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Kai Licha

Research Profile

Chemicals & Drugs

Living Beings

Procedures

Occupations

Optics and Photonics

Genes & Molecular Sequences

Molecular Structure

Concepts & Ideas

Magnetic Resonance Imaging

Phenomena

Fluorescence

Disorders

Experimental Arthritis

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Publications

TOP 3
Timm Heek; Andreas Herrmann; Kai Licha; Jörg Nikolaus; Roland Schwarzer; Pia Welker; Carlo Fasting; Rainer Haag
An amphiphilic perylene imido diester for selective cellular imaging.
Stefania Biffi; Berislav Bosnjak; Simeone Dal Monego; Christian Dullin; Michelle M Epstein; Chiara Garrovo; Kai Licha; Pia Welker; Frauke Alves
Dendritic polyglycerolsulfate near infrared fluorescent (NIRF) dye conjugate for non-invasively monitoring of inflammation in an allergic asthma mouse model.
Jochen Müller; Andreas Wunder; Kai Licha
Optical imaging.

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All Publications

2013: Timm Heek; Andreas Herrmann; Kai Licha; Jörg Nikolaus; Roland Schwarzer; Pia Welker; Carlo Fasting; Rainer Haag
An amphiphilic perylene imido diester for selective cellular imaging.
Bioconjugate chemistry 2013;24(2):153-8.
2013: Stefania Biffi; Berislav Bosnjak; Simeone Dal Monego; Christian Dullin; Michelle M Epstein; Chiara Garrovo; Kai Licha; Pia Welker; Frauke Alves
Dendritic polyglycerolsulfate near infrared fluorescent (NIRF) dye conjugate for non-invasively monitoring of inflammation in an allergic asthma mouse model.
PloS one 2013;8(2):e57150.
2013: Jochen Müller; Andreas Wunder; Kai Licha
Optical imaging.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2013;187():221-46.
2012: Ines Gemeinhardt; Ole Gemeinhardt; Kai Licha; Rainer Macdonald; Diethard Petzelt; Dorothee Puls; Michael Schirner; Beatrix Schnorr; Matthias Taupitz; Susanne Wagner; Bernd Ebert; Jörg Schnorr
Near-infrared fluorescence imaging of experimentally collagen-induced arthritis in rats using the nonspecific dye tetrasulfocyanine in comparison with gadolinium-based contrast-enhanced magnetic resonance imaging, histology, and clinical score.
Journal of biomedical optics 2012;17(10):106008.
2011: Bernd Ebert; Björn Riefke; U Sukowski; Kai Licha
Cyanine dyes as contrast agents for near-infrared imaging in vivo: acute tolerance, pharmacokinetics, and fluorescence imaging.
Journal of biomedical optics 2011;16(6):066003.
2011: Marcelo Calderón; Pia Welker; Kai Licha; Iduna Fichtner; Ralph Graeser; Rainer Haag; Felix Kratz
Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell.
Journal of controlled release : official journal of the Controlled Release Society 2011;151(3):295-301.
2011: Stephanie Reichert; Pia Welker; Marcelo Calderón; Jayant Khandare; Dorothea Mangoldt; Kai Licha; Rajesh K Kainthan; Donald E Brooks; Rainer Haag
Size-dependant cellular uptake of dendritic polyglycerol.
Small (Weinheim an der Bergstrasse, Germany) 2011;7(6):820-9.
2010: Marcelo Calderón; Pia Welker; Kai Licha; Ralph Graeser; Felix Kratz; Rainer Haag
Development of efficient macromolecular prodrugs derived from dendritic polyglycerol.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e24-5.
2010: Jens Dernedde; Alexandra Rausch; Marie Weinhart; Sven Enders; Rudolf Tauber; Kai Licha; Michael Schirner; Ulrich Zügel; Arne von Bonin; Rainer Haag
Dendritic polyglycerol sulfates as multivalent inhibitors of inflammation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19679-84.
2010: Jayant Khandare; Andreas Mohr; Marcelo Calderón; Pia Welker; Kai Licha; Rainer Haag
Structure-biocompatibility relationship of dendritic polyglycerol derivatives.
Biomaterials 2010;31(15):4268-77.
2009: Sonja Vollmer; Axel Vater; Kai Licha; Ines Gemeinhardt; Ole Gemeinhardt; Jan Voigt; Bernd Ebert; Jörg Schnorr; Matthias Taupitz; Rainer Macdonald; Michael Schirner
Extra domain B fibronectin as a target for near-infrared fluorescence imaging of rheumatoid arthritis affected joints in vivo.
Molecular imaging 2009;8(6):330-40.
2009: Jan Klohs; Jens Steinbrink; Riad Bourayou; Susanne Mueller; Ryan Cordell; Kai Licha; Michael Schirner; Ulrich Dirnagl; Ute Lindauer; Andreas Wunder
Near-infrared fluorescence imaging with fluorescently labeled albumin: a novel method for non-invasive optical imaging of blood-brain barrier impairment after focal cerebral ischemia in mice.
Journal of neuroscience methods 2009;180(1):126-32.
2009: Shangjie Xu; Ying Luo; Ralph Graeser; André Warnecke; Felix Kratz; Peter Hauff; Kai Licha; Rainer Haag
Development of pH-responsive core-shell nanocarriers for delivery of therapeutic and diagnostic agents.
Bioorganic & medicinal chemistry letters 2009;19(3):1030-4.
2009: Adam L Sisson; Dirk Steinhilber; Torsten Rossow; Pia Welker; Kai Licha; Rainer Haag
Biocompatible functionalized polyglycerol microgels with cell penetrating properties.
Angewandte Chemie (International ed. in English) 2009;48(41):7540-5.
2008: Mohiuddin Abdul Quadir; Michał R Radowski; Felix Kratz; Kai Licha; Peter Hauff; Rainer Haag
Dendritic multishell architectures for drug and dye transport.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(3):289-94.
2008: Roman C Hillig; Stefanie Urlinger; Jörg Fanghänel; Bodo Brocks; Cornelia Haenel; Yvonne Stark; Detlev Sülzle; Dmitri I Svergun; Siegfried Baesler; Guido Malawski; Dieter Moosmayer; Andreas Menrad; Michael Schirner; Kai Licha
Fab MOR03268 triggers absorption shift of a diagnostic dye via packaging in a solvent-shielded Fab dimer interface.
Journal of molecular biology 2008;377(1):206-19.
2008: Kristof Graf; Thore Dietrich; Michael Tachezy; Frank-Detlef Scholle; Kai Licha; Philipp Stawowy; Michael Grafe; Peter Hauff; Eckart Fleck
Monitoring therapeutical intervention with ezetimibe using targeted near-infrared fluorescence imaging in experimental atherosclerosis.
Molecular imaging 2008;7(2):68-76.
2008: Jan Klohs; Andreas Wunder; Kai Licha
Near-infrared fluorescent probes for imaging vascular pathophysiology.
Basic research in cardiology 2008;103(2):144-51.
2008: Kai Licha; Michael Schirner; Gavin Henry
Optical agents.
Handbook of experimental pharmacology 2008;(185 Pt 1):203-22.
2008: Alexander Wall; Thorsten Persigehl; Peter Hauff; Kai Licha; Michael Schirner; Silke Müller; Angelika von Wallbrunn; Lars Matuszewski; Walter Heindel; Christoph Bremer
Differentiation of angiogenic burden in human cancer xenografts using a perfusion-type optical contrast agent (SIDAG).
Breast cancer research : BCR 2008;10(2):R23.
2007: Thore Dietrich; Christin Perlitz; Kai Licha; Philipp Stawowy; Kirstin Atrott; Michael Tachezy; Heike Meyborg; Carolin Stocker; Michael Gräfe; Eckart Fleck; Michael Schirner; Kristof Graf
ED-B fibronectin (ED-B) can be targeted using a novel single chain antibody conjugate and is associated with macrophage accumulation in atherosclerotic lesions.
Basic research in cardiology 2007;102(4):298-307.
2007: Jörg Meding; Matthias Urich; Kai Licha; Michael Reinhardt; Bernd Misselwitz; zahi Fayad; Hanns-Joachim Weinmann
Magnetic resonance imaging of atherosclerosis by targeting extracellular matrix deposition with Gadofluorine M.
Contrast media & molecular imaging 2007;2(3):120-9.
2007: Roman C Hillig; Siegfried Baesler; Stefanie Urlinger; Yvonne Stark; Susanne Bauer; Volker Badock; Martina Huber; Inke Bahr; Michael Schirner; Kai Licha
Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 3):217-23.
2006: Thomas Fischer; Ines Gemeinhardt; Susanne Wagner; Dorothee V Stieglitz; Jörg Schnorr; Kay-Geert A Hermann; Bernd Ebert; Diethard Petzelt; Rainer Macdonald; Kai Licha; Michael Schirner; Veit Krenn; Thomas Kamradt; Matthias Taupitz
Assessment of unspecific near-infrared dyes in laser-induced fluorescence imaging of experimental arthritis.
Academic radiology 2006;13(1):4-13.
2005: Kai Licha; Nils Debus; Sonja Emig-Vollmer; Birte Hofmann; Michael Hasbach; Dietger Stibenz; Sabine Sydow; Michael Schirner; Bernd Ebert; Diethard Petzelt; Christoph Bührer; Wolfhard Semmler; Rudolf Tauber
Optical molecular imaging of lymph nodes using a targeted vascular contrast agent.
Journal of biomedical optics 2005;10(4):41205.
2005: Christin Perlitz; Kai Licha; Frank-Detlef Scholle; Bernd Ebert; Malte Bahner; Peter Hauff; K Thomas Moesta; Michael Schirner
Comparison of two tricarbocyanine-based dyes for fluorescence optical imaging.
Journal of fluorescence 2005;15(3):443-54.
2004: Michael Schirner; Andreas Menrad; Andrew Stephens; Thomas Frenzel; Peter Hauff; Kai Licha
Molecular imaging of tumor angiogenesis.
Annals of the New York Academy of Sciences 2004;1014():67-75.
2002: Kai Licha; Björn Riefke; Bernd Ebert; Carsten Grötzinger
Cyanine dyes as contrast agents in biomedical optical imaging.
Academic radiology 2002;9 Suppl 2():S320-2.
2002: Gang Zheng; Hui Li; Kathy Yang; Dana Blessington; Kai Licha; Sissel Lund-Katz; Britton Chance; Jerry D Glickson
Tricarbocyanine cholesteryl laurates labeled LDL: new near infrared fluorescent probes (NIRFs) for monitoring tumors and gene therapy of familial hypercholesterolemia.
Bioorganic & medicinal chemistry letters 2002;12(11):1485-8.
2002: Sarah Bhargava; Kai Licha; Tobias Knaute; Bernd Ebert; Andreas Becker; Carsten Grötzinger; Carsten Hessenius; Bertram Wiedenmann; Jens Schneider-Mergener; Rudolf Volkmer-Engert
A complete substitutional analysis of VIP for better tumor imaging properties.
Journal of molecular recognition : JMR 2002;15(3):145-53.
2001: Bernd Ebert; U Sukowski; Dirk Grosenick; Heidrun Wabnitz; K Thomas Moesta; Kai Licha; Andreas Becker; Wolfhard Semmler; Peter M Schlag; Herbert Rinneberg
Near-infrared fluorescent dyes for enhanced contrast in optical mammography: phantom experiments.
Journal of biomedical optics 2001;6(2):134-40.
2001: Andreas Becker; Carsten Hessenius; Kai Licha; Bernd Ebert; U Sukowski; Wolfhard Semmler; Bertram Wiedenmann; Carsten Grötzinger
Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands.
Nature biotechnology 2001;19(4):327-31.
2001: Kai Licha; Carsten Hessenius; Andreas Becker; Peter Henklein; M Bauer; S Wisniewski; Bertram Wiedenmann; Wolfhard Semmler
Synthesis, characterization, and biological properties of cyanine-labeled somatostatin analogues as receptor-targeted fluorescent probes.
Bioconjugate chemistry 2001;12(1):44-50.
2000: Peter Henklein; Karsten Bruns; Michael P Sherman; Uwe Tessmer; Kai Licha; Jeffrey Kopp; Carlos M C De Noronha; Warner Greene; Victor Wray; Ulrich Schubert
Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.
The Journal of biological chemistry 2000;275(41):32016-26.
2000: Kai Licha; Björn Riefke; V Ntziachristos; Andreas Becker; Britton Chance; Wolfhard Semmler
Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: synthesis, photophysical properties and spectroscopic in vivo characterization.
Photochemistry and photobiology 2000;72(3):392-8.
2000: Andreas Becker; Björn Riefke; Bernd Ebert; U Sukowski; Herbert Rinneberg; Wolfhard Semmler; Kai Licha
Macromolecular contrast agents for optical imaging of tumors: comparison of indotricarbocyanine-labeled human serum albumin and transferrin.
Photochemistry and photobiology 2000;72(2):234-41.
2000: Andreas Becker; Carsten Hessenius; Sarah Bhargava; Carsten Grötzinger; Kai Licha; Jens Schneider-Mergener; Bertram Wiedenmann; Wolfhard Semmler
Cyanine dye labeled vasoactive intestinal peptide and somatostatin analog for optical detection of gastroenteropancreatic tumors.
Annals of the New York Academy of Sciences 2000;921():275-8.
1997: Björn Riefke; Kai Licha; Wolfhard Semmler
[Contrast media for optical mammography].
Der Radiologe 1997;37(9):749-55.

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