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James Adelstein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Singh Amarjit; Yang Yongliang; Adelstein S James; Kassis Amin I
Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution.
Balagurumoorthy Pichumani; Wang Ketai; Adelstein S James; Kassis Amin I
DNA double-strand breaks induced by decay of (123)I-labeled Hoechst 33342: role of DNA topology.
Howell R W; Martin R F; Nikjoo H; Pomplun E; Terrissol M; Watanable R; Yasui L; Kassis Amin I; Adelstein S James
Meeting overview.

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All Publications

2008: Singh Amarjit; Yang Yongliang; Adelstein S James; Kassis Amin I
Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution.
International journal of radiation biology 2008;84(12):1001-10.
2008: Balagurumoorthy Pichumani; Wang Ketai; Adelstein S James; Kassis Amin I
DNA double-strand breaks induced by decay of (123)I-labeled Hoechst 33342: role of DNA topology.
International journal of radiation biology 2008;84(12):976-83.
2008: Howell R W; Martin R F; Nikjoo H; Pomplun E; Terrissol M; Watanable R; Yasui L; Kassis Amin I; Adelstein S James
Meeting overview.
International journal of radiation biology 2008;84(12):957-8.
2008: Balagurumoorthy Pichumani; Adelstein S James; Kassis Amin I
Method to eliminate linear DNA from mixture containing nicked circular, supercoiled, and linear plasmid DNA.
Analytical biochemistry 2008;381(1):172-4.
2008: Wang Ketai; Adelstein S James; Kassis Amin I
DMSO increases radioiodination yield of radiopharmaceuticals.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2008;66(1):50-9.
2008: Yang Yongliang; Pospisil Pavel; Iyer Lakshmanan K; Adelstein S James; Kassis Amin I
Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer.
PloS one 2008;3(11):e3661.
2008: Kassis Amin I; Korideck Houari; Wang Ketai; Pospisil Pavel; Adelstein S James
Novel prodrugs for targeting diagnostic and therapeutic radionuclides to solid tumors.
Molecules (Basel, Switzerland) 2008;13(2):391-404.
2007: Singh Amarjit; Chen Kai; Adelstein S James; Kassis Amin I
Synthesis of coumarin-polyamine-based molecular probe for the detection of hydroxyl radicals generated by gamma radiation.
Radiation research 2007;168(2):233-42.
2007: Wang Ketai; Kirichian Agop M; Aowad Ayman F Al; Adelstein S James; Kassis Amin I
Evaluation of chemical, physical, and biologic properties of tumor-targeting radioiodinated quinazolinone derivative.
Bioconjugate chemistry 2007;18(3):754-64.
2007: Pospisil Pavel; Wang Ketai; Al Aowad Ayman F; Iyer Lakshmanan K; Adelstein S James; Kassis Amin I
Computational modeling and experimental evaluation of a novel prodrug for targeting the extracellular space of prostate tumors.
Cancer research 2007;67(5):2197-205.
2007: Chen Kai; Aowad Ayman F Al; Adelstein S James; Kassis Amin I
Molecular-docking-guided design, synthesis, and biologic evaluation of radioiodinated quinazolinone prodrugs.
Journal of medicinal chemistry 2007;50(4):663-73.
2006: Chen Kai; Wang Ketai; Kirichian Agop M; Al Aowad Ayman F; Iyer Lakshmanan K; Adelstein S James; Kassis Amin I
In silico design, synthesis, and biological evaluation of radioiodinated quinazolinone derivatives for alkaline phosphatase-mediated cancer diagnosis and therapy.
Molecular cancer therapeutics 2006;5(12):3001-13.
2006: Urashima Tetsuro; Nagasawa Hatsumi; Wang Ketai; Adelstein S James; Little John B; Kassis Amin I
Induction of apoptosis in human tumor cells after exposure to Auger electrons: comparison with gamma-ray exposure.
Nuclear medicine and biology 2006;33(8):1055-63.
2006: Balagurumoorthy Pichumani; Chen Kai; Bash Ralph C; Adelstein S James; Kassis Amin I
Mechanisms underlying production of double-strand breaks in plasmid DNA after decay of 125I-Hoechst.
Radiation research 2006;166(2):333-44.
2006: Kishikawa Hiroko; Wang Ketai; Adelstein S James; Kassis Amin I
Inhibitory and stimulatory bystander effects are differentially induced by Iodine-125 and Iodine-123.
Radiation research 2006;165(6):688-94.
2006: Pospisil Pavel; Iyer Lakshmanan K; Adelstein S James; Kassis Amin I
A combined approach to data mining of textual and structured data to identify cancer-related targets.
BMC bioinformatics 2006;7():354.
2005: Semnani Elham Safaie; Wang Ketai; Adelstein S James; Kassis Amin I
5-[123I/125I]iodo-2'-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(5):800-6.
2005: Kassis Amin I; Adelstein S James
Radiobiologic principles in radionuclide therapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46 Suppl 1():4S-12S.
2004: Kassis Amin I; Kirichian Agop M; Wang Ketai; Semnani Elham Safaie; Adelstein S James
Therapeutic potential of 5-[125I]iodo-2'-deoxyuridine and methotrexate in the treatment of advanced neoplastic meningitis.
International journal of radiation biology 2004;80(11-12):941-6.
2004: Chen Kai; Adelstein S James; Kassis Amin I
Molecular simulation of ligand-binding with DNA: implications for 125I-labeled pharmaceutical design.
International journal of radiation biology 2004;80(11-12):921-6.
2004: Urashima Tetsuro; Wang Ketai; Adelstein S James; Kassis Amin I
Activation of diverse pathways to apoptosis by (125)IdUrd and gamma-photon exposure.
International journal of radiation biology 2004;80(11-12):867-74.
2003: Bodei Lisa; Kassis Amin I; Adelstein S James; Mariani Giuliano
Radionuclide therapy with iodine-125 and other auger-electron-emitting radionuclides: experimental models and clinical applications.
Cancer biotherapy & radiopharmaceuticals 2003;18(6):861-77.
2003: Adelstein S James; Kassis Amin I; Bodei Lisa; Mariani Giuliano
Radiotoxicity of iodine-125 and other auger-electron-emitting radionuclides: background to therapy.
Cancer biotherapy & radiopharmaceuticals 2003;18(3):301-16.
2002: Xue Lanny Y; Butler Nicholas J; Makrigiorgos G Mike; Adelstein S James; Kassis Amin I
Bystander effect produced by radiolabeled tumor cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13765-70.
2002: Ho Nan-hui; Harapanhalli Ravi S; Dahman Bassam A; Chen Kai; Wang Ketai; Adelstein S James; Kassis Amin I
Synthesis and biologic evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated insolubilization therapy.
Bioconjugate chemistry 2002;13(2):357-64.
2001: Adelstein S J
Robley Evans and what physics can do for medicine.
Cancer biotherapy & radiopharmaceuticals 2001;16(3):179-85.
2001: Walicka M A; Adelstein S J; Kassis A I
Chemical modification of 5-[125I]iodo-2'-deoxyuridine toxicity in mammalian cells in vitro.
International journal of radiation biology 2001;77(5):625-30.
2001: Adelstein S J
The 2000 NCRP Lauriston S. Taylor lecture--administered radioactivity: unde venimus quoque imus. National Council on Radiation Protection and Measurements.
Health physics 2001;80(4):317-24.
2000: Walicka M A; Ding Y; Adelstein S J; Kassis A I
Morphological transformation of C3H 10T1/2 cells by 99mTc-cardiolite.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(9):1545-51.
2000: Mariani G; Bodei L; Adelstein S J; Kassis A I
Emerging roles for radiometabolic therapy of tumors based on auger electron emission.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(9):1519-21.
2000: Walicka M A; Ding Y; Adelstein S J; Kassiss A I
Toxicity of DNA-incorporated iodine-125: quantifying the direct and indirect effects.
Radiation research 2000;154(3):326-30.
2000: Kassis A I; Dahman B A; Adelstein S J
In vivo therapy of neoplastic meningitis with methotrexate and 5.
Acta oncologica (Stockholm, Sweden) 2000;39(6):731-7.
2000: Kassis A I; Walicka M A; Adelstein S J
Double-strand break yield following 125I decay--effects of DNA conformation.
Acta oncologica (Stockholm, Sweden) 2000;39(6):721-6.
1999: Walicka M A; Ding Y; Roy A M; Harapanhalli R S; Adelstein S J; Kassis A I
Cytotoxicity of [125I]iodoHoechst 33342: contribution of scavengeable effects.
International journal of radiation biology 1999;75(12):1579-87.
1999: Kassis A I; Harapanhalli R S; Adelstein S J
Strand breaks in plasmid DNA after positional changes of Auger electron-emitting iodine-125: direct compared to indirect effects.
Radiation research 1999;152(5):530-8.
1999: Adelstein S J
Radionuclide exposure during pregnancy: "60 Minutes" film.
Teratology 1999;59(4):301.
1999: Adelstein S J
Administered radionuclides in pregnancy.
Teratology 1999;59(4):236-9.
1999: Kassis A I; Harapanhalli R S; Adelstein S J
Comparison of strand breaks in plasmid DNA after positional changes of Auger electron-emitting iodine-125.
Radiation research 1999;151(2):167-76.
1998: Walicka M A; Vaidyanathan G; Zalutsky M R; Adelstein S J; Kassis A I
Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211.
Radiation research 1998;150(3):263-8.
1998: Kassis A I; Wen P Y; Van den Abbeele A D; Baranowska-Kortylewicz J; Makrigiorgos G M; Metz K R; Matalka K Z; Cook C U; Sahu S K; Black P M; Adelstein S J
5-[125I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(7):1148-54.
1998: Harapanhalli R S; Roy A M; Adelstein S J; Kassis A I
[125I/127I/131I]Iodorhodamine: synthesis, cellular localization, and biodistribution in athymic mice bearing human tumor xenografts and comparison with [99mTc]hexakis(2-methoxyisobutylisonitrile).
Journal of medicinal chemistry 1998;41(12):2111-7.
1998: Harapanhalli R S; Matalka K Z; Jones P L; Mahmood A; Adelstein S J; Kassis A I
Lysine-directed conjugation of ethidium homodimer to B72.3 antibody: retention of immunoreactivity but altered tumor targeting.
Nuclear medicine and biology 1998;25(3):267-78.
1998: Walicka M A; Adelstein S J; Kassis A I
Indirect mechanisms contribute to biological effects produced by decay of DNA-incorporated iodine-125 in mammalian cells in vitro: clonogenic survival.
Radiation research 1998;149(2):142-6.
1998: Walicka M A; Adelstein S J; Kassis A I
Indirect mechanisms contribute to biological effects produced by decay of DNA-incorporated iodine-125 in mammalian cells in vitro: double-strand breaks.
Radiation research 1998;149(2):134-41.
1997: Sahu S K; Kortylewicz Z P; Baranowska-Kortylewicz J; Taube R A; Adelstein S J; Kassis A I
Strand breaks after the decay of iodine-125 in proximity to plasmid pBR322 DNA.
Radiation research 1997;147(4):401-8.
1997: Sahu S K; Wen P Y; Foulon C F; Nagel J S; Black P M; Adelstein S J; Kassis A I
Intrathecal 5-[125I]iodo-2'-deoxyuridine in a rat model of leptomeningeal metastases.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(3):386-90.
1996: Harapanhalli R S; McLaughlin L W; Howell R W; Rao D V; Adelstein S J; Kassis A I
[125I/127I]iodoHoechst 33342: synthesis, DNA binding, and biodistribution.
Journal of medicinal chemistry 1996;39(24):4804-9.
1996: Kassis A I; Adelstein S J; Mariani G
Radiolabeled nucleoside analogs in cancer diagnosis and therapy.
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 1996;40(3):301-19.
1996: Kassis A I; Tumeh S S; Wen P Y; Baranowska-Kortylewicz J; Van den Abbeele A D; Zimmerman R E; Carvalho P A; Garada B M; DeSisto W C; Bailey N O; Castronovo F P; Mariani G; Black P M; Adelstein S J
Intratumoral administration of 5-[123I]iodo-2'-deoxyuridine in a patient with a brain tumor.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(4 Suppl):19S-22S.
1996: Kassis A I; Adelstein S J
Preclinical animal studies with radioiododeoxyuridine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(4 Suppl):10S-12S.
1996: Foulon C F; Adelstein S J; Kassis A I
Kit formulation for the preparation of radiolabeled iododeoxyuridine by demetallation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(4 Suppl):1S-3S.
1996: Kassis A I; Jones P L; Matalka K Z; Adelstein S J
Antibody-dependent signal amplification in tumor xenografts after pretreatment with biotinylated monoclonal antibody and avidin or streptavidin.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):343-52.
1996: Van den Abbeele A D; Tutrone R F; Berman R M; Baranowska-Kortylewicz J; Barclay P D; Richie J P; Adelstein S J; Kassis A I
Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):315-20.
1996: Kassis A I; Adelstein S J
5-[125]iodo-2'-deoxyuridine in the radiotherapy of solid CNS tumors in rats.
Acta oncologica (Stockholm, Sweden) 1996;35(7):935-9.
1996: Adelstein S J; Kassis A I
Strand breaks in plasmid DNA following positional changes of Auger-electron-emitting radionuclides.
Acta oncologica (Stockholm, Sweden) 1996;35(7):797-801.
1995: Foulon C F; Zhang Y Z; Adelstein S J; Kassis A I
Instantaneous preparation of radiolabeled 5-iodo-2'-deoxyuridine.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1995;46(10):1039-46.
1995: Sahu S K; Kassis A I; Makrigiorgos G M; Baranowska-Kortylewicz J; Adelstein S J
The effects of indium-111 decay on pBR322 DNA.
Radiation research 1995;141(2):193-8.
1993: Adelstein S J
Merrill C. Sosman Lecture. The Auger process: a therapeutic promise?
AJR. American journal of roentgenology 1993;160(4):707-13.
1992: Makrigiorgos G M; Berman R M; Baranowska-Kortylewicz J; Bump E; Humm J L; Adelstein S J; Kassis A I
DNA damage produced in V79 cells by DNA-incorporated iodine-123: a comparison with iodine-125.
Radiation research 1992;129(3):309-14.
1991: Baranowska-Kortylewicz J; Makrigiorgos G M; Van den Abbeele A D; Berman R M; Adelstein S J; Kassis A I
5-[123I]iodo-2'-deoxyuridine in the radiotherapy of an early ascites tumor model.
International journal of radiation oncology, biology, physics 1991;21(6):1541-51.
1991: Kassis A I; Guptill W E; Taube R A; Adelstein S J
Radiotoxicity of 5-[125I]iodo-2'-deoxyuridine in mammalian cells following treatment with 5-fluoro-2'-deoxyuridine.
Journal of nuclear biology and medicine (Turin, Italy : 1991) 1991;35(3):167-73.
1991: Mariani G; Ito S; Nayak R C; Baranowska-Kortylewicz J; Venkateshan C N; Van den Abbeele A D; Eisenbarth G S; Adelstein S J; Kassis A I
Capping and internalization of a monoclonal antibody-surface antigen complex: a possible mode of interaction of monoclonal antibodies and tumor cells.
Journal of nuclear biology and medicine (Turin, Italy : 1991) 1991;35(2):111-9.
1991: Van den Abbeele A D; Aaronson R A; Daher S; Taube R A; Adelstein S J; Kassis A I
Antigen-binding site protection during radiolabeling leads to a higher immunoreactive fraction.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(1):116-22.
1991: Adelstein S J; Kassis A I; Baranowska-Kortylewicz J; van den Abbeele A D; Mariani G; Ito S
Potential for tumor therapy with iodine-125 labeled immunoglobulins.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991;18(1):43-4.
1990: Makrigiorgos G M; Ito S; Baranowska-Kortylewicz J; Vinter D W; Iqbal A; Van den Abbeele A D; Adelstein S J; Kassis A I
Inhomogeneous deposition of radiopharmaceuticals at the cellular level: experimental evidence and dosimetric implications.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1990;31(8):1358-63.
1990: Kassis A I; Van den Abbeele A D; Wen P Y; Baranowska-Kortylewicz J; Aaronson R A; DeSisto W C; Lampson L A; Black P M; Adelstein S J
Specific uptake of the auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans.
Cancer research 1990;50(16):5199-203.
1990: Makrigiorgos G M; Adelstein S J; Kassis A I
Cellular radiation dosimetry and its implications for estimation of radiation risks. Illustrative results with technetium 99m-labeled microspheres and macroaggregates.
JAMA : the journal of the American Medical Association 1990;264(5):592-5.
1990: Whaley J M; Kassis A I; Kinsey B M; Adelstein S J; Little J B
Mutation induction by 125iodoacetylproflavine, a DNA-intercalating agent, in human cells.
International journal of radiation biology 1990;57(6):1087-103.
1990: van den Abbeele A D; Aaronson R A; Taube R A; Adelstein S J; Kassis A I
Preadsorption of radiolabeled monoclonal antibodies to liver and spleen tissues leads to higher tumor-to-normal-tissue ratios.
The Journal of nuclear medicine and allied sciences 1990;34(2):94-102.
1990: Baranowska-Kortylewicz J; Adelstein S J; Kassis A I
5-iodo-2'-deoxyuridine-protein conjugates: synthesis and enzymatic degradation.
Selective cancer therapeutics 1990;6(1):1-13.
1990: Kinsey B M; Fayad F; Venkateshan C N; Adelstein S J; Kassis A I
Synthesis and biological activity of the intercalating agent 3-acetamido-5-[123/125I]iodo-6-aminoacridine.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(3):341-6.
1990: Makrigiorgos G; Adelstein S J; Kassis A I
Auger electron emitters: insights gained from in vitro experiments.
Radiation and environmental biophysics 1990;29(2):75-91.
1989: Makrigiorgos G M; Adelstein S J; Kassis A I
Limitations of conventional internal dosimetry at the cellular level.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(11):1856-64.
1989: Kinsey B M; Van den Abbeele A D; Adelstein S J; Kassis A I
Absence of preferential uptake of [125I]iododihydrorhodamine 123 by four human tumor xenografts.
Cancer research 1989;49(21):5986-8.
1989: Makrigiorgos G M; Kassis A I; Baranowska-Kortylewicz J; McElvany K D; Welch M J; Sastry K S; Adelstein S J
Radiotoxicity of 5-[123I]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[125I]iodo-2'-deoxyuridine.
Radiation research 1989;118(3):532-44.
1989: Kassis A I; Fayad F; Kinsey B M; Sastry K S; Adelstein S J
Radiotoxicity of an 125I-labeled DNA intercalator in mammalian cells.
Radiation research 1989;118(2):283-94.
1989: Mariani G; Abbeele A D; Venkateshan C N; Kaldany A; Ito S; Adelstein S J; Kassis A I
Monoclonal antibody internalization by tumor cells: an experimental model for potential radioimmunotherapy applications.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1989;16(2):147-50.
1988: Van den Abbeele A D; Aaronson R A; Adelstein S J; Kassis A I
Does the in vitro testing of the immunoreactivity of an antibody reflect its in vivo behavior?
The Journal of nuclear medicine and allied sciences 1988;32(4):260-7.
1988: Macklis R M; Kinsey B M; Kassis A I; Ferrara J L; Atcher R W; Hines J J; Coleman C N; Adelstein S J; Burakoff S J
Radioimmunotherapy with alpha-particle-emitting immunoconjugates.
Science (New York, N.Y.) 1988;240(4855):1024-6.
1987: Kinsey B M; Kassis A I; Fayad F; Layne W W; Adelstein S J
Synthesis and biological studies of iodinated (127/125I) derivatives of rhodamine 123.
Journal of medicinal chemistry 1987;30(10):1757-61.
1987: Kassis A I; Fayad F; Kinsey B M; Sastry K S; Taube R A; Adelstein S J
Radiotoxicity of 125I in mammalian cells.
Radiation research 1987;111(2):305-18.
1987: Adelstein S J; Kassis A I
Radiobiologic implications of the microscopic distribution of energy from radionuclides.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1987;14(3):165-9.
1986: Milius R A; McLaughlin W H; Lambrecht R M; Wolf A P; Carroll J J; Adelstein S J; Bloomer W D
Organoastatine chemistry. Astatination via electrophilic destannylation.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1986;37(8):799-802.
1984: Bloomer W D; McLaughlin W H; Lambrecht R M; Atcher R W; Mirzadeh S; Madara J L; Milius R A; Zalutsky M R; Adelstein S J; Wolf A P
211At radiocolloid therapy: further observations and comparison with radiocolloids of 32P, 165Dy, and 90Y.
International journal of radiation oncology, biology, physics 1984;10(3):341-8.
1983: Kassis A I; Adelstein S J; Haydock C; Sastry K S
Thallium-201: an experimental and a theoretical radiobiological approach to dosimetry.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1983;24(12):1164-75.
1983: Bloomer W D; McLaughlin W H; Milius R A; Weichselbaum R R; Adelstein S J
Estrogen receptor-mediated cytotoxicity using iodine-125.
Journal of cellular biochemistry 1983;21(1):39-45.
1982: Kassis A I; Adelstein S J; Haydock C; Sastry K S; McElvany K D; Welch M J
Lethality of Auger electrons from the decay of bromine-77 in the DNA of mammalian cells.
Radiation research 1982;90(2):362-73.
1980: Kassis A I; Adelstein S J; Haydock C; Sastry K S
Radiotoxicity of 75Se and 35S: theory and application to a cellular model.
Radiation research 1980;84(3):407-25.

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