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Yves-Alain Barde

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TOP 3
Martijn P J Dekkers; Yves-Alain Barde
Developmental biology. Programmed cell death in neuronal development.
Vincent Bischoff; Ruben Deogracias; Françoise Poirier; Yves-Alain Barde
Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin Galectin-1.
Morteza Yazdani; Adrian Bird; Ruben Deogracias; Jacky Guy; Raymond A Poot; Yves-Alain Barde
Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.

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All Publications

2013: Martijn P J Dekkers; Yves-Alain Barde
Developmental biology. Programmed cell death in neuronal development.
Science (New York, N.Y.) 2013;340(6128):39-41.
2012: Vincent Bischoff; Ruben Deogracias; Françoise Poirier; Yves-Alain Barde
Seizure-induced neuronal death is suppressed in the absence of the endogenous lectin Galectin-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(44):15590-600.
2012: Morteza Yazdani; Adrian Bird; Ruben Deogracias; Jacky Guy; Raymond A Poot; Yves-Alain Barde
Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.
Stem cells (Dayton, Ohio) 2012;30(10):2128-39.
2012: Ruben Deogracias; Jacky Guy; Mihai Constantin S Ionescu; Kaspar E Vogt; Morteza Yazdani; Martijn P J Dekkers; Yves-Alain Barde
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(35):14230-5.
2012: Vijay K Tiwari; Christiane Wirbelauer; Remi Terranova; Sudhir Thakurela; Yves-Alain Barde; Fritz Boege; Lukas Burger; Ruben Deogracias; Leslie Hoerner; Johannes Kaut; Christian Mielke; Rabih Murr; Vassiliki Nikoletopoulou; Antoine H F M Peters; Dirk Schübeler
Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(16):E934-43.
2012: Sandra Dieni; Michael Frotscher; Eckart D Gundelfinger; Mihai S Ionescu; Masami Kojima; Tomoya Matsumoto; Sigrun Nestel; Stefanie Rauskolb; Martijn Dekkers; Ruben Deogracias; Yves-Alain Barde
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons.
The Journal of cell biology 2012;196(6):775-88.
2011: Vincent Bischoff; Vassiliki Nikoletopoulou; Yves-Alain Barde
[Save or kill - the ambivalence of neurotrophin receptors].
Médecine sciences : M/S 2011;27(2):119-21.
2010: Vassiliki Nikoletopoulou; Heiko Lickert; José Maria Frade; Chantal Rencurel; Patrizia Giallonardo; Lixin Zhang; Miriam Bibel; Yves-Alain Barde
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.
Nature 2010;467(7311):59-63.
2010: Stefanie Rauskolb; Marta Zagrebelsky; Anita Dreznjak; Ruben Deogracias; Tomoya Matsumoto; Stefan Wiese; Beat Erne; Michael Sendtner; Nicole Schaeren-Wiemers; Martin Korte; Yves-Alain Barde
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(5):1739-49.
2009: Francesca Pasutto; Tomoya Matsumoto; Christian Y Mardin; Heinrich Sticht; Johann H Brandstätter; Karin Michels-Rautenstrauss; Nicole Weisschuh; Eugen Gramer; Wishal D Ramdas; Leonieke M E van Koolwijk; Caroline C W Klaver; Johannes R Vingerling; Bernhard H F Weber; Friedrich E Kruse; Bernd Rautenstrauss; Yves-Alain Barde; André Reis
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.
American journal of human genetics 2009;85(4):447-56.
2008: Tomoya Matsumoto; Stefanie Rauskolb; Martin Polack; Johannes Klose; Roland W Kolbeck; Martin Korte; Yves-Alain Barde
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.
Nature neuroscience 2008;11(2):131-3.
2007: Janet R Nicholson; J-C Peter; A-C Lecourt; Yves-Alain Barde; Karl G Hofbauer
Melanocortin-4 receptor activation stimulates hypothalamic brain-derived neurotrophic factor release to regulate food intake, body temperature and cardiovascular function.
Journal of neuroendocrinology 2007;19(12):974-82.
2007: Vassiliki Nikoletopoulou; Nicolas Plachta; Nicolas D Allen; Luisa Pinto; Magdalena Götz; Yves-Alain Barde
Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.
Cell stem cell 2007;1(5):529-40.
2007: Nicolas Plachta; Christine Annaheim; Stephanie Bissière; Shuo Lin; Markus Rüegg; Sjouke Hoving; Dieter Müller; Françoise Poirier; Miriam Bibel; Yves-Alain Barde
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells.
Nature neuroscience 2007;10(6):712-9.
2007: Miriam Bibel; Jens Richter; Emmanuel Lacroix; Yves-Alain Barde
Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells.
Nature protocols 2007;2(5):1034-43.
2005: Marta Zagrebelsky; Andreas Holz; Georg Dechant; Yves-Alain Barde; Tobias Bonhoeffer; Martin Korte
The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(43):9989-99.
2005: Harald Rösch; Rüdiger Schweigreiter; Tobias Bonhoeffer; Yves-Alain Barde; Martin Korte
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7362-7.
2005: Magdalena Götz; Yves-Alain Barde
Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons.
Neuron 2005;46(3):369-72.
2004: Nicolas Plachta; Miriam Bibel; Kerry Lee Tucker; Yves-Alain Barde
Developmental potential of defined neural progenitors derived from mouse embryonic stem cells.
Development (Cambridge, England) 2004;131(21):5449-56.
2004: Miriam Bibel; Jens Richter; Katrin Schrenk; Kerry Lee Tucker; Volker Staiger; Martin Korte; Magdalena Goetz; Yves-Alain Barde
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Nature neuroscience 2004;7(9):1003-9.
2004: Yves-Alain Barde
Death of injured neurons caused by the precursor of nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):5703-4.
2003: Cathy Andorfer; Yvonne Kress; Marisol Espinoza; Rohan de Silva; Kerry L Tucker; Yves-Alain Barde; karen duff; Peter Davies
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.
Journal of neurochemistry 2003;86(3):582-90.
2002: Georg Dechant; Yves-Alain Barde
The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system.
Nature neuroscience 2002;5(11):1131-6.
2002: Yves-Alain Barde
Neurobiology: neurotrophin channels excitement.
Nature 2002;419(6908):683-4.
2002: Marius Wernig; Kerry Lee Tucker; Volker Gornik; Angelika Schneiders; Rachel Buschwald; Otmar D Wiestler; Yves-Alain Barde; Oliver Brüstle
Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation.
Journal of neuroscience research 2002;69(6):918-24.
2002: Thomas Naumann; Elisabeth Casademunt; Ewald Hollerbach; Jutta Hofmann; Georg Dechant; Michael Frotscher; Yves-Alain Barde
Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2409-18.
2002: Nico Heins; Paolo Malatesta; Francesco Cecconi; Masato Nakafuku; Kerry Lee Tucker; Michael A Hack; Prisca Chapouton; Yves-Alain Barde; Magdalena Götz
Glial cells generate neurons: the role of the transcription factor Pax6.
Nature neuroscience 2002;5(4):308-15.
2002: Harald Neumann; Rüdiger Schweigreiter; Toshihide Yamashita; Katja Rosenkranz; Hartmut Wekerle; Yves-Alain Barde
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(3):854-62.
2001: I Benzel; Yves-Alain Barde; Elisabeth Casademunt
Strain-specific complementation between NRIF1 and NRIF2, two zinc finger proteins sharing structural and biochemical properties.
Gene 2001;281(1-2):19-30.
2001: R H Friedel; J Stubbusch; Yves-Alain Barde; H Schnürch
A novel 7-transmembrane receptor expressed in nerve growth factor-dependent sensory neurons.
Molecular and cellular neurosciences 2001;17(1):31-40.
2001: K L Tucker; M Meyer; Yves-Alain Barde
Neurotrophins are required for nerve growth during development.
Nature neuroscience 2001;4(1):29-37.
2000: Miriam Bibel; Yves-Alain Barde
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.
Genes & development 2000;14(23):2919-37.
2000: M T Sommerfeld; Rüdiger Schweigreiter; Yves-Alain Barde; E Hoppe
Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB.
The Journal of biological chemistry 2000;275(12):8982-90.
1999: T Yamashita; K L Tucker; Yves-Alain Barde
Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth.
Neuron 1999;24(3):585-93.
1999: Elisabeth Casademunt; B D Carter; I Benzel; JM Frade; Georg Dechant; Yves-Alain Barde
The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death.
The EMBO journal 1999;18(21):6050-61.
1999: G Chen; Roland W Kolbeck; Yves-Alain Barde; Tobias Bonhoeffer; Albrecht Kossel
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(18):7983-90.
1999: Roland W Kolbeck; I Bartke; W Eberle; Yves-Alain Barde
Brain-derived neurotrophic factor levels in the nervous system of wild-type and neurotrophin gene mutant mice.
Journal of neurochemistry 1999;72(5):1930-8.
1999: Miriam Bibel; E Hoppe; Yves-Alain Barde
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR.
The EMBO journal 1999;18(3):616-22.
1999: JM Frade; Yves-Alain Barde
Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.
Development (Cambridge, England) 1999;126(4):683-90.
1998: JM Frade; Yves-Alain Barde
Nerve growth factor: two receptors, multiple functions.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(2):137-45.
1998: JM Frade; Yves-Alain Barde
Microglia-derived nerve growth factor causes cell death in the developing retina.
Neuron 1998;20(1):35-41.
1997: R H Friedel; H Schnürch; J Stubbusch; Yves-Alain Barde
Identification of genes differentially expressed by nerve growth factor- and neurotrophin-3-dependent sensory neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12670-5.
1997: Georg Dechant; Pantelis Tsoulfas; Luis F Parada; Yves-Alain Barde
The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5281-7.
1997: Georg Dechant; Yves-Alain Barde
Signalling through the neurotrophin receptor p75NTR.
Current opinion in neurobiology 1997;7(3):413-8.
1997: Alessandro Cellerino; P Carroll; Hans Thoenen; Yves-Alain Barde
Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor.
Molecular and cellular neurosciences 1997;9(5-6):397-408.
1996: JM Frade; Alfredo Rodríguez-Tébar; Yves-Alain Barde
Induction of cell death by endogenous nerve growth factor through its p75 receptor.
Nature 1996;383(6596):166-8.
1996: Paola Bovolenta; JM Frade; E Martí; M A Rodríguez-Peña; Yves-Alain Barde; Alfredo Rodríguez-Tébar
Neurotrophin-3 antibodies disrupt the normal development of the chick retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(14):4402-10.
1996: C Strohmaier; B D Carter; R Urfer; Yves-Alain Barde; Georg Dechant
A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor.
The EMBO journal 1996;15(13):3332-7.
1996: B D Carter; Christian Kaltschmidt; barbara kaltschmidt; N Offenhäuser; R Böhm-Matthaei; P A Baeuerle; Yves-Alain Barde
Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.
Science (New York, N.Y.) 1996;272(5261):542-5.
1996: M Ockel; D von Schack; A Schröpel; Georg Dechant; G R Lewin; Yves-Alain Barde
Roles of neurotrophin-3 during early development of the peripheral nervous system.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1338):383-7.
1996: B D Carter; Georg Dechant; JM Frade; Christian Kaltschmidt; Yves-Alain Barde
Neurotrophins and their p75 receptor.
Cold Spring Harbor symposia on quantitative biology 1996;61():407-15.
1996: G R Lewin; Yves-Alain Barde
Physiology of the neurotrophins.
Annual review of neuroscience 1996;19():289-317.
1996: M Ockel; G R Lewin; Yves-Alain Barde
In vivo effects of neurotrophin-3 during sensory neurogenesis.
Development (Cambridge, England) 1996;122(1):301-7.
1995: A Schröpel; D von Schack; Georg Dechant; Yves-Alain Barde
Early expression of the nerve growth factor receptor ctrkA in chick sympathetic and sensory ganglia.
Molecular and cellular neurosciences 1995;6(6):544-66.
1995: B D Carter; U Zirrgiebel; Yves-Alain Barde
Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor.
The Journal of biological chemistry 1995;270(37):21751-7.
1995: G Brill; Nitza Kahane; C Carmeli; D von Schack; Yves-Alain Barde; Chaya Kalcheim
Epithelial-mesenchymal conversion of dermatome progenitors requires neural tube-derived signals: characterization of the role of Neurotrophin-3.
Development (Cambridge, England) 1995;121(8):2583-94.
1995: S Biffo; N Offenhäuser; B D Carter; Yves-Alain Barde
Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development.
Development (Cambridge, England) 1995;121(8):2461-70.
1994: Roland W Kolbeck; S Jungbluth; Yves-Alain Barde
Characterisation of neurotrophin dimers and monomers.
European journal of biochemistry / FEBS 1994;225(3):995-1003.
1994: Yves-Alain Barde
Neurotrophic factors: an evolutionary perspective.
Journal of neurobiology 1994;25(11):1329-33.
1994: K H Herzog; K Bailey; Yves-Alain Barde
Expression of the BDNF gene in the developing visual system of the chick.
Development (Cambridge, England) 1994;120(6):1643-9.
1994: F Gaese; Roland W Kolbeck; Yves-Alain Barde
Sensory ganglia require neurotrophin-3 early in development.
Development (Cambridge, England) 1994;120(6):1613-9.
1994: S Jungbluth; K Bailey; Yves-Alain Barde
Purification and characterisation of a brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) heterodimer.
European journal of biochemistry / FEBS 1994;221(2):677-85.
1994: Georg Dechant; Alfredo Rodríguez-Tébar; Yves-Alain Barde
Neurotrophin receptors.
Progress in neurobiology 1994;42(2):347-52.
1994: Ben A Barres; Martin Raff; F Gaese; I Bartke; Georg Dechant; Yves-Alain Barde
A crucial role for neurotrophin-3 in oligodendrocyte development.
Nature 1994;367(6461):371-5.
1994: Lisa Schnell; R Schneider; Roland W Kolbeck; Yves-Alain Barde; Martin E Schwab
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion.
Nature 1994;367(6459):170-3.
1994: S Biffo; Georg Dechant; hitoshi okazawa; Yves-Alain Barde
Molecular control of neuronal survival in the chick embryo.
EXS 1994;71():39-48.
1994: Yves-Alain Barde
Neurotrophins: a family of proteins supporting the survival of neurons.
Progress in clinical and biological research 1994;390():45-56.
1993: Georg Dechant; S Biffo; hitoshi okazawa; Roland W Kolbeck; J Pottgiesser; Yves-Alain Barde
Expression and binding characteristics of the BDNF receptor chick trkB.
Development (Cambridge, England) 1993;119(2):545-58.
1993: Georg Dechant; Alfredo Rodríguez-Tébar; Roland W Kolbeck; Yves-Alain Barde
Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2610-6.
1992: Michael Sendtner; Bettina Holtmann; Roland W Kolbeck; H Thoenen; Yves-Alain Barde
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section.
Nature 1992;360(6406):757-9.
1992: Alfredo Rodríguez-Tébar; Georg Dechant; R Götz; Yves-Alain Barde
Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.
The EMBO journal 1992;11(3):917-22.
1992: R Götz; Roland W Kolbeck; F Lottspeich; Yves-Alain Barde
Production and characterization of recombinant mouse neurotrophin-3.
European journal of biochemistry / FEBS 1992;204(2):745-9.
1991: Alfredo Rodríguez-Tébar; Georg Dechant; Yves-Alain Barde
Neurotrophins: structural relatedness and receptor interactions.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1991;331(1261):255-8.
1990: M Hofer; sonia pagliusi; A Hohn; J Leibrock; Yves-Alain Barde
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.
The EMBO journal 1990;9(8):2459-64.
1990: A Rodriguez-Tébar; Georg Dechant; Yves-Alain Barde
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor.
Neuron 1990;4(4):487-92.
1990: A Hohn; J Leibrock; K Bailey; Yves-Alain Barde
Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family.
Nature 1990;344(6264):339-41.
1990: Yves-Alain Barde
The nerve growth factor family.
Progress in growth factor research 1990;2(4):237-48.
1989: A Rodriguez-Tébar; P L Jeffrey; H Thoenen; Yves-Alain Barde
The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age.
Developmental biology 1989;136(2):296-303.
1989: J Leibrock; F Lottspeich; A Hohn; M Hofer; B Hengerer; P Masiakowski; H Thoenen; Yves-Alain Barde
Molecular cloning and expression of brain-derived neurotrophic factor.
Nature 1989;341(6238):149-52.
1989: Yves-Alain Barde
Trophic factors and neuronal survival.
Neuron 1989;2(6):1525-34.
1988: A Rodriguez-Tébar; Yves-Alain Barde
Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(9):3337-42.
1987: Chaya Kalcheim; Yves-Alain Barde; H Thoenen; Nicole M Le Douarin
In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells.
The EMBO journal 1987;6(10):2871-3.