FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brian Lewis

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Genes, ras

Co-author Network

Publications

TOP 3
Victoria A Appleman; JiuFeng Cai; David S Klimstra; Leanne G Ahronian; Brian C Lewis
KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling.
Mihir Rajurkar; Karl Simin; Lan Xu; Lihua J Zhu; Andrew P McMahon; Victoria A Appleman; Jennifer L Cotton; Wilfredo E De Jesus-Monge; David R Driscoll; He Huang; David S Klimstra; Brian C Lewis; Junhao Mao
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Ya-Wen Chen; Victor Boyartchuk; Brian C Lewis
Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brian Lewis (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Victoria A Appleman; JiuFeng Cai; David S Klimstra; Leanne G Ahronian; Brian C Lewis
KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling.
Molecular cancer research : MCR 2012;10(9):1228-39.
2012: Mihir Rajurkar; Karl Simin; Lan Xu; Lihua J Zhu; Andrew P McMahon; Victoria A Appleman; Jennifer L Cotton; Wilfredo E De Jesus-Monge; David R Driscoll; He Huang; David S Klimstra; Brian C Lewis; Junhao Mao
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):E1038-47.
2009: Ya-Wen Chen; Victor Boyartchuk; Brian C Lewis
Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells.
Neoplasia (New York, N.Y.) 2009;11(9):835-45.
2008: Jennifer P Morton; David S Klimstra; Michelle E Mongeau; Brian C Lewis
Trp53 deletion stimulates the formation of metastatic pancreatic tumors.
The American journal of pathology 2008;172(4):1081-7.
2008: Ya-Wen Chen; Seema Paliwal; Kyle M Draheim; Steven R Grossman; Brian C Lewis
p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.
Cancer research 2008;68(2):476-82.
2007: Yi-Chieh Nancy Du; Brian C Lewis; Douglas Hanahan; Harold Varmus
Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion.
PLoS biology 2007;5(10):e276.
2007: Seema Paliwal; Ramesh Kovi; Bharath Nath; Ya-Wen Chen; Brian C Lewis; Steven R Grossman
The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor.
Cancer research 2007;67(19):9322-9.
2007: Ya-Wen Chen; David S Klimstra; Michelle E Mongeau; Jessica L Tatem; Victor Boyartchuk; Brian C Lewis
Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells.
Cancer research 2007;67(16):7589-96.
2007: Jennifer P Morton; Brian C Lewis
Shh signaling and pancreatic cancer: implications for therapy?
Cell cycle (Georgetown, Tex.) 2007;6(13):1553-7.
2007: Jennifer P Morton; Michelle E Mongeau; David S Klimstra; John P Morris; Yie Chia Lee; Yoshiya Kawaguchi; Christopher V E Wright; Matthias Hebrok; Brian C Lewis
Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5103-8.
2006: Brian C Lewis
Development of the pancreas and pancreatic cancer.
Endocrinology and metabolism clinics of North America 2006;35(2):397-404, xi.
2005: Brian C Lewis; David S Klimstra; Nicholas D Socci; Su Xu; Jason A Koutcher; Harold Varmus
The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma.
Molecular and cellular biology 2005;25(4):1228-37.
2003: Brian C Lewis; David S Klimstra; Harold Varmus
The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer.
Genes & development 2003;17(24):3127-38.
2001: Brian C Lewis; Nachimuthu Chinnasamy; Richard A Morgan; Harold Varmus
Development of an avian leukosis-sarcoma virus subgroup A pseudotyped lentiviral vector.
Journal of virology 2001;75(19):9339-44.
1999: Galen H Fisher; Sandra Orsulic; Eric C Holland; WP Hively; Yi Li; Brian C Lewis; Bart Williams; Harold Varmus
Development of a flexible and specific gene delivery system for production of murine tumor models.
Oncogene 1999;18(38):5253-60.