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Roger Barker

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Williams-Gray Caroline H; Evans Jonathan R; Goris An; Foltynie Thomas; Ban Maria; Robbins Trevor W; Brayne Carol; Kolachana Bhaskar S; Weinberger Daniel R; Sawcer Stephen J; Barker Roger A
The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort.
O'Keeffe Gráinne C; Michell Andrew W; Barker Roger A
Biomarkers in Huntington's and Parkinson's Disease.
Barker Roger A; Michell Andrew W
"The eyes have it". Saccadometry and Parkinson's disease.

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All Publications

2009: Williams-Gray Caroline H; Evans Jonathan R; Goris An; Foltynie Thomas; Ban Maria; Robbins Trevor W; Brayne Carol; Kolachana Bhaskar S; Weinberger Daniel R; Sawcer Stephen J; Barker Roger A
The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort.
Brain : a journal of neurology 2009;132(Pt 11):2958-69.
2009: O'Keeffe Gráinne C; Michell Andrew W; Barker Roger A
Biomarkers in Huntington's and Parkinson's Disease.
Annals of the New York Academy of Sciences 2009;1180():97-110.
2009: Barker Roger A; Michell Andrew W
"The eyes have it". Saccadometry and Parkinson's disease.
Experimental neurology 2009;219(2):382-4.
2009: Hobbs Nicola Z; Henley Susie M D; Wild Edward J; Leung Kelvin K; Frost Chris; Barker Roger A; Scahill Rachael I; Barnes Josephine; Tabrizi Sarah J; Fox Nick C
Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease.
NeuroImage 2009;47(4):1659-65.
2009: O'Keeffe Gráinne C; Barker Roger A; Caldwell Maeve A
Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain.
Cell cycle (Georgetown, Tex.) 2009;8(18):2888-94.
2009: Clelland C D; Choi M; Romberg C; Clemenson G D; Fragniere A; Tyers P; Jessberger S; Saksida L M; Barker R A; Gage F H; Bussey T J
A functional role for adult hippocampal neurogenesis in spatial pattern separation.
Science (New York, N.Y.) 2009;325(5937):210-3.
2009: Wijeyekoon Ruwani; Barker Roger A
Cell replacement therapy for Parkinson's disease.
Biochimica et biophysica acta 2009;1792(7):688-702.
2009: Mason Sarah L; Barker Roger A
Emerging drug therapies in Huntington's disease.
Expert opinion on emerging drugs 2009;14(2):273-97.
2009: Lewis Simon J G; Barker Roger A
A pathophysiological model of freezing of gait in Parkinson's disease.
Parkinsonism & related disorders 2009;15(5):333-8.
2009: O'Keeffe Gráinne C; Tyers Pam; Aarsland Dag; Dalley Jeffrey W; Barker Roger A; Caldwell Maeve A
Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(21):8754-9.
2009: Lewis Simon J G; Barker Roger A
Understanding the dopaminergic deficits in Parkinson's disease: insights into disease heterogeneity.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2009;16(5):620-5.
2009: Henley Susie M D; Wild Edward J; Hobbs Nicola Z; Frost Chris; MacManus David G; Barker Roger A; Fox Nick C; Tabrizi Sarah J
Whole-brain atrophy as a measure of progression in premanifest and early Huntington's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(6):932-6.
2009: Williams-Gray Caroline H; Goris An; Saiki Misuzu; Foltynie Thomas; Compston D Alastair S; Sawcer Stephen J; Barker Roger A
Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson's disease.
Journal of neurology 2009;256(3):493-8.
2009: Thomas Meghan; Tyers Pam; Lazic Stanley E; Barker Roger A; Beazley Lyn; Ziman Mel
Graft outcomes influenced by co-expression of Pax7 in graft and host tissue.
Journal of anatomy 2009;214(3):396-405.
2009: Kehagia Angie A; Cools Roshan; Barker Roger A; Robbins Trevor W
Switching between abstract rules reflects disease severity but not dopaminergic status in Parkinson's disease.
Neuropsychologia 2009;47(4):1117-27.
2009: Ho Aileen K; Gilbert Abigail S; Mason Sarah L; Goodman Anna O; Barker Roger A
Health-related quality of life in Huntington's disease: Which factors matter most?
Movement disorders : official journal of the Movement Disorder Society 2009;24(4):574-8.
2009: Henley Susie M D; Wild Edward J; Hobbs Nicola Z; Scahill Rachael I; Ridgway Gerard R; Macmanus David G; Barker Roger A; Fox Nick C; Tabrizi Sarah J
Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease.
Journal of neurology 2009;256(2):203-12.
2009: Foltynie T; Cheeran B; Williams-Gray C H; Edwards M J; Schneider S A; Weinberger D; Rothwell J C; Barker R A; Bhatia K P
BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2009;80(2):141-4.
2009: Williams-Gray Caroline; Goris An; Foltynie Thomas; Compston Alastair; Sawcer Stephen; Barker Roger A
No evidence for association between an MAOA functional polymorphism and susceptibility to Parkinson's disease.
Journal of neurology 2009;256(1):132-3.
2009: Lazic Stanley E; Mason Sarah L; Michell Andrew W; Barker Roger A
Visualising disease progression on multiple variables with vector plots and path plots.
BMC medical research methodology 2009;9():32.
2009: Phillips Wendy; Michell Andrew; Pruess Harald; Barker Roger A
Animal models of neurodegenerative diseases.
Methods in molecular biology (Clifton, N.J.) 2009;549():137-55.
2008: Antoniades Chrystalina A; Barker Roger A
The search for biomarkers in Parkinson's disease: a critical review.
Expert review of neurotherapeutics 2008;8(12):1841-52.
2008: Mercy L; Hodges J R; Dawson K; Barker R A; Brayne C
Incidence of early-onset dementias in Cambridgeshire, United Kingdom.
Neurology 2008;71(19):1496-9.
2008: Politis Marios; Pavese Nicola; Tai Yen F; Tabrizi Sarah J; Barker Roger A; Piccini Paola
Hypothalamic involvement in Huntington's disease: an in vivo PET study.
Brain : a journal of neurology 2008;131(Pt 11):2860-9.
2008: Phillips Wendy; Shannon Kathleen M; Barker Roger A
The current clinical management of Huntington's disease.
Movement disorders : official journal of the Movement Disorder Society 2008;23(11):1491-504.
2008: Rowe J B; Hughes L; Ghosh B C P; Eckstein D; Williams-Gray C H; Fallon S; Barker R A; Owen A M
Parkinson's disease and dopaminergic therapy--differential effects on movement, reward and cognition.
Brain : a journal of neurology 2008;131(Pt 8):2094-105.
2008: Michell A W; Goodman A O G; Silva A H D; Lazic S E; Morton A J; Barker R A
Hand tapping: a simple, reproducible, objective marker of motor dysfunction in Huntington's disease.
Journal of neurology 2008;255(8):1145-52.
2008: Reuter I; Tai Y F; Pavese N; Chaudhuri K R; Mason S; Polkey C E; Clough C; Brooks D J; Barker R A; Piccini P
Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.
Journal of neurology, neurosurgery, and psychiatry 2008;79(8):948-51.
2008: Blackwell Andrew D; Paterson Nicole S; Barker Roger A; Robbins Trevor W; Sahakian Barbara J
The effects of modafinil on mood and cognition in Huntington's disease.
Psychopharmacology 2008;199(1):29-36.
2008: Quinn N; Barker R A; Wenning G K
Are trials of intravascular infusions of autologous mesenchymal stem cells in patients with multiple system atrophy currently justified, and are they effective?
Clinical pharmacology and therapeutics 2008;83(5):663-5.
2008: Wood Nigel I; Goodman Anna O G; van der Burg Jorien M M; Gazeau Véronique; Brundin Patrik; Björkqvist Maria; Petersén Asa; Tabrizi Sarah J; Barker Roger A; Morton A Jennifer
Increased thirst and drinking in Huntington's disease and the R6/2 mouse.
Brain research bulletin 2008;76(1-2):70-9.
2008: Wedderburn C; Wear H; Brown J; Mason S J; Barker R A; Hodges J; Williams-Gray C
The utility of the Cambridge Behavioural Inventory in neurodegenerative disease.
Journal of neurology, neurosurgery, and psychiatry 2008;79(5):500-3.
2008: Evans Jonathan R; Barker Roger A
Neurotrophic factors as a therapeutic target for Parkinson's disease.
Expert opinion on therapeutic targets 2008;12(4):437-47.
2008: Goodman Anna O G; Murgatroyd Peter R; Medina-Gomez Gema; Wood Nigel I; Finer Nicholas; Vidal-Puig Antonio J; Morton A Jennifer; Barker Roger A
The metabolic profile of early Huntington's disease--a combined human and transgenic mouse study.
Experimental neurology 2008;210(2):691-8.
2008: Kuan Wei-Li; Zhao Jing-Wei; Barker Roger A
The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.
Psychopharmacology 2008;197(2):279-93.
2008: Thompson S A; Calvin J; Hogg S; Ferdinandusse S; Wanders R J A; Barker R A
Relapsing encephalopathy in a patient with alpha-methylacyl-CoA racemase deficiency.
Journal of neurology, neurosurgery, and psychiatry 2008;79(4):448-50.
2008: Williams-Gray Caroline H; Hampshire Adam; Barker Roger A; Owen Adrian M
Attentional control in Parkinson's disease is dependent on COMT val 158 met genotype.
Brain : a journal of neurology 2008;131(Pt 2):397-408.
2008: Laguna Goya R; Tyers P; Barker R A
The search for a curative cell therapy in Parkinson's disease.
Journal of the neurological sciences 2008;265(1-2):32-42.
2008: Henley Susie M D; Wild Edward J; Hobbs Nicola Z; Warren Jason D; Frost Chris; Scahill Rachael I; Ridgway Gerard R; MacManus David G; Barker Roger A; Fox Nick C; Tabrizi Sarah J
Defective emotion recognition in early HD is neuropsychologically and anatomically generic.
Neuropsychologia 2008;46(8):2152-60.
2008: Clelland Claire D; Barker Roger A; Watts Colin
Cell therapy in Huntington disease.
Neurosurgical focus 2008;24(3-4):E9.
2007: Lawrence Andrew J; Blackwell Andrew D; Barker Roger A; Spagnolo Francesca; Clark Luke; Aitken Michael R F; Sahakian Barbara J
Predictors of punding in Parkinson's disease: results from a questionnaire survey.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2339-45.
2007: Goya Rocio Laguna; Kuan Wei-Li; Barker Roger A
The future of cell therapies in the treatment of Parkinson's disease.
Expert opinion on biological therapy 2007;7(10):1487-98.
2007: Wright Ben L C; Barker Roger A
Established and emerging therapies for Huntington's disease.
Current molecular medicine 2007;7(6):579-87.
2007: Goris An; Williams-Gray Caroline H; Clark Graeme R; Foltynie Thomas; Lewis Simon J G; Brown Joanne; Ban Maria; Spillantini Maria G; Compston Alastair; Burn David J; Chinnery Patrick F; Barker Roger A; Sawcer Stephen J
Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease.
Annals of neurology 2007;62(2):145-53.
2007: Antoniades Chrystalina A; Altham Pat M E; Mason Sarah L; Barker Roger A; Carpenter Roger
Saccadometry: a new tool for evaluating presymptomatic Huntington patients.
Neuroreport 2007;18(11):1133-6.
2007: Williams-Gray C H; Foltynie T; Brayne C E G; Robbins T W; Barker R A
Evolution of cognitive dysfunction in an incident Parkinson's disease cohort.
Brain : a journal of neurology 2007;130(Pt 7):1787-98.
2007: Goris A; Williams-Gray C H; Foltynie T; Brown J; Maranian M; Walton A; Compston D A S; Barker R A; Sawcer S J
Investigation of TGFB2 as a candidate gene in multiple sclerosis and Parkinson's disease.
Journal of neurology 2007;254(7):846-8.
2007: Tai Yen F; Pavese Nicola; Gerhard Alexander; Tabrizi Sarah J; Barker Roger A; Brooks David J; Piccini Paola
Microglial activation in presymptomatic Huntington's disease gene carriers.
Brain : a journal of neurology 2007;130(Pt 7):1759-66.
2007: Lazic Stanley E; Goodman Anna O G; Grote Helen E; Blakemore Colin; Morton A Jennifer; Hannan Anthony J; van Dellen Anton; Barker Roger A
Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients.
Brain research 2007;1151():219-26.
2007: Williams-Gray Caroline H; Hampshire Adam; Robbins Trevor W; Owen Adrian M; Barker Roger A
Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(18):4832-8.
2007: Williams-Gray Caroline H; Barker Roger A
Visual hallucinations predict increased benefits from rivastigmine in Parkinson's disease dementia.
Nature clinical practice. Neurology 2007;3(5):250-1.
2007: Tai Yen F; Pavese Nicola; Gerhard Alexander; Tabrizi Sarah J; Barker Roger A; Brooks David J; Piccini Paola
Imaging microglial activation in Huntington's disease.
Brain research bulletin 2007;72(2-3):148-51.
2007: Kuan Wei-Li; Lin Rachel; Tyers Pam; Barker Roger A
The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias.
Neurobiology of disease 2007;25(3):594-608.
2007: Thomas Meghan G; Barker Roger A; Beazley Lyn D; Ziman Melanie R
Pax7 expression in the adult rat superior colliculus following optic nerve injury.
Neuroreport 2007;18(2):105-9.
2007: Cools Roshan; Lewis Simon J G; Clark Luke; Barker Roger A; Robbins Trevor W
L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(1):180-9.
2007: Michell A W; Tofaris G K; Gossage H; Tyers P; Spillantini M G; Barker R A
The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease.
Cell transplantation 2007;16(5):461-74.
2006: Phillips Wendy; Jennifer Morton A; Barker Roger A
Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease.
Neuroreport 2006;17(15):1623-7.
2006: Slabosz Aleksandra; Lewis Simon J G; Smigasiewicz Kamila; Szymura Blazej; Barker Roger A; Owen Adrian M
The role of learned irrelevance in attentional set-shifting impairments in Parkinson's disease.
Neuropsychology 2006;20(5):578-88.
2006: Michell A W; Xu Z; Fritz D; Lewis S J G; Foltynie T; Williams-Gray C H; Robbins T W; Carpenter R H S; Barker R A
Saccadic latency distributions in Parkinson's disease and the effects of L-dopa.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2006;174(1):7-18.
2006: Robbins A O; Ho A K; Barker R A
Weight changes in Huntington's disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(8):e7.
2006: Heath C A; Barker R A; Esmonde T F G; Harvey P; Roberts R; Trend P; Head M W; Smith C; Bell J E; Ironside J W; Will R G; Knight R S G
Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.
Journal of neurology, neurosurgery, and psychiatry 2006;77(7):880-2.
2006: Phillips Wendy; Michell Andrew W; Barker Roger A
Neurogenesis in diseases of the central nervous system.
Stem cells and development 2006;15(3):359-79.
2006: Pavese N; Gerhard A; Tai Y F; Ho A K; Turkheimer F; Barker R A; Brooks D J; Piccini P
Microglial activation correlates with severity in Huntington disease: a clinical and PET study.
Neurology 2006;66(11):1638-43.
2006: Goris A; Williams-Gray C H; Foltynie T; Compston D A S; Barker R A; Sawcer S J
No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.
American journal of human genetics 2006;78(6):1088-90; author reply 1092-4.
2006: Kuan Wei-Li; Hurelbrink Carrie B; Barker Roger A
Increased capacity for axonal outgrowth using xenogenic tissue in vitro and in a rodent model of Parkinson's disease.
Xenotransplantation 2006;13(3):233-47.
2006: Williams-Gray C H; Goris A; Foltynie T; Brown J; Maranian M; Walton A; Compston D A S; Sawcer S J; Barker R A
Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort.
Journal of neurology, neurosurgery, and psychiatry 2006;77(5):665-7.
2006: Williams-Gray Caroline H; Goris An; Foltynie Thomas; Brown Joanne; Maranian Melanie; Walton Amie; Compston D Alastair; Sawcer Stephen J; Barker Roger A
No alterations in alpha-synuclein gene dosage observed in sporadic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2006;21(5):731-2.
2006: Lazic Stanley E; Grote Helen E; Blakemore Colin; Hannan Anthony J; van Dellen Anton; Phillips Wendy; Barker Roger A
Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment.
The European journal of neuroscience 2006;23(7):1829-38.
2006: Barker Roger A
Continuing trials of GDNF in Parkinson's disease.
Lancet neurology 2006;5(4):285-6.
2006: Underwood Benjamin R; Broadhurst David; Dunn Warwick B; Ellis David I; Michell Andrew W; Vacher Coralie; Mosedale David E; Kell Douglas B; Barker Roger A; Grainger David J; Rubinsztein David C
Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles.
Brain : a journal of neurology 2006;129(Pt 4):877-86.
2006: Healy Daniel G; Abou-Sleiman Patrick M; Casas Juan P; Ahmadi Kourosh R; Lynch Timothy; Gandhi Sonia; Muqit Miratul M K; Foltynie Thomas; Barker Roger; Bhatia Kailash P; Quinn Niall P; Lees Andrew J; Gibson J Mark; Holton Janice L; Revesz Tamas; Goldstein David B; Wood Nicholas W
UCHL-1 is not a Parkinson's disease susceptibility gene.
Annals of neurology 2006;59(4):627-33.
2006: Ho Aileen K; Robbins Anna O G; Barker Roger A
Huntington's disease patients have selective problems with insight.
Movement disorders : official journal of the Movement Disorder Society 2006;21(3):385-9.
2006: Ali F R; Michell A W; Barker R A; Carpenter R H S
The use of quantitative oculometry in the assessment of Huntington's disease.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2006;169(2):237-45.
2006: Harrower T P; Tyers P; Hooks Y; Barker R A
Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
Experimental neurology 2006;197(1):56-69.
2006: Jain M; Armstrong R J E; Elneil S; Barker R A
Transplanted human neural precursor cells migrate widely but show no lesion-specific tropism in the 6-hydroxydopamine rat model of Parkinson's disease.
Cell transplantation 2006;15(7):579-93.
2006: Farrington M; Wreghitt T G; Lever A M L; Dunnett S B; Rosser A E; Barker R A
Neural transplantation in Huntington's disease: the NEST-UK donor tissue microbiological screening program and review of the literature.
Cell transplantation 2006;15(4):279-94.
2006: Williams-Gray Caroline H; Foltynie Thomas; Lewis Simon J G; Barker Roger A
Cognitive deficits and psychosis in Parkinson's disease: a review of pathophysiology and therapeutic options.
CNS drugs 2006;20(6):477-505.
2006: Swainson R; SenGupta D; Shetty T; Watkins L H A; Summers B A; Sahakian B J; Polkey C E; Barker R A; Robbins T W
Impaired dimensional selection but intact use of reward feedback during visual discrimination learning in Parkinson's disease.
Neuropsychologia 2006;44(8):1290-304.
2005: Phillips Wendy; Morton A Jennifer; Barker Roger A
Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(50):11564-76.
2005: Cheesman A L; Barker R A; Lewis S J G; Robbins T W; Owen A M; Brooks D J
Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2005;76(9):1204-10.
2005: Kuan W-L; Barker R A
New therapeutic approaches to Parkinson's disease including neural transplants.
Neurorehabilitation and neural repair 2005;19(3):155-81.
2005: Harrower Timothy P; Michell Andrew W; Barker Roger A
Lewy bodies in Parkinson's disease: protectors or perpetrators?
Experimental neurology 2005;195(1):1-6.
2005: Barker Roger A
The neurological assessment of patients in vegetative and minimally conscious states.
Neuropsychological rehabilitation 2005;15(3-4):214-23.
2005: Foltynie Thomas; Lewis Simon G J; Goldberg Terry E; Blackwell Andrew D; Kolachana Bhaskar S; Weinberger Daniel R; Robbins Trevor W; Barker Roger A
The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease.
Journal of neurology 2005;252(7):833-8.
2005: Michell Andrew W; Luheshi Leila M; Barker Roger A
Skin and platelet alpha-synuclein as peripheral biomarkers of Parkinson's disease.
Neuroscience letters 2005;381(3):294-8.
2005: Hurelbrink Carrie B; Lewis Simon J G; Barker Roger A
The use of the Actiwatch-Neurologica system to objectively assess the involuntary movements and sleep-wake activity in patients with mild-moderate Huntington's disease.
Journal of neurology 2005;252(6):642-7.
2005: Foltynie Thomas; Hicks Andrew; Sawcer Stephen; Jonasdottir Aslaug; Setakis Efrosini; Maranian Melanie; Yeo Taiwai; Lewis Simon; Brayne Carol; Stefansson Kari; Compston Alastair; Gulcher Jeff; Barker Roger A
A genome wide linkage disequilibrium screen in Parkinson's disease.
Journal of neurology 2005;252(5):597-602.
2005: Pyle Angela; Foltynie Thomas; Tiangyou Watcharee; Lambert Claire; Keers Sharon M; Allcock Liesl M; Davison Jill; Lewis Simon J; Perry Robert H; Barker Roger; Burn David J; Chinnery Patrick F
Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD.
Annals of neurology 2005;57(4):564-7.
2005: Michell A W; Barker R A; Raha S K; Raha-Chowdhury R
A case of late onset sporadic Parkinson's disease with an A53T mutation in alpha-synuclein.
Journal of neurology, neurosurgery, and psychiatry 2005;76(4):596-7.
2005: Hurelbrink Carrie B; Barker Roger A
Migration of cells from primary transplants of allo- and xenografted foetal striatal tissue in the adult rat brain.
The European journal of neuroscience 2005;21(6):1503-10.
2005: Harrower Timothy; Barker Roger A
Cell therapies for neurological disease--from bench to clinic to bench.
Expert opinion on biological therapy 2005;5(3):289-91.
2005: Lewis S J G; Foltynie T; Blackwell A D; Robbins T W; Owen A M; Barker R A
Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.
Journal of neurology, neurosurgery, and psychiatry 2005;76(3):343-8.
2005: Longworth C E; Keenan S E; Barker R A; Marslen-Wilson W D; Tyler L K
The basal ganglia and rule-governed language use: evidence from vascular and degenerative conditions.
Brain : a journal of neurology 2005;128(Pt 3):584-96.
2005: Morton A Jennifer; Wood Nigel I; Hastings Michael H; Hurelbrink Carrie; Barker Roger A; Maywood Elizabeth S
Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(1):157-63.
2005: Lewis Simon J G; Slabosz Aleksandra; Robbins Trevor W; Barker Roger A; Owen Adrian M
Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease.
Neuropsychologia 2005;43(6):823-32.
2004: Ho Aileen K; Sahakian Barbara J; Robbins Trevor W; Barker Roger A
Random number generation in patients with symptomatic and presymptomatic Huntington's disease.
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 2004;17(4):208-12.
2004: Ho Aileen K; Robbins Anna O G; Walters Stephen J; Kaptoge Stephen; Sahakian Barbara J; Barker Roger A
Health-related quality of life in Huntington's disease: a comparison of two generic instruments, SF-36 and SIP.
Movement disorders : official journal of the Movement Disorder Society 2004;19(11):1341-8.
2004: Barker Roger A; Widner Håkan
Immune problems in central nervous system cell therapy.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(4):472-81.
2004: Michell A W; Phillips W; Barker R A
Can endogenous stem cells be stimulated to repair the degenerating brain?
The Journal of pharmacy and pharmacology 2004;56(10):1201-10.
2004: Foltynie Thomas; Goldberg Terry E; Lewis Simon G J; Blackwell Andrew D; Kolachana Bhaskar S; Weinberger Daniel R; Robbins Trevor W; Barker Roger A
Planning ability in Parkinson's disease is influenced by the COMT val158met polymorphism.
Movement disorders : official journal of the Movement Disorder Society 2004;19(8):885-91.
2004: Michell A W; Lewis S J G; Foltynie T; Barker R A
Biomarkers and Parkinson's disease.
Brain : a journal of neurology 2004;127(Pt 8):1693-705.
2004: Wilkins Alastair; Brown Jerry M; Barker Roger A
SCA2 presenting as levodopa-responsive parkinsonism in a young patient from the United Kingdom: a case report.
Movement disorders : official journal of the Movement Disorder Society 2004;19(5):593-5.
2004: Sayles Mark; Jain Meena; Barker Roger A
The cellular repair of the brain in Parkinson's disease--past, present and future.
Transplant immunology 2004;12(3-4):321-42.
2004: Ho Aileen K; Nestor Peter J; Williams Guy B; Bradshaw John L; Sahakian Barbara J; Robbins Trevor W; Barker Roger A
Pseudo-neglect in Huntington's disease correlates with decreased angular gyrus density.
Neuroreport 2004;15(6):1061-4.
2004: Lazic Stanley E; Grote Helen; Armstrong Richard J E; Blakemore Colin; Hannan Anthony J; van Dellen Anton; Barker Roger A
Decreased hippocampal cell proliferation in R6/1 Huntington's mice.
Neuroreport 2004;15(5):811-3.
2004: Lazic Stanley E; Barker Roger A
Rapid decline in motor symptoms in HD neural transplant patients prior to surgery.
Brain research bulletin 2004;63(1):83-4.
2004: Barker Roger A; Foltynie Thomas
The future challenges in Parkinson's disease.
Journal of neurology 2004;251(3):361-5.
2004: Foltynie Thomas; Brayne Carol E G; Robbins Trevor W; Barker Roger A
The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study.
Brain : a journal of neurology 2004;127(Pt 3):550-60.
2004: Harrower Timothy P; Barker Roger A
The emerging technologies of neural xenografting and stem cell transplantation for treating neurodegenerative disorders.
Drugs of today (Barcelona, Spain : 1998) 2004;40(2):171-89.
2004: Lewis Simon J G; Dove Anja; Robbins Trevor W; Barker Roger A; Owen Adrian M
Striatal contributions to working memory: a functional magnetic resonance imaging study in humans.
The European journal of neuroscience 2004;19(3):755-60.
2004: Harrower T P; Richards A; Cruz G; Copeman L; Dunnett S B; Barker R A
Complement regulatory proteins are expressed at low levels in embryonic human, wild type and transgenic porcine neural tissue.
Xenotransplantation 2004;11(1):60-71.
2004: Hurelbrink Carrie B; Barker Roger A
The potential of GDNF as a treatment for Parkinson's disease.
Experimental neurology 2004;185(1):1-6.
2004: Harrower Timothy P; Barker Roger A
Is there a future for neural transplantation?
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2004;18(3):141-53.
2003: Lazic Stanley E; Barker Roger A
The future of cell-based transplantation therapies for neurodegenerative disorders.
Journal of hematotherapy & stem cell research 2003;12(6):635-42.
2003: Ho A K; Sahakian B J; Brown R G; Barker R A; Hodges J R; Ané M-N; Snowden J; Thompson J; Esmonde T; Gentry R; Moore J W; Bodner T;
Profile of cognitive progression in early Huntington's disease.
Neurology 2003;61(12):1702-6.
2003: Aron Adam R; Watkins Laura; Sahakian Barbara J; Monsell Stephen; Barker Roger A; Robbins Trevor W
Task-set switching deficits in early-stage Huntington's disease: implications for basal ganglia function.
Journal of cognitive neuroscience 2003;15(5):629-42.
2003: Lewis Simon J G; Dove Anja; Robbins Trevor W; Barker Roger A; Owen Adrian M
Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(15):6351-6.
2003: Björklund Anders; Dunnett Stephen B; Brundin Patrik; Stoessl A Jon; Freed Curt R; Breeze Robert E; Levivier Marc; Peschanski Marc; Studer Lorenz; Barker Roger
Neural transplantation for the treatment of Parkinson's disease.
Lancet neurology 2003;2(7):437-45.
2003: Jain Meena; Armstrong Richard J E; Elneil Suzie; Rosser Anne E; Barker Roger A
Migration and differentiation of transplanted human neural precursor cells.
Neuroreport 2003;14(9):1257-62.
2003: Jain Meena; Armstrong Richard J E; Tyers Pamela; Barker Roger A; Rosser Anne E
GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro.
Experimental neurology 2003;182(1):113-23.
2003: Armstrong Richard J E; Tyers Pamela; Jain Meena; Richards Andrew; Dunnett Stephen B; Rosser Anne E; Barker Roger A
Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson's disease.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2003;151(2):204-17.
2003: Ho Aileen K; Manly Tom; Nestor Peter J; Sahakian Barbara J; Bak Thomas H; Robbins Trevor W; Rosser Anne E; Barker Roger A
A case of unilateral neglect in Huntington's disease.
Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology 2003;9(3):261-73.
2003: Barker R A; Foltynie T
How common is dementia with Lewy bodies?
Journal of neurology, neurosurgery, and psychiatry 2003;74(6):697-8.
2003: Barker R A; Jain M; Armstrong R J E; Caldwell M A
Stem cells and neurological disease.
Journal of neurology, neurosurgery, and psychiatry 2003;74(5):553-7.
2003: Pavese Nicola; Andrews Thomasin C; Brooks David J; Ho Aileen K; Rosser Anne E; Barker Roger A; Robbins Trevor W; Sahakian Barbara J; Dunnett Stephen B; Piccini Paola
Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.
Brain : a journal of neurology 2003;126(Pt 5):1127-35.
2003: Lewis Simon J G; Caldwell Maeve A; Barker Roger A
Modern therapeutic approaches in Parkinson's disease.
Expert reviews in molecular medicine 2003;5(10):1-20.
2003: Aron A R; Schlaghecken F; Fletcher P C; Bullmore E T; Eimer M; Barker R; Sahakian B J; Robbins T W
Inhibition of subliminally primed responses is mediated by the caudate and thalamus: evidence from functional MRI and Huntington's disease.
Brain : a journal of neurology 2003;126(Pt 3):713-23.
2003: Hurelbrink Carrie B; Tyers Pam; Armstrong Richard J E; Dunnett Stephen B; Barker Roger A; Rosser Anne E
Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease.
Cell transplantation 2003;12(7):687-95.
2003: Rosser A E; Barker R A; Armstrong R J E; Elneil S; Jain M; Hurelbrink C B; Prentice A; Carne C; Thornton S; Hutchinson H; Dunnett S B
Staging and preparation of human fetal striatal tissue for neural transplantation in Huntington's disease.
Cell transplantation 2003;12(7):679-86.
2003: Cools Roshan; Barker Roger A; Sahakian Barbara J; Robbins Trevor W
L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease.
Neuropsychologia 2003;41(11):1431-41.
2003: Lewis Simon J G; Cools Roshan; Robbins Trevor W; Dove Anja; Barker Roger A; Owen Adrian M
Using executive heterogeneity to explore the nature of working memory deficits in Parkinson's disease.
Neuropsychologia 2003;41(6):645-54.
2002: Rosser A E; Barker R A; Harrower T; Watts C; Farrington M; Ho A K; Burnstein R M; Menon D K; Gillard J H; Pickard J; Dunnett S B;
Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475.
Journal of neurology, neurosurgery, and psychiatry 2002;73(6):678-85.
2002: Foltynie T; Sawcer S; Brayne C; Barker R A
The genetic basis of Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(4):363-70.
2002: Armstrong Richard J E; Hurelbrink Carrie B; Tyers Pam; Ratcliffe Emma L; Richards Andrew; Dunnett Stephen B; Rosser Anne E; Barker Roger A
The potential for circuit reconstruction by expanded neural precursor cells explored through porcine xenografts in a rat model of Parkinson's disease.
Experimental neurology 2002;175(1):98-111.
2002: Hurelbrink Carrie B; Armstrong Richard J E; Dunnett Stephen B; Rosser Anne E; Barker Roger A
Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.
The European journal of neuroscience 2002;15(7):1255-66.
2002: Harrower T P; Richards A; Cruz G; Copeman L; Dunnett S B; Barker R A
Alpha Gal is widely expressed in embryonic porcine stem cells and neural tissue.
Neuroreport 2002;13(4):481-5.
2002: Barker Roger A
Repairing the brain in Parkinson's disease: where next?
Movement disorders : official journal of the Movement Disorder Society 2002;17(2):233-41.
2002: Cools Roshan; Stefanova Elka; Barker Roger A; Robbins Trevor W; Owen Adrian M
Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.
Brain : a journal of neurology 2002;125(Pt 3):584-94.
2002: Foltynie Thomas; Brayne Carol; Barker Roger A
The heterogeneity of idiopathic Parkinson's disease.
Journal of neurology 2002;249(2):138-45.
2002: Foltynie Thomas; Barker Roger; Brayne Carol
Vascular parkinsonism: a review of the precision and frequency of the diagnosis.
Neuroepidemiology 2002;21(1):1-7.
2002: Ho Aileen K; Sahakian Barbara J; Robbins Trevor W; Barker Roger A; Rosser Anne E; Hodges John R
Verbal fluency in Huntington's disease: a longitudinal analysis of phonemic and semantic clustering and switching.
Neuropsychologia 2002;40(8):1277-84.
2001: Cools R; Barker R A; Sahakian B J; Robbins T W
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands.
Cerebral cortex (New York, N.Y. : 1991) 2001;11(12):1136-43.
2001: Cools R; Barker R A; Sahakian B J; Robbins T W
Mechanisms of cognitive set flexibility in Parkinson's disease.
Brain : a journal of neurology 2001;124(Pt 12):2503-12.
2001: Barker R A
Getting to the heart of dementia.
Journal of neurology, neurosurgery, and psychiatry 2001;71(5):574-5.
2001: Hurelbrink C B; Barker R A
Prospects for the treatment of Parkinson's disease using neurotrophic factors.
Expert opinion on pharmacotherapy 2001;2(10):1531-43.
2001: Armstrong R J; Barker R A
Neurodegeneration: a failure of neuroregeneration?
Lancet 2001;358(9288):1174-6.
2001: Hurelbrink C B; Armstrong R J; Luheshi L M; Dunnett S B; Rosser A E; Barker R A
Death of dopaminergic neurons in vitro and in nigral grafts: reevaluating the role of caspase activation.
Experimental neurology 2001;171(1):46-58.
2001: Jain M; Armstrong R J; Barker R A; Rosser A E
Cellular and molecular aspects of striatal development.
Brain research bulletin 2001;55(4):533-40.
2001: Armstrong R J; Harrower T P; Hurelbrink C B; McLaughin M; Ratcliffe E L; Tyers P; Richards A; Dunnett S B; Rosser A E; Barker R A
Porcine neural xenografts in the immunocompetent rat: immune response following grafting of expanded neural precursor cells.
Neuroscience 2001;106(1):201-16.
2000: Hurelbrink C B; Armstrong R J; Barker R A; Dunnett S B; Rosser A E
Hibernated human fetal striatal tissue: successful transplantation in a rat model of Huntington's disease.
Cell transplantation 2000;9(6):743-9.
2000: Barker R A
Prospects for the treatment of Parkinson's disease using neural grafts.
Expert opinion on pharmacotherapy 2000;1(5):889-902.
2000: Barker R A; Ratcliffe E; McLaughlin M; Richards A; Dunnett S B
A role for complement in the rejection of porcine ventral mesencephalic xenografts in a rat model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(9):3415-24.
2000: Barker R A; Kendall A L; Widner H
Neural tissue xenotransplantation: what is needed prior to clinical trials in Parkinson's disease? Neural Tissue Xenografting Project.
Cell transplantation 2000;9(2):235-46.
2000: Barker R A
Porcine neural xenografts: what are the issues?
Novartis Foundation symposium 2000;231():184-96; discussion 196-201, 302-6.
1999: Barker R A; Dunnett S B
Functional integration of neural grafts in Parkinson's disease.
Nature neuroscience 1999;2(12):1047-8.
1999: Barker R A; Ratcliffe E; Richards A; Dunnett S B
Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age.
Cell transplantation 1999;8(6):593-9.
1999: Barker R A; Dick D J; Cochius J I
Delayed postanoxic encephalopathy and pseudodeficiency of arylsulphatase A.
Journal of neurology 1999;246(11):1103-4.
1999: Barker R A; Dunnett S B; Richards A
The rejection of neural xenotransplants: a role for antibodies.
Transplantation 1999;68(8):1091-2.
1999: Barker R A; Anderson J R; Meyer P; Dick D J; Scolding N J
Microangiopathy of the brain and retina with hearing loss in a 50 year old woman: extending the spectrum of Susac's syndrome.
Journal of neurology, neurosurgery, and psychiatry 1999;66(5):641-3.
1998: Dunnett S B; Torres E M; Richards H; Barker R A
Effects of surgical anaesthesia on the viability of nigral grafts in the rat striatum.
Cell transplantation 1998;7(6):567-72.
1998: Barker R A; Revesz T; Thom M; Marsden C D; Brown P
Review of 23 patients affected by the stiff man syndrome: clinical subdivision into stiff trunk (man) syndrome, stiff limb syndrome, and progressive encephalomyelitis with rigidity.
Journal of neurology, neurosurgery, and psychiatry 1998;65(5):633-40.
1998: Molyneux P D; Barker R A; Thom M; van Paesschen W; Harkness W F; Duncan J S
Successful treatment of intractable epilepsia partialis continua with multiple subpial transections.
Journal of neurology, neurosurgery, and psychiatry 1998;65(1):137-8.
1998: Barker R A; Phillips R R; Moseley I F; Taylor W J; Kitchen N D; Scadding J W
Posterior communicating artery aneurysm presenting with haemorrhage into an arachnoid cyst.
Journal of neurology, neurosurgery, and psychiatry 1998;64(4):558-60.
1998: Barker R A; Knowles G K; Sheppard M N
Breathlessness and profuse haemoptysis.
Lancet 1998;351(9096):108.
1997: Annett L E; Torres E M; Clarke D J; Ishida Y; Barker R A; Ridley R M; Baker H F; Dunnett S B
Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age.
Cell transplantation 1997;6(6):557-69.
1997: Barker R A; Marsden C D
Successful treatment of stiff man syndrome with intravenous immunoglobulin.
Journal of neurology, neurosurgery, and psychiatry 1997;62(4):426-7.
1997: Silver N C; Barker R A; MacManus D G; Barker G J; Thom M; Thomas D G; McDonald W I; Miller D H
Proton magnetic resonance spectroscopy in a pathologically confirmed acute demyelinating lesion.
Journal of neurology 1997;244(3):204-7.
1996: Fricker R A; Barker R A; Fawcett J W; Dunnett S B
A comparative study of preparation techniques for improving the viability of striatal grafts using vital stains, in vitro cultures, and in vivo grafts.
Cell transplantation 1996;5(6):599-611.
1996: Barker R A; Dunnett S B; Faissner A; Fawcett J W
The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum.
Experimental neurology 1996;141(1):79-93.
1996: Barker R
Tachykinins, neurotrophism and neurodegenerative diseases: a critical review on the possible role of tachykinins in the aetiology of CNS diseases.
Reviews in the neurosciences 1996;7(3):187-214.
1995: Barker R A; Fricker R A; Abrous D N; Fawcett J; Dunnett S B
A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts.
Cell transplantation 1995;4(2):173-200.
1995: Fawcett J W; Barker R A; Dunnett S B
Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1995;106(2):275-82.
1994: Barker R; Dunnett S B
Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1994;101(3):365-74.
1993: Barker R; Dunnett S; Fawcett J
Immunohistochemical identification of rat adrenal cortical tissue in situ, in vitro, and in intracerebral adrenal grafts.
Experimental neurology 1993;122(1):125-9.
1993: Barker R; Dunnett S
The biology and behaviour of intracerebral adrenal transplants in animals and man.
Reviews in the neurosciences 1993;4(2):113-46.
1993: Barker R; Dunnett S; Fawcett J
A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;92(3):467-72.
1992: Barker R
Neuropathological features of Alzheimer's disease in non-demented parkinsonian patients.
Journal of neurology, neurosurgery, and psychiatry 1992;55(6):525.
1991: Barker R
Substance P and neurodegenerative disorders. A speculative review.
Neuropeptides 1991;20(2):73-8.
1988: Barker R A; Cahn A P
Parkinson's disease: an autoimmune process.
The International journal of neuroscience 1988;43(1-2):1-7.
1988: Barker R A
The basal ganglia and pain.
The International journal of neuroscience 1988;41(1-2):29-34.
1986: Barker R
Substance P and Parkinson's disease: a causal relationship?
Journal of theoretical biology 1986;120(3):353-62.

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