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David Lightner

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TOP 3
Antony F McDonagh; Stefan E Boiadjiev; David A Lightner
Slipping past UGT1A1 and multidrug resistance-associated protein 2 in the liver: effects of steric compression and hydrogen bonding on the hepatobiliary elimination of synthetic bilirubins.
Sanjeev K Dey; David A Lightner
Toward an amphiphilic bilirubin: the crystal structure of a bilirubin e-isomer.
Sanjeev K Dey; David A Lightner
1,1'-bipyrroles: synthesis and stereochemistry.

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All Publications

2008: Antony F McDonagh; Stefan E Boiadjiev; David A Lightner
Slipping past UGT1A1 and multidrug resistance-associated protein 2 in the liver: effects of steric compression and hydrogen bonding on the hepatobiliary elimination of synthetic bilirubins.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(5):930-6.
2008: Sanjeev K Dey; David A Lightner
Toward an amphiphilic bilirubin: the crystal structure of a bilirubin e-isomer.
The Journal of organic chemistry 2008;73(7):2704-14.
2007: Sanjeev K Dey; David A Lightner
1,1'-bipyrroles: synthesis and stereochemistry.
The Journal of organic chemistry 2007;72(24):9395-7.
2007: Antony F McDonagh; David A Lightner
Influence of conformation and intramolecular hydrogen bonding on the acyl glucuronidation and biliary excretion of acetylenic bis-dipyrrinones related to bilirubin.
Journal of medicinal chemistry 2007;50(3):480-8.
2005: Zachary R Woydziak; Stefan E Boiadjiev; Wilma S Norona; Antony F McDonagh; David A Lightner
Synthesis and hepatic transport of strongly fluorescent cholephilic dipyrrinones.
The Journal of organic chemistry 2005;70(21):8417-23.
2005: Stefan E Boiadjiev; David A Lightner
Exciton chirality in trans-1,2-diamidocyclohexanes: fluorescent chromophores.
Chirality 2005;17(6):316-22.
2005: Stefan E Boiadjiev; David A Lightner
Readily synthesized novel fluorescent dipyrrinones.
The Journal of organic chemistry 2005;70(2):688-91.
2004: Stefan E Boiadjiev; Kimberly Watters; Steven Wolf; Bryon N Lai; William H Welch; Antony F McDonagh; David A Lightner
pKa and aggregation of bilirubin: titrimetric and ultracentrifugation studies on water-soluble pegylated conjugates of bilirubin and fatty acids.
Biochemistry 2004;43(49):15617-32.
2004: David K Stevenson; Ronald J Wong; Hendrik J Vreman; Antony F McDonagh; M Jeffrey Maisels; David A Lightner
NICHD Conference on Kernicterus: Research on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: Bench-to-Bedside--Diagnostic Methods and Prevention and Treatment Strategies.
Journal of perinatology : official journal of the California Perinatal Association 2004;24(8):521-5.
2003: Bin Tu; Brahmananda Ghosh; David A Lightner
A new class of linear tetrapyrroles: acetylenic 10,10a-didehydro-10a-homobilirubins.
The Journal of organic chemistry 2003;68(23):8950-63.
2003: Stefan E Boiadjiev; David A Lightner
Novel benzoic acid congeners of bilirubin.
The Journal of organic chemistry 2003;68(20):7591-604.
2003: Theodore G Pavlopoulos; David A Lightner; Justin O Brower
Laser action from two dipyrrinone dyes under flash-lamp pumping.
Applied optics 2003;42(18):3555-7.
2002: Antony F McDonagh; David A Lightner; Stefan E Boiadjiev; Justin O Brower; Wilma S Norona
Hepatobiliary excretion of dipyrrinone sulfonates in Mrp2-deficient (TR(-)) rats.
Bioorganic & medicinal chemistry letters 2002;12(17):2483-6.
2002: Antony F McDonagh; David A Lightner; Ari K Kar; Wilma S Norona
Hepatobiliary excretion of biliverdin isomers and C10-substituted biliverdins in Mrp2-deficient (TR(-)) rats.
Biochemical and biophysical research communications 2002;293(3):1077-83.
2002: Justin O Brower; David A Lightner
Synthesis and spectroscopic properties of a new class of strongly fluorescent dipyrrinones.
The Journal of organic chemistry 2002;67(8):2713-6.
2001: M T Huggins; David A Lightner
A C-H...O=C hydrogen bond? Intramolecular hydrogen bonding in a novel semirubin.
The Journal of organic chemistry 2001;66(25):8402-10.
2001: David A Lightner; Antony F McDonagh
Structure and metabolism of natural and synthetic bilirubins.
Journal of perinatology : official journal of the California Perinatal Association 2001;21 Suppl 1():S13-6; discussion S35-9.
2001: Antony F McDonagh; David A Lightner; D F Nogales; Wilma S Norona
Biliary excretion of a stretched bilirubin in UGT1A1-deficient (Gunn) and Mrp2-deficient (TR-) rats.
FEBS letters 2001;506(3):211-5.
2001: Stefan E Boiadjiev; David A Lightner
Chirality inversion in the bilirubin molecular exciton.
Chirality 2001;13(5):251-7.
2001: A K Tipton; David A Lightner; Antony F McDonagh
Synthesis and metabolism of the first thia-bilirubin.
The Journal of organic chemistry 2001;66(5):1832-8.
2000: M T Huggins; David A Lightner
Semirubin. A novel dipyrrinone strapped by intramolecular hydrogen bonds.
The Journal of organic chemistry 2000;65(19):6001-8.
2000: O Cunningham; Aisling Dunne; P Sabido; David A Lightner; Timothy J Mantle
Studies on the specificity of the tetrapyrrole substrate for human biliverdin-IXalpha reductase and biliverdin-IXbeta reductase. Structure-activity relationships define models for both active sites.
The Journal of biological chemistry 2000;275(25):19009-17.
2000: Stefan E Boiadjiev; David A Lightner
Relative steric size of SCH(3), OCH(3), and CH(3) groups from circular dichroism measurements.
Chirality 2000;12(4):204-15.
1997: F R Trull; Stefan E Boiadjiev; David A Lightner; Antony F McDonagh
Aqueous dissociation constants of bile pigments and sparingly soluble carboxylic acids by 13C NMR in aqueous dimethyl sulfoxide: effects of hydrogen bonding.
Journal of lipid research 1997;38(6):1178-88.
1997: S Salamí; Adela Mazo; David A Lightner; F R Trull
Synthesis of water-soluble bile pigments bound to amine-ended monomethoxypolyethyleneglycol: thiol addition and attempted enzymatic reduction of a bilindione derivative.
Cellular and molecular life sciences : CMLS 1997;53(3):248-6.
1997: Stefan E Boiadjiev; David A Lightner
Exciton chirality of bilirubin homologs.
Chirality 1997;9(5-6):604-15.
1996: David A Lightner; D L Holmes; A F McDonagh
Dissociation constants of water-insoluble carboxylic acids by 13C-NMR. pK(a)s of mesobiliverdin-XIII alpha and mesobilirubin-XIII alpha.
Experientia 1996;52(6):639-42.
1996: David A Lightner; D L Holmes; A F McDonagh
On the acid dissociation constants of bilirubin and biliverdin. pKa values from 13C NMR spectroscopy.
The Journal of biological chemistry 1996;271(5):2397-405.
1995: J Claret; O Ibars; K Lang; F R Trull; David A Lightner
Electrochemical reduction of the biliverdin-serum albumin complex as monitored by absorption and circular dichroism spectroscopy.
Biochimica et biophysica acta 1995;1243(2):221-9.
1995: D Nogales; David A Lightner
On the structure of bilirubin in solution. 13C[1H] heteronuclear Overhauser effect NMR analyses in aqueous buffer and organic solvents.
The Journal of biological chemistry 1995;270(1):73-7.
1992: F R Trull; O Ibars; David A Lightner
Conformation inversion of bilirubin formed by reduction of the biliverdin-human serum albumin complex: evidence from circular dichroism.
Archives of biochemistry and biophysics 1992;298(2):710-4.
1992: A F McDonagh; Y M Pu; David A Lightner
Effect of volatile anesthetics on the circular dichroism of bilirubin bound to human serum albumin.
Experientia 1992;48(3):246-8.
1988: David A Lightner; J Y An; Y M Pu
Circular dichroism of bilirubin-amine association complexes: insights into bilirubin-albumin binding.
Archives of biochemistry and biophysics 1988;262(2):543-59.