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Kimberly Leslie

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Kimberly K Leslie; Andre T Baron; Kathleen M Darcy; Edgar Fischer; Andrew K Godwin; Parviz Hanjani; Robert S Mannel; Russell J Schilder; Michael W Sill; Meenakshi Singh; Krishnansu S Tewari; Jason A Wilken; Nita J Maihle
A phase II evaluation of gefitinib in the treatment of persistent or recurrent endometrial cancer: A Gynecologic Oncology Group study.
Xiangbing Meng; Xiaofang Wang; Xinjun Wang; Zhi Xiong; Shujie Yang; Yuping Zhang; Danlin Zhu; Lina Albitar; Pavla Brachova; Donghai Dai; Fiorenza Ianzini; Elizabeth A Kosmacek; Laura L Laidler; Dawei Liu; Michael A Mackey; Kimberly K Leslie
Induction of mitotic cell death by overriding G2/M checkpoint in endometrial cancer cells with non-functional p53.
Kimberly K Leslie; Ovadia Abulafia; Edgar G Fischer; Andrew K Godwin; Heidi Gray; Parviz Hanjani; Heather A Lankes; Russell J Schilder; Michael W Sill; Krishnansu Tewari; Joan L Walker; Peter G Rose
Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer.

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All Publications

2013: Kimberly K Leslie; Andre T Baron; Kathleen M Darcy; Edgar Fischer; Andrew K Godwin; Parviz Hanjani; Robert S Mannel; Russell J Schilder; Michael W Sill; Meenakshi Singh; Krishnansu S Tewari; Jason A Wilken; Nita J Maihle
A phase II evaluation of gefitinib in the treatment of persistent or recurrent endometrial cancer: A Gynecologic Oncology Group study.
Gynecologic oncology 2013;129(3):486-94.
2013: Xiangbing Meng; Xiaofang Wang; Xinjun Wang; Zhi Xiong; Shujie Yang; Yuping Zhang; Danlin Zhu; Lina Albitar; Pavla Brachova; Donghai Dai; Fiorenza Ianzini; Elizabeth A Kosmacek; Laura L Laidler; Dawei Liu; Michael A Mackey; Kimberly K Leslie
Induction of mitotic cell death by overriding G2/M checkpoint in endometrial cancer cells with non-functional p53.
Gynecologic oncology 2013;128(3):461-9.
2012: Kimberly K Leslie; Ovadia Abulafia; Edgar G Fischer; Andrew K Godwin; Heidi Gray; Parviz Hanjani; Heather A Lankes; Russell J Schilder; Michael W Sill; Krishnansu Tewari; Joan L Walker; Peter G Rose
Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer.
Gynecologic oncology 2012;127(2):345-50.
2012: Matthew J Carlson; Kristina W Thiel; Shujie Yang; Kimberly K Leslie
Catch it before it kills: progesterone, obesity, and the prevention of endometrial cancer.
Discovery medicine 2012;14(76):215-22.
2012: Kimberly K Leslie; Kristina W Thiel; Koen De Geest; Michael J Goodheart; Yichen Jia; Shujie Yang
Endometrial cancer.
Obstetrics and gynecology clinics of North America 2012;39(2):255-68.
2012: Xiangbing Meng; Xinjun Wang; Zhi Xiong; Shujie Yang; Yuping Zhang; Danlin Zhu; Pavla Brachova; Kimberly K Leslie
Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.
The Journal of biological chemistry 2012;287(7):4485-91.
2012: Kimberly K Leslie; Kristina W Thiel; Shujie Yang
Endometrial cancer: potential treatment and prevention with progestin-containing intrauterine devices.
Obstetrics and gynecology 2012;119(2 Pt 2):419-20.
2012: Kara M Gwin; Armida Moreno; Kimberley Peters; Ronald Schrader; Kristina W Thiel; Kimberly K Leslie
An exploratory study of the variables impacting preterm birth rates in New Mexico.
BMC pregnancy and childbirth 2012;12():53.
2011: Eric J Devor; Michael J Goodheart; Adriann M Hovey; Shyam Ramachandran; Kimberly K Leslie
microRNA expression profiling of endometrial endometrioid adenocarcinomas and serous adenocarcinomas reveals profiles containing shared, unique and differentiating groups of microRNAs.
Oncology reports 2011;26(4):995-1002.
2011: Shujie Yang; Kristina W Thiel; Koenraad De Geest; Kimberly K Leslie
Endometrial cancer: reviving progesterone therapy in the molecular age.
Discovery medicine 2011;12(64):205-12.
2011: Suzy Davies; Donghai Dai; Gavin Pickett; Kristina W Thiel; Victoria P Korovkina; Kimberly K Leslie
Effects of bevacizumab in mouse model of endometrial cancer: Defining the molecular basis for resistance.
Oncology reports 2011;25(3):855-62.
2011: Shujie Yang; Xiangbing Meng; Xue Xiao; Kimberly K Leslie
A mechanism for synergy with combined mTOR and PI3 kinase inhibitors.
PloS one 2011;6(10):e26343.
2011: J Bolnick; L L Laidler; R Abdullah; Lina Albitar; Kimberly K Leslie
Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKBα/AKT and Induces Apoptosis.
Obstetrics and gynecology international 2011;2011():896896.
2011: Brandon M Schickling; Douglas R Spitz; Nukhet Aykin-Burns; Kimberly K Leslie; Victoria P Korovkina
An inhibitor of K+ channels modulates human endometrial tumor-initiating cells.
Cancer cell international 2011;11(1):25.
2011: Xiangbing Meng; Kristina W Thiel; Zhi Xiong; Shujie Yang; Yuping Zhang; Pavla Brachova; Kimberly K Leslie
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
PloS one 2011;6(6):e20920.
2010: Wentao Luo; Fan Wu; Ruba Elmaoued; Brandon B Beck; Edgar Fischer; Xiangbing Meng; Kimberly K Leslie; Donghai Dai
Amifostine enhancement of the anti-cancer effects of paclitaxel in endometrial cancer is TP53-dependent.
International journal of oncology 2010;37(5):1187-94.
2010: Lina Albitar; Gavin Pickett; Marilee Morgan; Jason A Wilken; Nita Maihle; Kimberly K Leslie
EGFR isoforms and gene regulation in human endometrial cancer cells.
Molecular cancer 2010;9():166.
2008: Eliza M F Berkley; Kimberly K Leslie; Sanjeev Arora; Clifford Qualls; Jeffrey C Dunkelberg
Chronic hepatitis C in pregnancy.
Obstetrics and gynecology 2008;112(2 Pt 1):304-10.
2007: Kimberly K Leslie; Sarah A Walter; Kathleen Torkko; Janet K Stephens; Chesney Thompson; Meenakshi Singh
Effect of tamoxifen on endometrial histology, hormone receptors, and cervical cytology: a prospective study with follow-up.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2007;15(3):284-93.
2007: Alice A Robinson; William J Watson; Kimberly K Leslie
Targeted treatment using monoclonal antibodies and tyrosine-kinase inhibitors in pregnancy.
The lancet oncology 2007;8(8):738-43.
2007: Meenakshi Singh; Richard J Zaino; Virginia J Filiaci; Kimberly K Leslie
Relationship of estrogen and progesterone receptors to clinical outcome in metastatic endometrial carcinoma: a Gynecologic Oncology Group Study.
Gynecologic oncology 2007;106(2):325-33.
2007: Lina Albitar; Gavin Pickett; Marilee Morgan; Suzy Davies; Kimberly K Leslie
Models representing type I and type II human endometrial cancers: Ishikawa H and Hec50co cells.
Gynecologic oncology 2007;106(1):52-64.
2007: Lina Albitar; Mark B Carter; Suzy Davies; Kimberly K Leslie
Consequences of the loss of p53, RB1, and PTEN: relationship to gefitinib resistance in endometrial cancer.
Gynecologic oncology 2007;106(1):94-104.
2007: Irv Feldman; Gerald M Feldman; Charlotte Mobarak; Jeffrey C Dunkelberg; Kimberly K Leslie
Identification of proteins within the nuclear factor-kappa B transcriptional complex including estrogen receptor-alpha.
American journal of obstetrics and gynecology 2007;196(4):394.e1-11; discussion 394.e11-3.
2007: Harriet O Smith; Kimberly K Leslie; Meenakshi Singh; Clifford R Qualls; Chetana M Revankar; Nancy E Joste; Eric R Prossnitz
GPR30: a novel indicator of poor survival for endometrial carcinoma.
American journal of obstetrics and gynecology 2007;196(4):386.e1-9; discussion 386.e9-11.
2006: Laurence A Cole; Donghai Dai; Stephen Butler; Kimberly K Leslie; Ernest I Kohorn
Gestational trophoblastic diseases: 1. Pathophysiology of hyperglycosylated hCG.
Gynecologic oncology 2006;102(2):145-50.
2006: Suzy Davies; Donghai Dai; Gavin Pickett; Kimberly K Leslie
Gene regulation profiles by progesterone and dexamethasone in human endometrial cancer Ishikawa H cells.
Gynecologic oncology 2006;101(1):62-70.
2005: Lina Albitar; Laura L Laidler; Rony Abdallah; Kimberly K Leslie
Regulation of signaling phosphoproteins by epidermal growth factor and Iressa (ZD1839) in human endometrial cancer cells that model type I and II tumors.
Molecular cancer therapeutics 2005;4(12):1891-9.
2005: Kimberly K Leslie; Christine Koil; William F Rayburn
Chemotherapeutic drugs in pregnancy.
Obstetrics and gynecology clinics of North America 2005;32(4):627-40.
2005: Kimberly K Leslie; Carol A Lange
Breast cancer and pregnancy.
Obstetrics and gynecology clinics of North America 2005;32(4):547-58.
2005: Donghai Dai; Anna M Holmes; Tan Nguyen; Suzy Davies; Daniel Theele; Claire Verschraegen; Kimberly K Leslie
A potential synergistic anticancer effect of paclitaxel and amifostine on endometrial cancer.
Cancer research 2005;65(20):9517-24.
2005: Kimberly K Leslie; Pamela Dipasquale-Lehnerz; Marcia Smith
Obstetric forceps training using visual feedback and the isometric strength testing unit.
Obstetrics and gynecology 2005;105(2):377-82.
2005: Kimberly K Leslie; Eve Espey
Oral contraceptives and skin cancer: is there a link?
American journal of clinical dermatology 2005;6(6):349-55.
2005: Donghai Dai; Lina Albitar; Tan Nguyen; Laura L Laidler; Meenakshi Singh; Kimberly K Leslie
A therapeutic model for advanced endometrial cancer: systemic progestin in combination with local adenoviral-mediated progesterone receptor expression.
Molecular cancer therapeutics 2005;4(1):169-75.
2005: Kimberly K Leslie; Mary-Pat Stein; Nirmala S Kumar; Donghai Dai; Janet Stephens; Angela Wandinger-Ness; Deborah H Glueck
Progesterone receptor isoform identification and subcellular localization in endometrial cancer.
Gynecologic oncology 2005;96(1):32-41.
2004: Suzy Davies; Donghai Dai; Douglas M Wolf; Kimberly K Leslie
Immunomodulatory and transcriptional effects of progesterone through progesterone A and B receptors in Hec50co poorly differentiated endometrial cancer cells.
Journal of the Society for Gynecologic Investigation 2004;11(7):494-9.
2004: Suzy Davies; Donghai Dai; Irv Feldman; Gavin Pickett; Kimberly K Leslie
Identification of a novel mechanism of NF-kappaB inactivation by progesterone through progesterone receptors in Hec50co poorly differentiated endometrial cancer cells: induction of A20 and ABIN-2.
Gynecologic oncology 2004;94(2):463-70.
2003: Donghai Dai; Elizabeth S Litman; Eric Schonteich; Kimberly K Leslie
Progesterone regulation of activating protein-1 transcriptional activity: a possible mechanism of progesterone inhibition of endometrial cancer cell growth.
The Journal of steroid biochemistry and molecular biology 2003;87(2-3):123-31.
2002: Kimberly K Leslie
Chemotherapy and pregnancy.
Clinical obstetrics and gynecology 2002;45(1):153-64.
2002: Ronald S Gibbs; Jill K Davies; Robert S McDuffie; Kimberly K Leslie; Michael P Sherman; Charles A Centretto; Douglas M Wolf
Chronic intrauterine infection and inflammation in the preterm rabbit, despite antibiotic therapy.
American journal of obstetrics and gynecology 2002;186(2):234-9.
2002: Donghai Dai; Douglas M Wolf; Elizabeth S Litman; Michael J White; Kimberly K Leslie
Progesterone inhibits human endometrial cancer cell growth and invasiveness: down-regulation of cellular adhesion molecules through progesterone B receptors.
Cancer research 2002;62(3):881-6.
2001: Donghai Dai; NS Kumar; Douglas M Wolf; Kimberly K Leslie
Molecular tools to reestablish progestin control of endometrial cancer cell proliferation.
American journal of obstetrics and gynecology 2001;184(5):790-7.
2001: Robert S McDuffie; Jill K Davies; Kimberly K Leslie; S Lee; Michael P Sherman; Ronald S Gibbs
A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy.
Infectious diseases in obstetrics and gynecology 2001;9(4):233-7.
2000: Jill K Davies; Robert Shikes; Chun-I Sze; Kimberly K Leslie; Robert S McDuffie; Roberto Romero; Ronald S Gibbs
Histologic inflammation in the maternal and fetal compartments in a rabbit model of acute intra-amniotic infection.
American journal of obstetrics and gynecology 2000;183(5):1088-93.
2000: Kimberly K Leslie; S L Lee; S M Woodcock; Jill K Davies; Robert S McDuffie; E Hirsch; Michael P Sherman; JL Eskens; Ronald S Gibbs
Acute intrauterine infection results in an imbalance between pro- and anti-inflammatory cytokines in the pregnant rabbit.
American journal of reproductive immunology (New York, N.Y. : 1989) 2000;43(5):305-11.
2000: Kimberly K Leslie; Leonid L Reznikov; F R Simon; Paul V Fennessey; H Reyes; J Ribalta
Estrogens in intrahepatic cholestasis of pregnancy.
Obstetrics and gynecology 2000;95(3):372-6.
1999: Kimberly K Leslie; NS Kumar
Endocrine cancer risks for women during the perimenopause and beyond.
Seminars in reproductive endocrinology 1999;17(4):359-70.
1998: NS Kumar; Jennifer K Richer; Gareth Owen; Elizabeth S Litman; Kathryn B Horwitz; Kimberly K Leslie
Selective down-regulation of progesterone receptor isoform B in poorly differentiated human endometrial cancer cells: implications for unopposed estrogen action.
Cancer research 1998;58(9):1860-5.
1997: Kimberly K Leslie; NS Kumar; Jennifer K Richer; Gareth Owen; Glenn S Takimoto; Kathryn B Horwitz; Carol A Lange
Differential expression of the A and B isoforms of progesterone receptor in human endometrial cancer cells. Only progesterone receptor B is induced by estrogen and associated with strong transcriptional activation.
Annals of the New York Academy of Sciences 1997;828():17-26.
1997: Bradley S Hurst; Kimberly K Leslie
The role of oestrogen in follicular development.
Molecular human reproduction 1997;3(8):643-5.
1995: Bradley S Hurst; M Zilberstein; J Y Chou; B Litman; J Stephens; Kimberly K Leslie
Estrogen receptors are present in human granulosa cells.
The Journal of clinical endocrinology and metabolism 1995;80(1):229-32.
1994: Kimberly K Leslie; D Keefe; S Powell; Frederick Naftolin
Estrogen receptors are identified in the glioblastoma cell line U138MG.
Journal of the Society for Gynecologic Investigation 1994;1(3):238-44.
1994: Stacy Zamudio; Kimberly K Leslie; M White; D D Hagerman; Lorna G Moore
Low serum estradiol and high serum progesterone concentrations characterize hypertensive pregnancies at high altitude.
Journal of the Society for Gynecologic Investigation 1994;1(3):197-205.
1994: Kimberly K Leslie; D J Zuckerman; J Schruefer; M Burchell; J Smith; B D Albertson
Oestrogen modulation with parturition in the human placenta.
Placenta 1994;15(1):79-88.
1993: Robert M Silver; K D Heyborne; Kimberly K Leslie
Pregnancy specific beta 1 glycoprotein (SP-1) in maternal serum and amniotic fluid; pre-eclampsia, small for gestational age fetus and fetal distress.
Placenta 1993;14(5):583-9.
1992: Kimberly K Leslie; D M Tasset; Kathryn B Horwitz
Functional analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells.
American journal of obstetrics and gynecology 1992;166(4):1053-61.
1990: Mark Graham II; N L Krett; L A Miller; Kimberly K Leslie; David F Gordon; William M Wood; LL Wei; Kathryn B Horwitz
T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.
Cancer research 1990;50(19):6208-17.