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Bertrand Liagre

Research Profile

Chemicals & Drugs

Anatomy

Procedures

Field Flow Fractionation

Disorders

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Publications

TOP 3
Lamia Ghezali; David LEGER; Jean-Louis Beneytout; Jeanne Cook-Moreau; Youness Limami; Bertrand Liagre
Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect.
Youness Limami; Emilie Pinault; Aline Pinon; Alain Simon; Jean-Louis Beneytout; Christiane Delage; David LEGER; Bertrand Liagre
The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.
Aline Pinon; Jeanne Cook-Moreau; Christiane Delage; RAPHAEL EMMANUEL DUVAL; Bertrand Liagre; Youness Limami; Ludovic Micallef; Alain Simon
A novel form of melanoma apoptosis resistance: melanogenesis up-regulation in apoptotic B16-F0 cells delays ursolic acid-triggered cell death.

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All Publications

2013: Lamia Ghezali; David LEGER; Jean-Louis Beneytout; Jeanne Cook-Moreau; Youness Limami; Bertrand Liagre
Cyclopamine and jervine induce COX-2 overexpression in human erythroleukemia cells but only cyclopamine has a pro-apoptotic effect.
Experimental cell research 2013;319(7):1043-53.
2012: Youness Limami; Emilie Pinault; Aline Pinon; Alain Simon; Jean-Louis Beneytout; Christiane Delage; David LEGER; Bertrand Liagre
The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.
Biochimie 2012;94(8):1754-63.
2011: Aline Pinon; Jeanne Cook-Moreau; Christiane Delage; RAPHAEL EMMANUEL DUVAL; Bertrand Liagre; Youness Limami; Ludovic Micallef; Alain Simon
A novel form of melanoma apoptosis resistance: melanogenesis up-regulation in apoptotic B16-F0 cells delays ursolic acid-triggered cell death.
Experimental cell research 2011;317(12):1669-76.
2011: Youness Limami; Aline Pinon; David Yannick Leger; Yoanne Mousseau; Jeanne Cook-Moreau; Jean-Louis Beneytout; Christiane Delage; Bertrand Liagre; Alain Simon
HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death.
Biochimie 2011;93(4):749-57.
2011: C Lepage; David Yannick Léger; J Bertrand; F Martin; Jean-Louis Beneytout; Bertrand Liagre
Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells.
Cancer letters 2011;301(2):193-202.
2010: Clementine Cailleteau; Ludovic Micallef; Clemence Lepage; P J P Cardot; Jean-Louis Beneytout; Bertrand Liagre; Serge Battu
Investigating the relationship between cell cycle stage and diosgenin-induced megakaryocytic differentiation of HEL cells using sedimentation field-flow fractionation.
Analytical and bioanalytical chemistry 2010;398(3):1273-83.
2010: Clemence Lepage; Bertrand Liagre; Jeanne Cook-Moreau; Aline Pinon; Jean-Louis Beneytout
Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells.
International journal of oncology 2010;36(5):1183-91.
2009: G Bégaud-Grimaud; Serge Battu; Bertrand Liagre; Jean-Louis Beneytout; Marie-Odile Jauberteau; P J P Cardot
Development of a downscale sedimentation field flow fractionation device for biological event monitoring.
Journal of chromatography. A 2009;1216(52):9125-33.
2009: Wahid Chaouki; David Y Leger; Bertrand Liagre; Jean-Louis Beneytout; mohammed Hmamouchi
Citral inhibits cell proliferation and induces apoptosis and cell cycle arrest in MCF-7 cells.
Fundamental & clinical pharmacology 2009;23(5):549-56.
2009: W Chaouki; D Y Leger; Bertrand Liagre; Y Cherrah; Jean-Louis Beneytout; M Hmamouchi
Roots of Daphne gnidium L. inhibit cell proliferation and induce apoptosis in the human breast cancer cell line MCF-7.
Die Pharmazie 2009;64(8):542-6.
2009: Clementine Cailleteau; Bertrand Liagre; Jean-Louis Beneytout
A proteomic approach to the identification of molecular targets in subsequent apoptosis of HEL cells after diosgenin-induced megakaryocytic differentiation.
Journal of cellular biochemistry 2009;107(4):785-96.
2009: J Bertrand; Bertrand Liagre; G Bégaud-Grimaud; Marie-Odile Jauberteau; Jean-Louis Beneytout; P J P Cardot; Serge Battu
Analysis of relationship between cell cycle stage and apoptosis induction in K562 cells by sedimentation field-flow fractionation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(11-12):1155-61.
2008: C Cailleteau; Bertrand Liagre; Serge Battu; Chantal Jayat-Vignoles; Jean-Louis Beneytout
Increased cyclooxygenase-2 and thromboxane synthase expression is implicated in diosgenin-induced megakaryocytic differentiation in human erythroleukemia cells.
Analytical biochemistry 2008;380(1):26-34.
2008: J Bertrand; Bertrand Liagre; G Bégaud-Grimaud; Marie-Odile Jauberteau; P J P Cardot; Jean-Louis Beneytout; Serge Battu
Study of diosgenin-induced apoptosis kinetics in K562 cells by Sedimentation Field Flow Fractionation.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;869(1-2):75-83.
2007: Bertrand Liagre; Pascale Vergne-Salle; David LEGER; Jean-Louis Beneytout
Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and tigogenin is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2.
International journal of molecular medicine 2007;20(4):451-60.
2007: David Yannick Léger; Serge Battu; Bertrand Liagre; P J P Cardot; Jean-Louis Beneytout
Sedimentation field flow fractionation to study human erythroleukemia cell megakaryocytic differentiation after short period diosgenin induction.
Journal of chromatography. A 2007;1157(1-2):309-20.
2007: Bertrand Liagre; David LEGER; Pascale Vergne-Salle; Jean-Louis Beneytout
MAP kinase subtypes and Akt regulate diosgenin-induced apoptosis of rheumatoid synovial cells in association with COX-2 expression and prostanoid production.
International journal of molecular medicine 2007;19(1):113-22.
2006: David LEGER; Bertrand Liagre; Jean-Louis Beneytout
Low dose leflunomide activates PI3K/Akt signalling in erythroleukemia cells and reduces apoptosis induced by anticancer agents.
Apoptosis : an international journal on programmed cell death 2006;11(10):1747-60.
2006: G Bégaud-Grimaud; Serge Battu; Bertrand Liagre; David Yannick Léger; Jean-Louis Beneytout; P J P Cardot
Pre-apoptotic sub-population cell sorting from diosgenin apoptosis induced 1547 cells by Sedimentation Field-Flow Fractionation. The effect of channel thickness on sorting performance.
Journal of chromatography. A 2006;1128(1-2):194-202.
2006: David Yannick Léger; Serge Battu; Bertrand Liagre; Jean-Louis Beneytout; P J P Cardot
Megakaryocyte cell sorting from diosgenin-differentiated human erythroleukemia cells by sedimentation field-flow fractionation.
Analytical biochemistry 2006;355(1):19-28.
2006: David LEGER; Bertrand Liagre; Jean-Louis Beneytout
Role of MAPKs and NF-kappaB in diosgenin-induced megakaryocytic differentiation and subsequent apoptosis in HEL cells.
International journal of oncology 2006;28(1):201-7.
2005: Bertrand Liagre; Julian Bertrand; David LEGER; Jean-Louis Beneytout
Diosgenin, a plant steroid, induces apoptosis in COX-2 deficient K562 cells with activation of the p38 MAP kinase signalling and inhibition of NF-kappaB binding.
International journal of molecular medicine 2005;16(6):1095-101.
2005: Pascale Vergne-Salle; David Yannick Léger; Philippe Bertin; Richard Trèves; Jean-Louis Beneytout; Bertrand Liagre
Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
Cytokine 2005;31(5):335-48.
2005: Patrick Trouillas; Cécile Corbière; Bertrand Liagre; Jean-Luc Duroux; Jean-Louis Beneytout
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin.
Bioorganic & medicinal chemistry 2005;13(4):1141-9.
2004: David Yannick Léger; Bertrand Liagre; P J P Cardot; Jean-Louis Beneytout; Serge Battu
Diosgenin dose-dependent apoptosis and differentiation induction in human erythroleukemia cell line and sedimentation field-flow fractionation monitoring.
Analytical biochemistry 2004;335(2):267-78.
2004: Cécile Corbière; Serge Battu; Bertrand Liagre; P J P Cardot; Jean-Louis Beneytout
SdFFF monitoring of cellular apoptosis induction by diosgenin and different inducers in the human 1547 osteosarcoma cell line.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;808(2):255-62.
2004: David LEGER; Bertrand Liagre; Cécile Corbière; Jeanne Cook-Moreau; Jean-Louis Beneytout
Diosgenin induces cell cycle arrest and apoptosis in HEL cells with increase in intracellular calcium level, activation of cPLA2 and COX-2 overexpression.
International journal of oncology 2004;25(3):555-62.
2004: Cecile Corbiere; Bertrand Liagre; Faraj Terro; Jean-Louis Beneytout
Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells.
Cell research 2004;14(3):188-96.
2004: Bertrand Liagre; Pascale Vergne-Salle; Cecile Corbiere; Jean Louis Charissoux; Jean-Louis Beneytout
Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression.
Arthritis research & therapy 2004;6(4):R373-83.
2003: Pierre-Olivier Harmand; RAPHAEL EMMANUEL DUVAL; Bertrand Liagre; Chantal Jayat-Vignoles; Jean-Louis Beneytout; Christiane Delage; Alain Simon
Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells.
International journal of oncology 2003;23(1):105-12.
2003: Laurent Grossin; Christel Cournil-Henrionnet; Lluis M Mir; Bertrand Liagre; Dominique Dumas; Stéphanie Etienne; Corinne Guingamp; Patrick Netter; Pierre Gillet
Direct gene transfer into rat articular cartilage by in vivo electroporation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):829-35.
2003: Cecile Corbiere; Bertrand Liagre; Arnaud Bianchi; Karim Bordji; Michel Dauça; Patrick Netter; Jean-Louis Beneytout
Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells.
International journal of oncology 2003;22(4):899-905.
2002: Bertrand Liagre; S Moalic; Pascale Vergne; Jean Louis Charissoux; D Bernache-Assollant; Jean-Louis Beneytout
Effects of alumina and zirconium dioxide particles on arachidonic acid metabolism and proinflammatory interleukin production in osteoarthritis and rheumatoid synovial cells.
The Journal of bone and joint surgery. British volume 2002;84(6):920-30.
2002: Sandra Moalic-Juge; Bertrand Liagre; RAPHAEL EMMANUEL DUVAL; Cecile Corbiere; Arnaud Bianchi; Karim Bordji; Claudine Bosgiraud; Jean-Louis Beneytout
The anti-apoptotic property of NS-398 at high dose can be mediated in part through NF-kappaB activation, hsp70 induction and a decrease in caspase-3 activity in human osteosarcoma cells.
International journal of oncology 2002;20(6):1255-62.
2001: S Moalic; Bertrand Liagre; Cécile Corbière; Arnaud Bianchi; Michel Dauça; Karim Bordji; Jean-Louis Beneytout
A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells.
FEBS letters 2001;506(3):225-30.
2001: JC Le Bail; Bertrand Liagre; Pascale Vergne; Philippe Bertin; Jean-Louis Beneytout; G Habrioux
Aromatase in synovial cells from postmenopausal women.
Steroids 2001;66(10):749-57.
2001: Sandrine Boyault; Marie-Agnès Simonin; Arnaud Bianchi; E Compe; Bertrand Liagre; Didier Mainard; Philippe Bécuwe; Michel Dauça; Patrick Netter; Bernard Terlain; Karim Bordji
15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways.
FEBS letters 2001;501(1):24-30.
2001: S Moalic; Bertrand Liagre; JC Le Bail; Jean-Louis Beneytout
Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor.
International journal of oncology 2001;18(3):533-40.
2000: S Moalic; Bertrand Liagre; F Labrousse; Jean-Louis Beneytout
Enhanced apoptosis in retrovirally transfected osteosarcoma cells after exposure to sodium butyrate.
International journal of oncology 2000;16(4):695-700.
1999: Bertrand Liagre; Pascale Vergne; Michel Rigaud; Jean-Louis Beneytout
Arachidonate 15-lipoxygenase of reticulocyte-type in human rheumatoid arthritis type B synoviocytes and modulation of its activity by proinflammatory cytokines.
The Journal of rheumatology 1999;26(5):1044-51.
1998: Pascale Vergne; Bertrand Liagre; Philippe Bertin; Jeanne Cook-Moreau; Richard Treves; Jean-Louis Beneytout; Michel Rigaud
Methotrexate and cyclooxygenase metabolism in cultured human rheumatoid synoviocytes.
The Journal of rheumatology 1998;25(3):433-40.
1997: Bertrand Liagre; Pascale Vergne; Michel Rigaud; Jean-Louis Beneytout
Expression of arachidonate platelet-type 12-lipoxygenase in human rheumatoid arthritis type B synoviocytes.
FEBS letters 1997;414(1):159-64.
1997: Bertrand Liagre; Jean Louis Charissoux; MJ Leboutet; D Bernache-Assollant; Jean-Louis Beneytout
Interactions of hydroxyapatite and fluorapatite particles on human osteoarthritis type B synoviocytes: effects on interleukin-1 alpha levels and lipoxygenase pathways.
Journal of biomedical materials research 1997;38(3):243-56.
1995: C Nappez; Bertrand Liagre; Jean-Louis Beneytout
Changes in lipoxygenase activities in human erythroleukemia (HEL) cells during diosgenin-induced differentiation.
Cancer letters 1995;96(1):133-40.