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Rachel Lill

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Ursula Schell; Stephen F Haydock; Andrew L Kaja; Isabelle Carletti; Rachel E Lill; Eliot Read; Lesley S Sheehan; Lindsey Low; Maria-Jose Fernandez; Friederike Grolle; Hamish A I McArthur; Rose M Sheridan; Peter F Leadlay; Barrie Wilkinson; Sabine Gaisser
Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
Lesley S Sheehan; Rachel E Lill; Barrie Wilkinson; Rose M Sheridan; William A Vousden; Andrew L Kaja; Gary D Crouse; James Gifford; Paul R Graupner; Laura Karr; Paul Lewer; Thomas C Sparks; Peter F Leadlay; Clive Waldron; Christine J Martin
Engineering of the spinosyn PKS: directing starter unit incorporation.
Matthew A Gregory; Hui Hong; Rachel E Lill; Sabine Gaisser; Hrvoje Petkovic; Lindsey Low; Lesley S Sheehan; Isabelle Carletti; Sarah J Ready; Michael J Ward; Andrew L Kaja; Alison J Weston; Iain R Challis; Peter F Leadlay; Christine J Martin; Barrie Wilkinson; Rose M Sheridan
Rapamycin biosynthesis: Elucidation of gene product function.

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All Publications

2008: Ursula Schell; Stephen F Haydock; Andrew L Kaja; Isabelle Carletti; Rachel E Lill; Eliot Read; Lesley S Sheehan; Lindsey Low; Maria-Jose Fernandez; Friederike Grolle; Hamish A I McArthur; Rose M Sheridan; Peter F Leadlay; Barrie Wilkinson; Sabine Gaisser
Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
Organic & biomolecular chemistry 2008;6(18):3315-27.
2006: Lesley S Sheehan; Rachel E Lill; Barrie Wilkinson; Rose M Sheridan; William A Vousden; Andrew L Kaja; Gary D Crouse; James Gifford; Paul R Graupner; Laura Karr; Paul Lewer; Thomas C Sparks; Peter F Leadlay; Clive Waldron; Christine J Martin
Engineering of the spinosyn PKS: directing starter unit incorporation.
Journal of natural products 2006;69(12):1702-10.
2006: Matthew A Gregory; Hui Hong; Rachel E Lill; Sabine Gaisser; Hrvoje Petkovic; Lindsey Low; Lesley S Sheehan; Isabelle Carletti; Sarah J Ready; Michael J Ward; Andrew L Kaja; Alison J Weston; Iain R Challis; Peter F Leadlay; Christine J Martin; Barrie Wilkinson; Rose M Sheridan
Rapamycin biosynthesis: Elucidation of gene product function.
Organic & biomolecular chemistry 2006;4(19):3565-8.
2005: Matthew A Gregory; Hrvoje Petkovic; Rachel E Lill; Steven J Moss; Barrie Wilkinson; Sabine Gaisser; Peter F Leadlay; Rose M Sheridan
Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.
Angewandte Chemie (International ed. in English) 2005;44(30):4757-60.
2004: Matthew A Gregory; Sabine Gaisser; Rachel E Lill; Hui Hong; Rose M Sheridan; Barrie Wilkinson; Hrvoje Petkovic; Alison J Weston; Isabelle Carletti; Huai-Lo Lee; James Staunton; Peter F Leadlay
Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.
Angewandte Chemie (International ed. in English) 2004;43(19):2551-3.
2003: Sabine Gaisser; Laurenz Kellenberger; Andrew L Kaja; Alison J Weston; Rachel E Lill; Gabriele Wirtz; Steven G Kendrew; Lindsey Low; Rose M Sheridan; Barrie Wilkinson; Ian S Galloway; Kim J Stutzman-Engwall; Hamish McArthur; James Staunton; Peter F Leadlay
Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272.
Organic & biomolecular chemistry 2003;1(16):2840-7.
2003: Francesca Del Vecchio; Hrvoje Petkovic; Steven G Kendrew; Lindsey Low; Barrie Wilkinson; Rachel E Lill; Jesús Cortés; Brian A M Rudd; James Staunton; Peter F Leadlay
Active-site residue, domain and module swaps in modular polyketide synthases.
Journal of industrial microbiology & biotechnology 2003;30(8):489-94.
2003: Hrvoje Petkovic; Rachel E Lill; Rose M Sheridan; Barrie Wilkinson; Ellen McCormick; Hamish McArthur; James Staunton; Peter F Leadlay; Steven G Kendrew
A novel erythromycin, 6-desmethyl erythromycin D, made by substituting an acyltransferase domain of the erythromycin polyketide synthase.
The Journal of antibiotics 2003;56(6):543-51.
2002: Sabine Gaisser; Rachel E Lill; James Staunton; Carmen Méndez; José Salas; Peter F Leadlay
Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea.
Molecular microbiology 2002;44(3):771-81.
2002: Sabine Gaisser; Christine J Martin; Barrie Wilkinson; Rose M Sheridan; Rachel E Lill; Alison J Weston; Sarah J Ready; Clive Waldron; Gary D Crouse; Peter F Leadlay; James Staunton
Engineered biosynthesis of novel spinosyns bearing altered deoxyhexose substituents.
Chemical communications (Cambridge, England) 2002;(6):618-9.
2001: Sabine Gaisser; Rachel E Lill; Gabriele Wirtz; F Grolle; James Staunton; Peter F Leadlay
New erythromycin derivatives from Saccharopolyspora erythraea using sugar O-methyltransferases from the spinosyn biosynthetic gene cluster.
Molecular microbiology 2001;41(5):1223-31.