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Yechezkel Barenholz
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18
Gabizon, Alberto
15
Kedar, Eli
9
Eliyahu, Hagit
8
Hirsch-Lerner, Danielle
8
Joseph, Aviva
7
Even-Chen, Simcha
7
Domb, Abraham
7
Goren, Dorit
7
Babai, Ilan
6
Samuni, Amram
6
Simberg, Dmitri
6
Talmon, Yeshayahu
6
Zakay-Rones, Zichria
6
Zuidam, NJ
5
Tirosh, Oren
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All Publications
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2009: Schroeder Avi; Kost Joseph; Barenholz Yechezkel
Ultrasound, liposomes, and drug delivery: principles for using ultrasound to control the release of drugs from liposomes.
Chemistry and physics of lipids 2009;162(1-2):1-16.
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2009: Zucker Daniel; Marcus David; Barenholz Yechezkel; Goldblum Amiram
Liposome drugs' loading efficiency: a working model based on loading conditions and drug's physicochemical properties.
Journal of controlled release : official journal of the Controlled Release Society 2009;139(1):73-80.
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2009: Kizelsztein Pablo; Ovadia Haim; Garbuzenko Olga; Sigal Alex; Barenholz Yechezkel
Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2009;213(1-2):20-5.
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2009: Tirosh Boaz; Khatib Nadine; Barenholz Yechezkel; Nissan Aviram; Rubinstein Abraham
Transferrin as a luminal target for negatively charged liposomes in the inflamed colonic mucosa.
Molecular pharmaceutics 2009;6(4):1083-91.
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2009: Schroeder Avi; Honen Reuma; Turjeman Keren; Gabizon Alberto; Kost Joseph; Barenholz Yechezkel
Ultrasound triggered release of cisplatin from liposomes in murine tumors.
Journal of controlled release : official journal of the Controlled Release Society 2009;137(1):63-8.
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2009: Waknine-Grinberg Judith Hannah; El-On Joseph; Barak Vivian; Barenholz Yechezkel; Golenser Jacob
The immunomodulatory effect of Sambucol on leishmanial and malarial infections.
Planta medica 2009;75(6):581-6.
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2008: Schroeder Avi; Sigal Alex; Turjeman Keren; Barenholz Yechezkel
Using PEGylated nano-liposomes to target tissue invaded by a foreign body.
Journal of drug targeting 2008;16(7):591-5.
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2008: Khazanov Elena; Priev Aba; Shillemans Joris P; Barenholz Yechezkel
Physicochemical and biological characterization of ceramide-containing liposomes: paving the way to ceramide therapeutic application.
Langmuir : the ACS journal of surfaces and colloids 2008;24(13):6965-80.
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2008: Avnir Yuval; Ulmansky Rina; Wasserman Veronica; Even-Chen Simcha; Broyer Maya; Barenholz Yechezkel; Naparstek Yaakov
Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: a novel approach to treating autoimmune arthritis.
Arthritis and rheumatism 2008;58(1):119-29.
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2007: Boktov Julia; Hirsch-Lerner Danielle; Barenholz Yechezkel
Characterization of the interplay between the main factors contributing to lipoplex-mediated transfection in cell cultures.
The journal of gene medicine 2007;9(10):884-93.
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2007: Eliyahu H; Joseph A; Schillemans J P; Azzam T; Domb A J; Barenholz Y
Characterization and in vivo performance of dextran-spermine polyplexes and DOTAP/cholesterol lipoplexes administered locally and systemically.
Biomaterials 2007;28(14):2339-49.
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2007: Schroeder Avi; Avnir Yuval; Weisman Sarah; Najajreh Yousef; Gabizon Alberto; Talmon Yeshayahu; Kost Joseph; Barenholz Yechezkel
Controlling liposomal drug release with low frequency ultrasound: mechanism and feasibility.
Langmuir : the ACS journal of surfaces and colloids 2007;23(7):4019-25.
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2007: Wasserman Veronica; Kizelsztein Pablo; Garbuzenko Olga; Kohen Ron; Ovadia Haim; Tabakman Rinat; Barenholz Yechezkel
The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release.
Langmuir : the ACS journal of surfaces and colloids 2007;23(4):1937-47.
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2007: Szebeni János; Alving Carl R; Rosivall László; Bünger Rolf; Baranyi Lajos; Bedöcs Péter; Tóth Miklós; Barenholz Yezheckel
Animal models of complement-mediated hypersensitivity reactions to liposomes and other lipid-based nanoparticles.
Journal of liposome research 2007;17(2):107-17.
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2006: Khazanov Elena; Simberg Dmitri; Barenholz Yechezkel
Lipoplexes prepared from cationic liposomes and mammalian DNA induce CpG-independent, direct cytotoxic effects in cell cultures and in mice.
The journal of gene medicine 2006;8(8):998-1007.
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2006: Najajreh Yousef; Ardeli-Tzaraf Yael; Kasparkova Jana; Heringova Pavla; Prilutski Dmitri; Balter Liliana; Jawbry Seba; Khazanov Elena; Perez Jose Manuel; Barenholz Yechezkel; Brabec Viktor; Gibson Dan
Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles.
Journal of medicinal chemistry 2006;49(15):4674-83.
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2006: Najajreh Yousef; Khazanov Elena; Jawbry Seba; Ardeli-Tzaraf Yael; Perez Jose Manuel; Kasparkova Jana; Brabec Viktor; Barenholz Yechezkel; Gibson Dan
Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies.
Journal of medicinal chemistry 2006;49(15):4665-73.
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2006: Mitchell Leslie Ann; Joseph Aviva; Kedar Eli; Barenholz Yechezkel; Galun Eitan
Mucosal immunization against hepatitis A: antibody responses are enhanced by co-administration of synthetic oligodeoxynucleotides and a novel cationic lipid.
Vaccine 2006;24(25):5300-10.
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2006: Joseph Aviva; Itskovitz-Cooper Noga; Samira Sarit; Flasterstein Orli; Eliyahu Hagit; Simberg Dmitri; Goldwaser Itzik; Barenholz Yechezkel; Kedar Eli
A new intranasal influenza vaccine based on a novel polycationic lipid--ceramide carbamoyl-spermine (CCS) I. Immunogenicity and efficacy studies in mice.
Vaccine 2006;24(18):3990-4006.
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2006: Jubeh Tareq Taha; Nadler-Milbauer Mirela; Barenholz Yechezkel; Rubinstein Abraham
Local treatment of experimental colitis in the rat by negatively charged liposomes of catalase, TMN and SOD.
Journal of drug targeting 2006;14(3):155-63.
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2006: Eliyahu Hagit; Siani Shahar; Azzam Tony; Domb Abraham J; Barenholz Yechezkel
Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates.
Biomaterials 2006;27(8):1646-55.
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2006: Eliyahu Hagit; Joseph Aviva; Azzam Tony; Barenholz Yechezkel; Domb Abraham J
Dextran-spermine-based polyplexes--evaluation of transgene expression and of local and systemic toxicity in mice.
Biomaterials 2006;27(8):1636-45.
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2006: Meidan Victor M; Glezer Judith; Salomon Sharona; Sidi Yechezkel; Barenholz Yechezkel; Cohen Jack S; Lilling Gila
Specific lipoplex-mediated antisense against Bcl-2 in breast cancer cells: a comparison between different formulations.
Journal of liposome research 2006;16(1):27-43.
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2005: Avnir Yuval; Barenholz Yechezkel
pH determination by pyranine: medium-related artifacts and their correction.
Analytical biochemistry 2005;347(1):34-41.
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2005: Simberg Dmitri; Weiss Aryeh; Barenholz Yechezkel
Reversible mode of binding of serum proteins to DOTAP/cholesterol Lipoplexes: a possible explanation for intravenous lipofection efficiency.
Human gene therapy 2005;16(9):1087-96.
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2005: Hirsch-Lerner Danielle; Zhang Ming; Eliyahu Hagit; Ferrari Marylin E; Wheeler Carl J; Barenholz Yechezkel
Effect of "helper lipid" on lipoplex electrostatics.
Biochimica et biophysica acta 2005;1714(2):71-84.
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2005: Baru Moshe; Carmel-Goren Lea; Barenholz Yechezkel; Dayan Inbal; Ostropolets Savely; Slepoy Igal; Gvirtzer Nira; Fukson Vladimir; Spira Jack
Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy.
Thrombosis and haemostasis 2005;93(6):1061-8.
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2005: Garbuzenko Olga; Barenholz Yechezkel; Priev Aba
Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer.
Chemistry and physics of lipids 2005;135(2):117-29.
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2005: Najajreh Yousef; Prilutski Dmitri; Ardeli-Tzaraf Yael; Perez Jose Manuel; Khazanov Elena; Barenholz Yechezkel; Kasparkova Jana; Brabec Viktor; Gibson Dan
Structure and unique interactions with DNA of a cationic trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand.
Angewandte Chemie (International ed. in English) 2005;44(19):2885-7.
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2005: Garbuzenko Olga; Zalipsky Samuel; Qazen Masoud; Barenholz Yechezkel
Electrostatics of PEGylated micelles and liposomes containing charged and neutral lipopolymers.
Langmuir : the ACS journal of surfaces and colloids 2005;21(6):2560-8.
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2005: Eliyahu H; Makovitzki A; Azzam T; Zlotkin A; Joseph A; Gazit D; Barenholz Y; Domb A J
Novel dextran-spermine conjugates as transfecting agents: comparing water-soluble and micellar polymers.
Gene therapy 2005;12(6):494-503.
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2005: Jubeh Tareq Taha; Antler Sivan; Haupt Susan; Barenholz Yechezkel; Rubinstein Abraham
Local prevention of oxidative stress in the intestinal epithelium of the rat by adhesive liposomes of superoxide dismutase and tempamine.
Molecular pharmaceutics 2005;2(1):2-11.
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2005: Eliyahu H; Barenholz Y; Domb A J
Polymers for DNA delivery.
Molecules (Basel, Switzerland) 2005;10(1):34-64.
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2004: Kalmanzon Eliahu; Rahamim Yocheved; Carmeli Shmuel; Barenholz Yechezkel; Zlotkin Eliahu
Endogenous regulation of the functional duality of pahutoxin, a marine trunkfish surfactant.
Toxicon : official journal of the International Society on Toxinology 2004;44(8):939-42.
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2004: Weisman Sarah; Hirsch-Lerner Danielle; Barenholz Yechezkel; Talmon Yeshayahu
Nanostructure of cationic lipid-oligonucleotide complexes.
Biophysical journal 2004;87(1):609-14.
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2004: Grant Gilbert J; Barenholz Yechezkel; Bolotin Elijah M; Bansinath Mylarrao; Turndorf Herman; Piskoun Boris; Davidson Elyad M
A novel liposomal bupivacaine formulation to produce ultralong-acting analgesia.
Anesthesiology 2004;101(1):133-7.
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2004: Jubeh Tareq Taha; Barenholz Yechezkel; Rubinstein Abraham
Differential adhesion of normal and inflamed rat colonic mucosa by charged liposomes.
Pharmaceutical research 2004;21(3):447-53.
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2004: Simberg Dmitri; Weisman Sarah; Talmon Yeshayahu; Barenholz Yechezkel
DOTAP (and other cationic lipids): chemistry, biophysics, and transfection.
Critical reviews in therapeutic drug carrier systems 2004;21(4):257-317.
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2004: Barenholz Yechezkel
Sphingomyelin and cholesterol: from membrane biophysics and rafts to potential medical applications.
Sub-cellular biochemistry 2004;37():167-215.
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2004: Samuni Ayelet M; Barenholz Yechezkel
Use of nitroxides to protect liposomes against oxidative damage.
Methods in enzymology 2004;387():299-314.
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2003: Simberg Dmitri; Weisman Sarah; Talmon Yeshayahu; Faerman Alexander; Shoshani Tzipora; Barenholz Yechezkel
The role of organ vascularization and lipoplex-serum initial contact in intravenous murine lipofection.
The Journal of biological chemistry 2003;278(41):39858-65.
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2003: Kalmanzon Eliahu; Rahamim Yocheved; Barenholz Yechezkel; Carmeli Shmuel; Zlotkin Eliahu
Receptor-mediated toxicity of pahutoxin, a marine trunkfish surfactant.
Toxicon : official journal of the International Society on Toxinology 2003;42(1):63-71.
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2003: Ben-Yehuda Arie; Joseph Aviva; Barenholz Yechezkel; Zeira Evelyne; Even-Chen Simcha; Louria-Hayon Igal; Babai Ilan; Zakay-Rones Zichria; Greenbaum Evgenia; Galprin Ilia; Glück Reinhard; Zurbriggen Rinaldo; Kedar Eli
Immunogenicity and safety of a novel IL-2-supplemented liposomal influenza vaccine (INFLUSOME-VAC) in nursing-home residents.
Vaccine 2003;21(23):3169-78.
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2003: Barenholz Ayelet; Fishel Fanny; Yakir Elisheva; Gatt Shimon; Barenholz Yechezekel; Bercovier Hervé
Liposomes enhance bioremediation of oil-contaminated soil.
Journal of liposome research 2003;13(2):173-86.
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2003: Ben-Yehuda Arie; Joseph Aviva; Zeira Evelyne; Even-Chen Simcha; Louria-Hayon Igal; Babai Ilan; Zakay-Rones Zichria; Greenbaum Evgenia; Barenholz Yechezkel; Kedar Eli
Immunogenicity and safety of a novel liposomal influenza subunit vaccine (INFLUSOME-VAC) in young adults.
Journal of medical virology 2003;69(4):560-7.
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2003: Barenholz Yechezkel
Relevancy of drug loading to liposomal formulation therapeutic efficacy.
Journal of liposome research 2003;13(1):1-8.
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2003: Samuni Ayelet M; Barenholz Yechezkel
Site-activity relationship of nitroxide radical's antioxidative effect.
Free radical biology & medicine 2003;34(2):177-85.
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2003: Shmeeda Hilary; Even-Chen Simcha; Honen Reuma; Cohen Rivka; Weintraub Carmela; Barenholz Yechezkel
Enzymatic assays for quality control and pharmacokinetics of liposome formulations: comparison with nonenzymatic conventional methodologies.
Methods in enzymology 2003;367():272-92.
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2003: Gabizon Alberto; Shmeeda Hilary; Barenholz Yechezkel
Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies.
Clinical pharmacokinetics 2003;42(5):419-36.
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2002: Khazanov Elena; Barenholz Yechezkel; Gibson Dan; Najajreh Yousef
Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization.
Journal of medicinal chemistry 2002;45(24):5196-204.
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2002: Joseph Aviva; Louria-Hayon Igal; Plis-Finarov Alla; Zeira Evelyne; Zakay-Rones Zichria; Raz Eyal; Hayashi Tomoko; Takabayashi Kenji; Barenholz Yechezkel; Kedar Eli
Liposomal immunostimulatory DNA sequence (ISS-ODN): an efficient parenteral and mucosal adjuvant for influenza and hepatitis B vaccines.
Vaccine 2002;20(27-28):3342-54.
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2002: Shmeeda Hilary; Kaspler Pavel; Shleyer Judith; Honen Reuma; Horowitz Michal; Barenholz Yechezkel
Heat acclimation in rats: modulation via lipid polyunsaturation.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;283(2):R389-99.
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2002: Eliyahu H; Servel N; Domb A J; Barenholz Y
Lipoplex-induced hemagglutination: potential involvement in intravenous gene delivery.
Gene therapy 2002;9(13):850-8.
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2002: Azzam Tony; Eliyahu Hagit; Shapira Libi; Linial Michal; Barenholz Yechezkel; Domb Abraham J
Polysaccharide-oligoamine based conjugates for gene delivery.
Journal of medicinal chemistry 2002;45(9):1817-24.
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2002: Szebeni J; Baranyi L; Savay S; Milosevits J; Bunger R; Laverman P; Metselaar J M; Storm G; Chanan-Khan A; Liebes L; Muggia F M; Cohen R; Barenholz Y; Alving C R
Role of complement activation in hypersensitivity reactions to doxil and hynic PEG liposomes: experimental and clinical studies.
Journal of liposome research 2002;12(1-2):165-72.
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2001: Meidan V M; Glezer J; Amariglio N; Cohen J S; Barenholz Y
Oligonucleotide lipoplexes: the influence of oligonucleotide composition on complexation.
Biochimica et biophysica acta 2001;1568(3):177-82.
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2001: Simberg D; Danino D; Talmon Y; Minsky A; Ferrari M E; Wheeler C J; Barenholz Y
Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity.
The Journal of biological chemistry 2001;276(50):47453-9.
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2001: Babai I; Barenholz Y; Zakay-Rones Z; Greenbaum E; Samira S; Hayon I; Rochman M; Kedar E
A novel liposomal influenza vaccine (INFLUSOME-VAC) containing hemagglutinin-neuraminidase and IL-2 or GM-CSF induces protective anti-neuraminidase antibodies cross-reacting with a wide spectrum of influenza A viral strains.
Vaccine 2001;20(3-4):505-15.
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2001: Kerner M; Meyuhas O; Hirsch-Lerner D; Rosen L J; Min Z; Barenholz Y
Interplay in lipoplexes between type of pDNA promoter and lipid composition determines transfection efficiency of human growth hormone in NIH3T3 cells in culture.
Biochimica et biophysica acta 2001;1532(1-2):128-36.
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2001: Szebeni J; Alving C R; Savay S; Barenholz Y; Priev A; Danino D; Talmon Y
Formation of complement-activating particles in aqueous solutions of Taxol: possible role in hypersensitivity reactions.
International immunopharmacology 2001;1(4):721-35.
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2001: Grant G J; Barenholz Y; Piskoun B; Bansinath M; Turndorf H; Bolotin E M
DRV liposomal bupivacaine: preparation, characterization, and in vivo evaluation in mice.
Pharmaceutical research 2001;18(3):336-43.
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2001: Kalmanzon E; Aknin-Herrman R; Rahamim Y; Carmeli S; Barenholz Y; Zlotkin E
Cooperative cocktail in a chemical defence mechanism of a trunkfish.
Cellular & molecular biology letters 2001;6(4):971-84.
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2000: Even-Chen S; Barenholz Y
DOTAP cationic liposomes prefer relaxed over supercoiled plasmids.
Biochimica et biophysica acta 2000;1509(1-2):176-88.
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2000: Samuni A M; Lipman A; Barenholz Y
Damage to liposomal lipids: protection by antioxidants and cholesterol-mediated dehydration.
Chemistry and physics of lipids 2000;105(2):121-34.
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2000: Meidan V M; Cohen J S; Amariglio N; Hirsch-Lerner D; Barenholz Y
Interaction of oligonucleotides with cationic lipids: the relationship between electrostatics, hydration and state of aggregation.
Biochimica et biophysica acta 2000;1464(2):251-61.
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2000: Kedar E; Gur H; Babai I; Samira S; Even-Chen S; Barenholz Y
Delivery of cytokines by liposomes: hematopoietic and immunomodulatory activity of interleukin-2 encapsulated in conventional liposomes and in long-circulating liposomes.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(1):131-45.
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1999: Samet D; Barenholz Y
Characterization of acidic and neutral sphingomyelinase activities in crude extracts of HL-60 cells.
Chemistry and physics of lipids 1999;102(1-2):65-77.
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1999: Barenholz Y; Thompson T E
Sphingomyelin: biophysical aspects.
Chemistry and physics of lipids 1999;102(1-2):29-34.
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1999: Hirsch-Lerner D; Barenholz Y
Hydration of lipoplexes commonly used in gene delivery: follow-up by laurdan fluorescence changes and quantification by differential scanning calorimetry.
Biochimica et biophysica acta 1999;1461(1):47-57.
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1999: Zuidam N J; Barenholz Y; Minsky A
Chiral DNA packaging in DNA-cationic liposome assemblies.
FEBS letters 1999;457(3):419-22.
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1999: Diminsky D; Moav N; Gorecki M; Barenholz Y
Physical, chemical and immunological stability of CHO-derived hepatitis B surface antigen (HBsAg) particles.
Vaccine 1999;18(1-2):3-17.
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1999: Naslavsky N; Shmeeda H; Friedlander G; Yanai A; Futerman A H; Barenholz Y; Taraboulos A
Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions.
The Journal of biological chemistry 1999;274(30):20763-71.
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1999: Zuidam N J; Hirsch-Lerner D; Margulies S; Barenholz Y
Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency.
Biochimica et biophysica acta 1999;1419(2):207-20.
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1999: Bandak S; Ramu A; Barenholz Y; Gabizon A
Reduced UV-induced degradation of doxorubicin encapsulated in polyethyleneglycol-coated liposomes.
Pharmaceutical research 1999;16(6):841-6.
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1999: Zuidam N J; Barenholz Y
Characterization of DNA-lipid complexes commonly used for gene delivery.
International journal of pharmaceutics 1999;183(1):43-6.
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1999: Korablyov V; Zimran A; Barenholz Y
Cerebroside-beta-glucosidase encapsulation in liposomes for Gaucher's disease treatment revisited.
Pharmaceutical research 1999;16(3):466-9.
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1999: Babai I; Samira S; Barenholz Y; Zakay-Rones Z; Kedar E
A novel influenza subunit vaccine composed of liposome-encapsulated haemagglutinin/neuraminidase and IL-2 or GM-CSF. II. Induction of TH1 and TH2 responses in mice.
Vaccine 1999;17(9-10):1239-50.
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1999: Babai I; Samira S; Barenholz Y; Zakay-Rones Z; Kedar E
A novel influenza subunit vaccine composed of liposome-encapsulated haemagglutinin/neuraminidase and IL-2 or GM-CSF. I. Vaccine characterization and efficacy studies in mice.
Vaccine 1999;17(9-10):1223-38.
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1999: Cabanes A; Even-Chen S; Zimberoff J; Barenholz Y; Kedar E; Gabizon A
Enhancement of antitumor activity of polyethylene glycol-coated liposomal doxorubicin with soluble and liposomal interleukin 2.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):687-93.
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1999: Tirosh O; Katzhendler J; Barenholz Y; Kohen R
Low-density lipoprotein oxidation and its prevention by amidothionophosphate antioxidants.
Antioxidants & redox signaling 1999;1(3):325-38.
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1999: Tirosh O; Katzhendler Y; Barenholz Y; Kohen R
Antioxidant activity of amidothionophosphates.
Methods in enzymology 1999;299():293-300.
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1998: Clerc S; Barenholz Y
A quantitative model for using acridine orange as a transmembrane pH gradient probe.
Analytical biochemistry 1998;259(1):104-11.
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1998: Hirsch-Lerner D; Barenholz Y
Probing DNA-cationic lipid interactions with the fluorophore trimethylammonium diphenyl-hexatriene (TMADPH).
Biochimica et biophysica acta 1998;1370(1):17-30.
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1998: Tirosh O; Barenholz Y; Katzhendler J; Priev A
Hydration of polyethylene glycol-grafted liposomes.
Biophysical journal 1998;74(3):1371-9.
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1998: Zuidam N J; Barenholz Y
Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery.
Biochimica et biophysica acta 1998;1368(1):115-28.
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1997: Zuidam N J; Barenholz Y
Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin.
Biochimica et biophysica acta 1997;1329(2):211-22.
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1997: Tirosh O; Kohen R; Katzhendler J; Alon A; Barenholz Y
Oxidative stress effect on the integrity of lipid bilayers is modulated by cholesterol level of bilayers.
Chemistry and physics of lipids 1997;87(1):17-22.
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1997: Kedar E; Palgi O; Golod G; Babai I; Barenholz Y
Delivery of cytokines by liposomes. III. Liposome-encapsulated GM-CSF and TNF-alpha show improved pharmacokinetics and biological activity and reduced toxicity in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1997;20(3):180-93.
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1997: Diminsky D; Schirmbeck R; Reimann J; Barenholz Y
Comparison between hepatitis B surface antigen (HBsAg) particles derived from mammalian cells (CHO) and yeast cells (Hansenula polymorpha): composition, structure and immunogenicity.
Vaccine 1997;15(6-7):637-47.
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1997: Bar L K; Barenholz Y; Thompson T E
Effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers.
Biochemistry 1997;36(9):2507-16.
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1997: Eckstein M; Barenholz Y; Bar L K; Segal E
Liposomes containing Candida albicans ribosomes as a prophylactic vaccine against disseminated candidiasis in mice.
Vaccine 1997;15(2):220-4.
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1997: Samuni A M; Barenholz Y; Crommelin D J; Zuidam N J
Gamma-irradiation damage to liposomes differing in composition and their protection by nitroxides.
Free radical biology & medicine 1997;23(7):972-9.
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1997: Samuni A M; Barenholz Y
Stable nitroxide radicals protect lipid acyl chains from radiation damage.
Free radical biology & medicine 1997;22(7):1165-74.
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1996: Glick D; Barenholz Y
IgG immunoglobulins induce activation of the sphingomyelin cycle in HL-60 cells.
FEBS letters 1996;394(3):237-40.
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1996: Emanuel N; Kedar E; Bolotin E M; Smorodinsky N I; Barenholz Y
Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: pharmacokinetics and biodistribution in tumor-bearing mice.
Pharmaceutical research 1996;13(6):861-8.
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1996: Emanuel N; Kedar E; Bolotin E M; Smorodinsky N I; Barenholz Y
Preparation and characterization of doxorubicin-loaded sterically stabilized immunoliposomes.
Pharmaceutical research 1996;13(3):352-9.
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1996: Barenholz Y; Cohen T; Haas E; Ottolenghi M
Lateral organization of pyrene-labeled lipids in bilayers as determined from the deviation from equilibrium between pyrene monomers and excimers.
The Journal of biological chemistry 1996;271(6):3085-90.
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1996: Tirosh O; Katzhendler Y; Barenholz Y; Ginsburg I; Kohen R
Antioxidant properties of amidothionophosphates: novel antioxidant molecules.
Free radical biology & medicine 1996;20(3):421-32.
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1995: Clerc S; Barenholz Y
Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients.
Biochimica et biophysica acta 1995;1240(2):257-65.
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1995: Shmeeda H; Petkova D; Barenholz Y
Cholesterol distribution in rat heart myocytes.
The American journal of physiology 1995;268(2 Pt 2):H759-66.
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1995: Levy M Y; Polacheck I; Barenholz Y; Benita S
Efficacy evaluation of a novel submicron miconazole emulsion in a murine cryptococcosis model.
Pharmaceutical research 1995;12(2):223-30.
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1994: Shmeeda H; Petkova D; Barenholz Y
Cholesterol homeostasis in cultures of rat heart myocytes: relationship to cellular hypertrophy.
The American journal of physiology 1994;267(5 Pt 2):H1689-97.
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1994: Kedar E; Braun E; Rutkowski Y; Emanuel N; Barenholz Y
Delivery of cytokines by liposomes. II. Interleukin-2 encapsulated in long-circulating sterically stabilized liposomes: immunomodulatory and anti-tumor activity in mice.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(2):115-24.
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1994: Kedar E; Rutkowski Y; Braun E; Emanuel N; Barenholz Y
Delivery of cytokines by liposomes. I. Preparation and characterization of interleukin-2 encapsulated in long-circulating sterically stabilized liposomes.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(1):47-59.
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1994: Gabizon A; Catane R; Uziely B; Kaufman B; Safra T; Cohen R; Martin F; Huang A; Barenholz Y
Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes.
Cancer research 1994;54(4):987-92.
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1993: Haran G; Cohen R; Bar L K; Barenholz Y
Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases.
Biochimica et biophysica acta 1993;1151(2):201-15.
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1993: Borenstain-Ben Yashar V; Barenholz Y; Hy-Am E; Rachmilewitz E A; Eldor A
Phosphatidylserine in the outer leaflet of red blood cells from beta-thalassemia patients may explain the chronic hypercoagulable state and thrombotic episodes.
American journal of hematology 1993;44(1):63-5.
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1993: Amselem S; Cohen R; Barenholz Y
In vitro tests to predict in vivo performance of liposomal dosage forms.
Chemistry and physics of lipids 1993;64(1-3):219-37.
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1993: Borenstain V; Barenholz Y
Characterization of liposomes and other lipid assemblies by multiprobe fluorescence polarization.
Chemistry and physics of lipids 1993;64(1-3):117-27.
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1993: Barenholz Y; Amselem S; Goren D; Cohen R; Gelvan D; Samuni A; Golden E B; Gabizon A
Stability of liposomal doxorubicin formulations: problems and prospects.
Medicinal research reviews 1993;13(4):449-91.
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1993: Gabizon A A; Barenholz Y; Bialer M
Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycol-derivatized phospholipid: pharmacokinetic studies in rodents and dogs.
Pharmaceutical research 1993;10(5):703-8.
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1993: Barenholz Y; Pal R; Wagner R R
Metabolic labeling of viral membrane lipids by fluorescent fatty acids: studying virus fusion with target membranes.
Methods in enzymology 1993;220():288-312.
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1993: Levy M Y; Polacheck I; Barenholz Y; Benita S
Efficacy evaluation of a novel submicron amphotericin B emulsion in murine candidiasis.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1993;31(3):207-18.
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1993: Eldor A; Maclouf J; Lellouche F; Ben-Yashar V; Barenholz Y; Durst R; Hy-Am E; Goldfarb A; Rachmilewitz E
A chronic hypercoagulable state and life-long platelet activation in beta thalassemia major.
The Southeast Asian journal of tropical medicine and public health 1993;24 Suppl 1():92-5.
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1992: Horowitz A T; Barenholz Y; Gabizon A A
In vitro cytotoxicity of liposome-encapsulated doxorubicin: dependence on liposome composition and drug release.
Biochimica et biophysica acta 1992;1109(2):203-9.
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1991: Gabizon A; Chisin R; Amselem S; Druckmann S; Cohen R; Goren D; Fromer I; Peretz T; Sulkes A; Barenholz Y
Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycin.
British journal of cancer 1991;64(6):1125-32.
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1991: Ben-Yashar V; Barenholz Y
Characterization of the core and surface of human plasma lipoproteins. A study based on the use of five fluorophores.
Chemistry and physics of lipids 1991;60(1):1-14.
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1991: Barenholz Y; Cohen T; Korenstein R; Ottolenghi M
Organization and dynamics of pyrene and pyrene lipids in intact lipid bilayers. Photo-induced charge transfer processes.
Biophysical journal 1991;60(1):110-24.
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1990: Amselem S; Gabizon A; Barenholz Y
Optimization and upscaling of doxorubicin-containing liposomes for clinical use.
Journal of pharmaceutical sciences 1990;79(12):1045-52.
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1990: Goren D; Gabizon A; Barenholz Y
The influence of physical characteristics of liposomes containing doxorubicin on their pharmacological behavior.
Biochimica et biophysica acta 1990;1029(2):285-94.
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1989: Gabizon A; Peretz T; Sulkes A; Amselem S; Ben-Yosef R; Ben-Baruch N; Catane R; Biran S; Barenholz Y
Systemic administration of doxorubicin-containing liposomes in cancer patients: a phase I study.
European journal of cancer & clinical oncology 1989;25(12):1795-803.
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1989: Ben-Yashar V; Barenholz Y
The interaction of cholesterol and cholest-4-en-3-one with dipalmitoylphosphatidylcholine. Comparison based on the use of three fluorophores.
Biochimica et biophysica acta 1989;985(3):271-8.
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1989: Druckmann S; Gabizon A; Barenholz Y
Separation of liposome-associated doxorubicin from non-liposome-associated doxorubicin in human plasma: implications for pharmacokinetic studies.
Biochimica et biophysica acta 1989;980(3):381-4.
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1988: Gabizon A; Goren D; Barenholz Y
Investigations on the antitumor efficacy of liposome-associated doxorubicin in murine tumor models.
Israel journal of medical sciences 1988;24(9-10):512-7.
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1987: Ben Yashar V; Menashe M; Biltonen R L; Johnson M L; Barenholz Y
Interaction of trans-parinaric acid with phosphatidylcholine bilayers: comparison with the effect of other fluorophores.
Biochimica et biophysica acta 1987;904(1):117-24.
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1985: Gabizon A; Goren D; Fuks Z; Meshorer A; Barenholz Y
Superior therapeutic activity of liposome-associated adriamycin in a murine metastatic tumour model.
British journal of cancer 1985;51(5):681-9.
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1983: Gabizon A; Goren D; Fuks Z; Barenholz Y; Dagan A; Meshorer A
Enhancement of adriamycin delivery to liver metastatic cells with increased tumoricidal effect using liposomes as drug carriers.
Cancer research 1983;43(10):4730-5.
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1982: Gabizon A; Dagan A; Goren D; Barenholz Y; Fuks Z
Liposomes as in vivo carriers of adriamycin: reduced cardiac uptake and preserved antitumor activity in mice.
Cancer research 1982;42(11):4734-9.
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