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Juan Leza

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

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Blotting, Western

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Stress, Psychological

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TOP 3
Karina S MacDowell; José L M Madrigal; Juan A Micó; Mara Parellada; Celso Arango; Borja García-Bueno; Juan C Leza
Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation.
Leyre Urigüen; Esther Berrocoso; E Castro; M Desco; M Ferrer-Alcon; Jesús A García-Sevilla; J Garzón; I Gil-Pisa; M J Guerrero; A Gutiérrez-Adán; Juan C Leza; J L M Madrigal; J A Micó; E Munarriz-Cuezva; J Enrique Ortega; Javier Pascau; A Pazos; B Pintado; P Sánchez-Blázquez; M Luisa Soto Montenegro; J Javier Meana
Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.
Iciar Gárate; Borja Garcia-Bueno; ML Gomez-Lus; Luis Alou; Javier Caso; Jose Luis Muñoz Madrigal; Juan A Micó; Juan C Leza
Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway.

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All Publications

2013: Karina S MacDowell; José L M Madrigal; Juan A Micó; Mara Parellada; Celso Arango; Borja García-Bueno; Juan C Leza
Risperidone normalizes increased inflammatory parameters and restores anti-inflammatory pathways in a model of neuroinflammation.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(1):121-35.
2013: Leyre Urigüen; Esther Berrocoso; E Castro; M Desco; M Ferrer-Alcon; Jesús A García-Sevilla; J Garzón; I Gil-Pisa; M J Guerrero; A Gutiérrez-Adán; Juan C Leza; J L M Madrigal; J A Micó; E Munarriz-Cuezva; J Enrique Ortega; Javier Pascau; A Pazos; B Pintado; P Sánchez-Blázquez; M Luisa Soto Montenegro; J Javier Meana
Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.
Translational psychiatry 2013;3():e221.
2013: Iciar Gárate; Borja Garcia-Bueno; ML Gomez-Lus; Luis Alou; Javier Caso; Jose Luis Muñoz Madrigal; Juan A Micó; Juan C Leza
Stress-induced neuroinflammation: role of the Toll-like receptor-4 pathway.
Biological psychiatry 2013;73(1):32-43.
2012: Marina Díaz-Marsá; Itziar Guemes; Karina S Macdowell; Víctor Rubio; José L Carrasco; Juan C Leza
Activation of the cholinergic anti-inflammatory system in peripheral blood mononuclear cells from patients with borderline personality disorder.
Journal of psychiatric research 2012;46(12):1610-7.
2012: Lucía Márquez; José L M Madrigal; Borja García-Bueno; Juan C Leza
Mangiferin decreases inflammation and oxidative damage in rat brain after stress.
European journal of nutrition 2012;51(6):729-39.
2012: Silvia Zoppi; M Luisa Gómez-Lus; Luis Alou; Javier Caso; Arturo Colón; Borja García-Bueno; José L M Madrigal; Jorge Manzanares; Ignacio Marín-Jiménez; Luis Menchén; Beatriz G Pérez-Nievas; Juan C Leza
Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(5):G565-71.
2012: María S García-Gutiérrez; Juan C Leza; Borja García-Bueno; Silvia Zoppi; Jorge Manzanares
Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors.
British journal of pharmacology 2012;165(4):951-64.
2012: Ana Gonzalez-Pinto; Montserrat Graell-Berna; Juan C Leza; Monica Martinez-Cengotitabengoa; Celso Arango; Immaculada Baeza; Soraya Otero-Cuesta; Cesar A Soutullo; JA Micó
Antioxidant defense system and family environment in adolescents with family history of psychosis.
BMC psychiatry 2012;12():200.
2011: Ara E Hinojosa; Juan C Leza; Borja García-Bueno; José L M Madrigal
Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors.
Brain research bulletin 2011;86(5-6):326-33.
2011: Isabel Martínez-Gras; Beatriz G Pérez-Nievas; Borja García-Bueno; José L M Madrigal; Eva Andrés-Esteban; Roberto Rodríguez-Jiménez; Janet Hoenicka; Tomas Palomo; Gabriel Rubio; Juan C Leza
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia.
Schizophrenia research 2011;128(1-3):15-22.
2011: Cristina González; Esperanza Herradón; Raquel Abalo; Gema Vera; Beatriz G Pérez-Nievas; Juan C Leza; María Isabel Martín; Visitación López-Miranda
Cannabinoid/agonist WIN 55,212-2 reduces cardiac ischaemia–reperfusion injury in Zucker diabetic fatty rats: role of CB2 receptors and iNOS/eNOS.
Diabetes/metabolism research and reviews 2011;27(4):331-40.
2011: Sandra Pérez-Rial; María S García-Gutiérrez; José A Molina; Beatriz G Pérez-Nievas; Catherine Ledent; Carlos Leiva; Juan C Leza; Jorge Manzanares
Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors.
Neurobiology of aging 2011;32(4):631-45.
2011: Silvia Zoppi; Beatriz G Pérez-Nievas; José L M Madrigal; Jorge Manzanares; Juan C Leza; Borja García-Bueno
Regulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(4):805-18.
2011: Iciar Gárate; Borja García-Bueno; Esther Berrocoso; Lidia Bravo; Javier Caso; José L M Madrigal; Juan A Micó; Juan C Leza
Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression.
Journal of neuroinflammation 2011;8():151.
2011: Beatriz G Perez Nievas; Thea Hammerschmidt; Markus P Kummer; Dick Terwel; Juan C Leza; Michael T Heneka
Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice.
Journal of neurochemistry 2011;116(1):43-52.
2010: Borja García-Bueno; Beatriz G Pérez-Nievas; Juan C Leza
Is there a role for the nuclear receptor PPARγ in neuropsychiatric diseases?
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(10):1411-29.
2010: Lucía Márquez; Beatriz G Pérez-Nievas; Icíar Gárate; Borja García-Bueno; José Lm Madrigal; Luis Menchén; Gabino Garrido; Juan C Leza
Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis.
World journal of gastroenterology : WJG 2010;16(39):4922-31.
2010: Jose L M Madrigal; Borja Garcia-Bueno; Ara E Hinojosa; Paul Polak; Douglas L Feinstein; Juan C Leza
Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs.
Journal of neurochemistry 2010;113(2):543-51.
2010: Beatriz G Pérez-Nievas; José L M Madrigal; Borja García-Bueno; Silvia Zoppi; Juan C Leza
Corticosterone basal levels and vulnerability to LPS-induced neuroinflammation in the rat brain.
Brain research 2010;1315():159-68.
2010: Beatriz G Pérez-Nievas; Borja García-Bueno; José L M Madrigal; Juan C Leza
Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated.
Journal of neuroinflammation 2010;7():60.
2009: Pilar Alejandra Saiz; Maria P Garcia-Portilla; Gerardo Florez; Paul Corcoran; Celso Arango; Blanca Morales; Juan C Leza; Sandra Alvarez; Eva M Díaz; Victoria Alvarez; Eliecer Coto; Luis Nogueiras; Julio Bobes
Polymorphisms of the IL-1 gene complex are associated with alcohol dependence in Spanish Caucasians: data from an association study.
Alcoholism, clinical and experimental research 2009;33(12):2147-53.
2009: Javier Caso; Olivia Hurtado; Marta Pereira; Borja García-Bueno; Luis Menchén; Luis Alou; María Luisa Gómez-Lus; Maria Moro; ignacio lizasoain; Juan C Leza
Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;296(4):R979-85.
2009: Jose L M Madrigal; Juan C Leza; Paul Polak; Sergey Kalinin; Douglas L Feinstein
Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(1):263-7.
2008: Borja García-Bueno; Javier Caso; Juan C Leza
Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms.
Neuroscience and biobehavioral reviews 2008;32(6):1136-51.
2008: Javier Caso; Juan C Leza; Luis Menchén
The effects of physical and psychological stress on the gastro-intestinal tract: lessons from animal models.
Current molecular medicine 2008;8(4):299-312.
2008: Juan C Leza; Luis Menchén
Stress-induced deleterious consequences in the gastrointestinal tract.
Current molecular medicine 2008;8(4):244-6.
2008: Raquel Fernández-Durango; Amalia Fernández-Martínez; Julian Garcia-Feijoo; Alfredo Castillo; José Martínez de la Casa; Borja García-Bueno; Beatriz G Pérez-Nievas; Arturo Fernández-Cruz; Juan C Leza
Expression of nitrotyrosine and oxidative consequences in the trabecular meshwork of patients with primary open-angle glaucoma.
Investigative ophthalmology & visual science 2008;49(6):2506-11.
2008: Javier Caso; Jesús M Pradillo; Olivia Hurtado; Juan C Leza; Maria Moro; ignacio lizasoain
Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke.
Stroke; a journal of cerebral circulation 2008;39(4):1314-20.
2008: Borja García-Bueno; José L M Madrigal; Beatriz G Pérez-Nievas; Juan C Leza
Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats.
Endocrinology 2008;149(4):1969-78.
2007: Javier Caso; Maria Moro; Pedro Lorenzo; ignacio lizasoain; Juan C Leza
Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2007;17(9):600-7.
2007: Beatriz G Pérez-Nievas; Borja García-Bueno; Javier Caso; Luis Menchén; Juan C Leza
Corticosterone as a marker of susceptibility to oxidative/nitrosative cerebral damage after stress exposure in rats.
Psychoneuroendocrinology 2007;32(6):703-11.
2007: Borja García-Bueno; Javier Caso; Beatriz G Pérez-Nievas; Pedro Lorenzo; Juan C Leza
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(6):1251-60.
2007: Angel Ponferrada; Javier Caso; Luis Alou; Arturo Colón; David Sevillano; Maria Moro; ignacio lizasoain; Pedro Menchén; María-Luisa Gómez-Lus; Pedro Lorenzo; Enrique Cos; Juan C Leza; Luis Menchén
The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction.
Gastroenterology 2007;132(5):1791-803.
2006: José L M Madrigal; Borja García-Bueno; Javier Caso; Beatriz G Pérez-Nievas; Juan C Leza
Stress-induced oxidative changes in brain.
CNS & neurological disorders drug targets 2006;5(5):561-8.
2006: Javier Caso; ignacio lizasoain; Pedro Lorenzo; Maria Moro; Juan C Leza
The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats.
Neuroscience 2006;142(1):59-69.
2006: Manuel Comabella; Cristina Romera; Montse Camiña; Hector Perkal; Maria Moro; Juan C Leza; ignacio lizasoain; Mireia Castillo; Xavier Montalban
TNF-alpha converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis.
Journal of neurology 2006;253(6):701-6.
2005: Antonio Cárdenas; Maria Moro; Olivia Hurtado; Juan C Leza; ignacio lizasoain
Dual role of nitric oxide in adult neurogenesis.
Brain research. Brain research reviews 2005;50(1):1-6.
2005: Marta Pereira; Olivia Hurtado; Antonio Cárdenas; David Alonso-Escolano; Lisardo Boscá; José Vivancos; Florentino Nombela; Juan C Leza; Pedro Lorenzo; ignacio lizasoain; Maria Moro
The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke.
Journal of neuropathology and experimental neurology 2005;64(9):797-805.
2005: Borja García-Bueno; José L M Madrigal; ignacio lizasoain; Maria Moro; Pedro Lorenzo; Juan C Leza
The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats.
Psychopharmacology 2005;180(3):513-22.
2005: David Fernández-López; José Martínez-Orgado; Ignacio Casanova; Bartolomé Bonet; Juan C Leza; Pedro Lorenzo; Maria Moro; ignacio lizasoain
Immature rat brain slices exposed to oxygen-glucose deprivation as an in vitro model of neonatal hypoxic-ischemic encephalopathy.
Journal of neuroscience methods 2005;145(1-2):205-12.
2005: Borja García-Bueno; José L M Madrigal; ignacio lizasoain; Maria Moro; Pedro Lorenzo; Juan C Leza
Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats.
Biological psychiatry 2005;57(8):885-94.
2005: Fernando J Pérez-Asensio; Olivia Hurtado; María C Burguete; Maria Moro; Juan B Salom; ignacio lizasoain; Germán Torregrosa; Juan C Leza; Enrique Alborch; José Castillo; Richard G Knowles; Pedro Lorenzo
Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia.
Neurobiology of disease 2005;18(2):375-84.
2005: Olivia Hurtado; Maria Moro; Antonio Cárdenas; Verónica Sánchez; Paz Fernández-Tomé; Juan C Leza; Pedro Lorenzo; Julio J Secades; Rafael Lozano; Antoni Dávalos; José Castillo; ignacio lizasoain
Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport.
Neurobiology of disease 2005;18(2):336-45.
2005: Jesús M Pradillo; Cristina Romera; Olivia Hurtado; Antonio Cárdenas; Maria Moro; Juan C Leza; Antoni Dávalos; José Castillo; Pedro Lorenzo; ignacio lizasoain
TNFR1 upregulation mediates tolerance after brain ischemic preconditioning.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(2):193-203.
2004: Arturo Colón; José L M Madrigal; Luis Menchén; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Juan C Leza
Stress increases susceptibility to oxidative/nitrosative mucosal damage in an experimental model of colitis in rats.
Digestive diseases and sciences 2004;49(10):1713-21.
2004: Luis Menchén; Arturo Colón; José L M Madrigal; Luis Beltrán; Sofía Botella; ignacio lizasoain; Juan C Leza; Maria Moro; Pedro Menchén; Enrique Cos; Pedro Lorenzo
Activity of inducible and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis.
The American journal of gastroenterology 2004;99(9):1756-64.
2004: Maria Moro; Antonio Cárdenas; Olivia Hurtado; Juan C Leza; ignacio lizasoain
Role of nitric oxide after brain ischaemia.
Cell calcium 2004;36(3-4):265-75.
2004: Carolina Munhoz; José L M Madrigal; Borja García-Bueno; Jesús M Pradillo; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Cristoforo Scavone; Juan C Leza
TNF-alpha accounts for short-term persistence of oxidative status in rat brain after two weeks of repeated stress.
The European journal of neuroscience 2004;20(4):1125-30.
2004: Cristina Romera; Olivia Hurtado; Sofia H Botella; ignacio lizasoain; Antonio Cárdenas; Paz Fernández-Tomé; Juan C Leza; Pedro Lorenzo; Maria Moro
In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(6):1350-7.
2003: Olivia Hurtado; Javier De Cristóbal; Verónica Sánchez; ignacio lizasoain; Antonio Cárdenas; Marta Pereira; M Isabel Colado; Juan C Leza; Pedro Lorenzo; Maria Moro
Inhibition of glutamate release by delaying ATP fall accounts for neuroprotective effects of antioxidants in experimental stroke.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2082-4.
2003: José L M Madrigal; Borja García-Bueno; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Juan C Leza
Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress.
The European journal of neuroscience 2003;18(6):1701-5.
2003: José L M Madrigal; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Ana Patricia Fernández; José Rodrigo; Lisardo Boscá; Juan C Leza
Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(9):1579-88.
2003: José L M Madrigal; Javier Caso; Javier De Cristóbal; Antonio Cárdenas; Juan C Leza; ignacio lizasoain; Pedro Lorenzo; Maria Moro
Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats.
Brain research 2003;979(1-2):137-45.
2003: Ana Patricia Fernández; David Alonso; Ignacio Lisazoaín; Julia Serrano; Juan C Leza; María Luisa Bentura; Juan Carlos López-Ramos; Juan Manuel Encinas; Paula Fernández-Vizarra; Susana Castro-Blanco; Alfredo Martínez; Ricardo Martinez Murillo; Pedro Lorenzo; Juan Angel Pedrosa; María Angeles Peinado; José Rodrigo
Postnatal changes in the nitric oxide system of the rat cerebral cortex after hypoxia during delivery.
Brain research. Developmental brain research 2003;142(2):177-92.
2003: Maria Moro; Olivia Hurtado; Antonio Cárdenas; Cristina Romera; José L M Madrigal; Paz Fernández-Tomé; Juan C Leza; Pedro Lorenzo; ignacio lizasoain
Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system.
Neuro-Signals 2003;12(2):53-8.
2002: Antonio Cárdenas; Maria Moro; Juan C Leza; Esther O'Shea; Antoni Dávalos; José Castillo; Pedro Lorenzo; ignacio lizasoain
Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(11):1297-302.
2002: José L M Madrigal; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Juan C Leza
Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide.
Brain research 2002;938(1-2):87-91.
2002: Olivia Hurtado; ignacio lizasoain; Paz Fernández-Tomé; Alberto Alvarez-Barrientos; Juan C Leza; Pedro Lorenzo; Maria Moro
TACE/ADAM17-TNF-alpha pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamate.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(5):576-85.
2002: Javier De Cristóbal; José L M Madrigal; ignacio lizasoain; Pedro Lorenzo; Juan C Leza; Maria Moro
Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats.
Neuroreport 2002;13(2):217-21.
2002: José L M Madrigal; Olivia Hurtado; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Antonio Castrillo; Lisardo Boscá; Juan C Leza
The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(2):155-63.
2002: Javier De Cristóbal; Antonio Cárdenas; ignacio lizasoain; Juan C Leza; Paz Fernández-Tomé; Pedro Lorenzo; Maria Moro
Inhibition of glutamate release via recovery of ATP levels accounts for a neuroprotective effect of aspirin in rat cortical neurons exposed to oxygen-glucose deprivation.
Stroke; a journal of cerebral circulation 2002;33(1):261-7.
2001: Arturo Colón; Luis Menchén; Olivia Hurtado; Javier De Cristóbal; ignacio lizasoain; Juan C Leza; Pedro Lorenzo; Maria Moro
Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis.
Cytokine 2001;16(6):220-6.
2001: Javier De Cristóbal; Maria Moro; Antoni Dávalos; José Castillo; Juan C Leza; Jorge Camarero; M Isabel Colado; Pedro Lorenzo; ignacio lizasoain
Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats.
Journal of neurochemistry 2001;79(2):456-9.
2001: Luis Menchén; Arturo Colón; Maria Moro; Juan C Leza; ignacio lizasoain; Pedro Menchén; E Alvarez; Pedro Lorenzo
N-(3-(aminomethyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats.
Life sciences 2001;69(4):479-91.
2001: Olivia Hurtado; Antonio Cárdenas; ignacio lizasoain; Lisardo Boscá; Juan C Leza; Pedro Lorenzo; Maria Moro
Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices.
Neuropharmacology 2001;40(8):1094-102.
2001: José L M Madrigal; R Olivenza; Maria Moro; ignacio lizasoain; Pedro Lorenzo; J Rodrigo; Juan C Leza
Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(4):420-9.
2001: José L M Madrigal; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Antonio Castrillo; Lisardo Boscá; Juan C Leza
Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms.
Journal of neurochemistry 2001;76(2):532-8.
2000: Antonio Cárdenas; Olivia Hurtado; Juan C Leza; Pedro Lorenzo; R Bartrons; ignacio lizasoain; Maria Moro
Fructose-1,6-bisphosphate inhibits the expression of inducible nitric oxide synthase caused by oxygen-glucose deprivation through the inhibition of glutamate release in rat forebrain slices.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(3):208-12.
2000: Arturo Colón; Luis Menchén; ignacio lizasoain; Juan C Leza; Pedro Menchén; V González-Lara; Maria Moro; Pedro Lorenzo
Inducible nitric oxide synthase activity is expressed not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker.
The American journal of gastroenterology 2000;95(5):1371-3.
2000: Antonio Cárdenas; Maria Moro; Olivia Hurtado; Juan C Leza; Pedro Lorenzo; Antonio Castrillo; OG Bodelón; Lisardo Boscá; ignacio lizasoain
Implication of glutamate in the expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices.
Journal of neurochemistry 2000;74(5):2041-8.
2000: Maria Moro; J De Alba; Antonio Cárdenas; Javier De Cristóbal; Juan C Leza; ignacio lizasoain; María José M Díaz-Guerra; Lisardo Boscá; Pedro Lorenzo
Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices.
Neuropharmacology 2000;39(7):1309-18.
2000: R Olivenza; Maria Moro; ignacio lizasoain; Pedro Lorenzo; Ana Patricia Fernández; J Rodrigo; Lisardo Boscá; Juan C Leza
Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex.
Journal of neurochemistry 2000;74(2):785-91.
2000: B Cuéllar; Ana Patricia Fernández; ignacio lizasoain; Maria Moro; Pedro Lorenzo; María Luisa Bentura; José Rodrigo; Juan C Leza
Up-regulation of neuronal NO synthase immunoreactivity in opiate dependence and withdrawal.
Psychopharmacology 2000;148(1):66-73.
1999: Paz Fernández-Tomé; ignacio lizasoain; Juan C Leza; Pedro Lorenzo; Maria Moro
Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones.
Neuropharmacology 1999;38(9):1307-15.
1999: J De Alba; Antonio Cárdenas; Maria Moro; Juan C Leza; Pedro Lorenzo; ignacio lizasoain
Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion.
General pharmacology 1999;32(5):577-81.
1999: J De Alba; Antonio Cárdenas; Maria Moro; Juan C Leza; Pedro Lorenzo; Lisardo Boscá; ignacio lizasoain
Down-regulation of neuronal nitric oxide synthase by nitric oxide after oxygen-glucose deprivation in rat forebrain slices.
Journal of neurochemistry 1999;72(1):248-54.
1998: L Otto Uttenthal; David Alonso; Ana Patricia Fernández; R O Campbell; Maria Moro; Juan C Leza; ignacio lizasoain; Francisco J Esteban; Juan B Barroso; Raquel Valderrama; Juan Angel Pedrosa; María Angeles Peinado; Julia Serrano; Ana Richart; María Luisa Bentura; María Santacana; Ricardo Martínez-Murillo; José Rodrigo
Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat.
Microscopy research and technique 1998;43(1):75-88.
1998: Juan C Leza; E Salas; Grzegorz Sawicki; J C Russell; M W Radomski
The effects of stress on homeostasis in JCR-LA-cp rats: the role of nitric oxide.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1397-403.
1998: Antonio Cárdenas; J De Alba; Maria Moro; Juan C Leza; Pedro Lorenzo; ignacio lizasoain
Protective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation.
European journal of pharmacology 1998;354(2-3):161-5.
1998: Maria Moro; Paz Fernández-Tomé; Juan C Leza; Pedro Lorenzo; ignacio lizasoain
Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.
Neuropharmacology 1998;37(8):1071-9.
1998: Maria Moro; J De Alba; Juan C Leza; Pedro Lorenzo; Ana Patricia Fernández; María Luisa Bentura; Lisardo Boscá; José Rodrigo; ignacio lizasoain
Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices.
The European journal of neuroscience 1998;10(2):445-56.
1998: Maria Moro; Juan C Leza; Pedro Lorenzo; ignacio lizasoain
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Free radical research 1998;28(2):193-204.
1996: ignacio lizasoain; Juan C Leza; B Cuéllar; Maria Moro; Pedro Lorenzo
Inhibition of morphine withdrawal by lamotrigine: involvement of nitric oxide.
European journal of pharmacology 1996;299(1-3):41-5.
1996: O San-Martin-Clark; B Cuellar; Juan C Leza; ignacio lizasoain; Pedro Lorenzo
Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice.
Psychopharmacology 1996;123(3):297-302.
1996: Juan C Leza; ignacio lizasoain; B Cuéllar; Maria Moro; Pedro Lorenzo
Correlation between brain nitric oxide synthase activity and opiate withdrawal.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(3):349-54.
1995: Juan C Leza; ignacio lizasoain; O San-Martín-Clark; Pedro Lorenzo
Morphine-induced changes in cerebral and cerebellar nitric oxide synthase activity.
European journal of pharmacology 1995;285(1):95-8.
1995: Eduardo Villamor; Francisco Pérez-Vizcaíno; T Ruiz; Juan C Leza; M Moro; Juan Tamargo
Group B Streptococcus and E. coli LPS-induced NO-dependent hyporesponsiveness to noradrenaline in isolated intrapulmonary arteries of neonatal piglets.
British journal of pharmacology 1995;115(2):261-6.
1995: O San-Martín-Clark; B Cuéllar; J De Alba; Juan C Leza; Pedro Lorenzo
Changes induced by sodium cromoglycate in brain catecholamine turnover in morphine dependent and abstinent mice.
Psychopharmacology 1995;118(3):347-53.
1993: Juan C Leza; Pedro Lorenzo
[The central effects of antihistaminic drugs].
Medicina clínica 1993;101(1):24-7.
1993: O San-Martin-Clark; Juan C Leza; ignacio lizasoain; Pedro Lorenzo
Changes induced by sodium cromoglycate on brain serotonin turnover in morphine dependent and abstinent mice.
Psychopharmacology 1993;111(2):233-8.
1992: Juan C Leza; ignacio lizasoain; O S Martín-Clark; Pedro Lorenzo
Role of sodium cromoglycate on analgesia, locomotor activity and opiate withdrawal in mice.
Psychopharmacology 1992;107(4):595-600.
1991: M Navarro; ignacio lizasoain; Juan C Leza; Pedro Lorenzo
An original method for assessment of the jumping test.
Methods and findings in experimental and clinical pharmacology 1991;13(7):443-7.
1991: ignacio lizasoain; Juan C Leza; Pedro Lorenzo
Buprenorphine: bell-shaped dose-response curve for its antagonist effects.
General pharmacology 1991;22(2):297-300.
1991: Miguel Navarro; Juan C Leza; ignacio lizasoain; Pedro Lorenzo
Influence of psychogenetics in opiate tolerance and abstinence in mice.
General pharmacology 1991;22(4):713-6.
1991: Juan C Leza; ignacio lizasoain; Pedro Lorenzo
Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity.
General pharmacology 1991;22(2):293-6.
1990: Juan C Leza; ignacio lizasoain; Pedro Lorenzo
H1- and H2-histamine receptor blockers and opiate analgesia in mice.
Methods and findings in experimental and clinical pharmacology 1990;12(10):671-8.
1990: M I Martin; ignacio lizasoain; Juan C Leza
Calcium channel blockers: effect on morphine-induced hypermotility.
Psychopharmacology 1990;101(2):267-70.
1990: Juan C Leza; ignacio lizasoain; Pedro Lorenzo
Effects of antihistaminics on naloxone-induced withdrawal in morphine-dependent mice.
Psychopharmacology 1990;102(1):106-11.
1988: Pedro Lorenzo; Juan C Leza
[Buprenorphine: pharmacologic and clinical aspects].
Revista clínica española 1988;182(4):230-3.