Yves-Alain Barde

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Pasutto Francesca; Matsumoto Tomoya; Mardin Christian Y; Sticht Heinrich; Brandstätter Johann H; Michels-Rautenstrauss Karin; Weisschuh Nicole; Gramer Eugen; Ramdas Wishal D; van Koolwijk Leonieke M E; Klaver Caroline C W; Vingerling Johannes R; Weber Bernhard H F; Kruse Friedrich E; Rautenstrauss Bernd; Barde Yves-Alain; Reis André
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.
Matsumoto Tomoya; Rauskolb Stefanie; Polack Martin; Klose Johannes; Kolbeck Roland; Korte Martin; Barde Yves-Alain
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.
Nicholson J R; Peter J-C; Lecourt A-C; Barde Y-A; Hofbauer K G
Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function.

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2009: Pasutto Francesca; Matsumoto Tomoya; Mardin Christian Y; Sticht Heinrich; Brandstätter Johann H; Michels-Rautenstrauss Karin; Weisschuh Nicole; Gramer Eugen; Ramdas Wishal D; van Koolwijk Leonieke M E; Klaver Caroline C W; Vingerling Johannes R; Weber Bernhard H F; Kruse Friedrich E; Rautenstrauss Bernd; Barde Yves-Alain; Reis André
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.
American journal of human genetics 2009;85(4):447-56.
2008: Matsumoto Tomoya; Rauskolb Stefanie; Polack Martin; Klose Johannes; Kolbeck Roland; Korte Martin; Barde Yves-Alain
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.
Nature neuroscience 2008;11(2):131-3.
2007: Nicholson J R; Peter J-C; Lecourt A-C; Barde Y-A; Hofbauer K G
Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function.
Journal of neuroendocrinology 2007;19(12):974-82.
2007: Nikoletopoulou Vassiliki; Plachta Nicolas; Allen Nicolas D; Pinto Luisa; Götz Magdalena; Barde Yves-Alain
Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.
Cell stem cell 2007;1(5):529-40.
2007: Plachta Nicolas; Annaheim Christine; Bissière Stephanie; Lin Shuo; Rüegg Markus; Hoving Sjouke; Müller Dieter; Poirier Françoise; Bibel Miriam; Barde Yves-Alain
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
Nature neuroscience 2007;10(6):712-9.
2007: Bibel Miriam; Richter Jens; Lacroix Emmanuel; Barde Yves-Alain
Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells.
Nature protocols 2007;2(5):1034-43.
2005: Zagrebelsky Marta; Holz Andreas; Dechant Georg; Barde Yves-Alain; Bonhoeffer Tobias; Korte Martin
The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(43):9989-99.
2005: Rösch Harald; Schweigreiter Rüdiger; Bonhoeffer Tobias; Barde Yves-Alain; Korte Martin
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7362-7.
2005: Götz Magdalena; Barde Yves-Alain
Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons.
Neuron 2005;46(3):369-72.
2004: Plachta Nicolas; Bibel Miriam; Tucker Kerry Lee; Barde Yves-Alain
Developmental potential of defined neural progenitors derived from mouse embryonic stem cells.
Development (Cambridge, England) 2004;131(21):5449-56.
2004: Bibel Miriam; Richter Jens; Schrenk Katrin; Tucker Kerry Lee; Staiger Volker; Korte Martin; Goetz Magdalena; Barde Yves-Alain
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Nature neuroscience 2004;7(9):1003-9.
2004: Barde Y-A
Death of injured neurons caused by the precursor of nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):5703-4.
2003: Andorfer Cathy; Kress Yvonne; Espinoza Marisol; de Silva Rohan; Tucker Kerry L; Barde Yves-Alain; Duff Karen; Davies Peter
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.
Journal of neurochemistry 2003;86(3):582-90.
2002: Dechant Georg; Barde Yves-Alain
The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system.
Nature neuroscience 2002;5(11):1131-6.
2002: Barde Yves-Alain
Neurobiology: neurotrophin channels excitement.
Nature 2002;419(6908):683-4.
2002: Wernig Marius; Tucker Kerry Lee; Gornik Volker; Schneiders Angelika; Buschwald Rachel; Wiestler Otmar D; Barde Yves-Alain; Brüstle Oliver
Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation.
Journal of neuroscience research 2002;69(6):918-24.
2002: Naumann Thomas; Casademunt Elisabeth; Hollerbach Ewald; Hofmann Jutta; Dechant Georg; Frotscher Michael; Barde Yves-Alain
Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2409-18.
2002: Heins Nico; Malatesta Paolo; Cecconi Francesco; Nakafuku Masato; Tucker Kerry Lee; Hack Michael A; Chapouton Prisca; Barde Yves-Alain; Götz Magdalena
Glial cells generate neurons: the role of the transcription factor Pax6.
Nature neuroscience 2002;5(4):308-15.
2002: Neumann Harald; Schweigreiter Rudiger; Yamashita Toshihide; Rosenkranz Katja; Wekerle Hartmut; Barde Yves-Alain
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(3):854-62.
2001: Benzel I; Barde Y A; Casademunt E
Strain-specific complementation between NRIF1 and NRIF2, two zinc finger proteins sharing structural and biochemical properties.
Gene 2001;281(1-2):19-30.
2001: Friedel R H; Stubbusch J; Barde Y A; Schnürch H
A novel 7-transmembrane receptor expressed in nerve growth factor-dependent sensory neurons.
Molecular and cellular neurosciences 2001;17(1):31-40.
2001: Tucker K L; Meyer M; Barde Y A
Neurotrophins are required for nerve growth during development.
Nature neuroscience 2001;4(1):29-37.
2000: Bibel M; Barde Y A
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.
Genes & development 2000;14(23):2919-37.
2000: Sommerfeld M T; Schweigreiter R; Barde Y A; Hoppe E
Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB.
The Journal of biological chemistry 2000;275(12):8982-90.
1999: Yamashita T; Tucker K L; Barde Y A
Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth.
Neuron 1999;24(3):585-93.
1999: Casademunt E; Carter B D; Benzel I; Frade J M; Dechant G; Barde Y A
The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death.
The EMBO journal 1999;18(21):6050-61.
1999: Chen G; Kolbeck R; Barde Y A; Bonhoeffer T; Kossel A
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):7983-90.
1999: Kolbeck R; Bartke I; Eberle W; Barde Y A
Brain-derived neurotrophic factor levels in the nervous system of wild-type and neurotrophin gene mutant mice.
Journal of neurochemistry 1999;72(5):1930-8.
1999: Bibel M; Hoppe E; Barde Y A
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR.
The EMBO journal 1999;18(3):616-22.
1999: Frade J M; Barde Y A
Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.
Development (Cambridge, England) 1999;126(4):683-90.
1998: Frade J M; Barde Y A
Nerve growth factor: two receptors, multiple functions.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(2):137-45.
1998: Frade J M; Barde Y A
Microglia-derived nerve growth factor causes cell death in the developing retina.
Neuron 1998;20(1):35-41.
1997: Friedel R H; Schnürch H; Stubbusch J; Barde Y A
Identification of genes differentially expressed by nerve growth factor- and neurotrophin-3-dependent sensory neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12670-5.
1997: Dechant G; Tsoulfas P; Parada L F; Barde Y A
The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5281-7.
1997: Dechant G; Barde Y A
Signalling through the neurotrophin receptor p75NTR.
Current opinion in neurobiology 1997;7(3):413-8.
1997: Cellerino A; Carroll P; Thoenen H; Barde Y A
Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor.
Molecular and cellular neurosciences 1997;9(5-6):397-408.
1996: Frade J M; Rodríguez-Tébar A; Barde Y A
Induction of cell death by endogenous nerve growth factor through its p75 receptor.
Nature 1996;383(6596):166-8.
1996: Bovolenta P; Frade J M; Martí E; Rodríguez-Peña M A; Barde Y A; Rodríguez-Tébar A
Neurotrophin-3 antibodies disrupt the normal development of the chick retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(14):4402-10.
1996: Strohmaier C; Carter B D; Urfer R; Barde Y A; Dechant G
A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor.
The EMBO journal 1996;15(13):3332-7.
1996: Carter B D; Kaltschmidt C; Kaltschmidt B; Offenhäuser N; Böhm-Matthaei R; Baeuerle P A; Barde Y A
Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.
Science (New York, N.Y.) 1996;272(5261):542-5.
1996: Ockel M; von Schack D; Schröpel A; Dechant G; Lewin G R; Barde Y A
Roles of neurotrophin-3 during early development of the peripheral nervous system.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1338):383-7.
1996: Ockel M; Lewin G R; Barde Y A
In vivo effects of neurotrophin-3 during sensory neurogenesis.
Development (Cambridge, England) 1996;122(1):301-7.
1996: Carter B D; Dechant G; Frade J M; Kaltschmidt C; Barde Y A
Neurotrophins and their p75 receptor.
Cold Spring Harbor symposia on quantitative biology 1996;61():407-15.
1996: Lewin G R; Barde Y A
Physiology of the neurotrophins.
Annual review of neuroscience 1996;19():289-317.
1995: Schröpel A; von Schack D; Dechant G; Barde Y A
Early expression of the nerve growth factor receptor ctrkA in chick sympathetic and sensory ganglia.
Molecular and cellular neurosciences 1995;6(6):544-66.
1995: Carter B D; Zirrgiebel U; Barde Y A
Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor.
The Journal of biological chemistry 1995;270(37):21751-7.
1995: Brill G; Kahane N; Carmeli C; von Schack D; Barde Y A; Kalcheim C
Epithelial-mesenchymal conversion of dermatome progenitors requires neural tube-derived signals: characterization of the role of Neurotrophin-3.
Development (Cambridge, England) 1995;121(8):2583-94.
1995: Biffo S; Offenhäuser N; Carter B D; Barde Y A
Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development.
Development (Cambridge, England) 1995;121(8):2461-70.
1994: Kolbeck R; Jungbluth S; Barde Y A
Characterisation of neurotrophin dimers and monomers.
European journal of biochemistry / FEBS 1994;225(3):995-1003.
1994: Barde Y A
Neurotrophic factors: an evolutionary perspective.
Journal of neurobiology 1994;25(11):1329-33.
1994: Herzog K H; Bailey K; Barde Y A
Expression of the BDNF gene in the developing visual system of the chick.
Development (Cambridge, England) 1994;120(6):1643-9.
1994: Gaese F; Kolbeck R; Barde Y A
Sensory ganglia require neurotrophin-3 early in development.
Development (Cambridge, England) 1994;120(6):1613-9.
1994: Jungbluth S; Bailey K; Barde Y A
Purification and characterisation of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer.
European journal of biochemistry / FEBS 1994;221(2):677-85.
1994: Dechant G; Rodríguez-Tébar A; Barde Y A
Neurotrophin receptors.
Progress in neurobiology 1994;42(2):347-52.
1994: Barres B A; Raff M C; Gaese F; Bartke I; Dechant G; Barde Y A
A crucial role for neurotrophin-3 in oligodendrocyte development.
Nature 1994;367(6461):371-5.
1994: Schnell L; Schneider R; Kolbeck R; Barde Y A; Schwab M E
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion.
Nature 1994;367(6459):170-3.
1994: Biffo S; Dechant G; Okazawa H; Barde Y A
Molecular control of neuronal survival in the chick embryo.
EXS 1994;71():39-48.
1994: Barde Y A
Neurotrophins: a family of proteins supporting the survival of neurons.
Progress in clinical and biological research 1994;390():45-56.
1993: Dechant G; Biffo S; Okazawa H; Kolbeck R; Pottgiesser J; Barde Y A
Expression and binding characteristics of the BDNF receptor chick trkB.
Development (Cambridge, England) 1993;119(2):545-58.
1993: Dechant G; Rodríguez-Tébar A; Kolbeck R; Barde Y A
Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2610-6.
1992: Sendtner M; Holtmann B; Kolbeck R; Thoenen H; Barde Y A
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section.
Nature 1992;360(6406):757-9.
1992: Rodríguez-Tébar A; Dechant G; Götz R; Barde Y A
Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.
The EMBO journal 1992;11(3):917-22.
1992: Götz R; Kolbeck R; Lottspeich F; Barde Y A
Production and characterization of recombinant mouse neurotrophin-3.
European journal of biochemistry / FEBS 1992;204(2):745-9.
1991: Rodríguez-Tébar A; Dechant G; Barde Y A
Neurotrophins: structural relatedness and receptor interactions.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1991;331(1261):255-8.
1990: Hofer M; Pagliusi S R; Hohn A; Leibrock J; Barde Y A
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.
The EMBO journal 1990;9(8):2459-64.
1990: Rodriguez-Tébar A; Dechant G; Barde Y A
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor.
Neuron 1990;4(4):487-92.
1990: Hohn A; Leibrock J; Bailey K; Barde Y A
Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family.
Nature 1990;344(6264):339-41.
1990: Barde Y A
The nerve growth factor family.
Progress in growth factor research 1990;2(4):237-48.
1989: Rodriguez-Tébar A; Jeffrey P L; Thoenen H; Barde Y A
The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age.
Developmental biology 1989;136(2):296-303.
1989: Leibrock J; Lottspeich F; Hohn A; Hofer M; Hengerer B; Masiakowski P; Thoenen H; Barde Y A
Molecular cloning and expression of brain-derived neurotrophic factor.
Nature 1989;341(6238):149-52.
1989: Barde Y A
Trophic factors and neuronal survival.
Neuron 1989;2(6):1525-34.
1988: Rodriguez-Tébar A; Barde Y A
Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(9):3337-42.
1987: Kalcheim C; Barde Y A; Thoenen H; Le Douarin N M
In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells.
The EMBO journal 1987;6(10):2871-3.

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Yves-Alain Barde

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