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Emmanuelle Liaudet-Coopman

Research Profile

Chemicals & Drugs

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Mouse

Disorders

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Publications

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Valérie Laurent-Matha; Fabien Lecaille; Magnus Abrahamson; Danielle Derocq; Magali Gary-Bobo; Robert E Hollingsworth; Pitter F Huesgen; Gilles Lalmanach; Olivier Masson; Guillaume Meurice; Cédric Oréar; Christopher M Overall; Christine Prébois; Bertrand Rebière; Emmanuelle Liaudet-Coopman
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.
Danielle Derocq; Valérie Laurent-Matha; Sophie Pattingre; Christine Prébois; G K Smith; Mélanie Beaujouin; Emmanuelle Liaudet-Coopman
Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.
Olivier Masson; Christine Prébois; Danielle Derocq; Aline Meulle; Cédric Dray; Danièle Daviaud; Didier Quilliot; Philippe Valet; Catherine Muller; Emmanuelle Liaudet-Coopman
Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.

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All Publications

2012: Valérie Laurent-Matha; Fabien Lecaille; Magnus Abrahamson; Danielle Derocq; Magali Gary-Bobo; Robert E Hollingsworth; Pitter F Huesgen; Gilles Lalmanach; Olivier Masson; Guillaume Meurice; Cédric Oréar; Christopher M Overall; Christine Prébois; Bertrand Rebière; Emmanuelle Liaudet-Coopman
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(12):5172-81.
2012: Danielle Derocq; Valérie Laurent-Matha; Sophie Pattingre; Christine Prébois; G K Smith; Mélanie Beaujouin; Emmanuelle Liaudet-Coopman
Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.
Oncogene 2012;31(26):3202-12.
2011: Olivier Masson; Christine Prébois; Danielle Derocq; Aline Meulle; Cédric Dray; Danièle Daviaud; Didier Quilliot; Philippe Valet; Catherine Muller; Emmanuelle Liaudet-Coopman
Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.
PloS one 2011;6(2):e16452.
2010: Olivier Masson; Anne-Sophie Bach; Danielle Derocq; Christine Prébois; Valérie Laurent-Matha; Sophie Pattingre; Emmanuelle Liaudet-Coopman
Pathophysiological functions of cathepsin D: Targeting its catalytic activity versus its protein binding activity?
Biochimie 2010;92(11):1635-43.
2010: Mélanie Beaujouin; Christine Prébois; Danielle Derocq; Valérie Laurent-Matha; Olivier Masson; Sophie Pattingre; Peter Coopman; Nadir Bettache; Jami Grossfield; Robert E Hollingsworth; Hongyu Zhang; Zemin Yao; Bradley T Hyman; Peter van der Geer; Gary K Smith; Emmanuelle Liaudet-Coopman
Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.
Journal of cell science 2010;123(Pt 19):3336-46.
2009: Maria Berndtsson; Melanie Beaujouin; Linda Rickardson; Aleksandra Mandic Havelka; Rolf Larsson; Jacob Westman; Emmanuelle Liaudet-Coopman; Stig Linder
Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system.
International journal of cancer. Journal international du cancer 2009;124(6):1463-9.
2009: Olivier Masson; Carine Chavey; Cédric Dray; Aline Meulle; Danièle Daviaud; Didier Quilliot; Catherine Muller; Philippe Valet; Emmanuelle Liaudet-Coopman
LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.
PloS one 2009;4(10):e7422.
2008: Melanie Beaujouin; Emmanuelle Liaudet-Coopman
Cathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity.
Advances in experimental medicine and biology 2008;617():453-61.
2006: Emmanuelle Liaudet-Coopman; Mélanie Beaujouin; Danielle Derocq; Marcel Garcia; Murielle Glondu-Lassis; Valérie Laurent-Matha; Christine Prébois; Henri Rochefort; Françoise Vignon
Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis.
Cancer letters 2006;237(2):167-79.
2006: Mélanie Beaujouin; Stephen Baghdiguian; Murielle Glondu-Lassis; Guy Berchem; Emmanuelle Liaudet-Coopman
Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity.
Oncogene 2006;25(13):1967-73.
2006: Valérie Laurent-Matha; Danielle Derocq; Christine Prébois; Nobuhiko Katunuma; Emmanuelle Liaudet-Coopman
Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B.
Journal of biochemistry 2006;139(3):363-71.
2005: Valérie Laurent-Matha; Sharon Maruani-Herrmann; Christine Prébois; Mélanie Beaujouin; Murielle Glondu; Agnès Noël; Marie-Luz Alvarez-Gonzalez; Silvia Blacher; Peter J Coopman; Stephen Baghdiguian; Christine Gilles; Jadranka Loncarek; Gilles Freiss; Françoise Vignon; Emmanuelle Liaudet-Coopman
Catalytically inactive human cathepsin D triggers fibroblast invasive growth.
The Journal of cell biology 2005;168(3):489-99.
2002: Guy Berchem; Murielle Glondu; Michel Gleizes; Jean-Paul Brouillet; Françoise Vignon; Marcel Garcia; Emmanuelle Liaudet-Coopman
Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis.
Oncogene 2002;21(38):5951-5.
2002: Murielle Glondu; Emmanuelle Liaudet-Coopman; Danielle Derocq; Nadine Platet; Henri Rochefort; Marcel Garcia
Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.
Oncogene 2002;21(33):5127-34.
2001: Murielle Glondu; Peter J Coopman; Valérie Laurent-Matha; Marcel Garcia; Henri Rochefort; Emmanuelle Liaudet-Coopman
A mutated cathepsin-D devoid of its catalytic activity stimulates the growth of cancer cells.
Oncogene 2001;20(47):6920-9.
1999: Henri Rochefort; Emmanuelle Liaudet-Coopman
Cathepsin D in cancer metastasis: a protease and a ligand.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1999;107(1):86-95.