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Dieter Leibfritz

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Jan-Bernd Hövener; Klaus Jenne; Dieter Leibfritz; Jochen Leupold; Sébastien Bär; Simon B Duckett; Jürgen Hennig; Dominik von Elverfeldt
A continuous-flow, high-throughput, high-pressure parahydrogen converter for hyperpolarization in a clinical setting.
Jelena Klawitter; Jost Klawitter; Dieter Leibfritz; Brian D Lowes; Erika Agardi; Uwe Christians; Kyler Corby; Tamas Seres
Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy.
Sébastien Bär; Jürgen Hennig; Thomas Lange; Dieter Leibfritz; Dominik von Elverfeldt; Jan-Bernd Hövener
On the spin order transfer from parahydrogen to another nucleus.

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2013: Jan-Bernd Hövener; Klaus Jenne; Dieter Leibfritz; Jochen Leupold; Sébastien Bär; Simon B Duckett; Jürgen Hennig; Dominik von Elverfeldt
A continuous-flow, high-throughput, high-pressure parahydrogen converter for hyperpolarization in a clinical setting.
NMR in biomedicine 2013;26(2):124-31.
2013: Jelena Klawitter; Jost Klawitter; Dieter Leibfritz; Brian D Lowes; Erika Agardi; Uwe Christians; Kyler Corby; Tamas Seres
Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated cell signalling with ischaemic cardiomyopathy.
Cardiovascular research 2013;97(1):66-76.
2012: Sébastien Bär; Jürgen Hennig; Thomas Lange; Dieter Leibfritz; Dominik von Elverfeldt; Jan-Bernd Hövener
On the spin order transfer from parahydrogen to another nucleus.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2012;225():25-35.
2012: Jost Klawitter; Jost Klawitter; Dieter Leibfritz; Volker Schmitz; Joshua M Thurman; Jamie Bendrick-Peart; Nina Brunner; Kyler Corby; Amanda Crunk; Charles L Edelstein; Uwe Christians
Low-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism.
Journal of proteome research 2012;11(11):5135-44.
2012: Samata M Kakkad; Dieter Leibfritz; Meiyappan Solaiyappan; Saraswati Sukumar; Pedram Argani; Zaver M Bhujwalla; LISA JACOBS; Kristine Glunde
Collagen I fiber density increases in lymph node positive breast cancers: pilot study.
Journal of biomedical optics 2012;17(11):116017.
2011: Wolfgang Dreher; Peter Erhard; Dieter Leibfritz
Fast three-dimensional proton spectroscopic imaging of the human brain at 3 T by combining spectroscopic missing pulse steady-state free precession and echo planar spectroscopic imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2011;66(6):1518-25.
2011: Sven Gottschalk; Carolyn L Cummins; Dieter Leibfritz; Uwe Christians; Leslie Z Benet; Natalie J Serkova
Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism.
Neurotoxicology 2011;32(1):50-7.
2011: Jan Willmann; Herbert Thiele; Dieter Leibfritz
Combined reversed phase HPLC, mass spectrometry, and NMR spectroscopy for a fast separation and efficient identification of phosphatidylcholines.
Journal of biomedicine & biotechnology 2011;2011():.
2010: Radovan Murín; Abolghasem Mohammadi; Bhavani S Kowtharapu; Dieter Leibfritz; Bernd Hamprecht
Metabolism of [U-(13)C]aspartate by astroglial cultures: nuclear magnetic resonance analysis of the culture media.
Neurochemical research 2010;35(12):2053-61.
2010: Miriam Schwalbe-Herrmann; Jan Willmann; Dieter Leibfritz
Separation of phospholipid classes by hydrophilic interaction chromatography detected by electrospray ionization mass spectrometry.
Journal of chromatography. A 2010;1217(32):5179-83.
2010: Saban Elitok; Saskia Trump; Hannelore Hampl; Dieter Leibfritz; Ralph Kettritz; Friedrich C Luft
Recurrent metabolic acidosis in a dialysis patient.
Kidney international 2010;78(4):425-6.
2010: Jost Klawitter; Manuel Haschke; Christine Kahle; Colleen Dingmann; Jelena Klawitter; Dieter Leibfritz; Uwe Christians
Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose.
British journal of clinical pharmacology 2010;70(2):241-51.
2010: Jelena Klawitter; Sven Gottschalk; Carsten Hainz; Dieter Leibfritz; Uwe Christians; Natalie J Serkova
Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism.
Chemical research in toxicology 2010;23(3):608-19.
2010: Jost Klawitter; Jelena Klawitter; Erich Kushner; Karen Jonscher; Jamie Bendrick-Peart; Dieter Leibfritz; Uwe Christians; Volker Schmitz
Association of immunosuppressant-induced protein changes in the rat kidney with changes in urine metabolite patterns: a proteo-metabonomic study.
Journal of proteome research 2010;9(2):865-75.
2009: Jost Klawitter; Douglas J Kominsky; Jaimi L Brown; Jost Klawitter; Uwe Christians; Dieter Leibfritz; Junia V Melo; S Gail Eckhardt; Natalie J Serkova
Metabolic characteristics of imatinib resistance in chronic myeloid leukaemia cells.
British journal of pharmacology 2009;158(2):588-600.
2009: Jeff Liddell; Claudia Zwingmann; Maike M Schmidt; Anette Thiessen; Dieter Leibfritz; Stephen R Robinson; Ralf Dringen
Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes.
Journal of neuroscience research 2009;87(12):2696-708.
2009: Radovan Murín; Abolghasem Mohammadi; Dieter Leibfritz; Bernd Hamprecht
Glial metabolism of valine.
Neurochemical research 2009;34(7):1195-203.
2009: J Klawitter; N Anderson; J Klawitter; Uwe Christians; Dieter Leibfritz; S Gail Eckhardt; Natalie J Serkova
Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.
British journal of cancer 2009;100(6):923-31.
2009: Volker Schmitz; Jost Klawitter; Jamie Bendrick-Peart; Wenzel Schoening; Gero Puhl; Manuel Haschke; Jelena Klawitter; Jeff Consoer; Christopher J Rivard; L Chan; Zung Tran; Dieter Leibfritz; Uwe Christians
Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation.
Nephron. Experimental nephrology 2009;111(4):e80-91.
2009: Jost Klawitter; Jamie Bendrick-Peart; Birgit Rudolph; Virginia Beckey; Jelena Klawitter; Manuel Haschke; Christopher Rivard; L Chan; Dieter Leibfritz; Uwe Christians; Volker Schmitz
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function.
Chemical research in toxicology 2009;22(1):118-28.
2009: Radovan Murín; Abolghasem Mohammadi; Dieter Leibfritz; Bernd Hamprecht
Glial metabolism of isoleucine.
Neurochemical research 2009;34(1):194-204.
2008: Christian Schuster; Wolfgang Dreher; Jörg Stadler; Johannes Bernarding; Dieter Leibfritz
Fast three-dimensional 1H MR spectroscopic imaging at 7 Tesla using "spectroscopic missing pulse--SSFP".
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;60(5):1243-9.
2008: Jan Willmann; Dieter Leibfritz; Herbert Thiele
Hyphenated tools for phospholipidomics.
Journal of biomolecular techniques : JBT 2008;19(3):211-6.
2008: Jost Klawitter; Christopher J Rivard; Lewis M Brown; Juan M Capasso; Nestor Almeida; Arvid B Maunsbach; Kaarina Pihakaski-Maunsbach; Tomas Berl; Dieter Leibfritz; Uwe Christians; L Chan
A metabonomic and proteomic analysis of changes in IMCD3 cells chronically adapted to hypertonicity.
Nephron. Physiology 2008;109(1):p1-10.
2008: Stefan Vielhaber; Heiko G Niessen; Grazyna Debska-Vielhaber; Alexei P Kudin; Jörg Wellmer; Jörn Kaufmann; Mircea Ariel Schönfeld; Robert Fendrich; Wieland Willker; Dieter Leibfritz; Johannes Schramm; Christian E Elger; Hans-Jochen Heinze; Wolfram S Kunz
Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.
Epilepsia 2008;49(1):40-50.
2007: Claudia Zwingmann; Dieter Leibfritz; Alan S Hazell
Nmr spectroscopic analysis of regional brain energy metabolism in manganese neurotoxicity.
Glia 2007;55(15):1610-7.
2007: Jost Klawitter; Volker Schmitz; Jelena Klawitter; Dieter Leibfritz; Uwe Christians
Development and validation of an assay for the quantification of 11 nucleotides using LC/LC-electrospray ionization-MS.
Analytical biochemistry 2007;365(2):230-9.
2007: Jan Willmann; Kerstin Mahlstedt; Dieter Leibfritz; Manfred Spraul; Herbert Thiele
Characterization of sphingomyelins in lipid extracts using a HPLC-MS-Offline-NMR method.
Analytical chemistry 2007;79(11):4188-91.
2007: Dirk Mayer; Wolfgang Dreher; Dieter Leibfritz; Daniel M Spielman
RF refocused echoes of J-coupled spin systems: effects on RARE-based spectroscopic imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(5):967-71.
2007: Heiko G Niessen; Grazyna Debska-Vielhaber; Kerstin Sander; Frank Angenstein; Albert C Ludolph; Liane Hilfert; Wieland Willker; Dieter Leibfritz; Hans-Jochen Heinze; Wolfram S Kunz; Stefan Vielhaber
Metabolic progression markers of neurodegeneration in the transgenic G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
The European journal of neuroscience 2007;25(6):1669-77.
2007: Christian Schuster; Wolfgang Dreher; Christian Geppert; Dieter Leibfritz
Fast 3D 1H spectroscopic imaging at 3 Tesla using spectroscopic missing-pulse SSFP with 3D spatial preselection.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(1):82-9.
2007: Marián Valko; Dieter Leibfritz; Jan Moncol; Mark T D Cronin; Milan Mazur; Joshua Telser
Free radicals and antioxidants in normal physiological functions and human disease.
The international journal of biochemistry & cell biology 2007;39(1):44-84.
2006: Saskia Trump; Sven Laudi; N Unruh; R Goelz; Dieter Leibfritz
1H-NMR metabolic profiling of human neonatal urine.
Magma (New York, N.Y.) 2006;19(6):305-12.
2006: Andreas Ebel; Wolfgang Dreher; Dieter Leibfritz
Effects of zero-filling and apodization on spectral integrals in discrete Fourier-transform spectroscopy of noisy data.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;182(2):330-8.
2006: Christian Geppert; Wolfgang Dreher; Matthias Althaus; Dieter Leibfritz
Fast 1H spectroscopic imaging using steady state free precession and spectral-spatial RF pulses.
Magma (New York, N.Y.) 2006;19(4):196-201.
2006: Matthias Althaus; Wolfgang Dreher; Christian Geppert; Dieter Leibfritz
Fast 3D echo planar SSFP-based 1H spectroscopic imaging: demonstration on the rat brain in vivo.
Magnetic resonance imaging 2006;24(5):549-55.
2006: Zhengchao Dong; Wolfgang Dreher; Dieter Leibfritz
Toward quantitative short-echo-time in vivo proton MR spectroscopy without water suppression.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(6):1441-6.
2005: Touraj Shokati; Claudia Zwingmann; Dieter Leibfritz
Contribution of extracellular glutamine as an anaplerotic substrate to neuronal metabolism: a re-evaluation by multinuclear NMR spectroscopy in primary cultured neurons.
Neurochemical research 2005;30(10):1269-81.
2005: Wolfgang Dreher; Dieter Leibfritz
New method for the simultaneous detection of metabolites and water in localized in vivo 1H nuclear magnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(1):190-5.
2005: Claudia Zwingmann; Dieter Leibfritz
Ammonia toxicity under hyponatremic conditions in astrocytes: de novo synthesis of amino acids for the osmoregulatory response.
Neurochemistry international 2005;47(1-2):39-50.
2004: M Gabriele Bixel; Jörn Engelmann; Wieland Willker; Bernd Hamprecht; Dieter Leibfritz
Metabolism of [U-(13)C]leucine in cultured astroglial cells.
Neurochemical research 2004;29(11):2057-67.
2004: Uwe Christians; Sven Gottschalk; Jelena Miljus; Carsten Hainz; Leslie Z Benet; Dieter Leibfritz; Natalie J Serkova
Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.
British journal of pharmacology 2004;143(3):388-96.
2004: Claudia Zwingmann; Dieter Leibfritz; Alan S Hazell
Brain energy metabolism in a sub-acute rat model of manganese neurotoxicity: an ex vivo nuclear magnetic resonance study using [1-13C]glucose.
Neurotoxicology 2004;25(4):573-87.
2004: Zhengchao Dong; Wolfgang Dreher; Dieter Leibfritz
Experimental method to eliminate frequency modulation sidebands in localized in vivo 1H MR spectra acquired without water suppression.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;51(3):602-6.
2004: Claudia Zwingmann; Nicolas Chatauret; Christopher F Rose; Dieter Leibfritz; Roger F Butterworth
Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia.
Brain research 2004;999(1):118-23.
2003: Christian Geppert; Wolfgang Dreher; Dieter Leibfritz
PRESS-based proton single-voxel spectroscopy and spectroscopic imaging with very short echo times using asymmetric RF pulses.
Magma (New York, N.Y.) 2003;16(3):144-8.
2003: Claudia Zwingmann; Dieter Leibfritz
Regulation of glial metabolism studied by 13C-NMR.
NMR in biomedicine 2003;16(6-7):370-99.
2003: Nicolas Chatauret; Claudia Zwingmann; Christopher F Rose; Dieter Leibfritz; Roger F Butterworth
Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study.
Gastroenterology 2003;125(3):815-24.
2003: Christian Meier; Wolfgang Dreher; Dieter Leibfritz
Diffusion in compartmental systems. II. Diffusion-weighted measurements of rat brain tissue in vivo and postmortem at very large b-values.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(3):510-4.
2003: Christian Meier; Wolfgang Dreher; Dieter Leibfritz
Diffusion in compartmental systems. I. A comparison of an analytical model with simulations.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(3):500-9.
2003: Wolfgang Dreher; Christian Geppert; Matthias Althaus; Dieter Leibfritz
Fast proton spectroscopic imaging using steady-state free precession methods.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(3):453-60.
2003: Claudia Zwingmann; Dieter Leibfritz; Alan S Hazell
Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(6):756-71.
2003: Dirk Mayer; Wolfgang Dreher; Dieter Leibfritz
Fast U-FLARE-based correlation-peak imaging with complete effective homonuclear decoupling.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;49(5):810-6.
2003: Olaf Beckonert; Jürgen Monnerjahn; Ulrich Bonk; Dieter Leibfritz
Visualizing metabolic changes in breast-cancer tissue using 1H-NMR spectroscopy and self-organizing maps.
NMR in biomedicine 2003;16(1):1-11.
2003: Claudia Zwingmann; Nicolas Chatauret; Dieter Leibfritz; Roger F Butterworth
Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study.
Hepatology (Baltimore, Md.) 2003;37(2):420-8.
2002: Natalie J Serkova; Paul H Donohoe; Sven Gottschalk; Carsten Hainz; Claus U Niemann; Philip E Bickler; Lawrence Litt; Leslie Z Benet; Dieter Leibfritz; Uwe Christians
Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(3):342-52.
2002: Wolfgang Dreher; Dieter Leibfritz
Fast proton spectroscopic imaging with high signal-to-noise ratio: spectroscopic RARE.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(3):523-8.
2002: Joern Engelmann; Gabriele Leyhausen; Dieter Leibfritz; Werner Geurtsen
Effect of TEGDMA on the intracellular glutathione concentration of human gingival fibroblasts.
Journal of biomedical materials research 2002;63(6):746-51.
2002: Kristine Glunde; Heiko Düssmann; Hans-Paul Juretschke; Dieter Leibfritz
Na(+)/H(+) exchange subtype 1 inhibition during extracellular acidification and hypoxia in glioma cells.
Journal of neurochemistry 2002;80(1):36-44.
2001: Natalie J Serkova; Wolfgang Jacobsen; Claus U Niemann; Lawrence Litt; Leslie Z Benet; Dieter Leibfritz; Uwe Christians
Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.
British journal of pharmacology 2001;133(6):875-85.
2001: Claudia Zwingmann; C Richter-Landsberg; Dieter Leibfritz
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.
Glia 2001;34(3):200-12.
2001: Dieter Leibfritz; Wolfgang Dreher
Magnetization transfer MRS.
NMR in biomedicine 2001;14(2):65-76.
2001: Joern Engelmann; Gabriele Leyhausen; Dieter Leibfritz; Werner Geurtsen
Metabolic effects of dental resin components in vitro detected by NMR spectroscopy.
Journal of dental research 2001;80(3):869-75.
2001: Wolfgang Dreher; E Busch; Dieter Leibfritz
Changes in apparent diffusion coefficients of metabolites in rat brain after middle cerebral artery occlusion measured by proton magnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2001;45(3):383-9.
2000: Claudia Zwingmann; C Richter-Landsberg; A Brand; Dieter Leibfritz
NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism.
Glia 2000;32(3):286-303.
2000: Wieland Willker; Dieter Leibfritz
Lipid oxidation in blood plasma of patients with neurological disorders.
Brain research bulletin 2000;53(4):437-43.
2000: Wolfgang Dreher; Dieter Leibfritz
A new method for fast proton spectroscopic imaging: spectroscopic GRASE.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;44(5):668-72.
2000: Claudia Zwingmann; U Flögel; J Pfeuffer; Dieter Leibfritz
Effects of ammonia exposition on glioma cells: changes in cell volume and organic osmolytes studied by diffusion-weighted and high-resolution NMR spectroscopy.
Developmental neuroscience 2000;22(5-6):463-71.
2000: D Mayer; Wolfgang Dreher; Dieter Leibfritz
Fast echo planar based correlation-peak imaging: demonstration on the rat brain in vivo.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;44(1):23-8.
2000: Natalie J Serkova; Lawrence Litt; Dieter Leibfritz; Bernard Hausen; R E Morris; Tom L James; Leslie Z Benet; Uwe Christians
The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates.
British journal of pharmacology 2000;129(3):485-92.
2000: Andreas Ebel; Wolfgang Dreher; Dieter Leibfritz
A fast variant of (1)H spectroscopic U-FLARE imaging using adjusted chemical shift phase encoding.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;142(2):241-53.
2000: Dieter Leibfritz; J Pfeuffer; U Flögel; C Meier; Stefan Broer
Cell volume and water exchange in neural cells monitored by diffusion weighted 1H NMR spectroscopy.
Progress in brain research 2000;125():255-63.
1999: A Brand; Dieter Leibfritz; C Richter-Landsberg
Oxidative stress-induced metabolic alterations in rat brain astrocytes studied by multinuclear NMR spectroscopy.
Journal of neuroscience research 1999;58(4):576-85.
1999: Bernd Kühn; Wolfgang Dreher; Dieter Leibfritz; Martin Heller
Homonuclear uncoupled 1H-spectroscopy of the human brain using weighted accumulation schemes.
Magnetic resonance imaging 1999;17(8):1193-201.
1999: J Henke; Joern Engelmann; B Kutscher; G Nssner; J Engel; Rainer Voegeli; Dieter Leibfritz
Changes of intracellular calcium, fatty acids and phospholipids during miltefosine-induced apoptosis monitored by fluorescence- and 13C NMR-spectroscopy.
Anticancer research 1999;19(5B):4027-32.
1999: Stephan Verleysdonk; H Martin; Wieland Willker; Dieter Leibfritz; Bernd Hamprecht
Rapid uptake and degradation of glycine by astroglial cells in culture: synthesis and release of serine and lactate.
Glia 1999;27(3):239-48.
1999: S A Roell; Wolfgang Dreher; Dieter Leibfritz
Combining CW and pulsed saturation allows in vivo quantitation of magnetization transfer observed for total creatine by (1)H-NMR-spectroscopy of rat brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(2):222-7.
1999: Wolfgang Dreher; Dieter Leibfritz
Improved proton spectroscopic U-FLARE imaging for the detection of coupled resonances in the rat brain in vivo.
Magnetic resonance imaging 1999;17(4):611-21.
1999: Natalie J Serkova; Lawrence Litt; Tom L James; Wolfgang Sadée; Dieter Leibfritz; Leslie Z Benet; Uwe Christians
Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy.
The Journal of pharmacology and experimental therapeutics 1999;289(2):800-6.
1999: Wolfgang Dreher; Dieter Leibfritz
Detection of homonuclear decoupled in vivo proton NMR spectra using constant time chemical shift encoding: CT-PRESS.
Magnetic resonance imaging 1999;17(1):141-50.
1998: U Flögel; Dieter Leibfritz
Alterations in glial cell metabolism during recovery from chronic osmotic stress.
Neurochemical research 1998;23(12):1553-61.
1998: J Pfeuffer; Stefan Broer; Angelika Bröer; M Lechte; U Flögel; Dieter Leibfritz
Expression of aquaporins in Xenopus laevis oocytes and glial cells as detected by diffusion-weighted 1H NMR spectroscopy and photometric swelling assay.
Biochimica et biophysica acta 1998;1448(1):27-36.
1998: J Pfeuffer; Wolfgang Dreher; E Sykova; Dieter Leibfritz
Water signal attenuation in diffusion-weighted 1H NMR experiments during cerebral ischemia: influence of intracellular restrictions, extracellular tortuosity, and exchange.
Magnetic resonance imaging 1998;16(9):1023-32.
1998: A Brand; C Richter-Landsberg; U Flögel; Wieland Willker; Dieter Leibfritz
Rat brain primary neurons immobilized in basement membrane gel threads: an improved method for on-line 13C NMR spectroscopy of live cells.
Brain research. Brain research protocols 1998;3(2):183-91.
1998: A Brand; S Gil; Dieter Leibfritz; Ephraim Yavin
Direct administration and utilization of [1-13C]glucose by fetal brain and liver tissues under normal and ischemic conditions: 1H, 31P, and 13C NMR studies.
Journal of neuroscience research 1998;54(1):97-108.
1998: A Brand; Dieter Leibfritz; Bernd Hamprecht; Ralf Dringen
Metabolism of cysteine in astroglial cells: synthesis of hypotaurine and taurine.
Journal of neurochemistry 1998;71(2):827-32.
1998: Wolfgang Dreher; Bernd Kühn; ML Gyngell; E Busch; T Niendorf; Konstantin-Alexander Hossmann; Dieter Leibfritz
Temporal and regional changes during focal ischemia in rat brain studied by proton spectroscopic imaging and quantitative diffusion NMR imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1998;39(6):878-88.
1998: S A Roell; Wolfgang Dreher; E Busch; Dieter Leibfritz
Magnetization transfer attenuates metabolite signals in tumorous and contralateral animal brain: in vivo observations by proton NMR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1998;39(5):742-8.
1998: Wieland Willker; U Flögel; Dieter Leibfritz
A 1H/13C inverse 2D method for the analysis of the polyamines putrescine, spermidine and spermine in cell extracts and biofluids.
NMR in biomedicine 1998;11(2):47-54.
1998: J Pfeuffer; U Flögel; Wolfgang Dreher; Dieter Leibfritz
Restricted diffusion and exchange of intracellular water: theoretical modelling and diffusion time dependence of 1H NMR measurements on perfused glial cells.
NMR in biomedicine 1998;11(1):19-31.
1998: J Pfeuffer; U Flögel; Dieter Leibfritz
Monitoring of cell volume and water exchange time in perfused cells by diffusion-weighted 1H NMR spectroscopy.
NMR in biomedicine 1998;11(1):11-8.
1998: Ralf Dringen; Stephan Verleysdonk; Bernd Hamprecht; Wieland Willker; Dieter Leibfritz; A Brand
Metabolism of glycine in primary astroglial cells: synthesis of creatine, serine, and glutathione.
Journal of neurochemistry 1998;70(2):835-40.
1998: Claudia Zwingmann; A Brand; C Richter-Landsberg; Dieter Leibfritz
Multinuclear NMR spectroscopy studies on NH4Cl-induced metabolic alterations and detoxification processes in primary astrocytes and glioma cells.
Developmental neuroscience 1998;20(4-5):417-26.
1997: Natalie J Serkova; Uwe Christians; U Flögel; J Pfeuffer; Dieter Leibfritz
Assessment of the mechanism of astrocyte swelling induced by the macrolide immunosuppressant sirolimus using multinuclear nuclear magnetic resonance spectroscopy.
Chemical research in toxicology 1997;10(12):1359-63.
1997: A Brand; C Richter-Landsberg; Dieter Leibfritz
Metabolism of acetate in rat brain neurons, astrocytes and cocultures: metabolic interactions between neurons and glia cells, monitored by NMR spectroscopy.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(5):645-57.
1997: U Flögel; Wieland Willker; Dieter Leibfritz
Determination of de novo synthesized amino acids in cellular proteins revisited by 13C NMR spectroscopy.
NMR in biomedicine 1997;10(2):50-8.
1997: J Benters; U Flögel; T Schäfer; Dieter Leibfritz; S Hechtenberg; Detmar Beyersmann
Study of the interactions of cadmium and zinc ions with cellular calcium homoeostasis using 19F-NMR spectroscopy.
The Biochemical journal 1997;322 ( Pt 3)():793-9.
1997: Wieland Willker; U Flögel; Dieter Leibfritz
Ultra-high-resolved HSQC spectra of multiple- 13C-labeled biofluids.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;125(1):216-9.
1997: A Brand; Dieter Leibfritz; H Wolburg; C Richter-Landsberg
Interactions of triethyltin-chloride (TET) with the energy metabolism of cultured rat brain astrocytes: studies by multinuclear magnetic resonance spectroscopy.
Neurochemical research 1997;22(2):123-31.
1996: Natalie J Serkova; A Brand; Uwe Christians; Dieter Leibfritz
Evaluation of the effects of immunosuppressants on neuronal and glial cells in vitro by multinuclear magnetic resonance spectroscopy.
Biochimica et biophysica acta 1996;1314(1-2):93-104.
1996: J Engelmann; J Henke; Wieland Willker; B Kutscher; G Nössner; J Engel; Dieter Leibfritz
Early stage monitoring of miltefosine induced apoptosis in KB cells by multinuclear NMR spectroscopy.
Anticancer research 1996;16(3B):1429-39.
1996: J Henke; Wieland Willker; J Engelmann; Dieter Leibfritz
Combined extraction techniques of tumour cells and lipid/phospholipid assignment by two dimensional NMR spectroscopy.
Anticancer research 1996;16(3B):1417-27.
1996: Dieter Leibfritz
An introduction to the potential of 1H-, 31P- and 13C-NMR-spectroscopy.
Anticancer research 1996;16(3B):1317-24.
1996: Bernd Kühn; Wolfgang Dreher; David G Norris; Dieter Leibfritz
Fast proton spectroscopic imaging employing k-space weighting achieved by variable repetition times.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1996;35(4):457-64.
1996: Rick M Dijkhuizen; M van Lookeren Campagne; T Niendorf; Wolfgang Dreher; A van der Toorn; M Hoehn-Berlage; H B Verheul; Cornelis A F Tulleken; Dieter Leibfritz; Konstantin-Alexander Hossmann; Klaas Nicolay
Status of the neonatal rat brain after NMDA-induced excitotoxic injury as measured by MRI, MRS and metabolic imaging.
NMR in biomedicine 1996;9(2):84-92.
1996: P M Alves; U Flögel; A Brand; Dieter Leibfritz; Manuel J T Carrondo; Helena Santos; U Sonnewald
Immobilization of primary astrocytes and neurons for online monitoring of biochemical processes by NMR.
Developmental neuroscience 1996;18(5-6):478-83.
1996: U Flögel; Wieland Willker; J Engelmann; T Niendorf; Dieter Leibfritz
Adaptation of cellular metabolism to anisosmotic conditions in a glial cell line, as assessed by 13C-NMR spectroscopy.
Developmental neuroscience 1996;18(5-6):449-59.
1995: Wolfgang Dreher; Dieter Leibfritz
On the use of two-dimensional-J NMR measurements for in vivo proton MRS: measurement of homonuclear decoupled spectra without the need for short echo times.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1995;34(3):331-7.
1995: T Reese; David G Norris; Dieter Leibfritz
A fast method for in vivo lactate imaging.
NMR in biomedicine 1995;8(5):225-31.
1995: U Flögel; T Niendorf; N Serkowa; A Brand; J Henke; Dieter Leibfritz
Changes in organic solutes, volume, energy state, and metabolism associated with osmotic stress in a glial cell line: a multinuclear NMR study.
Neurochemical research 1995;20(7):793-802.
1995: Wolfgang Dreher; Dieter Leibfritz
Parametric multiecho proton spectroscopic imaging: application to the rat brain in vivo.
Magnetic resonance imaging 1995;13(5):753-61.
1994: T Niendorf; David G Norris; Dieter Leibfritz
Detection of apparent restricted diffusion in healthy rat brain at short diffusion times.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;32(5):672-7.
1994: David G Norris; T Niendorf; Dieter Leibfritz
Health and infarcted brain tissues studied at short diffusion times: the origins of apparent restriction and the reduction in apparent diffusion coefficient.
NMR in biomedicine 1994;7(7):304-10.
1994: U Flögel; Wieland Willker; Dieter Leibfritz
Regulation of intracellular pH in neuronal and glial tumour cells, studied by multinuclear NMR spectroscopy.
NMR in biomedicine 1994;7(4):157-66.
1994: Wolfgang Dreher; Dieter Leibfritz
Double-echo multislice proton spectroscopic imaging using Hadamard slice encoding.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;31(6):596-600.
1994: Wolfgang Dreher; David G Norris; Dieter Leibfritz
Magnetization transfer affects the proton creatine/phosphocreatine signal intensity: in vivo demonstration in the rat brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;31(1):81-4.
1994: David G Norris; T Niendorf; M Hoehn-Berlage; K Kohno; E J Schneider; P Hainz; M Hropot; Dieter Leibfritz
Incidence of apparent restricted diffusion in three different models of cerebral infarction.
Magnetic resonance imaging 1994;12(8):1175-82.
1993: H Assadnazari; Guido Zimmer; H J Freisleben; W Werk; Dieter Leibfritz
Cardioprotective efficiency of dihydrolipoic acid in working rat hearts during hypoxia and reoxygenation. 31P nuclear magnetic resonance investigations.
Arzneimittel-Forschung 1993;43(4):425-32.
1993: U Wollborn; R M Brunne; J Harting; G Hölzemann; Dieter Leibfritz
Comparative conformational analysis and in vitro pharmacological evaluation of three cyclic hexapeptide NK-2 antagonists.
International journal of peptide and protein research 1993;41(4):376-84.
1993: U Flögel; Dieter Leibfritz
Response of 3T3 cells on stimulation of adenylate cyclase by forskolin, studied by multinuclear NMR spectroscopy.
Biological chemistry Hoppe-Seyler 1993;374(3):211-6.
1993: Peter Börnert; David G Norris; H Koch; Wolfgang Dreher; H Reichelt; Dieter Leibfritz
Fast perfluorocarbon imaging using 19F U-FLARE.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1993;29(2):226-34.
1993: H Koch; I Okyayuz-Baklouti; D Norris; Herbert Kogler; Dieter Leibfritz
Correlation of function and energy metabolism in rat ischemic skeletal muscle by 31P-NMR spectroscopy: effects of torbafylline.
Journal of medicine 1993;24(1):47-66.
1993: David G Norris; M Hoehn-Berlage; F Wittlich; T Back; Dieter Leibfritz
Dynamic imaging with T2* contrast using U-FLARE.
Magnetic resonance imaging 1993;11(7):921-4.
1993: F Koschorek; W Offermann; J Stelten; W E Braunsdorf; U Steller; H Gremmel; Dieter Leibfritz
High-resolution 1H NMR spectroscopy of cerebrospinal fluid in spinal diseases.
Neurosurgical review 1993;16(4):307-15.
1993: A Brand; C Richter-Landsberg; Dieter Leibfritz
Multinuclear NMR studies on the energy metabolism of glial and neuronal cells.
Developmental neuroscience 1993;15(3-5):289-98.
1992: R Callies; Rolf Altenburger; S Abarzua; A Mayer; L Horst Grimme; Dieter Leibfritz
In situ nuclear magnetic resonance of N pulse labels monitors different routes for nitrogen assimilation.
Plant physiology 1992;100(3):1584-6.
1992: R M Brunne; Dieter Leibfritz
Conformational regions of Boc-Ala-Aib-Ala-OMe. Sampling with molecular dynamics simulations using time averaging of distance restraints.
International journal of peptide and protein research 1992;40(5):401-6.
1992: David G Norris; Peter Börnert; T Reese; Dieter Leibfritz
On the application of ultra-fast RARE experiments.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;27(1):142-64.
1992: A Brand; J Engelmann; Dieter Leibfritz
A 13C NMR study on fluxes into the TCA cycle of neuronal and glial tumor cell lines and primary cells.
Biochimie 1992;74(9-10):941-8.
1990: David G Norris; U Böttcher; Dieter Leibfritz
A simple method of generating variable T1 contrast images using temporally reordered phase encoding.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1990;15(3):483-90.
1990: H Kugel; A Mayer; G O Kirst; Dieter Leibfritz
The energy requirements of pH homoeostasis define the limits of pH regulation--a model.
Biochimica et biophysica acta 1990;1054(1):33-40.
1990: D Stryjewski; Dieter Leibfritz
Improved metabolite editing by the 1D soft COSY technique with 270 degrees Gaussian-shaped pulses.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1990;15(2):340-5.
1990: Haripalsingh Sonawat; Dieter Leibfritz; J Engel; P Hilgard
Biotransformation of mafosfamide in P388 mice leukemia cells: intracellular 31P-NMR studies.
Biochimica et biophysica acta 1990;1052(1):36-41.
1990: D Stryjewski; H Oschkinat; Dieter Leibfritz
Detection of metabolites in body fluids and biological tissue by a 1D soft COSY technique.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1990;13(1):158-61.
1990: Dieter Leibfritz
[Medical applications of NMR spectroscopy].
Biomedizinische Technik. Biomedical engineering 1990;35 Suppl 3():256-7.
1989: J H Langkowski; J Wieland; H Bomsdorf; Dieter Leibfritz; M Westphal; W Offermann; R Maas
Pre-operative localized in vivo proton spectroscopy in cerebral tumors at 4.0 Tesla--first results.
Magnetic resonance imaging 1989;7(5):547-55.
1989: F Koschorek; H Gremmel; J Stelten; W Offermann; E Krüger; Dieter Leibfritz
Characterization of CNS lesions by using high-resolution 1H MR spectroscopy of CSF: preliminary results.
AJNR. American journal of neuroradiology 1989;10(3):523-7.
1988: Axel Haase; Dieter Leibfritz; W Werk
31P FLASH NMR imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1988;7(3):358-63.
1988: F Koschorek; H Gremmel; J Stelten; W Offermann; Dieter Leibfritz
Cerebrospinal fluid: detection of tumors and disk herniations with MR spectroscopy.
Radiology 1988;167(3):813-6.
1987: U Pilatus; A Mayer; W Offermann; Dieter Leibfritz
Sodium binding to and protonation of ATP: a multinuclear magnetic double resonance study at 8.46 tesla.
Biochimica et biophysica acta 1987;926(1):106-13.
1987: R Kasperk; C Kasperk; W Werk; Dieter Leibfritz
31P magnetic resonance studies of isolated rat small intestine: influence of preservation in Ringer's lactate, Eurocollins, and Bretschneider solution.
Transplantation proceedings 1987;19(5):4122.
1987: W Offermann; W Kuhn; S Soboll; T Ishikawa; Dieter Leibfritz
The in vivo contour plot. An improved representation of stimulus experiments.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;4(6):507-16.