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Giuseppina Leo

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TOP 3
Enrica Baldelli; Giuseppina Leo; Norma Andreoli; Kjell Fuxe; Giuseppe Biagini; Luigi F Agnati
Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment.
L F Agnati; Diego Guidolin; F Baluska; Giuseppina Leo; P W Barlow; C Carone; Susanna Genedani
A new hypothesis of pathogenesis based on the divorce between mitochondria and their host cells: possible relevance for Alzheimer's disease.
Susanna Genedani; Luigi F Agnati; Giuseppina Leo; D Buzzega; Francesca Maccari; C Carone; Norma Andreoli; Monica Filaferro; Nicola Volpi
beta-Amyloid fibrillation and/or hyperhomocysteinemia modify striatal patterns of hyaluronic acid and dermatan sulfate: Possible role in the pathogenesis of Alzheimer's disease.

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All Publications

2010: Enrica Baldelli; Giuseppina Leo; Norma Andreoli; Kjell Fuxe; Giuseppe Biagini; Luigi F Agnati
Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment.
Neuromolecular medicine 2010;12(3):248-59.
2010: L F Agnati; Diego Guidolin; F Baluska; Giuseppina Leo; P W Barlow; C Carone; Susanna Genedani
A new hypothesis of pathogenesis based on the divorce between mitochondria and their host cells: possible relevance for Alzheimer's disease.
Current Alzheimer research 2010;7(4):307-22.
2010: Susanna Genedani; Luigi F Agnati; Giuseppina Leo; D Buzzega; Francesca Maccari; C Carone; Norma Andreoli; Monica Filaferro; Nicola Volpi
beta-Amyloid fibrillation and/or hyperhomocysteinemia modify striatal patterns of hyaluronic acid and dermatan sulfate: Possible role in the pathogenesis of Alzheimer's disease.
Current Alzheimer research 2010;7(2):150-7.
2010: Luigi F Agnati; Diego Guidolin; Giuseppina Leo; Chiara Carone; Susanna Genedani; Kjell Fuxe
Receptor-receptor interactions: A novel concept in brain integration.
Progress in neurobiology 2010;90(2):157-75.
2010: Kjell Fuxe; Daniel Marcellino; Giuseppina Leo; Luigi F Agnati
Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis.
Current opinion in pharmacology 2010;10(1):14-22.
2009: Luigi F Agnati; Giuseppina Leo; Susanna Genedani; L Piron; A Rivera; Diego Guidolin; Kjell Fuxe
Common key-signals in learning and neurodegeneration: focus on excito-amino acids, beta-amyloid peptides and alpha-synuclein.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(8):953-74.
2008: Luigi F Agnati; Giuseppina Leo; Susanna Genedani; N Andreoli; D Marcellino; Amina S Woods; L Piron; Diego Guidolin; Kjell Fuxe
Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains.
Brain research reviews 2008;58(2):459-74.
2008: Jose A Aguirre; Giuseppina Leo; Raquel Cueto; Beth Andbjer; Alan Naylor; Andrew D Medhurst; Luigi F Agnati; Kjell Fuxe
The novel cyclooxygenase-2 inhibitor GW637185X protects against l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
Neuroreport 2008;19(6):657-60.
2007: Alessio Zanardi; Rosaria Ferrari; Giuseppina Leo; Uwe Maskos; Jean-Pierre Changeux; Michele Zoli
Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4028-37.
2007: Luigi F Agnati; Diego Guidolin; Giuseppina Leo; Susanna Genedani; P Arhem; A Forni; Norma Andreoli; Kjell Fuxe
Role of cooperativity in protein folding and protein mosaic assemblage relevance for protein conformational diseases.
Current protein & peptide science 2007;8(5):460-70.
2007: Luigi F Agnati; Susanna Genedani; Giuseppina Leo; Alicia Rivera; Diego Guidolin; Kjell Fuxe
One century of progress in neuroscience founded on Golgi and Cajal's outstanding experimental and theoretical contributions.
Brain research reviews 2007;55(1):167-89.
2007: Kjell Fuxe; Annica Dahlström; Malin Höistad; Daniel Marcellino; Anders Jansson; Alicia Rivera; Zaida Diaz-Cabiale; Kirsten X Jacobsen; Barbro Tinner-Staines; Beth Hagman; Giuseppina Leo; William Staines; Diego Guidolin; Julia Kehr; Susanna Genedani; Natale Belluardo; Luigi F Agnati
From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission.
Brain research reviews 2007;55(1):17-54.
2007: Giuseppina Leo; Susanna Genedani; Monica Filaferro; Chiara Carone; Norma Andreoli; Serenella Astancolle; Pierpaola Davalli; Kjell Fuxe; Luigi F Agnati
Hyper-homocysteinemia alters amyloid peptide-clusterin interactions and neuroglial network morphology and function in the caudate after intrastriatal injection of amyloid peptides.
Current Alzheimer research 2007;4(3):305-13.
2007: Luigi F Agnati; Giuseppina Leo; Susanna Genedani; Diego Guidolin; Norma Andreoli; Kjell Fuxe
Possible relevance of receptor-receptor interactions between viral- and host-coded receptors for viral-induced disease.
TheScientificWorldJournal 2007;7():1073-81.
2007: Kjell Fuxe; Meritxell Canals; Maria Torvinen; Daniel Marcellino; Anton Terasmaa; Susanna Genedani; Giuseppina Leo; Diego Guidolin; Zaida Diaz-Cabiale; A Rivera; L Lundstrom; U Langel; Jose Narvaez; S Tanganelli; Carmen Lluis; Sergi Ferré; Amina S Woods; Rafael Franco; Luigi F Agnati
Intramembrane receptor-receptor interactions: a novel principle in molecular medicine.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(1):49-75.
2007: Luigi F Agnati; Susanna Genedani; Giuseppina Leo; A Forni; Amina S Woods; Monica Filaferro; Rafael Franco; Kjell Fuxe
Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(1):21-31.
2007: Luigi F Agnati; Diego Guidolin; Giuseppina Leo; Kjell Fuxe
A boolean network modelling of receptor mosaics relevance of topology and cooperativity.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(1):77-92.
2006: Luigi F Agnati; Sergi Ferré; Susanna Genedani; Giuseppina Leo; Diego Guidolin; Monica Filaferro; Paulina Carriba; Vicent Casadó; Carmen Lluis; Rafael Franco; Amina S Woods; Kjell Fuxe
Allosteric modulation of dopamine D2 receptors by homocysteine.
Journal of proteome research 2006;5(11):3077-83.
2006: Luigi F Agnati; Giuseppina Leo; Alessio Zanardi; Susanna Genedani; A Rivera; Kjell Fuxe; Diego Guidolin
Volume transmission and wiring transmission from cellular to molecular networks: history and perspectives.
Acta physiologica (Oxford, England) 2006;187(1-2):329-44.
2005: Luigi F Agnati; Kjell Fuxe; Maria Torvinen; Susanna Genedani; Rafael Franco; Stanley J Watson Jr; Gastone G Nussdorfer; Giuseppina Leo; Diego Guidolin
New methods to evaluate colocalization of fluorophores in immunocytochemical preparations as exemplified by a study on A2A and D2 receptors in Chinese hamster ovary cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(8):941-53.
2005: Jose A Aguirre; Julia Kehr; Takashi Yoshitake; Fang-Ling Liu; Alicia Rivera; Sergio Fernandez-Espinola; Beth Andbjer; Giuseppina Leo; Andrew D Medhurst; Luigi F Agnati; Kjell Fuxe
Protection but maintained dysfunction of nigral dopaminergic nerve cell bodies and striatal dopaminergic terminals in MPTP-lesioned mice after acute treatment with the mGluR5 antagonist MPEP.
Brain research 2005;1033(2):216-20.
2005: Susanna Genedani; Diego Guidolin; Giuseppina Leo; Monica Filaferro; Maria Torvinen; Amina S Woods; Kjell Fuxe; Sergi Ferré; Luigi F Agnati
Computer-assisted image analysis of caveolin-1 involvement in the internalization process of adenosine A2A-dopamine D2 receptor heterodimers.
Journal of molecular neuroscience : MN 2005;26(2-3):177-84.
2005: Kjell Fuxe; A Rivera; Kirsten X Jacobsen; Malin Höistad; Giuseppina Leo; T L Horvath; William Staines; A De la Calle; Luigi F Agnati
Dynamics of volume transmission in the brain. Focus on catecholamine and opioid peptide communication and the role of uncoupling protein 2.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(1):65-76.
2005: Luigi F Agnati; Susanna Genedani; P L Lenzi; Giuseppina Leo; F Mora; Sergi Ferré; Kjell Fuxe
Energy gradients for the homeostatic control of brain ECF composition and for VT signal migration: introduction of the tide hypothesis.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(1):45-63.
2004: Luigi F Agnati; Giuseppina Leo; Anna Valeria Vergoni; Emili Martínez; Jörg Hockemeyer; Carmen Lluis; Rafael Franco; Kjell Fuxe; Sergi Ferré
Neuroprotective effect of L-DOPA co-administered with the adenosine A2A receptor agonist CGS 21680 in an animal model of Parkinson's disease.
Brain research bulletin 2004;64(2):155-64.
2004: Luigi F Agnati; Sergi Ferré; Giuseppina Leo; Carmen Lluis; Enric Isidre Canela; Rafael Franco; Kjell Fuxe
On the molecular basis of the receptor mosaic hypothesis of the engram.
Cellular and molecular neurobiology 2004;24(4):501-16.
2004: Fang-Ling Liu; Kjell Fuxe; Natale Belluardo; Giuseppina Leo; Luigi F Agnati; Jose A Aguirre
Acute intermittent nicotine treatment produces a reduction in the total number of FGF-2 immunoreactive astroglial cells in the substantia nigra of the rat: a stereological analysis.
Neuroscience letters 2004;355(3):181-4.
2004: Luigi F Agnati; Anna Valeria Vergoni; Giuseppina Leo; Susanna Genedani; Rafael Franco; Alfio Bertolini; Kjell Fuxe
Energy gradients for VT-signal migration in the CNS: studies on melanocortin receptors, mitochondrial uncoupling proteins and food intake.
Journal of endocrinological investigation 2004;27(6 Suppl):23-34.
2003: Kjell Fuxe; Luigi F Agnati; Kirsten X Jacobsen; Joelle Hillion; Meritxell Canals; Maria Torvinen; B Tinner-Staines; William Staines; D Rosin; Anton Terasmaa; Patrizia Popoli; Giuseppina Leo; V Vergoni; Carmen Lluis; Francisco Ciruela; Rafael Franco; Sergi Ferré
Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinson's disease.
Neurology 2003;61(11 Suppl 6):S19-23.
2003: Antonio Torsello; Barbara Scibona; Giuseppina Leo; Elena Bresciani; Roberta Avallone; Ilaria Bulgarelli; Marina Luoni; Michele Zoli; Guido Rindi; Daniela Cocchi; Vittorio Locatelli
Ontogeny and tissue-specific regulation of ghrelin mRNA expression suggest that ghrelin is primarily involved in the control of extraendocrine functions in the rat.
Neuroendocrinology 2003;77(2):91-9.
2002: Carla Torri; Patrizia Pedrazzi; Giuseppina Leo; Eugenio E Müller; Daniela Cocchi; Luigi F Agnati; Michele Zoli
Diet-induced changes in hypothalamic pro-opio-melanocortin mRNA in the rat hypothalamus.
Peptides 2002;23(6):1063-8.
2002: Augusta Benelli; Alfio Bertolini; Michele Zoli; Giuseppina Leo; Monica Filaferro; Sabrina Saltini; Susanna Genedani
Pharmacological manipulation of brain galaninergic system and sexual behavior in male mice.
Psychopharmacology 2002;160(3):325-30.
2002: Alessio Zanardi; Giuseppina Leo; Giuseppe Biagini; Michele Zoli
Nicotine and neurodegeneration in ageing.
Toxicology letters 2002;127(1-3):207-15.
1999: R Ferrari; A Frasoldati; Giuseppina Leo; Carla Torri; Isabella Zini; Luigi F Agnati; Michele Zoli
Changes in nicotinic acetylcholine receptor subunit mRNAs and nicotinic binding in spontaneously hypertensive stroke prone rats.
Neuroscience letters 1999;277(3):169-72.