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John Letterio

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Tonibelle N Gatbonton-Schwager; John J Letterio; Gregory P Tochtrop
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
Seunghwan Lim; Seok Hee Park; Chohee Yun; Eunjin Bae; Kyunghee Byun; Suntaek Hong; Jong Pil Im; Byungchul Kim; Hae-Suk Kim; Tae-Aug Kim; Bona Lee; Bonghee Lee; John J Letterio; Seong-Jin Kim
TRAF6 mediates IL-1β/LPS-induced suppression of TGF-β signaling through its interaction with the type III TGF-β receptor.
Tej K Pareek; Michael B Sporn; Anita Zaremba; Lianhua Bai; Abdelmadjid Belkadi; Mark L Cohen; Sashi Kesavapany; Karen T Liby; Sook L Loh; Colin Meyer; Robert H Miller; John J Letterio
Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis.

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2012: Tonibelle N Gatbonton-Schwager; John J Letterio; Gregory P Tochtrop
Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.
Journal of natural products 2012;75(4):591-8.
2012: Seunghwan Lim; Seok Hee Park; Chohee Yun; Eunjin Bae; Kyunghee Byun; Suntaek Hong; Jong Pil Im; Byungchul Kim; Hae-Suk Kim; Tae-Aug Kim; Bona Lee; Bonghee Lee; John J Letterio; Seong-Jin Kim
TRAF6 mediates IL-1β/LPS-induced suppression of TGF-β signaling through its interaction with the type III TGF-β receptor.
PloS one 2012;7(3):e32705.
2011: Tej K Pareek; Michael B Sporn; Anita Zaremba; Lianhua Bai; Abdelmadjid Belkadi; Mark L Cohen; Sashi Kesavapany; Karen T Liby; Sook L Loh; Colin Meyer; Robert H Miller; John J Letterio
Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis.
Scientific reports 2011;1():201.
2010: Tej K Pareek; Eric Lam; Xiaojing Zheng; David Askew; Ashok B Kulkarni; Mark R Chance; Alex Yee-Chen Huang; Kenneth R Cooke; John J Letterio
Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 2010;207(11):2507-19.
2010: Jeffery J Auletta; Jennifer L Alabran; Byung-Gyu Kim; Colin J Meyer; John J Letterio
The synthetic triterpenoid, CDDO-Me, modulates the proinflammatory response to in vivo lipopolysaccharide challenge.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2010;30(7):497-508.
2010: In Kap Ko; Byung-Gyu Kim; Amad Awadallah; Jenifer Mikulan; Paul Lin; John J Letterio; James E Dennis
Targeting improves MSC treatment of inflammatory bowel disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(7):1365-72.
2010: Emily C Barker; Tonibelle N Gatbonton-Schwager; Yong Han; Jennifer E Clay; John J Letterio; Gregory P Tochtrop
Bryonolic acid: a large-scale isolation and evaluation of heme oxygenase 1 expression in activated macrophages.
Journal of natural products 2010;73(6):1064-8.
2010: Jeong-su Do; Pamela J Fink; Lily Li; Rosanne Spolski; Janet Robinson; Warren J Leonard; John J Letterio; Booki Min
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1675-9.
2009: Jens Nolting; Carolin Daniel; Sabine Reuter; Christina Stuelten; Peng Li; Henry Sucov; Byung-Gyu Kim; John J Letterio; Karsten Kretschmer; Hye-Jung Kim; Harald von Boehmer
Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.
The Journal of experimental medicine 2009;206(10):2131-9.
2008: Sneha Ramesh; Xiao-Jun Qi; Gary M Wildey; Janet Robinson; Jeffery Molkentin; John J Letterio; Philip H Howe
TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2.
EMBO reports 2008;9(10):990-7.
2008: Jennifer L Alabran; Adam Cheuk; Karen Liby; Michael B. Sporn; Javed Khan; John J Letterio; Konstantin S Leskov
Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO.
Cancer biology & therapy 2008;7(5):709-17.
2007: Il-Kyoo Park; John J Letterio; James D Gorham
TGF-beta 1 inhibition of IFN-gamma-induced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent.
Molecular immunology 2007;44(13):3283-90.
2006: John J Letterio; Eva Rudikoff; Nga Voong; Steven R Bauer
Transforming growth factor-beta1 sensitivity is altered in Abl-Myc- and Raf-Myc-induced mouse pre-B-cell tumors.
Stem cells (Dayton, Ohio) 2006;24(12):2611-7.
2006: Karen T Liby; Nga Voong; Charlotte R Williams; Renee Risingsong; Darlene B Royce; Tadashi Honda; Gordon W Gribble; Michael B. Sporn; John J Letterio
The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 1):4288-93.
2006: Byung-Gyu Kim; Cuiling Li; Wenhui Qiao; Mizuko Mamura; Barbara Kasprzak; Barbara Kasperczak; Miriam R Anver; Lawrence A Wolfraim; Suntaek Hong; Elizabeth Mushinski; Michael Potter; Seong-Jin Kim; Xin-Yuan Fu; Chuxia Deng; John J Letterio
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer.
Nature 2006;441(7096):1015-9.
2006: Stephanie Dillon; Sudhanshu Agrawal; Kaustuv Banerjee; John J Letterio; Timothy L Denning; Kyra Oswald-Richter; Deborah J Kasprowicz; Kathryn Kellar; Jeff Pare; Thomas Van Dyke; Steven Ziegler; Derya Unutmaz; Bali Pulendran
Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.
The Journal of clinical investigation 2006;116(4):916-28.
2006: Ying-Wei Lin; Rebecca A Nichols; John J Letterio; Peter D Aplan
Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma.
Blood 2006;107(6):2540-3.
2005: Il-Kyoo Park; Leonard D Shultz; John J Letterio; James D Gorham
TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5666-74.
2005: Hyoung-Pyo Kim; Byung-Gyu Kim; John J Letterio; Warren J Leonard
Smad-dependent cooperative regulation of interleukin 2 receptor alpha chain gene expression by T cell receptor and transforming growth factor-beta.
The Journal of biological chemistry 2005;280(40):34042-7.
2005: Marika C Kullberg; Valerie Hay; Allen W Cheever; Mizuko Mamura; Alan Sher; John J Letterio; Ethan M Shevach; Ciriaco Piccirillo
TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.
European journal of immunology 2005;35(10):2886-95.
2005: John J Letterio
TGF-beta signaling in T cells: roles in lymphoid and epithelial neoplasia.
Oncogene 2005;24(37):5701-12.
2005: John J Letterio
Disruption of the TGF-beta pathway and modeling human cancer in mice.
Mutation research 2005;576(1-2):120-31.
2005: Julien C Marie; John J Letterio; Marc A Gavin; Alexander Y Rudensky
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells.
The Journal of experimental medicine 2005;201(7):1061-7.
2005: Lawrence A Wolfraim; John J Letterio
Cutting edge: p27Kip1 deficiency reduces the requirement for CD28-mediated costimulation in naive CD8+ but not CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2481-4.
2004: Mallika Kaviratne; Matthias Hesse; Mary Leusink; Allen W Cheever; Stephen J Davies; James H McKerrow; Lalage M Wakefield; John J Letterio; Thomas A Wynn
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4020-9.
2004: Lawrence A Wolfraim; Thomas M Walz; Zakiya James; Tania Fernandez; John J Letterio
p21Cip1 and p27Kip1 act in synergy to alter the sensitivity of naive T cells to TGF-beta-mediated G1 arrest through modulation of IL-2 responsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3093-102.
2004: Lawrence A Wolfraim; Tania Fernandez; Mizuko Mamura; Walter L Fuller; Rajesh Kumar; Diane E Cole; Stacey DaCosta Byfield; Angelina Felici; Kathleen C Flanders; Thomas M Walz; Anita B Roberts; Peter D Aplan; FRANK BALIS; John J Letterio
Loss of Smad3 in acute T-cell lymphoblastic leukemia.
The New England journal of medicine 2004;351(6):552-9.
2004: Mizuko Mamura; WoonKyu Lee; Timothy J Sullivan; Angelina Felici; Anastasia L Sowers; James P Allison; John J Letterio
CD28 disruption exacerbates inflammation in Tgf-beta1-/- mice: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-beta1.
Blood 2004;103(12):4594-601.
2004: Elena Bodegas; Alfredo Martínez; Laurent L Ozbun; Mercedes Garayoa; John J Letterio; Luis M Montuenga; Sonia B Jakowlew
Depressed adrenomedullin in the embryonic transforming growth factor-beta1 null mouse becomes elevated postnatally.
The International journal of developmental biology 2004;48(1):67-70.
2004: Gabriel Sosne; Lihua Xu; Lisa Prach; Linda K Mrock; Hynda K Kleinman; John J Letterio; Linda D Hazlett; Michelle Kurpakus-Wheater
Thymosin beta 4 stimulates laminin-5 production independent of TGF-beta.
Experimental cell research 2004;293(1):175-83.
2003: Masaki Terabe; So Matsui; Jong Myun Park; Mizuko Mamura; Nancy Noben-Trauth; Debra D Donaldson; Wanjun Chen; Sharon M Wahl; Steve Ledbetter; Bruce Pratt; John J Letterio; William Paul; Jay A Berzofsky
Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.
The Journal of experimental medicine 2003;198(11):1741-52.
2003: Susan C McKarns; John J Letterio; Norbert E Kaminski
Concentration-dependent bifunctional effect of TGF-beta 1 on immunoglobulin production: a role for Smad3 in IgA production in vitro.
International immunopharmacology 2003;3(13-14):1761-74.
2003: S-J Kim; John J Letterio
Transforming growth factor-beta signaling in normal and malignant hematopoiesis.
Leukemia 2003;17(9):1731-7.
2003: Zhouhong Cao; Kathleen C Flanders; Daniel C Bertolette; Lyudmila A Lyakh; Jens U Wurthner; W Tony Parks; John J Letterio; Francis W Ruscetti; Anita B Roberts
Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells.
Blood 2003;101(2):498-507.
2002: Marika C Kullberg; Dragana Jankovic; Peter L Gorelick; Patricia Caspar; John J Letterio; Allen W Cheever; Alan Sher
Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis.
The Journal of experimental medicine 2002;196(4):505-15.
2002: Lawrence A Wolfraim; Gonnie M Alkemade; Biju Alex; Shellyann Sharpe; W Tony Parks; John J Letterio
Development and application of fully functional epitope-tagged forms of transforming growth factor-beta.
Journal of immunological methods 2002;266(1-2):7-18.
2002: Ciriaco Piccirillo; John J Letterio; Angela M Thornton; Rebecca S McHugh; Mizuko Mamura; Hidekazu Mizuhara; Ethan M Shevach
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness.
The Journal of experimental medicine 2002;196(2):237-46.
2002: Denise A Kaminski; John J Letterio; Peter D Burrows
Differential regulation of mouse B cell development by transforming growth factor beta1.
Developmental immunology 2002;9(2):85-95.
2002: Yu-An Yang; Oksana Dukhanina; Binwu Tang; Mizuko Mamura; John J Letterio; Jennifer MacGregor; Sejal C Patel; Shahram Khozin; Zi-Yao Liu; Jeffrey E Green; Miriam R Anver; Glenn Merlino; Lalage M Wakefield
Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects.
The Journal of clinical investigation 2002;109(12):1607-15.
2002: Tania Fernandez; Stephanie Amoroso; Shellyann Sharpe; Gary M Jones; Valery Bliskovski; Alexander L Kovalchuk; Lalage M Wakefield; Seong-Jin Kim; Michael Potter; John J Letterio
Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism.
The Journal of experimental medicine 2002;195(10):1247-55.
2002: Ashok Kulkarni; Tamizchelvi Thyagarajan; John J Letterio
Function of cytokines within the TGF-beta superfamily as determined from transgenic and gene knockout studies in mice.
Current molecular medicine 2002;2(3):303-27.
2002: Kazuhiko Takahara; Yoshiki Omatsu; Yusuke Yashima; Yasuhiro Maeda; Shusaku Tanaka; Tomonori Iyoda; Björn E Clausen; Kazumi Matsubara; John J Letterio; Ralph M Steinman; Yoichi Matsuda; Kayo Inaba; Bjöern Clusen
Identification and expression of mouse Langerin (CD207) in dendritic cells.
International immunology 2002;14(5):433-44.
2001: John J Letterio; T Lehrnbecher; G Pollack; THOMAS WALSH; STEPHEN CHANOCK
Invasive candidiasis stimulates hepatocyte and monocyte production of active transforming growth factor beta.
Infection and immunity 2001;69(8):5115-20.
2001: Yuanshu Dong; L Tang; John J Letterio; Etty N Benveniste
The Smad3 protein is involved in TGF-beta inhibition of class II transactivator and class II MHC expression.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):311-9.
2001: H Hemmi; Miya Yoshino; Hidetoshi Yamazaki; M Naito; Tomonori Iyoda; Yoshiki Omatsu; S Shimoyama; John J Letterio; T Nakabayashi; H Tagaya; Toshiyuki Yamane; M Ogawa; Shin-Ichi Nishikawa; Kazuo Ryoke; Kayo Inaba; Shin-Ichi Hayashi; Takahiro Kunisada
Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta1-dependent cells.
International immunology 2001;13(5):695-704.
2001: T Nakabayashi; KM Sakata; A Sakata; L Kong; C Allen Lau; John J Letterio; Norma Vela-Roch; Norman Talal; Howard Dang
TGF-beta1 null mutation leads to CD154 upregulated expression in affected tissues.
Inflammation 2001;25(2):69-73.
2001: Timothy J Sullivan; John J Letterio; A van Elsas; Mizuko Mamura; J van Amelsfort; S Sharpe; B Metzler; Cynthia A Chambers; James P Allison
Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2587-92.
2000: R M Koch; N S Roche; W Tony Parks; Gillian S Ashcroft; John J Letterio; Anita B Roberts
Incisional wound healing in transforming growth factor-beta1 null mice.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2000;8(3):179-91.
2000: John J Letterio
Murine models define the role of TGF-beta as a master regulator of immune cell function.
Cytokine & growth factor reviews 2000;11(1-2):81-7.
2000: Fariba Navid; John J Letterio; C L Yeung; M Pegtel; Lee Helman
Autocrine Transforming Growth Factor-beta Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein.
Sarcoma 2000;4(3):93-102.
1999: S Kobayashi; K Yoshida; J M Ward; John J Letterio; Glenn Longenecker; L Yaswen; B Mittleman; E Mozes; A B Roberts; Stefan Karlsson; Ashok Kulkarni
Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouse.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):4013-9.
1999: Xiao Yang; John J Letterio; Robert J Lechleider; Lin Chen; R Hayman; H Gu; Anita B Roberts; Chuxia Deng
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta.
The EMBO journal 1999;18(5):1280-91.
1999: Nanjoo Suh; Y Wang; Tadashi Honda; Gordon W Gribble; Ethan Dmitrovsky; W F Hickey; Robert A Maue; Andrew E Place; Donna M Porter; Michael J Spinella; Charlotte R Williams; G Wu; A J Dannenberg; Kathleen C Flanders; John J Letterio; D J Mangelsdorf; C F Nathan; L Nguyen; W W Porter; RF Ren; A B Roberts; N S Roche; K Subbaramaiah; Michael B. Sporn
A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.
Cancer research 1999;59(2):336-41.
1998: H Zaher; Pedro Fernandez-Salguero; John J Letterio; M S Sheikh; Albert J Fornace; Anita B Roberts; Frank J Gonzalez
The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-beta and apoptosis.
Molecular pharmacology 1998;54(2):313-21.
1998: B Tang; Erwin P Böttinger; Sonia B Jakowlew; KM Bagnall; Jennifer Mariano; Miriam R Anver; John J Letterio; Lalage M Wakefield
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.
Nature medicine 1998;4(7):802-7.
1998: Robert A Seder; Thomas Marth; M C Sieve; W Strober; John J Letterio; A B Roberts; Brian L Kelsall
Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):5719-28.
1998: S R Amoroso; N Huang; Anita B Roberts; Michael Potter; John J Letterio
Consistent loss of functional transforming growth factor beta receptor expression in murine plasmacytomas.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):189-94.
1998: Norman Talal; T Nakabayashi; John J Letterio; L Kong; A G Geiser; Howard Dang
Cytokines may prove useful in the treatment of Sjögrens syndrome (SS) dry eye.
Advances in experimental medicine and biology 1998;438():953-8.
1998: John J Letterio; A B Roberts
Regulation of immune responses by TGF-beta.
Annual review of immunology 1998;16():137-61.
1998: Rena N D'Souza; Adriana Cavender; Douglas P Dickinson; A Roberts; John J Letterio
TGF-beta1 is essential for the homeostasis of the dentin-pulp complex.
European journal of oral sciences 1998;106 Suppl 1():185-91.
1998: John J Letterio; Erwin P Böttinger
TGF-beta knockout and dominant-negative receptor transgenic mice.
Mineral and electrolyte metabolism 1998;24(2-3):161-7.
1998: Y Vodovotz; Jeffrey B Kopp; H Takeguchi; Shashi Shrivastav; Deborah Coffin; M S Lucia; James B Mitchell; R Webber; John J Letterio; David A Wink; A B Roberts
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice.
Journal of leukocyte biology 1998;63(1):31-9.
1997: John J Letterio; A B Roberts
TGF-beta: a critical modulator of immune cell function.
Clinical immunology and immunopathology 1997;84(3):244-50.
1997: T A Borkowski; John J Letterio; CRYSTAL MACKALL; A Saitoh; Xiao-Jing Wang; D R Roop; Ronald E Gress; Mark C Udey
A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice.
The Journal of clinical investigation 1997;100(3):575-81.
1997: T Nakabayashi; John J Letterio; A G Geiser; L Kong; N Ogawa; W Zhao; T Koike; Gabriel Fernandes; Howard Dang; Norman Talal
Up-regulation of cytokine mRNA, adhesion molecule proteins, and MHC class II proteins in salivary glands of TGF-beta1 knockout mice: MHC class II is a factor in the pathogenesis of TGF-beta1 knockout mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5527-35.
1997: Erwin P Böttinger; John J Letterio; Anita B Roberts
Biology of TGF-beta in knockout and transgenic mouse models.
Kidney international 1997;51(5):1355-60.
1997: T A Borkowski; John J Letterio; CRYSTAL MACKALL; A Saitoh; A G Farr; Xiao-Jing Wang; D R Roop; Ronald E Gress; Mark C Udey
Langerhans cells in the TGF beta 1 null mouse.
Advances in experimental medicine and biology 1997;417():307-10.
1996: T A Borkowski; John J Letterio; Andrew G Farr; Mark C Udey
A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells.
The Journal of experimental medicine 1996;184(6):2417-22.
1996: John J Letterio; A G Geiser; Ashok Kulkarni; Howard Dang; L Kong; T Nakabayashi; CRYSTAL MACKALL; Ronald E Gress; Anita B Roberts
Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression.
The Journal of clinical investigation 1996;98(9):2109-19.
1996: A O Williams; A D Knapton; A Geiser; John J Letterio; A B Roberts
The liver in transforming growth factor-Beta-1 (TGF-beta 1) null mutant mice.
Ultrastructural pathology 1996;20(5):477-90.
1996: Matthew P Hoffman; M C Kibbey; John J Letterio; Hynda K Kleinman
Role of laminin-1 and TGF-beta 3 in acinar differentiation of a human submandibular gland cell line (HSG).
Journal of cell science 1996;109 ( Pt 8)():2013-21.
1996: Y Vodovotz; John J Letterio; A G Geiser; L Chesler; Anita B Roberts; J Sparrow
Control of nitric oxide production by endogenous TGF-beta1 and systemic nitric oxide in retinal pigment epithelial cells and peritoneal macrophages.
Journal of leukocyte biology 1996;60(2):261-70.
1996: John J Letterio; Anita B Roberts
Transforming growth factor-beta1-deficient mice: identification of isoform-specific activities in vivo.
Journal of leukocyte biology 1996;59(6):769-74.
1996: Y Vodovotz; A G Geiser; L Chesler; John J Letterio; Andrew D Campbell; M S Lucia; Michael B. Sporn; Anita B Roberts
Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.
The Journal of experimental medicine 1996;183(5):2337-42.
1996: M C Velez-Yanguas; Thea Kalebic; M Maggi; C C Kappel; John J Letterio; M Uskokovic; Lee Helman
1 alpha, 25-dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531) modulation of insulin-like growth factor-binding protein-3 and induction of differentiation and growth arrest in a human osteosarcoma cell line.
The Journal of clinical endocrinology and metabolism 1996;81(1):93-9.
1995: Howard Dang; A G Geiser; John J Letterio; T Nakabayashi; L Kong; Gabriel Fernandes; Norman Talal
SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-beta knockout mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):3205-12.
1995: P S Cohen; John J Letterio; C Gaetano; J Chan; K Matsumoto; Michael B. Sporn; Carol Jeanne Thiele
Induction of transforming growth factor beta 1 and its receptors during all-trans-retinoic acid (RA) treatment of RA-responsive human neuroblastoma cell lines.
Cancer research 1995;55(11):2380-6.
1995: Lalage M Wakefield; John J Letterio; T Chen; David Danielpour; R S Allison; L H Pai; A M Denicoff; MH Noone; Kenneth H Cowan; Joyce A O'Shaughnessy
Transforming growth factor-beta1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(1):129-36.
1995: Lalage M Wakefield; John J Letterio; A G Geiser; Kathleen C Flanders; Joyce A O'Shaughnessy; A B Roberts; Michael B. Sporn
Transforming growth factor-beta s in mammary tumorigenesis: promoters or antipromoters?
Progress in clinical and biological research 1995;391():133-48.
1994: John J Letterio; A G Geiser; Ashok Kulkarni; N S Roche; Michael B. Sporn; Anita B Roberts
Maternal rescue of transforming growth factor-beta 1 null mice.
Science (New York, N.Y.) 1994;264(5167):1936-8.
1994: Y Takahama; John J Letterio; H Suzuki; Andrew G Farr; Alfred Singer
Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta.
The Journal of experimental medicine 1994;179(5):1495-506.
1994: M A Anzano; J M Smith; M R Uskoković; C W Peer; L T Mullen; John J Letterio; M C Welsh; M W Shrader; Daniel Logsdon; C L Driver
1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531), a new deltanoid (vitamin D analogue) for prevention of breast cancer in the rat.
Cancer research 1994;54(7):1653-6.
1993: A G Geiser; John J Letterio; Ashok Kulkarni; S Karlsson; Anita B Roberts; Michael B. Sporn
Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):9944-8.
1992: Carolyn A Felix; Marion M Nau; T Takahashi; T Mitsudomi; I Chiba; David G Poplack; G H Reaman; D E Cole; John J Letterio; J Whang-Peng
Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.
The Journal of clinical investigation 1992;89(2):640-7.
1991: Emmanuel Roilides; BU Mueller; John J Letterio; K Butler; PA Pizzo
Agrobacterium radiobacter bacteremia in a child with human immunodeficiency virus infection.
The Pediatric infectious disease journal 1991;10(4):337-8.
1987: T M Bashore; D J Magorien; John J Letterio; P Shaffer; D V Unverferth
Histologic and biochemical correlates of left ventricular chamber dynamics in man.
Journal of the American College of Cardiology 1987;9(4):734-42.