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Alex Lentsch

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Silvia Uriarte; Richard A Ward; Shunying Jin; Alex B Lentsch; Michael L Merchant; Madhavi J Rane; Kenneth R McLeish
Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.
Heather L Van Sweringen; Ralph C Quillin; Nozomu Sakai; Rebecca Schuster; Jeff Bailey; John Blanchard; Charles C Caldwell; Michael J Edwards; Holly Goetzman; Alex B Lentsch
Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice.
Nozomu Sakai; Rebecca Schuster; Amit D Tevar; Heather L Van Sweringen; John Blanchard; Justin M Burns; Michael J Edwards; R Cutler Quillin; Alex B Lentsch
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice.

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2013: Silvia Uriarte; Richard A Ward; Shunying Jin; Alex B Lentsch; Michael L Merchant; Madhavi J Rane; Kenneth R McLeish
Inhibition of neutrophil exocytosis ameliorates acute lung injury in rats.
Shock (Augusta, Ga.) 2013;39(3):286-92.
2013: Heather L Van Sweringen; Ralph C Quillin; Nozomu Sakai; Rebecca Schuster; Jeff Bailey; John Blanchard; Charles C Caldwell; Michael J Edwards; Holly Goetzman; Alex B Lentsch
Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice.
Hepatology (Baltimore, Md.) 2013;57(1):331-8.
2012: Nozomu Sakai; Rebecca Schuster; Amit D Tevar; Heather L Van Sweringen; John Blanchard; Justin M Burns; Michael J Edwards; R Cutler Quillin; Alex B Lentsch
Interleukin-33 is hepatoprotective during liver ischemia/reperfusion in mice.
Hepatology (Baltimore, Md.) 2012;56(4):1468-78.
2012: Nozomu Sakai; Rebecca Schuster; Amit D Tevar; Heather L Van Sweringen; Ritha M Belizaire; John Blanchard; Justin M Burns; Michael J Edwards; Ralph Cutler Quillin; Alex B Lentsch
Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells.
Journal of gastroenterology and hepatology 2012;27(10):1609-16.
2012: Kamyar Zahedi; Nora Steinbergs; Jiang Wang; Jie Xu; Hassane Amlal; Sharon L Barone; Robert A Casero; Alex B Lentsch; Rebecca Schuster; Manoocher Soleimani
Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury.
American journal of physiology. Gastrointestinal and liver physiology 2012;303(5):G546-60.
2012: Amy T Makley; Rebecca M Schuster; Dennis I Sonnier; Stephanie R Bailey; Ritha Belizaire; Eric M Campion; Warren C Dorlac; Lou Ann Friend; Michael D Goodman; Jay A Johannigman; Alex B Lentsch; Timothy A Pritts
Simulated aeromedical evacuation does not affect systemic inflammation or organ injury in a murine model of hemorrhagic shock.
Military medicine 2012;177(8):911-6.
2012: Ritha M Belizaire; Eric M Campion; Warren C Dorlac; Lou Ann Friend; Michael D Goodman; Alex B Lentsch; Amy T Makley; Dennis I Sonnier; Timothy A Pritts
Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage.
The journal of trauma and acute care surgery 2012;73(2 Suppl 1):S128-33.
2012: Priya S Prakash; Timothy A Pritts; Charles C Caldwell; Alex B Lentsch; Bryce R H Robinson
Human microparticles generated during sepsis in patients with critical illness are neutrophil-derived and modulate the immune response.
The journal of trauma and acute care surgery 2012;73(2):401-6; discussion 406-7.
2012: Ryan E Earnest; Alex B Lentsch; Amy T Makley; Stephanie R Bailey; Eric M Campion; Warren C Dorlac; Dennis I Sonnier; Joseph C Wenke; Timothy A Pritts
Supplemental oxygen attenuates the increase in wound bacterial growth during simulated aeromedical evacuation in goats.
The journal of trauma and acute care surgery 2012;73(1):80-6.
2012: Amy T Makley; Ritha M Belizaire; Warren C Dorlac; Lou Ann Friend; Michael D Goodman; Jay A Johannigman; Alex B Lentsch; Timothy A Pritts
Damage control resuscitation decreases systemic inflammation after hemorrhage.
The Journal of surgical research 2012;175(2):e75-82.
2012: Ritha M Belizaire; Charles C Caldwell; Michael J Edwards; Alex B Lentsch; Priya S Prakash; Jillian R Richter; Bryce R Robinson; Timothy A Pritts
Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation.
Journal of the American College of Surgeons 2012;214(4):648-55; discussion 656-7.
2012: Nathan L Huber; Alex B Lentsch; Cora K Ogle; Stephanie R Bailey; Rebecca Schuster; Timothy A Pritts
Prior thermal injury accelerates endotoxin-induced inflammatory cytokine production and intestinal nuclear factor-κB activation in mice.
Journal of burn care & research : official publication of the American Burn Association 2012;33(2):279-85.
2012: Nozomu Sakai; Rebecca Schuster; Amit D Tevar; Heather L Van Sweringen; John Blanchard; Justin M Burns; Michael J Edwards; Alex B Lentsch
Receptor activator of nuclear factor-κB ligand (RANKL) protects against hepatic ischemia/reperfusion injury in mice.
Hepatology (Baltimore, Md.) 2012;55(3):888-97.
2011: Callisia Clarke; Michael J Edwards; Nozomu Sakai; Rebecca Schuster; Amit D Tevar; Alex B Lentsch
STAT3 does not regulate acute liver injury after ischemia/reperfusion.
The Journal of surgical research 2011;171(2):814-8.
2011: Heather L Van Sweringen; Justin M Burns; Michael J Edwards; Nozomu Sakai; Amit D Tevar; Alex B Lentsch
CXC chemokine signaling in the liver: impact on repair and regeneration.
Hepatology (Baltimore, Md.) 2011;54(4):1445-53.
2011: Dennis I Sonnier; Stephanie R Bailey; Lou Ann Friend; Alex B Lentsch; Amy T Makley; Timothy A Pritts
Hemorrhagic shock induces a proinflammatory milieu in the gut lumen.
The Journal of surgical research 2011;170(2):272-9.
2011: Amit D Tevar; Jiang Wang; Callisia N Clarke; Michael J Edwards; Rebecca Schuster; Alex B Lentsch
The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis.
The Journal of surgical research 2011;169(1):e7-14.
2011: Nozomu Sakai; John Blanchard; William Thomas Johnson; Alex B Lentsch; Rebecca Schuster; Thomas Shin; Dale A Schuschke
Marginal copper deficiency increases liver neutrophil accumulation after ischemia/reperfusion in rats.
Biological trace element research 2011;142(1):47-54.
2011: N Sakai; Rebecca Schuster; Amit D Tevar; H L Van Sweringen; John Blanchard; M J Edwards; Satoshi Kuboki; Alex B Lentsch
CXCR1 deficiency does not alter liver regeneration after partial hepatectomy in mice.
Transplantation proceedings 2011;43(5):1967-70.
2011: Joshua K Elson; Jennifer L Beebe; Hal Morgenstern; Mahdavi Chilkuri; John Blanchard; Alex B Lentsch
The Duffy Antigen/Receptor for Chemokines (DARC) and prostate-cancer risk among Jamaican men.
Journal of immigrant and minority health / Center for Minority Public Health 2011;13(1):36-41.
2011: Callisia Clarke; Satoshi Kuboki; Nozomu Sakai; Kevin R Kasten; Amit D Tevar; Rebecca Schuster; John Blanchard; Charles C Caldwell; Michael J Edwards; Alex B Lentsch
CXC chemokine receptor-1 is expressed by hepatocytes and regulates liver recovery after hepatic ischemia/reperfusion injury.
Hepatology (Baltimore, Md.) 2011;53(1):261-71.
2011: Michael D Goodman; Amy T Makley; Nathan L Huber; Callisia N Clarke; Lou Ann Friend; Rebecca M Schuster; Stephanie R Bailey; Stephen L Barnes; Warren C Dorlac; Jay A Johannigman; Alex B Lentsch; Timothy A Pritts
Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury.
The Journal of surgical research 2011;165(1):30-7.
2010: Michael D Goodman; Amy T Makley; Alex B Lentsch; Stephen L Barnes; Gina R Dorlac; Warren C Dorlac; Jay A Johannigman; Timothy A Pritts
Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly?
The Journal of surgical research 2010;164(2):286-93.
2010: Dennis I Sonnier; Stephanie R Bailey; Rebecca M Schuster; Alex B Lentsch; Timothy A Pritts
TNF-α induces vectorial secretion of IL-8 in Caco-2 cells.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(10):1592-9.
2010: Nozomu Sakai; Callisia N Clarke; Rebecca Schuster; John Blanchard; Amit D Tevar; Michael J Edwards; Alex B Lentsch
Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes.
World journal of gastroenterology : WJG 2010;16(30):3816-26.
2010: Amy T Makley; Michael D Goodman; Lou Ann Friend; Jay A Johannigman; Warren C Dorlac; Alex B Lentsch; Timothy A Pritts
Murine blood banking: characterization and comparisons to human blood.
Shock (Augusta, Ga.) 2010;34(1):40-5.
2010: Amit D Tevar; Calissia Clarke; Jiang Wang; Steven M Rudich; E Steve Woodle; Alex B Lentsch; Michael L Edwards
Clinical review of nonalcoholic steatohepatitis in liver surgery and transplantation.
Journal of the American College of Surgeons 2010;210(4):515-26.
2010: Amy T Makley; Michael D Goodman; Lou Ann Friend; Joseph S Deters; Jay A Johannigman; Warren C Dorlac; Alex B Lentsch; Timothy A Pritts
Resuscitation with fresh whole blood ameliorates the inflammatory response after hemorrhagic shock.
The Journal of trauma 2010;68(2):305-11.
2010: Kevin R Kasten; Holly S Goetzman; Maria R Reid; Alison M Rasper; Samuel G Adediran; Chad T Robinson; Cynthia M Cave; Joseph S Solomkin; Alex B Lentsch; Jay A Johannigman; Charles C Caldwell
Divergent adaptive and innate immunological responses are observed in humans following blunt trauma.
BMC immunology 2010;11():4.
2009: Callisia N Clarke; Satoshi Kuboki; Amit Tevar; Alex B Lentsch; Michael Edwards
CXC chemokines play a critical role in liver injury, recovery, and regeneration.
American journal of surgery 2009;198(3):415-9.
2009: Satoshi Kuboki; Nozomu Sakai; Callisia Clarke; Rebecca Schuster; John Blanchard; Michael J Edwards; Alex B Lentsch
The peptidyl-prolyl isomerase, Pin1, facilitates NF-kappaB binding in hepatocytes and protects against hepatic ischemia/reperfusion injury.
Journal of hepatology 2009;51(2):296-306.
2009: Johannes Tschöp; Kevin R Kasten; Rubén Nogueiras; Holly S Goetzman; Cynthia M Cave; Lisa G England; Jonathan Dattilo; Alex B Lentsch; Matthias H Tschöp; Charles C Caldwell
The cannabinoid receptor 2 is critical for the host response to sepsis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):499-505.
2009: Basilia Zingarelli; Paul W Hake; Michael O'Connor; Timothy J Burroughs; Hector R Wong; Joseph S Solomkin; Alex B Lentsch
Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma.
Critical care medicine 2009;37(6):1978-87.
2009: Satoshi Kuboki; Nozomu Sakai; Johannes Tschöp; Michael J Edwards; Alex B Lentsch; Charles C Caldwell
Distinct contributions of CD4+ T cell subsets in hepatic ischemia/reperfusion injury.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(5):G1054-9.
2009: Nadine Huber; Nozomu Sakai; Thorsten Eismann; Thomas Shin; Satoshi Kuboki; John Blanchard; Rebecca Schuster; Michael J Edwards; Hector R Wong; Alex B Lentsch
Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion.
Hepatology (Baltimore, Md.) 2009;49(5):1718-28.
2009: Fereshteh Golab; Mehri Kadkhodaee; Maryam Zahmatkesh; mehdi hedayati; HA Arab; Rebecca Schuster; Kamyar Zahedi; Alex B Lentsch; Manoocher Soleimani
Ischemic and non-ischemic acute kidney injury cause hepatic damage.
Kidney international 2009;75(8):783-92.
2009: Kamyar Zahedi; Alex B Lentsch; Tomohisa Okaya; Sharon Barone; Nozomu Sakai; David P Witte; Lois J Arend; Leena Alhonen; Jason Jell; Juhani Jänne; Carl W Porter; Manoocher Soleimani
Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(4):G899-909.
2009: Jaime D Lewis; Timothy A Pritts; Alex B Lentsch; Michael J Edwards
The University of Cincinnati College of Medicine Department of Surgery.
The American surgeon 2009;75(2):113-9.
2009: Thorsten Eismann; Nadine Huber; Thomas Shin; Satoshi Kuboki; Elizabeth Galloway; Michael Wyder; Michael J Edwards; Kenneth D Greis; Howard G Shertzer; Aron B Fisher; Alex B Lentsch
Peroxiredoxin-6 protects against mitochondrial dysfunction and liver injury during ischemia-reperfusion in mice.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(2):G266-74.
2009: Michael A Flierl; Daniel Rittirsch; Brian A Nadeau; J Vidya Sarma; Danielle E Day; Alex B Lentsch; Markus Huber-Lang; Peter A Ward
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response.
PloS one 2009;4(2):e4414.
2008: Charles C Caldwell; Alex B Lentsch
Ischemia-driven expression of CD73 confers tissue protection during liver ischemia/reperfusion.
Gastroenterology 2008;135(5):1460-2.
2008: Satoshi Kuboki; Thomas Shin; Nadine Huber; Thorsten Eismann; Elizabeth Galloway; Rebecca Schuster; John Blanchard; Michael J Edwards; Alex B Lentsch
Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice.
Hepatology (Baltimore, Md.) 2008;48(4):1213-23.
2008: Elizabeth Galloway; Thomas Shin; Nadine Huber; Thorsten Eismann; Satoshi Kuboki; Rebecca Schuster; John Blanchard; Hector R Wong; Alex B Lentsch
Activation of hepatocytes by extracellular heat shock protein 72.
American journal of physiology. Cell physiology 2008;295(2):C514-20.
2008: Thomas Shin; Satoshi Kuboki; Nadine Huber; Thorsten Eismann; Elizabeth Galloway; Rebecca Schuster; John Blanchard; Timothy A Pritts; Alex B Lentsch
Activation of peroxisome proliferator-activated receptor-gamma during hepatic ischemia is age-dependent.
The Journal of surgical research 2008;147(2):200-5.
2008: Thomas Shin; Satoshi Kuboki; Alex B Lentsch
Roles of nuclear factor-kappaB in postischemic liver.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38(5):429-40.
2008: André Martignoni; Johannes Tschöp; Holly S Goetzman; Lisa G Choi; Maria D Reid; Jay A Johannigman; Alex B Lentsch; Charles C Caldwell
CD4-expressing cells are early mediators of the innate immune system during sepsis.
Shock (Augusta, Ga.) 2008;29(5):591-7.
2008: Johannes Tschöp; André Martignoni; Holly S Goetzman; Lisa G Choi; Quan Wang; J Gregory Noel; Cora K Ogle; Timothy A Pritts; Jay A Johannigman; Alex B Lentsch; Charles C Caldwell
Gammadelta T cells mitigate the organ injury and mortality of sepsis.
Journal of leukocyte biology 2008;83(3):581-8.
2008: Satoshi Kuboki; Thomas Shin; Nadine Huber; Thorsten Eismann; Elizabeth Galloway; Rebecca Schuster; John Blanchard; Basilia Zingarelli; Alex B Lentsch
Peroxisome proliferator-activated receptor-gamma protects against hepatic ischemia/reperfusion injury in mice.
Hepatology (Baltimore, Md.) 2008;47(1):215-24.
2007: Joseph S Solomkin; Chad T Robinson; Cynthia M Cave; Birgit Ehmer; Alex B Lentsch
Alterations in membrane cholesterol cause mobilization of lipid rafts from specific granules and prime human neutrophils for enhanced adherence-dependent oxidant production.
Shock (Augusta, Ga.) 2007;28(3):334-8.
2007: Charles C Caldwell; Johannes Tschoep; Alex B Lentsch
Lymphocyte function during hepatic ischemia/reperfusion injury.
Journal of leukocyte biology 2007;82(3):457-64.
2007: Jack T Saari; Loren E Wold; Jinhong Duan; Jun Ren; Hanqian L Carlson; Ann M Bode; Alex B Lentsch; Huawei Zeng; Dale A Schuschke
Cardiac nitric oxide synthases are elevated in dietary copper deficiency.
The Journal of nutritional biochemistry 2007;18(7):443-8.
2007: Satoshi Kuboki; Rebecca Schuster; John Blanchard; Timothy A Pritts; Hector R Wong; Alex B Lentsch
Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G1141-9.
2007: Alex B Lentsch; Peterson Pathrose; Sarah A Kader; Satoshi Kuboki; Margaret H Collins; Susan E Waltz
The Ron receptor tyrosine kinase regulates acute lung injury and suppresses nuclear factor kappaB activation.
Shock (Augusta, Ga.) 2007;27(3):274-80.
2007: Manfred Thiel; Charles C Caldwell; Simone Kreth; Satoshi Kuboki; P Chen; Patrick Smith; Akio Ohta; Alex B Lentsch; Dmitriy Lukashev; Michail V Sitkovsky
Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival.
PloS one 2007;2(9):e853.
2007: Satoshi Kuboki; Tomohisa Okaya; Rebecca Schuster; John Blanchard; Alvin Denenberg; Hector R Wong; Alex B Lentsch
Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G201-7.
2006: Hui Shen; Rebecca Schuster; Bao Lu; Susan E Waltz; Alex B Lentsch
Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth.
The Prostate 2006;66(16):1721-8.
2006: Alex B Lentsch
CXC chemokines and prostate cancer: growth regulators and potential biomarkers.
Future oncology (London, England) 2006;2(5):651-8.
2006: Luis H Toledo-Pereyra; Fernando Lopez-Neblina; Alex B Lentsch; Roberto Anaya-Prado; Suzanne J Romano; Peter A Ward
Selectin inhibition modulates NF-kappa B and AP-1 signaling after liver ischemia/reperfusion.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2006;19(5):313-22.
2006: Thomas L Husted; John Blanchard; Rebecca Schuster; H Shen; Alex B Lentsch
Potential role for IL-23 in hepatic ischemia/reperfusion injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006;55(5):177-8.
2006: Joseph S Solomkin; Chad T Robinson; Cynthia M Cave; Konstantin Umanskiy; Karl S Matlin; Mark A Williams; Alex B Lentsch
Formation of focal adhesion-like structures in circulating human neutrophils after severe injury: triggering of a tissue-phase response in the vascular space.
Shock (Augusta, Ga.) 2006;25(5):440-5.
2006: Thomas L Husted; Alex B Lentsch
The role of cytokines in pharmacological modulation of hepatic ischemia/reperfusion injury.
Current pharmaceutical design 2006;12(23):2867-73.
2006: Hui Shen; Rebecca Schuster; Keith F Stringer; Susan E Waltz; Alex B Lentsch
The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):59-64.
2006: Ali Mallakin; Louis W Kutcher; Susan A McDowell; Sue Kong; Rebecca Schuster; Alex B Lentsch; Bruce Aronow; George Leikauf; Susan E Waltz
Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury.
American journal of respiratory cell and molecular biology 2006;34(1):15-27.
2005: Charuhas V Thakar; Kamyar Zahedi; Monica P Revelo; Zhaohui Wang; Charles E Burnham; Sharon Barone; Shannon Bevans; Alex B Lentsch; Hamid Rabb; Manoocher Soleimani
Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia.
The Journal of clinical investigation 2005;115(12):3451-9.
2005: Tomohisa Okaya; John Blanchard; Rebecca Schuster; Satoshi Kuboki; Thomas L Husted; Charles C Caldwell; Basilia Zingarelli; Hector Wong; Joseph S Solomkin; Alex B Lentsch
Age-dependent responses to hepatic ischemia/reperfusion injury.
Shock (Augusta, Ga.) 2005;24(5):421-7.
2005: Charles C Caldwell; Tomohisa Okaya; Andre Martignoni; Thomas L Husted; Rebecca Schuster; Alex B Lentsch
Divergent functions of CD4+ T lymphocytes in acute liver inflammation and injury after ischemia-reperfusion.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G969-76.
2005: Sharon Barone; Tomohisa Okaya; Steven M Rudich; Snezana Petrovic; Kathy Tenrani; Zhaohui Wang; Kamyar Zahedi; Robert A Casero; Alex B Lentsch; Manoocher Soleimani
Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury.
American journal of physiology. Cell physiology 2005;289(4):C826-35.
2005: Sharon A Gordon; David Lominadze; Jack T Saari; Alex B Lentsch; Dale A Schuschke
Impaired deformability of copper-deficient neutrophils.
Experimental biology and medicine (Maywood, N.J.) 2005;230(8):543-8.
2005: Thomas L Husted; Meera Govindaswami; Peter R Oeltgen; Steven M Rudich; Alex B Lentsch
A delta2-opioid agonist inhibits p38 MAPK and suppresses activation of murine macrophages.
The Journal of surgical research 2005;128(1):45-9.
2005: Alex B Lentsch
Activation and function of hepatocyte NF-kappaB in postischemic liver injury.
Hepatology (Baltimore, Md.) 2005;42(1):216-8.
2005: Christopher N Mayhew; Emily E Bosco; Sejal R Fox; Tomohisa Okaya; Pheruza Tarapore; Sandy Schwemberger; George Babcock; Alex B Lentsch; Kenji Fukasawa; Erik S Knudsen
Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy.
Cancer research 2005;65(11):4568-77.
2005: Thomas L Husted; Alex B Lentsch
Anti-inflammatory approaches to the prevention of ischemia/reperfusion injury in solid organ transplantation.
Current opinion in investigational drugs (London, England : 2000) 2005;6(5):508-12.
2005: Tomohisa Okaya; Alex B Lentsch
Hepatic expression of S32A/S36A IkappaBalpha does not reduce postischemic liver injury.
The Journal of surgical research 2005;124(2):244-9.
2005: Mark A Williams; Cynthia M Cave; Gina Quaid; Chad Robinson; Thomas J Daly; Dan Witt; Alex B Lentsch; Joseph S Solomkin
Interleukin 8 dimerization as a mechanism for regulation of neutrophil adherence-dependent oxidant production.
Shock (Augusta, Ga.) 2005;23(4):371-6.
2004: Tomohisa Okaya; R Holthaus; Atsushi Kato; Alex B Lentsch
Involvement of the neuropeptide substance P in lung inflammation induced by hepatic ischemia/reperfusion.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53(6):257-61.
2004: Hui Shen; Alex B Lentsch
Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines.
American journal of physiology. Cell physiology 2004;286(4):C840-7.
2004: Tomohisa Okaya; Alex B Lentsch
Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(4):G606-12.
2003: Konstantin Umanskiy; Chad Robinson; Cynthia M Cave; Mark A Williams; Alex B Lentsch; Joseph Cuschieri; Joseph S Solomkin
NADPH oxidase activation in fibronectin adherent human neutrophils: A potential role for beta1 integrin ligation.
Surgery 2003;134(2):378-83.
2003: Tomohisa Okaya; Alex B Lentsch
Cytokine cascades and the hepatic inflammatory response to ischemia and reperfusion.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2003;16(3):141-7.
2003: Atsushi Kato; Tomohisa Okaya; Alex B Lentsch
Endogenous IL-13 protects hepatocytes and vascular endothelial cells during ischemia/reperfusion injury.
Hepatology (Baltimore, Md.) 2003;37(2):304-12.
2002: Dale A Schuschke; Susan S Percival; David Lominadze; Jack T Saari; Alex B Lentsch
Tissue-specific ICAM-1 expression and neutrophil transmigration in the copper-deficient rat.
Inflammation 2002;26(6):297-303.
2002: Atsushi Kato; Cem Gabay; Tomohisa Okaya; Alex B Lentsch
Specific role of interleukin-1 in hepatic neutrophil recruitment after ischemia/reperfusion.
The American journal of pathology 2002;161(5):1797-803.
2002: Ren-Feng Guo; Alex B Lentsch; J Vidya Sarma; Lei Sun; Niels C Riedemann; Shannon D McClintock; Stephanie R McGuire; Nico van Rooijen; Peter A Ward
Activator protein-1 activation in acute lung injury.
The American journal of pathology 2002;161(1):275-82.
2002: Alex B Lentsch
The Duffy antigen/receptor for chemokines (DARC) and prostate cancer. A role as clear as black and white?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(9):1093-5.
2002: Atsushi Kato; Michael J Edwards; Alex B Lentsch
Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion.
Journal of hepatology 2002;37(1):48-55.
2002: Roberto Anaya-Prado; Luis H Toledo-Pereyra; Alex B Lentsch; Peter A Ward
Ischemia/reperfusion injury.
The Journal of surgical research 2002;105(2):248-58.
2002: Peter A Ward; Alex B Lentsch
Endogenous regulation of the acute inflammatory response.
Molecular and cellular biochemistry 2002;234-235(1-2):225-8.
2002: Atsushi Kato; Amanda Graul-Layman; Michael J Edwards; Alex B Lentsch
Promotion of hepatic ischemia/reperfusion injury by IL-12 is independent of STAT4.
Transplantation 2002;73(7):1142-5.
2002: Atsushi Kato; Saurabh Singh; Kenneth R McLeish; Michael J Edwards; Alex B Lentsch
Mechanisms of hypothermic protection against ischemic liver injury in mice.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(4):G608-16.
2001: Alex B Lentsch; Atsushi Kato; B Davis; W Wang; C Chao; Michael J Edwards
STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia.
The Journal of clinical investigation 2001;108(10):1475-82.
2001: Christopher J Godshall; Alex B Lentsch; James C Peyton; Melanie J Scott; William G Cheadle
STAT4 is required for antibacterial defense but enhances mortality during polymicrobial sepsis.
Clinical and diagnostic laboratory immunology 2001;8(6):1044-8.
2001: Alex B Lentsch; Peter A Ward
Regulation of experimental lung inflammation.
Respiration physiology 2001;128(1):17-22.
2001: Alex B Lentsch; A Kato; Jack T Saari; Dale A Schuschke
Augmented metalloproteinase activity and acute lung injury in copper-deficient rats.
American journal of physiology. Lung cellular and molecular physiology 2001;281(2):L387-93.
2001: Ren-Feng Guo; Alex B Lentsch; Roscoe L Warner; Markus Huber-Lang; J Vidya Sarma; T Hlaing; MM Shi; Nicholas W Lukacs; Peter A Ward
Regulatory effects of eotaxin on acute lung inflammatory injury.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):5208-18.
2000: Alex B Lentsch; Atsushi Kato; H Yoshidome; K M McMasters; Michael J Edwards
Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury.
Hepatology (Baltimore, Md.) 2000;32(2):169-73.
2000: Atsushi Kato; H Yoshidome; Michael J Edwards; Alex B Lentsch
Regulation of liver inflammatory injury by signal transducer and activator of transcription-6.
The American journal of pathology 2000;157(1):297-302.
2000: Atsushi Kato; H Yoshidome; Michael J Edwards; Alex B Lentsch
Reduced hepatic ischemia/reperfusion injury by IL-4: potential anti-inflammatory role of STAT6.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(6):275-9.
2000: Michael S Mulligan; Alex B Lentsch; Markus Huber-Lang; Ren-Feng Guo; J Vidya Sarma; C D Wright; TR Ulich; Peter A Ward
Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor.
The American journal of pathology 2000;156(3):1033-9.
2000: NM Bless; Markus Huber-Lang; Ren-Feng Guo; Roscoe L Warner; Hagen Schmal; BJ Czermak; Thomas P Shanley; LD Crouch; Alex B Lentsch; J Vidya Sarma; Michael S Mulligan; HP Friedl; Peter A Ward
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2650-9.
2000: Alex B Lentsch; Peter A Ward
Regulation of inflammatory vascular damage.
The Journal of pathology 2000;190(3):343-8.
2000: Alex B Lentsch; Peter A Ward
The NFkappaBb/IkappaB system in acute inflammation.
Archivum immunologiae et therapiae experimentalis 2000;48(2):59-63.
1999: Alex B Lentsch; H Yoshidome; Atsushi Kato; Roscoe L Warner; William G Cheadle; Peter A Ward; Michael J Edwards
Requirement for interleukin-12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice.
Hepatology (Baltimore, Md.) 1999;30(6):1448-53.
1999: H Yoshidome; Atsushi Kato; Michael J Edwards; Alex B Lentsch
Interleukin-10 inhibits pulmonary NF-kappaB activation and lung injury induced by hepatic ischemia-reperfusion.
The American journal of physiology 1999;277(5 Pt 1):L919-23.
1999: H Yoshidome; Atsushi Kato; M Miyazaki; Michael J Edwards; Alex B Lentsch
IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion.
The American journal of pathology 1999;155(4):1059-64.
1999: Alex B Lentsch; H Yoshidome; Roscoe L Warner; Peter A Ward; Michael J Edwards
Secretory leukocyte protease inhibitor in mice regulates local and remote organ inflammatory injury induced by hepatic ischemia/reperfusion.
Gastroenterology 1999;117(4):953-61.
1999: Alex B Lentsch; LD Crouch; JA Jordan; BJ Czermak; E C Yun; R Guo; J Vidya Sarma; Kathleen M Diehl; Peter A Ward
Regulatory effects of interleukin-11 during acute lung inflammatory injury.
Journal of leukocyte biology 1999;66(1):151-7.
1999: H Yoshidome; Atsushi Kato; Michael J Edwards; Alex B Lentsch
Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB.
Hepatology (Baltimore, Md.) 1999;30(1):203-8.
1999: BJ Czermak; Alex B Lentsch; NM Bless; Hagen Schmal; HP Friedl; Peter A Ward
Synergistic enhancement of chemokine generation and lung injury by C5a or the membrane attack complex of complement.
The American journal of pathology 1999;154(5):1513-24.
1999: Alex B Lentsch; BJ Czermak; NM Bless; N Van Rooijen; Peter A Ward
Essential role of alveolar macrophages in intrapulmonary activation of NF-kappaB.
American journal of respiratory cell and molecular biology 1999;20(4):692-8.
1999: Alex B Lentsch; Peter A Ward
Activation and regulation of NFkappaB during acute inflammation.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1999;37(3):205-8.
1999: Alex B Lentsch; BJ Czermak; JA Jordan; Peter A Ward
Regulation of acute lung inflammatory injury by endogenous IL-13.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1071-6.
1999: Alex B Lentsch; Frederick N Miller; Michael J Edwards
Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2.
Cancer immunology, immunotherapy : CII 1999;47(5):243-8.
1999: Alex B Lentsch; JA Jordan; BJ Czermak; Kathleen M Diehl; Ellen M Younkin; J Vidya Sarma; Peter A Ward
Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation.
The American journal of pathology 1999;154(1):239-47.
1999: H Yoshidome; Alex B Lentsch; William G Cheadle; Frederick N Miller; Michael J Edwards
Enhanced pulmonary expression of CXC chemokines during hepatic ischemia/reperfusion-induced lung injury in mice.
The Journal of surgical research 1999;81(1):33-7.
1999: NM Bless; Roscoe L Warner; V A Padgaonkar; Alex B Lentsch; BJ Czermak; Hagen Schmal; HP Friedl; Peter A Ward
Roles for C-X-C chemokines and C5a in lung injury after hindlimb ischemia-reperfusion.
The American journal of physiology 1999;276(1 Pt 1):L57-63.
1998: NM Bless; S J Tojo; H Kawarai; Y Natsume; Alex B Lentsch; V A Padgaonkar; BJ Czermak; Hagen Schmal; HP Friedl; Peter A Ward
Differing patterns of P-selectin expression in lung injury.
The American journal of pathology 1998;153(4):1113-22.
1998: Hagen Schmal; BJ Czermak; Alex B Lentsch; NM Bless; Beatrice Beck-Schimmer; HP Friedl; Peter A Ward
Soluble ICAM-1 activates lung macrophages and enhances lung injury.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3685-93.
1998: Michael S Mulligan; Alex B Lentsch; Thomas P Shanley; M Miyasaka; Kent J Johnson; Peter A Ward
Cytokine and adhesion molecule requirements for lung injury induced by anti-glomerular basement membrane antibody.
Inflammation 1998;22(4):403-17.
1998: BJ Czermak; Alex B Lentsch; NM Bless; Hagen Schmal; HP Friedl; Peter A Ward
Role of complement in in vitro and in vivo lung inflammatory reactions.
Journal of leukocyte biology 1998;64(1):40-8.
1998: Michael S Mulligan; Alex B Lentsch; M Miyasaka; Peter A Ward
Cytokine and adhesion molecule requirements for neutrophil recruitment during glycogen-induced peritonitis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1998;47(6):251-5.
1998: Michael S Mulligan; Alex B Lentsch; Peter A Ward
In vivo recruitment of neutrophils: consistent requirements for L-arginine and variable requirements for complement and adhesion molecules.
Inflammation 1998;22(3):327-39.
1998: Alex B Lentsch; BJ Czermak; NM Bless; Peter A Ward
NF-kappaB activation during IgG immune complex-induced lung injury: requirements for TNF-alpha and IL-1beta but not complement.
The American journal of pathology 1998;152(5):1327-36.
1998: Alex B Lentsch; H Yoshidome; William G Cheadle; Frederick N Miller; Michael J Edwards
Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and KC.
Hepatology (Baltimore, Md.) 1998;27(4):1172-7.
1998: Alex B Lentsch; H Yoshidome; William G Cheadle; Frederick N Miller; Michael J Edwards
Chemokine involvement in hepatic ischemia/reperfusion injury in mice: roles for macrophage inflammatory protein-2 and Kupffer cells.
Hepatology (Baltimore, Md.) 1998;27(2):507-12.
1998: Alex B Lentsch; Michael J Edwards; D E Sims; Frederick N Miller
N omega-nitro-L-arginine methyl ester inhibits inflammatory liver injury induced by interleukin-2.
Journal of leukocyte biology 1998;63(1):22-30.
1997: Alex B Lentsch; Thomas P Shanley; J Vidya Sarma; Peter A Ward
In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.
The Journal of clinical investigation 1997;100(10):2443-8.
1997: Alex B Lentsch; Frederick N Miller; Michael J Edwards
Interleukin-2-induced hepatic injury involves temporal patterns of cell adhesion in the microcirculation.
The American journal of physiology 1997;272(4 Pt 1):G727-31.
1997: Alex B Lentsch; K Nakagawa; H Yoshidome; A Gerassimides; Frederick N Miller; Michael J Edwards
Distinct biological activities of recombinant forms of human interleukin-2 in vivo.
Cancer immunology, immunotherapy : CII 1997;43(6):331-6.
1996: Alex B Lentsch; Michael J Edwards; Frederick N Miller
Interleukin-2 induces increased platelet-endothelium interactions: a potential mechanism of toxicity.
The Journal of laboratory and clinical medicine 1996;128(1):75-82.
1996: Alex B Lentsch; Michael J Edwards; D E Sims; K Nakagawa; S R Wellhausen; Frederick N Miller
Interleukin-10 inhibits interleukin-2-induced tumor necrosis factor production but does not reduce toxicity in C3H/HeN mice.
Journal of leukocyte biology 1996;60(1):51-7.
1996: M J Edwards; DR Gable; Alex B Lentsch; J David Richardson
The rationale for esophagectomy as the optimal therapy for Barrett's esophagus with high-grade dysplasia.
Annals of surgery 1996;223(5):585-9; discussion 589-91.
1996: J A Anderson; Alex B Lentsch; D J Hadjiminas; Frederick N Miller; Alvin W Martin; K Nakagawa; Michael J Edwards
The role of cytokines, adhesion molecules, and chemokines in interleukin-2-induced lymphocytic infiltration in C57BL/6 mice.
The Journal of clinical investigation 1996;97(8):1952-9.
1996: K Nakagawa; Frederick N Miller; D E Sims; Alex B Lentsch; M Miyazaki; Michael J Edwards
Mechanisms of interleukin-2-induced hepatic toxicity.
Cancer research 1996;56(3):507-10.
1994: R A Lindberg; Dick W Slaaf; Alex B Lentsch; Frederick N Miller
Involvement of nitric oxide and cyclooxygenase products in photoactivation-induced microvascular occlusion.
Microvascular research 1994;47(2):203-21.