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Sophie Lepage

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Publications

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Valérie Duval; Marc Swinnen; Sophie Lepage; Alain Brans; Benoît Granier; Christine Franssen; Jean-Marie Frère; Bernard Joris
The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis.
Bernard Lakaye; Alain Dubus; Sophie Lepage; Sylvie Groslambert; Jean-Marie Frère
When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams.
G H Zhao; Colette Duez; Sophie Lepage; C Forceille; Noureddine Rhazi; D Klein; Jean-Marie Ghuysen; Jean-Marie Frère
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.

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All Publications

2003: Valérie Duval; Marc Swinnen; Sophie Lepage; Alain Brans; Benoît Granier; Christine Franssen; Jean-Marie Frère; Bernard Joris
The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis.
Molecular microbiology 2003;48(6):1553-64.
1999: Bernard Lakaye; Alain Dubus; Sophie Lepage; Sylvie Groslambert; Jean-Marie Frère
When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams.
Molecular microbiology 1999;31(1):89-101.
1997: G H Zhao; Colette Duez; Sophie Lepage; C Forceille; Noureddine Rhazi; D Klein; Jean-Marie Ghuysen; Jean-Marie Frère
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.
The Biochemical journal 1997;327 ( Pt 2)():377-81.
1997: Sophie Lepage; P Dubois; Tushar Ghosh; Bernard Joris; S Mahapatra; M Kundu; J Basu; P Chakrabarti; S T Cole; Martine Nguyen-Distèche; Jean-Marie Ghuysen
Dual multimodular class A penicillin-binding proteins in Mycobacterium leprae.
Journal of bacteriology 1997;179(14):4627-30.
1997: Karin Hardt; Bernard Joris; Sophie Lepage; Robert Brasseur; J O Lampen; Jean-Marie Frère; Anthony L Fink; Jean-Marie Ghuysen
The penicillin sensory transducer, BlaR, involved in the inducibility of beta-lactamase synthesis in Bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle.
Molecular microbiology 1997;23(5):935-44.
1995: Sophie Lepage; Moreno Galleni; Bernard Lakaye; Bernard Joris; Iris Thamm; Jean-Marie Frere
Kinetic properties of the Bacillus licheniformis penicillin-binding proteins.
The Biochemical journal 1995;309 ( Pt 1)():49-53.
1995: Sophie Lepage; Bernard Lakaye; Moreno Galleni; Iris Thamm; M Crine; S Groslambert; Jean-Marie Frère
Saturation of penicillin-binding protein 1 by beta-lactam antibiotics in growing cells of Bacillus licheniformis.
Molecular microbiology 1995;16(2):365-72.
1994: Bernard Lakaye; C Damblon; M Jamin; Moreno Galleni; Sophie Lepage; Bernard Joris; Jacqueline Marchand-Brynaert; C Frydrych; Jean-Marie Frere
Synthesis, purification and kinetic properties of fluorescein-labelled penicillins.
The Biochemical journal 1994;300 ( Pt 1)():141-5.
1993: Moreno Galleni; Bernard Lakaye; Sophie Lepage; M Jamin; Iris Thamm; Bernard Joris; Jean-Marie Frère
A new, highly sensitive method for the detection and quantification of penicillin-binding proteins.
The Biochemical journal 1993;291 ( Pt 1)():19-21.
1992: B Granier; Colette Duez; Sophie Lepage; S Englebert; Jean Dusart; Otto Dideberg; J Van Beeumen; Jean-Marie Frère; Jean-Marie Ghuysen
Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;286 ( Pt 3)():981-2.
1992: B Granier; Colette Duez; Sophie Lepage; S Englebert; Jean Dusart; Otto Dideberg; J Van Beeumen; Jean-Marie Frère; Jean-Marie Ghuysen
Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;282 ( Pt 3)():781-8.
1990: F Jacob; Bernard Joris; Sophie Lepage; Jean Dusart; Jean-Marie Frère
Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis.
The Biochemical journal 1990;271(2):399-406.