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Stephen Liebhaber

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Yugong Ho; Stephen A Liebhaber; Brian M Shewchuk; Nancy E Cooke
Distinct Chromatin Configurations Regulate the Initiation and the Maintenance of hGH Gene Expression.
Margaret R Fleetwood; Yugong Ho; Nancy E Cooke; Stephen A Liebhaber
DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function.
Mitsuteru Natsuizaka; Shinya Ohashi; Harry Subramanian; Kei J Nakagawa; Azal Ahmadi; Sanders Chang; Xinjun Ji; Shingo Kagawa; Andres J Klein-Szanto; Stephen A Liebhaber; Seiji Naganuma; Hiroshi Nakagawa
Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis.

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All Publications

2013: Yugong Ho; Stephen A Liebhaber; Brian M Shewchuk; Nancy E Cooke
Distinct Chromatin Configurations Regulate the Initiation and the Maintenance of hGH Gene Expression.
Molecular and cellular biology 2013;33(9):1723-34.
2012: Margaret R Fleetwood; Yugong Ho; Nancy E Cooke; Stephen A Liebhaber
DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function.
The Journal of biological chemistry 2012;287(30):25454-65.
2012: Mitsuteru Natsuizaka; Shinya Ohashi; Harry Subramanian; Kei J Nakagawa; Azal Ahmadi; Sanders Chang; Xinjun Ji; Shingo Kagawa; Andres J Klein-Szanto; Stephen A Liebhaber; Seiji Naganuma; Hiroshi Nakagawa
Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(6):2620-30.
2012: Eung Jae Yoo; Nancy E Cooke; Stephen A Liebhaber
An RNA-independent linkage of noncoding transcription to long-range enhancer function.
Molecular and cellular biology 2012;32(10):2020-9.
2012: Isabel Peixeiro; Cristina Barbosa; Stephen A Liebhaber; Ana Luísa Silva; Angela Inácio; Luísa Romão
Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations.
Nucleic acids research 2012;40(3):1160-73.
2011: Xinjun Ji; Jian Kong; Stephen A Liebhaber
An RNA-protein complex links enhanced nuclear 3' processing with cytoplasmic mRNA stabilization.
The EMBO journal 2011;30(13):2622-33.
2011: Yugong Ho; Stephen A Liebhaber; Nancy E Cooke
The role of the hGH locus control region in somatotrope restriction of hGH-N gene expression.
Molecular endocrinology (Baltimore, Md.) 2011;25(5):877-84.
2009: Shelly A Waggoner; Gregg J Johannes; Stephen A Liebhaber
Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest.
The Journal of biological chemistry 2009;284(14):9039-49.
2009: R B Hamanaka; Ekaterina Bobrovnikova-Marjon; X Ji; Stephen A Liebhaber; J Alan Diehl
PERK-dependent regulation of IAP translation during ER stress.
Oncogene 2009;28(6):910-20.
2008: Yugong Ho; Aleksey Tadevosyan; Stephen A Liebhaber; Nancy E Cooke
The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression.
EMBO reports 2008;9(9):891-8.
2008: Regina M Young; Shang-Jui Wang; John D Gordan; Xinjun Ji; Stephen A Liebhaber; M Celeste Simon
Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism.
The Journal of biological chemistry 2008;283(24):16309-19.
2008: Ana Luísa Silva; Patrícia Ribeiro; Angela Inácio; Stephen A Liebhaber; Luísa Romão
Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay.
RNA (New York, N.Y.) 2008;14(3):563-76.
2007: Michele R Roullet; Rachel Sargent; Theresa Pasha; Isabela Cajiao; Rebecca L Elstrom; Treasa Smith; Stephen A Liebhaber; Paul Zhang; Adam Bagg
ZAP70 expression assessed by immunohistochemistry on peripheral blood: a simple prognostic assay for patients with chronic lymphocytic leukemia.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2007;15(4):471-6.
2007: Tomoko Hiroki; Stephen A Liebhaber; Nancy E Cooke
An intronic locus control region plays an essential role in the establishment of an autonomous hepatic chromatin domain for the human vitamin D-binding protein gene.
Molecular and cellular biology 2007;27(21):7365-80.
2007: Atsushi P Kimura; Daria Sizova; Stuart Handwerger; Nancy E Cooke; Stephen A Liebhaber
Epigenetic activation of the human growth hormone gene cluster during placental cytotrophoblast differentiation.
Molecular and cellular biology 2007;27(18):6555-68.
2007: Isabela Cajiao; Rachel Sargent; Rebecca L Elstrom; Nancy E Cooke; Adam Bagg; Stephen A Liebhaber
Igbeta(CD79b) mRNA expression in chronic lymphocytic leukaemia cells correlates with immunoglobulin heavy chain gene mutational status but does not serve as an independent predictor of clinical severity.
American journal of hematology 2007;82(8):712-20.
2007: Jian Kong; Stephen A Liebhaber
A cell type-restricted mRNA surveillance pathway triggered by ribosome extension into the 3' untranslated region.
Nature structural & molecular biology 2007;14(7):670-6.
2007: Thimmaiah P Chendrimada; Kenneth J Finn; Xinjun Ji; David Baillat; Richard I Gregory; Stephen A Liebhaber; Amy E Pasquinelli; Ramin Shiekhattar
MicroRNA silencing through RISC recruitment of eIF6.
Nature 2007;447(7146):823-8.
2007: Xinjun Ji; Jian Kong; Russ P Carstens; Stephen A Liebhaber
The 3' untranslated region complex involved in stabilization of human alpha-globin mRNA assembles in the nucleus and serves an independent role as a splice enhancer.
Molecular and cellular biology 2007;27(9):3290-302.
2006: Ana Luísa Silva; Francisco J C Pereira; Ana Morgado; Jian Kong; Rute Martins; Paula Faustino; Stephen A Liebhaber; Luísa Romão
The canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence context.
RNA (New York, N.Y.) 2006;12(12):2160-70.
2006: Brian M Shewchuk; Yugong Ho; Stephen A Liebhaber; Nancy E Cooke
A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functions.
Molecular and cellular biology 2006;26(17):6535-46.
2006: Yugong Ho; Felice Elefant; Stephen A Liebhaber; Nancy E Cooke
Locus control region transcription plays an active role in long-range gene activation.
Molecular cell 2006;23(3):365-75.
2006: Jian Kong; Marina Sumaroka; Dawn L Eastmond; Stephen A Liebhaber
Shared stabilization functions of pyrimidine-rich determinants in the erythroid 15-lipoxygenase and alpha-globin mRNAs.
Molecular and cellular biology 2006;26(15):5603-14.
2006: Eung Jae Yoo; Isabela Cajiao; Jeong-Seon Kim; Atsushi P Kimura; Aiwen Zhang; Nancy E Cooke; Stephen A Liebhaber
Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions.
Molecular and cellular biology 2006;26(15):5569-79.
2006: Tomoko Hiroki; Young-Han Song; Stephen A Liebhaber; Nancy E Cooke
The human vitamin D-binding protein gene contains locus control determinants sufficient for autonomous activation in hepatic chromatin.
Nucleic acids research 2006;34(8):2154-65.
2005: Rona S Weinberg; Xinjun Ji; Millicent Sutton; Susan P Perrine; Yelena Galperin; Qiliang Li; Stephen A Liebhaber; George Stamatoyannopoulos; George F Atweh
Butyrate increases the efficiency of translation of gamma-globin mRNA.
Blood 2005;105(4):1807-9.
2004: Isabela Cajiao; Aiwen Zhang; Eung Jae Yoo; Nancy E Cooke; Stephen A Liebhaber
Bystander gene activation by a locus control region.
The EMBO journal 2004;23(19):3854-63.
2004: Angela Inácio; Ana Luísa Silva; Joana Pinto; Xinjun Ji; Ana Morgado; Fátima Almeida; Paula Faustino; João Lavinha; Stephen A Liebhaber; Luísa Romão
Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.
The Journal of biological chemistry 2004;279(31):32170-80.
2004: Yuhua Su; Rita J Balice-Gordon; Darren M Hess; Douglas S Landsman; Jeremy Minarcik; Jeffrey Golden; Ivy Hurwitz; Stephen A Liebhaber; Nancy E Cooke
Neurobeachin is essential for neuromuscular synaptic transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(14):3627-36.
2004: Atsushi P Kimura; Stephen A Liebhaber; Nancy E Cooke
Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation.
Molecular endocrinology (Baltimore, Md.) 2004;18(4):1018-32.
2004: Yugong Ho; Stephen A Liebhaber; Nancy E Cooke
Activation of the human GH gene cluster: roles for targeted chromatin modification.
Trends in endocrinology and metabolism: TEM 2004;15(1):40-5.
2003: Alexander N Chkheidze; Stephen A Liebhaber
A novel set of nuclear localization signals determine distributions of the alphaCP RNA-binding proteins.
Molecular and cellular biology 2003;23(23):8405-15.
2003: Shelly A Waggoner; Stephen A Liebhaber
Identification of mRNAs associated with alphaCP2-containing RNP complexes.
Molecular and cellular biology 2003;23(19):7055-67.
2003: Shelly A Waggoner; Stephen A Liebhaber
Regulation of alpha-globin mRNA stability.
Experimental biology and medicine (Maywood, N.J.) 2003;228(4):387-95.
2003: Jian Kong; Xinjun Ji; Stephen A Liebhaber
The KH-domain protein alpha CP has a direct role in mRNA stabilization independent of its cognate binding site.
Molecular and cellular biology 2003;23(4):1125-34.
2003: Xinjun Ji; Jian Kong; Stephen A Liebhaber
In vivo association of the stability control protein alphaCP with actively translating mRNAs.
Molecular and cellular biology 2003;23(3):899-907.
2002: Brian M Shewchuk; Stephen A Liebhaber; Nancy E Cooke
Specification of unique Pit-1 activity in the hGH locus control region.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11784-9.
2002: Aleksandr V Makeyev; Dawn L Eastmond; Stephen A Liebhaber
Targeting a KH-domain protein with RNA decoys.
RNA (New York, N.Y.) 2002;8(9):1160-73.
2002: Aleksandr V Makeyev; Stephen A Liebhaber
The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms.
RNA (New York, N.Y.) 2002;8(3):265-78.
2002: Yugong Ho; Felice Elefant; Nancy E Cooke; Stephen A Liebhaber
A defined locus control region determinant links chromatin domain acetylation with long-range gene activation.
Molecular cell 2002;9(2):291-302.
2002: Peter White; Stephen A Liebhaber; Nancy E Cooke
129X1/SvJ mouse strain has a novel defect in inflammatory cell recruitment.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):869-74.
2001: Brian M Shewchuk; Nancy E Cooke; Stephen A Liebhaber
The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions.
Nucleic acids research 2001;29(16):3356-61.
2001: T Thisted; D L Lyakhov; Stephen A Liebhaber
Optimized RNA targets of two closely related triple KH domain proteins, heterogeneous nuclear ribonucleoprotein K and alphaCP-2KL, suggest Distinct modes of RNA recognition.
The Journal of biological chemistry 2001;276(20):17484-96.
2000: Felice Elefant; Y Su; Stephen A Liebhaber; Nancy E Cooke
Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region.
The EMBO journal 2000;19(24):6814-22.
2000: Aleksandr V Makeyev; Stephen A Liebhaber
Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins.
Genomics 2000;67(3):301-16.
2000: Felice Elefant; Nancy E Cooke; Stephen A Liebhaber
Targeted recruitment of histone acetyltransferase activity to a locus control region.
The Journal of biological chemistry 2000;275(18):13827-34.
2000: Y Su; Stephen A Liebhaber; Nancy E Cooke
The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse.
The Journal of biological chemistry 2000;275(11):7902-9.
1999: Brian M Shewchuk; Sylvia Asa; Nancy E Cooke; Stephen A Liebhaber
Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation.
The Journal of biological chemistry 1999;274(50):35725-33.
1999: Aleksandr V Makeyev; Alexander N Chkheidze; Stephen A Liebhaber
A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog.
The Journal of biological chemistry 1999;274(35):24849-57.
1999: Alexander N Chkheidze; D L Lyakhov; Aleksandr V Makeyev; J Morales; Jian Kong; Stephen A Liebhaber
Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP.
Molecular and cellular biology 1999;19(7):4572-81.
1999: Young-Han Song; A K Naumova; Stephen A Liebhaber; Nancy E Cooke
Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster.
Genome research 1999;9(6):581-7.
1999: Z Wang; Stephen A Liebhaber
A 3'-flanking NF-kappaB site mediates developmental silencing of the human zeta-globin gene.
The EMBO journal 1999;18(8):2218-28.
1999: F F Safadi; P Thornton; H Magiera; Bruce W Hollis; M Gentile; JG Haddad; Stephen A Liebhaber; Nancy E Cooke
Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein.
The Journal of clinical investigation 1999;103(2):239-51.
1998: J Eric Russell; Stephen A Liebhaber
Reversal of lethal alpha- and beta-thalassemias in mice by expression of human embryonic globins.
Blood 1998;92(9):3057-63.
1998: Young-Han Song; K Ray; Stephen A Liebhaber; Nancy E Cooke
Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1beta.
The Journal of biological chemistry 1998;273(43):28408-18.
1998: idriss bennani-baiti; Sylvia Asa; D Song; R Iratni; Stephen A Liebhaber; Nancy E Cooke
DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10655-60.
1998: J Eric Russell; A E Lee; Stephen A Liebhaber
Full developmental silencing of the embryonic zeta-globin gene reflects instability of its mRNA.
Annals of the New York Academy of Sciences 1998;850():386-90.
1998: Stephen A Liebhaber; J Eric Russell
Expression and developmental control of the human alpha-globin gene cluster.
Annals of the New York Academy of Sciences 1998;850():54-63.
1998: J Eric Russell; J Morales; Aleksandr V Makeyev; Stephen A Liebhaber
Sequence divergence in the 3' untranslated regions of human zeta- and alpha-globin mRNAs mediates a difference in their stabilities and contributes to efficient alpha-to-zeta gene development switching.
Molecular and cellular biology 1998;18(4):2173-83.
1998: idriss bennani-baiti; Nancy E Cooke; Stephen A Liebhaber
Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene.
Genomics 1998;48(2):258-64.
1997: Martin Holcik; Stephen A Liebhaber
Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2410-4.
1997: J Morales; J Eric Russell; Stephen A Liebhaber
Destabilization of human alpha-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail.
The Journal of biological chemistry 1997;272(10):6607-13.
1997: Stephen A Liebhaber
mRNA stability and the control of gene expression.
Nucleic acids symposium series 1997;(36):29-32.
1997: J Eric Russell; J Morales; Stephen A Liebhaber
The role of mRNA stability in the control of globin gene expression.
Progress in nucleic acid research and molecular biology 1997;57():249-87.
1996: X Wang; Stephen A Liebhaber
Complementary change in cis determinants and trans factors in the evolution of an mRNP stability complex.
The EMBO journal 1996;15(18):5040-51.
1996: J Eric Russell; Stephen A Liebhaber
The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region.
Blood 1996;87(12):5314-23.
1996: Stephen A Liebhaber; Z Wang; F E Cash; B Monks; J Eric Russell
Developmental silencing of the embryonic zeta-globin gene: concerted action of the promoter and the 3'-flanking region combined with stage-specific silencing by the transcribed segment.
Molecular and cellular biology 1996;16(6):2637-46.
1995: Beverly Jones; B R Monks; Stephen A Liebhaber; Nancy E Cooke
The human growth hormone gene is regulated by a multicomponent locus control region.
Molecular and cellular biology 1995;15(12):7010-21.
1995: idriss bennani-baiti; Beverly Jones; Stephen A Liebhaber; Nancy E Cooke
Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.
Genomics 1995;29(3):647-52.
1995: M Kiledjian; X Wang; Stephen A Liebhaber
Identification of two KH domain proteins in the alpha-globin mRNP stability complex.
The EMBO journal 1995;14(17):4357-64.
1995: I M Weiss; Stephen A Liebhaber
Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated region.
Molecular and cellular biology 1995;15(5):2457-65.
1995: X Wang; M Kiledjian; I M Weiss; Stephen A Liebhaber
Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability.
Molecular and cellular biology 1995;15(3):1769-77.
1994: I M Weiss; Stephen A Liebhaber
Erythroid cell-specific determinants of alpha-globin mRNA stability.
Molecular and cellular biology 1994;14(12):8123-32.
1994: R Feuerstein; X Wang; D Song; Nancy E Cooke; Stephen A Liebhaber
The LIM/double zinc-finger motif functions as a protein dimerization domain.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10655-9.
1994: P A Estes; Margrit Urbanek; J Ray; Stephen A Liebhaber; Nancy E Cooke
Alternative splice site selection in the human growth hormone gene transcript and synthesis of the 20 kDa isoform: role of higher order transcript structure.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1994;399():42-7; discussion 48.
1993: Margrit Urbanek; J Eric Russell; Nancy E Cooke; Stephen A Liebhaber
Functional characterization of the alternatively spliced, placental human growth hormone receptor.
The Journal of biological chemistry 1993;268(25):19025-32.
1993: J Eric Russell; Stephen A Liebhaber
Double-stranded RNA triggers generalized translational arrest in Xenopus oocytes.
Biochemical and biophysical research communications 1993;194(2):892-900.
1992: X Wang; K Ray; J Szpirer; G Levan; Stephen A Liebhaber; Nancy E Cooke
Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism.
Genomics 1992;14(2):391-7.
1992: M Albitar; A Care; C Peschle; Stephen A Liebhaber
Developmental switching of messenger RNA expression from the human alpha-globin cluster: fetal/adult pattern of theta-globin gene expression.
Blood 1992;80(6):1586-91.
1992: Stephen A Liebhaber; F Cash; S S Eshleman
Translation inhibition by an mRNA coding region secondary structure is determined by its proximity to the AUG initiation codon.
Journal of molecular biology 1992;226(3):609-21.
1992: P A Estes; Nancy E Cooke; Stephen A Liebhaber
A native RNA secondary structure controls alternative splice-site selection and generates two human growth hormone isoforms.
The Journal of biological chemistry 1992;267(21):14902-8.
1992: J N MacLeod; A K Lee; Stephen A Liebhaber; Nancy E Cooke
Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.
The Journal of biological chemistry 1992;267(20):14219-26.
1992: X Wang; G Lee; Stephen A Liebhaber; Nancy E Cooke
Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.
The Journal of biological chemistry 1992;267(13):9176-84.
1992: M Albitar; F E Cash; C Peschle; Stephen A Liebhaber
Developmental switch in the relative expression of the alpha 1- and alpha 2-globin genes in humans and in transgenic mice.
Blood 1992;79(9):2471-4.
1992: L Romao; F Cash; I Weiss; Stephen A Liebhaber; Mario Pirastu; R Galanello; A Loi; E Paglietti; P Ioannou; Antonio Cao
Human alpha-globin gene expression is silenced by terminal truncation of chromosome 16p beginning immediately 3' of the zeta-globin gene.
Human genetics 1992;89(3):323-8.
1992: Margrit Urbanek; J N MacLeod; Nancy E Cooke; Stephen A Liebhaber
Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript.
Molecular endocrinology (Baltimore, Md.) 1992;6(2):279-87.
1991: Kazuko Nishikura; C Yoo; U Kim; J M Murray; P A Estes; F E Cash; Stephen A Liebhaber
Substrate specificity of the dsRNA unwinding/modifying activity.
The EMBO journal 1991;10(11):3523-32.
1991: L Romao; L Osorio-Almeida; D R Higgs; J Lavinha; Stephen A Liebhaber
Alpha-thalassemia resulting from deletion of regulatory sequences far upstream of the alpha-globin structural genes.
Blood 1991;78(6):1589-95.
1991: M Albitar; M Katsumata; Stephen A Liebhaber
Human alpha-globin genes demonstrate autonomous developmental regulation in transgenic mice.
Molecular and cellular biology 1991;11(7):3786-94.
1991: J N MacLeod; Stephen A Liebhaber; M H MacGillivray; Nancy E Cooke
Identification of a splice-site mutation in the human growth hormone-variant gene.
American journal of human genetics 1991;48(6):1168-74.
1991: J N MacLeod; I Worsley; J Ray; H G Friesen; Stephen A Liebhaber; Nancy E Cooke
Human growth hormone-variant is a biologically active somatogen and lactogen.
Endocrinology 1991;128(3):1298-302.
1990: I Weiss; F E Cash; M B Coleman; A Pressley; J G Adams; T Sanguansermsri; Stephen A Liebhaber; Martin H Steinberg
Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg)
Blood 1990;76(12):2630-6.
1990: Stephen A Liebhaber; E U Griese; I Weiss; F E Cash; H Ayyub; D R Higgs; J Horst
Inactivation of human alpha-globin gene expression by a de novo deletion located upstream of the alpha-globin gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9431-5.
1990: P A Estes; Nancy E Cooke; Stephen A Liebhaber
A difference in the splicing patterns of the closely related normal and variant human growth hormone gene transcripts is determined by a minimal sequence divergence between two potential splice-acceptor sites.
The Journal of biological chemistry 1990;265(32):19863-70.
1990: Stephen A Liebhaber; J G Emery; Margrit Urbanek; X K Wang; Nancy E Cooke
Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif.
Nucleic acids research 1990;18(13):3871-9.
1990: J Ray; H Okamura; P A Kelly; Nancy E Cooke; Stephen A Liebhaber
Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone.
The Journal of biological chemistry 1990;265(14):7939-44.
1990: J Ray; H Okamura; P A Kelly; Stephen A Liebhaber; Nancy E Cooke
Alteration in the receptor binding specificity of human growth hormone by genomic exon exchange.
Molecular endocrinology (Baltimore, Md.) 1990;4(1):101-7.
1989: F E Cash; N Monplaisir; M Goossens; Stephen A Liebhaber
Locus assignment of two alpha-globin structural mutants from the Caribbean basin: alpha Fort de France (alpha 45 Arg) and alpha Spanish Town (alpha 27 Val).
Blood 1989;74(2):833-5.
1989: J Ray; Beverly Jones; Stephen A Liebhaber; Nancy E Cooke
Glycosylated human growth hormone variant.
Endocrinology 1989;125(1):566-8.
1989: Stephen A Liebhaber; Margrit Urbanek; J Ray; R S Tuan; Nancy E Cooke
Characterization and histologic localization of human growth hormone-variant gene expression in the placenta.
The Journal of clinical investigation 1989;83(6):1985-91.
1989: Stephen A Liebhaber
Alpha thalassemia.
Hemoglobin 1989;13(7-8):685-731.
1988: Nancy E Cooke; J Ray; M A Watson; P A Estes; B A Kuo; Stephen A Liebhaber
Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns.
The Journal of clinical investigation 1988;82(1):270-5.
1988: Nancy E Cooke; J Ray; J G Emery; Stephen A Liebhaber
Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins.
The Journal of biological chemistry 1988;263(18):9001-6.
1988: S H Shakin-Eshleman; Stephen A Liebhaber
Influence of duplexes 3' to the mRNA initiation codon on the efficiency of monosome formation.
Biochemistry 1988;27(11):3975-82.
1988: Stephen A Liebhaber; F E Cash; D B Cornfield
Evidence for posttranslational control of Hb C synthesis in an individual with Hb C trait and alpha-thalassemia.
Blood 1988;71(2):502-4.
1987: S H Shakin; Stephen A Liebhaber
Opposite responses of rabbit and human globin mRNAs to translational inhibition by cap analogues.
Biochemistry 1987;26(22):7188-93.
1987: Paolo Moi; F E Cash; Stephen A Liebhaber; Antonio Cao; Mario Pirastu
An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.
The Journal of clinical investigation 1987;80(5):1416-21.
1987: Stephen A Liebhaber; M B Coleman; J G Adams; F E Cash; Martin H Steinberg
Molecular basis for nondeletion alpha-thalassemia in American blacks. Alpha 2(116GAG----UAG).
The Journal of clinical investigation 1987;80(1):154-9.
1986: S H Shakin; Stephen A Liebhaber
Destabilization of messenger RNA/complementary DNA duplexes by the elongating 80 S ribosome.
The Journal of biological chemistry 1986;261(34):16018-25.
1986: Stephen A Liebhaber; F E Cash; S K Ballas
Human alpha-globin gene expression. The dominant role of the alpha 2-locus in mRNA and protein synthesis.
The Journal of biological chemistry 1986;261(32):15327-33.
1986: S H Shakin; Stephen A Liebhaber
Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes.
The Journal of clinical investigation 1986;78(4):1125-9.
1985: Stephen A Liebhaber; F E Cash; D M Main
Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion.
The Journal of clinical investigation 1985;76(3):1057-64.
1985: Stephen A Liebhaber; F E Cash
Locus assignment of alpha-globin structural mutations by hybrid-selected translation.
The Journal of clinical investigation 1985;75(1):64-70.
1984: Stephen A Liebhaber; F E Cash; S H Shakin
Translationally associated helix-destabilizing activity in rabbit reticulocyte lysate.
The Journal of biological chemistry 1984;259(24):15597-602.
1984: Stephen A Liebhaber; E F Rappaport; F E Cash; S K Ballas; E Schwartz; S Surrey
Hemoglobin I mutation encoded at both alpha-globin loci on the same chromosome: concerted evolution in the human genome.
Science (New York, N.Y.) 1984;226(4681):1449-51.