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Haihui Liao

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S J Brown; Caroline L Relton; Haihui Liao; Y Zhao; Aileen Sandilands; W H I McLean; H J Cordell; Nick J Reynolds
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.
Kaninika Basu; Colin N A Palmer; Brian J Lipworth; W H Irwin McLean; Ana Terron-Kwiatkowski; Yiwei Zhao; Haihui Liao; Frances J D Smith; A Mitra; Somnath Mukhopadhyay
Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults.
Sara J Brown; Aileen Sandilands; Yiwei Zhao; Haihui Liao; Caroline L Relton; Simon J Meggitt; Richard C Trembath; Jonathan N W N Barker; Nick J Reynolds; Heather J Cordell; W H Irwin McLean
Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema.

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2009: S J Brown; Caroline L Relton; Haihui Liao; Y Zhao; Aileen Sandilands; W H I McLean; H J Cordell; Nick J Reynolds
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.
The British journal of dermatology 2009;161(4):884-9.
2008: Kaninika Basu; Colin N A Palmer; Brian J Lipworth; W H Irwin McLean; Ana Terron-Kwiatkowski; Yiwei Zhao; Haihui Liao; Frances J D Smith; A Mitra; Somnath Mukhopadhyay
Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults.
Allergy 2008;63(9):1211-7.
2008: Sara J Brown; Aileen Sandilands; Yiwei Zhao; Haihui Liao; Caroline L Relton; Simon J Meggitt; Richard C Trembath; Jonathan N W N Barker; Nick J Reynolds; Heather J Cordell; W H Irwin McLean
Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema.
The Journal of investigative dermatology 2008;128(6):1591-4.
2008: Sara J Brown; Caroline L Relton; Haihui Liao; Yiwei Zhao; Aileen Sandilands; Ian J Wilson; John Burn; Nick J Reynolds; W H Irwin McLean; Heather J Cordell
Filaggrin null mutations and childhood atopic eczema: a population-based case-control study.
The Journal of allergy and clinical immunology 2008;121(4):940-46.e3.
2007: Haihui Liao; Jane M Sayers; Neil J Wilson; Alan D Irvine; Jemima E Mellerio; Eulalia Baselga; Susan J Bayliss; Vera Uliana; Michele Fimiani; E Birgitte Lane; W H Irwin McLean; Sancy A Leachman; Frances J D Smith
A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita.
Journal of dermatological science 2007;48(3):199-205.
2007: Haihui Liao; Alex J Waters; David R Goudie; David A Aitken; Gordon Graham; Frances J D Smith; Sue Lewis-Jones; W H Irwin McLean
Filaggrin mutations are genetic modifying factors exacerbating X-linked ichthyosis.
The Journal of investigative dermatology 2007;127(12):2795-8.
2007: Yiwei Zhao; Ana Terron-Kwiatkowski; Haihui Liao; Simon P Lee; Michael H Allen; Peter R Hull; Linda E Campbell; Richard C Trembath; Francesca Capon; Christopher E M Griffiths; David Burden; Ross McManus; Rosalind Hughes; Brian Kirby; Sarah F Rogers; Oliver Fitzgerald; David Kane; J N W N Barker; Colin N A Palmer; Alan D Irvine; W H Irwin McLean
Filaggrin null alleles are not associated with psoriasis.
The Journal of investigative dermatology 2007;127(8):1878-82.
2007: Colin N A Palmer; Tahmina Ismail; Simon P Lee; Ana Terron-Kwiatkowski; Yiwei Zhao; Haihui Liao; Frances J D Smith; W H Irwin McLean; Somnath Mukhopadhyay
Filaggrin null mutations are associated with increased asthma severity in children and young adults.
The Journal of allergy and clinical immunology 2007;120(1):64-8.
2007: Aileen Sandilands; Ana Terron-Kwiatkowski; Peter R Hull; Gráinne M O'Regan; Timothy H Clayton; Rosemarie M Watson; Thomas Carrick; Alan T Evans; Haihui Liao; Yiwei Zhao; Linda E Campbell; Matthias Schmuth; Robert Gruber; Andreas R Janecke; Peter M Elias; Maurice A M van Steensel; Ivo Nagtzaam; Michel van Geel; Peter M Steijlen; Colin S Munro; Daniel G Bradley; Colin N A Palmer; Frances J D Smith; W H Irwin McLean; Alan D Irvine
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
Nature genetics 2007;39(5):650-4.
2007: J N W N Barker; Colin N A Palmer; Yiwei Zhao; Haihui Liao; Peter R Hull; Simon P Lee; Michael H Allen; Simon J Meggitt; Nick J Reynolds; Richard C Trembath; W H Irwin McLean
Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood.
The Journal of investigative dermatology 2007;127(3):564-7.
2007: Toshifumi Nomura; Aileen Sandilands; Masashi Akiyama; Haihui Liao; Alan T Evans; Kaori Sakai; Mitsuhito Ota; Hisashi Sugiura; Kazuo Yamamoto; Hiroshi Sato; Colin N A Palmer; Frances J D Smith; W H Irwin McLean; Hiroshi Shimizu
Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis.
The Journal of allergy and clinical immunology 2007;119(2):434-40.
2007: Haihui Liao; Yiwei Zhao; David U Baty; John A McGrath; Jemima E Mellerio; W H Irwin McLean
A heterozygous frameshift mutation in the V1 domain of keratin 5 in a family with Dowling-Degos disease.
The Journal of investigative dermatology 2007;127(2):298-300.
2006: Aileen Sandilands; Gráinne M O'Regan; Haihui Liao; Yiwei Zhao; Ana Terron-Kwiatkowski; Rosemarie M Watson; Andrew J Cassidy; David R Goudie; Frances J D Smith; W H Irwin McLean; Alan D Irvine
Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis.
The Journal of investigative dermatology 2006;126(8):1770-5.
2006: Colin N A Palmer; Alan D Irvine; Ana Terron-Kwiatkowski; Yiwei Zhao; Haihui Liao; Simon P Lee; David R Goudie; Aileen Sandilands; Linda E Campbell; Frances J D Smith; Gráinne M O'Regan; Rosemarie M Watson; Joanne E Cecil; Sherri J Bale; John G Compton; John J DiGiovanna; Philip Fleckman; Sue Lewis-Jones; Gehan Arseculeratne; Ann Sergeant; Colin S Munro; Brahim El Houate; Ken McElreavey; Liselotte B Halkjaer; Hans Bisgaard; Somnath Mukhopadhyay; W H Irwin McLean
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.
Nature genetics 2006;38(4):441-6.
2006: Frances J D Smith; Alan D Irvine; Ana Terron-Kwiatkowski; Aileen Sandilands; Linda E Campbell; Yiwei Zhao; Haihui Liao; Alan T Evans; David R Goudie; Sue Lewis-Jones; Gehan Arseculeratne; Colin S Munro; Ann Sergeant; Gráinne M O'Regan; Sherri J Bale; John G Compton; John J DiGiovanna; Richard B Presland; Philip Fleckman; W H Irwin McLean
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.
Nature genetics 2006;38(3):337-42.
2005: Frances J D Smith; Haihui Liao; Andrew J Cassidy; Arlene Stewart; Kevin J Hamill; Pamela Wood; Iris Joval; Maurice A M van Steensel; Erik Björck; Faith Callif-Daley; Gerald Pals; Paul Collins; Sancy A Leachman; Colin S Munro; W H Irwin McLean
The genetic basis of pachyonychia congenita.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2005;10(1):21-30.