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Thierry Lesimple

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Véronique Quillien; Stephan Saikali; Marc Sanson; Michel Wager; Frédéric Fina; Jérome Honnorat; L Karayan-Tapon; Marianne Labussière; Audrey Lavenu; Thierry Lesimple; Catherine Carpentier; Olivier Chinot; Dominique Figarella-Branger
Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of 100 glioblastoma patients.
Elodie Vauleon; Odile Audrain; Béatrice Carsin; Daniel Gedouin; Abderrahmane Hamlat; Isabelle Lecouillard; Guillaume Louvel; Habiba Mesbah; Véronique Quillien; Laurent Riffaud; Thierry Lesimple
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
Marine Gross-Goupil; Thierry Lesimple; Yohann Loriot; Christophe Massard; Marie C Mathieu; Yacine Merrouche; Emmanule Blot; Karim Fizazi
Identifying the primary site using gene expression profiling in patients with carcinoma of an unknown primary (CUP): a feasibility study from the GEFCAPI.

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2012: Véronique Quillien; Stephan Saikali; Marc Sanson; Michel Wager; Frédéric Fina; Jérome Honnorat; L Karayan-Tapon; Marianne Labussière; Audrey Lavenu; Thierry Lesimple; Catherine Carpentier; Olivier Chinot; Dominique Figarella-Branger
Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of 100 glioblastoma patients.
Cancer 2012;118(17):4201-11.
2012: Elodie Vauleon; Odile Audrain; Béatrice Carsin; Daniel Gedouin; Abderrahmane Hamlat; Isabelle Lecouillard; Guillaume Louvel; Habiba Mesbah; Véronique Quillien; Laurent Riffaud; Thierry Lesimple
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
Bulletin du cancer 2012;99(2):121-6.
2012: Marine Gross-Goupil; Thierry Lesimple; Yohann Loriot; Christophe Massard; Marie C Mathieu; Yacine Merrouche; Emmanule Blot; Karim Fizazi
Identifying the primary site using gene expression profiling in patients with carcinoma of an unknown primary (CUP): a feasibility study from the GEFCAPI.
Onkologie 2012;35(1-2):54-5.
2011: Véronique Quillien; Elodie Vauléon; Stephan Saikali; Thierry Lesimple; Abderrahmane Hamlat; Amandine Etcheverry; Jean Mosser
[MGMT analysis in gliomas].
Bulletin du cancer 2011;98(3):291-303.
2011: Marie de Tayrac; Marc Aubry; Stephan Saïkali; Amandine Etcheverry; Cyrille Surbled; Frédérique Guénot; Marie-Dominique Galibert; Abderrahmane Hamlat; Thierry Lesimple; Véronique Quillien; philippe menei; Jean Mosser
A 4-gene signature associated with clinical outcome in high-grade gliomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(2):317-27.
2010: Aline Primot; Ariane Mogha; Sébastien Corre; Karen Roberts; Julien Debbache; Henri Adamski; Brigitte Dreno; Amir Khammari; Thierry Lesimple; Agnes Mereau; Colin R Goding; Marie-Dominique Galibert
ERK-regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma.
Pigment cell & melanoma research 2010;23(1):93-102.
2008: Véronique Descheemaeker; Etienne Garin; Karine Morcel; Thierry Lesimple; Florence Burtin; Jean Levêque
Radioisotopic location of the sentinel node in vaginal mucous melanoma before laparoscopic sampling.
Surgical laparoscopy, endoscopy & percutaneous techniques 2008;18(2):195-6.
2008: Nadège Bercovici; Nacilla Haicheur; Severine Massicard; Frédérique Vernel-Pauillac; Olivier Adotevi; Didier Landais; Isabelle Gorin; Caroline Robert; H Miles Prince; Jean-Jacques Grob; Marie-Thérèse Leccia; Thierry Lesimple; John Wijdenes; Jacques Bartholeyns; Wolf H Fridman; Margarita Salcedo; Estelle Ferries; Eric Tartour
Analysis and characterization of antitumor T-cell response after administration of dendritic cells loaded with allogeneic tumor lysate to metastatic melanoma patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(1):101-12.
2007: Christophe Massard; Jean-Jacques Voigt; Agnès Laplanche; Stéphane Culine; Alain Lortholary; Roland Bugat; Christine Theodore; Frank Priou; Marie-Christine Kaminsky; Thierry Lesimple; Xavier Pivot; Bruno Coudert; Jean-Yves Douillard; Yacine Merrouche; Karim Fizazi
Carcinoma of an unknown primary: are EGF receptor, Her-2/neu, and c-Kit tyrosine kinases potential targets for therapy?
British journal of cancer 2007;97(7):857-61.
2007: Etienne Garin; Florence Prigent-Lejeune; Thierry Lesimple; Marie-Luce Barge; Caroline Rousseau; Anne Devillers; Catherine Bouriel; Mesbah T Habiba; Anne-Marie Bernard; Boumédienne Bridji; Isabelle Resche
Impact of PET-FDG in the diagnosis and therapeutic care of patients presenting with metastases of unknown primary.
Cancer investigation 2007;25(4):232-9.
2006: Thierry Lesimple; Eve-Marie Neidhard; Virginie Vignard; Claudia Lefeuvre; Henri Adamski; Nathalie Labarrière; André Carsin; Delphine Monnier; Brigitte Collet; Gilles Clapisson; Brigitte Birebent; Irène Philip; Louis Toujas; Mohamed Chokri; Véronique Quillien
Immunologic and clinical effects of injecting mature peptide-loaded dendritic cells by intralymphatic and intranodal routes in metastatic melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7380-8.
2006: Abderrahmane Hamlat; Stephan Saikali; Jacques Chaperon; Beatrice Carsin-Nicol; Michéle Le Calve; Thierry Lesimple; Mohamed Ben Hassel; Yvon Guegan
Proposal of a scoring scale as a survival predictor in intracranial oligodendrogliomas.
Journal of neuro-oncology 2006;79(2):159-68.
2006: Laurent Riffaud; Marc Bernard; Thierry Lesimple; Xavier Morandi
Radiation-induced spinal cord glioma subsequent to treatment of Hodgkin's disease: case report and review.
Journal of neuro-oncology 2006;76(2):207-11.
2005: Véronique Quillien; Annick Moisan; André Carsin; Thierry Lesimple; Claudia Lefeuvre; Henri Adamski; Nicolas Bertho; Anne Devillers; Claudine Leberre; Louis Toujas
Biodistribution of radiolabelled human dendritic cells injected by various routes.
European journal of nuclear medicine and molecular imaging 2005;32(7):731-41.
2005: Alban Gervais; Jean Levêque; Françoise Bouet-Toussaint; Florence Burtin; Thierry Lesimple; Laurent Sulpice; Jean-Jacques Patard; Noëlle Genetet; Véronique Catros-Quemener
Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency.
Breast cancer research : BCR 2005;7(3):R326-35.
2004: Abderrahmane Hamlat; Carlos Casallo-Quilliano; Stephan Saikali; Thierry Lesimple; Gilles Brassier
Epithelioid hemangioendothelioma of the infundibular-hypothalamic region: case report and literature review.
Journal of neuro-oncology 2004;67(3):361-6.
2004: Pierre Fumoleau; Rémy Largillier; C Clippe; V Dièras; Hubert Orfeuvre; Thierry Lesimple; S Culine; Bruno Audhuy; Daniel Serin; Hervé Curé; E Vuillemin; J-F Morère; F Montestruc; Z Mouri; Moïse Namer
Multicentre, phase II study evaluating capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer.
European journal of cancer (Oxford, England : 1990) 2004;40(4):536-42.
2004: Chantal Rodary; V Pezet-Langevin; S Garcia-Acosta; Thierry Lesimple; Alain Lortholary; Marie-Christine Kaminsky; Jaafar Bennouna; Stéphane Culine; Hugues Bourgeois; Karim Fizazi
Patient preference for either the EORTC QLQ-C30 or the FACIT Quality Of Life (QOL) measures: a study performed in patients suffering from carcinoma of an unknown primary site (CUP).
European journal of cancer (Oxford, England : 1990) 2004;40(4):521-8.
2003: Thierry Lesimple; Jean-Jacques Voigt; Anne Bataillard; Jean-Michel Coindre; Stéphane Culine; Alain Lortholary; Yacine Merrouche; Gérard Ganem; Marie-Christine Kaminsky; Sylvie Negrier; Maurice Perol; Pierre Bedossa; Gérard Bertrand; Roland Bugat; Karim Fizazi
[Clinical practice guidelines: Standards, Options and Recommendations for the diagnosis of carcinomas of unknown primary site].
Bulletin du cancer 2003;90(12):1071-96.
2003: Thierry Lesimple; Mohammed B Hassel; Daniel Gédouin; Eric Seigneuret; Béatrice Carsin; Abderrahmane Hamlat; Laurent Riffaud; Hélène Simon; Jean-Pierre Malhaire; Yvon Guégan
Phase I study of topotecan in combination with concurrent radiotherapy in adults with glioblastoma.
Journal of neuro-oncology 2003;65(2):141-8.
2003: Stéphane Culine; Alain Lortholary; Jean-Jacques Voigt; Roland Bugat; Christine Théodore; Frank Priou; Marie-Christine Kaminsky; Thierry Lesimple; Xavier Pivot; Bruno Coudert; Jean-Yves Douillard; Yacine Merrouche; Jelila Allouache; Alain Goupil; Sylvie Négrier; Juliette Viala; Peter Petrow; Jeannine Bouzy; Agnès Laplanche; Karim Fizazi
Cisplatin in combination with either gemcitabine or irinotecan in carcinomas of unknown primary site: results of a randomized phase II study--trial for the French Study Group on Carcinomas of Unknown Primary (GEFCAPI 01).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(18):3479-82.
2003: Véronique Quillien; Thierry Lesimple; Louis Toujas
[Vaccinal cell therapy in melanoma].
Bulletin du cancer 2003;90(8-9):722-33.
2003: Roland Bugat; Anne Bataillard; Thierry Lesimple; Jean-Jacques Voigt; Stéphane Culine; Alain Lortholary; Yacine Merrouche; Gérard Ganem; Marie-Christine Kaminsky; Sylvie Negrier; Maurice Perol; Céline Laforêt; Pierre Bedossa; Gérard Bertrand; Jean-Michel Coindre; Karim Fizazi
Summary of the Standards, Options and Recommendations for the management of patients with carcinoma of unknown primary site (2002).
British journal of cancer 2003;89 Suppl 1():S59-66.
2003: Thierry Lesimple; Annick Moisan; André Carsin; Isabelle Ollivier; Mireille Mousseau; Bernard Meunier; Claudine Leberre; Brigitte Collet; Véronique Quillien; Bernard Drenou; Claudia Lefeuvre-Plesse; Jacqueline Chevrant-Breton; Louis Toujas
Injection by various routes of melanoma antigen-associated macrophages: biodistribution and clinical effects.
Cancer immunology, immunotherapy : CII 2003;52(7):438-44.
2003: F Mornex; L Thomas; P Mohr; A Hauschild; Michèle Delaunay; Thierry Lesimple; W Tilgen; B B Nguyen; B Guillot; J Ulrich; Sylvain Bourdin; Mireille Mousseau; D Cupissol; Jacques Bonneterre; C de Gislain; J R Bensadoun; MD Clavel
[Randomised phase III trial of fotemustine versus fotemustine plus whole brain irradiation in cerebral metastases of melanoma].
Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2003;7(1):1-8.
2003: F Mornex; L Thomas; P Mohr; A Hauschild; Michèle Delaunay; Thierry Lesimple; W Tilgen; B N Bui; B Guillot; J Ulrich; Sylvain Bourdin; Mireille Mousseau; D Cupissol; M E Bonneterre; C De Gislain; René-Jean Bensadoun; MD Clavel
A prospective randomized multicentre phase III trial of fotemustine plus whole brain irradiation versus fotemustine alone in cerebral metastases of malignant melanoma.
Melanoma research 2003;13(1):97-103.
2003: Jaafar Bennouna; Rémi Delva; F Gomez; Thierry Lesimple; Lionel Geoffrois; C Linassier; C Chevreau; Jean-Yves Douillard; Sylvie Négrier
A phase II study with 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX-4 regimen) in patients with metastatic renal cell carcinoma.
Oncology 2003;64(1):25-7.
2002: Stéphane Culine; Andrew Kramar; Mahasti Saghatchian; Roland Bugat; Thierry Lesimple; Alain Lortholary; Yacine Merrouche; Agnès Laplanche; Karim Fizazi
Development and validation of a prognostic model to predict the length of survival in patients with carcinomas of an unknown primary site.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(24):4679-83.
2002: Roland Bugat; Anne Bataillard; Thierry Lesimple; Jean-Jacques Voigt; Stéphane Culine; Alain Lortholary; Yacine Merrouche; Gérard Ganem; Marie-Christine Kaminsky; Sylvie Negrier; Maurice Perol; Céline Laforêt; Pierre Bedossa; Gérard Bertrand; Jean-Michel Coindre; Karim Fizazi
[Standards, Options and Recommendations for the management of patient with carcinoma of unknown primary site].
Bulletin du cancer 2002;89(10):869-75.
2002: Bernard Escudier; Jean Pierre Droz; Frédéric Rolland; M J Terrier-Lacombe; G Gravis; Philippe Beuzeboc; B Chauvet; Christine Chevreau; Jean-Christophe Eymard; Thierry Lesimple; Yacine Merrouche; Stéphane Oudard; Frank Priou; C Guillemare; Sophie Gourgou; Stéphane Culine
Doxorubicin and ifosfamide in patients with metastatic sarcomatoid renal cell carcinoma: a phase II study of the Genitourinary Group of the French Federation of Cancer Centers.
The Journal of urology 2002;168(3):959-61.
2002: Eric Raymond; Mario Campone; Roger Stupp; Johan Menten; Philippe Chollet; Thierry Lesimple; R Fety-Deporte; Denis Lacombe; Xavier Paoletti; Pierre Fumoleau
Multicentre phase II and pharmacokinetic study of RFS2000 (9-nitro-camptothecin) administered orally 5 days a week in patients with glioblastoma multiforme.
European journal of cancer (Oxford, England : 1990) 2002;38(10):1348-50.
2001: Véronique Quillien; Annick Moisan; Thierry Lesimple; Claudine Leberre; Louis Toujas
Biodistribution of 111indium-labeled macrophages infused intravenously in patients with renal carcinoma.
Cancer immunology, immunotherapy : CII 2001;50(9):477-82.
2000: Sylvie Négrier; Armelle Caty; Thierry Lesimple; Jean-Yves Douillard; Bernard Escudier; Jean-François Rossi; Patrice Viens; F Gomez
Treatment of patients with metastatic renal carcinoma with a combination of subcutaneous interleukin-2 and interferon alfa with or without fluorouracil. Groupe Français d'Immunothérapie, Fédération Nationale des Centres de Lutte Contre le Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(24):4009-15.
2000: Thierry Lesimple; Annick Moisan; François Guillé; Claudine Leberre; R Audran; Bernard Drenou; Louis Toujas
Treatment of metastatic renal cell carcinoma with activated autologous macrophages and granulocyte--macrophage colony-stimulating factor.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(6):675-9.
2000: Françoise Bouet-Toussaint; N Genetel; Nathalie Rioux-Leclercq; Jean-Yves Bansard; Jean Levêque; François Guillé; Jean-Jacques Patard; Thierry Lesimple; Véronique Catros-Quemener
Interleukin-2 expanded lymphocytes from lymph node and tumor biopsies of human renal cell carcinoma, breast and ovarian cancer.
European cytokine network 2000;11(2):217-24.
2000: Michel Brouard; Véronique Quillien; Isabelle Ollivier; Thierry Lesimple; Henri Adamski; Jacqueline Chevrant-Breton
[Serum S100B protein and stage of cutaneous melanoma: a prospective study].
Annales de dermatologie et de vénéréologie 2000;127(1):56-9.
1999: Catherine Lhommé; P Vennin; N Callet; Thierry Lesimple; J L Achard; Jean Chauvergne; Elisabeth Luporsi; P Chinet-Charrot; Bruno Coudert; J E Couette; Jean-Paul Guastalla; D Lebrun; S Ispas; Joëlle Blumberg
A multicenter phase II study with triptorelin (sustained-release LHRH agonist) in advanced or recurrent endometrial carcinoma: a French anticancer federation study.
Gynecologic oncology 1999;75(2):187-93.
1999: Alain Ravaud; Christophe Bedane; Lionel Geoffrois; Thierry Lesimple; Michèle Delaunay
Toxicity and feasibility of adjuvant high-dose interferon alpha-2b in patients with melanoma in clinical oncologic practice.
British journal of cancer 1999;80(11):1767-9.
1998: Thierry Lesimple; Annick Moisan; Louis Toujas
Autologous human macrophages and anti-tumour cell therapy.
Research in immunology 1998;149(7-8):663-71.
1998: Alain Ravaud; Bruno Audhuy; F Gomez; Bernard Escudier; Thierry Lesimple; Christine Chevreau; Jean-Yves Douillard; Armelle Caty; Lionel Geoffrois; J M Ferrero; C Linassier; M Drevon; Sylvie Négrier
Subcutaneous interleukin-2, interferon alfa-2a, and continuous infusion of fluorouracil in metastatic renal cell carcinoma: a multicenter phase II trial. Groupe Français d'Immunothérapie.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(8):2728-32.
1998: Jean Levêque; Eric Watier; Thierry Lesimple; F Goyat; Jean-Yves Grall
[Intracystic breast carcinoma. A case report].
Journal de gynécologie, obstétrique et biologie de la reproduction 1998;27(3):329-32.