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Karen Leroy

Research Profile

Disorders

Physiology

Gene Expression Regulation, Neoplastic

Procedures

Chemicals & Drugs

Concepts & Ideas

Anatomy

Chromosomes, Human, Pair 18

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Publications

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Michaël Lévy; Iradj Sobhani; Aurélien Amiot; Yann Le Baleur; Karim Belhadj; Christiane Copie-Bergman; Marie-Hélène Delfau-Larue; Jehan Dupuis; Corinne Haioun; François Hémery; Karen Leroy; Jean-Charles Delchier
Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study.
Sandra Rebouissou; Audrey Riou; Mathilde Sibony; Dimitri Vordos; Yves Allory; Simone Benhamou; Alexandre de la Taille; Yves Denoux; Frédéric Guyon; Aurélie Hérault; Agnès Laplanche; Thierry Lebret; May-Linda Lepage; Karen Leroy; Eric Letouzé; Pascale Maillé; Yann Neuzillet; Karina Ofualuka; François Radvanyi
CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma.
Emilie Bessède; Christiane Copie-Bergman; Jean-Charles Delchier; Philippe Lehours; Karen Leroy; Michael Levy; Francis Mégraud; Audrey Riou; Maryse Baia; Nathalie Salles
Is elevated gastric tissue NOX2 associated with lymphoma of mucosa-associated lymphoid tissue?

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All Publications

2013: Michaël Lévy; Iradj Sobhani; Aurélien Amiot; Yann Le Baleur; Karim Belhadj; Christiane Copie-Bergman; Marie-Hélène Delfau-Larue; Jehan Dupuis; Corinne Haioun; François Hémery; Karen Leroy; Jean-Charles Delchier
Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study.
Leukemia & lymphoma 2013;54(5):940-4.
2012: Sandra Rebouissou; Audrey Riou; Mathilde Sibony; Dimitri Vordos; Yves Allory; Simone Benhamou; Alexandre de la Taille; Yves Denoux; Frédéric Guyon; Aurélie Hérault; Agnès Laplanche; Thierry Lebret; May-Linda Lepage; Karen Leroy; Eric Letouzé; Pascale Maillé; Yann Neuzillet; Karina Ofualuka; François Radvanyi
CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma.
The Journal of pathology 2012;227(3):315-24.
2012: Emilie Bessède; Christiane Copie-Bergman; Jean-Charles Delchier; Philippe Lehours; Karen Leroy; Michael Levy; Francis Mégraud; Audrey Riou; Maryse Baia; Nathalie Salles
Is elevated gastric tissue NOX2 associated with lymphoma of mucosa-associated lymphoid tissue?
Antioxidants & redox signaling 2012;16(11):1205-11.
2012: Yann Neuzillet; Slah Ouerhani; Xavier Paoletti; Audrey Renou; Mathilde Sibony; Hany Soliman; Dimitri Vordos; CC Abbou; Yves Allory; Bernard Asselain; Ashraf A Bakkar; Simone Benhamou; Hugues de The; Yves Denoux; Amel El Gaaied; Aurélie Herault; Nadia Kourda; Agnès Laplanche; Thierry Lebret; May-Linda Lepage; Karen Leroy; Pascale Maille; Vincent Molinie; Pierre Mongiat-Artus; François Radvanyi
A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer.
PloS one 2012;7(12):e48993.
2011: Amélie Carbonnelle-Puscian; Valérie Vidal; Ingrid Laurendeau; Laurence Valeyrie-Allanore; Dominique Vidaud; Ivan Bièche; Karen Leroy; Laurent A Lantieri; Pierre Wolkenstein; Andreas Schedl; Nicolas Ortonne
SOX9 expression increases with malignant potential in tumors from patients with neurofibromatosis 1 and is not correlated to desert hedgehog.
Human pathology 2011;42(3):434-43.
2011: Eric Pasmant; Julien Masliah-Planchon; Pascale Lévy; Ingrid Laurendeau; Nicolas Ortonne; Béatrice Parfait; Laurence Valeyrie-Allanore; Karen Leroy; Pierre Wolkenstein; Michel Vidaud; Dominique Vidaud; Ivan Bièche
Identification of genes potentially involved in the increased risk of malignancy in NF1-microdeleted patients.
Molecular medicine (Cambridge, Mass.) 2011;17(1-2):79-87.
2010: Michaël Lévy; Christiane Copie-Bergman; Valérie Molinier-Frenkel; Audrey Riou; Corinne Haioun; Philippe Gaulard; Marie-Hélène Delfau-Larue; Iradj Sobhani; Karen Leroy; Jean-Charles Delchier
Treatment of t(11;18)-positive gastric mucosa-associated lymphoid tissue lymphoma with rituximab and chlorambucil: clinical, histological, and molecular follow-up.
Leukemia & lymphoma 2010;51(2):284-90.
2010: Eric Pasmant; Nicolas Ortonne; Laure Rittie; Ingrid Laurendeau; Pascale Lévy; Vladimir Lazar; Béatrice Parfait; Karen Leroy; Philippe Dessen; Laurence Valeyrie-Allanore; Bernard Perbal; Pierre Wolkenstein; Michel Vidaud; Dominique Vidaud; Ivan Bièche
Differential expression of CCN1/CYR61, CCN3/NOV, CCN4/WISP1, and CCN5/WISP2 in neurofibromatosis type 1 tumorigenesis.
Journal of neuropathology and experimental neurology 2010;69(1):60-9.
2009: Christiane Copie-Bergman; Philippe Gaulard; Karen Leroy; Josette Briere; Maryse Baia; Jean-Philippe jais; Gilles A Salles; Françoise Berger; Corinne Haioun; Herve Tilly; Jean-François Emile; Alison H Banham; Nicolas Mounier; Christian Gisselbrecht; Pierre Feugier; Bertrand Coiffier; Thierry Molina
Immuno-fluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: a GELA study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(33):5573-9.
2008: Nijez Aloulou; Sylvie Bastuji-Garin; Sabine Le Gouvello; Mohammad Abolhassani; Marie-Thérèse Chaumette; Antoine Charachon; Karen Leroy; Iradj Sobhani
Involvement of the leptin receptor in the immune response in intestinal cancer.
Cancer research 2008;68(22):9413-22.
2008: Sabine Le Gouvello; S Bastuji-Garin; N Aloulou; H Mansour; Marie-Thérèse Chaumette; F Berrehar; A Seikour; Antoine Charachon; Mehdi Karoui; Karen Leroy; Jean-Pierre Farcet; Iradj Sobhani
High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas.
Gut 2008;57(6):772-9.
2008: Emmanuelle Boulanger; Véronique Meignin; Maryse Baia; Valérie Molinier-Frenkel; Karen Leroy; Eric Oksenhendler; Laurence Gérard; Christiane Copie-Bergman
Mucosa-associated lymphoid tissue lymphoma in patients with human immunodeficiency virus infection.
British journal of haematology 2008;140(4):470-4.
2008: Nicolas Ortonne; Sabine Le Gouvello; Hicham Mansour; Catherine Poillet; Nadine Martin; Marie-Hélène Delfau-Larue; Karen Leroy; Jean-Pierre Farcet; Martine Bagot; Armand Bensussan
CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome.
The Journal of investigative dermatology 2008;128(2):465-72.
2007: Marie-Laure Boulland; Jeanine Marquet; Valérie Molinier-Frenkel; Peter Möller; Chrystelle Guiter; Fanette Lasoudris; Christiane Copie-Bergman; Maryse Baia; Philippe Gaulard; Karen Leroy; Flavia Castellano
Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation.
Blood 2007;110(1):220-7.
2007: Laurence de Leval; David S Rickman; Caroline Thielen; Aurélien de Reynies; Y Huang; Georges Delsol; Laurence Lamant; Karen Leroy; Josette Brière; Thierry Molina; Françoise Berger; Christian Gisselbrecht; Luc Xerri; Philippe Gaulard
The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells.
Blood 2007;109(11):4952-63.
2007: Pascale Lévy; Hugues Ripoche; Ingrid Laurendeau; Vladimir Lazar; Nicolas Ortonne; Béatrice Parfait; Karen Leroy; Janine Wechsler; Isabelle Salmon; Pierre Wolkenstein; Philippe Dessen; Michel Vidaud; Dominique Vidaud; Ivan Bièche
Microarray-based identification of tenascin C and tenascin XB, genes possibly involved in tumorigenesis associated with neurofibromatosis type 1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 1):398-407.
2005: Michaël Lévy; Christiane Copie-Bergman; Christine Gameiro; Marie-Thérèse Chaumette; Marie-Hélène Delfau-Larue; Corinne Haioun; Antoine Charachon; François Hemery; Philippe Gaulard; Karen Leroy; Jean-Charles Delchier
Prognostic value of translocation t(11;18) in tumoral response of low-grade gastric lymphoma of mucosa-associated lymphoid tissue type to oral chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):5061-6.
2005: Christiane Copie-Bergman; C Locher; Michael Levy; Marie-Thérèse Chaumette; Corinne Haioun; Marie-Hélène Delfau-Larue; Karen Leroy; Philippe Gaulard; Jean-Charles Delchier
Metachronous gastric MALT lymphoma and early gastric cancer: is residual lymphoma a risk factor for the development of gastric carcinoma?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(8):1232-6.
2005: Nicolas Ortonne; Christiane Copie-Bergman; Philippe Remy; Marie-Hélène Delfau-Larue; Miguel A Alonso; Xavier Mariette; Judith Dierlamm; Karen Leroy; Philippe Gaulard
Mucosa-associated lymphoid tissue lymphoma of the thymus: a case report with no evidence of MALT1 rearrangement.
Virchows Archiv : an international journal of pathology 2005;446(2):189-93.
2004: Pascale Lévy; Dominique Vidaud; Karen Leroy; Ingrid Laurendeau; Janine Wechsler; Giulia Bolasco; Béatrice Parfait; Pierre Wolkenstein; Michel Vidaud; Ivan Bièche
Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR.
Molecular cancer 2004;3():20.
2004: Chrystelle Guiter; Isabelle Dusanter-Fourt; Christiane Copie-Bergman; Marie-Laure Boulland; Sabine Le Gouvello; Philippe Gaulard; Karen Leroy; Flavia Castellano
Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.
Blood 2004;104(2):543-9.
2004: Pascale Lévy; Ivan Bièche; Karen Leroy; Béatrice Parfait; Janine Wechsler; Ingrid Laurendeau; Pierre Wolkenstein; Michel Vidaud; Dominique Vidaud
Molecular profiles of neurofibromatosis type 1-associated plexiform neurofibromas: identification of a gene expression signature of poor prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3763-71.
2004: Catherine Thieblemont; Valéry Nasser; Pascale Felman; Karen Leroy; Sophie Gazzo; Evelyne Callet-Bauchu; Béatrice Loriod; Samuel Granjeaud; Philippe Gaulard; Corinne Haioun; Alexandra Traverse-Glehen; Lucile Baseggio; François Bertucci; Daniel Birnbaum; Florence Magrangeas; Stéphane Minvielle; Hervé Avet-Loiseau; Gilles SALLES; Bertrand Coiffier; Françoise Berger; Rémi Houlgatte
Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis.
Blood 2004;103(7):2727-37.
2003: Catherine Leroy-Matheron; Christophe Duvoux; Jeanne Tran Van Nhieu; Karen Leroy; Daniel Cherqui; Michèle Gouault-Heilmann
Activated protein C resistance acquired through liver transplantation and associated with recurrent venous thrombosis.
Journal of hepatology 2003;38(6):866-9.
2003: Ivan Bièche; Valérie Manceau; Patrick A Curmi; Ingrid Laurendeau; Sylvie Lachkar; Karen Leroy; Dominique Vidaud; André Sobel; Alexandre Maucuer
Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human.
Brain research. Molecular brain research 2003;114(1):55-64.
2003: Christiane Copie-Bergman; Marie-Laure Boulland; Catherine Dehoulle; Peter Möller; Jean-Pierre Farcet; Martin J S Dyer; Corinne Haioun; Paul-Henri Roméo; Philippe Gaulard; Karen Leroy
Interleukin 4-induced gene 1 is activated in primary mediastinal large B-cell lymphoma.
Blood 2003;101(7):2756-61.
2002: Christiane Copie-Bergman; Anne Plonquet; Miguel A Alonso; Marie-Laure Boulland; Jeanine Marquet; Marine Divine; Peter Möller; Karen Leroy; Philippe Gaulard
MAL expression in lymphoid cells: further evidence for MAL as a distinct molecular marker of primary mediastinal large B-cell lymphomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2002;15(11):1172-80.
2002: Karen Leroy; Corinne Haioun; Eric Lepage; N Le Métayer; F Berger; Eric Labouyrie; V Meignin; Barbara Petit; C Bastard; Gilles SALLES; Christian Gisselbrecht; Felix Reyes; Philippe Gaulard
p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(7):1108-15.
2001: Karen Leroy; V Dumas; Nadine Martin-Garcia; M C Falzone; Marie-Catherine Voisin; Janine Wechsler; Jean Revuz; Alain Créange; E Levy; Laurent A Lantieri; Jacques Zeller; Pierre Wolkenstein
Malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1: a clinicopathologic and molecular study of 17 patients.
Archives of dermatology 2001;137(7):908-13.
2001: Barbara Petit; Karen Leroy; Panagiotis Kanavaros; Marie-Laure Boulland; M Druet-Cabanac; Corinne Haioun; Dominique Bordessoule; Philippe Gaulard
Expression of p53 protein in T- and natural killer-cell lymphomas is associated with some clinicopathologic entities but rarely related to p53 mutations.
Human pathology 2001;32(2):196-204.
1999: Christiane Copie-Bergman; Philippe Gaulard; Leïla Maouche-Chrétien; Josette Brière; Corinne Haioun; Miguel A Alonso; Paul-Henri Roméo; Karen Leroy
The MAL gene is expressed in primary mediastinal large B-cell lymphoma.
Blood 1999;94(10):3567-75.