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Christian Leumann

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Occupations

Thermodynamics

Phenomena

Genes & Molecular Sequences

Molecular Structure

Procedures

Ultraviolet Spectrophotometry

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Co-Publications
Name
5
Brotschi, Christine
5
Häberli, Adrian
5
Ittig, Damian
5
Küpfer, Pascal
5
Renneberg, Dorte
4
Ahn, Dae-Ro
3
Buchini, Sabrina
3
Bernal-Méndez, Eloy
3
Mayer, Alain
3
Hollenstein, Marcel
3
Schümperli, Daniel
3
Mosimann, Markus
3
Parel, SP
3
Zahn, Alain
2
Reigadas, Sandrine

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Publications

TOP 3
Kaufmann Marco; Gisler Michael; Leumann Christian J
Stable cyclohexyl-phenyl recognition in the center of a DNA duplex.
Grigorenko Nikolay A; Leumann Christian J
2-Phenanthrenyl-DNA: synthesis, pairing, and fluorescence properties.
Grigorenko Nikolay A; Leumann Christian J
Electron transfer through a stable phenanthrenyl pair in DNA.

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All Publications

2009: Kaufmann Marco; Gisler Michael; Leumann Christian J
Stable cyclohexyl-phenyl recognition in the center of a DNA duplex.
Angewandte Chemie (International ed. in English) 2009;48(21):3810-3.
2009: Grigorenko Nikolay A; Leumann Christian J
2-Phenanthrenyl-DNA: synthesis, pairing, and fluorescence properties.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(3):639-45.
2008: Grigorenko Nikolay A; Leumann Christian J
Electron transfer through a stable phenanthrenyl pair in DNA.
Chemical communications (Cambridge, England) 2008;(42):5417-9.
2008: Luisier Samuel; Leumann Christian J
Screening the structural and functional properties of bicyclo-DNA: bc(ox)-DNA.
Chembiochem : a European journal of chemical biology 2008;9(14):2244-53.
2008: Pallan Pradeep S; Ittig Damian; Héroux Annie; Wawrzak Zdzislaw; Leumann Christian J; Egli Martin
Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
Chemical communications (Cambridge, England) 2008;(7):883-5.
2008: Luisier Samuel; Silhar Peter; Leumann Christian J
Highly beta-selective, N-iodosuccinimide-mediated nucleosidation to bicyclo- and tricyclo-nucleosides.
Nucleic acids symposium series (2004) 2008;(52):581-2.
2008: Ittig Damian; Schümperli Daniel; Leumann Christian J
Tc-DNA modified siRNA.
Nucleic acids symposium series (2004) 2008;(52):501-2.
2008: Stauffiger Andrea; Leumann Christian J
Synthesis and structural analysis of [4.3.0]-bicyclothymidine.
Nucleic acids symposium series (2004) 2008;(52):267-8.
2008: Scheidegger Simon P; Leumann Christian J
Strand invasion properties and serum stability of alpha-tricyclo-DNA.
Nucleic acids symposium series (2004) 2008;(52):139-40.
2008: Zahn Alain; Leumann Christian J
Recognition properties of donor- and acceptor-modified biphenyl-DNA.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(4):1087-94.
2008: Johar Zeena; Zahn Alain; Leumann Christian J; Jaun Bernhard
Solution structure of a DNA duplex containing a biphenyl pair.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(4):1080-6.
2007: Ivanova Gabriela; Arzumanov Andrey; Gait Michael J; Reigadas Sandrine; Toulmé Jean-Jacques; Andreola Marie-Line; Ittig Damian; Leumann Christian
Comparative studies of tricyclo-DNA- and LNA-containing oligonucleotides as inhibitors of HIV-1 gene expression.
Nucleosides, nucleotides & nucleic acids 2007;26(6-7):747-50.
2007: Stauffiger Andrea; Leumann Christian J
Synthesis of the bicyclo-[4.3.0]-thymidyl-nucleoside via pd(II)-mediated ring expansion chemistry.
Nucleosides, nucleotides & nucleic acids 2007;26(6-7):615-9.
2007: Küpfer Pascal A; Leumann Christian J
Photochemically induced RNA and DNA abasic sites.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1177-80.
2007: Küpfer Pascal A; Crey-Desbiolles Caroline; Leumann Christian J
Trans-lesion synthesis and RNaseH activity by reverse transcriptases on a true abasic RNA template.
Nucleic acids research 2007;35(20):6846-53.
2007: Ivanova Gabriela; Reigadas Sandrine; Ittig Damian; Arzumanov Andrey; Andreola Marie-Line; Leumann Christian; Toulmé Jean-Jacques; Gait Michael J
Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity.
Oligonucleotides 2007;17(1):54-65.
2007: Küpfer Pascal A; Leumann Christian J
The chemical stability of abasic RNA compared to abasic DNA.
Nucleic acids research 2007;35(1):58-68.
2006: Scheidegger Simon P; Leumann Christian J
Synthesis and pairing properties of alpha-tricyclo-DNA.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(31):8014-23.
2006: Zahn Alain; Leumann Christian J
Synthesis of functionalized biphenyl-C-nucleosides and their incorporation into oligodeoxynucleotides.
Bioorganic & medicinal chemistry 2006;14(18):6174-88.
2006: Egli Martin; Pallan Pradeep S; Pattanayek Rekha; Wilds Christopher J; Lubini Paolo; Minasov George; Dobler Max; Leumann Christian J; Eschenmoser Albert
Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system.
Journal of the American Chemical Society 2006;128(33):10847-56.
2006: Leumann Christian J
Sugar modification as a means to increase the biological performance of oligonucleotides.
Nucleic acids symposium series (2004) 2006;(50):55-6.
2005: Mosimann Markus; Küpfer Pascal A; Leumann Christian J
Synthesis and incorporation into DNA of a chemically stable, functional abasic site analogue.
Organic letters 2005;7(23):5211-4.
2005: Küpfer Pascal A; Leumann Christian J
RNA abasic sites: preparation and trans-lesion synthesis by HIV-1 reverse transcriptase.
Chembiochem : a European journal of chemical biology 2005;6(11):1970-3.
2005: Mayer Alain; Häberli Adrian; Leumann Christian J
Synthesis and triplex forming properties of pyrrolidino pseudoisocytidine containing oligodeoxynucleotides.
Organic & biomolecular chemistry 2005;3(9):1653-8.
2005: Brotschi Christine; Leumann Christian J
RNA duplexes with biphenyl substituents as base replacements are less stable than DNA duplexes.
Chemical communications (Cambridge, England) 2005;(15):2023-5.
2005: Hollenstein Marcel; Leumann Christian J
Fluorinated olefinic peptide nucleic acid: synthesis and pairing properties with complementary DNA.
The Journal of organic chemistry 2005;70(8):3205-17.
2005: Zahn Alain; Brotschi Christine; Leumann Christian J
pentafluorophenyl-phenyl interactions in biphenyl-DNA.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(7):2125-9.
2005: Brotschi Christine; Mathis Gérald; Leumann Christian J
Bipyridyl- and biphenyl-DNA: a recognition motif based on interstrand aromatic stacking.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(6):1911-23.
2005: Crey-Desbiolles Caroline; Ahn Dae-Ro; Leumann Christian J
Molecular beacons with a homo-DNA stem: improving target selectivity.
Nucleic acids research 2005;33(8):e77.
2004: Renneberg Dorte; Leumann Christian J
Exploring Hoogsteen and reversed-Hoogsteen duplex and triplex formation with tricyclo-DNA purine sequences.
Chembiochem : a European journal of chemical biology 2004;5(8):1114-8.
2004: Buchini Sabrina; Leumann Christian J
Stable and selective recognition of three base pairs in the parallel triple-helical DNA binding motif.
Angewandte Chemie (International ed. in English) 2004;43(30):3925-8.
2004: Ittig Damian; Liu Songkai; Renneberg Dorte; Schümperli Daniel; Leumann Christian J
Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: a comparison of tricyclo-DNA with LNA.
Nucleic acids research 2004;32(1):346-53.
2003: Becaud Jessica; Pompizi Isabelle; Leumann Christian J
Propagation of melting cooperativity along the phosphodiester backbone of DNA.
Journal of the American Chemical Society 2003;125(50):15338-42.
2003: Buchini Sabrina; Leumann Christian J
Recent improvements in antigene technology.
Current opinion in chemical biology 2003;7(6):717-26.
2003: Mayer Alain; Leumann Christian J
A short, efficient synthesis of 2'-deoxypseudoisocytidine based on Heck-chemistry.
Nucleosides, nucleotides & nucleic acids 2003;22(10):1919-25.
2003: Ahn Dae-Ro; Mosimann Markus; Leumann Christian J
Synthesis of cyclopentane amide DNA (cpa-DNA) and its pairing properties.
The Journal of organic chemistry 2003;68(20):7693-9.
2003: Gautschi Daniel; Leumann Christian J
Olefinic peptide nucleic acid (OPA).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1211-3.
2003: Ahn Dae-Ro; Mosimann Markus; Leumann Christian J
Synthesis of a cyclopentane amide DNA analogue and its base pairing properties.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1207-10.
2003: Hirtz Caroline; Leumann Christian J
Synthetic studies towards a novel, chemical stable, abasic site analogue of DNA.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1203-6.
2003: Buchini Sabrina; Leumann Christian J
New nucleoside analogues for the recognition of pyrimidine-purine inversion sites.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1199-201.
2003: Brotschi Christine; Leumann Christian J
Transition metal ligands as novel DNA-base substitutes.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1195-7.
2003: Hollenstein Marcel; Gautschi Daniel; Leumann Christian J
Fluorinated peptide nucleic acid.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1191-4.
2003: Häberli Adrian; Mayer Alain; Leumann Christian J
Pyrrolidino-DNA.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1187-9.
2003: Hollenstein Marcel; Leumann Christian J
Synthesis and incorporation into PNA of fluorinated olefinic PNA (F-OPA) monomers.
Organic letters 2003;5(11):1987-90.
2003: Brotschi Christine; Leumann Christian J
DNA with hydrophobic base substitutes: a stable, zipperlike recognition motif based on interstrand-stacking interactions.
Angewandte Chemie (International ed. in English) 2003;42(14):1655-8.
2002: Ahn Dae-Ro; Egger Anita; Lehmann Christian; Pitsch Stefan; Leumann Christian J
Bicyclo[3.2.1]amide-DNA: a chiral, nonchiroselective base-pairing system.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(23):5312-22.
2002: Bernal-Méndez Eloy; Leumann Christian J
Stability and kinetics of nucleic acid triplexes with chimaeric DNA/RNA third strands.
Biochemistry 2002;41(41):12343-9.
2002: Häberli Adrian; Leumann Christian J
DNA binding properties of oligodeoxynucleotides containing pyrrolidino C-nucleosides.
Organic letters 2002;4(19):3275-8.
2002: Schürch Stefan; Bernal-Méndez Eloy; Leumann Christian J
Electrospray tandem mass spectrometry of mixed-sequence RNA/DNA oligonucleotides.
Journal of the American Society for Mass Spectrometry 2002;13(8):936-45.
2002: Renneberg Dorte; Bouliong Emilie; Reber Ulrich; Schümperli Daniel; Leumann Christian J
Antisense properties of tricyclo-DNA.
Nucleic acids research 2002;30(13):2751-7.
2002: Renneberg Dorte; Leumann Christian J
Watson-Crick base-pairing properties of tricyclo-DNA.
Journal of the American Chemical Society 2002;124(21):5993-6002.
2002: Leumann Christian J
DNA analogues: from supramolecular principles to biological properties.
Bioorganic & medicinal chemistry 2002;10(4):841-54.
2001: Bernal-Méndez E; Leumann C J
Conformational diversity versus nucleic acid triplex stability, a combinatorial study.
The Journal of biological chemistry 2001;276(38):35320-7.
2001: Parel S P; Leumann C J
Triple-helix formation in the antiparallel binding motif of oligodeoxynucleotides containing N(9)- and N(7)-2-aminopurine deoxynucleosides.
Nucleic acids research 2001;29(11):2260-7.
2001: Parel S P; Marfurt J; Leumann C J
DNA triple-helix formation at pyrimidine-purine inversion sites.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):411-7.
2001: Häberli A; Leumann C J
Synthesis of pyrrolidine C-nucleosides via Heck reaction.
Organic letters 2001;3(3):489-92.
2000: Renneberg D; Pfander H; Leumann C J
Total synthesis of coraxeniolide-A.
The Journal of organic chemistry 2000;65(26):9069-79.
2000: Pompizi I; Häberli A; Leumann C J
Oligodeoxynucleotides containing conformationally constrained abasic sites: a UV and fluorescence spectroscopic investigation on duplex stability and structure.
Nucleic acids research 2000;28(14):2702-8.
2000: Stulz E; Bürgi H B; Leumann C
ZrIV-tetraphenylporphyrinates as nuclease mimics: structural, kinetic and mechanistic studies on phosphate diester transesterification.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(3):523-36.
1999: Prévot-Halter I; Leumann C J
Selective recognition of a C-G base-pair in the parallel DNA triple-helical binding motif.
Bioorganic & medicinal chemistry letters 1999;9(18):2657-60.
1998: Epple C; Leumann C
Bicyclo[3.2.1]-DNA, a new DNA analog with a rigid backbone and flexibly linked bases: pairing properties with complementary DNA.
Chemistry & biology 1998;5(4):209-16.
1997: Marfurt J; Parel S P; Leumann C J
Strong, specific, monodentate G-C base pair recognition by N7-inosine derivatives in the pyrimidine.purine-pyrimidine triple-helical binding motif.
Nucleic acids research 1997;25(10):1875-82.
1996: Bolli M; Trafelet H U; Leumann C
Watson-Crick base-pairing properties of bicyclo-DNA.
Nucleic acids research 1996;24(23):4660-7.
1996: Bolli M; Litten J C; Schütz R; Leumann C J
Bicyclo-DNA: a Hoogsteen-selective pairing system.
Chemistry & biology 1996;3(3):197-206.

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