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Glen Barber

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
17
Balachandran, Siddharth
15
Katze, Michael
6
Hovanessian, Ara
5
Jagus, Rosemary
5
Ezelle, Heather
4
Diaz, Rosa Maria
4
Hunt, Kelly
4
Harrington, William
4
Kottke, Timothy
4
Vorburger, Stephan
4
Pataer, Abujiang
4
Swisher, Stephen
4
Thompson, Jill
4
Vile, Richard
3
Toomey, Ngoc

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Publications

TOP 3
Barral Paola M; Sarkar Devanand; Su Zao-zhong; Barber Glen N; DeSalle Rob; Racaniello Vincent R; Fisher Paul B
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity.
Ishikawa Hiroki; Ma Zhe; Barber Glen N
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Chakraborty Papia; Seemann Joachim; Mishra Ram K; Wei Jen-Hsuan; Weil Lauren; Nussenzveig Daniel R; Heiber Joshua; Barber Glen N; Dasso Mary; Fontoura Beatriz M A
Vesicular stomatitis virus inhibits mitotic progression and triggers cell death.

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All Publications

2009: Barral Paola M; Sarkar Devanand; Su Zao-zhong; Barber Glen N; DeSalle Rob; Racaniello Vincent R; Fisher Paul B
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity.
Pharmacology & therapeutics 2009;124(2):219-34.
2009: Ishikawa Hiroki; Ma Zhe; Barber Glen N
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Nature 2009;461(7265):788-92.
2009: Chakraborty Papia; Seemann Joachim; Mishra Ram K; Wei Jen-Hsuan; Weil Lauren; Nussenzveig Daniel R; Heiber Joshua; Barber Glen N; Dasso Mary; Fontoura Beatriz M A
Vesicular stomatitis virus inhibits mitotic progression and triggers cell death.
EMBO reports 2009;10(10):1154-60.
2009: Barber Glen N
The NFAR's (nuclear factors associated with dsRNA): evolutionarily conserved members of the dsRNA binding protein family.
RNA biology 2009;6(1):35-9.
2008: Kottke Timothy; Diaz Rosa M; Kaluza Karen; Pulido Jose; Galivo Feorillo; Wongthida Phonphimon; Thompson Jill; Willmon Candice; Barber Glen N; Chester John; Selby Peter; Strome Scott; Harrington Kevin; Melcher Alan; Vile Richard G
Use of biological therapy to enhance both virotherapy and adoptive T-cell therapy for cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(12):1910-8.
2008: Ishikawa Hiroki; Barber Glen N
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Nature 2008;455(7213):674-8.
2008: Kottke Timothy; Galivo Feorillo; Wongthida Phonphimon; Diaz Rosa Maria; Thompson Jill; Jevremovic Dragan; Barber Glen N; Hall Geoff; Chester John; Selby Peter; Harrington Kevin; Melcher Alan; Vile Richard G
Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(7):1217-26.
2008: Pfeifer Ingrid; Elsby Rachel; Fernandez Marilyn; Faria Paula A; Nussenzveig Daniel R; Lossos Izidor S; Fontoura Beatriz M A; Martin W David; Barber Glen N
NFAR-1 and -2 modulate translation and are required for efficient host defense.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4173-8.
2008: Hickman Heather D; Takeda Kazuyo; Skon Cara N; Murray Faith R; Hensley Scott E; Loomis Joshua; Barber Glen N; Bennink Jack R; Yewdell Jonathan W
Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes.
Nature immunology 2008;9(2):155-65.
2008: Qiao Jian; Kottke Timothy; Willmon Candice; Galivo Feorillo; Wongthida Phonphimon; Diaz Rosa Maria; Thompson Jill; Ryno Pamela; Barber Glen N; Chester John; Selby Peter; Harrington Kevin; Melcher Alan; Vile Richard G
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy.
Nature medicine 2008;14(1):37-44.
2007: von Holzen Urs; Pataer Abujiang; Raju Uma; Bocangel Dora; Vorburger Stephan A; Liu Yanna; Lu Xiaolin; Roth Jack A; Aggarwal Bharat B; Barber Glen N; Keyomarsi Khandan; Hunt Kelly K; Swisher Stephen G
The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6032-9.
2007: Sarkar Devanand; Park Eun Sook; Barber Glen N; Fisher Paul B
Activation of double-stranded RNA dependent protein kinase, a new pathway by which human polynucleotide phosphorylase (hPNPase(old-35)) induces apoptosis.
Cancer research 2007;67(17):7948-53.
2007: Andrews Nicolas P; Pack Christopher D; Vezys Vaiva; Barber Glen N; Lukacher Aron E
Early virus-associated bystander events affect the fitness of the CD8 T cell response to persistent virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7267-75.
2007: Venkataraman Thiagarajan; Valdes Maikel; Elsby Rachel; Kakuta Shigeru; Caceres Gisela; Saijo Shinobu; Iwakura Yoichiro; Barber Glen N
Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6444-55.
2007: Greidinger Eric L; Zang YunJuan; Martinez Laisel; Jaimes Kimberly; Nassiri Mehdi; Bejarano Pablo; Barber Glen N; Hoffman Robert W
Differential tissue targeting of autoimmunity manifestations by autoantigen-associated Y RNAs.
Arthritis and rheumatism 2007;56(5):1589-97.
2007: Diaz Rosa Maria; Galivo Feorillo; Kottke Timothy; Wongthida Phonphimon; Qiao Jian; Thompson Jill; Valdes Mikael; Barber Glen; Vile Richard G
Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus.
Cancer research 2007;67(6):2840-8.
2007: Radtke Andrea L; Delbridge Laura M; Balachandran Siddharth; Barber Glen N; O'Riordan Mary X D
TBK1 protects vacuolar integrity during intracellular bacterial infection.
PLoS pathogens 2007;3(3):e29.
2007: Goodman Alan G; Smith Jennifer A; Balachandran Siddharth; Perwitasari Olivia; Proll Sean C; Thomas Matthew J; Korth Marcus J; Barber Glen N; Schiff Leslie A; Katze Michael G
The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism.
Journal of virology 2007;81(5):2221-30.
2007: Balachandran Siddharth; Venkataraman Thiagarajan; Fisher Paul B; Barber Glen N
Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of Irf7.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2429-39.
2007: Balachandran Siddharth; Barber Glen N
PKR in innate immunity, cancer, and viral oncolysis.
Methods in molecular biology (Clifton, N.J.) 2007;383():277-301.
2006: Lin L; Su Z; Lebedeva I V; Gupta P; Boukerche H; Rai T; Barber G N; Dent P; Sarkar D; Fisher P B
Activation of Ras/Raf protects cells from melanoma differentiation-associated gene-5-induced apoptosis.
Cell death and differentiation 2006;13(11):1982-93.
2006: Majid Ayaz M; Ezelle Heather; Shah Sangeeta; Barber Glen N
Evaluating replication-defective vesicular stomatitis virus as a vaccine vehicle.
Journal of virology 2006;80(14):6993-7008.
2006: Greidinger Eric L; Zang YunJuan; Jaimes Kimberly; Hogenmiller Scott; Nassiri Mehdi; Bejarano Pablo; Barber Glen N; Hoffman Robert W
A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen.
Arthritis and rheumatism 2006;54(2):661-9.
2005: Barber Glen N
VSV-tumor selective replication and protein translation.
Oncogene 2005;24(52):7710-9.
2005: Kurokawa Motoki; Ghosh Subrata K; Ramos Juan Carlos; Mian Abdul M; Toomey Ngoc L; Cabral Lisa; Whitby Denise; Barber Glen N; Dittmer Dirk P; Harrington William J
Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma.
Blood 2005;106(1):235-40.
2005: Barber G N
The dsRNA-dependent protein kinase, PKR and cell death.
Cell death and differentiation 2005;12(6):563-70.
2005: Pataer Abujiang; Vorburger Stephan A; Chada Sunil; Balachandran Siddharth; Barber Glen N; Roth Jack A; Hunt Kelly K; Swisher Stephen G
Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(5):717-23.
2005: Faria Paula A; Chakraborty Papia; Levay Agata; Barber Glen N; Ezelle Heather J; Enninga Jost; Arana Carlos; van Deursen Jan; Fontoura Beatriz M A
VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway.
Molecular cell 2005;17(1):93-102.
2004: Balachandran Siddharth; Thomas Emmanuel; Barber Glen N
A FADD-dependent innate immune mechanism in mammalian cells.
Nature 2004;432(7015):401-5.
2004: Perkins Darren J; Barber Glen N
Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblasts.
Molecular and cellular biology 2004;24(5):2025-40.
2004: Balachandran Siddharth; Barber Glen N
Defective translational control facilitates vesicular stomatitis virus oncolysis.
Cancer cell 2004;5(1):51-65.
2004: Barber Glen N
Vesicular stomatitis virus as an oncolytic vector.
Viral immunology 2004;17(4):516-27.
2003: Porosnicu Mercedes; Mian Abdul; Barber Glen N
The oncolytic effect of recombinant vesicular stomatitis virus is enhanced by expression of the fusion cytosine deaminase/uracil phosphoribosyltransferase suicide gene.
Cancer research 2003;63(23):8366-76.
2003: Obuchi Masatsugu; Fernandez Marilyn; Barber Glen N
Development of recombinant vesicular stomatitis viruses that exploit defects in host defense to augment specific oncolytic activity.
Journal of virology 2003;77(16):8843-56.
2003: Saunders Laura R; Barber Glen N
The dsRNA binding protein family: critical roles, diverse cellular functions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):961-83.
2003: Ogilvie V C; Wilson B J; Nicol S M; Morrice N A; Saunders L R; Barber G N; Fuller-Pace F V
The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells.
Nucleic acids research 2003;31(5):1470-80.
2003: Ghosh Subrata K; Wood Charles; Boise Lawrence H; Mian Abdul M; Deyev Vadim V; Feuer Gerold; Toomey Ngoc L; Shank Nicole C; Cabral Lisa; Barber Glen N; Harrington William J
Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-kappa B.
Blood 2003;101(6):2321-7.
2002: Ezelle Heather J; Markovic Dubravka; Barber Glen N
Generation of hepatitis C virus-like particles by use of a recombinant vesicular stomatitis virus vector.
Journal of virology 2002;76(23):12325-34.
2002: Vorburger Stephan A; Pataer Abujiang; Yoshida Kazumi; Barber Glen N; Xia Weiya; Chiao Paul; Ellis Lee M; Hung Mien-Chie; Swisher Stephen G; Hunt Kelly K
Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.
Oncogene 2002;21(41):6278-88.
2002: Grandvaux Nathalie; Servant Marc J; tenOever Benjamin; Sen Ganes C; Balachandran Siddarth; Barber Glen N; Lin Rongtuan; Hiscott John
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes.
Journal of virology 2002;76(11):5532-9.
2002: Pataer Abujiang; Vorburger Stephan A; Barber Glen N; Chada Sunil; Mhashilkar Abner M; Zou-Yang Helena; Stewart Alexis L; Balachandran Siddharth; Roth Jack A; Hunt Kelly K; Swisher Stephen G
Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR).
Cancer research 2002;62(8):2239-43.
2002: Fernandez Marilyn; Porosnicu Mercedes; Markovic Dubravka; Barber Glen N
Genetically engineered vesicular stomatitis virus in gene therapy: application for treatment of malignant disease.
Journal of virology 2002;76(2):895-904.
2001: Toomey N L; Deyev V V; Wood C; Boise L H; Scott D; Liu L H; Cabral L; Podack E R; Barber G N; Harrington W J
Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma.
Oncogene 2001;20(48):7029-40.
2001: Saunders L R; Perkins D J; Balachandran S; Michaels R; Ford R; Mayeda A; Barber G N
Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.
The Journal of biological chemistry 2001;276(34):32300-12.
2001: Polyak S J; Khabar K S; Paschal D M; Ezelle H J; Duverlie G; Barber G N; Levy D E; Mukaida N; Gretch D R
Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response.
Journal of virology 2001;75(13):6095-106.
2001: Balachandran S; Porosnicu M; Barber G N
Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis.
Journal of virology 2001;75(7):3474-9.
2001: Ezelle H J; Balachandran S; Sicheri F; Polyak S J; Barber G N
Analyzing the mechanisms of interferon-induced apoptosis using CrmA and hepatitis C virus NS5A.
Virology 2001;281(1):124-37.
2001: Lin R; Genin P; Mamane Y; Sgarbanti M; Battistini A; Harrington W J; Barber G N; Hiscott J
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators.
Oncogene 2001;20(7):800-11.
2001: Barber G N
Host defense, viruses and apoptosis.
Cell death and differentiation 2001;8(2):113-26.
2001: Saunders L R; Jurecic V; Barber G N
The 90- and 110-kDa human NFAR proteins are translated from two differentially spliced mRNAs encoded on chromosome 19p13.
Genomics 2001;71(2):256-9.
2000: Balachandran S; Barber G N
Vesicular stomatitis virus (VSV) therapy of tumors.
IUBMB life 2000;50(2):135-8.
2000: Balachandran S; Roberts P C; Brown L E; Truong H; Pattnaik A K; Archer D R; Barber G N
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection.
Immunity 2000;13(1):129-41.
2000: Barber G N
The interferons and cell death: guardians of the cell or accomplices of apoptosis?
Seminars in cancer biology 2000;10(2):103-11.
2000: Heylbroeck C; Balachandran S; Servant M J; DeLuca C; Barber G N; Lin R; Hiscott J
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis.
Journal of virology 2000;74(8):3781-92.
2000: Balachandran S; Roberts P C; Kipperman T; Bhalla K N; Compans R W; Archer D R; Barber G N
Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway.
Journal of virology 2000;74(3):1513-23.
1999: Taylor D R; Shi S T; Romano P R; Barber G N; Lai M M
Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein.
Science (New York, N.Y.) 1999;285(5424):107-10.
1999: Jagus R; Joshi B; Barber G N
PKR, apoptosis and cancer.
The international journal of biochemistry & cell biology 1999;31(1):123-38.
1998: Balachandran S; Kim C N; Yeh W C; Mak T W; Bhalla K; Barber G N
Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling.
The EMBO journal 1998;17(23):6888-902.
1998: Abraham N; Jaramillo M L; Duncan P I; Méthot N; Icely P L; Stojdl D F; Barber G N; Bell J C
The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.
Experimental cell research 1998;244(2):394-404.
1998: Sharp T V; Moonan F; Romashko A; Joshi B; Barber G N; Jagus R
The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation.
Virology 1998;250(2):302-15.
1996: Polyak S J; Tang N; Wambach M; Barber G N; Katze M G
The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity.
The Journal of biological chemistry 1996;271(3):1702-7.
1995: Barber G N; Jagus R; Meurs E F; Hovanessian A G; Katze M G
Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase.
The Journal of biological chemistry 1995;270(29):17423-8.
1995: Barber G N; Wambach M; Thompson S; Jagus R; Katze M G
Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation.
Molecular and cellular biology 1995;15(6):3138-46.
1995: Romano P R; Green S R; Barber G N; Mathews M B; Hinnebusch A G
Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae.
Molecular and cellular biology 1995;15(1):365-78.
1994: Barber G N; Thompson S; Lee T G; Strom T; Jagus R; Darveau A; Katze M G
The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4278-82.
1993: Barber G N; Edelhoff S; Katze M G; Disteche C M
Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17 E2.
Genomics 1993;16(3):765-7.
1993: Barber G N; Wambach M; Wong M L; Dever T E; Hinnebusch A G; Katze M G
Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4621-5.
1993: Dever T E; Chen J J; Barber G N; Cigan A M; Feng L; Donahue T F; London I M; Katze M G; Hinnebusch A G
Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4616-20.
1993: Hu S L; Stallard V; Abrams K; Barber G N; Kuller L; Langlois A J; Morton W R; Benveniste R E
Protection of vaccinia-primed macaques against SIVmne infection by combination immunization with recombinant vaccinia virus and SIVmne gp160.
Journal of medical primatology 1993;22(2-3):92-9.
1993: Black T L; Barber G N; Katze M G
Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA.
Journal of virology 1993;67(2):791-800.
1993: Meurs E F; Galabru J; Barber G N; Katze M G; Hovanessian A G
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):232-6.
1992: Barber G N; Tomita J; Garfinkel M S; Meurs E; Hovanessian A; Katze M G
Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase.
Virology 1992;191(2):670-9.
1992: Meurs E F; Watanabe Y; Kadereit S; Barber G N; Katze M G; Chong K; Williams B R; Hovanessian A G
Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth.
Journal of virology 1992;66(10):5805-14.
1992: Koromilas A E; Roy S; Barber G N; Katze M G; Sonenberg N
Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase.
Science (New York, N.Y.) 1992;257(5077):1685-9.
1992: Hu S L; Abrams K; Barber G N; Moran P; Zarling J M; Langlois A J; Kuller L; Morton W R; Benveniste R E
Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160.
Science (New York, N.Y.) 1992;255(5043):456-9.
1991: Katze M G; Wambach M; Wong M L; Garfinkel M; Meurs E; Chong K; Williams B R; Hovanessian A G; Barber G N
Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system.
Molecular and cellular biology 1991;11(11):5497-505.
1991: Barber G N; Tomita J; Hovanessian A G; Meurs E; Katze M G
Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli.
Biochemistry 1991;30(42):10356-61.
1990: Barber G N; Clegg J C; Lloyd G
Expression of the Lassa virus nucleocapsid protein in insect cells infected with a recombinant baculovirus: application to diagnostic assays for Lassa virus infection.
The Journal of general virology 1990;71 ( Pt 1)():19-28.
1989: Lloyd G; Barber G N; Clegg J C; Kelly P
Identification of Lassa fever virus infection with recombinant nucleocapsid protein antigen.
Lancet 1989;2(8673):1222.
1987: Barber G N; Clegg J C; Chamberlain J
Expression of Lassa virus nucleocapsid protein segments in bacteria: purification of high-level expression products and their application in antibody detection.
Gene 1987;56(1):137-44.
1986: Clegg J C; Barber G N; Chamberlain J F; Oram J D
Expression of Lassa virus nucleocapsid gene fragments in bacteria.
Medical microbiology and immunology 1986;175(2-3):93-5.

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