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Francis Lévi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Bouchahda Mohamed; Adam René; Giacchetti Sylvie; Castaing Denis; Brezault-Bonnet Catherine; Hauteville Dominique; Innominato Pasquale F; Focan Christian; Machover David; Lévi Francis
Rescue chemotherapy using multidrug chronomodulated hepatic arterial infusion for patients with heavily pretreated metastatic colorectal cancer.
Iurisci Ida; Filipski Elisabeth; Sallam Hatem; Harper Francis; Guettier Catherine; Maire Irène; Hassan Moustapha; Iacobelli Stefano; Lévi Francis
Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib.
Innominato Pasquale F; Focan Christian; Gorlia Thierry; Moreau Thierry; Garufi Carlo; Waterhouse Jim; Giacchetti Sylvie; Coudert Bruno; Iacobelli Stefano; Genet Dominique; Tampellini Marco; Chollet Philippe; Lentz Marie-Ange; Mormont Marie-Christine; Lévi Francis; Bjarnason Georg A;
Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer.

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All Publications

2009: Bouchahda Mohamed; Adam René; Giacchetti Sylvie; Castaing Denis; Brezault-Bonnet Catherine; Hauteville Dominique; Innominato Pasquale F; Focan Christian; Machover David; Lévi Francis
Rescue chemotherapy using multidrug chronomodulated hepatic arterial infusion for patients with heavily pretreated metastatic colorectal cancer.
Cancer 2009;115(21):4990-9.
2009: Iurisci Ida; Filipski Elisabeth; Sallam Hatem; Harper Francis; Guettier Catherine; Maire Irène; Hassan Moustapha; Iacobelli Stefano; Lévi Francis
Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib.
Chronobiology international 2009;26(6):1169-88.
2009: Innominato Pasquale F; Focan Christian; Gorlia Thierry; Moreau Thierry; Garufi Carlo; Waterhouse Jim; Giacchetti Sylvie; Coudert Bruno; Iacobelli Stefano; Genet Dominique; Tampellini Marco; Chollet Philippe; Lentz Marie-Ange; Mormont Marie-Christine; Lévi Francis; Bjarnason Georg A;
Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer.
Cancer research 2009;69(11):4700-7.
2009: Adam René; Wicherts Dennis A; de Haas Robbert J; Ciacio Oriana; Lévi Francis; Paule Bernard; Ducreux Michel; Azoulay Daniel; Bismuth Henri; Castaing Denis
Patients with initially unresectable colorectal liver metastases: is there a possibility of cure?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(11):1829-35.
2009: Altinok Atilla; Lévi Francis; Goldbeter Albert
Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;36(1):20-38.
2008: Lévi Francis; Altinok Atilla; Clairambault Jean; Goldbeter Albert
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2008;366(1880):3575-98.
2008: Guillaumond Fabienne; Lacoche Samuel; Dulong Sandrine; Grechez-Cassiau Aline; Filipski Elisabeth; Li Xiao-Mei; Lévi Francis; Berra Edurne; Delaunay Franck; Teboul Michèle
Altered Stra13 and Dec2 circadian gene expression in hypoxic cells.
Biochemical and biophysical research communications 2008;369(4):1184-9.
2008: Efficace Fabio; Innominato Pasquale F; Bjarnason Georg; Coens Corneel; Humblet Yves; Tumolo Salvatore; Genet Dominique; Tampellini Marco; Bottomley Andrew; Garufi Carlo; Focan Christian; Giacchetti Sylvie; Lévi Francis;
Validation of patient's self-reported social functioning as an independent prognostic factor for survival in metastatic colorectal cancer patients: results of an international study by the Chronotherapy Group of the European Organisation for Research and Treatment of Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(12):2020-6.
2008: Dulong Sandrine; Delaunay Franck; Lévi Francis
[Circadian control of muscle transcriptome]
Médecine sciences : M/S 2008;24(4):372-4.
2008: Adam René; Wicherts Dennis A; de Haas Robbert J; Aloia Thomas; Lévi Francis; Paule Bernard; Guettier Catherine; Kunstlinger Francis; Delvart Valérie; Azoulay Daniel; Castaing Denis
Complete pathologic response after preoperative chemotherapy for colorectal liver metastases: myth or reality?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(10):1635-41.
2007: Adam René; Aloia Thomas; Lévi Francis; Wicherts Dennis A; de Haas Robbert J; Paule Bernard; Bralet Marie-Pierre; Bouchahda Mohamed; Machover David; Ducreux Michel; Castagne Vincent; Azoulay Daniel; Castaing Denis
Hepatic resection after rescue cetuximab treatment for colorectal liver metastases previously refractory to conventional systemic therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(29):4593-602.
2007: Lévi Francis; Focan Christian; Karaboué Abdoulaye; de la Valette Virginie; Focan-Henrard Danielle; Baron Benoît; Kreutz Françoise; Giacchetti Sylvie
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics.
Advanced drug delivery reviews 2007;59(9-10):1015-35.
2007: Iurisci Ida; Rich Tyvin; Lévi Francis; Innominato Pasquale F; Tinari Nicola; Irtelli Luciana; De Tursi Michele; Grassadonia Antonino; Iacobelli Stefano
Relief of symptoms after gefitinib is associated with improvement of rest/activity rhythm in advanced lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(16):e17-9.
2007: Focan C; Lévi F; Innominato P
[Circadian behaviour of host versus tumour outcome. A review]
Pathologie-biologie 2007;55(3-4):178-80.
2007: Teboul M; Barrat-Petit M-A; Li X-M; Claustrat B; Formento J-L; Milano G; Lévi F; Delaunay F
[Circadian clock gene expression in human peripheral blood mononuclear cells]
Pathologie-biologie 2007;55(3-4):208-10.
2007: Beau J; Iurisci I; Beau T; Lévi F
[Dynamic circadian system patients under chimiotherapy]
Pathologie-biologie 2007;55(3-4):171-5.
2006: Gholam Dany; Giacchetti Sylvie; Brézault-Bonnet Catherine; Bouchahda Mohamed; Hauteville Dominique; Adam René; Ducot Béatrice; Ghémard Odile; Kustlinger Francis; Jasmin Claude; Lévi Francis
Chronomodulated irinotecan, oxaliplatin, and leucovorin-modulated 5-Fluorouracil as ambulatory salvage therapy in patients with irinotecan- and oxaliplatin-resistant metastatic colorectal cancer.
The oncologist 2006;11(10):1072-80.
2006: Iurisci Ida; Filipski Elisabeth; Reinhardt Jens; Bach Stéphane; Gianella-Borradori Athos; Iacobelli Stefano; Meijer Laurent; Lévi Francis
Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor.
Cancer research 2006;66(22):10720-8.
2006: Aloia Thomas; Sebagh Mylène; Plasse Marylène; Karam Vincent; Lévi Francis; Giacchetti Sylvie; Azoulay Daniel; Bismuth Henri; Castaing Denis; Adam René
Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(31):4983-90.
2006: Tsinkalovsky Oleg; Filipski Elisabeth; Rosenlund Benedikte; Sothern Robert B; Eiken Hans Geir; Wu Ming Wei; Claustrat Bruno; Bayer Jan; Lévi Francis; Laerum Ole Didrik
Circadian expression of clock genes in purified hematopoietic stem cells is developmentally regulated in mouse bone marrow.
Experimental hematology 2006;34(9):1249-61.
2006: Giacchetti Sylvie; Bjarnason Georg; Garufi Carlo; Genet Dominique; Iacobelli Stefano; Tampellini Marco; Smaaland Rune; Focan Christian; Coudert Bruno; Humblet Yves; Canon Jean Luc; Adenis Antoine; Lo Re Giovanni; Carvalho Carlos; Schueller Johannes; Anciaux Nicole; Lentz Marie-Ange; Baron Benoît; Gorlia Thierry; Lévi Francis;
Phase III trial comparing 4-day chronomodulated therapy versus 2-day conventional delivery of fluorouracil, leucovorin, and oxaliplatin as first-line chemotherapy of metastatic colorectal cancer: the European Organisation for Research and Treatment of Cancer Chronotherapy Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(22):3562-9.
2006: Filipski Elizabeth; Li Xiaoi Mei; Lévi Francis
Disruption of circadian coordination and malignant growth.
Cancer causes & control : CCC 2006;17(4):509-14.
2005: Teboul Michèle; Barrat-Petit Marie-Audrey; Li Xiao Mei; Claustrat Bruno; Formento Jean-Louis; Delaunay Franck; Lévi Francis; Milano Gérard
Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells.
Journal of molecular medicine (Berlin, Germany) 2005;83(9):693-9.
2005: Beau J; Delaunay F; Lacoche S; Gréchez-Cassiau A; Lévi F
[Algorithm of determination of circadian gene expression profiles analysed with DNA microarrays]
Pathologie-biologie 2005;53(5):295-9.
2005: Li X M; Tanaka K; Sun J; Filipski E; Kayitalire L; Focan C; Lévi F
Preclinical relevance of dosing time for the therapeutic index of gemcitabine-cisplatin.
British journal of cancer 2005;92(9):1684-9.
2005: Filipski Elisabeth; Innominato Pasquale F; Wu MingWei; Li Xiao-Mei; Iacobelli Stefano; Xian Li-Jian; Lévi Francis
Effects of light and food schedules on liver and tumor molecular clocks in mice.
Journal of the National Cancer Institute 2005;97(7):507-17.
2005: Rich Tyvin; Innominato Pasquale F; Boerner Julie; Mormont M Christine; Iacobelli Stefano; Baron Benoit; Jasmin Claude; Lévi Francis
Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1757-64.
2005: Sebagh M; Plasse M; Lévi F; Adam René
Severe hepatic sinusoidal obstruction and oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer: a real entity?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(2):331; author reply 332-3.
2005: Granda Teresa G; Liu Xu-Hui; Smaaland Rune; Cermakian Nicolas; Filipski Elisabeth; Sassone-Corsi Paolo; Lévi Francis
Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):304-6.
2005: Zeng Zhao-Lei; Sun Jian; Guo Ling; Li Su; Wu Ming-wei; Qiu Fang; Jiang Wen-qi; Lévi Francis; Xian Li-jian
Circadian rhythm in dihydropyrimidine dehydrogenase activity and reduced glutathione content in peripheral blood of nasopharyngeal carcinoma patients.
Chronobiology international 2005;22(4):741-54.
2004: Li X M; Beau J; Delagrange P; Mocaër E; Lévi F
Circadian rhythm entrainment with melatonin, melatonin receptor antagonist S22153 or their combination in mice exposed to constant light.
Journal of pineal research 2004;37(3):176-84.
2004: Filipski Elisabeth; King Verdun M; Etienne Marie-Christine; Li XiaoMei; Claustrat Bruno; Granda Teresa G; Milano Gérard; Hastings Michael H; Lévi Francis
Persistent twenty-four hour changes in liver and bone marrow despite suprachiasmatic nuclei ablation in mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(4):R844-51.
2004: Filipski Elisabeth; Lemaigre Guy; Liu Xu-Hui; Méry-Mignard Dominique; Mahjoubi Mondher; Lévi Francis
Circadian rhythm of irinotecan tolerability in mice.
Chronobiology international 2004;21(4-5):613-30.
2004: Wu M W; Li X M; Xian L J; Lévi F
Effects of meal timing on tumor progression in mice.
Life sciences 2004;75(10):1181-93.
2003: Granda Teresa G; Filipski Elisabeth; Vrignaud P; Bissery M C; Lévi Francis
[Rhythm of expression of BCL-2 protein of MA13/C mammaryadenocarcinoma bearing-mice]
Pathologie-biologie 2003;51(4):220-1.
2003: Filipski Elisabeth; King Verdun M; Li XiaoMei; Granda Teresa G; Mormont Marie-Christine; Claustrat Bruno; Hastings Michael H; Lévi Francis
Disruption of circadian coordination accelerates malignant growth in mice.
Pathologie-biologie 2003;51(4):216-9.
2003: Clairambault Jean; Claude Daniel; Filipski Elisabeth; Granda Teresa; Lévi Francis
[Toxicity and anti-tumour efficacy of oxaliplatin on Glasgow osteosarcoma induced in mice: a mathematical model]
Pathologie-biologie 2003;51(4):212-5.
2003: Coudert B; Bjarnason G; Focan C; di Paola E Donato; Lévi F
It is time for chronotherapy!
Pathologie-biologie 2003;51(4):197-200.
2003: Porsin B; Formento J-L; Filipski E; Etienne M-C; Francoual M; Renée N; Magné N; Lévi F; Milano G
Dihydropyrimidine dehydrogenase circadian rhythm in mouse liver: comparison between enzyme activity and gene expression.
European journal of cancer (Oxford, England : 1990) 2003;39(6):822-8.
2002: Filipski Elisabeth; King Verdun M; Li XiaoMei; Granda Teresa G; Mormont Marie-Christine; Liu XuHui; Claustrat Bruno; Hastings Michael H; Lévi Francis
Host circadian clock as a control point in tumor progression.
Journal of the National Cancer Institute 2002;94(9):690-7.
2002: Granda T G; D'Attino R-M; Filipski E; Vrignaud P; Garufi C; Terzoli E; Bissery M-C; Lévi F
Circadian optimisation of irinotecan and oxaliplatin efficacy in mice with Glasgow osteosarcoma.
British journal of cancer 2002;86(6):999-1005.
2002: Curé H; Chevalier V; Adenis A; Tubiana-Mathieu N; Niezgodzki G; Kwiatkowski F; Pezet D; Perpoint B; Coudert B; Focan C; Lévi F; Chipponi J; Chollet P
Phase II trial of chronomodulated infusion of high-dose fluorouracil and l-folinic acid in previously untreated patients with metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(5):1175-81.
2002: Coudert B; Focan C; Donato di Paola E; Lévi F;
It's time for chronotherapy!
European journal of cancer (Oxford, England : 1990) 2002;38 Suppl 4():S50-3.
2002: Xian Li-Jian; Jian Sun; Cao Qi-Yuan; Ye Yan-Li; Liu Xu-Hui; Li Xiao-Mei; Lévi Francis
Circadian rhythms of DNA synthesis in nasopharyngeal carcinoma cells.
Chronobiology international 2002;19(1):69-76.
2002: Bourin Philippe; Ledain Arnaud F; Beau Jacques; Mille Dominique; Lévi Francis
In-vitro circadian rhythm of murine bone marrow progenitor production.
Chronobiology international 2002;19(1):57-67.
2002: Li Xiao-Mei; Vincenti Marc; Lévi Francis
Pharmacological effects of vinorelbine on body temperature and locomotor activity circadian rhythms in mice.
Chronobiology international 2002;19(1):43-55.
2002: Granda Teresa G; Lévi Francis
Tumor-based rhythms of anticancer efficacy in experimental models.
Chronobiology international 2002;19(1):21-41.
2002: Mormont Marie-Christine; Langouët Anne Marie; Claustrat Bruno; Bogdan André; Marion Sylvie; Waterhouse Jim; Touitou Yvan; Lévi Francis
Marker rhythms of circadian system function: a study of patients with metastatic colorectal cancer and good performance status.
Chronobiology international 2002;19(1):141-55.
2002: Lévi Francis
From circadian rhythms to cancer chronotherapeutics.
Chronobiology international 2002;19(1):1-19.
2001: Bensmaïne M A; Marty M; de Gramont A; Brienza S; Lévi F; Ducreux M; François E; Gamelin E; Bleiberg H; Cvitkovic E
Factors predicting efficacy of oxaliplatin in combination with 5-fluorouracil (5-FU) +/- folinic acid in a compassionate-use cohort of 481 5-FU-resistant advanced colorectal cancer patients.
British journal of cancer 2001;85(4):509-17.
2001: Lévi F; Giacchetti S; Zidani R; Brezault-Bonnet C; Tigaud J M; Goldwasser F; Misset J L
Chronotherapy of colorectal cancer metastases.
Hepato-gastroenterology 2001;48(38):320-2.
2001: Granda T G; Filipski E; D'Attino R M; Vrignaud P; Anjo A; Bissery M C; Lévi F
Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination.
Cancer research 2001;61(5):1996-2001.
2000: Bensmaïne; de Gramont A; Brienza S; Marty M; Lévi F; Ducreux M; François E; Gamelin E; Bleiberg H; Bleuzen P; Simon J; Cvitkovic E
Factors predicting for efficacy of oxaliplatin in combination with 5-fluorouracil (5-FU)+/-folinic acid (FA) in a compassionate-use cohort of 370 5-FU-resistant advanced colorectal cancer (CRC) patients.
European journal of cancer (Oxford, England : 1990) 2000;36(18):2335-43.
2000: Mormont M C; Waterhouse J; Bleuzen P; Giacchetti S; Jami A; Bogdan A; Lellouch J; Misset J L; Touitou Y; Lévi F
Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3038-45.
2000: Garufi C; Brienza S; Pugliese P; Aschelter A M; Bensmaine; Bertheault-Cvitkovic F; Nisticò C; Giunta S; Caterino M; Giannarelli D; Cosimelli M; Lévi F; Terzoli E
Overcoming resistance to chronomodulated 5-fluorouracil and folinic acid by the addition of chronomodulated oxaliplatin in advanced colorectal cancer patients.
Anti-cancer drugs 2000;11(6):495-501.
2000: Li X M; Liu X H; Filipski E; Metzger G; Delagrange P; Jeanniot J P; Lévi F
Relationship of atypical melatonin rhythm with two circadian clock outputs in B6D2F(1) mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(4):R924-30.
2000: Lévi F; Metzger G; Massari C; Milano G
Oxaliplatin: pharmacokinetics and chronopharmacological aspects.
Clinical pharmacokinetics 2000;38(1):1-21.
2000: Giacchetti S; Perpoint B; Zidani R; Le Bail N; Faggiuolo R; Focan C; Chollet P; Llory J F; Letourneau Y; Coudert B; Bertheaut-Cvitkovic F; Larregain-Fournier D; Le Rol A; Walter S; Adam R; Misset J L; Lévi F
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(1):136-47.
2000: Lévi F
Therapeutic implications of circadian rhythms in cancer patients.
Novartis Foundation symposium 2000;227():119-36; discussion 136-42.
1999: Lévi F
Cancer chronotherapy.
The Journal of pharmacy and pharmacology 1999;51(8):891-8.
1999: Giacchetti S; Itzhaki M; Gruia G; Adam R; Zidani R; Kunstlinger F; Brienza S; Alafaci E; Bertheault-Cvitkovic F; Jasmin C; Reynes M; Bismuth H; Misset J L; Lévi F
Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(6):663-9.
1999: Lévi F; Zidani R; Brienza S; Dogliotti L; Perpoint B; Rotarski M; Letourneau Y; Llory J F; Chollet P; Le Rol A; Focan C
A multicenter evaluation of intensified, ambulatory, chronomodulated chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin as initial treatment of patients with metastatic colorectal carcinoma. International Organization for Cancer Chronotherapy.
Cancer 1999;85(12):2532-40.
1999: Filipski E; Amat S; Lemaigre G; Vincenti M; Breillout F; Lévi F A
Relationship between circadian rhythm of vinorelbine toxicity and efficacy in P388-bearing mice.
The Journal of pharmacology and experimental therapeutics 1999;289(1):231-5.
1999: Garufi C; Dogliotti L; Terzoli E; Focan C; Smaaland R; Chollet P; Perpoint B; Lévi F
Tumori. Chronotherapy Study Group of the European Organization for Research and Treatment of Cancer.
Tumori 1999;85(2):149-50.
1999: Li X M; Ezan E; Bindoula G; Soulard C; Liu X H; Deschamps de Paillette E; Lévi F
Chronopharmacologic aspects of continuous AcSDKP infusion in mice.
Experimental hematology 1999;27(1):19-27.
1999: van den Heiligenberg S; Deprés-Brummer P; Barbason H; Claustrat B; Reynes M; Lévi F
The tumor promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Life sciences 1999;64(26):2523-34.
1998: Li X M; Metzger G; Filipski E; Lemaigre G; Lévi F
Modulation of nonprotein sulphydryl compounds rhythm with buthionine sulphoximine: relationship with oxaliplatin toxicity in mice.
Archives of toxicology 1998;72(9):574-9.
1998: Tampellini M; Filipski E; Liu X H; Lemaigre G; Li X M; Vrignaud P; François E; Bissery M C; Lévi F
Docetaxel chronopharmacology in mice.
Cancer research 1998;58(17):3896-904.
1998: Li X M; Filipski E; Lévi F
Pharmacological modulation of cisplatin toxicity rhythms with buthionine sulfoximine in mice bearing pancreatic adenocarcinoma (PO3).
Chronobiology international 1998;15(4):323-35.
1998: Deprés-Brummer P; Metzger G; Lévi F
Pharmacologic restoration of suppressed temperature rhythms in rats by melatonin, melatonin receptor agonist, S20242, or 8-OH-DPAT.
European journal of pharmacology 1998;347(1):57-66.
1998: Li X M; Soulard C; Filipski E; Deschamps de Paillette E; Lévi F
Circadian-based effects of AcSDKP, with or without rhG-CSF on hematologic toxicity of chemotherapy in mice.
European journal of haematology 1998;60(3):181-8.
1997: Deprés-Brummer P; Bourin P; Pages N; Metzger G; Lévi F
Persistent T lymphocyte rhythms despite suppressed circadian clock outputs in rats.
The American journal of physiology 1997;273(6 Pt 2):R1891-9.
1997: Garufi C; Lévi F; Aschelter A M; Pace R; Giunta S; Nisticò C; Gallà D A; Silecchia G F; Franchi F; Narduzzi C; Terzoli E
A phase I trial of 5-day chronomodulated infusion of 5-fluorouracil and 1-folinic acid in patients with metastatic colorectal cancer.
European journal of cancer (Oxford, England : 1990) 1997;33(10):1566-71.
1997: Lévi F; Zidani R; Misset J L
Randomised multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer. International Organization for Cancer Chronotherapy.
Lancet 1997;350(9079):681-6.
1997: Mormont M C; Lévi F
Circadian-system alterations during cancer processes: a review.
International journal of cancer. Journal international du cancer 1997;70(2):241-7.
1996: Bertheault-Cvitkovic F; Jami A; Ithzaki M; Brummer P D; Brienza S; Adam R; Kunstlinger F; Bismuth H; Misset J L; Lévi F
Biweekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil, and leucovorin in patients with metastatic colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(11):2950-8.
1996: Touitou Y; Bogdan A; Lévi F; Benavides M; Auzéby A
Disruption of the circadian patterns of serum cortisol in breast and ovarian cancer patients: relationships with tumour marker antigens.
British journal of cancer 1996;74(8):1248-52.
1996: Lévi F
[Chronopharmacology and chronotherapy of cancers]
Pathologie-biologie 1996;44(7):631-44.
1996: Deprés-Brummer P; Metzger G; Morin D; Urien S; Touitou Y; Tillement J P; Claustrat B; Lévi F
Pharmacokinetically guided melatonin scheduling in rats with circadian system suppression.
European journal of pharmacology 1996;312(2):171-8.
1996: Lévi F
Chronotherapy for gastrointestinal cancers.
Current opinion in oncology 1996;8(4):334-41.
1996: Boughattas N A; Li X M; Filipski J; Lemaigre G; Filipski E; Bouzouita K; Belhadj O; Lévi F
Modulation of cisplatin chronotoxicity related to reduced glutathione in mice.
Human & experimental toxicology 1996;15(7):563-72.
1996: Mormont M C; De Prins J; Lévi F
[Study of circadian rhythms of activity by actometry: preliminary results in 30 patients with metastatic colorectal cancer]
Pathologie-biologie 1996;44(3):165-71.
1996: Deprés-Brummer P; Metzger G; Lévi F
[Analyses of rhythms of the body temperature in free running in rats]
Pathologie-biologie 1996;44(3):150-6.
1995: Lévi F; Giacchetti S; Adam R; Zidani R; Metzger G; Misset J L
Chronomodulation of chemotherapy against metastatic colorectal cancer. International Organization for Cancer Chronotherapy.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1264-70.
1995: Deprés-Brummer P; Lévi F; Metzger G; Touitou Y
Light-induced suppression of the rat circadian system.
The American journal of physiology 1995;268(5 Pt 2):R1111-6.
1995: Perpoint B; Le Bousse-Kerdilès C; Clay D; Smadja-Joffe F; Deprés-Brummer P; Laporte-simitsidis S; Jasmin C; Lévi F
In vitro chronopharmacology of recombinant mouse IL-3, mouse GM-CSF, and human G-CSF on murine myeloid progenitor cells.
Experimental hematology 1995;23(4):362-8.
1995: Lévi F; Soussan A; Adam R; Caussanel J P; Metzger G; Jasmin C; Bismuth H; Smolensky M; Misset J L
A phase I-II trial of five-day continuous intravenous infusion of 5-fluorouracil delivered at circadian rhythm modulated rate in patients with metastatic colorectal cancer.
The Journal of infusional chemotherapy 1995;5(3 Suppl 1):153-8.
1995: Garufi C; Lévi F; Giunta S; Aschelter A; Pace R; Nisticò C; Terzoli E
Chronomodulated 5-day infusion of floxuridine and L-folinic acid in patients with advanced malignancies: a feasibility and tolerability study.
The Journal of infusional chemotherapy 1995;5(3 Suppl 1):134-7.
1995: Touitou Y; Lévi F; Bogdan A; Benavides M; Bailleul F; Misset J L
Rhythm alteration in patients with metastatic breast cancer and poor prognostic factors.
Journal of cancer research and clinical oncology 1995;121(3):181-8.
1994: Boughattas N A; Hecquet B; Fournier C; Bruguerolle B; Trabelsi H; Bouzouita K; Omrane B; Lévi F
Comparative pharmacokinetics of oxaliplatin (L-OHP) and carboplatin (CBDCA) in mice with reference to circadian dosing time.
Biopharmaceutics & drug disposition 1994;15(9):761-73.
1994: Lévi F; Tampellini M; Metzger G; Bizi E; Lemaigre G; Hallek M
Circadian changes in mitoxantrone toxicity in mice: relationship with plasma pharmacokinetics.
International journal of cancer. Journal international du cancer 1994;59(4):543-7.
1994: Lévi F A; Zidani R; Vannetzel J M; Perpoint B; Focan C; Faggiuolo R; Chollet P; Garufi C; Itzhaki M; Dogliotti L
Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: a randomized multi-institutional trial.
Journal of the National Cancer Institute 1994;86(21):1608-17.
1994: Metzger G; Massari C; Etienne M C; Comisso M; Brienza S; Touitou Y; Milano G; Bastian G; Misset J L; Lévi F
Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: relationship with mucosal toxicity in patients with cancer.
Clinical pharmacology and therapeutics 1994;56(2):190-201.
1994: Lévi F
Chronotherapy of cancer: biological basis and clinical application.
Pathologie-biologie 1994;42(4):338-41.
1993: Bertheault-Cvitkovic F; Lévi F; Soussan S; Brienza S; Adam R; Itzhaki M; Misset J L; Bismuth H
Circadian rhythm-modulated chemotherapy with high-dose 5-fluorouracil: a pilot study in patients with pancreatic adenocarcinoma.
European journal of cancer (Oxford, England : 1990) 1993;29A(13):1851-4.
1993: Lévi F; Brienza S; Metzer G; Deprés-Brummer P; Bertheault-Cvitkovic F; Zidani R; Adam R; Misset J L
Implications of chronobiology for 5-fluorouracil (5-FU) efficacy.
Advances in experimental medicine and biology 1993;339():169-83.
1992: Touitou Y; Bogdan A; Auzéby A; Lévi F
The in vitro effect of metyrapone on steroid synthesis in mice adrenals at different circadian stages.
Chronobiology international 1992;9(5):350-5.
1992: Lévi F; Misset J L; Brienza S; Adam R; Metzger G; Itzakhi M; Caussanel J P; Kunstlinger F; Lecouturier S; Descorps-Declère A
A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer.
Cancer 1992;69(4):893-900.
1991: Lévi F; Canon C; Dipalma M; Florentin I; Misset J L
When should the immune clock be reset? From circadian pharmacodynamics to temporally optimized drug delivery.
Annals of the New York Academy of Sciences 1991;618():312-29.
1990: Boughattas N A; Lévi F; Fournier C; Hecquet B; Lemaigre G; Roulon A; Mathé G; Reinberg A
Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice.
The Journal of pharmacology and experimental therapeutics 1990;255(2):672-9.
1990: Caussanel J P; Lévi F; Brienza S; Misset J L; Itzhaki M; Adam R; Milano G; Hecquet B; Mathé G
Phase I trial of 5-day continuous venous infusion of oxaliplatin at circadian rhythm-modulated rate compared with constant rate.
Journal of the National Cancer Institute 1990;82(12):1046-50.
1990: Lévi F; Benavides M; Chevelle C; Le Saunier F; Bailleul F; Misset J L; Regensberg C; Vannetzel J M; Reinberg A; Mathé G
Chemotherapy of advanced ovarian cancer with 4'-O-tetrahydropyranyl doxorubicin and cisplatin: a randomized phase II trial with an evaluation of circadian timing and dose-intensity.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1990;8(4):705-14.
1990: Touitou Y; Bailleul F; Lévi F; Bogdan A; Touitou C; Metzger G; Mechkouri M
Circadian rhythms of tumor markers in breast cancer patients.
Progress in clinical and biological research 1990;341A():59-66.
1989: Boughattas N A; Lévi F; Fournier C; Lemaigre G; Roulon A; Hecquet B; Mathé G; Reinberg A
Circadian rhythm in toxicities and tissue uptake of 1,2-diamminocyclohexane(trans-1)oxalatoplatinum(II) in mice.
Cancer research 1989;49(12):3362-8.
1988: Boughattas N A; Lévi F; Hecquet B; Lemaigre G; Roulon A; Fournier C; Reinberg A
Circadian time dependence of murine tolerance for carboplatin.
Toxicology and applied pharmacology 1988;96(2):233-47.
1988: Lévi F; Blazsek I; Ferlé-Vidovic A
Circadian and seasonal rhythms in murine bone marrow colony-forming cells affect tolerance for the anticancer agent 4'-O-tetrahydropyranyladriamycin (THP).
Experimental hematology 1988;16(8):696-701.
1988: Petit E; Milano G; Lévi F; Thyss A; Bailleul F; Schneider M
Circadian rhythm-varying plasma concentration of 5-fluorouracil during a five-day continuous venous infusion at a constant rate in cancer patients.
Cancer research 1988;48(6):1676-9.
1988: Lévi F A; Canon C; Touitou Y; Reinberg A; Mathé G
Seasonal modulation of the circadian time structure of circulating T and natural killer lymphocyte subsets from healthy subjects.
The Journal of clinical investigation 1988;81(2):407-13.
1988: Lévi F A; Canon C; Touitou Y; Sulon J; Mechkouri M; Ponsart E D; Touboul J P; Vannetzel J M; Mowzowicz I; Reinberg A
Circadian rhythms in circulating T lymphocyte subtypes and plasma testosterone, total and free cortisol in five healthy men.
Clinical and experimental immunology 1988;71(2):329-35.
1986: Lévi F; Bailleul F; Misset J L; Reinberg A; Mathe G
Timing of maintenance chemotherapy for childhood acute lymphoblastic leukaemia.
Lancet 1986;1(8490):1160-1.
1986: Bailleul F; Lévi F; Reinberg A; Mathé G
Interindividual differences in the circadian hematologic time structure of cancer patients.
Chronobiology international 1986;3(1):47-54.
1985: Lévi F; Blum J P; Lemaigre G; Mechkouri M; Roulon A; Mathé G
A histological assessment of the four-day subrenal capsule assay (SRCA).
Annales chirurgiae et gynaecologiae. Supplementum 1985;199():44-50.
1983: Lévi F; Canon C; Blum J P; Reinberg A; Mathé G
Large-amplitude circadian rhythm in helper:suppressor ratio of peripheral blood lymphocytes.
Lancet 1983;2(8347):462-3.

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