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André Lieber

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Chung-Huei K Wang; Joan G Schellinger; Julie Shi; Leslie W Chan; David S H Chu; Russell N Johnson; André Lieber; Tae Hee Kim
The transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus.
Ines Beyer; Pascal Fender; Qinghua Feng; ZongYi Li; Jonas Persson; Hui Song; Robert Strauss; Ruan van Rensburg; Hongjie Wang; Roma Yumul; Jiri Bartek; André Lieber
Epithelial junction opener JO-1 improves monoclonal antibody therapy of cancer.
Hongjie Wang; Roma Yumul; Pascal Fender; Akseli Hemminki; Stephanie L Lara; ZongYi Li; André Lieber
Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions.

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2011: Chung-Huei K Wang; Joan G Schellinger; Julie Shi; Leslie W Chan; David S H Chu; Russell N Johnson; André Lieber; Tae Hee Kim
The transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus.
Biomaterials 2011;32(35):9536-45.
2011: Ines Beyer; Pascal Fender; Qinghua Feng; ZongYi Li; Jonas Persson; Hui Song; Robert Strauss; Ruan van Rensburg; Hongjie Wang; Roma Yumul; Jiri Bartek; André Lieber
Epithelial junction opener JO-1 improves monoclonal antibody therapy of cancer.
Cancer research 2011;71(22):7080-90.
2011: Hongjie Wang; Roma Yumul; Pascal Fender; Akseli Hemminki; Stephanie L Lara; ZongYi Li; André Lieber
Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions.
Journal of virology 2011;85(13):6390-402.
2011: Ying Liu; Sebastian Tuve; J Persson; I Beyer; R Yumul; Zong-Yi Li; Khajornsak Tragoolpua; Karl Erik Hellström; Steve R Roffler; André Lieber
Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models.
Cancer gene therapy 2011;18(6):407-18.
2011: Ines Beyer; Zongyi Li; Jonas Persson; Ying Liu; Ruan van Rensburg; Roma Yumul; Xiao-Bing Zhang; Mien-Chie Hung; André Lieber
Controlled extracellular matrix degradation in breast cancer tumors improves therapy by trastuzumab.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):479-89.
2011: Jonas Persson; Steve Roffler; Roma Yumul; Ines Beyer; Hans-Peter Kiem; ZongYi Li; André Lieber
Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models.
PloS one 2011;6(7):e22303.
2011: Robert Strauss; Zong-Yi Li; Ying Liu; Ines Beyer; Jonas Persson; Pavel Sova; Thomas Möller; Sari Pesonen; Akseli Hemminki; Petra Hamerlik; Charles W Drescher; Nicole Urban; Jiri Bartek; André Lieber
Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.
PloS one 2011;6(1):e16186.
2011: Hongjie Wang; Zong-Yi Li; Ying Liu; Jonas Persson; Ines Beyer; Thomas Möller; Dilara Koyuncu; Max R Drescher; Robert Strauss; Xiao-Bing Zhang; James K Wahl; Nicole Urban; Charles Drescher; Akseli Hemminki; Pascal Fender; André Lieber
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14.
Nature medicine 2011;17(1):96-104.
2010: Raul Alba; Angela C Bradshaw; Lynda Coughlan; Laura Denby; Robert A McDonald; Simon Waddington; Suzanne M K Buckley; Jenny A Greig; Alan L Parker; Ashley M Miller; Hongjie Wang; André Lieber; Nico van Rooijen; John H McVey; Stuart A Nicklin; Andrew H Baker
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
Blood 2010;116(15):2656-64.
2010: Hongjie Wang; Ying Liu; Zong-Yi Li; Xiaolong Fan; Akseli Hemminki; André Lieber
A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy.
Blood 2010;115(3):592-600.
2009: Robert Strauss; André Lieber
Anatomical and physical barriers to tumor targeting with oncolytic adenoviruses in vivo.
Current opinion in molecular therapeutics 2009;11(5):513-22.
2009: Sebastian Tuve; Ying Liu; Khajornsak Tragoolpua; Jeffrey Daniel Jacobs; Roma Christine Yumul; Zong-Yi Li; Robert Strauss; Karl-Erik Hellström; Mary Lenora Disis; Steve Roffler; André Lieber
In situ adenovirus vaccination engages T effector cells against cancer.
Vaccine 2009;27(31):4225-39.
2009: Robert Strauss; Pavel Sova; Ying Liu; Zong Yi Li; Sebastian Tuve; David Pritchard; Paul Brinkkoetter; Thomas Möller; Oliver Wildner; Sari Pesonen; Akseli Hemminki; Nicole Urban; Charles W Drescher; André Lieber
Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses.
Cancer research 2009;69(12):5115-25.
2009: Ying Liu; Hongjie Wang; Roma Yumul; Wentao Gao; Andrea Gambotto; Takashi Morita; Andrew Baker; Dmitry M Shayakhmetov; André Lieber
Transduction of liver metastases after intravenous injection of Ad5/35 or Ad35 vectors with and without factor X-binding protein pretreatment.
Human gene therapy 2009;20(6):621-9.
2009: ZongYi Li; Ying Liu; Sebastian Tuve; Ye Xun; Xiaolong Fan; Liang Min; Qinghua Feng; Nancy B Kiviat; Hans-Peter Kiem; Mary Leonora Disis; André Lieber
Toward a stem cell gene therapy for breast cancer.
Blood 2009;113(22):5423-33.
2009: Hongjie Wang; Sebastian Tuve; Dean D Erdman; André Lieber
Receptor usage of a newly emergent adenovirus type 14.
Virology 2009;387(2):436-41.
2008: Hongjie Wang; Ying Liu; Zongyi Li; Sebastian Tuve; Daniel Stone; Oleksandr Kalyushniy; Dmitry M Shayakhmetov; Christophe Verlinde; Thilo Stehle; John H McVey; Andrew Baker; Kah-Whye Peng; Steve R Roffler; André Lieber
In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46.
Journal of virology 2008;82(21):10567-79.
2008: Sebastian Tuve; Hongjie Wang; Jeffrey D Jacobs; Roma C Yumul; David Smith; André Lieber
Role of cellular heparan sulfate proteoglycans in infection of human adenovirus serotype 3 and 35.
PLoS pathogens 2008;4(10):e1000189.
2008: Daniel Stone; Ying Liu; Zong-Yi Li; Robert Strauss; Eric E Finn; James M Allen; Jeffrey S Chamberlain; André Lieber
Biodistribution and safety profile of recombinant adeno-associated virus serotype 6 vectors following intravenous delivery.
Journal of virology 2008;82(15):7711-5.
2008: Hongje Wang; Hua Cao; Martin Wohlfahrt; Hans-Peter Kiem; André Lieber
Tightly regulated gene expression in human hematopoietic stem cells after transduction with helper-dependent Ad5/35 vectors.
Experimental hematology 2008;36(7):823-31.
2008: Pavel Sova; Hongjie Wang; Karol Bomsztyk; George Stamatoyannopoulos; André Lieber
Role of chromatin structure in integration of helper-dependent adenoviral vectors containing the beta-globin locus control region.
Human gene therapy 2008;19(2):153-66.
2007: Hongjie Wang; Yen-Chywan Liaw; Daniel Stone; Oleksandr Kalyuzhniy; Imameddin Amiraslanov; Sebastian Tuve; Christophe Verlinde; Dmitry M Shayakhmetov; Thilo Stehle; Steve R Roffler; André Lieber
Identification of CD46 binding sites within the adenovirus serotype 35 fiber knob.
Journal of virology 2007;81(23):12785-92.
2007: Daniel Stone; Ying Liu; Zong-Yi Li; Sebastian Tuve; Robert Strauss; André Lieber
Comparison of adenoviruses from species B, C, E, and F after intravenous delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(12):2146-53.
2007: Sebastian Tuve; Bing-Mae Chen; Ying Liu; Tian-Lu Cheng; Papa Touré; Papa Salif Sow; Qinghua Feng; Nancy B Kiviat; Robert Strauss; Shaoheng Ni; Zong-Yi Li; Steve R Roffler; André Lieber
Combination of tumor site-located CTL-associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses.
Cancer research 2007;67(12):5929-39.
2007: Daniel Stone; Ying Liu; Dmitry M Shayakhmetov; Zong-Yi Li; Shaoheng Ni; André Lieber
Adenovirus-platelet interaction in blood causes virus sequestration to the reticuloendothelial system of the liver.
Journal of virology 2007;81(9):4866-71.
2007: Yi Yang; Shilin Yang; Zhengmao Ye; Jade Jaffar; Yifeng Zhou; Erin Cutter; André Lieber; Ingegerd Hellström; Karl Erik Hellström
Tumor cells expressing anti-CD137 scFv induce a tumor-destructive environment.
Cancer research 2007;67(5):2339-44.
2007: Anuj Gaggar; Dmitry M Shayakhmetov; André Lieber
Identifying functional adenovirus-host interactions using tandem mass spectrometry.
Methods in molecular medicine 2007;131():141-55.
2007: Robert Strauss; Andreas Hüser; Shaoheng Ni; Sebastian Tuve; Nancy B Kiviat; Papa Salif Sow; Christian Hofmann; André Lieber
Baculovirus-based vaccination vectors allow for efficient induction of immune responses against plasmodium falciparum circumsporozoite protein.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(1):193-202.
2006: Sebastian Tuve; Hongjie Wang; Carol Ware; Ying Liu; Anuj Gaggar; Kathrin Maria Bernt; Dmitry M Shayakhmetov; Zongyi Li; Robert Strauss; Daniel Stone; André Lieber
A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.
Journal of virology 2006;80(24):12109-20.
2006: Hongjie Wang; André Lieber
A helper-dependent capsid-modified adenovirus vector expressing adeno-associated virus rep78 mediates site-specific integration of a 27-kilobase transgene cassette.
Journal of virology 2006;80(23):11699-709.
2006: Shaoheng Ni; Anuj Gaggar; Nelson C Di Paolo; Zong-Yi Li; Ying Liu; Robert Strauss; Pavel Sova; J Morihara; Qinghua Feng; Nancy B Kiviat; Papa Touré; Papa Salif Sow; André Lieber
Evaluation of adenovirus vectors containing serotype 35 fibers for tumor targeting.
Cancer gene therapy 2006;13(12):1072-81.
2006: Alan L Parker; Simon Waddington; Campbell G Nicol; Dmitry M Shayakhmetov; Suzanne Buckley; Laura Denby; Geoffrey Kemball-Cook; Shaoheng Ni; André Lieber; John H McVey; Stuart A Nicklin; Andrew H Baker
Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.
Blood 2006;108(8):2554-61.
2006: Daniel Stone; André Lieber
New serotypes of adenoviral vectors.
Current opinion in molecular therapeutics 2006;8(5):423-31.
2006: Nelson DiPaolo; Shaoheng Ni; Anuj Gaggar; Robert Strauss; Sebastian Tuve; Zong Yi Li; Daniel Stone; Dmitry M Shayakhmetov; Nancy B Kiviat; Papa Touré; Salif Sow; Branka Horvat; André Lieber
Evaluation of adenovirus vectors containing serotype 35 fibers for vaccination.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(4):756-65.
2006: Nelson C Di Paolo; Sebastian Tuve; Shaoheng Ni; Karl Erik Hellström; Ingegerd Hellström; André Lieber
Effect of adenovirus-mediated heat shock protein expression and oncolysis in combination with low-dose cyclophosphamide treatment on antitumor immune responses.
Cancer research 2006;66(2):960-9.
2006: Daniel Stone; Nelson C Di Paolo; André Lieber
Development of group B adenoviruses as gene transfer vectors.
Biotechnology & genetic engineering reviews 2006;22():101-23.
2006: Pavel Sova; Qinghua Feng; Gary K Geiss; Troy Wood; Robert Strauss; Vania Rudolf; André Lieber; Nancy B Kiviat
Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):114-23.
2005: Hongjie Wang; Dmitry M Shayakhmetov; Tobias Leege; Michael A Harkey; Qiliang Li; Thalia Papayannopoulou; George Stamatoyannopolous; André Lieber
A capsid-modified helper-dependent adenovirus vector containing the beta-globin locus control region displays a nonrandom integration pattern and allows stable, erythroid-specific gene expression.
Journal of virology 2005;79(17):10999-1013.
2005: Shaoheng Ni; Kathrin Maria Bernt; Anuj Gaggar; Zong-Yi Li; Hans-Peter Kiem; André Lieber
Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.
Human gene therapy 2005;16(6):664-77.
2005: Anuj Gaggar; Dmitry M Shayakhmetov; M Kathryn Liszewski; John P Atkinson; André Lieber
Localization of regions in CD46 that interact with adenovirus.
Journal of virology 2005;79(12):7503-13.
2005: Dmitry M Shayakhmetov; Anuj Gaggar; Shaoheng Ni; Zong-Yi Li; André Lieber
Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity.
Journal of virology 2005;79(12):7478-91.
2005: Dmitry M Shayakhmetov; Zong-Yi Li; Shaoheng Ni; André Lieber
Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7310-9.
2005: Kathrin Maria Bernt; Shaoheng Ni; Anh-Thu Tieu; André Lieber
Assessment of a combined, adenovirus-mediated oncolytic and immunostimulatory tumor therapy.
Cancer research 2005;65(10):4343-52.
2005: Daniel Stone; Shaoheng Ni; Zong-Yi Li; Anuj Gaggar; Nelson DiPaolo; Qinghua Feng; Volker Sandig; André Lieber
Development and assessment of human adenovirus type 11 as a gene transfer vector.
Journal of virology 2005;79(8):5090-104.
2005: Dmitry M Shayakhmetov; Andrea M Eberly; Zong-Yi Li; André Lieber
Deletion of penton RGD motifs affects the efficiency of both the internalization and the endosome escape of viral particles containing adenovirus serotype 5 or 35 fiber knobs.
Journal of virology 2005;79(2):1053-61.
2004: Dmitry M Shayakhmetov; Zong-Yi Li; Anuj Gaggar; Helen Gharwan; Vladimir Ternovoi; Volker Sandig; André Lieber
Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner.
Journal of virology 2004;78(18):10009-22.
2004: Zong-Yi Li; Shaoheng Ni; Xiangling Yang; Nancy B Kiviat; André Lieber
Xenograft models for liver metastasis: Relationship between tumor morphology and adenovirus vector transduction.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(5):650-7.
2004: Dmitry M Shayakhmetov; Zong-Yi Li; Shaoheng Ni; André Lieber
Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectors.
Journal of virology 2004;78(10):5368-81.
2004: Pavel Sova; Xiao-Wei Ren; Shaoheng Ni; Kathrin Maria Bernt; Jie Mi; Nancy B Kiviat; André Lieber
A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(4):496-509.
2003: Kathrin Maria Bernt; Shaoheng Ni; Anuj Gaggar; Zong Yi Li; Dmitry M Shayakhmetov; André Lieber
The effect of sequestration by nontarget tissues on anti-tumor efficacy of systemically applied, conditionally replicating adenovirus vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(5):746-55.
2003: Anuj Gaggar; Dmitry M Shayakhmetov; André Lieber
CD46 is a cellular receptor for group B adenoviruses.
Nature medicine 2003;9(11):1408-12.
2003: Daniel Stone; Anne Furthmann; Volker Sandig; André Lieber
The complete nucleotide sequence, genome organization, and origin of human adenovirus type 11.
Virology 2003;309(1):152-65.
2003: Dmitry M Shayakhmetov; Zong-Yi Li; Vladimir Ternovoi; Anuj Gaggar; Helen Gharwan; André Lieber
The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses.
Journal of virology 2003;77(6):3712-23.
2003: Hartmut Stecher; Cheryl A Carlson; Dmitry M Shayakhmetov; André Lieber
Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeats.
Methods in molecular medicine 2003;76():135-52.
2002: Frank C Marini; Dmitry M Shayakhmetov; Helen Gharwan; André Lieber; Michael Andreeff
Advances in gene transfer into haematopoietic stem cells by adenoviral vectors.
Expert opinion on biological therapy 2002;2(8):847-56.
2002: Kathrin Maria Bernt; Dirk S Steinwaerder; Shaoheng Ni; Zong-Yi Li; Steve R Roffler; André Lieber
Enzyme-activated Prodrug Therapy Enhances Tumor-specific Replication of Adenovirus Vectors.
Cancer research 2002;62(21):6089-98.
2002: Kathrin Maria Bernt; Min Liang; Xun Ye; Shaoheng Ni; Zong-Yi Li; Sheng-Long Ye; Fang Hu; André Lieber
A new type of adenovirus vector that utilizes homologous recombination to achieve tumor-specific replication.
Journal of virology 2002;76(21):10994-1002.
2002: Cheryl A Carlson; Dmitry M Shayakhmetov; André Lieber
Restoration of a functional open reading frame by homologous recombination between two adenoviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):99-105.
2002: Cheryl A Carlson; Dmitry M Shayakhmetov; André Lieber
An adenoviral expression system for AAV rep78 using homologous recombination.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):91-8.
2002: Zong-Yi Li; Kevin Otto; Robert E Richard; Shaoheng Ni; Irina Kirillova; Nelson Fausto; C Anthony Blau; André Lieber
Dimerizer-induced proliferation of genetically modified hepatocytes.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):420-6.
2002: Dmitry M Shayakhmetov; Zong-Yi Li; Shaoheng Ni; André Lieber
Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases.
Cancer research 2002;62(4):1063-8.
2002: Dmitry M Shayakhmetov; Cheryl A Carlson; Hartmut Stecher; Qiliang Li; George Stamatoyannopoulos; André Lieber
A high-capacity, capsid-modified hybrid adenovirus/adeno-associated virus vector for stable transduction of human hematopoietic cells.
Journal of virology 2002;76(3):1135-43.
2002: Cheryl A Carlson; Dirk S Steinwaerder; Hartmut Stecher; Dmitry M Shayakhmetov; André Lieber
Rearrangements in adenoviral genomes mediated by inverted repeats.
Methods in enzymology 2002;346():277-92.
2001: Dirk S Steinwaerder; Cheryl A Carlson; André Lieber
Human papilloma virus E6 and E7 proteins support DNA replication of adenoviruses deleted for the E1A and E1B genes.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):211-6.
2001: Ken-ichi Shofuda; D Hasenstab; Richard D Kenagy; Tomoko Shofuda; Zong-Yi Li; André Lieber; Alexander W Clowes
Membrane-type matrix metalloproteinase-1 and -3 activity in primate smooth muscle cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2010-2.
2001: Hartmut Stecher; Dmitry M Shayakhmetov; George Stamatoyannopoulos; André Lieber
A capsid-modified adenovirus vector devoid of all viral genes: assessment of transduction and toxicity in human hematopoietic cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(1):36-44.
2001: J Mi; Zong-Yi Li; Shaoheng Ni; Dirk S Steinwaerder; André Lieber
Induced apoptosis supports spread of adenovirus vectors in tumors.
Human gene therapy 2001;12(10):1343-52.
2001: Patricia Yotnda; H Onishi; Helen E Heslop; Dmitry M Shayakhmetov; André Lieber; Malcolm Brenner; Alan Davis
Efficient infection of primitive hematopoietic stem cells by modified adenovirus.
Gene therapy 2001;8(12):930-7.
2001: Dirk S Steinwaerder; Cheryl A Carlson; D L Otto; Zong-Yi Li; Shaoheng Ni; André Lieber
Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector.
Nature medicine 2001;7(2):240-3.
2000: Dmitry M Shayakhmetov; André Lieber
Dependence of adenovirus infectivity on length of the fiber shaft domain.
Journal of virology 2000;74(22):10274-86.
2000: Dirk S Steinwaerder; Cheryl A Carlson; André Lieber
DNA replication of first-generation adenovirus vectors in tumor cells.
Human gene therapy 2000;11(13):1933-48.
2000: Dirk S Steinwaerder; André Lieber
Insulation from viral transcriptional regulatory elements improves inducible transgene expression from adenovirus vectors in vitro and in vivo.
Gene therapy 2000;7(7):556-67.
2000: Dmitry M Shayakhmetov; Thalia Papayannopoulou; George Stamatoyannopoulos; André Lieber
Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector.
Journal of virology 2000;74(6):2567-83.
2000: André Lieber; Mark A Kay; Zong-Yi Li
Nuclear import of moloney murine leukemia virus DNA mediated by adenovirus preterminal protein is not sufficient for efficient retroviral transduction in nondividing cells.
Journal of virology 2000;74(2):721-34.
1999: André Lieber; Dirk S Steinwaerder; Cheryl A Carlson; Mark A Kay
Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.
Journal of virology 1999;73(11):9314-24.
1999: Dirk S Steinwaerder; Cheryl A Carlson; André Lieber
Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeats.
Journal of virology 1999;73(11):9303-13.
1998: André Lieber; Cheng-Yi He; Leonard Meuse; Charis L Himeda; C Wilson; Mark A Kay
Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver.
Journal of virology 1998;72(11):9267-77.
1998: GA Patijn; André Lieber; DB Schowalter; R Schwall; Mark A Kay
Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in mice.
Hepatology (Baltimore, Md.) 1998;28(3):707-16.
1998: GA Patijn; André Lieber; Leonard Meuse; BL Winther; Mark A Kay
High-efficiency retrovirus-mediated gene transfer into the livers of mice.
Human gene therapy 1998;9(10):1449-56.
1997: André Lieber; Cheng-Yi He; Leonard Meuse; DB Schowalter; Irina Kirillova; BL Winther; Mark A Kay
The role of Kupffer cell activation and viral gene expression in early liver toxicity after infusion of recombinant adenovirus vectors.
Journal of virology 1997;71(11):8798-807.
1997: M J Vrancken Peeters; GA Patijn; André Lieber; J Perkins; Mark A Kay
Expansion of donor hepatocytes after recombinant adenovirus-induced liver regeneration in mice.
Hepatology (Baltimore, Md.) 1997;25(4):884-8.
1997: André Lieber; M Rohde; M Strauss
Selection of efficient ribozyme cleavage sites in target RNAs.
Methods in molecular biology (Clifton, N.J.) 1997;74():45-50.
1996: André Lieber; Cheng-Yi He; Irina Kirillova; Mark A Kay
Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo.
Journal of virology 1996;70(12):8944-60.
1996: André Lieber; Cheng-Yi He; Stephen Polyak; David R Gretch; Dana Barr; Mark A Kay
Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes.
Journal of virology 1996;70(12):8782-91.
1996: M J Peeters; GA Patijn; André Lieber; Leonard Meuse; Mark A Kay
Adenovirus-mediated hepatic gene transfer in mice: comparison of intravascular and biliary administration.
Human gene therapy 1996;7(14):1693-9.
1996: André Lieber; Mark A Kay
Adenovirus-mediated expression of ribozymes in mice.
Journal of virology 1996;70(5):3153-8.
1995: André Lieber; M J Peeters; A Gown; J Perkins; Mark A Kay
A modified urokinase plasminogen activator induces liver regeneration without bleeding.
Human gene therapy 1995;6(8):1029-37.
1995: André Lieber; M J Vrancken Peeters; Leonard Meuse; Nelson Fausto; J Perkins; Mark A Kay
Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6210-4.
1995: Dana Barr; J Tubb; D Ferguson; A Scaria; André Lieber; C Wilson; J Perkins; Mark A Kay
Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains.
Gene therapy 1995;2(2):151-5.
1995: André Lieber; M J Vrancken Peeters; Mark A Kay
Adenovirus-mediated transfer of the amphotropic retrovirus receptor cDNA increases retroviral transduction in cultured cells.
Human gene therapy 1995;6(1):5-11.