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Danielle Liénard

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Andrea Kuemmerle; Laurent A Decosterd; Thierry Buclin; Danielle Liénard; Roger Stupp; Pierre-Guy Chassot; François Mosimann; Ferdy Lejeune
A phase I pharmacokinetic study of hypoxic abdominal stop-flow perfusion with gemcitabine in patients with advanced pancreatic cancer and refractory malignant ascites.
Stéphane Cherix; Mélanie Speiser; Maurice Matter; Wassim Raffoul; Danielle Liénard; Nicolas Theumann; Elyazid Mouhsine; René-Olivier Mirimanoff; Serge Leyvraz; Ferdy J Lejeune; Pierre-François Leyvraz
Isolated limb perfusion with tumor necrosis factor and melphalan for non-resectable soft tissue sarcomas: long-term results on efficacy and limb salvage in a selected group of patients.
D Roulin; Maurice Matter; Pierre Bady; Danielle Liénard; Oliver Gugerli; Ariane Boubaker; Luc Bron; Ferdy J Lejeune
Prognostic value of sentinel node biopsy in 327 prospective melanoma patients from a single institution.

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All Publications

2009: Andrea Kuemmerle; Laurent A Decosterd; Thierry Buclin; Danielle Liénard; Roger Stupp; Pierre-Guy Chassot; François Mosimann; Ferdy Lejeune
A phase I pharmacokinetic study of hypoxic abdominal stop-flow perfusion with gemcitabine in patients with advanced pancreatic cancer and refractory malignant ascites.
Cancer chemotherapy and pharmacology 2009;63(2):331-41.
2008: Stéphane Cherix; Mélanie Speiser; Maurice Matter; Wassim Raffoul; Danielle Liénard; Nicolas Theumann; Elyazid Mouhsine; René-Olivier Mirimanoff; Serge Leyvraz; Ferdy J Lejeune; Pierre-François Leyvraz
Isolated limb perfusion with tumor necrosis factor and melphalan for non-resectable soft tissue sarcomas: long-term results on efficacy and limb salvage in a selected group of patients.
Journal of surgical oncology 2008;98(3):148-55.
2008: D Roulin; Maurice Matter; Pierre Bady; Danielle Liénard; Oliver Gugerli; Ariane Boubaker; Luc Bron; Ferdy J Lejeune
Prognostic value of sentinel node biopsy in 327 prospective melanoma patients from a single institution.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2008;34(6):673-9.
2007: Maurice Matter; Marie Nicod Lalonde; Mohamed Allaoua; Ariane Boubaker; Danielle Liénard; Oliver Gugerli; Jean-Philippe Cerottini; Hanifa Bouzourene; Angelika Bischof Delaloye; Ferdinand Lejeune
The role of interval nodes in sentinel lymph node mapping and dissection for melanoma patients.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(10):1607-13.
2007: Catherine Barbey; Petra Baumgaertner; Estelle Devevre; Verena Rubio-Godoy; Laurent Derré; Gabriel Bricard; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer; Daniel E Speiser
IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3566-74.
2006: Daniel E Speiser; Petra Baumgaertner; Catherine Barbey; Verena Rubio-Godoy; Alexandre Moulin; Patricia Corthesy; Estelle Devevre; Pierre-Yves Dietrich; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer
A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1338-48.
2006: Petra Baumgaertner; Nathalie Rufer; Estelle Devevre; Laurent Derré; Donata Rimoldi; Christine Geldhof; Verena Voelter; Danielle Liénard; Pedro Romero; Daniel E Speiser
Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.
Cancer research 2006;66(4):1912-6.
2006: Ferdy J Lejeune; Danielle Liénard; Maurice Matter; Curzio Rüegg
Efficiency of recombinant human TNF in human cancer therapy.
Cancer immunity 2006;6():6.
2005: Nicolas van Baren; Marie-Claude Bonnet; Brigitte Dréno; Amir Khammari; Thierry Dorval; Sophie Piperno-Neumann; Danielle Liénard; Daniel Speiser; Marie Marchand; Vincent G Brichard; Bernard Escudier; Sylvie Négrier; Pierre-Yves Dietrich; Dominique Maraninchi; Susanne Osanto; Ralf G Meyer; Gerd Ritter; Philippe Moingeon; Jim Tartaglia; Pierre van der Bruggen; Pierre G Coulie; Thierry Boon
Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(35):9008-21.
2005: Daniel E Speiser; Danielle Liénard; Nathalie Rufer; Verena Rubio-Godoy; Donata Rimoldi; Ferdy Lejeune; Arthur M Krieg; Jean-Charles Cerottini; Pedro Romero
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.
The Journal of clinical investigation 2005;115(3):739-46.
2004: Danielle Liénard; Donata Rimoldi; Marie Marchand; Pierre-Yves Dietrich; Nicolas van Baren; Christine Geldhof; Pascal Batard; Philippe Guillaume; Maha Ayyoub; Mikaël J Pittet; Alfred Zippelius; Katharina Fleischhauer; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer immunity 2004;4():4.
2004: Alfred Zippelius; Pascal Batard; Verena Rubio-Godoy; Gilles Bioley; Danielle Liénard; Ferdy Lejeune; Donata Rimoldi; Philippe Guillaume; Norbert Meidenbauer; Andreas Mackensen; Nathalie Rufer; Norbert Lubenow; Daniel Speiser; Jean-Charles Cerottini; Pedro Romero; Mikaël J Pittet
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.
Cancer research 2004;64(8):2865-73.
2004: Mojgan Movassagh; Alain Spatz; Jean Davoust; Serge Lebecque; Pedro Romero; Mikaël Pittet; Donata Rimoldi; Danielle Liénard; Oliver Gugerli; Laurent Ferradini; Caroline Robert; Marie-Françoise Avril; Laurence Zitvogel; Eric Angevin
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Cancer research 2004;64(6):2192-8.
2003: Daniel E Speiser; Mikaël J Pittet; Donata Rimoldi; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Seminars in cancer biology 2003;13(6):461-72.
2003: VAIOS KARANIKAS; Christophe Lurquin; Didier Colau; Nicolas van Baren; Charles De Smet; Bernard Lethé; Thierry Connerotte; Véronique Corbière; Marie-Ange Demoitié; Danielle Liénard; Brigitte Dréno; Thierry Velu; Thierry Boon; Pierre G Coulie
Monoclonal anti-MAGE-3 CTL responses in melanoma patients displaying tumor regression after vaccination with a recombinant canarypox virus.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(9):4898-904.
2003: Danila Valmori; Valérie Dutoit; Maha Ayyoub; Donata Rimoldi; Philippe Guillaume; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.
Cancer immunity 2003;3():15.
2003: Donata Rimoldi; Robert Lemoine; Anne-Marie Kurt; Suzanne Salvi; Magali Berset; Maurice Matter; Bruno Roche; Jean-Philippe Cerottini; David Guggisberg; Joachim Krischer; Ralph Braun; Jean-Pierre Willi; Christian Antonescu; Daniel O Slosman; Ferdy J Lejeune; Danielle Liénard
Detection of micrometastases in sentinel lymph nodes from melanoma patients: direct comparison of multimarker molecular and immunopathological methods.
Melanoma research 2003;13(5):511-20.
2003: Donata Rimoldi; Suzanne Salvi; Danielle Liénard; Ferdy J Lejeune; Daniel Speiser; Leonidas Zografos; Jean-Charles Cerottini
Lack of BRAF mutations in uveal melanoma.
Cancer research 2003;63(18):5712-5.
2003: Daniel E Speiser; Donata Rimoldi; Pascal Batard; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Disease-driven T cell activation predicts immune responses to vaccination against melanoma.
Cancer immunity 2003;3():12.
2003: Maha Ayyoub; Alfred Zippelius; Mikaël J Pittet; Donata Rimoldi; Danila Valmori; Jean-Charles Cerottini; Pedro Romero; Ferdy Lejeune; Danielle Liénard; Daniel E Speiser
Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):669-77.
2002: Pedro Romero; Mikael Pittet; Valérie Dutoit; Alfred Zippelius; Danielle Liénard; Ferdy Lejeune; Philippe Guillaume; Donata Rimoldi; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini
Therapeutic cancer vaccines based on molecularly defined human tumor antigens.
Vaccine 2002;20 Suppl 4():A2-7.
2002: Pedro Romero; Danila Valmori; Mikaël J Pittet; Alfred Zippelius; Donata Rimoldi; Frédéric Lévy; Valérie Dutoit; Maha Ayyoub; Verena Rubio-Godoy; Olivier Michielin; Philippe Guillaume; Pascal Batard; Immanuel F Luescher; Ferdy Lejeune; Danielle Liénard; Nathalie Rufer; Pierre-Yves Dietrich; Daniel E Speiser; Jean-Charles Cerottini
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Immunological reviews 2002;188():81-96.
2002: Danila Valmori; Valérie Dutoit; Valerie Schnuriger; Anne-Lise Quiquerez; Mikaël J Pittet; Philippe Guillaume; Verena Rubio-Godoy; Paul R Walker; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Pierre-Yves Dietrich
Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4231-40.
2002: Danila Valmori; Carmen Scheibenbogen; Valérie Dutoit; Dirk Nagorsen; Anne Marie Asemissen; Verena Rubio-Godoy; Donata Rimoldi; Philippe Guillaume; Pedro Romero; Dirk Schadendorf; Martin Lipp; Pierre-Yves Dietrich; Eckhard Thiel; Jean-Charles Cerottini; Danielle Liénard; Ulrich Keilholz
Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.
Cancer research 2002;62(6):1743-50.
2002: Daniel E Speiser; Danielle Liénard; Mikaël J Pittet; Pascal Batard; Donata Rimoldi; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
European journal of immunology 2002;32(3):731-41.
2002: Alfred Zippelius; Mikaël J Pittet; Pascal Batard; Nathalie Rufer; Magda De Smedt; Philippe Guillaume; Kim Ellefsen; Danila Valmori; Danielle Liénard; Jean Plum; H Robson MacDonald; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
The Journal of experimental medicine 2002;195(4):485-94.
2002: Valérie Dutoit; Verena Rubio-Godoy; Marie-Agnès Doucey; Pascal Batard; Danielle Liénard; Donata Rimoldi; Daniel Speiser; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1167-71.
2002: David Guggisberg; Jean-Philippe Cerottini; Joachim Krischer; Ralph Braun; Pierre-Yves Dietrich; Danielle Liénard
[Recommendations for the management of melanoma].
Revue médicale de la Suisse romande 2002;122(1):5-8.
2001: Daniel E Speiser; Marco COLONna; Maha Ayyoub; M Cella; Mikaël J Pittet; Pascal Batard; Danila Valmori; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6165-70.
2001: Ferdy J Lejeune; B B Kroon; Franco Di Filippo; H J Hoekstra; mario santinami; Danielle Liénard; Alexander M M Eggermont
Isolated limb perfusion: the European experience.
Surgical oncology clinics of North America 2001;10(4):821-32, ix.
2001: Maha Ayyoub; M Migliaccio; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Frédéric Lévy; Daniel E Speiser; Danila Valmori
Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.
European journal of immunology 2001;31(9):2642-51.
2001: Valérie Dutoit; Verena Rubio-Godoy; Pierre-Yves Dietrich; A L Quiqueres; Valerie Schnuriger; Donata Rimoldi; Danielle Liénard; Daniel Speiser; Philippe Guillaume; Pascal Batard; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity.
Cancer research 2001;61(15):5850-6.
2001: M J Pittet; Daniel E Speiser; D Valmori; D Rimoldi; Danielle Liénard; F Lejeune; J C Cerottini; P Romero
Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients.
International immunopharmacology 2001;1(7):1235-47.
2001: Mikaël J Pittet; Alfred Zippelius; Daniel E Speiser; M Assenmacher; Philippe Guillaume; Danila Valmori; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7634-40.
2001: Mikaël J Pittet; Daniel E Speiser; Danielle Liénard; Danila Valmori; Philippe Guillaume; Valérie Dutoit; Donata Rimoldi; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):796s-803s.
2001: Pedro Romero; Valérie Dutoit; Verena Rubio-Godoy; Danielle Liénard; Daniel Speiser; Philippe Guillaume; K Servis; Donata Rimoldi; Jean-Charles Cerottini; Danila Valmori
CD8+ T-cell response to NY-ESO-1: relative antigenicity and in vitro immunogenicity of natural and analogue sequences.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):766s-772s.
2001: Pierre-Yves Dietrich; Paul R Walker; Anne-Lise Quiquerez; Gaëlle Perrin; Valérie Dutoit; Danielle Liénard; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; Danila Valmori
Melanoma patients respond to a cytotoxic T lymphocyte-defined self-peptide with diverse and nonoverlapping T-cell receptor repertoires.
Cancer research 2001;61(5):2047-54.
2001: Daniel E Speiser; M Migliaccio; Mikaël J Pittet; Danila Valmori; Danielle Liénard; F Lejeune; Patrick Reichenbach; Philippe Guillaume; I Lüscher; Jean-Charles Cerottini; Pedro Romero
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
European journal of immunology 2001;31(2):459-66.
2001: Danila Valmori; Valérie Dutoit; Verena Rubio-Godoy; C Chambaz; Danielle Liénard; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Donata Rimoldi
Frequent cytolytic T-cell responses to peptide MAGE-A10(254-262) in melanoma.
Cancer research 2001;61(2):509-12.
2000: Ferdy J Lejeune; N Pujol; Danielle Liénard; François Mosimann; Wassim Raffoul; A Genton; L Guillou; M Landry; Pierre-Guy Chassot; René L Chiolero; Angelika Bischof Delaloye; Serge Leyvraz; R O Mirimanoff; D Bejkos; P F Leyvraz
Limb salvage by neoadjuvant isolated perfusion with TNFalpha and melphalan for non-resectable soft tissue sarcoma of the extremities.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2000;26(7):669-78.
2000: Danila Valmori; Valérie Dutoit; Danielle Liénard; Donata Rimoldi; Mikaël J Pittet; Patrick Champagne; Kim Ellefsen; U Sahin; Daniel Speiser; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.
Cancer research 2000;60(16):4499-506.
2000: Danila Valmori; Valérie Dutoit; Danielle Liénard; Ferdy Lejeune; Daniel Speiser; Donata Rimoldi; Vincenzo Cerundolo; Pierre-Yves Dietrich; Jean-Charles Cerottini; Pedro Romero
Tetramer-guided analysis of TCR beta-chain usage reveals a large repertoire of melan-A-specific CD8+ T cells in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):533-8.
2000: Danila Valmori; Frédéric Lévy; Isabelle Miconnet; Paul Zajac; Giulio C Spagnoli; Donata Rimoldi; Danielle Liénard; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
Induction of potent antitumor CTL responses by recombinant vaccinia encoding a melan-A peptide analogue.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):1125-31.
2000: P Romero; M J Pittet; D Valmori; Daniel E Speiser; V Cerundolo; Danielle Liénard; F Lejeune; J C Cerottini
Immune monitoring in cancer immunotherapy.
Ernst Schering Research Foundation workshop 2000;(30):75-97.
1999: Danila Valmori; Jean-François Fonteneau; Salvatore Valitutti; Nadine Gervois; R Dunbar; Danielle Liénard; Donata Rimoldi; Vincenzo Cerundolo; Francine Jotereau; Jean-Charles Cerottini; Daniel E Speiser; Pedro Romero
Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.
International immunology 1999;11(12):1971-80.
1999: Danielle Liénard; Alexander M M Eggermont; Heimen Schraffordt Koops; B Kroon; G Towse; S Hiemstra; P Schmitz; J Clarke; G Steinmann; F Rosenkaimer; Ferdy J Lejeune
Isolated limb perfusion with tumour necrosis factor-alpha and melphalan with or without interferon-gamma for the treatment of in-transit melanoma metastases: a multicentre randomized phase II study.
Melanoma research 1999;9(5):491-502.
1999: Daniel E Speiser; Mikaël J Pittet; Danila Valmori; R Dunbar; Donata Rimoldi; Danielle Liénard; H Robson MacDonald; Jean-Charles Cerottini; Vincenzo Cerundolo; Pedro Romero
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1999;190(6):775-82.
1999: Mikaël J Pittet; Danila Valmori; P R Dunbar; Daniel E Speiser; Danielle Liénard; Ferdy Lejeune; Katharina Fleischhauer; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
The Journal of experimental medicine 1999;190(5):705-15.
1999: Danila Valmori; Mikaël J Pittet; C Vonarbourg; Donata Rimoldi; Danielle Liénard; Daniel Speiser; R Dunbar; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
Cancer research 1999;59(16):4050-5.
1999: Daniel E Speiser; Danila Valmori; Donata Rimoldi; Mikaël J Pittet; Danielle Liénard; Vincenzo Cerundolo; H Robson MacDonald; Jean-Charles Cerottini; Pedro Romero
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
European journal of immunology 1999;29(6):1990-9.
1999: Danila Valmori; Mikaël J Pittet; Donata Rimoldi; Danielle Liénard; R Dunbar; Vincenzo Cerundolo; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
An antigen-targeted approach to adoptive transfer therapy of cancer.
Cancer research 1999;59(9):2167-73.
1999: AF Olieman; Danielle Liénard; Alexander M M Eggermont; Bin B R Kroon; Ferdy J Lejeune; Harald J Hoekstra; Heimen Schraffordt Koops
Hyperthermic isolated limb perfusion with tumor necrosis factor alpha, interferon gamma, and melphalan for locally advanced nonmelanoma skin tumors of the extremities: a multicenter study.
Archives of surgery (Chicago, Ill. : 1960) 1999;134(3):303-7.
1998: Danila Valmori; Nadine Gervois; Donata Rimoldi; Jean-François Fonteneau; Anilza Bonelo; Danielle Liénard; L Rivoltini; Francine Jotereau; Jean-Charles Cerottini; Pedro Romero
Diversity of the fine specificity displayed by HLA-A*0201-restricted CTL specific for the immunodominant Melan-A/MART-1 antigenic peptide.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6956-62.
1998: Pedro Romero; P R Dunbar; Danila Valmori; Mikaël J Pittet; G S Ogg; Donata Rimoldi; J L Chen; Danielle Liénard; Jean-Charles Cerottini; Vincenzo Cerundolo
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1998;188(9):1641-50.
1998: Ferdy J Lejeune; Curzio Rüegg; Danielle Liénard
Clinical applications of TNF-alpha in cancer.
Current opinion in immunology 1998;10(5):573-80.
1998: HS Schraffordt Koops; Alexander M M Eggermont; Danielle Liénard; Bin B R Kroon; Harald J Hoekstra; A N Van Geel; Omgo E Nieweg; Ferdy J Lejeune
Hyperthermic isolated limb perfusion for the treatment of soft tissue sarcomas.
Seminars in surgical oncology 1998;14(3):210-4.
1998: Danielle Liénard; A M Eggermont; B B Kroon; HS Schraffordt Koops; Ferdy J Lejeune
Isolated limb perfusion in primary and recurrent melanoma: indications and results.
Seminars in surgical oncology 1998;14(3):202-9.
1998: F Lejeune; Danielle Liénard; Alexander M M Eggermont
Regional administration of recombinant tumour necrosis factor-alpha in cancer, with special reference to melanoma.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 1998;9(3):211-8.
1998: Danila Valmori; Jean-François Fonteneau; C M Lizana; Nadine Gervois; Danielle Liénard; Donata Rimoldi; Victor Jongeneel; Francine Jotereau; Jean-Charles Cerottini; Pedro Romero
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):1750-8.
1997: J Gérain; Danielle Liénard; Sandro Pampallona; M Baumgartner; Curzio Rüegg; W A Buurman; Alexander M M Eggermont; F Lejeune
Systemic release of soluble TNF receptors after high-dose TNF in isolated limb perfusion.
Cytokine 1997;9(12):1034-42.
1997: Alexander M M Eggermont; HS Schraffordt Koops; J M Klausner; Danielle Liénard; B B Kroon; P M Schlag; G Ben-Ari; Ferdy J Lejeune
Isolation limb perfusion with tumor necrosis factor alpha and chemotherapy for advanced extremity soft tissue sarcomas.
Seminars in oncology 1997;24(5):547-55.
1997: Markus Furrer; Hans J Altermatt; Hans-Beat Ris; U Althaus; Curzio Rüegg; Danielle Liénard; Ferdy J Lejeune
Lack of antitumour activity of human recombinant tumour necrosis factor-alpha, alone or in combination with melphalan in a nude mouse human melanoma xenograft system.
Melanoma research 1997;7 Suppl 2():S43-9.
1997: G A Waanders; Donata Rimoldi; Danielle Liénard; S Carrel; Ferdy Lejeune; P Y Dietrich; Jean-Charles Cerottini; Pedro Romero
Melanoma-reactive human cytotoxic T lymphocytes derived from skin biopsies of delayed-type hypersensitivity reactions induced by injection of an autologous melanoma cell line.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):685-96.
1997: Danila Valmori; Danielle Liénard; G Waanders; Donata Rimoldi; Jean-Charles Cerottini; Pedro Romero
Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients.
Cancer research 1997;57(4):735-41.
1996: Alexander M M Eggermont; HS Schraffordt Koops; J M Klausner; Bin B R Kroon; P M Schlag; Danielle Liénard; Albertus N van Geel; Harald J Hoekstra; I Meller; Omgo E Nieweg; C Kettelhack; G Ben-Ari; J C Pector; Ferdy J Lejeune
Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience.
Annals of surgery 1996;224(6):756-64; discussion 764-5.
1996: Alexander M M Eggermont; HS Schraffordt Koops; Danielle Liénard; Bin B R Kroon; Albertus N van Geel; Harald J Hoekstra; Ferdy J Lejeune
Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(10):2653-65.
1995: S Schienk; Danielle Liénard; J Gerain; M Baumgartner; Ferdy J Lejeune; Ruth Chiquet-Ehrismann; Curzio Rüegg
Rapid increase in plasma tenascin-C concentration after isolated limb perfusion with high-dose tumor necrosis factor (TNF), interferon gamma (IFN gamma) and melphalan for regionally advanced tumors.
International journal of cancer. Journal international du cancer 1995;63(5):665-72.
1995: Ferdy J Lejeune; Danielle Liénard; Curzio Rüegg; S Leyvraz
Soft tissue sarcoma therapy: prospects for future studies.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1995;21(5):474-7.
1995: N Renard; P T Nooijen; Lia Schalkwijk; Robert M W de Waal; Alexander M M Eggermont; Danielle Liénard; B B Kroon; Ferdy J Lejeune; Dirk J Ruiter
VWF release and platelet aggregation in human melanoma after perfusion with TNF alpha.
The Journal of pathology 1995;176(3):279-87.
1995: F Lejeune; Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; F Rosenkaimer; J Gérain; Joost M Klaase; B Kroon; P Schmitz
[Efficacy of the tumor necrosis factor-alpha (rTNF-alpha) associated with interferon-gamma and chemotherapy in extracorporeal circulation in the limb in inoperable malignant melanoma, soft tissue sarcoma and epidermoid carcinoma. A 4-year experience].
Bulletin du cancer 1995;82(7):561-7.
1995: F Lejeune; Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; F Rosenkaimer; J Gérain; Joost M Klaase; B Kroon; J Vanderveken; P Schmitz
Administration of high-dose tumor necrosis factor alpha by isolation perfusion of the limbs. Rationale and results.
The Journal of infusional chemotherapy 1995;5(2):73-81.
1995: F Lejeune; Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; B Kroon
[Value of isolation-perfusion of the limbs in melanomas and sarcomas].
Annales de chirurgie 1995;49(1):9-12.
1995: Joost M Klaase; Bin B R Kroon; Alexander M M Eggermont; A N van Geel; HS Schraffordt Koops; J Oldhoff; Danielle Liénard; F J Lejeune; R Berkel; H R Franklin
A retrospective comparative study evaluating the results of mild hyperthermic versus controlled normothermic perfusion for recurrent melanoma of the extremities.
European journal of cancer (Oxford, England : 1990) 1995;31A(1):58-63.
1994: F Lejeune; Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; F Rosenkaimer; J Gérain; Joost M Klaase; B Kroon; J Vanderveken; P Schmitz
Rationale for using TNF alpha and chemotherapy in regional therapy of melanoma.
Journal of cellular biochemistry 1994;56(1):52-61.
1994: F Lejeune; Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; B Kroon; J Gérain; F Rosenkaimer; P Schmitz
Clinical experience with high-dose tumor necrosis factor alpha in regional therapy of advanced melanoma.
Circulatory shock 1994;43(4):191-7.
1994: N Renard; Danielle Liénard; Laurence Lespagnard; Alexander M M Eggermont; R Heimann; F Lejeune
Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNF alpha).
International journal of cancer. Journal international du cancer 1994;57(5):656-63.
1994: P Autier; Jean-François Doré; F Lejeune; K F Koelmel; O Geffeler; P Hille; J P Cesarini; Danielle Liénard; A Liabeuf; M Joarlette
Recreational exposure to sunlight and lack of information as risk factors for cutaneous malignant melanoma. Results of an European Organization for Research and Treatment of Cancer (EORTC) case-control study in Belgium, France and Germany. The EORTC Malignant Melanoma Cooperative Group.
Melanoma research 1994;4(2):79-85.
1994: Danielle Liénard; Alexander M M Eggermont; H Schraffordt Koops; B B Kroon; F Rosenkaimer; P Autier; Ferdy J Lejeune
Isolated perfusion of the limb with high-dose tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) and melphalan for melanoma stage III. Results of a multi-centre pilot study.
Melanoma research 1994;4 Suppl 1():21-6.
1992: J Gérain; Danielle Liénard; P Ewalenko; Ferdy J Lejeune
High serum levels of TNF-alpha after its administration for isolation perfusion of the limb.
Cytokine 1992;4(6):585-91.
1992: Danielle Liénard; Ferdy J Lejeune; P Ewalenko
In transit metastases of malignant melanoma treated by high dose rTNF alpha in combination with interferon-gamma and melphalan in isolation perfusion.
World journal of surgery 1992;16(2):234-40.
1991: P Autier; M Joarlette; F Lejeune; Danielle Liénard; J André; G Achten
Cutaneous malignant melanoma and exposure to sunlamps and sunbeds: a descriptive study in Belgium.
Melanoma research 1991;1(1):69-74.
1989: Ferdy J Lejeune; Danielle Liénard; M el Douaihy; J V Seyedi; P Ewalenko
Results of 206 isolated limb perfusions for malignant melanoma.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1989;15(6):510-9.
1988: Ferdy J Lejeune; Ghanem Ghanem; Danielle Liénard; P Ewalenko
An accurate method for cytostatic dosimetry in isolation perfusion based on limb vascular volume determination.
Antibiotics and chemotherapy 1988;40():63-76.