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Leslie Leinwand

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Hypertrophic Cardiomyopathy

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TOP 3
Leslie A Leinwand; Brooke C Harrison
Young at heart.
Eva Andres-Mateos; Heinrich Brinkmeier; Tyesha N Burks; Diego Alvarez de la Rosa; Daniel C Files; Erika Finanger Hedderick; Michael Föller; Ivan Hernandez-Diaz; Christophe Hourdé; Dietmar Kuhl; Florian Lang; Leslie A Leinwand; Benjamin Lin; Brian M Lin; Tom G Marr; RUTH MARX-RATTNER; Rebeca Mejias; Jessica L Simmers; Arshia Soleimani; Martin Steinberger; Dana K Vaughan; Silke Vogelsang; Ronald D Cohn
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy.
Jayakrishnan Nandakumar; Ina Weidenfeld; Arthur J Zaug; Caitlin F Bell; Leslie A Leinwand; Thomas R Cech
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.

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All Publications

2013: Leslie A Leinwand; Brooke C Harrison
Young at heart.
Cell 2013;153(4):743-5.
2013: Eva Andres-Mateos; Heinrich Brinkmeier; Tyesha N Burks; Diego Alvarez de la Rosa; Daniel C Files; Erika Finanger Hedderick; Michael Föller; Ivan Hernandez-Diaz; Christophe Hourdé; Dietmar Kuhl; Florian Lang; Leslie A Leinwand; Benjamin Lin; Brian M Lin; Tom G Marr; RUTH MARX-RATTNER; Rebeca Mejias; Jessica L Simmers; Arshia Soleimani; Martin Steinberger; Dana K Vaughan; Silke Vogelsang; Ronald D Cohn
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy.
EMBO molecular medicine 2013;5(1):80-91.
2012: Jayakrishnan Nandakumar; Ina Weidenfeld; Arthur J Zaug; Caitlin F Bell; Leslie A Leinwand; Thomas R Cech
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.
Nature 2012;492(7428):285-9.
2012: Jorge L Ruas; James P White; Jun Wu; Zhen Yan; Kevin T Brannan; Jennifer L Estall; Nicholas P Greene; Brooke C Harrison; Brian Irving; Sandra Kleiner; Ian R Lanza; Leslie A Leinwand; K Sreekumaran Nair; Mitsuharu Okutsu; Rajesh R Rao; Kyle A Rasbach; Bruce M Spiegelman
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.
Cell 2012;151(6):1319-31.
2012: Pippa F Cosper; Pamela A Harvey; Leslie A Leinwand
Interferon-γ causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis.
The American journal of pathology 2012;181(6):2038-46.
2012: John C Deacon; Michael A Geeves; Marieke J Bloemink; Heresh Rezavandi; Leslie A Leinwand
Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors.
Cellular and molecular life sciences : CMLS 2012;69(24):4239-55.
2012: Robert C Thompson; Ada Buvoli; Massimo Buvoli; Leslie A Leinwand
Myosin filament assembly requires a cluster of four positive residues located in the rod domain.
FEBS letters 2012;586(19):3008-12.
2012: Christopher D Haines; Pamela A Harvey; John P Konhilas; Elizabeth D Luczak; Brian L Stauffer; Peter A Watson; Kristen K B Barthel; Leslie A Leinwand
Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease.
Endocrinology 2012;153(9):4470-9.
2012: Christopher D Haines; Pamela A Harvey; Leslie A Leinwand
Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner.
Endocrinology 2012;153(9):4480-90.
2012: Espen E Spangenburg; Paige C Geiger; Leslie A Leinwand; Dawn A Lowe
Regulation of physiological and metabolic function of muscle by female sex steroids.
Medicine and science in sports and exercise 2012;44(9):1653-62.
2012: Fan Yeung; Matthew L Bell; Eunhee Chung; Martin G Guess; Leslie A Leinwand
Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.
Nucleic acids research 2012;40(15):7303-18.
2012: Leslie A Leinwand; Jil C Tardiff; Carol C Gregorio
Mutations in the sensitive giant titin result in a broken heart.
Circulation research 2012;111(2):158-61.
2012: John C Deacon; Michael A Geeves; Marieke J Bloemink; Heresh Rezavandi; Leslie A Leinwand
Identification of functional differences between recombinant human α and β cardiac myosin motors.
Cellular and molecular life sciences : CMLS 2012;69(13):2261-77.
2012: Pippa F Cosper; Leslie A Leinwand
Myosin heavy chain is not selectively decreased in murine cancer cachexia.
International journal of cancer. Journal international du cancer 2012;130(11):2722-7.
2012: Eunhee Chung; Fan Yeung; Leslie A Leinwand
Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(9):1564-75.
2012: Massimo Buvoli; Ada Buvoli; Leslie A Leinwand
Effects of pathogenic proline mutations on myosin assembly.
Journal of molecular biology 2012;415(5):807-18.
2012: Eva Andres-Mateos; Tyesha N Burks; David L Huso; Leslie A Leinwand; Benjamin Lin; Brian M Lin; Tom G Marr; RUTH MARX-RATTNER; Rebeca Mejias; Dana K Merriman; Arshia Soleimani; RICHARD ZELLARS; Yonggang Zhang; Ronald D Cohn
Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels.
PloS one 2012;7(11):e48884.
2012: Eunhee Chung; Joseph Heimiller; Leslie A Leinwand
Distinct cardiac transcriptional profiles defining pregnancy and exercise.
PloS one 2012;7(7):e42297.
2012: Huan Wang; Sarah M Haeger; April M Kloxin; Leslie A Leinwand; Kristi S Anseth
Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus.
PloS one 2012;7(7):e39969.
2011: Cecilia A Riquelme; Stephen M Secor; Christopher E Wall; Brooke C Harrison; Jason A Magida; Thomas G Marr; Leslie A Leinwand
Fatty acids identified in the Burmese python promote beneficial cardiac growth.
Science (New York, N.Y.) 2011;334(6055):528-31.
2011: Pamela A Harvey; Leslie A Leinwand
The cell biology of disease: cellular mechanisms of cardiomyopathy.
The Journal of cell biology 2011;194(3):355-65.
2011: Douglas D Lemon; Todd R Horn; Maria A Cavasin; Mark Y Jeong; Kurt W Haubold; Carlin S Long; David C Irwin; Sylvia A McCune; Eunhee Chung; Leslie A Leinwand; Timothy A McKinsey
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Journal of molecular and cellular cardiology 2011;51(1):41-50.
2011: Elizabeth D Luczak; Brian L Stauffer; Kristen K B Barthel; Tom H Cheung; John P Konhilas; Leslie A Leinwand
Remodeling the cardiac transcriptional landscape with diet.
Physiological genomics 2011;43(12):772-80.
2011: Leslie A Leinwand; Richard L Moss
Medicine. Chemically tuned myosin motors.
Science (New York, N.Y.) 2011;331(6023):1392-3.
2011: Pippa F Cosper; Leslie A Leinwand
Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner.
Cancer research 2011;71(5):1710-20.
2011: Brooke C Harrison; David L Allen; Leslie A Leinwand
IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men.
Skeletal muscle 2011;1(1):5.
2011: Christopher E Wall; Steven Cozza; Cecilia A Riquelme; W Richard McCombie; Joseph K Heimiller; Thomas G Marr; Leslie A Leinwand
Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation.
Physiological genomics 2011;43(2):69-76.
2010: Micah Hamady; Massimo Buvoli; Leslie A Leinwand; Rob Knight
Estimate of the abundance of cardiomyopathic mutations in the β-myosin gene.
International journal of cardiology 2010;144(1):124-6.
2010: John P Konhilas; Dana M Boucek; Todd R Horn; Gary L Johnson; Leslie A Leinwand
The role of MEKK1 in hypertrophic cardiomyopathy.
International heart journal 2010;51(4):277-84.
2010: Thomas Z Armel; Leslie A Leinwand
Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes.
Journal of molecular and cellular cardiology 2010;48(5):1007-13.
2010: Matthew L Bell; Massimo Buvoli; Leslie A Leinwand
Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping.
Molecular and cellular biology 2010;30(8):1937-45.
2010: Daniel I Resnicow; John C Deacon; Hans M Warrick; James A Spudich; Leslie A Leinwand
Functional diversity among a family of human skeletal muscle myosin motors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(3):1053-8.
2010: Thomas Z Armel; Leslie A Leinwand
A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype.
Biochemical and biophysical research communications 2010;391(1):352-6.
2010: Mark Hutchinson; Yingning Zhang; Mitesh Shridhar; John H Evans; Madison M Buchanan; Tina X Zhao; Peter F Slivka; Benjamen D Coats; Niloofar Rezvani; Julie Wieseler; Travis S Hughes; Kyle E Landgraf; Stefanie Chan; Stephanie Fong; Simon Phipps; Joseph J Falke; Leslie A Leinwand; Steven F Maier; Hang Yin; Kenner C Rice; Linda R Watkins
Evidence that opioids may have toll-like receptor 4 and MD-2 effects.
Brain, behavior, and immunity 2010;24(1):83-95.
2009: Julie A Benton; Hanna B Kern; Leslie A Leinwand; Peter D Mariner; Kristi S Anseth
Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1950-7.
2009: Evan M Sloane; S Langer; B Jekich; J Mahoney; T Hughes; M Frank; W Seibert; G Huberty; B Coats; J Harrison; D Klinman; Stephen Poole; S Maier; K Johnson; Raymond A Chavez; Linda R Watkins; Leslie A Leinwand; E Milligan
Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain.
Gene therapy 2009;16(10):1210-22.
2009: Travis S Hughes; Stephen J Langer; Salla I Virtanen; Raymond A Chavez; Linda R Watkins; Erin D Milligan; Leslie A Leinwand
Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression.
The journal of gene medicine 2009;11(9):782-90.
2009: Stephen W Luckey; Lori A Walker; Tyson Smyth; Jason Mansoori; Antke Messmer-Kratzsch; Anthony Rosenzweig; Eric N Olson; Leslie A Leinwand
The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy.
Journal of molecular and cellular cardiology 2009;46(5):739-47.
2009: Thomas Z Armel; Leslie A Leinwand
Mutations in the beta-myosin rod cause myosin storage myopathy via multiple mechanisms.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6291-6.
2009: Travis S Hughes; Stephen J Langer; Kirk W Johnson; Raymond A Chavez; Linda R Watkins; Erin D Milligan; Leslie A Leinwand
Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):88-94.
2009: Evan M Sloane; Annemarie Ledeboer; W Seibert; B Coats; M van Strien; Steven F Maier; Kirk W Johnson; Raymond A Chavez; Linda R Watkins; Leslie A Leinwand; Erin D Milligan; A M Van Dam
Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy.
Brain, behavior, and immunity 2009;23(1):92-100.
2009: Elizabeth D Luczak; Leslie A Leinwand
Sex-based cardiac physiology.
Annual review of physiology 2009;71():1-18.
2008: Eunhee Chung; Leslie A Leinwand
Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins.
Circulation research 2008;103(12):1351-3.
2008: Massimo Buvoli; Micah Hamady; Leslie A Leinwand; Rob Knight
Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations.
Trends in cardiovascular medicine 2008;18(4):141-9.
2008: Dalan R Jensen; Leslie A Knaub; John P Konhilas; Leslie A Leinwand; Paul S MacLean; Robert H Eckel
Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?
Journal of lipid research 2008;49(4):870-9.
2008: Daniel I Resnicow; Anneka M Hooft; Brooke C Harrison; Josh E Baker; Leslie A Leinwand
GFP fails to inhibit actin-myosin interactions in vitro.
Nature methods 2008;5(3):212-3; author reply 213-4.
2008: Brooke C Harrison; Leslie A Leinwand
Fighting fat with muscle: bulking up to slim down.
Cell metabolism 2008;7(2):97-8.
2007: John P Konhilas; Leslie A Leinwand
The effects of biological sex and diet on the development of heart failure.
Circulation 2007;116(23):2747-59.
2007: Peter A Watson; Jane E B Reusch; Sylvia A McCune; Leslie A Leinwand; Stephen W Luckey; John P Konhilas; David A Brown; Adam J Chicco; Genevieve C Sparagna; Carlin S Long; Russell L Moore
Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H246-59.
2007: Annemarie Ledeboer; Brian M Jekich; Evan M Sloane; John H Mahoney; Stephen J Langer; Erin D Milligan; David Martin; Steven F Maier; Kirk W Johnson; Leslie A Leinwand; Raymond A Chavez; Linda R Watkins
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.
Brain, behavior, and immunity 2007;21(5):686-98.
2007: Danielle S W Benoit; Margaret C Tripodi; James O Blanchette; Steve J Langer; Leslie A Leinwand; Kristi S Anseth
Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells.
Journal of biomedical materials research. Part A 2007;81(2):259-68.
2007: Leslie A Leinwand
Molecular events underlying pregnancy-induced cardiomyopathy.
Cell 2007;128(3):437-8.
2007: Stephen W Luckey; Jason Mansoori; Kelly Fair; Christopher L Antos; Eric N Olson; Leslie A Leinwand
Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males.
American journal of physiology. Heart and circulatory physiology 2007;292(2):H838-45.
2007: Jamie Sheren; Stephen J Langer; Leslie A Leinwand
A randomized library approach to identifying functional lox site domains for the Cre recombinase.
Nucleic acids research 2007;35(16):5464-73.
2007: Massimo Buvoli; Ada Buvoli; Leslie A Leinwand
Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse.
PloS one 2007;2(5):e427.
2006: Erin D Milligan; Evan M Sloane; Stephen J Langer; Travis S Hughes; Brian M Jekich; Matthew G Frank; John H Mahoney; Lindsay H Levkoff; Steven F Maier; Pedro E Cruz; Terence R Flotte; Kirk W Johnson; Melissa M Mahoney; Raymond A Chavez; Leslie A Leinwand; Linda R Watkins
Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.
Pain 2006;126(1-3):294-308.
2006: Erin D Milligan; Ryan G Soderquist; Stephanie M Malone; John H Mahoney; Travis S Hughes; Stephen J Langer; Evan M Sloane; Steven F Maier; Leslie A Leinwand; Linda R Watkins; Melissa J Mahoney
Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.
Neuron glia biology 2006;2(4):293-308.
2006: Carmen C Sucharov; Stephen Langer; Michael R Bristow; Leslie A Leinwand
Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A.
American journal of physiology. Cell physiology 2006;291(5):C1029-37.
2006: Norbert F Voelkel; Robert A Quaife; Leslie A Leinwand; Robyn J Barst; Michael D McGoon; Daniel R Meldrum; Jocelyn Dupuis; Carlin S Long; Lewis J Rubin; Frank W Smart; Yuichiro J Suzuki; Mark Gladwin; Elizabeth M Denholm; Dorothy B Gail
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure.
Circulation 2006;114(17):1883-91.
2006: Aron M Geurts; Lara S Collier; Jennifer L Geurts; Leann L Oseth; Matthew L Bell; David Mu; Robert Lucito; Susan A Godbout; Laura E Green; Scott W Lowe; Betsy A Hirsch; Leslie A Leinwand; David Largaespada
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers.
PLoS genetics 2006;2(9):e156.
2006: Carmen C Sucharov; Peter D Mariner; Karin Nunley; Carlin Long; Leslie A Leinwand; Michael R Bristow
A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction.
American journal of physiology. Heart and circulatory physiology 2006;291(3):H1299-308.
2006: Doris Heidysch Beylkin; David L Allen; Leslie A Leinwand
MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes.
Developmental biology 2006;294(2):541-53.
2006: John P Konhilas; Leslie A Leinwand
Partnering up for cardiac hypertrophy.
Circulation research 2006;98(8):985-7.
2006: John P Konhilas; Peter A Watson; Alexander H Maass; Dana M Boucek; Todd Horn; Brian L Stauffer; Stephen W Luckey; Paul Rosenberg; Leslie A Leinwand
Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
Circulation research 2006;98(4):540-8.
2006: Briana K Dennehey; Leslie A Leinwand; Kenneth S Krauter
Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.
Journal of muscle research and cell motility 2006;27(8):559-75.
2006: Brian L Stauffer; John P Konhilas; Elizabeth D Luczak; Leslie A Leinwand
Soy diet worsens heart disease in mice.
The Journal of clinical investigation 2006;116(1):209-16.
2005: Melinda C Cushing; Michael P Jaeggli; Kristyn S Masters; Leslie A Leinwand; Kristi S Anseth
Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells.
Journal of biomedical materials research. Part A 2005;75(1):232-41.
2005: John P Konhilas; Ulrika widegren; David L Allen; Angelika C Paul; Allison Cleary; Leslie A Leinwand
Loaded wheel running and muscle adaptation in the mouse.
American journal of physiology. Heart and circulatory physiology 2005;289(1):H455-65.
2005: Kristyn S Masters; Darshita N Shah; Leslie A Leinwand; Kristi S Anseth
Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells.
Biomaterials 2005;26(15):2517-25.
2005: David L Allen; Jesse N Weber; Laura K Sycuro; Leslie A Leinwand
Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.
The Journal of biological chemistry 2005;280(17):17126-34.
2005: Erin D Milligan; Stephen J Langer; Evan M Sloane; Lin He; Julie Wieseler Frank; Kevin O'Connor; David Martin; John R Forsayeth; Steven F Maier; Kirk Johnson; Raymond A Chavez; Leslie A Leinwand; Linda R Watkins
Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10.
The European journal of neuroscience 2005;21(8):2136-48.
2005: Peter D Mariner; Stephen W Luckey; Carlin S Long; Carmen C Sucharov; Leslie A Leinwand
Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy.
Biochemical and biophysical research communications 2005;326(1):79-86.
2005: Erin D Milligan; Evan M Sloane; Stephen J Langer; Pedro E Cruz; Marucia Chacur; Leah Spataro; Julie Wieseler Frank; Sayamwong E Hammack; Steven F Maier; Terence R Flotte; John R Forsayeth; Leslie A Leinwand; Raymond A Chavez; Linda R Watkins
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10.
Molecular pain 2005;1():9.
2004: John P Konhilas; Alexander H Maass; Stephen W Luckey; Brian L Stauffer; Eric N Olson; Leslie A Leinwand
Sex modifies exercise and cardiac adaptation in mice.
American journal of physiology. Heart and circulatory physiology 2004;287(6):H2768-76.
2004: Alexander H Maass; Kaori Ikeda; Silke Oberdorf-Maass; Sebastian K G Maier; Leslie A Leinwand
Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T.
Circulation 2004;110(15):2102-9.
2004: Kristyn S Masters; Darshita N Shah; Gennyne Walker; Leslie A Leinwand; Kristi S Anseth
Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials.
Journal of biomedical materials research. Part A 2004;71(1):172-80.
2004: Carmen C Sucharov; Steve M Helmke; Stephen J Langer; M Benjamin Perryman; Michael R Bristow; Leslie A Leinwand
The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression.
Molecular and cellular biology 2004;24(19):8705-15.
2004: Julian E Stelzer; Jitandrakumar R Patel; M Charlotte Olsson; Daniel P Fitzsimons; Leslie A Leinwand; Richard L Moss
Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1756-61.
2004: Ian N Johnston; Erin D Milligan; Julie Wieseler Frank; Matthew G Frank; Varlin Zapata; Jay Campisi; Stephen Langer; David Martin; Paula Green; Monika Fleshner; Leslie A Leinwand; Steven F Maier; Linda R Watkins
A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(33):7353-65.
2004: Gennyne A Walker; Kristyn S Masters; Darshita N Shah; Kristi S Anseth; Leslie A Leinwand
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease.
Circulation research 2004;95(3):253-60.
2004: M Charlotte Olsson; Bradley M Palmer; Brian L Stauffer; Leslie A Leinwand; Russell L Moore
Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy.
Circulation research 2004;94(2):201-7.
2003: Brooke C Harrison; David L Allen; B Girten; Louis S Stodieck; Paul J Kostenuik; Ted A. Bateman; Sean Morony; David L Lacey; Leslie A Leinwand
Skeletal muscle adaptations to microgravity exposure in the mouse.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(6):2462-70.
2003: Nancy A Rice; Leslie A Leinwand
Skeletal myosin heavy chain function in cultured lung myofibroblasts.
The Journal of cell biology 2003;163(1):119-29.
2003: Kurt W Haubold; David L Allen; Yassemi Capetanaki; Leslie A Leinwand
Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(4):1617-22.
2003: Leslie A Leinwand
Hope for a broken heart?
Cell 2003;114(6):658-9.
2003: Carmen C Sucharov; Peter D Mariner; Carlin Long; Michael R Bristow; Leslie A Leinwand
Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter.
The Journal of biological chemistry 2003;278(33):31233-9.
2003: Alexander H Maass; Leslie A Leinwand
Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy.
Trends in cardiovascular medicine 2003;13(6):232-7.
2003: Leslie A Leinwand
Sex is a potent modifier of the cardiovascular system.
The Journal of clinical investigation 2003;112(3):302-7.
2003: Alexander H Maass; Stephen J Langer; Silke Oberdorf-Maass; Sebastian Bauer; Ludwig Neyses; Leslie A Leinwand
Rational promoter selection for gene transfer into cardiac cells.
Journal of molecular and cellular cardiology 2003;35(7):823-31.
2003: Jason Carnes; Marty Jacobson; Leslie A Leinwand; Michael Yarus
Stop codon suppression via inhibition of eRF1 expression.
RNA (New York, N.Y.) 2003;9(6):648-53.
2003: Richard H Weisbart; Fusheng Yang; Grace Chan; Rika Wakelin; Kevin Ferreri; Debra Zack; Brooke Harrison; Leslie A Leinwand; Gregory M. Cole
Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb.
Molecular immunology 2003;39(13):783-9.
2003: Kurt Haubold; Harald Herrmann; Stephen J Langer; Robert M Evans; Leslie A Leinwand; Michael Klymkowsky
Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes.
Cell motility and the cytoskeleton 2003;54(2):105-21.
2003: David T Lucas; Prafulla Aryal; Luke I Szweda; Walter J Koch; Leslie A Leinwand
Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2003;284(2):H575-83.
2003: Massimo Buvoli; Ada Buvoli; Leslie A Leinwand
Suppressor tRNAs: protocols and applications for cardiac gene transfer.
Methods in molecular biology (Clifton, N.J.) 2003;219():115-27.
2002: Henrik H Petersen; Jonathan C Choy; Brian Stauffer; Farzad Moien-Afshari; Christian Aalkjaer; Leslie A Leinwand; Bruce M McManus; Ismail Laher
Coronary artery myogenic response in a genetic model of hypertrophic cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2244-9.
2002: David L Allen; Leslie A Leinwand
Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter.
The Journal of biological chemistry 2002;277(47):45323-30.
2002: Joseph Loscalzo; Robert Balaban; Lance B Becker; Geoffrey S Ginsburg; vladimir hachinski; John E Hall; Donald D Heistad; Leslie A Leinwand; Claude Lenfant; Eduardo Marban; Eric N Olson; Stephen M Schwartz
Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report.
Circulation 2002;106(20):e149-61.
2002: Stephen J Langer; A Paiman Ghafoori; Marshall Byrd; Leslie A Leinwand
A genetic screen identifies novel non-compatible loxP sites.
Nucleic acids research 2002;30(14):3067-77.
2002: Helen-Ann Brown Epstein; Peter B Bitterman; Brooke Mossman; Marvin I Schwarz; Dean Sheppard; Laura A Almasy; Harold A Chapman; Scott L Friedman; Talmadge E King; Leslie A Leinwand; Lance Liotta; George R Martin; David A Schwartz; Gregory Schultz; Carston R Wagner; Robert A Musson
Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group.
American journal of respiratory and critical care medicine 2002;166(2):236-46.
2002: David L Allen; Brooke C Harrison; Leslie A Leinwand
Molecular and genetic approaches to studying exercise performance and adaptation.
Exercise and sport sciences reviews 2002;30(3):99-105.
2002: Imanuel Lerman; Brooke C Harrison; Kalev Freeman; Timothy E Hewett; David L Allen; Jeffrey Robbins; Leslie A Leinwand
Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(6):2245-55.
2002: Massimo Buvoli; Stephen J Langer; S Bialik; Leslie A Leinwand
Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors.
Gene therapy 2002;9(3):227-31.
2002: Alexander H Maass; John P Konhilas; Brian L Stauffer; Leslie A Leinwand
From sarcomeric mutations to heart disease: understanding familial hypertrophic cardiomyopathy.
Cold Spring Harbor symposia on quantitative biology 2002;67():409-15.
2002: Massimo Buvoli; Leslie A Leinwand
Direct gene transfer into mouse heart.
Methods in enzymology 2002;346():134-42.
2002: Brooke C Harrison; M L Bell; David L Allen; William C Byrnes; Leslie A Leinwand
Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(1):313-22.
2001: David L Allen; CA Sartorius; Laura K Sycuro; Leslie A Leinwand
Different pathways regulate expression of the skeletal myosin heavy chain genes.
The Journal of biological chemistry 2001;276(47):43524-33.
2001: K Freeman; K Nakao; Leslie A Leinwand
Low sequence variation in the gene encoding the human beta-myosin heavy chain.
Genomics 2001;76(1-3):73-80.
2001: Alexander H Maass; Leslie A Leinwand
A role for calreticulin in the adult heart?
The Journal of clinical investigation 2001;107(10):1223-5.
2001: David L Allen; Brooke C Harrison; Alexander H Maass; M L Bell; William C Byrnes; Leslie A Leinwand
Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse.
Journal of applied physiology (Bethesda, Md. : 1985) 2001;90(5):1900-8.
2001: K Freeman; I Lerman; E G Kranias; T Bohlmeyer; M R Bristow; R J Lefkowitz; guido iaccarino; Walter J Koch; Leslie A Leinwand
Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy.
The Journal of clinical investigation 2001;107(8):967-74.
2001: Leslie A Leinwand
Calcineurin inhibition and cardiac hypertrophy: a matter of balance.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):2947-9.
2001: M Charlotte Olsson; Bradley M Palmer; Leslie A Leinwand; Russell L Moore
Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy.
American journal of physiology. Heart and circulatory physiology 2001;280(3):H1136-44.
2001: David L Allen; Brooke C Harrison; CA Sartorius; William C Byrnes; Leslie A Leinwand
Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy.
American journal of physiology. Cell physiology 2001;280(3):C637-45.
2001: Murali Chandra; Veronica L M Rundell; Jil C Tardiff; Leslie A Leinwand; Pieter P de Tombe; R John Solaro
Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T.
American journal of physiology. Heart and circulatory physiology 2001;280(2):H705-13.
2001: David L Allen; Leslie A Leinwand
Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.
Developmental biology 2001;229(2):383-95.
2001: K Freeman; C Colon-Rivera; M Charlotte Olsson; Russell L Moore; H D Weinberger; I L Grupp; Karen Lynn Vikstrom; guido iaccarino; Walter J Koch; Leslie A Leinwand
Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H151-9.
2000: J Carnes; Ludmila Frolova; S Zinnen; G Drugeon; M Phillippe; Just Justesen; Anne-Lise Haenni; Leslie A Leinwand; Lev L Kisselev; Michael Yarus
Suppression of eukaryotic translation termination by selected RNAs.
RNA (New York, N.Y.) 2000;6(10):1468-79.
2000: David L Allen; Brooke C Harrison; Leslie A Leinwand
Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes.
Microscopy research and technique 2000;50(6):492-9.
2000: Marco Testa; Pierre-Vladimir Ennezat; Karen Lynn Vikstrom; L Demopoulos; M Gentilucci; Francesco Loperfido; R Fanelli; Richard N Kitsis; Leslie A Leinwand; Thierry H LeJemtel
Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure.
Italian heart journal : official journal of the Italian Federation of Cardiology 2000;1(6):426-30.
2000: Ada Buvoli; Massimo Buvoli; Leslie A Leinwand
Enhanced detection of tRNA isoacceptors by combinatorial oligonucleotide hybridization.
RNA (New York, N.Y.) 2000;6(6):912-8.
2000: Alexander H Maass; Leslie A Leinwand
Animal models of hypertrophic cardiomyopathy.
Current opinion in cardiology 2000;15(3):189-96.
2000: Massimo Buvoli; Ada Buvoli; Leslie A Leinwand
Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes.
Molecular and cellular biology 2000;20(9):3116-24.
2000: S Miyata; Wayne A Minobe; Michael R Bristow; Leslie A Leinwand
Myosin heavy chain isoform expression in the failing and nonfailing human heart.
Circulation research 2000;86(4):386-90.
2000: Jil C Tardiff; TE Hewett; Stephen M Factor; Karen Lynn Vikstrom; J Robbins; Leslie A Leinwand
Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects.
American journal of physiology. Heart and circulatory physiology 2000;278(2):H412-9.
1999: B D Lu; D L Allen; Leslie A Leinwand; G E Lyons
Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.
Developmental biology 1999;216(1):312-26.
1999: Jil C Tardiff; TE Hewett; Bradley M Palmer; C Olsson; Stephen M Factor; Russell L Moore; J Robbins; Leslie A Leinwand
Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.
The Journal of clinical investigation 1999;104(4):469-81.
1999: A Weiss; S Schiaffino; Leslie A Leinwand
Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.
Journal of molecular biology 1999;290(1):61-75.
1999: RE Welikson; Scott H Buck; Jitandrakumar R Patel; Richard L Moss; Karen Lynn Vikstrom; Stephen M Factor; S Miyata; H D Weinberger; Leslie A Leinwand
Cardiac myosin heavy chains lacking the light chain binding domain cause hypertrophic cardiomyopathy in mice.
The American journal of physiology 1999;276(6 Pt 2):H2148-58.
1999: A Weiss; D McDonough; B Wertman; LJ Acakpo-Satchivi; K Montgomery; Raju Kucherlapati; Leslie A Leinwand; K Krauter
Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2958-63.
1998: O Roopnarine; Leslie A Leinwand
Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.
Biophysical journal 1998;75(6):3023-30.
1998: Jil C Tardiff; Stephen M Factor; B D Tompkins; TE Hewett; Bradley M Palmer; Russell L Moore; Steven D Schwartz; J Robbins; Leslie A Leinwand
A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy.
The Journal of clinical investigation 1998;101(12):2800-11.
1998: CA Sartorius; B D Lu; LJ Acakpo-Satchivi; R P Jacobsen; William C Byrnes; Leslie A Leinwand
Myosin heavy chains IIa and IId are functionally distinct in the mouse.
The Journal of cell biology 1998;141(4):943-53.
1998: Karen Lynn Vikstrom; T Bohlmeyer; Stephen M Factor; Leslie A Leinwand
Hypertrophy, pathology, and molecular markers of cardiac pathogenesis.
Circulation research 1998;82(7):773-8.
1997: D C Mayer; Leslie A Leinwand
Sarcomeric gene expression and contractility in myofibroblasts.
The Journal of cell biology 1997;139(6):1477-84.
1997: LJ Acakpo-Satchivi; Winfried Edelmann; CA Sartorius; B D Lu; PA Wahr; simon simon watkins; Joseph M Metzger; Leslie A Leinwand; Raju Kucherlapati
Growth and muscle defects in mice lacking adult myosin heavy chain genes.
The Journal of cell biology 1997;139(5):1219-29.
1997: K Nakao; Wayne A Minobe; Robert Roden; Michael R Bristow; Leslie A Leinwand
Myosin heavy chain gene expression in human heart failure.
The Journal of clinical investigation 1997;100(9):2362-70.
1997: K Li; RE Welikson; Karen Lynn Vikstrom; Leslie A Leinwand
Direct gene transfer into the mouse heart.
Journal of molecular and cellular cardiology 1997;29(5):1499-504.
1997: F M Siri; Linda Jelicks; Leslie A Leinwand; J M Gardin
Gated magnetic resonance imaging of normal and hypertrophied murine hearts.
The American journal of physiology 1997;272(5 Pt 2):H2394-402.
1997: R L Sohn; Karen Lynn Vikstrom; M Strauss; C Cohen; A G Szent-Gyorgyi; Leslie A Leinwand
A 29 residue region of the sarcomeric myosin rod is necessary for filament formation.
Journal of molecular biology 1997;266(2):317-30.
1997: Karen Lynn Vikstrom; S H Seiler; R L Sohn; M Strauss; A Weiss; RE Welikson; Leslie A Leinwand
The vertebrate myosin heavy chain: genetics and assembly properties.
Cell structure and function 1997;22(1):123-9.
1997: A Kass-Eisler; Leslie A Leinwand
DNA- and adenovirus-mediated gene transfer into cardiac muscle.
Methods in cell biology 1997;52():423-37.
1997: K Li; Massimo Buvoli; RE Welikson; Karen Lynn Vikstrom; Leslie A Leinwand
Advances in cardiovascular gene transfer.
Cardiologia (Rome, Italy) 1997;42(1):39-46.
1996: Karen Lynn Vikstrom; Stephen M Factor; Leslie A Leinwand
Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy.
Molecular medicine (Cambridge, Mass.) 1996;2(5):556-67.
1996: J Gall; A Kass-Eisler; Leslie A Leinwand; E Falck-Pedersen
Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes.
Journal of virology 1996;70(4):2116-23.
1996: J G Edwards; Gary E Lyons; Bruce Micales; A Malhotra; Stephen M Factor; Leslie A Leinwand
Cardiomyopathy in transgenic myf5 mice.
Circulation research 1996;78(3):379-87.
1996: A Kass-Eisler; Leslie A Leinwand; J Gall; B Bloom; E Falck-Pedersen
Circumventing the immune response to adenovirus-mediated gene therapy.
Gene therapy 1996;3(2):154-62.
1996: Karen Lynn Vikstrom; Leslie A Leinwand
Contractile protein mutations and heart disease.
Current opinion in cell biology 1996;8(1):97-105.
1996: A Weiss; Leslie A Leinwand
The mammalian myosin heavy chain gene family.
Annual review of cell and developmental biology 1996;12():417-39.
1996: S H Seiler; D A Fischman; Leslie A Leinwand
Modulation of myosin filament organization by C-protein family members.
Molecular biology of the cell 1996;7(1):113-27.
1995: A Kass-Eisler; K Li; Leslie A Leinwand
Prospects for gene therapy with direct injection of polynucleotides.
Annals of the New York Academy of Sciences 1995;772():232-40.
1995: J M Gardin; F M Siri; Richard N Kitsis; J G Edwards; Leslie A Leinwand
Echocardiographic assessment of left ventricular mass and systolic function in mice.
Circulation research 1995;76(5):907-14.
1995: L Liao; R Sindhwani; M Rojkind; Stephen M Factor; Leslie A Leinwand; Betty Diamond
Antibody-mediated autoimmune myocarditis depends on genetically determined target organ sensitivity.
The Journal of experimental medicine 1995;181(3):1123-31.
1995: Karen Lynn Vikstrom; Stephen M Factor; Leslie A Leinwand
A murine model for hypertrophic cardiomyopathy.
Zeitschrift für Kardiologie 1995;84 Suppl 4():49-54.
1994: A Kass-Eisler; E Falck-Pedersen; D H Elfenbein; M Alvira; Peter M Buttrick; Leslie A Leinwand
The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer.
Gene therapy 1994;1(6):395-402.
1994: M L Kaplan; Y Cheslow; Karen Lynn Vikstrom; A Malhotra; David L Geenen; A Nakouzi; Leslie A Leinwand; Peter M Buttrick
Cardiac adaptations to chronic exercise in mice.
The American journal of physiology 1994;267(3 Pt 2):H1167-73.
1994: M Cho; S M Hughes; I Karsch-Mizrachi; M Travis; Leslie A Leinwand; Helen M Blau
Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception.
Journal of cell science 1994;107 ( Pt 9)():2361-71.
1994: R Sindhwani; F Ismail-Beigi; Leslie A Leinwand
Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression.
The Journal of biological chemistry 1994;269(5):3272-6.
1994: H Lee Sweeney; A J Straceski; Leslie A Leinwand; B A Tikunov; L Faust
Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction.
The Journal of biological chemistry 1994;269(3):1603-5.
1994: A J Straceski; A Geisterfer-Lowrance; Christine E Seidman; Jonathan G Seidman; Leslie A Leinwand
Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):589-93.
1994: Peter M Buttrick; M Kaplan; Leslie A Leinwand; J Scheuer
Alterations in gene expression in the rat heart after chronic pathological and physiological loads.
Journal of molecular and cellular cardiology 1994;26(1):61-7.
1994: J M LeBlanc-Straceski; Y Fukui; R L Sohn; J A Spudich; Leslie A Leinwand
Functional analysis of a cardiac myosin rod in Dictyostelium discoideum.
Cell motility and the cytoskeleton 1994;27(4):313-26.
1994: A Weiss; D C Mayer; Leslie A Leinwand
Diversity of myosin-based motility: multiple genes and functions.
Society of General Physiologists series 1994;49():159-71.
1993: A Kass-Eisler; E Falck-Pedersen; M Alvira; J Rivera; Peter M Buttrick; B A Wittenberg; L Cipriani; Leslie A Leinwand
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11498-502.
1993: L Liao; R Sindhwani; Leslie A Leinwand; Betty Diamond; Stephen M Factor
Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes.
The Journal of clinical investigation 1993;92(6):2877-82.
1993: S M Hughes; M Cho; I Karsch-Mizrachi; M Travis; L Silberstein; Leslie A Leinwand; Helen M Blau
Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle.
Developmental biology 1993;158(1):183-99.
1993: Peter M Buttrick; M L Kaplan; Richard N Kitsis; Leslie A Leinwand
Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results.
Circulation research 1993;72(6):1211-7.
1993: Karen Lynn Vikstrom; A S Rovner; C G Saez; M Bravo-Zehnder; A J Straceski; Leslie A Leinwand
Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains.
Cell motility and the cytoskeleton 1993;26(3):192-204.
1992: S J Yoon; S H Seiler; Raju Kucherlapati; Leslie A Leinwand
Organization of the human skeletal myosin heavy chain gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):12078-82.
1992: R Kraft; L Kadyk; Leslie A Leinwand
Sequence organization of variant mouse 4.5 S RNA genes and pseudogenes.
Genomics 1992;12(3):555-66.
1992: R Feghali; I Karsch-Mizrachi; Leslie A Leinwand; D S Kohtz
Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture.
Gene expression 1992;2(1):49-58.
1992: Richard N Kitsis; Leslie A Leinwand
Discordance between gene regulation in vitro and in vivo.
Gene expression 1992;2(4):313-8.
1992: Peter M Buttrick; A Kass; Richard N Kitsis; M L Kaplan; Leslie A Leinwand
Behavior of genes directly injected into the rat heart in vivo.
Circulation research 1992;70(1):193-8.
1991: Leslie A Leinwand; J M Leiden
Gene transfer into cardiac myocytes in vivo.
Trends in cardiovascular medicine 1991;1(7):271-6.
1991: Richard N Kitsis; Peter M Buttrick; Elizabeth McNally; M L Kaplan; Leslie A Leinwand
Hormonal modulation of a gene injected into rat heart in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(10):4138-42.
1991: Elizabeth McNally; M M Bravo-Zehnder; Leslie A Leinwand
Identification of sequences necessary for the association of cardiac myosin subunits.
The Journal of cell biology 1991;113(3):585-90.
1991: Glenn I Fishman; A P Moreno; david spray; Leslie A Leinwand
Functional analysis of human cardiac gap junction channel mutants.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3525-9.
1991: Glenn I Fishman; R L Eddy; T B Shows; L Rosenthal; Leslie A Leinwand
The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures.
Genomics 1991;10(1):250-6.
1991: Peter M Buttrick; A Malhotra; Stephen M Factor; D Greenen; Leslie A Leinwand; J Scheuer
Effect of aging and hypertension on myosin biochemistry and gene expression in the rat heart.
Circulation research 1991;68(3):645-52.
1991: Glenn I Fishman; Elliot L Hertzberg; david spray; Leslie A Leinwand
Expression of connexin43 in the developing rat heart.
Circulation research 1991;68(3):782-7.
1991: S Frankel; R Sohn; Leslie A Leinwand
The use of sarkosyl in generating soluble protein after bacterial expression.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1192-6.
1991: E McNally; R Sohn; S Frankel; Leslie A Leinwand
Expression of myosin and actin in Escherichia coli.
Methods in enzymology 1991;196():368-89.
1990: E B Goodwin; Leslie A Leinwand; Andrew G Szent-Györgyi
Regulation of scallop myosin by mutant regulatory light chains.
Journal of molecular biology 1990;216(1):85-93.
1990: S Frankel; John Condeelis; Leslie A Leinwand
Expression of actin in Escherichia coli. Aggregation, solubilization, and functional analysis.
The Journal of biological chemistry 1990;265(29):17980-7.
1990: Glenn I Fishman; david spray; Leslie A Leinwand
Molecular characterization and functional expression of the human cardiac gap junction channel.
The Journal of cell biology 1990;111(2):589-98.
1990: I Karsch-Mizrachi; R Feghali; T B Shows; Leslie A Leinwand
Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA.
Gene 1990;89(2):289-94.
1990: A S Rovner; Elizabeth McNally; Leslie A Leinwand
Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension.
Nucleic acids research 1990;18(6):1581-6.
1990: C G Saez; J C Myers; T B Shows; Leslie A Leinwand
Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):1164-8.
1989: Elizabeth McNally; R Kraft; M Bravo-Zehnder; Doris Taylor; Leslie A Leinwand
Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences.
Journal of molecular biology 1989;210(3):665-71.
1989: R Kraft; M Bravo-Zehnder; Doris Taylor; Leslie A Leinwand
Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain.
Nucleic acids research 1989;17(18):7529-30.
1989: Elizabeth McNally; K M Gianola; Leslie A Leinwand
Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain.
Nucleic acids research 1989;17(18):7527-8.
1989: I Karsch-Mizrachi; M Travis; H Blau; Leslie A Leinwand
Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene.
Nucleic acids research 1989;17(15):6167-79.
1989: R Feghali; Leslie A Leinwand
Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain.
The Journal of cell biology 1989;108(5):1791-7.
1989: Elizabeth McNally; Peter M Buttrick; Leslie A Leinwand
Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension.
Nucleic acids research 1989;17(7):2753-67.
1989: Leslie A Leinwand; R Sohn; S A Frankel; E B Goodwin; Elizabeth McNally
Bacterial expression of eukaryotic contractile proteins.
Cell motility and the cytoskeleton 1989;14(1):3-11.
1988: Elizabeth McNally; E B Goodwin; J A Spudich; Leslie A Leinwand
Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7270-3.
1988: D L Heller; K M Gianola; Leslie A Leinwand
A highly conserved mouse gene with a propensity to form pseudogenes in mammals.
Molecular and cellular biology 1988;8(7):2797-803.
1988: R Kraft; Jil C Tardiff; K S Krauter; Leslie A Leinwand
Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase.
BioTechniques 1988;6(6):544-6, 549.
1987: R Kraft; Leslie A Leinwand
Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium.
Nucleic acids research 1987;15(20):8568.
1987: E B Goodwin; A G Szent-Gyorgyi; Leslie A Leinwand
Cloning and characterization of the scallop essential and regulatory myosin light chain cDNAs.
The Journal of biological chemistry 1987;262(23):11052-6.
1987: L J Saez; K M Gianola; Elizabeth McNally; R Feghali; R Eddy; T B Shows; Leslie A Leinwand
Human cardiac myosin heavy chain genes and their linkage in the genome.
Nucleic acids research 1987;15(13):5443-59.
1986: L Saez; Leslie A Leinwand
Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle.
Nucleic acids research 1986;14(7):2951-69.
1986: C E Schwartz; E McNally; Leslie A Leinwand; M H Skolnick
A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13.
Cytogenetics and cell genetics 1986;43(1-2):117-20.
1983: Leslie A Leinwand; L Saez; E McNally; B Nadal-Ginard
Isolation and characterization of human myosin heavy chain genes.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(12):3716-20.
1982: K Krauter; Leslie A Leinwand; P D'Eustachio; F Ruddle; J E Darnell
Structural genes of the mouse major urinary protein are on chromosome 4.
The Journal of cell biology 1982;94(2):414-7.