Cragoe; Vadivel Ganapathy
The Na(+)-H+ exchanger of the placental brush-border membrane is pharmacologically distinct from that of the renal brush-border membrane.
The Journal of biological chemistry 1990;265(3):1249-52.
1990: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; R A Roesel; Gary M Whitford; Fred H Leibach
Hydrolysis and transport of proline-containing peptides in renal brush-border membrane vesicles from dipeptidyl peptidase IV-positive and dipeptidyl peptidase IV-negative rat strains.
The Journal of biological chemistry 1990;265(3):1476-83.
1990: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Peptidases and peptide transport in renal brush-border membrane vesicles from rats with acute renal failure.
The Journal of pharmacology and experimental therapeutics 1990;252(1):98-103.
1989: P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Tyrosine residues are essential for the activity of the human placental taurine transporter.
Biochimica et biophysica acta 1989;985(2):139-46.
1989: Vadivel Ganapathy; P Kulanthaivel; C Tiruppathi; Virendra B Mahesh; Fred H Leibach
Inactivation of the human placental serotonin transporter by tyrosyl group-specific reagents.
The Journal of pharmacology and experimental therapeutics 1989;251(1):9-15.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Active transport of taurine in rabbit jejunal brush-border membrane vesicles.
The American journal of physiology 1989;257(1 Pt 1):G65-72.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Multiple transport systems for organic cations in renal brush-border membrane vesicles.
The American journal of physiology 1989;256(4 Pt 2):F540-8.
1989: D F Balkovetz; C Tiruppathi; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes.
The Journal of biological chemistry 1989;264(4):2195-8.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Involvement of thiol groups in the function of the dipeptide/proton cotransport system in rabbit renal brush-border membrane vesicles.
Biochimica et biophysica acta 1989;978(1):25-31.
1988: C Tiruppathi; D F Balkovetz; Vadivel Ganapathy; Y Miyamoto; Fred H Leibach
A proton gradient, not a sodium gradient, is the driving force for active transport of lactate in rabbit intestinal brush-border membrane vesicles.
The Biochemical journal 1988;256(1):219-23.
1988: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Transport of guanidine in rabbit intestinal brush-border membrane vesicles.
The American journal of physiology 1988;255(1 Pt 1):G85-92.
1988: Y Miyamoto; D F Balkovetz; Vadivel Ganapathy; T Iwatsubo; M Hanano; Fred H Leibach
Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.
The Journal of pharmacology and experimental therapeutics 1988;245(3):823-8.
1988: Y Miyamoto; D F Balkovetz; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Na+ + Cl- -gradient-driven, high-affinity, uphill transport of taurine in human placental brush-border membrane vesicles.
FEBS letters 1988;231(1):263-7.
1988: Vadivel Ganapathy; Malliga E Ganapathy; C N Nair; Virendra B Mahesh; Fred H Leibach
Evidence for an organic cation-proton antiport system in brush-border membranes isolated from the human term placenta.
The Journal of biological chemistry 1988;263(10):4561-8.
1988: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Fatty acid-induced alterations in transport systems of the small intestinal brush-border membrane.
Biochemical pharmacology 1988;37(7):1399-405.
1988: Y Miyamoto; J L Coone; Vadivel Ganapathy; Fred H Leibach
Distribution and properties of the glycylsarcosine-transport system in rabbit renal proximal tubule. Studies with isolated brush-border-membrane vesicles.
The Biochemical journal 1988;249(1):247-53.
1988: Vadivel Ganapathy; Malliga E Ganapathy; C Tiruppathi; Y Miyamoto; Virendra B Mahesh; Fred H Leibach
Sodium-gradient-driven, high-affinity, uphill transport of succinate in human placental brush-border membrane vesicles.
The Biochemical journal 1988;249(1):179-84.
1988: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Role of dipeptidylpeptidase IV in renal handling of peptides.
Contributions to nephrology 1988;68():1-5.
1987: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Development of dipeptide transport in rat renal brush border membranes: studies with glycylsarcosine.
Pediatric research 1987;22(6):641-6.
1987: D F Balkovetz; Y Miyamoto; C Tiruppathi; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Inhibition of brush-border membrane Na+-H+ exchanger by loperamide.
The Journal of pharmacology and experimental therapeutics 1987;243(1):150-4.
1987: Vadivel Ganapathy; D F Balkovetz; Malliga E Ganapathy; Virendra B Mahesh; Lawrence D Devoe; Fred H Leibach
Evidence for histidyl and carboxy groups at the active site of the human placental Na+-H+ exchanger.
The Biochemical journal 1987;245(2):473-7.
1986: Vadivel Ganapathy; D F Balkovetz; Y Miyamoto; Malliga E Ganapathy; Virendra B Mahesh; Lawrence D Devoe; Fred H Leibach
Inhibition of human placental Na+-H+ exchanger by cimetidine.
The Journal of pharmacology and experimental therapeutics 1986;239(1):192-7.
1985: R A Roesel; P R Blankenship; Vadivel Ganapathy; Fred H Leibach
5-Hydroxy-L-lysine excretion in cystinuria.
Journal of inherited metabolic disease 1985;8(3):123-6.