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Doreen Lepage

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Louise A Koopman Van Aarsen; Diane R Leone; Steffan Ho; Brian M Dolinski; Patricia E McCoon; Doreen J Lepage; Rebecca Kelly; Glenna Heaney; Paul Rayhorn; Carl Reid; Kenneth J Simon; Gerald S Horan; Nianjun Tao; Humphrey A Gardner; Marilyn M Skelly; Allen M Gown; Gareth J Thomas; Paul H Weinreb; SE Fawell; Shelia M Violette
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
R Blake Pepinsky; Wen-Cherng Lee; Mark Cornebise; Alan Gill; K Wortham; Ling Ling Chen; Diane R Leone; Keith Giza; Brian M Dolinski; Stuart J Perper; Cheryl Nickerson-Nutter; Doreen J Lepage; Abhijit Chakraborty; Eric T Whalley; Russell C Petter; Steven P Adams; Roy R Lobb; Daniel M Scott
Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
Heather B Adkins; Caterina Bianco; Susan G Schiffer; Paul Rayhorn; Mohammad Zafari; Anne E Cheung; Olivia Orozco; Dian Olson; Antonella De Luca; Ling Ling Chen; Konrad Miatkowski; Christopher D Benjamin; Nicola Normanno; Kevin P Williams; Matthew Jarpe; Doreen J Lepage; David Salomon; Michele Sanicola
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.

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All Publications

2008: Louise A Koopman Van Aarsen; Diane R Leone; Steffan Ho; Brian M Dolinski; Patricia E McCoon; Doreen J Lepage; Rebecca Kelly; Glenna Heaney; Paul Rayhorn; Carl Reid; Kenneth J Simon; Gerald S Horan; Nianjun Tao; Humphrey A Gardner; Marilyn M Skelly; Allen M Gown; Gareth J Thomas; Paul H Weinreb; SE Fawell; Shelia M Violette
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
Cancer research 2008;68(2):561-70.
2005: R Blake Pepinsky; Wen-Cherng Lee; Mark Cornebise; Alan Gill; K Wortham; Ling Ling Chen; Diane R Leone; Keith Giza; Brian M Dolinski; Stuart J Perper; Cheryl Nickerson-Nutter; Doreen J Lepage; Abhijit Chakraborty; Eric T Whalley; Russell C Petter; Steven P Adams; Roy R Lobb; Daniel M Scott
Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
The Journal of pharmacology and experimental therapeutics 2005;312(2):742-50.
2003: Heather B Adkins; Caterina Bianco; Susan G Schiffer; Paul Rayhorn; Mohammad Zafari; Anne E Cheung; Olivia Orozco; Dian Olson; Antonella De Luca; Ling Ling Chen; Konrad Miatkowski; Christopher D Benjamin; Nicola Normanno; Kevin P Williams; Matthew Jarpe; Doreen J Lepage; David Salomon; Michele Sanicola
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
The Journal of clinical investigation 2003;112(4):575-87.
2003: Diane R Leone; Keith Giza; Alan Gill; Brian M Dolinski; W Yang; Stuart J Perper; Daniel M Scott; Wen-Cherng Lee; Mark Cornebise; K Wortham; Cheryl Nickerson-Nutter; Ling Ling Chen; Doreen J Lepage; J C Spell; Eric T Whalley; Russell C Petter; Steven P Adams; Roy R Lobb; R Blake Pepinsky
An assessment of the mechanistic differences between two integrin alpha 4 beta 1 inhibitors, the monoclonal antibody TA-2 and the small molecule BIO5192, in rat experimental autoimmune encephalomyelitis.
The Journal of pharmacology and experimental therapeutics 2003;305(3):1150-62.
2002: R Blake Pepinsky; Renee I Shapiro; Shaoshan Wang; Abhijit Chakraborty; Alan Gill; Doreen J Lepage; Dingyi Wen; Paul Rayhorn; Gerald S B Horan; Frederick R Taylor; Ellen A Garber; Alphonse Galdes; Thomas Engber
Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model.
Journal of pharmaceutical sciences 2002;91(2):371-87.
2001: R Blake Pepinsky; Doreen J Lepage; Alan Gill; Abhijit Chakraborty; S Vaidyanathan; M Green; Darren P Baker; Eric T Whalley; Paula S Hochman; P Martin
Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferon-beta-1a with preserved in vitro bioactivity.
The Journal of pharmacology and experimental therapeutics 2001;297(3):1059-66.