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Stewart Levine

Research Profile

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Cuilian Dai; Karen J Keeran; Pradeep K Dagur; J Philip McCoy; Xuan Qu; Alan T Remaley; Xianglan Yao; Zu-Xi Yu; Gayle J Zywicke; Stewart J Levine
Apolipoprotein A-I attenuates ovalbumin-induced neutrophilic airway inflammation via a granulocyte colony-stimulating factor-dependent mechanism.
Karin Fredriksson; Karen J Keeran; Arnold S Kristof; Jonathan K Lam; Katharine S Meyer; Joel Moss; Xuan Qu; Xianglan Yao; Zu-Xi Yu; Gayle J Zywicke; Jill A Fielhaber; Stewart J Levine
Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.
Xianglan Yao; Alan T Remaley; Michael P Vitek; Stewart J Levine
Apolipoprotein mimetic peptides: a new approach for the treatment of asthma.

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All Publications

2012: Cuilian Dai; Karen J Keeran; Pradeep K Dagur; J Philip McCoy; Xuan Qu; Alan T Remaley; Xianglan Yao; Zu-Xi Yu; Gayle J Zywicke; Stewart J Levine
Apolipoprotein A-I attenuates ovalbumin-induced neutrophilic airway inflammation via a granulocyte colony-stimulating factor-dependent mechanism.
American journal of respiratory cell and molecular biology 2012;47(2):186-95.
2012: Karin Fredriksson; Karen J Keeran; Arnold S Kristof; Jonathan K Lam; Katharine S Meyer; Joel Moss; Xuan Qu; Xianglan Yao; Zu-Xi Yu; Gayle J Zywicke; Jill A Fielhaber; Stewart J Levine
Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.
PloS one 2012;7(5):e33984.
2012: Xianglan Yao; Alan T Remaley; Michael P Vitek; Stewart J Levine
Apolipoprotein mimetic peptides: a new approach for the treatment of asthma.
Frontiers in pharmacology 2012;3():37.
2011: Hai-Yan Qi; Sura Alsaaty; Li-Yuan Chen; Mathew P Daniels; Stewart J Levine; Yueqin Liu; James H Shelhamer
A cytosolic phospholipase A2-initiated lipid mediator pathway induces autophagy in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):5286-92.
2011: Xianglan Yao; Alan T Remaley; Stewart J Levine
New kids on the block: the emerging role of apolipoproteins in the pathogenesis and treatment of asthma.
Chest 2011;140(4):1048-54.
2011: Man Yu; Stewart J Levine
Toll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses.
Cytokine & growth factor reviews 2011;22(2):63-72.
2011: Man Yu; Jonathan Lam; Balázs Rada; Thomas L Leto; Stewart J Levine
Double-stranded RNA induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2- and caspase-dependent pathways.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(2):1180-8.
2011: Xianglan Yao; Cuilian Dai; Karin Fredriksson; Pradeep K Dagur; J Philip McCoy; Xuan Qu; Zu-Xi Yu; Karen J Keeran; Gayle J Zywicke; Marcelo J A Amar; Alan T Remaley; Stewart J Levine
5A, an apolipoprotein A-I mimetic peptide, attenuates the induction of house dust mite-induced asthma.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):576-83.
2010: Xianglan Yao; Karin Fredriksson; Zu-Xi Yu; Xiuli Xu; Nalini Raghavachari; Karen J Keeran; Gayle J Zywicke; Minjung Kwak; Marcelo J A Amar; Alan T Remaley; Stewart J Levine
Apolipoprotein E negatively regulates house dust mite-induced asthma via a low-density lipoprotein receptor-mediated pathway.
American journal of respiratory and critical care medicine 2010;182(10):1228-38.
2010: Stewart J Levine; Sally E Wenzel
Narrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes.
Annals of internal medicine 2010;152(4):232-7.
2009: Christopher Looze; David Yui; Lester Leung; Matthew Ingham; Maryann Kaler; Xianglan Yao; Wells W Wu; Rong-Fong Shen; Mathew P Daniels; Stewart J Levine
Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Biochemical and biophysical research communications 2009;378(3):433-8.
2008: Aminul Islam; Heather Jones; Toyoko Hiroi; Jonathan Lam; Jing Zhang; Joel Moss; Martha Vaughan; Stewart J Levine
cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2.
The Journal of biological chemistry 2008;283(37):25364-71.
2008: Barbara Adamik; Aminul Islam; Farshid N Rouhani; Feras I Hawari; Jing Zhang; Stewart J Levine
An association between RBMX, a heterogeneous nuclear ribonucleoprotein, and ARTS-1 regulates extracellular TNFR1 release.
Biochemical and biophysical research communications 2008;371(3):505-9.
2008: Stewart J Levine
Molecular mechanisms of soluble cytokine receptor generation.
The Journal of biological chemistry 2008;283(21):14177-81.
2008: Jing Zhang; Feras I Hawari; Robert D Shamburek; Barbara Adamik; Maryann Kaler; Aminul Islam; Da-Wei Liao; Farshid N Rouhani; Matthew Ingham; Stewart J Levine
Circulating TNFR1 exosome-like vesicles partition with the LDL fraction of human plasma.
Biochemical and biophysical research communications 2008;366(2):579-84.
2008: Souheil El-Chemaly; Stewart J Levine; Joel Moss
Lymphatics in lung disease.
Annals of the New York Academy of Sciences 2008;1131():195-202.
2007: Stewart J Levine
Proteomics of lung cell biology and pulmonary disease.
Expert review of respiratory medicine 2007;1(2):255-69.
2007: Aminul Islam; Xiaoyan Shen; Toyoko Hiroi; Joel Moss; Martha Vaughan; Stewart J Levine
The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles.
The Journal of biological chemistry 2007;282(13):9591-9.
2006: Aminul Islam; Barbara Adamik; Feras I Hawari; Ge Ma; Farshid N Rouhani; Jing Zhang; Stewart J Levine
Extracellular TNFR1 release requires the calcium-dependent formation of a nucleobindin 2-ARTS-1 complex.
The Journal of biological chemistry 2006;281(10):6860-73.
2005: Farshid N Rouhani; Catherine A Meitin; Maryann Kaler; Dianne Miskinis-Hilligoss; Mario Stylianou; Stewart J Levine
Effect of tumor necrosis factor antagonism on allergen-mediated asthmatic airway inflammation.
Respiratory medicine 2005;99(9):1175-82.
2005: Stewart J Levine; Barbara Adamik; Feras I Hawari; Aminul Islam; Zu-Xi Yu; Da-Wei Liao; Jing Zhang; Xinle Cui; Farshid N Rouhani
Proteasome inhibition induces TNFR1 shedding from human airway epithelial (NCI-H292) cells.
American journal of physiology. Lung cellular and molecular physiology 2005;289(2):L233-43.
2005: Caitriona A Buckley; Farshid N Rouhani; Maryann Kaler; Barbara Adamik; Feras I Hawari; Stewart J Levine
Amino-terminal TACE prodomain attenuates TNFR2 cleavage independently of the cysteine switch.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1132-8.
2004: Stewart J Levine
Mechanisms of soluble cytokine receptor generation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5343-8.
2004: Feras I Hawari; Farshid N Rouhani; Xinle Cui; Zu-Xi Yu; Caitriona Buckley; Maryann Kaler; Stewart J Levine
Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1297-302.
2003: Xinle Cui; Farshid N Rouhani; Feras I Hawari; Stewart J Levine
Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6814-9.
2003: Xinle Cui; Farshid N Rouhani; Feras I Hawari; Stewart J Levine
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding.
The Journal of biological chemistry 2003;278(31):28677-85.
2002: Xinle Cui; Feras I Hawari; Sura Alsaaty; Marion Lawrence; Christian A Combs; Weidong Geng; Farshid N Rouhani; Dianne Miskinis; Stewart J Levine
Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding.
The Journal of clinical investigation 2002;110(4):515-26.
2001: D A Russian; Stewart J Levine
Pneumocystis carinii pneumonia in patients without HIV infection.
The American journal of the medical sciences 2001;321(1):56-65.
2001: U Nanavaty; A D Goldstein; Stewart J Levine
Polymorphisms in candidate asthma genes.
The American journal of the medical sciences 2001;321(1):11-6.
1998: Xiang-Lan Yao; Stewart J Levine; Mark J Cowan; Carolea Logun; James H Shelhamer
Tumor necrosis factor-alpha stimulates human Clara cell secretory protein production by human airway epithelial cells.
American journal of respiratory cell and molecular biology 1998;19(4):629-35.
1997: Thomas Benfield; Bettina Lundgren; Stewart J Levine; G Kronborg; J H Shelhamer; Jens D Lundgren
The major surface glycoprotein of Pneumocystis carinii induces release and gene expression of interleukin-8 and tumor necrosis factor alpha in monocytes.
Infection and immunity 1997;65(11):4790-4.
1997: Tiyun Wu; Stewart J Levine; Mark J Cowan; Carolea Logun; CW Angus; James H Shelhamer
Antisense inhibition of 85-kDa cPLA2 blocks arachidonic acid release from airway epithelial cells.
The American journal of physiology 1997;273(2 Pt 1):L331-8.
1997: Mark J Cowan; James H Shelhamer; Stewart J Levine
Acute respiratory failure in the HIV-seropositive patient.
Critical care clinics 1997;13(3):523-52.
1997: Stewart J Levine; T Wu; James H Shelhamer
Extracellular release of the type I intracellular IL-1 receptor antagonist from human airway epithelial cells: differential effects of IL-4, IL-13, IFN-gamma, and corticosteroids.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5949-57.
1996: Stewart J Levine
Pneumocystis carinii.
Clinics in chest medicine 1996;17(4):665-95.
1996: Stewart J Levine; Thomas Benfield; James H Shelhamer
Corticosteroids induce intracellular interleukin-1 receptor antagonist type I expression by a human airway epithelial cell line.
American journal of respiratory cell and molecular biology 1996;15(2):245-51.
1996: Stewart J Levine; Carolea Logun; Dharam Chopra; J S Rhim; James H Shelhamer
Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells.
American journal of respiratory cell and molecular biology 1996;14(3):254-61.
1995: James H Shelhamer; Stewart J Levine; Tiyun Wu; David B Jacoby; M A Kaliner; S I Rennard
NIH conference. Airway inflammation.
Annals of internal medicine 1995;123(4):288-304.
1995: Stewart J Levine
Bronchial epithelial cell-cytokine interactions in airway inflammation.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 1995;43(3):241-9.
1995: Stewart J Levine; P Larivée; Carolea Logun; CW Angus; Frederick P Ognibene; James H Shelhamer
Tumor necrosis factor-alpha induces mucin hypersecretion and MUC-2 gene expression by human airway epithelial cells.
American journal of respiratory cell and molecular biology 1995;12(2):196-204.
1994: P Larivée; Stewart J Levine; A Martinez; Tiyun Wu; Carolea Logun; James H Shelhamer
Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranes.
American journal of respiratory cell and molecular biology 1994;11(2):199-205.
1994: Tiyun Wu; Stewart J Levine; M G Lawrence; Carolea Logun; CW Angus; James H Shelhamer
Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2.
The Journal of clinical investigation 1994;93(2):571-7.
1993: Stewart J Levine; P Larivée; Carolea Logun; CW Angus; James H Shelhamer
Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line.
The American journal of physiology 1993;265(4 Pt 1):L360-8.
1993: J R Dichter; Stewart J Levine; James H Shelhamer
Approach to the immunocompromised host with pulmonary symptoms.
Hematology/oncology clinics of North America 1993;7(4):887-912.
1992: Stewart J Levine; D Kennedy; James H Shelhamer; A Kovacs; IM Feuerstein; Vee J Gill; Frida Stock; D Solomon; C T Boylen; Henry Masur
Diagnosis of Pneumocystis carinii pneumonia by multiple lobe, site-directed bronchoalveolar lavage with immunofluorescent monoclonal antibody staining in human immunodeficiency virus-infected patients receiving aerosolized pentamidine chemoprophylaxis.
The American review of respiratory disease 1992;146(4):838-43.
1992: Stewart J Levine
An approach to the diagnosis of pulmonary infections in immunosuppressed patients.
Seminars in respiratory infections 1992;7(2):81-95.
1991: Stewart J Levine; Henry Masur; Vee J Gill; IM Feuerstein; Anthony F Suffredini; D Brown; H Clifford Lane; R Yarchoan; James H Shelhamer; Frederick P Ognibene
Effect of aerosolized pentamidine prophylaxis on the diagnosis of Pneumocystis carinii pneumonia by induced sputum examination in patients infected with the human immunodeficiency virus.
The American review of respiratory disease 1991;144(4):760-4.
1991: Stewart J Levine; THOMAS WALSH; A Martinez; Peter Q Eichacker; G Lopez-Berestein; Charles Natanson
Cardiopulmonary toxicity after liposomal amphotericin B infusion.
Annals of internal medicine 1991;114(8):664-6.