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J Li

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Chunbin Zou; Rebecca M Smith; Courtney Snavely; Yutong Zhao; Bill B Chen; Yan Chen; Tiffany A Coon; J Li; Rama K Mallampalli
SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation.
Sang-Min Lee; J Li; Joseph N McLaughlin; Tim D Oury; Linda L Pearce; Octavia M Peck Palmer; Jim Peterson; Bruce R Pitt; Donna Beer Stolz; Kalidasan Thambiayya; Karla J Wasserloos; Lin Zhu; John F Alcorn; Derek C Angus; Cheryl L Fattman; Daniel R Frederick; Iris Kaminski; Joseph D Latoche; A Murat Kaynar
Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.
Bo He; J Li; Juan Li; Peihui Lin; Jianjie Ma; Christina Mayer; Chunping Qiao; Ru-hang Tang; Noah Weisleder; Bin Xiao; Zhenhua Yuan; Hua Zhu; Chuanxi Cai; Xiao Xiao
Enhancing muscle membrane repair by gene delivery of MG53 ameliorates muscular dystrophy and heart failure in δ-Sarcoglycan-deficient hamsters.

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2013: Chunbin Zou; Rebecca M Smith; Courtney Snavely; Yutong Zhao; Bill B Chen; Yan Chen; Tiffany A Coon; J Li; Rama K Mallampalli
SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation.
The Journal of biological chemistry 2013;288(9):6306-16.
2013: Sang-Min Lee; J Li; Joseph N McLaughlin; Tim D Oury; Linda L Pearce; Octavia M Peck Palmer; Jim Peterson; Bruce R Pitt; Donna Beer Stolz; Kalidasan Thambiayya; Karla J Wasserloos; Lin Zhu; John F Alcorn; Derek C Angus; Cheryl L Fattman; Daniel R Frederick; Iris Kaminski; Joseph D Latoche; A Murat Kaynar
Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2013;304(5):L350-60.
2012: Bo He; J Li; Juan Li; Peihui Lin; Jianjie Ma; Christina Mayer; Chunping Qiao; Ru-hang Tang; Noah Weisleder; Bin Xiao; Zhenhua Yuan; Hua Zhu; Chuanxi Cai; Xiao Xiao
Enhancing muscle membrane repair by gene delivery of MG53 ameliorates muscular dystrophy and heart failure in δ-Sarcoglycan-deficient hamsters.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(4):727-35.
2012: Yang Yang; J Li; Feng Liu; Leaf Huang
Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(3):609-15.
2012: Joe N Kornegay; C Aaron Larsen; J Li; Peter Nghiem; Scott J Schatzberg; Martin A Styner; Sandra Tou; Jiahui Wang; Xiao Xiao; Ratna K Bhavaraju-Sanka; Daniel J Bogan; Janet R Bogan; Martin K Childers; David A Detwiler; Zheng Fan; Kevin M Flanigan; Robert W Grange; James F Howard; Bruce P Keene; Eric Hoffman
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies.
Mammalian genome : official journal of the International Mammalian Genome Society 2012;23(1-2):85-108.
2011: Charles Sfeir; Donghyun Lee; J Li; Xiaoyuan Zhang; Adele L Boskey; Prashant N Kumta
Expression of phosphophoryn is sufficient for the induction of matrix mineralization by mammalian cells.
The Journal of biological chemistry 2011;286(23):20228-38.
2011: Meredith S Shiels; Ruth M Pfeiffer; Mitchell H Gail; H Irene Hall; J Li; Anil K Chaturvedi; Kishor Bhatia; Thomas Uldrick; Robert Yarchoan; James J Goedert; Eric A Engels
Cancer burden in the HIV-infected population in the United States.
Journal of the National Cancer Institute 2011;103(9):753-62.
2011: Zhenhua Yuan; Chunping Qiao; Peiqi Hu; J Li; Xiao Xiao
A versatile adeno-associated virus vector producer cell line method for scalable vector production of different serotypes.
Human gene therapy 2011;22(5):613-24.
2011: Meredith S Shiels; Ruth M Pfeiffer; H Irene Hall; J Li; James J Goedert; Lindsay M Morton; Patricia Hartge; Eric A Engels
Proportions of Kaposi sarcoma, selected non-Hodgkin lymphomas, and cervical cancer in the United States occurring in persons with AIDS, 1980-2007.
JAMA : the journal of the American Medical Association 2011;305(14):1450-9.
2011: Chunping Qiao; Z Yuan; J Li; B He; H Zheng; C Mayer; J Li; Xiao Xiao
Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver.
Gene therapy 2011;18(4):403-10.
2011: Bo Wu; Bin Xiao; Caryn Cloer; Mona Shaban; Arpana Sali; Peijuan Lu; J Li; Kanneboyina Nagaraju; Xiao Xiao; Qi-Long Lu
One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):576-83.
2011: Anh T Nguyen; Bin Xiao; Ronald L Neppl; Eric M Kallin; J Li; Taiping Chen; Da-Zhi Wang; Xiao Xiao; Yi Zhang
DOT1L regulates dystrophin expression and is critical for cardiac function.
Genes & development 2011;25(3):263-74.
2011: Aftab A Ansari; Keith A Reimann; Ann Mayne; Yoshiaki Takahashi; Susan T Stephenson; Rijian Wang; Xinyue Wang; J Li; Andrew A Price; Dawn M Little; Mohammad Zaidi; Robert Lyles; Francios VILLINGER
Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(2):1044-59.
2011: Chunping Qiao; Xiao Xiao; Taeyoung Koo; J Li; J George Dickson
Gene therapy in skeletal muscle mediated by adeno-associated virus vectors.
Methods in molecular biology (Clifton, N.J.) 2011;807():119-40.
2011: Chi-Hsien Wang; Yiumo Michael Chan; Ru-Hang Tang; Bin Xiao; Peijuan Lu; Elizabeth Keramaris-Vrantsis; Hui Zheng; Chunping Qiao; Jiangang Jiang; J Li; Hsin-I Ma; Qilong Lu; Xiao Xiao
Post-Natal knockdown of fukutin-related protein expression in muscle by long-termRNA interference induces dystrophic pathology [corrected].
The American journal of pathology 2011;178(1):261-72.
2011: Lin Yang; J Li; Xiao Xiao
Directed evolution of adeno-associated virus (AAV) as vector for muscle gene therapy.
Methods in molecular biology (Clifton, N.J.) 2011;709():127-39.
2010: J Li; Yin Li; Molly Ogle; Xin Zhou; Minke Song; Shan Ping Yu; Ling WEI
DL-3-n-butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway.
Brain research 2010;1359():216-26.
2010: Chunping Qiao; Wei Zhang; Zhenhua Yuan; Jin-Hong Shin; J Li; Giridhara R Jayandharan; Li Zhong; Arun Srivastava; Xiao Xiao; Dongsheng Duan
Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle.
Human gene therapy 2010;21(10):1343-8.
2010: Jian-Fu Chen; Yazhong Tao; J Li; Zhongliang Deng; Zhen Yan; Xiao Xiao; Da-Zhi Wang
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7.
The Journal of cell biology 2010;190(5):867-79.
2010: Joe N Kornegay; J Li; Janet R Bogan; Daniel J Bogan; Chunlian Chen; Hui Zheng; Bing Wang; Chunping Qiao; James F Howard; Xiao Xiao
Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(8):1501-8.
2010: Liqiao Zhou; Tong Zhu; Xiaojing Ye; Lin Yang; Bing Wang; Xiaoyan Liang; Lina Lu; Yeou-Ping Tsao; Show-Li Chen; J Li; Xiao Xiao
Long-term protection against human papillomavirus e7-positive tumor by a single vaccination of adeno-associated virus vectors encoding a fusion protein of inactivated e7 of human papillomavirus 16/18 and heat shock protein 70.
Human gene therapy 2010;21(1):109-19.
2009: B M Koppanati; J Li; Xiao Xiao; Paula R Clemens
Systemic delivery of AAV8 in utero results in gene expression in diaphragm and limb muscle: treatment implications for muscle disorders.
Gene therapy 2009;16(9):1130-7.
2009: C-Y Yu; Z Yuan; Z Cao; B Wang; Chunping Qiao; J Li; Xiao Xiao
A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery.
Gene therapy 2009;16(8):953-62.
2009: Bing Wang; J Li; Freddie H Fu; Xiao Xiao
Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2009;27(4):421-6.
2009: Lin Yang; Jiangang Jiang; Lauren M Drouin; Mavis Agbandje-McKenna; Chunlian Chen; Chunping Qiao; Dongqiuye Pu; Xiaoyun Hu; Dazhi Wang; J Li; Xiao Xiao
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3946-51.
2009: Alexandre Méjat; Valérie Decostre; J Li; Laure Renou; Akanchha Kesari; Daniel Hantaï; Colin L Stewart; Xiao Xiao; Eric Hoffman; Gisèle Bonne; Tom Misteli
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy.
The Journal of cell biology 2009;184(1):31-44.
2009: Chunping Qiao; J Li; Hui Zheng; Janet Bogan; Jianbin Li; Zhenhua Yuan; Cheng Zhang; Dan Bogan; Joe Kornegay; Xiao Xiao
Hydrodynamic limb vein injection of adeno-associated virus serotype 8 vector carrying canine myostatin propeptide gene into normal dogs enhances muscle growth.
Human gene therapy 2009;20(1):1-10.
2008: Bing Wang; J Li; Freddie H Fu; Chunlian Chen; Xinmei Zhu; Liqiao Zhou; X Jiang; Xiao Xiao
Construction and analysis of compact muscle-specific promoters for AAV vectors.
Gene therapy 2008;15(22):1489-99.
2008: Bo Wu; Hong M Moulton; Patrick L Iversen; Jiangang Jiang; J Li; Jianbin Li; Christopher F Spurney; Arpana Sali; Alfredo D Guerron; Kanneboyina Nagaraju; Timothy Doran; Peijuan Lu; Xiao Xiao; Qi-Long Lu
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):14814-9.
2008: J Li; Wunchang Sun; Bing Wang; Xiao Xiao; Xiang-Qin Liu
Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy.
Human gene therapy 2008;19(9):958-64.
2008: Bing Wang; J Li; Chunping Qiao; Chunlian Chen; P Hu; Xinmei Zhu; Liqiao Zhou; Janet Bogan; Joe Kornegay; Xiao Xiao
A canine minidystrophin is functional and therapeutic in mdx mice.
Gene therapy 2008;15(15):1099-106.
2008: Chunping Qiao; J Li; Jiangang Jiang; Xiaodong Zhu; Bing Wang; Juan Li; Xiao Xiao
Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice.
Human gene therapy 2008;19(3):241-54.
2006: Zhong Wang; Tong Zhu; Khaja K Rehman; Suzanne Bertera; Jian Zhang; Chunlian Chen; Glenn D Papworth; simon simon watkins; Massimo Trucco; Paul D Robbins; J Li; Xiao Xiao
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes.
Diabetes 2006;55(4):875-84.
2006: Romesh A Draviam; Bing Wang; J Li; Xiao Xiao; simon simon watkins
Mini-dystrophin efficiently incorporates into the dystrophin protein complex in living cells.
Journal of muscle research and cell motility 2006;27(1):53-67.
2005: Xiaojing Ye; Tong Zhu; Sheldon Bastacky; Teresa McHale; J Li; Xiao Xiao
Prevention and reversal of lupus in NZB/NZW mice by costimulatory blockade with adeno-associated virus-mediated gene transfer.
Arthritis and rheumatism 2005;52(12):3975-86.
2005: Tong Zhu; Liqiao Zhou; Satsuki Mori; Zhong Wang; Charles F McTiernan; Chunping Qiao; Chunlian Chen; Dao Wen Wang; J Li; Xiao Xiao
Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer.
Circulation 2005;112(17):2650-9.
2005: Khaja K Rehman; Zhiliang Wang; Rita Bottino; AN Balamurugan; Massimo Trucco; J Li; Xiao Xiao; Paul D Robbins
Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors.
Gene therapy 2005;12(17):1313-23.
2005: Chunping Qiao; J Li; Tong Zhu; Romesh A Draviam; simon simon watkins; Xiaojing Ye; Chunlian Chen; Juan Li; Xiao Xiao
Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(34):11999-2004.
2005: Roberto Bilbao; Daniel P Reay; J Li; Xiao Xiao; Paula R Clemens
Patterns of gene expression from in utero delivery of adenoviral-associated vector serotype 1.
Human gene therapy 2005;16(6):678-84.
2005: christian lattermann; William M Oxner; Xiao Xiao; J Li; Lars G Gilbertson; Paul D Robbins; James D Kang
The adeno associated viral vector as a strategy for intradiscal gene transfer in immune competent and pre-exposed rabbits.
Spine 2005;30(5):497-504.
2005: Zhong Wang; Tong Zhu; Chunping Qiao; Liqiao Zhou; Bing Wang; Jian Zhang; Chunlian Chen; J Li; Xiao Xiao
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart.
Nature biotechnology 2005;23(3):321-8.
2004: Guodong Cao; Michael Xiao; Fengyan Sun; Xiao Xiao; Wei Pei; J Li; Steven H Graham; Roger P. Simon; Jun Chen
Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(27):6189-201.
2003: Zhiliang Wang; Hsin-I Ma; J Li; L Sun; Junlan Zhang; Xiao Xiao
Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo.
Gene therapy 2003;10(26):2105-11.
2003: J Li; Dazhi Wang; Shiguang Qian; Zongyou Chen; Tong Zhu; Xiao Xiao
Efficient and long-term intracardiac gene transfer in delta-sarcoglycan-deficiency hamster by adeno-associated virus-2 vectors.
Gene therapy 2003;10(21):1807-13.
2003: Zongyou Chen; Lina Lu; J Li; Xiao Xiao; John J Fung; Shiguang Qian
Prolonged survival of heart allografts transduced with AAV-CTLA4Ig.
Microsurgery 2003;23(5):489-93.
2002: Chunping Qiao; Bing Wang; Xiaodong Zhu; J Li; Xiao Xiao
A novel gene expression control system and its use in stable, high-titer 293 cell-based adeno-associated virus packaging cell lines.
Journal of virology 2002;76(24):13015-27.
2002: Hsin-I Ma; Ping Guo; J Li; Shinn-Zong Lin; Yung-Hsiao Chiang; Xiao Xiao; Shi-Yuan Cheng
Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin.
Cancer research 2002;62(3):756-63.
2002: Chunping Qiao; J Li; Anna Skold; Xudong Zhang; Xiao Xiao
Feasibility of generating adeno-associated virus packaging cell lines containing inducible adenovirus helper genes.
Journal of virology 2002;76(4):1904-13.
2002: Hsin-I Ma; Shinn-Zong Lin; Yung-Hsiao Chiang; J Li; Show-Li Chen; Yeou-Ping Tsao; Xiao Xiao
Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector.
Gene therapy 2002;9(1):2-11.
2001: Dai-Wu Seol; J Li; M H Seol; Sang-Youel Park; Robert Talanian; Timothy R Billiar
Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis.
Cancer research 2001;61(3):1138-43.
2000: L Sun; J Li; Xiao Xiao
Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization.
Nature medicine 2000;6(5):599-602.
2000: Xiao Xiao; J Li; Yeou-Ping Tsao; D Dressman; Eric Hoffman; Jon F Watchko
Full functional rescue of a complete muscle (TA) in dystrophic hamsters by adeno-associated virus vector-directed gene therapy.
Journal of virology 2000;74(3):1436-42.
1999: J Li; D Dressman; Yeou-Ping Tsao; A Sakamoto; Eric Hoffman; Xiao Xiao
rAAV vector-mediated sarcogylcan gene transfer in a hamster model for limb girdle muscular dystrophy.
Gene therapy 1999;6(1):74-82.
1998: Xiao Xiao; J Li; R Jude Samulski
Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus.
Journal of virology 1998;72(3):2224-32.
1997: J Li; R Jude Samulski; Xiao Xiao
Role for highly regulated rep gene expression in adeno-associated virus vector production.
Journal of virology 1997;71(7):5236-43.
1997: Xiao Xiao; Thomas J McCown; J Li; George R Breese; A Leslie Morrow; R Jude Samulski
Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity.
Brain research 1997;756(1-2):76-83.
1997: Xiao Xiao; J Li; Thomas J McCown; R Jude Samulski
Gene transfer by adeno-associated virus vectors into the central nervous system.
Experimental neurology 1997;144(1):113-24.
1997: Xiao Xiao; Weidong Xiao; J Li; R Jude Samulski
A novel 165-base-pair terminal repeat sequence is the sole cis requirement for the adeno-associated virus life cycle.
Journal of virology 1997;71(2):941-8.
1996: Xiao Xiao; J Li; R Jude Samulski
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector.
Journal of virology 1996;70(11):8098-108.
1996: Thomas J McCown; Xiao Xiao; J Li; George R Breese; R Jude Samulski
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector.
Brain research 1996;713(1-2):99-107.