Donald Leung

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Staphylococcus aureus

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Byrne Aideen M; Goleva Elena; Leung Donald Y M
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation.
Leung Donald Y M; Szefler Stanley J;
The editors' choice.
Broccardo Carolyn J; Mahaffey Spencer B; Strand Matthew; Reisdorph Nichole A; Leung Donald Y M
Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis.

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All Publications

2009: Byrne Aideen M; Goleva Elena; Leung Donald Y M
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation.
The Journal of investigative dermatology 2009;129(12):2784-94.
2009: Leung Donald Y M; Szefler Stanley J;
The editors' choice.
The Journal of allergy and clinical immunology 2009;124(5):893-4.
2009: Broccardo Carolyn J; Mahaffey Spencer B; Strand Matthew; Reisdorph Nichole A; Leung Donald Y M
Peeling off the layers: skin taping and a novel proteomics approach to study atopic dermatitis.
The Journal of allergy and clinical immunology 2009;124(5):1113-5.e1-11.
2009: Howell Michael D; Streib Joanne E; Kim Byung Eui; Lesley Leighann J; Dunlap Annegret P; Geng Dianliang; Feng Yanshu; Savage Paul B; Leung Donald Y M
Ceragenins: a class of antiviral compounds to treat orthopox infections.
The Journal of investigative dermatology 2009;129(11):2668-75.
2009: Gao Pei-Song; Rafaels Nicholas M; Hand Tracey; Murray Tanda; Boguniewicz Mark; Hata Tissa; Schneider Lynda; Hanifin Jon M; Gallo Richard L; Gao Li; Beaty Terri H; Beck Lisa A; Barnes Kathleen C; Leung Donald Y M
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.
The Journal of allergy and clinical immunology 2009;124(3):507-13, 513.e1-7.
2009: Leung Donald Y M
Our evolving understanding of the functional role of filaggrin in atopic dermatitis.
The Journal of allergy and clinical immunology 2009;124(3):494-5.
2009: Howell Michael D; Kim Byung Eui; Gao Peisong; Grant Audrey V; Boguniewicz Mark; DeBenedetto Anna; Schneider Lynda; Beck Lisa A; Barnes Kathleen C; Leung Donald Y M
Cytokine modulation of atopic dermatitis filaggrin skin expression.
The Journal of allergy and clinical immunology 2009;124(3 Suppl 2):R7-R12.
2009: Leung Donald Y M
Preface: The epidermal skin barrier: aspects of biology and dysfunction.
The Journal of allergy and clinical immunology 2009;124(3 Suppl 2):R1.
2009: Oyoshi Michiko K; Elkhal Abdallah; Kumar Lalit; Scott Jordan E; Koduru Suresh; He Rui; Leung Donald Y M; Howell Michael D; Oettgen Hans C; Murphy George F; Geha Raif S
Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(35):14954-9.
2009: Zhang Yong; Leung Donald Y M; Nordeen Steven K; Goleva Elena
Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated glucocorticoid receptor dephosphorylation.
The Journal of biological chemistry 2009;284(36):24542-52.
2009: Bin Lianghua; Howell Michael D; Kim Byung Eui; Hall Clifton F; Streib Joanne E; Leung Donald Y M
Inhibition of S100A11 gene expression impairs keratinocyte response against vaccinia virus through downregulation of the IL-10 receptor 2 chain.
The Journal of allergy and clinical immunology 2009;124(2):270-7, 277.e1.
2009: Beck Lisa A; Boguniewicz Mark; Hata Tissa; Schneider Lynda C; Hanifin Jon; Gallo Rich; Paller Amy S; Lieff Susi; Reese Jamie; Zaccaro Daniel; Milgrom Henry; Barnes Kathleen C; Leung Donald Y M
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.
The Journal of allergy and clinical immunology 2009;124(2):260-9, 269.e1-7.
2009: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2008.
The Journal of allergy and clinical immunology 2009;123(2):319-27.
2009: Goleva Elena; Li Ling-Bo; Leung Donald Y M
IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance.
American journal of respiratory cell and molecular biology 2009;40(2):223-30.
2008: Leung Donald Y M
Directing the innate immune response to prevent and control allergic diseases.
The Journal of allergy and clinical immunology 2008;122(5):893-4.
2008: Sutherland E Rand; Goleva Elena; Strand Matthew; Beuther David A; Leung Donald Y M
Body mass and glucocorticoid response in asthma.
American journal of respiratory and critical care medicine 2008;178(7):682-7.
2008: Goleva Elena; Hauk Pia J; Hall Clifton F; Liu Andrew H; Riches David W H; Martin Richard J; Leung Donald Y M
Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages.
The Journal of allergy and clinical immunology 2008;122(3):550-9.e3.
2008: Hauk Pia J; Krawiec Marzena; Murphy James; Boguniewicz Juri; Schiltz Allison; Goleva Elena; Liu Andrew H; Leung Donald Y M
Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing.
Pediatric pulmonology 2008;43(9):916-23.
2008: Howell Michael D; Fairchild Heather R; Kim Byung Eui; Bin Lianghua; Boguniewicz Mark; Redzic Jasmina S; Hansen Kirk C; Leung Donald Y M
Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation.
The Journal of investigative dermatology 2008;128(9):2248-58.
2008: Kisich Kevin O; Carspecken Charles W; Fiéve Stephanie; Boguniewicz Mark; Leung Donald Y M
Defective killing of Staphylococcus aureus in atopic dermatitis is associated with reduced mobilization of human beta-defensin-3.
The Journal of allergy and clinical immunology 2008;122(1):62-8.
2008: Boguniewicz Mark; Nicol Noreen; Kelsay Kim; Leung Donald Y M
A multidisciplinary approach to evaluation and treatment of atopic dermatitis.
Seminars in cutaneous medicine and surgery 2008;27(2):115-27.
2008: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2007.
The Journal of allergy and clinical immunology 2008;121(6):1351-8.
2008: Schlievert Patrick M; Case Laura C; Strandberg Kristi L; Abrams Bea B; Leung Donald Y M
Superantigen profile of Staphylococcus aureus isolates from patients with steroid-resistant atopic dermatitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(10):1562-7.
2008: Bender Bruce G; Ballard Robert; Canono Beth; Murphy James R; Leung Donald Y M
Disease severity, scratching, and sleep quality in patients with atopic dermatitis.
Journal of the American Academy of Dermatology 2008;58(3):415-20.
2008: Kim Byung Eui; Leung Donald Y M; Boguniewicz Mark; Howell Michael D
Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6.
Clinical immunology (Orlando, Fla.) 2008;126(3):332-7.
2008: Shearer William T; Leung Donald Y M
Preface to the 2008 mini-primer on allergic and immunologic disease.
The Journal of allergy and clinical immunology 2008;121(2 Suppl):S363.
2008: Man Mao-Qiang; Hatano Yutaka; Lee Seung H; Man Mona; Chang Sandra; Feingold Kenneth R; Leung Donald Y M; Holleran Walter; Uchida Yoshikazu; Elias Peter M
Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges.
The Journal of investigative dermatology 2008;128(1):79-86.
2007: Scott Jordan E; ElKhal Abdallah; Freyschmidt Eva-Jasmin; MacArthur Daniel H; McDonald Douglas; Howell Michael D; Leung Donald Y M; Laouar Amale; Manjunath N; Bianchi Teresa; Boes Marianne; Oettgen Hans C; Geha Raif S
Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation.
The Journal of allergy and clinical immunology 2007;120(6):1382-8.
2007: Goleva Elena; Hauk Pia J; Boguniewicz Juri; Martin Richard J; Leung Donald Y M
Airway remodeling and lack of bronchodilator response in steroid-resistant asthma.
The Journal of allergy and clinical immunology 2007;120(5):1065-72.
2007: Kisich Kevin O; Howell Michael D; Boguniewicz Mark; Heizer Heather R; Watson Nori U; Leung Donald Y M
The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta-defensin 3.
The Journal of investigative dermatology 2007;127(10):2368-80.
2007: Platts-Mills Thomas; Leung Donald Y M; Schatz Michael
The role of allergens in asthma.
American family physician 2007;76(5):675-80.
2007: Li Ling-bo; Leung Donald Y M; Strand Matthew J; Goleva Elena
ATF2 impairs glucocorticoid receptor-mediated transactivation in human CD8+ T cells.
Blood 2007;110(5):1570-7.
2007: Albanesi Cristina; Fairchild Heather R; Madonna Stefania; Scarponi Claudia; De Pità Ornella; Leung Donald Y M; Howell Michael D
IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):984-92.
2007: Simons F Estelle R; Frew Anthony J; Ansotegui Ignacio J; Bochner Bruce S; Golden David B K; Finkelman Fred D; Leung Donald Y M; Lotvall Jan; Marone Gianni; Metcalfe Dean D; Müller Ulrich; Rosenwasser Lanny J; Sampson Hugh A; Schwartz Lawrence B; van Hage Marianne; Walls Andrew F
Risk assessment in anaphylaxis: current and future approaches.
The Journal of allergy and clinical immunology 2007;120(1 Suppl):S2-24.
2007: Howell Michael D; Kim Byung Eui; Gao Peisong; Grant Audrey V; Boguniewicz Mark; Debenedetto Anna; Schneider Lynda; Beck Lisa A; Barnes Kathleen C; Leung Donald Y M
Cytokine modulation of atopic dermatitis filaggrin skin expression.
The Journal of allergy and clinical immunology 2007;120(1):150-5.
2007: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects.
The Journal of allergy and clinical immunology 2007;119(6):1462-9.
2007: Peng Wenming M; Jenneck Claudia; Bussmann Caroline; Bogdanow Manuela; Hart Juana; Leung Donald Y M; Bieber Thomas; Eis-Hübinger Anna-Maria; Novak Natalija
Risk factors of atopic dermatitis patients for eczema herpeticum.
The Journal of investigative dermatology 2007;127(5):1261-3.
2007: Howell Michael D; Streib Joanne E; Leung Donald Y M
Antiviral activity of human beta-defensin 3 against vaccinia virus.
The Journal of allergy and clinical immunology 2007;119(4):1022-5.
2007: Brouillard Jean-Nicholas P; Günther Sebastian; Varma Ashok K; Gryski Irene; Herfst Christine A; Rahman A K M Nur-ur; Leung Donald Y M; Schlievert Patrick M; Madrenas Joaquín; Sundberg Eric J; McCormick John K
Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens.
Journal of molecular biology 2007;367(4):925-34.
2007: Salt Bryn H; Boguniewicz Mark; Leung Donald Y M
Severe refractory atopic dermatitis in adults is highly atopic.
The Journal of allergy and clinical immunology 2007;119(2):508-9.
2007: Kim Byung Eui; Leung Donald Y M; Streib Joanne E; Kisich Kevin; Boguniewicz Mark; Hamid Qutayba A; Howell Michael D
Macrophage inflammatory protein 3alpha deficiency in atopic dermatitis skin and role in innate immune response to vaccinia virus.
The Journal of allergy and clinical immunology 2007;119(2):457-63.
2006: Howell Michael D; Boguniewicz Mark; Pastore Saveria; Novak Natalija; Bieber Thomas; Girolomoni Giampiero; Leung Donald Y M
Mechanism of HBD-3 deficiency in atopic dermatitis.
Clinical immunology (Orlando, Fla.) 2006;121(3):332-8.
2006: Ong Peck Y; Leung Donald Y M
Immune dysregulation in atopic dermatitis.
Current allergy and asthma reports 2006;6(5):384-9.
2006: Fonacier Luz; Charlesworth Ernest N; Spergel Jonathan M; Leung Donald Y M
The black box warning for topical calcineurin inhibitors: looking outside the box.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006;97(1):117-20.
2006: Spergel Jonathan M; Leung Donald Y M
Safety of topical calcineurin inhibitors in atopic dermatitis: evaluation of the evidence.
Current allergy and asthma reports 2006;6(4):270-4.
2006: Fiset Pierre-Olivier; Leung Donald Y M; Hamid Qutayba
Immunopathology of atopic dermatitis.
The Journal of allergy and clinical immunology 2006;118(1):287-90.
2006: Homey Bernhard; Steinhoff Martin; Ruzicka Thomas; Leung Donald Y M
Cytokines and chemokines orchestrate atopic skin inflammation.
The Journal of allergy and clinical immunology 2006;118(1):178-89.
2006: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects.
The Journal of allergy and clinical immunology 2006;118(1):170-7.
2006: Akdis Cezmi A; Akdis Mübeccel; Bieber Thomas; Bindslev-Jensen Carsten; Boguniewicz Mark; Eigenmann Philippe; Hamid Qutayba; Kapp Alexander; Leung Donald Y M; Lipozencic Jasna; Luger Thomas A; Muraro Antonella; Novak Natalija; Platts-Mills Thomas A E; Rosenwasser Lanny; Scheynius Annika; Simons F Estelle R; Spergel Jonathan; Turjanmaa Kristiina; Wahn Ulrich; Weidinger Stefan; Werfel Thomas; Zuberbier Torsten;
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report.
The Journal of allergy and clinical immunology 2006;118(1):152-69.
2006: Boguniewicz Mark; Schmid-Grendelmeier Peter; Leung Donald Y M
Atopic dermatitis.
The Journal of allergy and clinical immunology 2006;118(1):40-3.
2006: Poole Jill A; Barriga Kathy; Leung Donald Y M; Hoffman Michelle; Eisenbarth George S; Rewers Marian; Norris Jill M
Timing of initial exposure to cereal grains and the risk of wheat allergy.
Pediatrics 2006;117(6):2175-82.
2006: Liu Andrew H; Leung Donald Y M
Renaissance of the hygiene hypothesis.
The Journal of allergy and clinical immunology 2006;117(5):1063-6.
2006: Howell Michael D; Wollenberg Andreas; Gallo Richard L; Flaig Michael; Streib Joanne E; Wong Cathy; Pavicic Tatjana; Boguniewicz Mark; Leung Donald Y M
Cathelicidin deficiency predisposes to eczema herpeticum.
The Journal of allergy and clinical immunology 2006;117(4):836-41.
2006: Li Ling-Bo; Leung Donald Y M; Hall Clifton F; Goleva Elena
Divergent expression and function of glucocorticoid receptor beta in human monocytes and T cells.
Journal of leukocyte biology 2006;79(4):818-27.
2006: Howell Michael D; Gallo Richard L; Boguniewicz Mark; Jones James F; Wong Cathy; Streib Joanne E; Leung Donald Y M
Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus.
Immunity 2006;24(3):341-8.
2006: Cardona Ivan D; Goleva Elena; Ou Liang-Shiou; Leung Donald Y M
Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes.
The Journal of allergy and clinical immunology 2006;117(3):688-95.
2006: Goleva Elena; Li Ling-Bo; Eves P Taylor; Strand Matthew J; Martin Richard J; Leung Donald Y M
Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma.
American journal of respiratory and critical care medicine 2006;173(6):607-16.
2006: Bilsborough Janine; Leung Donald Y M; Maurer Mark; Howell Michael; Boguniewicz Mark; Yao Lena; Storey Harold; LeCiel Cosette; Harder Brandon; Gross Jane A
IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis.
The Journal of allergy and clinical immunology 2006;117(2):418-25.
2006: Boguniewicz Mark; Leung Donald Y M
10. Atopic dermatitis.
The Journal of allergy and clinical immunology 2006;117(2 Suppl Mini-Primer):S475-80.
2006: Shearer William T; Leung Donald Y M
Preface to the 2006 Mini-Primer on Allergic and Immunologic Diseases.
The Journal of allergy and clinical immunology 2006;117(2 Suppl Mini-Primer):S429.
2006: Szefler Stanley J; Whelan Glenn J; Leung Donald Y M
"Black box" warning: wake-up call or overreaction?
The Journal of allergy and clinical immunology 2006;117(1):26-9.
2006: Cardona Ivan D; Cho Sang Hyun; Leung Donald Y M
Role of bacterial superantigens in atopic dermatitis : implications for future therapeutic strategies.
American journal of clinical dermatology 2006;7(5):273-9.
2005: Bender Bruce G; Leung Donald Y M
Sleep disorders in patients with asthma, atopic dermatitis, and allergic rhinitis.
The Journal of allergy and clinical immunology 2005;116(6):1200-1.
2005: Goleva Elena; Cardona Ivan D; Ou Liang-Shiou; Leung Donald Y M
Factors that regulate naturally occurring T regulatory cell-mediated suppression.
The Journal of allergy and clinical immunology 2005;116(5):1094-100.
2005: Howell Michael D; Novak Natalija; Bieber Thomas; Pastore Saveria; Girolomoni Giampiero; Boguniewicz Mark; Streib Joanne; Wong Cathy; Gallo Richard L; Leung Donald Y M
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis.
The Journal of investigative dermatology 2005;125(4):738-45.
2005: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects.
The Journal of allergy and clinical immunology 2005;116(1):153-63.
2005: Fonacier Luz; Spergel Jonathan; Charlesworth Ernest N; Weldon David; Beltrani Vincent; Bernhisel-Broadbent Jan; Boguniewicz Mark; Leung Donald Y M;
Report of the Topical Calcineurin Inhibitor Task Force of the American College of Allergy, Asthma and Immunology and the American Academy of Allergy, Asthma and Immunology.
The Journal of allergy and clinical immunology 2005;115(6):1249-53.
2005: Novak Natalija; Leung Donald Y M
Diet and allergy: you are what you eat?
The Journal of allergy and clinical immunology 2005;115(6):1235-7.
2005: Braff Marissa H; Hawkins Mi'i A; Di Nardo Anna; Lopez-Garcia Belen; Howell Michael D; Wong Cathy; Lin Kenneth; Streib Joanne E; Dorschner Robert; Leung Donald Y M; Gallo Richard L
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4271-8.
2005: Federico Monica J; Covar Ronina A; Brown Eleanor E; Leung Donald Y M; Spahn Joseph D
Racial differences in T-lymphocyte response to glucocorticoids.
Chest 2005;127(2):571-8.
2005: Ou Liang-Shiou; Leung Donald Y M
Advances in atopic dermatitis.
Chang Gung medical journal 2005;28(1):1-8.
2005: Colice Gene L; Stampone Patti; Leung Donald Y M; Szefler Stanley J
Oral corticosteroids in poorly controlled asthma.
The Journal of allergy and clinical immunology 2005;115(1):200-1.
2005: Nomura Ichiro; Abe Jun; Noma Seiji; Saito Hirohisa; Gao Bifeng; Wheeler Gary; Leung Donald Y M
Adrenomedullin is highly expressed in blood monocytes associated with acute Kawasaki disease: a microarray gene expression study.
Pediatric research 2005;57(1):49-55.
2004: Li Ling-bo; Goleva Elena; Hall Clifton F; Ou Liang-Shiou; Leung Donald Y M
Superantigen-induced corticosteroid resistance of human T cells occurs through activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK-ERK) pathway.
The Journal of allergy and clinical immunology 2004;114(5):1059-69.
2004: Busse William W; Leung Donald Y M
New series: Perspectives in asthma.
The Journal of allergy and clinical immunology 2004;114(5):1022.
2004: Leung Donald Y M; Nicklas Richard A; Li James T; Bernstein I Leonard; Blessing-Moore Joann; Boguniewicz Mark; Chapman Jean A; Khan David A; Lang David; Lee Rufus E; Portnoy Jay M; Schuller Diane E; Spector Sheldon L; Tilles Stephen A
Disease management of atopic dermatitis: an updated practice parameter. Joint Task Force on Practice Parameters.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2004;93(3 Suppl 2):S1-21.
2004: Leo Harvey L; Bender Bruce G; Leung Susan B; Tran Zung Vu; Leung Donald Y M
Effect of pimecrolimus cream 1% on skin condition and sleep disturbance in children with atopic dermatitis.
The Journal of allergy and clinical immunology 2004;114(3):691-3.
2004: Goleva Elena; Dunlap Annegret; Leung Donald Y m
Differential control of TH1 versus TH2 cell responses by the combination of low-dose steroids with beta2-adrenergic agonists.
The Journal of allergy and clinical immunology 2004;114(1):183-91.
2004: Sicherer Scott H; Leung Donald Y M
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insect stings.
The Journal of allergy and clinical immunology 2004;114(1):118-24.
2004: Xu Qing; Goleva Elena; Ou Liang-Shiou; Li Ling-Bo; Leung Donald Y M
CD56+ cells induce steroid resistance in B cells exposed to IL-15.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7110-5.
2004: Fakhri Samer; Tulic Meri; Christodoulopoulos Pota; Fukakusa Motonori; Frenkiel Saul; Leung Donald Y M; Hamid Qutayba A
Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model.
The Laryngoscope 2004;114(5):887-92.
2004: Ou Liang-Shiou; Goleva Elena; Hall Clifton; Leung Donald Y M
T regulatory cells in atopic dermatitis and subversion of their activity by superantigens.
The Journal of allergy and clinical immunology 2004;113(4):756-63.
2004: Leung Donald Y M; Boguniewicz Mark; Howell Michael D; Nomura Ichiro; Hamid Qutayba A
New insights into atopic dermatitis.
The Journal of clinical investigation 2004;113(5):651-7.
2004: Howell Michael D; Jones James F; Kisich Kevin O; Streib Joanne E; Gallo Richard L; Leung Donald Y M
Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1763-7.
2004: Leung Donald Y M; Shanahan William R; Li Xiu-Min; Sampson Hugh A
New approaches for the treatment of anaphylaxis.
Novartis Foundation symposium 2004;257():248-60; discussion 260-4, 276-85.
2003: Fakhri Samer; Christodoulopoulos Pota; Tulic Meri; Fukakusa Moto; Frenkiel Saul; Leung Donald Y M; Hamid Qutayba A
Role of microbial toxins in the induction of glucocorticoid receptor beta expression in an explant model of rhinosinusitis.
The Journal of otolaryngology 2003;32(6):388-93.
2003: Leung Donald Y M; Shanahan William R; Sampson Hugh A
Response to "effect of anti-IgE therapy in patients with food allergy".
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;91(6):515-7.
2003: Nomura Ichiro; Gao Bifeng; Boguniewicz Mark; Darst Marc A; Travers Jeffrey B; Leung Donald Y m
Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis: a gene microarray analysis.
The Journal of allergy and clinical immunology 2003;112(6):1195-202.
2003: Novak Natalija; Bieber Thomas; Leung Donald Y M
Immune mechanisms leading to atopic dermatitis.
The Journal of allergy and clinical immunology 2003;112(6 Suppl):S128-39.
2003: Leung Donald Y M
Preface to atopic dermatitis intervention to control the atopic march.
The Journal of allergy and clinical immunology 2003;112(6 Suppl):S117.
2003: Leung Donald Y M; Jain Neal; Leo Harvey L
New concepts in the pathogenesis of atopic dermatitis.
Current opinion in immunology 2003;15(6):634-8.
2003: Nomura Ichiro; Goleva Elena; Howell Michael D; Hamid Quatyba A; Ong Peck Y; Hall Clifton F; Darst Marc A; Gao Bifeng; Boguniewicz Mark; Travers Jeffrey B; Leung Donald Y M
Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3262-9.
2003: Meissner H Cody; Leung Donald Y M
Kawasaki syndrome: where are the answers?
Pediatrics 2003;112(3 Pt 1):672-6.
2003: Leung Donald Y M
Infection in atopic dermatitis.
Current opinion in pediatrics 2003;15(4):399-404.
2003: Leung Donald Y M; Bock S Allan
Progress in peanut allergy research: are we closer to a cure?
The Journal of allergy and clinical immunology 2003;112(1):12-4.
2003: Xu Qing; Leung Donald Y M; Kisich Kevin O
Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils.
The Journal of biological chemistry 2003;278(29):27112-8.
2003: Travers Jeffrey B; Leung Donald Y M; Johnson Christopher; Schlievert Patrick; Marques Mariangela; Cosgrove Jason; Clay Keith L
Augmentation of staphylococcal alpha-toxin signaling by the epidermal platelet-activating factor receptor.
The Journal of investigative dermatology 2003;120(5):789-94.
2003: Orwin Paul M; Fitzgerald J Ross; Leung Donald Y M; Gutierrez Juan A; Bohach Gregory A; Schlievert Patrick M
Characterization of Staphylococcus aureus enterotoxin L.
Infection and immunity 2003;71(5):2916-9.
2003: Toda Masao; Leung Donald Y M; Molet Sophie; Boguniewicz Mark; Taha Rame; Christodoulopoulos Pota; Fukuda Takeshi; Elias Jack A; Hamid Qutayba A
Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions.
The Journal of allergy and clinical immunology 2003;111(4):875-81.
2003: Bender Bruce G; Leung Susan B; Leung Donald Y M
Actigraphy assessment of sleep disturbance in patients with atopic dermatitis: an objective life quality measure.
The Journal of allergy and clinical immunology 2003;111(3):598-602.
2003: Leung Donald Y M; Sampson Hugh A; Yunginger John W; Burks A Wesley; Schneider Lynda C; Wortel Cornelis H; Davis Frances M; Hyun John D; Shanahan William R;
Effect of anti-IgE therapy in patients with peanut allergy.
The New England journal of medicine 2003;348(11):986-93.
2003: Leung Donald Y M; Boguniewicz Mark
Advances in allergic skin diseases.
The Journal of allergy and clinical immunology 2003;111(3 Suppl):S805-12.
2003: Eichenfield Lawrence F; Hanifin Jon M; Beck Lisa A; Lemanske Robert F; Sampson Hugh A; Weiss Scott T; Leung Donald Y M
Atopic dermatitis and asthma: parallels in the evolution of treatment.
Pediatrics 2003;111(3):608-16.
2003: Leung Donald Y M; Bloom John W
Update on glucocorticoid action and resistance.
The Journal of allergy and clinical immunology 2003;111(1):3-22; quiz 23.
2003: Leung Donald Y M; Bieber Thomas
Atopic dermatitis.
Lancet 2003;361(9352):151-60.
2002: Ong Peck Y; Leung Donald Y M
The chemokine receptor CCR6 identifies interferon-gamma expressing T cells and is decreased in atopic dermatitis as compared with psoriasis.
The Journal of investigative dermatology 2002;119(6):1463-4.
2002: Smoot Laura M; McCormick John K; Smoot James C; Hoe Nancy P; Strickland Ian; Cole Robert L; Barbian Kent D; Earhart Cathleen A; Ohlendorf Douglas H; Veasy L George; Hill Harry R; Leung Donald Y M; Schlievert Patrick M; Musser James M
Characterization of two novel pyrogenic toxin superantigens made by an acute rheumatic fever clone of Streptococcus pyogenes associated with multiple disease outbreaks.
Infection and immunity 2002;70(12):7095-104.
2002: Orwin Paul M; Leung Donald Y M; Tripp Timothy J; Bohach Gregory A; Earhart Cathleen A; Ohlendorf Douglas H; Schlievert Patrick M
Characterization of a novel staphylococcal enterotoxin-like superantigen, a member of the group V subfamily of pyrogenic toxins.
Biochemistry 2002;41(47):14033-40.
2002: Goleva Elena; Kisich Kevin O; Leung Donald Y M
A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5934-40.
2002: Ong Peck Y; Ohtake Takaaki; Brandt Corinne; Strickland Ian; Boguniewicz Mark; Ganz Tomas; Gallo Richard L; Leung Donald Y M
Endogenous antimicrobial peptides and skin infections in atopic dermatitis.
The New England journal of medicine 2002;347(15):1151-60.
2002: Engler Renata J M; Kenner Julie; Leung Donald Y M
Smallpox vaccination: Risk considerations for patients with atopic dermatitis.
The Journal of allergy and clinical immunology 2002;110(3):357-65.
2002: Hauk Pia J; Goleva Elena; Strickland Ian; Vottero Alessandra; Chrousos George P; Kisich Kevin O; Leung Donald Y M
Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype.
American journal of respiratory cell and molecular biology 2002;27(3):361-7.
2002: Leung Donald Y M; Spahn Joseph D; Szefler Stanley J
Steroid-unresponsive asthma.
Seminars in respiratory and critical care medicine 2002;23(4):387-98.
2002: Beres Stephen B; Sylva Gail L; Barbian Kent D; Lei Benfang; Hoff Jessica S; Mammarella Nicole D; Liu Meng-Yao; Smoot James C; Porcella Stephen F; Parkins Larye D; Campbell David S; Smith Todd M; McCormick John K; Leung Donald Y M; Schlievert Patrick M; Musser James M
Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10078-83.
2002: Leung Donald Y M; Meissner H Cody; Shulman Stanford T; Mason Wilbert H; Gerber Michael A; Glode Mary P; Myones Barry L; Wheeler J Gary; Ruthazer Robin; Schlievert Patrick M
Prevalence of superantigen-secreting bacteria in patients with Kawasaki disease.
The Journal of pediatrics 2002;140(6):742-6.
2002: Leung Donald Y m; Hopper Nancy
Learning from the past and looking to the future.
The Journal of allergy and clinical immunology 2002;109(1):22-3.
2002: Ong Peck Y; Hamid Qutayba A; Travers Jeffrey B; Strickland Ian; Al Kerithy Muhamed; Boguniewicz Mark; Leung Donald Y M
Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):505-10.
2002: Ong Peck Y; Leung Donald Y M
Atopic dermatitis.
Clinical allergy and immunology 2002;16():355-79.
2001: Travers J B; Norris D A; Leung D Y
The keratinocyte as a target for staphylococcal bacterial toxins.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2001;6(3):225-30.
2001: Boguniewicz M; Leung D Y
Pathophysiologic mechanisms in atopic dermatitis.
Seminars in cutaneous medicine and surgery 2001;20(4):217-25.
2001: Spahn J D; Fost D A; Covar R; Martin R J; Brown E E; Szefler S J; Leung D Y
Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001;87(6):501-5.
2001: Klinnert M D; Nelson H S; Price M R; Adinoff A D; Leung D Y; Mrazek D A
Onset and persistence of childhood asthma: predictors from infancy.
Pediatrics 2001;108(4):E69.
2001: Cho S H; Strickland I; Boguniewicz M; Leung D Y
Fibronectin and fibrinogen contribute to the enhanced binding of Staphylococcus aureus to atopic skin.
The Journal of allergy and clinical immunology 2001;108(2):269-74.
2001: Leung D Y
Atopic dermatitis and the immune system: the role of superantigens and bacteria.
Journal of the American Academy of Dermatology 2001;45(1 Suppl):S13-6.
2001: Cho S H; Strickland I; Tomkinson A; Fehringer A P; Gelfand E W; Leung D Y
Preferential binding of Staphylococcus aureus to skin sites of Th2-mediated inflammation in a murine model.
The Journal of investigative dermatology 2001;116(5):658-63.
2001: Gereda J E; Klinnert M D; Price M R; Leung D Y; Liu A H
Metropolitan home living conditions associated with indoor endotoxin levels.
The Journal of allergy and clinical immunology 2001;107(5):790-6.
2001: Kraft M; Hamid Q; Chrousos G P; Martin R J; Leung D Y
Decreased steroid responsiveness at night in nocturnal asthma. Is the macrophage responsible?
American journal of respiratory and critical care medicine 2001;163(5):1219-25.
2001: Strickland I; Kisich K; Hauk P J; Vottero A; Chrousos G P; Klemm D J; Leung D Y
High constitutive glucocorticoid receptor beta in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids.
The Journal of experimental medicine 2001;193(5):585-93.
2001: McCormick J K; Pragman A A; Stolpa J C; Leung D Y; Schlievert P M
Functional characterization of streptococcal pyrogenic exotoxin J, a novel superantigen.
Infection and immunity 2001;69(3):1381-8.
2001: Leung D Y; Soter N A
Cellular and immunologic mechanisms in atopic dermatitis.
Journal of the American Academy of Dermatology 2001;44(1 Suppl):S1-S12.
2001: Orwin P M; Leung D Y; Donahue H L; Novick R P; Schlievert P M
Biochemical and biological properties of Staphylococcal enterotoxin K.
Infection and immunity 2001;69(1):360-6.
2000: Jirapongsananuruk O; Melamed I; Leung D Y
Additive immunosuppressive effects of 1,25-dihydroxyvitamin D3 and corticosteroids on TH1, but not TH2, responses.
The Journal of allergy and clinical immunology 2000;106(5):981-5.
2000: Yarwood J M; Leung D Y; Schlievert P M
Evidence for the involvement of bacterial superantigens in psoriasis, atopic dermatitis, and Kawasaki syndrome.
FEMS microbiology letters 2000;192(1):1-7.
2000: Covar R A; Leung D Y; McCormick D; Steelman J; Zeitler P; Spahn J D
Risk factors associated with glucocorticoid-induced adverse effects in children with severe asthma.
The Journal of allergy and clinical immunology 2000;106(4):651-9.
2000: Christodoulopoulos P; Leung D Y; Elliott M W; Hogg J C; Muro S; Toda M; Laberge S; Hamid Q A
Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma.
The Journal of allergy and clinical immunology 2000;106(3):479-84.
2000: Gereda J E; Leung D Y; Thatayatikom A; Streib J E; Price M R; Klinnert M D; Liu A H
Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma.
Lancet 2000;355(9216):1680-3.
2000: Taha R A; Minshall E M; Leung D Y; Boguniewicz M; Luster A; Muro S; Toda M; Hamid Q A
Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis.
The Journal of allergy and clinical immunology 2000;105(5):1002-7.
2000: Leung D Y
Atopic dermatitis: new insights and opportunities for therapeutic intervention.
The Journal of allergy and clinical immunology 2000;105(5):860-76.
2000: Hauk P J; Hamid Q A; Chrousos G P; Leung D Y
Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens.
The Journal of allergy and clinical immunology 2000;105(4):782-7.
2000: Leung D Y; Meissner H C
The many faces of Kawasaki syndrome.
Hospital practice (1995) 2000;35(1):77-81, 85-6, 91-4.
2000: Jirapongsananuruk O; Donahue H L; Trumble A E; Leung D Y
The modulation of cytokine and IgE production by tumor necrosis factor-beta in atopic dermatitis.
The Journal of investigative dermatology 2000;114(1):200-3.
1999: Travers J B; Hamid Q A; Norris D A; Kuhn C; Giorno R C; Schlievert P M; Farmer E R; Leung D Y
Epidermal HLA-DR and the enhancement of cutaneous reactivity to superantigenic toxins in psoriasis.
The Journal of clinical investigation 1999;104(9):1181-9.
1999: Jirapongsananuruk O; Leung D Y
The modulation of B7.2 and B7.1 on B cells by immunosuppressive agents.
Clinical and experimental immunology 1999;118(1):1-8.
1999: Leung D Y
Pathogenesis of atopic dermatitis.
The Journal of allergy and clinical immunology 1999;104(3 Pt 2):S99-108.
1999: Wann E R; Fehringer A P; Ezepchuk Y V; Schlievert P M; Bina P; Reiser R F; Höök M M; Leung D Y
Staphylococcus aureus isolates from patients with Kawasaki disease express high levels of protein A.
Infection and immunity 1999;67(9):4737-43.
1999: Hong S J; Michael J G; Fehringer A; Leung D Y
Pepsin-digested peanut contains T-cell epitopes but no IgE epitopes.
The Journal of allergy and clinical immunology 1999;104(2 Pt 1):473-8.
1999: Wamboldt F S; Spahn J D; Klinnert M D; Wamboldt M Z; Gavin L A; Szefler S J; Leung D Y
Clinical outcomes of steroid-insensitive asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1999;83(1):55-60.
1999: Hauk P J; Wenzel S E; Trumble A E; Szefler S J; Leung D Y
Increased T-cell receptor vbeta8+ T cells in bronchoalveolar lavage fluid of subjects with poorly controlled asthma: a potential role for microbial superantigens.
The Journal of allergy and clinical immunology 1999;104(1):37-45.
1999: Fost D A; Leung D Y; Martin R J; Brown E E; Szefler S J; Spahn J D
Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy.
The Journal of allergy and clinical immunology 1999;103(6):1031-5.
1999: Bratton D L; May K R; Kailey J M; Doherty D E; Leung D Y
Staphylococcal toxic shock syndrome toxin-1 inhibits monocyte apoptosis.
The Journal of allergy and clinical immunology 1999;103(5 Pt 1):895-900.
1999: Hamid Q A; Wenzel S E; Hauk P J; Tsicopoulos A; Wallaert B; Lafitte J J; Chrousos G P; Szefler S J; Leung D Y
Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma.
American journal of respiratory and critical care medicine 1999;159(5 Pt 1):1600-4.
1999: Lanz M J; Leung D Y; White C W
Comparison of exhaled nitric oxide to spirometry during emergency treatment of asthma exacerbations with glucocorticoids in children.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1999;82(2):161-4.
1999: Strickland I; Hauk P J; Trumble A E; Picker L J; Leung D Y
Evidence for superantigen involvement in skin homing of T cells in atopic dermatitis.
The Journal of investigative dermatology 1999;112(2):249-53.
1999: Hofer M F; Harbeck R J; Schlievert P M; Leung D Y
Staphylococcal toxins augment specific IgE responses by atopic patients exposed to allergen.
The Journal of investigative dermatology 1999;112(2):171-6.
1999: Kraft M; Vianna E; Martin R J; Leung D Y
Nocturnal asthma is associated with reduced glucocorticoid receptor binding affinity and decreased steroid responsiveness at night.
The Journal of allergy and clinical immunology 1999;103(1 Pt 1):66-71.
1999: Leung D Y
Therapeutic perspectives in atopic dermatitis.
Allergy 1999;54 Suppl 58():39-42.
1999: Ezepchuk Y V; Fehringer A P; Harbeck R; Freed J H; Leung D Y
Staphylococcus aureus isolated from Kawasaki disease patients hyper-releases extracellular protein A.
Molekuliarnaia genetika, mikrobiologiia i virusologiia 1999;(2):29-34.
1998: Leung D Y; Hauk P; Strickland I; Travers J B; Norris D A
The role of superantigens in human diseases: therapeutic implications for the treatment of skin diseases.
The British journal of dermatology 1998;139 Suppl 53():17-29.
1998: Chu H W; Halliday J L; Martin R J; Leung D Y; Szefler S J; Wenzel S E
Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease.
American journal of respiratory and critical care medicine 1998;158(6):1936-44.
1998: Laberge S; Ghaffar O; Boguniewicz M; Center D M; Leung D Y; Hamid Q
Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis.
The Journal of allergy and clinical immunology 1998;102(4 Pt 1):645-50.
1998: Taha R A; Leung D Y; Ghaffar O; Boguniewicz M; Hamid Q
In vivo expression of cytokine receptor mRNA in atopic dermatitis.
The Journal of allergy and clinical immunology 1998;102(2):245-50.
1998: Nimmagadda S R; Spahn J D; Nelson H S; Jenkins J; Szefler S J; Leung D Y
Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1998;81(1):35-40.
1998: Chan M T; Leung D Y; Szefler S J; Spahn J D
Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma.
The Journal of allergy and clinical immunology 1998;101(5):594-601.
1998: Jirapongsananuruk O; Hofer M F; Trumble A E; Norris D A; Leung D Y
Enhanced expression of B7.2 (CD86) in patients with atopic dermatitis: a potential role in the modulation of IgE synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4622-7.
1998: Leung D Y
Molecular basis of allergic diseases.
Molecular genetics and metabolism 1998;63(3):157-67.
1998: Leung D Y; Szefler S J
New insights into steroid resistant asthma.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 1998;9(1):3-12.
1998: Hofer M F; Jirapongsananuruk O; Trumble A E; Leung D Y
Upregulation of B7.2, but not B7.1, on B cells from patients with allergic asthma.
The Journal of allergy and clinical immunology 1998;101(1 Pt 1):96-102.
1997: Minshall E M; Cameron L; Lavigne F; Leung D Y; Hamilos D; Garcia-Zepada E A; Rothenberg M; Luster A D; Hamid Q
Eotaxin mRNA and protein expression in chronic sinusitis and allergen-induced nasal responses in seasonal allergic rhinitis.
American journal of respiratory cell and molecular biology 1997;17(6):683-90.
1997: Lanz M J; Leung D Y; McCormick D R; Harbeck R; Szefler S J; White C W
Comparison of exhaled nitric oxide, serum eosinophilic cationic protein, and soluble interleukin-2 receptor in exacerbations of pediatric asthma.
Pediatric pulmonology 1997;24(5):305-11.
1997: Leung D Y
Immunologic basis of chronic allergic diseases: clinical messages from the laboratory bench.
Pediatric research 1997;42(5):559-68.
1997: Leung D Y; Hamid Q; Vottero A; Szefler S J; Surs W; Minshall E; Chrousos G P; Klemm D J
Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta.
The Journal of experimental medicine 1997;186(9):1567-74.
1997: Wenzel S E; Szefler S J; Leung D Y; Sloan S I; Rex M D; Martin R J
Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):737-43.
1997: Minshall E M; Leung D Y; Martin R J; Song Y L; Cameron L; Ernst P; Hamid Q
Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma.
American journal of respiratory cell and molecular biology 1997;17(3):326-33.
1997: Leung D Y; Hanifin J M; Charlesworth E N; Li J T; Bernstein I L; Berger W E; Blessing-Moore J; Fineman S; Lee F E; Nicklas R A; Spector S L
Disease management of atopic dermatitis: a practice parameter. Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. Work Group on Atopic Dermatitis.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1997;79(3):197-211.
1997: Leung D Y; Sullivan K E; Brown-Whitehorn T F; Fehringer A P; Allen S; Finkel T H; Washington R L; Makida R; Schlievert P M
Association of toxic shock syndrome toxin-secreting and exfoliative toxin-secreting Staphylococcus aureus with Kawasaki syndrome complicated by coronary artery disease.
Pediatric research 1997;42(3):268-72.
1997: Jirapongsananuruk O; Leung D Y
Clinical applications of cytokines: new directions in the therapy of atopic diseases.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1997;79(1):5-16; quiz 19-20.
1997: Norris D A; Travers J B; Leung D Y
Lymphocyte activation in the pathogenesis of psoriasis.
The Journal of investigative dermatology 1997;109(1):1-4.
1997: Folzenlogen D; Hofer M F; Leung D Y; Freed J H; Newell M K
Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients.
Clinical immunology and immunopathology 1997;83(3):199-204.
1997: Naseer T; Minshall E M; Leung D Y; Laberge S; Ernst P; Martin R J; Hamid Q
Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy.
American journal of respiratory and critical care medicine 1997;155(3):845-51.
1997: Leung D Y
Atopic dermatitis: immunobiology and treatment with immune modulators.
Clinical and experimental immunology 1997;107 Suppl 1():25-30.
1997: Gavin L A; Lanz M J; Leung D Y; Roesler T A
Chronic subungual hematomas: a presumed immunologic puzzle resolved with a diagnosis of child abuse.
Archives of pediatrics & adolescent medicine 1997;151(1):103-5.
1996: Spahn J D; Landwehr L P; Nimmagadda S; Surs W; Leung D Y; Szefler S J
Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma.
The Journal of allergy and clinical immunology 1996;98(6 Pt 1):1073-9.
1996: Meer S; Groothuis J R; Harbeck R; Liu S; Leung D Y
The potential role of gastroesophageal reflux in the pathogenesis of food-induced wheezing.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 1996;7(4):167-70.
1996: Spahn J D; Leung D Y
The role of glucocorticoids in the management of asthma.
Allergy and asthma proceedings : the official journal of regional and state allergy societies 1996;17(6):341-50.
1996: Nimmagadda S R; Spahn J D; Leung D Y; Szefler S J
Steroid-resistant asthma: evaluation and management.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 1996;77(5):345-55; quiz 355-6.
1996: Hamilos D L; Leung D Y; Wood R; Bean D K; Song Y L; Schotman E; Hamid Q
Eosinophil infiltration in nonallergic chronic hyperplastic sinusitis with nasal polyposis (CHS/NP) is associated with endothelial VCAM-1 upregulation and expression of TNF-alpha.
American journal of respiratory cell and molecular biology 1996;15(4):443-50.
1996: Ezepchuk Y V; Leung D Y; Middleton M H; Bina P; Reiser R; Norris D A
Staphylococcal toxins and protein A differentially induce cytotoxicity and release of tumor necrosis factor-alpha from human keratinocytes.
The Journal of investigative dermatology 1996;107(4):603-9.
1996: Paterson R L; Lack G; Domenico J M; Delespesse G; Leung D Y; Finkel T H; Gelfand E W
Triggering through CD40 promotes interleukin-4-induced CD23 production and enhanced soluble CD23 release in atopic disease.
European journal of immunology 1996;26(9):1979-84.
1996: Spahn J D; Szefler S J; Surs W; Doherty D E; Nimmagadda S R; Leung D Y
A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2654-9.
1996: Lack G; Bradley K L; Hamelmann E; Renz H; Loader J; Leung D Y; Larsen G; Gelfand E W
Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1432-9.
1996: Leung D Y; Spahn J D; Nimmagadda S R; Szefler S J
Induction of corticosteroid resistance in vitro.
American journal of respiratory and critical care medicine 1996;154(2 Pt 2):S34-7; discussion S37-8.
1996: Makida R; Hofer M F; Takase K; Cambier J C; Leung D Y
Bacterial superantigens induce V beta-specific T cell receptor internalization.
Molecular immunology 1996;33(10):891-900.
1996: Hamid Q; Naseer T; Minshall E M; Song Y L; Boguniewicz M; Leung D Y
In vivo expression of IL-12 and IL-13 in atopic dermatitis.
The Journal of allergy and clinical immunology 1996;98(1):225-31.
1996: Walsh P; Norris D A; Abe J; Martin D K; Giorno R; Leung D Y
Candida albicans induces selective expansion of human T lymphocytes expressing the T-cell receptor variable region V beta 5.1.
Journal of dermatological science 1996;12(2):140-6.
1996: Hofer M F; Newell K; Duke R C; Schlievert P M; Freed J H; Leung D Y
Differential effects of staphylococcal toxic shock syndrome toxin-1 on B cell apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5425-30.
1996: Leung D Y
Kawasaki syndrome: immunomodulatory benefit and potential toxin neutralization by intravenous immune globulin.
Clinical and experimental immunology 1996;104 Suppl 1():49-54.
1996: Saloga J; Leung D Y; Reardon C; Giorno R C; Born W; Gelfand E W
Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T-cell-dependent inflammatory response.
The Journal of investigative dermatology 1996;106(5):982-8.
1996: Boguniewicz M; Leung D Y
New concepts in atopic dermatitis.
Comprehensive therapy 1996;22(3):144-51.
1996: Leung D Y
Superantigens related to Kawasaki syndrome.
Springer seminars in immunopathology 1996;17(4):385-96.
1995: Hofer M F; Lester M R; Schlievert P M; Leung D Y
Upregulation of IgE synthesis by staphylococcal toxic shock syndrome toxin-1 in peripheral blood mononuclear cells from patients with atopic dermatitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1995;25(12):1218-27.
1995: Lester M R; Hofer M F; Renz H; Trumble A E; Gelfand E W; Leung D Y
Modulatory effects of staphylococcal superantigen TSST-1 on IgE synthesis in atopic dermatitis.
Clinical immunology and immunopathology 1995;77(3):332-8.
1995: Leung D Y; Meissner C; Fulton D; Schlievert P M
The potential role of bacterial superantigens in the pathogenesis of Kawasaki syndrome.
Journal of clinical immunology 1995;15(6 Suppl):11S-17S.
1995: Leung D Y; Giorno R C; Kazemi L V; Flynn P A; Busse J B
Evidence for superantigen involvement in cardiovascular injury due to Kawasaki syndrome.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):5018-21.
1995: Leung D Y; Travers J B; Giorno R; Norris D A; Skinner R; Aelion J; Kazemi L V; Kim M H; Trumble A E; Kotb M
Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis.
The Journal of clinical investigation 1995;96(5):2106-12.
1995: Leung D Y; Meissner H C; Fulton D R; Quimby F; Schlievert P M
Superantigens in Kawasaki syndrome.
Clinical immunology and immunopathology 1995;77(2):119-26.
1995: Hamilos D L; Leung D Y; Wood R; Cunningham L; Bean D K; Yasruel Z; Schotman E; Hamid Q
Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis.
The Journal of allergy and clinical immunology 1995;96(4):537-44.
1995: Clayton M H; Leung D Y; Surs W; Szefler S J
Altered glucocorticoid receptor binding in atopic dermatitis.
The Journal of allergy and clinical immunology 1995;96(3):421-3.
1995: Leung D Y
Atopic dermatitis: the skin as a window into the pathogenesis of chronic allergic diseases.
The Journal of allergy and clinical immunology 1995;96(3):302-18; quiz 319.
1995: Leung D Y; Travers J B; Norris D A
The role of superantigens in skin disease.
The Journal of investigative dermatology 1995;105(1 Suppl):37S-42S.
1995: Spahn J D; Leung D Y; Surs W; Harbeck R J; Nimmagadda S; Szefler S J
Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation.
American journal of respiratory and critical care medicine 1995;151(6):1709-14.
1995: Lester M R; Hofer M F; Gately M; Trumble A; Leung D Y
Down-regulating effects of IL-4 and IL-10 on the IFN-gamma response in atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):6174-81.
1995: Dorion B J; Leung D Y
Selective expansion of T cells expressing V beta 2 in peanut allergy.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 1995;6(2):95-7.
1995: Boguniewicz M; Leung D Y
Hypersensitivity reactions to antibiotics commonly used in children.
The Pediatric infectious disease journal 1995;14(3):221-31.
1995: Leung D Y; Gately M; Trumble A; Ferguson-Darnell B; Schlievert P M; Picker L J
Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production.
The Journal of experimental medicine 1995;181(2):747-53.
1995: Abernathy-Carver K J; Sampson H A; Picker L J; Leung D Y
Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen.
The Journal of clinical investigation 1995;95(2):913-8.
1995: Boguniewicz M; Martin R J; Martin D; Gibson U; Celniker A; Williams M; Leung D Y
The effects of nebulized recombinant interferon-gamma in asthmatic airways.
The Journal of allergy and clinical immunology 1995;95(1 Pt 1):133-5.
1995: Bratton D L; Hamid Q; Boguniewicz M; Doherty D E; Kailey J M; Leung D Y
Granulocyte macrophage colony-stimulating factor contributes to enhanced monocyte survival in chronic atopic dermatitis.
The Journal of clinical investigation 1995;95(1):211-8.
1995: Leung D Y; Martin R J; Szefler S J; Sher E R; Ying S; Kay A B; Hamid Q
Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma.
The Journal of experimental medicine 1995;181(1):33-40.
1994: Saloga J; Lack G; Bradley K; Renz H; Larsen G; Leung D Y; Gelfand E W
Inhibition of the development of immediate hypersensitivity by staphylococcal enterotoxin B.
European journal of immunology 1994;24(12):3140-7.
1994: Abernathy-Carver K J; Fan L L; Boguniewicz M; Larsen G L; Leung D Y
Legionella and Pneumocystis pneumonias in asthmatic children on high doses of systemic steroids.
Pediatric pulmonology 1994;18(3):135-8.
1994: Zieg G; Lack G; Harbeck R J; Gelfand E W; Leung D Y
In vivo effects of glucocorticoids on IgE production.
The Journal of allergy and clinical immunology 1994;94(2 Pt 1):222-30.
1994: Leung D Y
Mechanisms of the human allergic response. Clinical implications.
Pediatric clinics of North America 1994;41(4):727-43.
1994: Hamid Q; Boguniewicz M; Leung D Y
Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis.
The Journal of clinical investigation 1994;94(2):870-6.
1994: Kamada A K; Spahn J D; Surs W; Brown E; Leung D Y; Szefler S J
Coexistence of glucocorticoid receptor and pharmacokinetic abnormalities: factors that contribute to a poor response to treatment with glucocorticoids in children with asthma.
The Journal of pediatrics 1994;124(6):984-6.
1994: Picker L J; Martin R J; Trumble A; Newman L S; Collins P A; Bergstresser P R; Leung D Y
Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites.
European journal of immunology 1994;24(6):1269-77.
1994: Finkel T H; Török T J; Ferguson P J; Durigon E L; Zaki S R; Leung D Y; Harbeck R J; Gelfand E W; Saulsbury F T; Hollister J R
Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent?
Lancet 1994;343(8908):1255-8.
1994: Lack G; Renz H; Saloga J; Bradley K L; Loader J; Leung D Y; Larsen G; Gelfand E W
Nebulized but not parenteral IFN-gamma decreases IgE production and normalizes airways function in a murine model of allergen sensitization.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2546-54.
1994: Renz H; Brodie C; Bradley K; Leung D Y; Gelfand E W
Enhancement of IgE production by anti-CD40 antibody in atopic dermatitis.
The Journal of allergy and clinical immunology 1994;93(3):658-68.
1994: Dorion B J; Burks A W; Harbeck R; Williams L W; Trumble A; Helm R M; Leung D Y
The production of interferon-gamma in response to a major peanut allergy, Ara h II correlates with serum levels of IgE anti-Ara h II.
The Journal of allergy and clinical immunology 1994;93(1 Pt 1):93-9.
1994: Sher E R; Leung D Y; Surs W; Kam J C; Zieg G; Kamada A K; Szefler S J
Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy.
The Journal of clinical investigation 1994;93(1):33-9.
1993: Leung D Y
Role of IgE in atopic dermatitis.
Current opinion in immunology 1993;5(6):956-62.
1993: Martin R J; Boguniewicz M; Henson J E; Celniker A C; Williams M; Giorno R C; Leung D Y
The effects of inhaled interferon gamma in normal human airways.
The American review of respiratory disease 1993;148(6 Pt 1):1677-82.
1993: Leung D Y; Meissner H C; Fulton D R; Murray D L; Kotzin B L; Schlievert P M
Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome.
Lancet 1993;342(8884):1385-8.
1993: Kam J C; Szefler S J; Surs W; Sher E R; Leung D Y
Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3460-6.
1993: Boguniewicz M; Schneider L C; Milgrom H; Newell D; Kelly N; Tam P; Izu A E; Jaffe H S; Bucalo L R; Leung D Y
Treatment of steroid-dependent asthma with recombinant interferon-gamma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1993;23(9):785-90.
1993: Leung D Y; Harbeck R; Bina P; Reiser R F; Yang E; Norris D A; Hanifin J M; Sampson H A
Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens.
The Journal of clinical investigation 1993;92(3):1374-80.
1993: Hamilos D L; Leung D Y; Wood R; Meyers A; Stephens J K; Barkans J; Meng Q; Cunningham L; Bean D K; Kay A B
Chronic hyperplastic sinusitis: association of tissue eosinophilia with mRNA expression of granulocyte-macrophage colony-stimulating factor and interleukin-3.
The Journal of allergy and clinical immunology 1993;92(1 Pt 1):39-48.
1993: Jujo K; Renz H; Abe J; Trumble A; Gelfand E W; Leung D Y
Pokeweed mitogen induces IgE synthesis in the presence of a blocking antibody to the interferon-gamma receptor.
The Journal of allergy and clinical immunology 1993;91(6):1206-16.
1993: Leung D Y; Walsh P; Giorno R; Norris D A
A potential role for superantigens in the pathogenesis of psoriasis.
The Journal of investigative dermatology 1993;100(3):225-8.
1993: Abe J; Kotzin B L; Meissner C; Melish M E; Takahashi M; Fulton D; Romagne F; Malissen B; Leung D Y
Characterization of T cell repertoire changes in acute Kawasaki disease.
The Journal of experimental medicine 1993;177(3):791-6.
1993: Hanifin J M; Schneider L C; Leung D Y; Ellis C N; Jaffe H S; Izu A E; Bucalo L R; Hirabayashi S E; Tofte S J; Cantu-Gonzales G
Recombinant interferon gamma therapy for atopic dermatitis.
Journal of the American Academy of Dermatology 1993;28(2 Pt 1):189-97.
1993: Leung D Y
Kawasaki disease.
Current opinion in rheumatology 1993;5(1):41-50.
1993: Kotzin B L; Leung D Y; Kappler J; Marrack P
Superantigens and their potential role in human disease.
Advances in immunology 1993;54():99-166.
1993: Leung D Y
The immunologic basis of atopic dermatitis.
Clinical reviews in allergy 1993;11(4):447-69.
1992: Renz H; Jujo K; Bradley K L; Domenico J; Gelfand E W; Leung D Y
Enhanced IL-4 production and IL-4 receptor expression in atopic dermatitis and their modulation by interferon-gamma.
The Journal of investigative dermatology 1992;99(4):403-8.
1992: Kamada A K; Leung D Y; Gleason M C; Hill M R; Szefler S J
High-dose systemic glucocorticoid therapy in the treatment of severe asthma: a case of resistance and patterns of response.
The Journal of allergy and clinical immunology 1992;90(4 Pt 1):685-7.
1992: Renz H; Or R; Domenico J; Leung D Y; Gelfand E W
Reciprocal regulatory effects of IL-4 on cell growth and immunoglobulin production in Ig-secreting human B-cell lines.
Clinical immunology and immunopathology 1992;64(3):233-41.
1992: Jujo K; Renz H; Abe J; Gelfand E W; Leung D Y
Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis.
The Journal of allergy and clinical immunology 1992;90(3 Pt 1):323-31.
1992: Oppenheimer J J; Nelson H S; Bock S A; Christensen F; Leung D Y
Treatment of peanut allergy with rush immunotherapy.
The Journal of allergy and clinical immunology 1992;90(2):256-62.
1992: Li S H; Chan S C; Toshitani A; Leung D Y; Hanifin J M
Synergistic effects of interleukin 4 and interferon-gamma on monocyte phosphodiesterase activity.
The Journal of investigative dermatology 1992;99(1):65-70.
1992: Abe J; Kotzin B L; Jujo K; Melish M E; Glode M P; Kohsaka T; Leung D Y
Selective expansion of T cells expressing T-cell receptor variable regions V beta 2 and V beta 8 in Kawasaki disease.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4066-70.
1992: Alvarez J; Surs W; Leung D Y; Iklé D; Gelfand E W; Szefler S J
Steroid-resistant asthma: immunologic and pharmacologic features.
The Journal of allergy and clinical immunology 1992;89(3):714-21.
1992: Boguniewicz M; Leung D Y
Management of the patient with allergic reactions to antibiotics.
Pediatric pulmonology 1992;12(2):113-22.
1992: Polla B S; Ezekowitz R A; Leung D Y
Monocytes from patients with atopic dermatitis are primed for superoxide production.
The Journal of allergy and clinical immunology 1992;89(2):545-51.
1992: Leung D Y
The immunoregulatory effects of IVIG in Kawasaki disease and other autoimmune diseases.
Clinical reviews in allergy 1992;10(1-2):93-104.
1992: Leung D Y
Immunopathology of atopic dermatitis.
Springer seminars in immunopathology 1992;13(3-4):427-40.
1991: Leung D Y
The potential role of cytokine-mediated vascular endothelial activation in the pathogenesis of Kawasaki disease.
Acta paediatrica Japonica; Overseas edition 1991;33(6):739-44.
1991: Kamada M M; Twarog F; Leung D Y
Multiple antibiotic sensitivity in a pediatric population.
Allergy proceedings : the official journal of regional and state allergy societies 1991;12(5):347-50.
1991: Leung D Y
Immune mechanisms in atopic dermatitis and relevance to treatment.
Allergy proceedings : the official journal of regional and state allergy societies 1991;12(5):339-46.
1991: Abe J; Forrester J; Nakahara T; Lafferty J A; Kotzin B L; Leung D Y
Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3747-50.
1991: Leung D Y; Pober J S; Cotran R S
Expression of endothelial-leukocyte adhesion molecule-1 in elicited late phase allergic reactions.
The Journal of clinical investigation 1991;87(5):1805-9.
1991: Leung D Y; Kelly C P; Boguniewicz M; Pothoulakis C; LaMont J T; Flores A
Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin.
The Journal of pediatrics 1991;118(4 ( Pt 1)):633-7.
1991: Leung D Y
New developments in Kawasaki disease.
Current opinion in rheumatology 1991;3(1):46-55.
1990: Leung D Y
Immunologic aspects of Kawasaki syndrome.
The Journal of rheumatology. Supplement 1990;24():15-8.
1990: Leung D Y; Hirsch R L; Schneider L; Moody C; Takaoka R; Li S H; Meyerson L A; Mariam S G; Goldstein G; Hanifin J M
Thymopentin therapy reduces the clinical severity of atopic dermatitis.
The Journal of allergy and clinical immunology 1990;85(5):927-33.
1990: Boguniewicz M; Jaffe H S; Izu A; Sullivan M J; York D; Geha R S; Leung D Y
Recombinant gamma interferon in treatment of patients with atopic dermatitis and elevated IgE levels.
The American journal of medicine 1990;88(4):365-70.
1990: Sundel R; Leung D Y
Kawasaki disease.
Current opinion in rheumatology 1990;2(1):81-6.
1990: Burns J C; Huang A S; Newburger J W; Reinhart A L; Walsh M M; Hoch S; Leung D Y
Characterization of the polymerase activity associated with cultured peripheral blood mononuclear cells from patients with Kawasaki disease.
Pediatric research 1990;27(2):109-12.
1989: Leung D Y; Cotran R S; Kurt-Jones E; Burns J C; Newburger J W; Pober J S
Endothelial cell activation and high interleukin-1 secretion in the pathogenesis of acute Kawasaki disease.
Lancet 1989;2(8675):1298-302.
1989: Leung D Y
Immunomodulation by intravenous immune globulin in Kawasaki disease.
The Journal of allergy and clinical immunology 1989;84(4 Pt 2):588-93; discussion 593-4.
1989: Leung D Y
The immunologic effects of IVIG in Kawasaki disease.
International reviews of immunology 1989;5(2):197-202.
1989: Leung D Y
Clinical and immunologic aspects of Kawasaki disease.
Immunodeficiency reviews 1989;1(3):261-71.
1989: Geha R S; Leung D Y
Hyper immunoglobulin E syndrome.
Immunodeficiency reviews 1989;1(2):155-72.
1989: Leung D Y; Cotran R S; Kurt-Jones E; Burns J C; Newburger J W; Pober J S
Endothelial activation in the pathogenesis of Kawasaki disease.
Transactions of the Association of American Physicians 1989;102():131-8.
1988: Brosius C L; Newburger J W; Burns J C; Hojnowski-Diaz P; Zierler S; Leung D Y
Increased prevalence of atopic dermatitis in Kawasaki disease.
The Pediatric infectious disease journal 1988;7(12):863-6.
1988: Leung D Y; Moake J L; Havens P L; Kim M; Pober J S
Lytic anti-endothelial cell antibodies in haemolytic-uraemic syndrome.
Lancet 1988;2(8604):183-6.
1988: Leung D Y; Geha R S
Clinical and immunologic aspects of the hyperimmunoglobulin E syndrome.
Hematology/oncology clinics of North America 1988;2(1):81-100.
1987: Leung D Y
Immunologic abnormalities in Kawasaki syndrome.
Progress in clinical and biological research 1987;250():159-65.

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