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John Lemasters

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Anatomy

Procedures

Disorders

Reperfusion Injury

Physiology

Chemicals & Drugs

Phenomena

Permeability

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Hydrogen-Ion Concentration

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Co-Publications
Name
79
Thurman, Ronald
51
Herman, Brian
33
Nieminen, Anna-Liisa
31
Zhong, Zhi
23
Qian, Ting
21
Brenner, David
15
Mason, Ronald
14
Bunzendahl, Hartwig
14
Connor, Henry
12
Cascio, Wayne
9
Kim, Jae-Sung
9
He, Lihua
9
Jaeschke, Hartmut
8
Egan, Thomas
7
Bradham, Cynthia

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Publications

TOP 3
Lemasters John J; Theruvath Tom P; Zhong Zhi; Nieminen Anna-Liisa
Mitochondrial calcium and the permeability transition in cell death.
Holmuhamedov Ekhson; Lemasters John J
Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes.
Rehman Hasibur; Ramshesh Venkat K; Theruvath Tom P; Kim Insil; Currin Robert T; Giri Shailendra; Lemasters John J; Zhong Zhi
NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice.

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All Publications

2009: Lemasters John J; Theruvath Tom P; Zhong Zhi; Nieminen Anna-Liisa
Mitochondrial calcium and the permeability transition in cell death.
Biochimica et biophysica acta 2009;1787(11):1395-401.
2009: Holmuhamedov Ekhson; Lemasters John J
Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes.
Archives of biochemistry and biophysics 2009;481(2):226-33.
2008: Rehman Hasibur; Ramshesh Venkat K; Theruvath Tom P; Kim Insil; Currin Robert T; Giri Shailendra; Lemasters John J; Zhong Zhi
NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice.
The Journal of pharmacology and experimental therapeutics 2008;327(3):699-706.
2008: Ramshesh Venkat K; Lemasters John J
Pinhole shifting lifetime imaging microscopy.
Journal of biomedical optics 2008;13(6):064001.
2008: Theruvath Tom P; Lemasters John J
Cyclosporine in acute myocardial infarction.
The New England journal of medicine 2008;359(21):2286; author reply 2288-9.
2008: Brookes Paul S; Parker Nadeene; Buckingham Julie A; Vidal-Puig Antonio; Halestrap Andrew P; Gunter Thomas E; Nicholls David G; Bernardi Paolo; Lemasters John J; Brand Martin D
UCPs--unlikely calcium porters.
Nature cell biology 2008;10(11):1235-7; author reply 1237-40.
2008: Uchiyama Akira; Kim Jae-Sung; Kon Kazuyoshi; Jaeschke Hartmut; Ikejima Kenichi; Watanabe Sumio; Lemasters John J
Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury.
Hepatology (Baltimore, Md.) 2008;48(5):1644-54.
2008: Zhong Zhi; Ramshesh Venkat K; Rehman Hasibur; Currin Robert T; Sridharan Vijayalakshmi; Theruvath Tom P; Kim Insil; Wright Gary L; Lemasters John J
Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(4):G823-32.
2008: Theruvath T P; Czerny C; Ramshesh V K; Zhong Z; Chavin K D; Lemasters J J
C-Jun N-terminal kinase 2 promotes graft injury via the mitochondrial permeability transition after mouse liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(9):1819-28.
2008: Theruvath Tom P; Snoddy Mark C; Zhong Zhi; Lemasters John J
Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2.
Transplantation 2008;85(10):1500-4.
2008: Rehman Hasibur; Connor Henry D; Ramshesh Venkat K; Theruvath Tom P; Mason Ronald P; Wright Gary L; Lemasters John J; Zhong Zhi
Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts.
Transplantation 2008;85(9):1322-31.
2008: Theruvath Tom P; Zhong Zhi; Pediaditakis Peter; Ramshesh Venkat K; Currin Robert T; Tikunov Andrey; Holmuhamedov Ekhson; Lemasters John J
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition.
Hepatology (Baltimore, Md.) 2008;47(1):236-46.
2008: Bajt Mary Lynn; Farhood Anwar; Lemasters John J; Jaeschke Hartmut
Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity.
The Journal of pharmacology and experimental therapeutics 2008;324(1):8-14.
2007: Black Dalliah; Lyman Suzanne; Qian Ting; Lemasters John J; Rippe Richard A; Nitta Takashi; Kim Jae-Sung; Behrns Kevin E
Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species.
Biochimie 2007;89(12):1464-73.
2007: Takei Yoshiyuki; Maruyama Atsushi; Ikejima Kenichi; Enomoto Nobuyuki; Yamashina Shunhei; Lemasters John J; Sato Nobuhiro
Genetic manipulation of sinusoidal endothelial cells.
Journal of gastroenterology and hepatology 2007;22 Suppl 1():S68-72.
2007: Kon Kazuyoshi; Ikejima Kenichi; Okumura Kyoko; Aoyama Tomonori; Arai Kumiko; Takei Yoshiyuki; Lemasters John J; Sato Nobuhiro
Role of apoptosis in acetaminophen hepatotoxicity.
Journal of gastroenterology and hepatology 2007;22 Suppl 1():S49-52.
2007: Lemasters John J
Modulation of mitochondrial membrane permeability in pathogenesis, autophagy and control of metabolism.
Journal of gastroenterology and hepatology 2007;22 Suppl 1():S31-7.
2007: Kim Insil; Rodriguez-Enriquez Sara; Lemasters John J
Selective degradation of mitochondria by mitophagy.
Archives of biochemistry and biophysics 2007;462(2):245-53.
2007: Zhong Z; Theruvath T P; Currin R T; Waldmeier P C; Lemasters J J
NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(5):1103-11.
2007: Conzelmann Lars O; Hines Ian N; Kremer Michael; Perry Ashley W; Lemasters John J; Wheeler Michael D
Extrahepatic cells contribute to the progenitor/stem cell response following reduced-size liver transplantation in mice.
Experimental biology and medicine (Maywood, N.J.) 2007;232(4):571-80.
2007: Hammond Linda E; Albright Craig D; He Lihua; Rusyn Ivan; Watkins Steven M; Doughman Scott D; Lemasters John J; Coleman Rosalind A
Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice.
Experimental and molecular pathology 2007;82(2):210-9.
2007: Le Son B; Hailer M Katie; Buhrow Sarah; Wang Qi; Flatten Karen; Pediaditakis Peter; Bible Keith C; Lewis Lionel D; Sausville Edward A; Pang Yuan-Ping; Ames Matthew M; Lemasters John J; Holmuhamedov Ekhson L; Kaufmann Scott H
Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity.
The Journal of biological chemistry 2007;282(12):8860-72.
2007: Lemasters John J; Ramshesh Venkat K
Imaging of mitochondrial polarization and depolarization with cationic fluorophores.
Methods in cell biology 2007;80():283-95.
2006: Theruvath T P; Zhong Z; Currin R T; Ramshesh V K; Lemasters J J
Endothelial nitric oxide synthase protects transplanted mouse livers against storage/reperfusion injury: Role of vasodilatory and innate immunity pathways.
Transplantation proceedings 2006;38(10):3351-7.
2006: Raval Jay; Lyman Suzanne; Nitta Takashi; Mohuczy Dagmara; Lemasters John J; Kim Jae-Sung; Behrns Kevin E
Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes.
Free radical biology & medicine 2006;41(11):1645-54.
2006: Kim Jae-Sung; Lemasters John J
Opioid receptor-independent protection of ischemic rat hepatocytes by morphine.
Biochemical and biophysical research communications 2006;351(4):958-64.
2006: Zhong Zhi; Connor Henry D; Li Xiangli; Mason Ronald P; Forman Donald T; Lemasters John J; Thurman Ronald G
Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.
The Journal of pharmacy and pharmacology 2006;58(11):1533-43.
2006: Conzelmann Lars O; Lehnert Mark; Kremer Michael; Zhong Zhi; Wheeler Michael D; Lemasters John J
Graft tumor necrosis factor receptor-1 protects after mouse liver transplantation whereas host tumor necrosis factor receptor-1 promotes injury.
Transplantation 2006;82(9):1214-20.
2006: Bajt Mary Lynn; Cover Cathleen; Lemasters John J; Jaeschke Hartmut
Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(1):217-25.
2006: Lehnert Mark; Uehara Tetsuya; Bradford Blair U; Lind Henrik; Zhong Zhi; Brenner David A; Marzi Ingo; Lemasters John J
Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(3):G456-63.
2006: Zhong Zhi; Schwabe Robert F; Kai Yoichiro; He Lihua; Yang Liu; Bunzendahl Hartwig; Brenner David A; Lemasters John J
Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply.
Transplantation 2006;82(2):241-50.
2006: Kim Jae-Sung; Jin Yingai; Lemasters John J
Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion.
American journal of physiology. Heart and circulatory physiology 2006;290(5):H2024-34.
2006: Vairetti Mariapia; Richelmi Plinio; Bertè Francantonio; Currin Robert T; Lemasters John J; Imberti Roberto
Role of pH in protection by low sodium against hypoxic injury in isolated perfused rat livers.
Journal of hepatology 2006;44(5):894-901.
2006: Lehmann Thorsten G; Luedde Tom; Schwabe Robert F; Bunzendahl Hartwig; Samulski R Jude; Lemasters John J; Brenner David A
Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(4):550-9.
2006: Chimalakonda Anjaneya P; Montgomery Donald L; Weidanz Jon A; Shaik Imam H; Nguyen Justin H; Lemasters John J; Kobayashi Eiji; Mehvar Reza
Attenuation of acute rejection in a rat liver transplantation model by a liver-targeted dextran prodrug of methylprednisolone.
Transplantation 2006;81(5):678-85.
2006: Malhi Harmeet; Gores Gregory J; Lemasters John J
Apoptosis and necrosis in the liver: a tale of two deaths?
Hepatology (Baltimore, Md.) 2006;43(2 Suppl 1):S31-44.
2006: Lemasters John J; Holmuhamedov Ekhson
Voltage-dependent anion channel (VDAC) as mitochondrial governator--thinking outside the box.
Biochimica et biophysica acta 2006;1762(2):181-90.
2006: Rodriguez-Enriquez Sara; Kim Insil; Currin Robert T; Lemasters John J
Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes.
Autophagy 2006;2(1):39-46.
2005: Cover Cathleen; Mansouri Abdellah; Knight Tamara R; Bajt Mary Lynn; Lemasters John J; Pessayre Dominique; Jaeschke Hartmut
Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity.
The Journal of pharmacology and experimental therapeutics 2005;315(2):879-87.
2005: Bustamante Ernesto; Pediaditakis Peter; He Lihua; Lemasters John J
Isolated mouse liver mitochondria are devoid of glucokinase.
Biochemical and biophysical research communications 2005;334(3):907-10.
2005: He Lihua; Lemasters John J
Dephosphorylation of the Rieske iron-sulfur protein after induction of the mitochondrial permeability transition.
Biochemical and biophysical research communications 2005;334(3):829-37.
2005: Zhong Zhi; Connor Henry D; Froh Mattias; Bunzendahl Hartwig; Lind Henrik; Lehnert Mark; Mason Ronald P; Thurman Ronald G; Lemasters John J
Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols.
Gastroenterology 2005;129(2):652-64.
2005: Lemasters John J
Dying a thousand deaths: redundant pathways from different organelles to apoptosis and necrosis.
Gastroenterology 2005;129(1):351-60.
2005: Lemasters John J
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging.
Rejuvenation research 2005;8(1):3-5.
2004: Kim Jae-Sung; Ohshima Shigetoshi; Pediaditakis Peter; Lemasters John J
Nitric oxide: a signaling molecule against mitochondrial permeability transition- and pH-dependent cell death after reperfusion.
Free radical biology & medicine 2004;37(12):1943-50.
2004: Rodriguez-Enriquez Sara; He Lihua; Lemasters John J
Role of mitochondrial permeability transition pores in mitochondrial autophagy.
The international journal of biochemistry & cell biology 2004;36(12):2463-72.
2004: Kon Kazuyoshi; Kim Jae-Sung; Jaeschke Hartmut; Lemasters John J
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes.
Hepatology (Baltimore, Md.) 2004;40(5):1170-9.
2004: Zhong Zhi; Lemasters John J
Role of free radicals in failure of fatty liver grafts caused by ethanol.
Alcohol (Fayetteville, N.Y.) 2004;34(1):49-58.
2004: Uehara Tetsuya; Xi Peng Xing; Bennett Brydon; Satoh Yoshi; Friedman Glenn; Currin Robert; Brenner David A; Lemasters John
c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation.
Transplantation 2004;78(3):324-32.
2004: Bajt Mary Lynn; Knight Tamara R; Lemasters John J; Jaeschke Hartmut
Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(2):343-9.
2004: Kim Jae-Sung; Ohshima Shigetoshi; Pediaditakis Peter; Lemasters John J
Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition.
Hepatology (Baltimore, Md.) 2004;39(6):1533-43.
2004: Black Dalliah; Bird Mark A; Samson Charles M; Lyman Suzanne; Lange Patty A; Schrum Laura W; Qian Ting; Lemasters J J; Brenner David A; Rippe Richard A; Behrns Kevin E
Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism.
Journal of hepatology 2004;40(6):942-51.
2004: Lemasters John J
Whither our libraries?
Gastroenterology 2004;126(5):1234.
2004: Zhong Zhi; Connor Henry D; Froh Mattias; Lind Henrik; Bunzendahl Hartwig; Mason Ronald P; Thurman Ronald G; Lemasters John J
Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats.
Free radical biology & medicine 2004;36(10):1248-58.
2004: Lemasters John J
Rusty notions of cell injury.
Journal of hepatology 2004;40(4):696-8.
2004: Takei Yoshiyuki; Maruyama Atsushi; Ferdous Anwarul; Nishimura Yoshiya; Kawano Sunao; Ikejima Kenichi; Okumura Shigetoshi; Asayama Shoichiro; Nogawa Masayuki; Hashimoto Masao; Makino Yoko; Kinoshita Masahiko; Watanabe Sumio; Akaike Toshihiro; Lemasters John J; Sato Nobuhiro
Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):699-701.
2004: Schwabe Robert F; Uchinami Hiroshi; Qian Ting; Bennett Brydon L; Lemasters John J; Brenner David A
Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(6):720-2.
2004: Bataller Ramó; Paik Yong-Han; Lindquist Jeffrey N; Lemasters John J; Brenner David A
Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells.
Gastroenterology 2004;126(2):529-40.
2004: Elmore Steven P; Nishimura Yoshiya; Qian Ting; Herman Brian; Lemasters John J
Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer.
Archives of biochemistry and biophysics 2004;422(2):145-52.
2003: Bataller Ramon; Schwabe Robert F; Choi Youkyung H; Yang Liu; Paik Yong Han; Lindquist Jeffrey; Qian Ting; Schoonhoven Robert; Hagedorn Curt H; Lemasters John J; Brenner David A
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis.
The Journal of clinical investigation 2003;112(9):1383-94.
2003: Zhong Zhi; Froh Matthias; Lehnert Mark; Schoonhoven Robert; Yang Liu; Lind Henrik; Lemasters John J; Thurman Ronald G
Polyphenols from Camellia sinenesis attenuate experimental cholestasis-induced liver fibrosis in rats.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(5):G1004-13.
2003: Jaeschke Hartmut; Lemasters John J
Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury.
Gastroenterology 2003;125(4):1246-57.
2003: Kim J S; He L; Qian T; Lemasters J J
Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes.
Current molecular medicine 2003;3(6):527-35.
2003: Zhao Yongge; Ding Wen-Xing; Qian Ting; Watkins Simon; Lemasters John J; Yin Xiao-Ming
Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement.
Gastroenterology 2003;125(3):854-67.
2003: Conzelmann Lars O; Zhong Zhi; Bunzendahl Hartwig; Wheeler Michael D; Lemasters John J
Reduced-size liver transplantation in the mouse.
Transplantation 2003;76(3):496-501.
2003: Waldmeier Peter C; Zimmermann Kaspar; Qian Ting; Tintelnot-Blomley Marina; Lemasters John J
Cyclophilin D as a drug target.
Current medicinal chemistry 2003;10(16):1485-506.
2003: Lehmann Thorsten G; Wheeler Michael D; Froh Matthias; Schwabe Robert F; Bunzendahl Hartwig; Samulski R Jude; Lemasters John J; Brenner David A; Thurman Ronald G
Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat.
Transplantation 2003;76(1):28-37.
2003: Kweon Young-Oh; Paik Yong-Han; Schnabl Bernd; Qian Ting; Lemasters John J; Brenner David A
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells.
Journal of hepatology 2003;39(1):38-46.
2003: Kim Jae-Sung; He Lihua; Lemasters John J
Mitochondrial permeability transition: a common pathway to necrosis and apoptosis.
Biochemical and biophysical research communications 2003;304(3):463-70.
2003: Oh Ki-Wan; Qian Ting; Brenner David A; Lemasters John J
Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(1):44-52.
2003: He Lihua; Lemasters John J
Heat shock suppresses the permeability transition in rat liver mitochondria.
The Journal of biological chemistry 2003;278(19):16755-60.
2003: Lehnert Mark; Arteel Gavin E; Smutney Olivia M; Conzelmann Lars O; Zhong Zhi; Thurman Ronald G; Lemasters John J
Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide.
Shock (Augusta, Ga.) 2003;19(4):345-51.
2003: Zhong Zhi; Wheeler Micheal D; Li Xiangli; Froh Matthias; Schemmer Peter; Yin Ming; Bunzendaul Hartwig; Bradford Blair; Lemasters John J
L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent.
Current opinion in clinical nutrition and metabolic care 2003;6(2):229-40.
2003: Kim Jae-Sung; Qian Ting; Lemasters John J
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes.
Gastroenterology 2003;124(2):494-503.
2003: Lemasters John J
Impact factors--a good thing?
Gastroenterology 2003;124(2):286.
2002: Kim Young-Soo; Schwabe Robert F; Qian Ting; Lemasters John J; Brenner David A
TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
Hepatology (Baltimore, Md.) 2002;36(6):1498-508.
2002: Lemasters John J; Qian Ting; He Lihua; Kim Jae-Sung; Elmore Steven P; Cascio Wayne E; Brenner David A
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy.
Antioxidants & redox signaling 2002;4(5):769-81.
2002: Zhong Zhi; Froh Matthias; Connor Henry D; Li Xiangli; Conzelmann Lars O; Mason Ronald P; Lemasters John J; Thurman Ronald G
Prevention of hepatic ischemia-reperfusion injury by green tea extract.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G957-64.
2002: Waldmeier Peter C; Feldtrauer Jean-Jacques; Qian Ting; Lemasters John J
Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.
Molecular pharmacology 2002;62(1):22-9.
2002: Yin Ming; Currin Robert T; Peng Xing-Xi; Mekeel Harold E; Schoonhoven Robert; Lemasters John J
Carolina rinse solution minimizes kidney injury and improves graft function and survival after prolonged cold ischemia.
Transplantation 2002;73(9):1410-20.
2002: Yin Ming; Currin Robert T; Peng Xing-Xi; Mekeel Harold E; Schoonhoven Robert; Lemasters John J
Different patterns of renal cell killing after warm and cold ischemia.
Renal failure 2002;24(2):147-63.
2002: He Lihua; Lemasters John J
Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?
FEBS letters 2002;512(1-3):1-7.
2002: Jaeschke Hartmut; Gores Gregory J; Cederbaum Arthur I; Hinson Jack A; Pessayre Dominique; Lemasters John J
Mechanisms of hepatotoxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2002;65(2):166-76.
2001: Cascio W E; Yang H; Johnson T A; Muller-Borer B J; Lemasters J J
Electrical properties and conduction in reperfused papillary muscle.
Circulation research 2001;89(9):807-14.
2001: Elmore S P; Qian T; Grissom S F; Lemasters J J
The mitochondrial permeability transition initiates autophagy in rat hepatocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(12):2286-7.
2001: Lemasters J J
Cytochrome c: which way out?
Hepatology (Baltimore, Md.) 2001;34(3):605-7.
2001: Nishimura Y; Lemasters J J
Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia.
Cell death and differentiation 2001;8(8):850-8.
2001: Blattner J R; He L; Lemasters J J
Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader.
Analytical biochemistry 2001;295(2):220-6.
2001: Schemmer P; Enomoto N; Bradford B U; Bunzendahl H; Raleigh J A; Lemasters J J; Thurman R G
Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(6):G1076-82.
2001: Hunt J P; Hunter C T; Brownstein M R; Ku J; Roberts L; Currin R T; Lemasters J J; Baker C C
Alteration in Kupffer cell function after mild hemorrhagic shock.
Shock (Augusta, Ga.) 2001;15(5):403-7.
2001: Arai M; Thurman R G; Lemasters J J
Ischemic preconditioning of rat livers against cold storage-reperfusion injury: role of nonparenchymal cells and the phenomenon of heterologous preconditioning.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2001;7(4):292-9.
2001: Hatano E; Bennett B L; Manning A M; Qian T; Lemasters J J; Brenner D A
NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis.
Gastroenterology 2001;120(5):1251-62.
2000: Huynh T; Lemasters J J; Bracey L W; Baker C C
Proinflammatory kupffer cell alterations after femur fracture trauma and sepsis in rats.
Shock (Augusta, Ga.) 2000;14(5):555-60.
2000: Rudolph J G; Lemasters J J; Crews F T
Effects of NMDA and ferrous sulfate on oxidation and cell death in primary neuronal cultures.
Neurochemistry international 2000;37(5-6):497-507.
2000: Nicholls D; Bernardi P; Brand M; Halestrap A; Lemasters J; Reynolds I
Apoptosis and the laws of thermodynamics.
Nature cell biology 2000;2(10):E172-3.
2000: Oh K W; Currin R T; Lemasters J J
Kupffer cells mediate increased anoxic hepatocellular killing from hyperosmolarity by an oxygen- and prostaglandin-independent mechanism.
Toxicology letters 2000;117(1-2):95-100.
2000: Arai M; Thurman R G; Lemasters J J
Contribution of adenosine A(2) receptors and cyclic adenosine monophosphate to protective ischemic preconditioning of sinusoidal endothelial cells against Storage/Reperfusion injury in rat livers.
Hepatology (Baltimore, Md.) 2000;32(2):297-302.
2000: Trollinger D R; Cascio W E; Lemasters J J
Mitochondrial calcium transients in adult rabbit cardiac myocytes: inhibition by ruthenium red and artifacts caused by lysosomal loading of Ca(2+)-indicating fluorophores.
Biophysical journal 2000;79(1):39-50.
2000: El Bawab S; Roddy P; Qian T; Bielawska A; Lemasters J J; Hannun Y A
Molecular cloning and characterization of a human mitochondrial ceramidase.
The Journal of biological chemistry 2000;275(28):21508-13.
2000: Hatano E; Bradham C A; Stark A; Iimuro Y; Lemasters J J; Brenner D A
The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes.
The Journal of biological chemistry 2000;275(16):11814-23.
2000: Schemmer P; Bradford B U; Bunzendahl H; Lemasters J J; Thurman R G
Gentle in situ liver manipulation during organ harvest increases oxygen consumption in liver.
Transplantation proceedings 2000;32(1):112.
1999: Lemasters J J
The mitochondrial permeability transition and the calcium, oxygen and pH paradoxes: one paradox after another.
Cardiovascular research 1999;44(3):470-3.
1999: Lemasters J J; Nieminen A L
Negative contrast imaging of mitochondria by confocal microscopy.
Biophysical journal 1999;77(3):1747-50.
1999: Zhang Y; Lemasters J; Herman B
Secretory group IIA phospholipase A(2) generates anti-apoptotic survival signals in kidney fibroblasts.
The Journal of biological chemistry 1999;274(39):27726-33.
1999: Lemasters J J; Qian T; Bradham C A; Brenner D A; Cascio W E; Trost L C; Nishimura Y; Nieminen A L; Herman B
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death.
Journal of bioenergetics and biomembranes 1999;31(4):305-19.
1999: Arai M; Peng X X; Currin R T; Thurman R G; Lemasters J J
Protection of sinusoidal endothelial cells against storage/reperfusion injury by prostaglandin E2 derived from Kupffer cells.
Transplantation 1999;68(3):440-5.
1999: Zhong Z; Arteel G E; Connor H D; Schemmer P; Chou S C; Raleigh J A; Mason R P; Lemasters J J; Thurman R G
Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers.
The Journal of pharmacology and experimental therapeutics 1999;290(2):611-20.
1999: Liu X; LeCluyse E L; Brouwer K R; Gan L S; Lemasters J J; Stieger B; Meier P J; Brouwer K L
Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration.
The American journal of physiology 1999;277(1 Pt 1):G12-21.
1999: Byrne A M; Lemasters J J; Nieminen A L
Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes.
Hepatology (Baltimore, Md.) 1999;29(5):1523-31.
1999: Schemmer P; Bradford B U; Rose M L; Bunzendahl H; Raleigh J A; Lemasters J J; Thurman R G
Intravenous glycine improves survival in rat liver transplantation.
The American journal of physiology 1999;276(4 Pt 1):G924-32.
1999: Takei Y; Maruyama A; Kawano S; Nishimura Y; Asayama S; Nogawa M; Ikejima K; Hori M; Akaike T; Lemasters J J; Watanabe S; Sato N
Targeted gene transfer to sinusoidal endothelial cells and expression in vivo.
Transplantation proceedings 1999;31(1-2):790-1.
1999: Schemmer P; Bunzendahl H; Lemasters J J; Thurman R G
Selective hepatic denervation prior to organ harvest improves survival after liver transplantation.
Transplantation proceedings 1999;31(1-2):537.
1999: Arai M; Thurman R G; Lemasters J J
Involvement of Kupffer cells and sinusoidal endothelial cells in ischemic preconditioning to rat livers stored for transplantation.
Transplantation proceedings 1999;31(1-2):425-7.
1999: Qian T; Herman B; Lemasters J J
The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.
Toxicology and applied pharmacology 1999;154(2):117-25.
1999: Lemasters J J
V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis.
The American journal of physiology 1999;276(1 Pt 1):G1-6.
1999: Lemasters J J; Trollinger D R; Qian T; Cascio W E; Ohata H
Confocal imaging of Ca2+, pH, electrical potential, and membrane permeability in single living cells.
Methods in enzymology 1999;302():341-58.
1999: Lemasters J J; Qian T; Trost L C; Herman B; Cascio W E; Bradham C A; Brenner D A; Nieminen A L
Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death.
Biochemical Society symposium 1999;66():205-22.
1999: Schemmer P; Schoonhoven R; Swenberg J A; Bunzendahl H; Raleigh J A; Lemasters J J; Thurman R G
Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(5):351-9.
1999: v Frankenberg M; Stachlewitz R F; Forman D T; Frey W; Bunzendahl H; Lemasters J J; Thurman R G
Amino acids in rinse effluents as a predictor of graft function after transplantation of fatty livers in rats.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(3):168-75.
1999: Lichtman S N; Lemasters J J
Role of cytokines and cytokine-producing cells in reperfusion injury to the liver.
Seminars in liver disease 1999;19(2):171-87.
1998: Rudolph J G; Lemasters J J; Crews F T
Effects of chronic ethanol exposure on oxidation and NMDA-stimulated neuronal death in primary cortical neuronal cultures.
Alcoholism, clinical and experimental research 1998;22(9):2080-5.
1998: Zhong Z; Connor H D; Mason R P; Lemasters J J; Thurman R G
Ethanol, not fat accumulation per se, increases free radical production in a low-flow, reflow liver perfusion model.
Transplantation 1998;66(11):1431-8.
1998: Muller-Borer B J; Yang H; Marzouk S A; Lemasters J J; Cascio W E
pHi and pHo at different depths in perfused myocardium measured by confocal fluorescence microscopy.
The American journal of physiology 1998;275(6 Pt 2):H1937-47.
1998: Bradham C A; Qian T; Streetz K; Trautwein C; Brenner D A; Lemasters J J
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release.
Molecular and cellular biology 1998;18(11):6353-64.
1998: Lemasters J J
The mitochondrial permeability transition: from biochemical curiosity to pathophysiological mechanism.
Gastroenterology 1998;115(3):783-6.
1998: Lichtman S N; Wang J; Lemasters J J
Lipopolysaccharide-stimulated TNF-alpha release from cultured rat Kupffer cells: sequence of intracellular signaling pathways.
Journal of leukocyte biology 1998;64(3):368-72.
1998: Lemasters J J; Nieminen A L; Qian T; Trost L C; Elmore S P; Nishimura Y; Crowe R A; Cascio W E; Bradham C A; Brenner D A; Herman B
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.
Biochimica et biophysica acta 1998;1366(1-2):177-96.
1998: Lichtman S N; Wang J; Lemasters J J
LPS receptor CD14 participates in release of TNF-alpha in RAW 264.7 and peritoneal cells but not in kupffer cells.
The American journal of physiology 1998;275(1 Pt 1):G39-46.
1998: Hyatt C J; Lemasters J J; Muller-Borer B J; Johnson T A; Cascio W E
A superfusion system to study border zones in confluent cultures of neonatal rat heart cells.
The American journal of physiology 1998;274(6 Pt 2):H2001-8.
1998: Ohata H; Chacon E; Tesfai S A; Harper I S; Herman B; Lemasters J J
Mitochondrial Ca2+ transients in cardiac myocytes during the excitation-contraction cycle: effects of pacing and hormonal stimulation.
Journal of bioenergetics and biomembranes 1998;30(3):207-22.
1998: Nishimura Y; Romer L H; Lemasters J J
Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: the pH paradox and cytoprotection by glucose, acidotic pH, and glycine.
Hepatology (Baltimore, Md.) 1998;27(4):1039-49.
1998: Thurman R G; Schemmer P; Zhong Z; Bunzendahl H; von Frankenberg M; Lemasters J J
Kupffer cell-dependent reperfusion injury in liver transplantation: new clinically relevant use of glycine.
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():185-90.
1998: Lemasters J J; Qian T; Elmore S P; Trost L C; Nishimura Y; Herman B; Bradham C A; Brenner D A; Nieminen A L
Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy.
BioFactors (Oxford, England) 1998;8(3-4):283-5.
1997: Trost L C; Lemasters J J
Role of the mitochondrial permeability transition in salicylate toxicity to cultured rat hepatocytes: implications for the pathogenesis of Reye's syndrome.
Toxicology and applied pharmacology 1997;147(2):431-41.
1997: Qian T; Nieminen A L; Herman B; Lemasters J J
Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes.
The American journal of physiology 1997;273(6 Pt 1):C1783-92.
1997: D'Armini A M; Lemasters J J; Egan T M; Viganó M
Effect of perfusion pH on rat lung viability of non-heart beating donors.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1997;12(5):787-91.
1997: Zhong Z; Connor H; Stachlewitz R F; Frankenberg M; Mason R P; Lemasters J J; Thurman R G
Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanol.
Molecular pharmacology 1997;52(5):912-9.
1997: Lemasters J J; Nieminen A L; Qian T; Trost L C; Herman B
The mitochondrial permeability transition in toxic, hypoxic and reperfusion injury.
Molecular and cellular biochemistry 1997;174(1-2):159-65.
1997: Trollinger D R; Cascio W E; Lemasters J J
Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes.
Biochemical and biophysical research communications 1997;236(3):738-42.
1997: Jones D R; Becker R M; Hoffmann S C; Lemasters J J; Egan T M
When does the lung die? Kfc, cell viability, and adenine nucleotide changes in the circulation-arrested rat lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(1):247-52.
1997: Lemasters J J; Nieminen A L
Mitochondrial oxygen radical formation during reductive and oxidative stress to intact hepatocytes.
Bioscience reports 1997;17(3):281-91.
1997: Huynh T; Baker C C; Bracey L W; Lemasters J J
Adaptive Kupffer cell alterations after femur fracture trauma in rats.
The American journal of physiology 1997;272(6 Pt 1):G1457-62.
1997: Bradham C A; Stachlewitz R F; Gao W; Qian T; Jayadev S; Jenkins G; Hannun Y; Lemasters J J; Thurman R G; Brenner D A
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases.
Hepatology (Baltimore, Md.) 1997;25(5):1128-35.
1997: Nieminen A L; Byrne A M; Herman B; Lemasters J J
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species.
The American journal of physiology 1997;272(4 Pt 1):C1286-94.
1997: Frankenberg M V; Forman D T; Frey W; Bunzendahl H; Lemasters J J; Thurman R G
Amino acids in storage solution predict primary nonfunction in fatty liver grafts.
Transplantation proceedings 1997;29(1-2):1331-2.
1997: Bachmann S; Bechstein W O; Keck H; Lemmens H P; Brandes N; John A K; Lemasters J J; Neuhaus P
Pilot study: Carolina Rinse Solution improves graft function after orthotopic liver transplantation in humans.
Transplantation proceedings 1997;29(1-2):390-2.
1997: Harrison-Shostak D C; Lemasters J J; Edgell C J; Herman B
Role of ICE-like proteases in endothelial cell hypoxic and reperfusion injury.
Biochemical and biophysical research communications 1997;231(3):844-7.
1997: Rudolph J G; Lemasters J J; Crews F T
Use of a multiwell fluorescence scanner with propidium iodide to assess NMDA mediated excitotoxicity in rat cortical neuronal cultures.
Neuroscience letters 1997;221(2-3):149-52.
1997: Lemasters J J; Thurman R G
Reperfusion injury after liver preservation for transplantation.
Annual review of pharmacology and toxicology 1997;37():327-38.
1996: Currin R T; Caldwell-Kenkel J C; Lichtman S N; Bachmann S; Takei Y; Kawano S; Thurman R G; Lemasters J J
Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation.
Transplantation 1996;62(11):1549-58.
1996: Nieminen A L; Petrie T G; Lemasters J J; Selman W R
Cyclosporin A delays mitochondrial depolarization induced by N-methyl-D-aspartate in cortical neurons: evidence of the mitochondrial permeability transition.
Neuroscience 1996;75(4):993-7.
1996: Lichtman S N; Wang J; Zhang C; Lemasters J J
Endocytosis and Ca2+ are required for endotoxin-stimulated TNF-alpha release by rat Kupffer cells.
The American journal of physiology 1996;271(5 Pt 1):G920-8.
1996: D'Armini A M; Lemasters J J; Egan T M
Studies of rat lung viability and adenine nucleotide metabolism after death.
The Annals of thoracic surgery 1996;62(5):1448-53.
1996: Zhong Z; Connor H; Mason R P; Qu W; Stachlewitz R F; Gao W; Lemasters J J; Thurman R G
Destruction of Kupffer cells increases survival and reduces graft injury after transplantation of fatty livers from ethanol-treated rats.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1996;2(5):383-7.
1996: Wang H; Harrison-Shostak D C; Lemasters J J; Herman B
Contribution of pH-dependent group II phospholipase A2 to chemical hypoxic injury in rat hepatocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(11):1319-25.
1996: Trost L C; Lemasters J J
The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1000-5.
1996: D'Armini A M; Roberts C S; Lemasters J J; Egan T M
Lung retrieval from cadaver donors with nonbeating hearts: optimal preservation solution.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(5):496-505.
1996: Hennington M H; D'Armini A M; Lemasters J J; Egan T M
Cadaver lungs for transplantation. Effect of ventilation with alveolar gas.
Transplantation 1996;61(7):1009-14.
1996: Roberts C S; Hennington M H; D'Armini A M; Griffith P K; Lemasters J J; Egan T M
Donor lungs from ventilated cadavers: impart of a free radical scavenger.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(3):275-82.
1996: Chacon E; Ohata H; Harper I S; Trollinger D R; Herman B; Lemasters J J
Mitochondrial free calcium transients during excitation-contraction coupling in rabbit cardiac myocytes.
FEBS letters 1996;382(1-2):31-6.
1996: Wang H; Harrison-Shostak D C; Lemasters J J; Herman B
Down-regulation of HCW9 mRNA in rat hepatocytes during chemical hypoxia involves both transcriptional and posttranscriptional mechanisms.
Biochemical and biophysical research communications 1996;218(1):360-4.
1996: Lemasters J J; Bond J M; Chacon E; Harper I S; Kaplan S H; Ohata H; Trollinger D R; Herman B; Cascio W E
The pH paradox in ischemia-reperfusion injury to cardiac myocytes.
EXS 1996;76():99-114.
1996: Thurman R G; Gao W; Connor H D; Adachi Y; Stachlewitz R F; Zhong Z; Knecht K T; Bradford B U; Mason R P; Lemasters J J
Role of free radicals in failure of fatty livers following liver transplantation and alcoholic liver injury.
Advances in experimental medicine and biology 1996;387():231-41.
1995: Zhong Z; Connor H D; Mason R P; Qu W; Gao W; Lemasters J J; Thurman R G
Role of Kupffer cells in reperfusion injury in fat-loaded livers from ethanol-treated rats.
The Journal of pharmacology and experimental therapeutics 1995;275(3):1512-7.
1995: Wang H; Harrison-Shostak D C; Lemasters J J; Herman B
Cloning of a rat cDNA encoding a novel LIM domain protein with high homology to rat RIL.
Gene 1995;165(2):267-71.
1995: D'Armini A M; Tom E J; Roberts C S; Henke D C; Lemasters J J; Egan T M
When does the lung die? Time course of high energy phosphate depletion and relationship to lung viability after "death".
The Journal of surgical research 1995;59(4):468-74.
1995: Wang H; Lemasters J J; Herman B
Cloning of a rat cDNA encoding a protein with high homology to mouse phospholipase A2-activating protein.
Gene 1995;161(2):237-41.
1995: Peng X X; Currin R T; Thurman R G; Lemasters J J
Protection by pentoxifylline against normothermic liver ischemia/reperfusion in rats.
Transplantation 1995;59(11):1537-41.
1995: Zahrebelski G; Nieminen A L; al-Ghoul K; Qian T; Herman B; Lemasters J J
Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: a laser scanning confocal microscopic study.
Hepatology (Baltimore, Md.) 1995;21(5):1361-72.
1995: Nieminen A L; Saylor A K; Tesfai S A; Herman B; Lemasters J J
Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide.
The Biochemical journal 1995;307 ( Pt 1)():99-106.
1995: Lemasters J J; Thurman R G
The many facets of reperfusion injury.
Gastroenterology 1995;108(4):1317-20.
1995: Lemasters J J; Bunzendahl H; Thurman R G
Reperfusion injury to donor livers stored for transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1995;1(2):124-38.
1995: Gao W; Connor H D; Lemasters J J; Mason R P; Thurman R G
Primary nonfunction of fatty livers produced by alcohol is associated with a new, antioxidant-insensitive free radical species.
Transplantation 1995;59(5):674-9.
1995: Bachmann S; Peng X X; Currin R T; Thurman R G; Lemasters J J
Glycine in Carolina rinse solution reduces reperfusion injury, improves graft function, and increases graft survival after rat liver transplantation.
Transplantation proceedings 1995;27(1):741-2.
1995: Kaplan S H; Yang H; Gilliam D E; Shen J; Lemasters J J; Cascio W E
Hypercapnic acidosis and dimethyl amiloride reduce reperfusion induced cell death in ischaemic ventricular myocardium.
Cardiovascular research 1995;29(2):231-8.
1995: Lemasters J J; Chacon E; Ohata H; Harper I S; Nieminen A L; Tesfai S A; Herman B
Measurement of electrical potential, pH, and free calcium ion concentration in mitochondria of living cells by laser scanning confocal microscopy.
Methods in enzymology 1995;260():428-44.
1995: Lemasters J J; Peng X X; Bachmann S; Currin R T; Gao W; Thurman R G
Dual role of Kupffer cell activation and endothelial cell damage in reperfusion injury to livers stored for transplantation surgery.
Journal of gastroenterology and hepatology 1995;10 Suppl 1():S84-7.
1995: Thurman R G; Gao W; Connor H D; Adachi Y; Stachlewitz R F; Zhong Z; Knecht K T; Bradford B U; Mason R P; Lemasters J J
Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury.
Journal of gastroenterology and hepatology 1995;10 Suppl 1():S24-30.
1995: Caldwell-Kenkel J C; Currin R T; Coote A; Thurman R G; Lemasters J J
Reperfusion injury to endothelial cells after cold storage of rat livers: protection by mildly acidic pH and lack of protection by antioxidants.
Transplant international : official journal of the European Society for Organ Transplantation 1995;8(2):77-85.
1994: Mehendale H M; Roth R A; Gandolfi A J; Klaunig J E; Lemasters J J; Curtis L R
Novel mechanisms in chemically induced hepatotoxicity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1994;8(15):1285-95.
1994: Huynh T; Currin R T; Tanaka Y; Lemasters J J; Baker C C
Activation of Kupffer cells in vivo following femur fracture.
Archives of surgery (Chicago, Ill. : 1960) 1994;129(12):1324-8; discussion 1328-9.
1994: Ohata H; Trollinger D R; Lemasters J J
Changes in shape and viability of cultured adult rabbit cardiac myocytes during ischemia/reperfusion injury.
Research communications in molecular pathology and pharmacology 1994;86(3):259-71.
1994: Fusaoka T; Hunt K J; Lemasters J J; Thurman R G
Evidence that activation of Kupffer cells increases oxygen uptake after cold storage.
Transplantation 1994;58(10):1067-71.
1994: D'Armini A M; Roberts C S; Griffith P K; Lemasters J J; Egan T M
When does the lung die? I. Histochemical evidence of pulmonary viability after "death".
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1994;13(5):741-7.
1994: Nieminen A L; Saylor A K; Herman B; Lemasters J J
ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition.
The American journal of physiology 1994;267(1 Pt 1):C67-74.
1994: Trost L C; Lemasters J J
A cytotoxicity assay for tumor necrosis factor employing a multiwell fluorescence scanner.
Analytical biochemistry 1994;220(1):149-53.
1994: Reinstein L J; Lichtman S N; Currin R T; Wang J; Thurman R G; Lemasters J J
Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells.
Hepatology (Baltimore, Md.) 1994;19(6):1445-52.
1994: Bond J M; Harper I S; Chacon E; Reece J M; Herman B; Lemasters J J
The pH paradox in the pathophysiology of reperfusion injury to rat neonatal cardiac myocytes.
Annals of the New York Academy of Sciences 1994;723():25-37.
1994: Lichtman S N; Wang J; Schwab J H; Lemasters J J
Comparison of peptidoglycan-polysaccharide and lipopolysaccharide stimulation of Kupffer cells to produce tumor necrosis factor and interleukin-1.
Hepatology (Baltimore, Md.) 1994;19(4):1013-22.
1994: Chacon E; Reece J M; Nieminen A L; Zahrebelski G; Herman B; Lemasters J J
Distribution of electrical potential, pH, free Ca2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: a multiparameter digitized confocal microscopic study.
Biophysical journal 1994;66(4):942-52.
1994: Hunt K J; Lemasters J J; Thurman R G
High concentrations of adenosine are needed in Carolina rinse to prevent activation of Kupffer cells.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S493-5.
1994: Savier E; Lemasters J J; Thurman R G
Kupffer cells participate in rejection following liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S183-6.
1994: Thurman R G; Gao W; Connor H D; Mason R P; Lemasters J J; Bozigian H; Adams L M
SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S167-70.
1993: Goto M; Lemasters J J; Thurman R G
Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1264-8.
1993: Lichtman S N; Bachmann S; Munoz S R; Schwab J H; Bender D E; Sartor R B; Lemasters J J
Bacterial cell wall polymers (peptidoglycan-polysaccharide) cause reactivation of arthritis.
Infection and immunity 1993;61(11):4645-53.
1993: Harper I S; Bond J M; Chacon E; Reece J M; Herman B; Lemasters J J
Inhibition of Na+/H+ exchange preserves viability, restores mechanical function, and prevents the pH paradox in reperfusion injury to rat neonatal myocytes.
Basic research in cardiology 1993;88(5):430-42.
1993: Hijioka T; Goto M; Lemasters J J; Thurman R G
Effect of short-term ethanol treatment on voltage-dependent calcium channels in Kupffer cells.
Hepatology (Baltimore, Md.) 1993;18(2):400-5.
1993: Bond J M; Chacon E; Herman B; Lemasters J J
Intracellular pH and Ca2+ homeostasis in the pH paradox of reperfusion injury to neonatal rat cardiac myocytes.
The American journal of physiology 1993;265(1 Pt 1):C129-37.
1993: Gao W; Lemasters J J; Thurman R G
Development of a new method for hepatic rearterialization in rat orthotopic liver transplantation. Reduction of liver injury and improvement of surgical outcome by arterialization.
Transplantation 1993;56(1):19-24.
1993: Imberti R; Nieminen A L; Herman B; Lemasters J J
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
The Journal of pharmacology and experimental therapeutics 1993;265(1):392-400.
1993: Dawson T L; Gores G J; Nieminen A L; Herman B; Lemasters J J
Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes.
The American journal of physiology 1993;264(4 Pt 1):C961-7.
1993: Thurman R G; Bunzendahl H; Lemasters J J
Role of sinusoidal lining cells in hepatic reperfusion injury following cold storage and transplantation.
Seminars in liver disease 1993;13(1):93-100.
1993: Currin R T; Reinstein L J; Lichtman S N; Thurman R G; Lemasters J J
Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury.
Transplantation proceedings 1993;25(1 Pt 2):1631-2.
1993: Bachmann S; Caldwell-Kenkel J C; Currin R T; Tanaka Y; Takei Y; Marzi I; Thurman R G; Lemasters J J
Ultrastructural correlates of liver graft failure from storage injury: studies of graft protection by Carolina rinse solution and pentoxifylline.
Transplantation proceedings 1993;25(1 Pt 2):1620-4.
1993: Sanchez-Urdazpal L; Gores G J; Lemasters J J; Thurman R G; Steers J L; Wahlstrom H E; Hay E I; Porayko M K; Wiesner R H; Krom R A
Carolina rinse solution decreases liver injury during clinical liver transplantation.
Transplantation proceedings 1993;25(1 Pt 2):1574-5.
1992: Imberti R; Nieminen A L; Herman B; Lemasters J J
Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals.
Research communications in chemical pathology and pharmacology 1992;78(1):27-38.
1992: Yamanaka H; Nukina S; Handler J A; Currin R T; Lemasters J J; Thurman R G
Transient activation of hepatic glycogenolysis by thrombin in perfused rat livers.
European journal of biochemistry / FEBS 1992;208(3):753-9.
1992: Nieminen A L; Gores G J; Bond J M; Imberti R; Herman B; Lemasters J J
A novel cytotoxicity screening assay using a multiwell fluorescence scanner.
Toxicology and applied pharmacology 1992;115(2):147-55.
1992: Connor H D; Gao W; Nukina S; Lemasters J J; Mason R P; Thurman R G
Evidence that free radicals are involved in graft failure following orthotopic liver transplantation in the rat--an electron paramagnetic resonance spin trapping study.
Transplantation 1992;54(2):199-204.
1992: Bachmann S; Caldwell-Kenkel J C; Oleksy I; Steffen R; Thurman R G; Lemasters J J
Warm Carolina rinse solution prevents graft failure from storage injury after orthotopic rat liver transplantation with arterialization.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5(2):108-14.
1992: Hijioka T; Rosenberg R L; Lemasters J J; Thurman R G
Kupffer cells contain voltage-dependent calcium channels.
Molecular pharmacology 1992;41(3):435-40.
1992: Lindert K A; Caldwell-Kenkel J C; Nukina S; Lemasters J J; Thurman R G
Activation of Kupffer cells on reperfusion following hypoxia: particle phagocytosis in a low-flow, reflow model.
The American journal of physiology 1992;262(2 Pt 1):G345-50.
1992: Savier E; Shedlofsky S I; Swim A T; Lemasters J J; Thurman R G
The calcium channel blocker nisoldipine minimizes the release of tumor necrosis factor and interleukin-6 following rat liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S398-402.
1992: Gao W; Lemasters J J; Thurman R G
The second generation of Carolina Rinse, solution II, improves graft survival following orthotopic liver transplantation in the rat by preventing reperfusion injury.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S362-5.
1992: Bachmann S; Caldwell-Kenkel J C; Currin R T; Lichtman S N; Steffen R; Thurman R G; Lemasters J J
Protection by pentoxifylline against graft failure from storage injury after orthotopic rat liver transplantation with arterialization.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S345-50.
1992: Gao W; Currin R J; Lemasters J J; Connor H D; Mason R P; Thurman R G
Reperfusion rather than storage injury predominates following long-term (48 h) cold storage of grafts in UW solution: studies with Carolina Rinse in transplanted rat liver.
Transplant international : official journal of the European Society for Organ Transplantation 1992;5 Suppl 1():S329-35.
1991: Marzi I; Cowper K; Takei Y; Lindert K; Lemasters J J; Thurman R G
Methyl palmitate prevents Kupffer cell activation and improves survival after orthotopic liver transplantation in the rat.
Transplant international : official journal of the European Society for Organ Transplantation 1991;4(4):215-20.
1991: Gao W S; Hijioka T; Lindert K A; Caldwell-Kenkel J C; Lemasters J J; Thurman R G
Evidence that adenosine is a key component in Carolina rinse responsible for reducing graft failure after orthotopic liver transplantation in the rat.
Transplantation 1991;52(6):992-8.
1991: Geeraerts M D; Ronveaux-Dupal M F; Lemasters J J; Herman B
Cytosolic free Ca2+ and proteolysis in lethal oxidative injury in endothelial cells.
The American journal of physiology 1991;261(5 Pt 1):C889-96.
1991: Lemasters J J; Thurman R G
Reperfusion injury: a role for neutrophils.
Hepatology (Baltimore, Md.) 1991;14(5):954-5.
1991: Kawanishi T; Nieminen A L; Herman B; Lemasters J J
Suppression of Ca2+ oscillations in cultured rat hepatocytes by chemical hypoxia.
The Journal of biological chemistry 1991;266(30):20062-9.
1991: Bond J M; Herman B; Lemasters J J
Protection by acidotic pH against anoxia/reoxygenation injury to rat neonatal cardiac myocytes.
Biochemical and biophysical research communications 1991;179(2):798-803.
1991: Gao W S; Takei Y; Marzi I; Lindert K A; Caldwell-Kenkel J C; Currin R T; Tanaka Y; Lemasters J J; Thurman R G
Carolina rinse solution--a new strategy to increase survival time after orthotopic liver transplantation in the rat.
Transplantation 1991;52(3):417-24.
1991: Takei Y; Gao W S; Hijioka T; Savier E; Lindert K A; Lemasters J J; Thurman R G
Increase in survival of liver grafts after rinsing with warm Ringer's solution due to improvement of hepatic microcirculation.
Transplantation 1991;52(2):225-30.
1991: te Koppele J M; Keller B J; Caldwell-Kenkel J C; Lemasters J J; Thurman R G
Effect of hepatotoxic chemicals and hypoxia on hepatic nonparenchymal cells: impairment of phagocytosis by Kupffer cells and disruption of the endothelium in rat livers perfused with colloidal carbon.
Toxicology and applied pharmacology 1991;110(1):20-30.
1991: Takei Y; Marzi I; Gao W S; Gores G J; Lemasters J J; Thurman R G
Leukocyte adhesion and cell death following orthotopic liver transplantation in the rat.
Transplantation 1991;51(5):959-65.
1991: Florine-Casteel K; Lemasters J J; Herman B
Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(7):2078-84.
1991: Ganey P E; Keller B; Lichtman S N; Lemasters J J; Thurman R G
A new method to monitor Kupffer cell phagocytosis continuously in perfused rat liver.
Hepatology (Baltimore, Md.) 1991;13(3):567-74.
1991: Bond J M; Herman B; Lemasters J J
Recovery of cultured rat neonatal myocytes from hypercontracture after chemical hypoxia.
Research communications in chemical pathology and pharmacology 1991;71(2):195-208.
1991: Currin R T; Gores G J; Thurman R G; Lemasters J J
Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(2):207-10.
1991: Gao W; Takei Y; Marzi I; Currin R T; Lemasters J J; Thurman R G
Carolina rinse solution increases survival time dramatically after orthotopic liver transplantation in the rat.
Transplantation proceedings 1991;23(1 Pt 1):648-50.
1991: Currin R T; Thurman R G; Lemasters J J
Carolina rinse solution protects adenosine triphosphate-depleted hepatocytes against lethal cell injury.
Transplantation proceedings 1991;23(1 Pt 1):645-7.
1991: Caldwell-Kenkel J C; Currin R T; Tanaka Y; Thurman R G; Lemasters J J
Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion.
Hepatology (Baltimore, Md.) 1991;13(1):83-95.
1991: Harrison D C; Lemasters J J; Herman B
A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes.
Biochemical and biophysical research communications 1991;174(2):654-9.
1990: Currin R T; Toole J G; Thurman R G; Lemasters J J
Evidence that Carolina rinse solution protects sinusoidal endothelial cells against reperfusion injury after cold ischemic storage of rat liver.
Transplantation 1990;50(6):1076-8.
1990: Kehrer J P; Jones D P; Lemasters J J; Farber J L; Jaeschke H
Mechanisms of hypoxic cell injury. Summary of the symposium presented at the 1990 annual meeting of the Society of Toxicology.
Toxicology and applied pharmacology 1990;106(2):165-78.
1990: Takei Y; Marzi I; Kauffman F C; Cowper K; Lemasters J J; Thurman R G
Prevention of early graft failure by the calcium channel blocker nisoldipine: involvement of Kupffer cells.
Transplantation proceedings 1990;22(5):2202-3.
1990: Kost L J; Gores G J; Sayles J M; Miller L J; Lemasters J J; Herman B; LaRusso N F
Lack of metabolic effects of cholecystokinin on hepatocytes.
Hepatology (Baltimore, Md.) 1990;12(2):301-5.
1990: Marzi I; Takei Y; Knee J; Menger M; Gores G J; Bühren V; Trentz O; Lemasters J J; Thurman R G
Assessment of reperfusion injury by intravital fluorescence microscopy following liver transplantation in the rat.
Transplantation proceedings 1990;22(4):2004-5.
1990: Harman A W; Nieminen A L; Lemasters J J; Herman B
Cytosolic free magnesium, ATP and blebbing during chemical hypoxia in cultured rat hepatocytes.
Biochemical and biophysical research communications 1990;170(2):477-83.
1990: Takei Y; Marzi I; Kauffman F C; Currin R T; Lemasters J J; Thurman R G
Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker, nisoldipine.
Transplantation 1990;50(1):14-20.
1990: Lemasters J J; Nieminen A L; Herman B
Is there release of mitochondrial calcium in toxic injury?
Hepatology (Baltimore, Md.) 1990;11(5):902-3.
1990: Gores G J; Herman B; Lemasters J J
Plasma membrane bleb formation and rupture: a common feature of hepatocellular injury.
Hepatology (Baltimore, Md.) 1990;11(4):690-8.
1990: Nieminen A L; Dawson T L; Gores G J; Kawanishi T; Herman B; Lemasters J J
Protection by acidotic pH and fructose against lethal injury to rat hepatocytes from mitochondrial inhibitors, ionophores and oxidant chemicals.
Biochemical and biophysical research communications 1990;167(2):600-6.
1990: Lemasters J J; Gores G J; Nieminen A L; Dawson T L; Wray B E; Herman B
Multiparameter digitized video microscopy of toxic and hypoxic injury in single cells.
Environmental health perspectives 1990;84():83-94.
1990: Cowper K B; Currin R T; Dawson T L; Lindert K A; Lemasters J J; Thurman R G
A new method to monitor Kupffer-cell function continuously in the perfused rat liver. Dissociation of glycogenolysis from particle phagocytosis.
The Biochemical journal 1990;266(1):141-7.
1990: Roe M W; Lemasters J J; Herman B
Assessment of Fura-2 for measurements of cytosolic free calcium.
Cell calcium 1990;11(2-3):63-73.
1990: Nieminen A L; Gores G J; Dawson T L; Herman B; Lemasters J J
Toxic injury from mercuric chloride in rat hepatocytes.
The Journal of biological chemistry 1990;265(4):2399-408.
1990: Herman B; Gores G J; Nieminen A L; Kawanishi T; Harman A; Lemasters J J
Calcium and pH in anoxic and toxic injury.
Critical reviews in toxicology 1990;21(2):127-48.
1989: Marzi I; Zhong Z; Lemasters J J; Thurman R G
Evidence that graft survival is not related to parenchymal cell viability in rat liver transplantation. The importance of nonparenchymal cells.
Transplantation 1989;48(3):463-8.
1989: Caldwell-Kenkel J C; Currin R T; Tanaka Y; Thurman R G; Lemasters J J
Reperfusion injury to endothelial cells following cold ischemic storage of rat livers.
Hepatology (Baltimore, Md.) 1989;10(3):292-9.
1989: Gores G J; Flarsheim C E; Dawson T L; Nieminen A L; Herman B; Lemasters J J
Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes.
The American journal of physiology 1989;257(2 Pt 1):C347-54.
1989: Zhong Z; Lemasters J J; Thurman R G
Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver.
The Journal of pharmacology and experimental therapeutics 1989;250(2):470-5.
1989: Marzi I; Zhi Z N; Zimmermann F A; Lemasters J J; Thurman R G
Xanthine and hypoxanthine accumulation during storage may contribute to reperfusion injury following liver transplantation in the rat.
Transplantation proceedings 1989;21(1 Pt 2):1319-20.
1989: Gores G J; Nieminen A L; Wray B E; Herman B; Lemasters J J
Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death.
The Journal of clinical investigation 1989;83(2):386-96.
1988: Nieminen A L; Gores G J; Wray B E; Tanaka Y; Herman B; Lemasters J J
Calcium dependence of bleb formation and cell death in hepatocytes.
Cell calcium 1988;9(5-6):237-46.
1988: Thurman R G; Marzi I; Seitz G; Thies J; Lemasters J J; Zimmerman F
Hepatic reperfusion injury following orthotopic liver transplantation in the rat.
Transplantation 1988;46(4):502-6.
1988: Gores G J; Nieminen A L; Fleishman K E; Dawson T L; Herman B; Lemasters J J
Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes.
The American journal of physiology 1988;255(3 Pt 1):C315-22.
1988: Stine K E; Reiter L W; Lemasters J J
Alkyltin inhibition of ATPase activities in tissue homogenates and subcellular fractions from adult and neonatal rats.
Toxicology and applied pharmacology 1988;94(3):394-406.
1988: Marotto M E; Thurman R G; Lemasters J J
Early midzonal cell death during low-flow hypoxia in the isolated, perfused rat liver: protection by allopurinol.
Hepatology (Baltimore, Md.) 1988;8(3):585-90.
1988: Caldwell-Kenkel J C; Thurman R G; Lemasters J J
Selective loss of nonparenchymal cell viability after cold ischemic storage of rat livers.
Transplantation 1988;45(4):834-7.
1988: Herman B; Nieminen A L; Gores G J; Lemasters J J
Irreversible injury in anoxic hepatocytes precipitated by an abrupt increase in plasma membrane permeability.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(2):146-51.
1988: Thurman R G; Apel E; Badr M; Lemasters J L
Protection of liver by calcium entry blockers.
Annals of the New York Academy of Sciences 1988;522():757-70.
1988: Thurman R G; Lemasters J J
New micro-optical methods to study metabolism in periportal and pericentral regions of the liver lobule.
Drug metabolism reviews 1988;19(3-4):263-81.
1988: Thurman R G; Apel E D; Lemasters J J
Protective effect of nitrendipine against hypoxic injury in perfused livers from ethanol-treated rats.
Journal of cardiovascular pharmacology 1988;12 Suppl 4():S113-6.
1987: Anundi I; King J; Owen D A; Schneider H; Lemasters J J; Thurman R G
Fructose prevents hypoxic cell death in liver.
The American journal of physiology 1987;253(3 Pt 1):G390-6.
1987: Anundi I; King J; Owens D A; Schneider H; Lemasters J J; Thurman R G
Total protection from hypoxic liver damage by fructose.
Research communications in chemical pathology and pharmacology 1987;55(1):111-6.
1987: Lemasters J J; DiGuiseppi J; Nieminen A L; Herman B
Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes.
Nature 1987;325(6099):78-81.
1987: Lemasters J J; Fleishman K E
An ATP/2e-stoichiometry of 1 1/2 is thermodynamically possible for site 3 of oxidative phosphorylation.
Biochemical and biophysical research communications 1987;142(1):176-82.
1986: Emaus R K; Grunwald R; Lemasters J J
Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties.
Biochimica et biophysica acta 1986;850(3):436-48.
1986: Bradford B U; Marotto M; Lemasters J J; Thurman R G
New, simple models to evaluate zone-specific damage due to hypoxia in the perfused rat liver: time course and effect of nutritional state.
The Journal of pharmacology and experimental therapeutics 1986;236(1):263-8.
1984: Lemasters J J
The ATP-to-oxygen stoichiometries of oxidative phosphorylation by rat liver mitochondria. An analysis of ADP-induced oxygen jumps by linear nonequilibrium thermodynamics.
The Journal of biological chemistry 1984;259(21):13123-30.
1984: Freedman J A; Lemasters J J
Thermodynamics of reverse electron transfer across site 1: ATP/2e- is greater than one.
Biochemical and biophysical research communications 1984;125(1):8-13.
1984: Thurman R G; Ji S; Matsumura T; Lemasters J J
Is hypoxia involved in the mechanism of alcohol-induced liver injury?
Fundamental and applied toxicology : official journal of the Society of Toxicology 1984;4(2 Pt 1):125-33.
1984: Lemasters J J; Grunwald R; Emaus R K
Thermodynamic limits to the ATP/site stoichiometries of oxidative phosphorylation by rat liver mitochondria.
The Journal of biological chemistry 1984;259(5):3058-63.
1984: Thurman R G; Ji S; Lemasters J J
Alcohol-induced liver injury. The role of oxygen.
Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 1984;2():103-17.
1983: Belinsky S A; Kauffman F C; Ji S; Lemasters J J; Thurman R G
Stimulation of mixed-function oxidation of 7-ethoxycoumarin in periportal and pericentral regions of the perfused rat liver by xylitol.
European journal of biochemistry / FEBS 1983;137(1-2):1-6.
1983: Lemasters J J; Stemkowski C J; Ji S; Thurman R G
Cell surface changes and enzyme release during hypoxia and reoxygenation in the isolated, perfused rat liver.
The Journal of cell biology 1983;97(3):778-86.
1983: Ji S; Lemasters J J; Christenson V; Thurman R G
Selective increase in pericentral oxygen gradient in perfused rat liver following ethanol treatment.
Pharmacology, biochemistry, and behavior 1983;18 Suppl 1():439-42.
1983: Lemasters J J; Ji S; Stemkowski C J; Thurman R G
Hypoxic hepatocellular injury.
Pharmacology, biochemistry, and behavior 1983;18 Suppl 1():455-9.
1983: Thurman R G; Kauffman F C; Ji S; Lemasters J J; Conway J G; Belinsky S A; Kashiwagi T; Matsamura T
Metabolic heterogeneity in the perfused rat liver.
Pharmacology, biochemistry, and behavior 1983;18 Suppl 1():415-9.
1983: Jacobs K S; Lemasters J J; Reiter L W
Inhibition of ATPase activities of brain and liver homogenates by triethyltin (TET).
Developments in toxicology and environmental science 1983;11():517-20.
1982: Ji S; Lemasters J J; Christenson V; Thurman R G
Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver: evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5415-9.
1982: Schneider H; Lemasters J J; Hackenbrock C R
Lateral diffusion of ubiquinone during electron transfer in phospholipid- and ubiquinone-enriched mitochondrial membranes.
The Journal of biological chemistry 1982;257(18):10789-93.
1982: Kashiwagi T; Ji S; Lemasters J J; Thurman R G
Rates of alcohol dehydrogenase-dependent ethanol metabolism in periportal and pericentral regions of the perfused rat liver.
Molecular pharmacology 1982;21(2):438-43.
1981: Lemasters J J; Billica W H
Non-equilibrium thermodynamics of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria.
The Journal of biological chemistry 1981;256(24):12949-57.
1981: Lemasters J J; Ji S; Thurman R G
Centrilobular injury following hypoxia in isolated, perfused rat liver.
Science (New York, N.Y.) 1981;213(4508):661-3.
1981: Ji S; Lemasters J J; Thurman R G
A fluorometric method to measure sublobular rates of mixed-function oxidation in the hemoglobin-free perfused rat liver.
Molecular pharmacology 1981;19(3):513-6.
1980: Lemasters J J; Hackenbrock C R
The energized state of rat liver mitochondria. ATP equivalence, uncoupler sensitivity, and decay kinetics.
The Journal of biological chemistry 1980;255(12):5674-80.
1980: Ji S; Lemasters J J; Thurman R G
A non-invasive method to study metabolic events within sublobular regions of hemoglobin-free perfused liver.
FEBS letters 1980;113(1):37-42.
1980: Schneider H; Lemasters J J; Höchli M; Hackenbrock C R
Liposome-mitochondrial inner membrane fusion. Lateral diffusion of integral electron transfer components.
The Journal of biological chemistry 1980;255(8):3748-56.
1980: Lemasters J J
Near thermodynamic equilibrium of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria.
FEBS letters 1980;110(1):96-100.
1980: Schneider H; Lemasters J J; Höchli M; Hackenbrock C R
Fusion of liposomes with mitochondrial inner membranes.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(1):442-6.
1980: Hackenbrock C R; Schneider H; Lemasters J J; Höchli M
Relationships between bilayer lipid, motional freedom of oxidoreductase components, and electron transfer in the mitochondrial inner membrane.
Advances in experimental medicine and biology 1980;132():245-63.
1980: Ji S; Lemasters J J; Thurman R G
Ethanol-induced changes in the intralobular oxygen gradient of perfused rat liver.
Pharmacology, biochemistry, and behavior 1980;13 Suppl 1():41-5.
1979: Lemasters J J; Sowers A E
Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting.
The Journal of biological chemistry 1979;254(4):1248-51.
1979: Lemasters J J; Hackenbrock C R
Continuous measurement of adenosine triphosphate with firefly luciferase luminescence.
Methods in enzymology 1979;56():530-44.
1978: Lemasters J J
Possible role of the mitochondrial outer membrane as an oncotic regulator of mitochondrial volume.
FEBS letters 1978;88(1):10-4.
1977: Lemasters J J; Hackenbrock C R
Kinetics of product inhibition during firefly luciferase luminescence.
Biochemistry 1977;16(3):445-7.
1976: Lemasters J J; Hackenbrock C R
Continuous measurement and rapid kinetics of ATP synthesis in rat liver mitochondria, mitoplasts and inner membrane vesicles determined by firefly-luciferase luminescence.
European journal of biochemistry / FEBS 1976;67(1):1-10.
1973: Lemasters J J; Hackenbrock C E
Adenosine triphosphate: continuous measurement in mitochondrial suspension by firefly luciferase luminescence.
Biochemical and biophysical research communications 1973;55(4):1262-70.
1971: Hackenbrock C R; Rehn T G; Weinbach E C; Lemasters J J
Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumor cell.
The Journal of cell biology 1971;51(1):123-37.

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