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Juris Liepnieks

Research Profile

Disorders

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Juris J Liepnieks; Lucy Q Zhang; Merrill D Benson
Progression of transthyretin amyloid neuropathy after liver transplantation.
Merrill D Benson; Jeffrey Breall; Oscar W Cummings; Juris J Liepnieks
Biochemical characterisation of amyloid by endomyocardial biopsy.
Merrill D Benson; Sam James; Katherine Scott; Juris J Liepnieks; Barbara Kluve-Beckerman
Leukocyte chemotactic factor 2: A novel renal amyloid protein.

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All Publications

2010: Juris J Liepnieks; Lucy Q Zhang; Merrill D Benson
Progression of transthyretin amyloid neuropathy after liver transplantation.
Neurology 2010;75(4):324-7.
2009: Merrill D Benson; Jeffrey Breall; Oscar W Cummings; Juris J Liepnieks
Biochemical characterisation of amyloid by endomyocardial biopsy.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2009;16(1):9-14.
2008: Merrill D Benson; Sam James; Katherine Scott; Juris J Liepnieks; Barbara Kluve-Beckerman
Leukocyte chemotactic factor 2: A novel renal amyloid protein.
Kidney international 2008;74(2):218-22.
2007: Ziad S Zaky; Juris J Liepnieks; Douglas K Rex; Oscar W Cummings; Merrill D Benson
Lambda II immunoglobulin light chain protein in primary localized rectal amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(4):299-304.
2007: Juris J Liepnieks; Merrill D Benson
Progression of cardiac amyloid deposition in hereditary transthyretin amyloidosis patients after liver transplantation.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(4):277-82.
2007: Louise C Serpell; Merrill Benson; Juris J Liepnieks; Paul E Fraser
Structural analyses of fibrinogen amyloid fibrils.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(3):199-203.
2007: Charles J Kahi; Saeed Vakili; Juris J Liepnieks; Merrill Benson
Amyloidoma of the esophagus.
The American journal of gastroenterology 2007;102(4):910-1.
2007: Nadine Magy; Merrill D Benson; Juris J Liepnieks; Barbara Kluve-Beckerman
Cellular events associated with the initial phase of AA amyloidogenesis: insights from a human monocyte model.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(1):51-63.
2006: Juris J Liepnieks; Donald L Wilson; Merrill D Benson
Biochemical characterization of vitreous and cardiac amyloid in Ile84Ser transthyretin amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2006;13(3):170-7.
2006: Donna Ray; Ailing Wu; John Wilkinson; Hedwig S Murphy; Qianjin Lu; Barbara Kluve-Beckerman; Juris J Liepnieks; Merrill Benson; Raymond L Yung; Bruce C Richardson
Aging in heterozygous Dnmt1-deficient mice: effects on survival, the DNA methylation genes, and the development of amyloidosis.
The journals of gerontology. Series A, Biological sciences and medical sciences 2006;61(2):115-24.
2004: Kamran Hamidi Asl; Juris J Liepnieks; William R Nunery; Masahide Yazaki; Merrill D Benson
Kappa III immunoglobulin light chain origin of localized orbital amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2004;11(3):179-83.
2004: Masahide Yazaki; Juris J Liepnieks; John Callaghan; Charles E Connolly; Merrill D Benson
Chemical characterization of a lambda I amyloid protein isolated from formalin-fixed and paraffin-embedded tissue sections.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2004;11(1):50-5.
2003: Nadine Magy; Juris J Liepnieks; Masahide Yazaki; Barbara Kluve-Beckerman; Merrill D Benson
Renal transplantation for apolipoprotein AII amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2003;10(4):224-8.
2003: Masahide Yazaki; Juris J Liepnieks; John C Kincaid; Merrill D Benson
Contribution of wild-type transthyretin to hereditary peripheral nerve amyloid.
Muscle & nerve 2003;28(4):438-42.
2003: S McKechnie; F Yang; Clive Harper; Martin McGee-Collett; C J A Henderson; Juris J Liepnieks; Masahide Yazaki; Merrill D Benson; J G McLeod
Amyloidoma of a spinal root.
Neurology 2003;61(6):834-6.
2003: Masahide Yazaki; Juris J Liepnieks; Mark S Barats; Arthur H Cohen; Merrill D Benson
Hereditary systemic amyloidosis associated with a new apolipoprotein AII stop codon mutation Stop78Arg.
Kidney international 2003;64(1):11-6.
2003: Nadine Magy; Juris J Liepnieks; Merrill D Benson; Barbara Kluve-Beckerman
Amyloid-enhancing factor mediates amyloid formation on fibroblasts via a nidus/template mechanism.
Arthritis and rheumatism 2003;48(5):1430-7.
2003: Nadine Magy; Juris J Liepnieks; Helder Gil; Bernadette Kantelip; Jean-Louis Dupond; Barbara Kluve-Beckerman; Merrill D Benson
A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2003;10(1):29-33.
2002: Barbara Kluve-Beckerman; John J Manaloor; Juris J Liepnieks
A pulse-chase study tracking the conversion of macrophage-endocytosed serum amyloid A into extracellular amyloid.
Arthritis and rheumatism 2002;46(7):1905-13.
2001: Masahide Yazaki; Juris J Liepnieks; Takeshi Yamashita; Brian D Guenther; Martha Skinner; Merrill D Benson
Renal amyloidosis caused by a novel stop-codon mutation in the apolipoprotein A-II gene.
Kidney international 2001;60(5):1658-65.
2001: Pedro Piccardo; Juris J Liepnieks; A William; Stephen R Dlouhy; Martin R Farlow; K Young; David Nochlin; Thomas D Bird; R R Nixon; Melvyn Ball; Charles DeCarli; Orso Bugiani; Fabrizio Tagliavini; M D Benson; Bernardino Ghetti
Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations.
The American journal of pathology 2001;158(6):2201-7.
2001: Barbara Kluve-Beckerman; J Manaloor; Juris J Liepnieks
Binding, trafficking and accumulation of serum amyloid A in peritoneal macrophages.
Scandinavian journal of immunology 2001;53(4):393-400.
2001: Merrill D Benson; Juris J Liepnieks; Masahide Yazaki; Takeshi Yamashita; Kamran Hamidi Asl; Brian D Guenther; Barbara Kluve-Beckerman
A new human hereditary amyloidosis: the result of a stop-codon mutation in the apolipoprotein AII gene.
Genomics 2001;72(3):272-7.
2001: Masahide Yazaki; Juris J Liepnieks; Jill R Murrell; Masaki Takao; Brian D Guenther; Pedro Piccardo; Martin R Farlow; Bernardino Ghetti; Merrill D Benson
Biochemical characterization of a neuroserpin variant associated with hereditary dementia.
The American journal of pathology 2001;158(1):227-33.
2000: J Orpiszewski; N Schormann; Barbara Kluve-Beckerman; Juris J Liepnieks; M D Benson
Protein aging hypothesis of Alzheimer disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(9):1255-63.
2000: Lishan Wang; Juris J Liepnieks; Merrill D Benson; Barbara Kluve-Beckerman
Expression of SAA and amyloidogenesis in congenic mice of CE/J and C57BL/6 strains.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2000;7(1):26-31.
1999: Barbara Kluve-Beckerman; Juris J Liepnieks; Lishan Wang; Merrill D Benson
A cell culture system for the study of amyloid pathogenesis. Amyloid formation by peritoneal macrophages cultured with recombinant serum amyloid A.
The American journal of pathology 1999;155(1):123-33.
1999: Kamran Hamidi Asl; Juris J Liepnieks; Masaaki Nakamura; Merrill D Benson
Organ-specific (localized) synthesis of Ig light chain amyloid.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(9):5556-60.
1999: Kamran Hamidi Asl; Juris J Liepnieks; Masaaki Nakamura; Frank Parker; Merrill D Benson
A novel apolipoprotein A-1 variant, Arg173Pro, associated with cardiac and cutaneous amyloidosis.
Biochemical and biophysical research communications 1999;257(2):584-8.
1999: L Hamidi Asl; Juris J Liepnieks; Kamran Hamidi Asl; T Uemichi; G Moulin; E Desjoyaux; R Loire; M Delpech; G Grateau; Merrill D Benson
Hereditary amyloid cardiomyopathy caused by a variant apolipoprotein A1.
The American journal of pathology 1999;154(1):221-7.
1998: T Uemichi; Juris J Liepnieks; M A Gertz; Merrill D Benson
Fibrinogen A alpha chain Leu 554: an African-American kindred with late onset renal amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(3):188-92.
1998: Kamran Hamidi Asl; Juris J Liepnieks; Richard Bihrle; Merrill D Benson
Local synthesis of amyloid fibril precursor in AL amyloidosis of the urinary tract.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(1):49-54.
1997: L Hamidi Asl; Juris J Liepnieks; T Uemichi; Jean-Michel Rebibou; Eve Justrabo; D Droz; Christiane Mousson; Jean-Marc Chalopin; Merrill D Benson; M Delpech; G Grateau
Renal amyloidosis with a frame shift mutation in fibrinogen aalpha-chain gene producing a novel amyloid protein.
Blood 1997;90(12):4799-805.
1997: T Uemichi; Juris J Liepnieks; Merrill D Benson
A trinucleotide deletion in the transthyretin gene (delta V 122) in a kindred with familial amyloidotic polyneuropathy.
Neurology 1997;48(6):1667-70.
1997: Barbara Kluve-Beckerman; Toshiyuki Yamada; Joyce Hardwick; Juris J Liepnieks; Merrill D Benson
Differential plasma clearance of murine acute-phase serum amyloid A proteins SAA1 and SAA2.
The Biochemical journal 1997;322 ( Pt 2)():663-9.
1996: T Uemichi; Juris J Liepnieks; F Alexander; Merrill D Benson
The molecular basis of renal amyloidosis in Irish-American and Polish-Canadian kindreds.
QJM : monthly journal of the Association of Physicians 1996;89(10):745-50.
1996: T Yamada; Juris J Liepnieks; Merrill D Benson; Barbara Kluve-Beckerman
Accelerated amyloid deposition in mice treated with the aspartic protease inhibitor, pepstatin.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):901-7.
1996: T Uemichi; Juris J Liepnieks; T Yamada; M A Gertz; Nils U Bang; Merrill D Benson
A frame shift mutation in the fibrinogen A alpha chain gene in a kindred with renal amyloidosis.
Blood 1996;87(10):4197-203.
1996: Merrill D Benson; Barbara Kluve-Beckerman; Juris J Liepnieks; J R Murrell; D Hanes; T Uemichi
Metabolism of amyloid proteins.
Ciba Foundation symposium 1996;199():104-13; discussion 113-8.
1995: N Schormann; J R Murrell; Juris J Liepnieks; Merrill D Benson
Tertiary structure of an amyloid immunoglobulin light chain protein: a proposed model for amyloid fibril formation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9490-4.
1995: T Yamada; Barbara Kluve-Beckerman; Juris J Liepnieks; Merrill D Benson
In vitro degradation of serum amyloid A by cathepsin D and other acid proteases: possible protection against amyloid fibril formation.
Scandinavian journal of immunology 1995;41(6):570-4.
1995: Juris J Liepnieks; Barbara Kluve-Beckerman; Merrill D Benson
Characterization of amyloid A protein in human secondary amyloidosis: the predominant deposition of serum amyloid A1.
Biochimica et biophysica acta 1995;1270(1):81-6.
1995: T Yamada; Juris J Liepnieks; Barbara Kluve-Beckerman; Merrill D Benson
Cathepsin B generates the most common form of amyloid A (76 residues) as a degradation product from serum amyloid A.
Scandinavian journal of immunology 1995;41(1):94-7.
1994: Rodolfo Berni; G Malpeli; Claudia Folli; J R Murrell; Juris J Liepnieks; M D Benson
The Ile-84-->Ser amino acid substitution in transthyretin interferes with the interaction with plasma retinol-binding protein.
The Journal of biological chemistry 1994;269(38):23395-8.
1994: T Yamada; Barbara Kluve-Beckerman; Juris J Liepnieks; Merrill D Benson
Fibril formation from recombinant human serum amyloid A.
Biochimica et biophysica acta 1994;1226(3):323-9.
1994: T Uemichi; Juris J Liepnieks; Merrill D Benson
Hereditary renal amyloidosis with a novel variant fibrinogen.
The Journal of clinical investigation 1994;93(2):731-6.
1994: HN Rosen; J R Murrell; Juris J Liepnieks; Merrill D Benson; V Cody; Alan C Moses
Threonine for alanine substitution at position 109 of transthyretin differentially alters human transthyretin's affinity for iodothyronines.
Endocrinology 1994;134(1):27-34.
1993: Juris J Liepnieks; Bernardino Ghetti; Martin R Farlow; Allen D Roses; Merrill D Benson
Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations.
Biochemical and biophysical research communications 1993;197(2):386-92.
1993: Barbara Kluve-Beckerman; M Song; Merrill D Benson; Juris J Liepnieks
Recombinant murine serum amyloid A from baculovirus-infected insect cells: purification and characterization.
Biochimica et biophysica acta 1993;1182(3):303-10.
1993: HN Rosen; Alan C Moses; J R Murrell; Juris J Liepnieks; Merrill D Benson
Thyroxine interactions with transthyretin: a comparison of 10 different naturally occurring human transthyretin variants.
The Journal of clinical endocrinology and metabolism 1993;77(2):370-4.
1993: Merrill D Benson; Juris J Liepnieks; T Uemichi; G Wheeler; R Correa
Hereditary renal amyloidosis associated with a mutant fibrinogen alpha-chain.
Nature genetics 1993;3(3):252-5.
1993: Rose S Fife; Barbara Kluve-Beckerman; D S Houser; C Proctor; Juris J Liepnieks; I Masuda; D J McCarty; Lawrence M Ryan
Evidence that a 550,000-dalton cartilage matrix glycoprotein is a chondrocyte membrane-associated protein closely related to ceruloplasmin.
The Journal of biological chemistry 1993;268(6):4407-11.
1993: J A Hamilton; LK Steinrauf; Bradford C Braden; Juris J Liepnieks; Merrill D Benson; Gösta Holmgren; Ola Sandgren; L Steen
The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution.
The Journal of biological chemistry 1993;268(4):2416-24.
1993: Merrill D Benson; J Julien; Juris J Liepnieks; S Zeldenrust; M D Benson
A transthyretin variant (alanine 49) associated with familial amyloidotic polyneuropathy in a French family.
Journal of medical genetics 1993;30(2):117-9.
1992: J R Murrell; R G Schoner; Juris J Liepnieks; HN Rosen; Alan C Moses; Merrill D Benson
Production and functional analysis of normal and variant recombinant human transthyretin proteins.
The Journal of biological chemistry 1992;267(23):16595-600.
1992: J A Hamilton; LK Steinrauf; Juris J Liepnieks; Merrill D Benson; Gösta Holmgren; Ola Sandgren; L Steen
Alteration in molecular structure which results in disease: the Met-30 variant of human plasma transthyretin.
Biochimica et biophysica acta 1992;1139(1-2):9-16.
1991: Juris J Liepnieks; F E Dwulet; Merrill D Benson; Barbara Kluve-Beckerman; I Kushner
The primary structure of serum amyloid A protein in the rabbit: comparison with serum amyloid A proteins in other species.
The Journal of laboratory and clinical medicine 1991;118(6):570-5.
1991: LK Steinrauf; Y J Cao; J Hamilton; J Murrell; Juris J Liepnieks; Merrill D Benson
Preparation and crystallization of human transthyretin (prealbumin) variants.
Biochemical and biophysical research communications 1991;179(2):804-9.
1991: W C Nichols; Juris J Liepnieks; E L Snyder; Merrill D Benson
Senile cardiac amyloidosis associated with homozygosity for a transthyretin variant (ILE-122).
The Journal of laboratory and clinical medicine 1991;117(3):175-80.
1990: Alan C Moses; HN Rosen; D E Moller; S Tsuzaki; J E Haddow; J Lawlor; Juris J Liepnieks; W C Nichols; Merrill D Benson
A point mutation in transthyretin increases affinity for thyroxine and produces euthyroid hyperthyroxinemia.
The Journal of clinical investigation 1990;86(6):2025-33.
1990: Juris J Liepnieks; F E Dwulet; Merrill D Benson
Amino acid sequence of a kappa I primary (AL) amyloid protein (AND).
Molecular immunology 1990;27(6):481-5.
1989: W C Nichols; Juris J Liepnieks; Victor A McKusick; Merrill D Benson
Direct sequencing of the gene for Maryland/German familial amyloidotic polyneuropathy type II and genotyping by allele-specific enzymatic amplification.
Genomics 1989;5(3):535-40.
1988: W C Nichols; F E Dwulet; Juris J Liepnieks; Merrill D Benson
Variant apolipoprotein AI as a major constituent of a human hereditary amyloid.
Biochemical and biophysical research communications 1988;156(2):762-8.