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Qiang Li

Research Profile

Chemicals & Drugs

Disorders

Polycystic Kidney, Autosomal Dominant

Procedures

Anatomy

Living Beings

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Publications

TOP 3
Qian Wang; Xiao-Qing Dai; Qiang Li; Shayla S Li; Gengqing Liang; Jagdeep Tuli; Xing-Zhen Chen
Filamin interacts with epithelial sodium channel and inhibits its channel function.
Jungwoo Yang; Wang Zheng; Xiao-Qing Dai; Shaimaa Hussein; Qiang Li; Xiao-Gai Li; Shiva Shafiei; Patrick Y Shen; Jian-Cheng Tu; Jagdeep Tuli; Qian Wang; Yuliang Wu; Xing-Zhen Chen
Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.
Qian Wang; Zuocheng Wang; María del Rocío Cantero; Horacio F Cantiello; Xiao-Qing Dai; Qiang Li; Shu Li; Ji Shen; Jian-Cheng Tu; Xing-Zhen Chen
Structural interaction and functional regulation of polycystin-2 by filamin.

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All Publications

2013: Qian Wang; Xiao-Qing Dai; Qiang Li; Shayla S Li; Gengqing Liang; Jagdeep Tuli; Xing-Zhen Chen
Filamin interacts with epithelial sodium channel and inhibits its channel function.
The Journal of biological chemistry 2013;288(1):264-73.
2012: Jungwoo Yang; Wang Zheng; Xiao-Qing Dai; Shaimaa Hussein; Qiang Li; Xiao-Gai Li; Shiva Shafiei; Patrick Y Shen; Jian-Cheng Tu; Jagdeep Tuli; Qian Wang; Yuliang Wu; Xing-Zhen Chen
Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.
The Journal of biological chemistry 2012;287(9):6551-61.
2012: Qian Wang; Zuocheng Wang; María del Rocío Cantero; Horacio F Cantiello; Xiao-Qing Dai; Qiang Li; Shu Li; Ji Shen; Jian-Cheng Tu; Xing-Zhen Chen
Structural interaction and functional regulation of polycystin-2 by filamin.
PloS one 2012;7(7):e40448.
2008: Genqing Liang; JungWoo Yang; Zuocheng Wang; Qiang Li; Yan Tang; Xing-Zhen Chen
Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha.
Human molecular genetics 2008;17(20):3254-62.
2008: Xing-Zhen Chen; Qiang Li; Yuliang Wu; Genqing Liang; Carlos J Lara; Horacio F Cantiello
Submembraneous microtubule cytoskeleton: interaction of TRPP2 with the cell cytoskeleton.
The FEBS journal 2008;275(19):4675-83.
2008: Genqing Liang; Qiang Li; Yan Tang; Koichi Kokame; Tadashi Kikuchi; Guanqing Wu; Xing-Zhen Chen
Polycystin-2 is regulated by endoplasmic reticulum-associated degradation.
Human molecular genetics 2008;17(8):1109-19.
2007: Qiang Li; Xiao-Qing Dai; Patrick Y Shen; Yuliang Wu; Wentong Long; Carl X Chen; Zahir Hussain; Shaohua Wang; Xing-Zhen Chen
Direct binding of alpha-actinin enhances TRPP3 channel activity.
Journal of neurochemistry 2007;103(6):2391-400.
2007: Xiao-Qing Dai; Alkarim Ramji; Yan Liu; Qiang Li; Edward Karpinski; Xing-Zhen Chen
Inhibition of TRPP3 channel by amiloride and analogs.
Molecular pharmacology 2007;72(6):1576-85.
2007: Nicolas Montalbetti; Qiang Li; Yuliang Wu; Xing-Zhen Chen; Horacio F Cantiello
Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures.
The Journal of physiology 2007;579(Pt 3):717-28.
2007: Yuliang Wu; Qiang Li; Xing-Zhen Chen
Detecting protein-protein interactions by Far western blotting.
Nature protocols 2007;2(12):3278-84.
2006: Qiang Li; Nicolas Montalbetti; Yuliang Wu; Arnolt Ramos; Malay K Raychowdhury; Xing-Zhen Chen; Horacio F Cantiello
Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.
The Journal of biological chemistry 2006;281(49):37566-75.
2006: Yuliang Wu; Xiao-Qing Dai; Qiang Li; Carl X Chen; Weiyi Mai; Zahir Hussain; Wentong Long; Nicolas Montalbetti; Guochun Li; Richard J Glynne; Shaohua Wang; Horacio F Cantiello; Guanqing Wu; Xing-Zhen Chen
Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin.
Human molecular genetics 2006;15(22):3280-92.
2006: Fang Li; Xiao-Qing Dai; Qiang Li; Yuliang Wu; Xing-Zhen Chen
Inhibition of polycystin-L channel by the Chinese herb Sparganum stoloniferum Buch.-Ham.
Canadian journal of physiology and pharmacology 2006;84(8-9):923-7.
2005: Nicolas Montalbetti; Qiang Li; Silvia González-Perrett; Jimena Semprine; Xing-Zhen Chen; Horacio F Cantiello
Effect of hydro-osmotic pressure on polycystin-2 channel function in the human syncytiotrophoblast.
Pflügers Archiv : European journal of physiology 2005;451(1):294-303.
2005: Nicolas Montalbetti; Qiang Li; Gustavo A Timpanaro; Silvia González-Perrett; Xiao-Qing Dai; Xing-Zhen Chen; Horacio F Cantiello
Cytoskeletal regulation of calcium-permeable cation channels in the human syncytiotrophoblast: role of gelsolin.
The Journal of physiology 2005;566(Pt 2):309-25.
2005: Qiang Li; Nicolas Montalbetti; Patrick Y Shen; Xiao-Qing Dai; Chris I Cheeseman; Edward Karpinski; Guanqing Wu; Horacio F Cantiello; Xing-Zhen Chen
Alpha-actinin associates with polycystin-2 and regulates its channel activity.
Human molecular genetics 2005;14(12):1587-603.
2004: Qiang Li; Xiao-Qing Dai; Patrick Y Shen; Horacio F Cantiello; Edward Karpinski; Xing-Zhen Chen
A modified mammalian tandem affinity purification procedure to prepare functional polycystin-2 channel.
FEBS letters 2004;576(1-2):231-6.
2004: Qiang Li; Andrei Manolescu; Mabel W L Ritzel; Sylvia Yao; Melissa D Slugoski; James D Young; Xing-Zhen Chen; Chris I Cheeseman
Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G236-42.
2003: Qiang Li; Yan Liu; Patrick Y Shen; Xiao-Qing Dai; Shaohua Wang; Lawrence B Smillie; Richard Sandford; Xing-Zhen Chen
Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
Biochemistry 2003;42(24):7618-25.
2003: Qiang Li; Yue Dai; Lei Guo; Yan Liu; Chunhai Hao; Guanqing Wu; Nuria Basora; Marek Michalak; Xing-Zhen Chen
Polycystin-2 associates with tropomyosin-1, an actin microfilament component.
Journal of molecular biology 2003;325(5):949-62.
2003: Qiang Li; Patrick Y Shen; Guanqing Wu; Xing-Zhen Chen
Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.
Biochemistry 2003;42(2):450-7.
2002: Yan Liu; Qiang Li; Miao Tan; Yu-Yang Zhang; Edward Karpinski; Jing Zhou; Xing-Zhen Chen
Modulation of the human polycystin-L channel by voltage and divalent cations.
FEBS letters 2002;525(1-3):71-6.
2002: Qiang Li; Yan Liu; Wei Zhao; Xing-Zhen Chen
The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation.
FEBS letters 2002;516(1-3):270-8.