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Adrián Lifschitz

Research Profile

Chemicals & Drugs

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Sheep
Cattle

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Physiology

Drug Interactions

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Sheep Diseases

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Publications

TOP 3
M L Maté; Alexandra Muscher; Juan M Sallovitz; B Schröder; M Ballent; Carlos E Lanusse; Adrián L Lifschitz; M R Wilkens; Guillermo Virkel
Cytochrome P450 3A expression and function in liver and intestinal mucosa from dexamethasone-treated sheep.
M Lloberas; Guillermo Virkel; Luis Alvarez; C Entrocasso; Carlos E Lanusse; Adrián L Lifschitz
Measurement of ivermectin concentrations in target worms and host gastrointestinal tissues: influence of the route of administration on the activity against resistant Haemonchus contortus in lambs.
M Ballent; Adrián L Lifschitz; Laura Maté; Juan M Sallovitz; Guillermo Virkel; Carlos E Lanusse
In vivo and ex vivo assessment of the interaction between ivermectin and danofloxacin in sheep.

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2012: M L Maté; Alexandra Muscher; Juan M Sallovitz; B Schröder; M Ballent; Carlos E Lanusse; Adrián L Lifschitz; M R Wilkens; Guillermo Virkel
Cytochrome P450 3A expression and function in liver and intestinal mucosa from dexamethasone-treated sheep.
Journal of veterinary pharmacology and therapeutics 2012;35(4):319-28.
2012: M Lloberas; Guillermo Virkel; Luis Alvarez; C Entrocasso; Carlos E Lanusse; Adrián L Lifschitz
Measurement of ivermectin concentrations in target worms and host gastrointestinal tissues: influence of the route of administration on the activity against resistant Haemonchus contortus in lambs.
Experimental parasitology 2012;131(3):304-9.
2012: M Ballent; Adrián L Lifschitz; Laura Maté; Juan M Sallovitz; Guillermo Virkel; Carlos E Lanusse
In vivo and ex vivo assessment of the interaction between ivermectin and danofloxacin in sheep.
Veterinary journal (London, England : 1997) 2012;192(3):422-7.
2012: Adrián L Lifschitz; M Ballent; Carlos E Lanusse
Macrocyclic lactones and cellular transport-related drug interactions: a perspective from in vitro assays to nematode control in the field.
Current pharmaceutical biotechnology 2012;13(6):912-23.
2012: Juan M Sallovitz; Guillermo Virkel; Fernanda A Imperiale; Adrián L Lifschitz; P Nejamkin; Carlos E Lanusse
Comparative in vitro characterization of moxidectin and doramectin percutaneous absorption through bovine skin.
Journal of veterinary pharmacology and therapeutics 2012;35(2):184-92.
2011: Lucía E Iglesias; Luis A Fusé; Adrián L Lifschitz; Edgardo M Rodríguez; María F Sagüés; Carlos A Saumell
Environmental monitoring of ivermectin excreted in spring climatic conditions by treated cattle on dung fauna and degradation of faeces on pasture.
Parasitology research 2011;108(5):1185-91.
2010: Luis Alvarez; C Entrocasso; Adrián L Lifschitz; J Manazza; L Ceballos; B Borda; Carlos E Lanusse
Albendazole failure to control resistant nematodes in lambs: lack of effect of fasting-induced improvement on drug absorption.
The Journal of parasitology 2010;96(6):1204-10.
2010: L Maté; Guillermo Virkel; Adrián L Lifschitz; Juan M Sallovitz; M Ballent; Carlos E Lanusse
Phase 1 and phase 2 metabolic activities along the small intestine in adult male sheep.
Journal of veterinary pharmacology and therapeutics 2010;33(6):537-45.
2010: Adrián L Lifschitz; C Entrocasso; L Alvarez; M Lloberas; M Ballent; G Manazza; Guillermo Virkel; B Borda; C Lanusse
Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep.
Veterinary parasitology 2010;172(3-4):291-8.
2010: M Ballent; Adrián L Lifschitz; Guillermo Virkel; L Mate; Carlos E Lanusse
Pretreatment with the inducers rifampicin and phenobarbital alters ivermectin gastrointestinal disposition.
Journal of veterinary pharmacology and therapeutics 2010;33(3):252-9.
2010: L Moreno; L Ceballos; Adrián L Lifschitz; Mariana Bistoletti; Luis Alvarez; Carlos E Lanusse
Combined subcutaneous administration of ivermectin and nitroxynil in sheep: age/body weight related changes to the kinetic disposition of both compounds.
Research in veterinary science 2010;88(2):315-20.
2009: Fernanda A Imperiale; Juan M Sallovitz; C Farias; Adrián L Lifschitz; Carlos E Lanusse
Licking induced changes to the pattern of moxidectin milk elimination after topical treatment in dairy cows.
Journal of veterinary pharmacology and therapeutics 2009;32(6):534-40.
2009: Adrián L Lifschitz; Guillermo Virkel; M Ballent; Juan M Sallovitz; Carlos E Lanusse
Combined use of ivermectin and triclabendazole in sheep: in vitro and in vivo characterisation of their pharmacological interaction.
Veterinary journal (London, England : 1997) 2009;182(2):261-8.
2009: Víctor H Suárez; Adrián L Lifschitz; Juan M Sallovitz; Carlos E Lanusse
Effects of faecal residues of moxidectin and doramectin on the activity of arthropods in cattle dung.
Ecotoxicology and environmental safety 2009;72(5):1551-8.
2009: Fernanda A Imperiale; C Farias; Alejandra Pis; Juan M Sallovitz; Adrián L Lifschitz; Carlos E Lanusse
Thermal stability of antiparasitic macrocyclic lactones milk residues during industrial processing.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2009;26(1):57-62.
2008: Adrián L Lifschitz; S Nava; A A Guglielmone; Fernanda A Imperiale; C Farias; A J Mangold; Carlos E Lanusse
Failure of ivermectin and eprinomectin to control Amblyomma parvum in goats: characterization of acaricidal activity and drug pharmacokinetic disposition.
Veterinary parasitology 2008;156(3-4):284-92.
2008: Laura Maté; Guillermo Virkel; Adrián L Lifschitz; M Ballent; Carlos E Lanusse
Hepatic and extra-hepatic metabolic pathways involved in flubendazole biotransformation in sheep.
Biochemical pharmacology 2008;76(6):773-83.
2008: C Entrocasso; Luis Alvarez; J Manazza; Adrián L Lifschitz; B Borda; Guillermo Virkel; Lourdes Mottier; Carlos E Lanusse
Clinical efficacy assessment of the albendazole-ivermectin combination in lambs parasitized with resistant nematodes.
Veterinary parasitology 2008;155(3-4):249-56.
2008: Luis Alvarez; Adrián L Lifschitz; C Entrocasso; J Manazza; Lourdes Mottier; B Borda; Guillermo Virkel; Carlos E Lanusse
Evaluation of the interaction between ivermectin and albendazole following their combined use in lambs.
Journal of veterinary pharmacology and therapeutics 2008;31(3):230-9.
2007: Adrián L Lifschitz; Guillermo Virkel; M Ballent; Juan M Sallovitz; Fernanda A Imperiale; Alejandra Pis; Carlos E Lanusse
Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations.
Veterinary parasitology 2007;147(3-4):303-10.
2007: M Ballent; Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Carlos E Lanusse
Involvement of P-glycoprotein on ivermectin kinetic behaviour in sheep: itraconazole-mediated changes on gastrointestinal disposition.
Journal of veterinary pharmacology and therapeutics 2007;30(3):242-8.
2006: Adrián L Lifschitz; M Ballent; Guillermo Virkel; Juan M Sallovitz; Carlos E Lanusse
Sex-related differences in the gastrointestinal disposition of ivermectin in the rat: P-glycoprotein involvement and itraconazole modulation.
The Journal of pharmacy and pharmacology 2006;58(8):1055-62.
2006: Guillermo Virkel; Adrián L Lifschitz; Juan M Sallovitz; Alejandra Pis; Carlos E Lanusse
Assessment of the main metabolism pathways for the flukicidal compound triclabendazole in sheep.
Journal of veterinary pharmacology and therapeutics 2006;29(3):213-23.
2006: M Ballent; Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Carlos E Lanusse
Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: in vitro and in vivo assessments.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(3):457-63.
2005: Juan M Sallovitz; Adrián L Lifschitz; Fernanda A Imperiale; Guillermo Virkel; J Larghi; Carlos E Lanusse
Doramectin concentration profiles in the gastrointestinal tract of topically-treated calves: Influence of animal licking restriction.
Veterinary parasitology 2005;133(1):61-70.
2005: Adrián L Lifschitz; Guillermo Virkel; M Ballent; Juan M Sallovitz; Alejandra Pis; Carlos E Lanusse
Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents.
Journal of veterinary pharmacology and therapeutics 2005;28(5):411-8.
2004: Fernanda A Imperiale; Adrián L Lifschitz; Juan M Sallovitz; Guillermo Virkel; Carlos E Lanusse
Comparative depletion of ivermectin and moxidectin milk residues in dairy sheep after oral and subcutaneous administration.
The Journal of dairy research 2004;71(4):427-33.
2004: Guillermo Virkel; Adrián L Lifschitz; Juan M Sallovitz; Alejandra Pis; Carlos E Lanusse
Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(5):536-44.
2004: Guillermo Virkel; Adrián L Lifschitz; Juan M Sallovitz; G Inza; Carlos E Lanusse
Effect of the ionophore antibiotic monensin on the ruminal biotransformation of benzimidazole anthelmintics.
Veterinary journal (London, England : 1997) 2004;167(3):265-71.
2004: Adrián L Lifschitz; Juan M Sallovitz; Fernanda A Imperiale; Alejandra Pis; J Jauregui Lorda; Carlos E Lanusse
Pharmacokinetic evaluation of four ivermectin generic formulations in calves.
Veterinary parasitology 2004;119(2-3):247-57.
2004: Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Alejandra Pis; Fernanda A Imperiale; Carlos E Lanusse
Loperamide modifies the tissue disposition kinetics of ivermectin in rats.
The Journal of pharmacy and pharmacology 2004;56(1):61-7.
2004: MB Molento; Adrián L Lifschitz; Juan M Sallovitz; Carlos E Lanusse; Roger K Prichard
Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep.
Parasitology research 2004;92(2):121-7.
2003: Juan M Sallovitz; Adrián L Lifschitz; Fernanda A Imperiale; Guillermo Virkel; Carlos E Lanusse
A detailed assessment of the pattern of moxidectin tissue distribution after pour-on treatment in calves.
Journal of veterinary pharmacology and therapeutics 2003;26(6):397-404.
2003: Fernanda A Imperiale; Lourdes Mottier; Juan M Sallovitz; Adrián L Lifschitz; Carlos E Lanusse
Disposition of doramectin milk residues in lactating dairy sheep.
Journal of agricultural and food chemistry 2003;51(10):3185-90.
2003: Guillermo Virkel; Fernanda A Imperiale; Adrián L Lifschitz; Alejandra Pis; Ana Alvarez; Gracia Merino; Julio Prieto; Carlos E Lanusse
Effect of amphiphilic surfactant agents on the gastrointestinal absorption of albendazole in cattle.
Biopharmaceutics & drug disposition 2003;24(3):95-103.
2002: Fernanda A Imperiale; Juan M Sallovitz; Adrián L Lifschitz; Carlos E Lanusse
Determination of ivermectin and moxidecin residues in bovine milk and examination of the effects of these residues on acid fermentation of milk.
Food additives and contaminants 2002;19(9):810-8.
2002: Juan M Sallovitz; Adrián L Lifschitz; Fernanda A Imperiale; Alejandra Pis; Guillermo Virkel; Carlos E Lanusse
Breed differences on the plasma availability of moxidectin administered pour-on to calves.
Veterinary journal (London, England : 1997) 2002;164(1):47-53.
2002: Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Fernanda A Imperiale; Alejandra Pis; Carlos E Lanusse
Loperamide-induced enhancement of moxidectin availability in cattle.
Journal of veterinary pharmacology and therapeutics 2002;25(2):111-20.
2002: Guillermo Virkel; Adrián L Lifschitz; Alejandra Pis; Carlos E Lanusse
In vitro ruminal biotransformation of benzimidazole sulphoxide anthelmintics: enantioselective sulphoreduction in sheep and cattle.
Journal of veterinary pharmacology and therapeutics 2002;25(1):15-23.
2000: Adrián L Lifschitz; Fernanda A Imperiale; Guillermo Virkel; M Muñoz Cobeñas ; N Scherling; R DeLay; Carlos E Lanusse
Depletion of moxidectin tissue residues in sheep.
Journal of agricultural and food chemistry 2000;48(12):6011-5.
2000: Guillermo Virkel; Adrián L Lifschitz; AL Soraci; AS Sansinanea; Carlos E Lanusse
Enantioselective liver microsomal sulphoxidation of albendazole in cattle: effect of nutritional status.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(4):381-93.
2000: Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Jean-François Sutra; Pierre Galtier; Michel Alvinerie; Carlos E Lanusse
Comparative distribution of ivermectin and doramectin to parasite location tissues in cattle.
Veterinary parasitology 2000;87(4):327-38.
1999: Adrián L Lifschitz; Guillermo Virkel; Alejandra Pis; Fernanda A Imperiale; S Sanchez; Luis Alvarez; R Kujanek; Carlos E Lanusse
Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle.
Veterinary parasitology 1999;86(3):203-15.
1999: Adrián L Lifschitz; Guillermo Virkel; Fernanda A Imperiale; Jean-François Sutra; Pierre Galtier; Carlos E Lanusse; Michel Alvinerie
Moxidectin in cattle: correlation between plasma and target tissues disposition.
Journal of veterinary pharmacology and therapeutics 1999;22(4):266-73.
1999: Adrián L Lifschitz; Alejandra Pis; Luis Alvarez; Guillermo Virkel; S Sanchez; Juan M Sallovitz; R Kujanek; Carlos E Lanusse
Bioequivalence of ivermectin formulations in pigs and cattle.
Journal of veterinary pharmacology and therapeutics 1999;22(1):27-34.
1999: Michel Alvinerie; Jean-François Sutra; Pierre Galtier; Adrián L Lifschitz; Guillermo Virkel; Juan M Sallovitz; Carlos E Lanusse
Persistence of ivermectin in plasma and faeces following administration of a sustained-release bolus to cattle.
Research in veterinary science 1999;66(1):57-61.
1999: Guillermo Virkel; Adrián L Lifschitz; Alejandra Pis; Carlos E Lanusse
Influence of diet on the pattern of gastrointestinal biotransformation of netobimin and albendazole sulphoxide in sheep.
European journal of drug metabolism and pharmacokinetics 1999;24(1):31-7.
1998: Carlos E Lanusse; Guillermo Virkel; S F Sanchez; Luis I Alvarez; Adrián L Lifschitz; Fernanda A Imperiale; A Monfrinotti
Ricobendazole kinetics and availability following subcutaneous administration of a novel injectable formulation to calves.
Research in veterinary science 1998;65(1):5-10.
1997: Carlos E Lanusse; Adrián L Lifschitz; Guillermo Virkel; Luis Alvarez; S Sánchez; Jean-François Sutra; Pierre Galtier; Michel Alvinerie
Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle.
Journal of veterinary pharmacology and therapeutics 1997;20(2):91-9.
1997: Adrián L Lifschitz; Guillermo Virkel; M Mastromarino; Carlos E Lanusse
Enhanced plasma availability of the metabolites of albendazole in fasted adult sheep.
Veterinary research communications 1997;21(3):201-11.