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Tit Meng Lim

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Jacqueline L Y Chee; Hani Gabra; David P Lane; Sai Mun Leong; Paul M Neilsen; Jacqueline E Noll; Yi Ting Phua; Suzan Saidin; Tit Meng Lim
Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9.
Haiyan Guo; Yukti Choudhury; Jing Yang; Can Chen; Felix Chang Tay; Tit Meng Lim; Shu Wang
Antiglioma effects of combined use of a baculovirual vector expressing wild-type p53 and sodium butyrate.
Zhi Dong Zhou; Yu Hong Lan; Eng-King Tan; Tit Meng Lim
Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: implications for iron-related dopaminergic neuron degeneration.

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2013: Jacqueline L Y Chee; Hani Gabra; David P Lane; Sai Mun Leong; Paul M Neilsen; Jacqueline E Noll; Yi Ting Phua; Suzan Saidin; Tit Meng Lim
Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9.
Cell cycle (Georgetown, Tex.) 2013;12(2):278-88.
2011: Haiyan Guo; Yukti Choudhury; Jing Yang; Can Chen; Felix Chang Tay; Tit Meng Lim; Shu Wang
Antiglioma effects of combined use of a baculovirual vector expressing wild-type p53 and sodium butyrate.
The journal of gene medicine 2011;13(1):26-36.
2010: Zhi Dong Zhou; Yu Hong Lan; Eng-King Tan; Tit Meng Lim
Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: implications for iron-related dopaminergic neuron degeneration.
Free radical biology & medicine 2010;49(12):1856-71.
2010: Zhi Dong Zhou; Tit Meng Lim
Glutathione conjugates with dopamine-derived quinones to form reactive or non-reactive glutathione-conjugates.
Neurochemical research 2010;35(11):1805-18.
2010: Sai Mun Leong; Ban Xiong Tan; Baidah Bte Ahmad; Tie Yan; Lai Yuen Chee; Swee Tin Ang; Kian Ghee Tay; Liang-Piu Koh; Allen Eng Juh Yeoh; Evelyn Siew-Chuan Koay; Yu-Keung Mok; Tit Meng Lim
Mutant nucleophosmin deregulates cell death and myeloid differentiation through excessive caspase-6 and -8 inhibition.
Blood 2010;116(17):3286-96.
2010: Wee-Kee Tan; Tit Meng Lim; Chiang-Shiong Loh
A simple, rapid method to isolate salt glands for three-dimensional visualization, fluorescence imaging and cytological studies.
Plant methods 2010;6():24.
2010: Ming Liu; Tit Meng Lim; Yu Cai
The Drosophila female germline stem cell lineage acts to spatially restrict DPP function within the niche.
Science signaling 2010;3(132):ra57.
2009: Zhi Dong Zhou; Tit Meng Lim
Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones.
Free radical research 2009;43(4):417-30.
2009: Zhi Dong Zhou; Sze Yen Kerk; Gao Gao Xiong; Tit Meng Lim
Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.
Journal of neurochemistry 2009;108(3):601-10.
2009: Zhi Dong Zhou; Tit Meng Lim
Roles of glutathione (GSH) in dopamine (DA) oxidation studied by improved tandem HPLC plus ESI-MS.
Neurochemical research 2009;34(2):316-26.
2008: Ai-Cheng Lee; Ziyu Dai; Baowei Chen; Hong Wu; Jun Wang; Aiguo Zhang; Lurong Zhang; Tit Meng Lim; Yuehe Lin
Electrochemical branched-DNA assay for polymerase chain reaction-free detection and quantification of oncogenes in messenger RNA.
Analytical chemistry 2008;80(24):9402-10.
2008: Meera Gurumurthy; Chuan Hao Tan; Raymond Ng; Lisa Zeiger; Joanne Lau; Jialing Lee; Anwesha Dey; Robin Philp; Qintong Li; Tit Meng Lim; David H Price; David P Lane; Sheng-Hao Chao
Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription.
Journal of molecular biology 2008;378(2):302-17.
2008: Hong Miao Ji; Victor Samper; Yu Chen; Chew-Kiat Heng; Tit Meng Lim; Levent Yobas
Silicon-based microfilters for whole blood cell separation.
Biomedical microdevices 2008;10(2):251-7.
2008: Yefang Zhou; Dietmar W Hutmacher; Varawan Sae-Lim; Zhihong Zhou; Maria Woodruff; Tit Meng Lim
Osteogenic and adipogenic induction potential of human periodontal cells.
Journal of periodontology 2008;79(3):525-34.
2008: Sok-Siam Gouk; Tit Meng Lim; Swee-Hin Teoh; Wendell Q Sun
Alterations of human acellular tissue matrix by gamma irradiation: histology, biomechanical property, stability, in vitro cell repopulation, and remodeling.
Journal of biomedical materials research. Part B, Applied biomaterials 2008;84(1):205-17.
2007: Christina H L Teh; Chin Chieh Loh; Kevin K Y Lam; Jia Min Loo; Tie Yan; Tit Meng Lim
Neuronal PAS domain protein 1 regulates tyrosine hydroxylase level in dopaminergic neurons.
Journal of neuroscience research 2007;85(8):1762-73.
2007: Yefang Zhou; Fulin Chen; Saey Tuan Ho; Maria Ann Woodruff; Tit Meng Lim; Dietmar W Hutmacher
Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts.
Biomaterials 2007;28(5):814-24.
2006: Christina H L Teh; Kevin K Y Lam; Chin C Loh; Jia M Loo; Tie Yan; Tit Meng Lim
Neuronal PAS domain protein 1 is a transcriptional repressor and requires arylhydrocarbon nuclear translocator for its nuclear localization.
The Journal of biological chemistry 2006;281(45):34617-29.
2006: Ai Mei Chou; Varawan Sae-Lim; Dietmar W Hutmacher; Tit Meng Lim
Tissue engineering of a periodontal ligament-alveolar bone graft construct.
The International journal of oral & maxillofacial implants 2006;21(4):526-34.
2006: Y F Zhou; Varawan Sae-Lim; Ai Mei Chou; Dietmar W Hutmacher; Tit Meng Lim
Does seeding density affect in vitro mineral nodules formation in novel composite scaffolds?
Journal of biomedical materials research. Part A 2006;78(1):183-93.
2006: Gu-ping Tang; H Y Guo; F Alexis; Xin Wang; S Zeng; Tit Meng Lim; J Ding; Yi-Yan Yang; Shu Wang
Low molecular weight polyethylenimines linked by beta-cyclodextrin for gene transfer into the nervous system.
The journal of gene medicine 2006;8(6):736-44.
2006: Z D Zhou; B P Yap; A Y T Gung; S M Leong; S T Ang; Tit Meng Lim
Dopamine-related and caspase-independent apoptosis in dopaminergic neurons induced by overexpression of human wild type or mutant alpha-synuclein.
Experimental cell research 2006;312(2):156-70.
2005: Cheng Wang; Han Seok Ko; Bobby Thomas; Fai Tsang; Katherine C M Chew; Shiam-Peng Tay; Michelle W L Ho; Tit Meng Lim; Tuck Wah Soong; Olga Pletnikova; Juan C Troncoso; Valina Dawson; Ted M Dawson; Kah Leong Lim
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.
Human molecular genetics 2005;14(24):3885-97.
2005: Anthony K F Liou; Zhigang Zhou; Wei Pei; Tit Meng Lim; Xiao-Ming Yin; Jun Chen
BimEL up-regulation potentiates AIF translocation and cell death in response to MPTP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1350-2.
2005: Chao-Yang Wang; H Y Guo; Tit Meng Lim; Yee-Kong NG; H P Neo; Peter Y K Hwang; Woon-Chee Yee; Shu Wang
Improved neuronal transgene expression from an AAV-2 vector with a hybrid CMV enhancer/PDGF-beta promoter.
The journal of gene medicine 2005;7(7):945-55.
2005: Jian-Shan Ye; Huifang Cui; Xiao Liu; Tit Meng Lim; Wei-De Zhang; Fwu-Shan Sheu
Preparation and characterization of aligned carbon nanotube-ruthenium oxide nanocomposites for supercapacitors.
Small (Weinheim an der Bergstrasse, Germany) 2005;1(5):560-5.
2005: Sok-Siam Gouk; Nikolai M Kocherginsky; Yuri Yu Kostetski; Herbert O Moser; Ping Yang; Tit Meng Lim; Wendell Q Sun
Synchrotron radiation-induced formation and reactions of free radicals in human acellular dermal matrix.
Radiation research 2005;163(5):535-43.
2005: Zengshuan Ma; Tit Meng Lim; Lee-Yong Lim
Pharmacological activity of peroral chitosan-insulin nanoparticles in diabetic rats.
International journal of pharmaceutics 2005;293(1-2):271-80.
2005: Cheng Wang; Jeanne Tan; Michelle W L Ho; Norazean Zaiden; Siew Heng Wong; Constance L C Chew; Pei Woon Eng; Tit Meng Lim; Ted M Dawson; Kah Leong Lim
Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations.
Journal of neurochemistry 2005;93(2):422-31.
2005: J L Y Chee; Xueli Guan; J Y Lee; B Dong; S M Leong; E H Ong; Anthony K F Liou; Tit Meng Lim
Compensatory caspase activation in MPP+-induced cell death in dopaminergic neurons.
Cellular and molecular life sciences : CMLS 2005;62(2):227-38.
2004: Hui Ming Yang; Psyche Huu-Hoa Lee; Tit Meng Lim; Fwu-Shan Sheu
Neurogranin expression in stably transfected N2A cell line affects cytosolic calcium level by nitric oxide stimulation.
Brain research. Molecular brain research 2004;129(1-2):171-8.
2003: Jalel BEN GHOZZIA; Tit Meng Lim; Violet P E Phang; Woon Khiong Chan
Cloning and tissue expression of 6-pyruvoyl tetrahydropterin synthase and xanthine dehydrogenase from Poecilia reticulata.
Marine biotechnology (New York, N.Y.) 2003;5(6):568-78.
2003: Kah Leong Lim; Tit Meng Lim
Molecular mechanisms of neurodegeneration in Parkinson's disease: clues from Mendelian syndromes.
IUBMB life 2003;55(6):315-22.
2003: Gideon Khoo; Meng Huat Lim; Haridas Suresh; Damien K Y Gan; Kok Fang Lim; Fan Chen; Woon Khiong Chan; Tit Meng Lim; Violet P E Phang
Genetic linkage maps of the guppy ( Poecilia reticulata): assignment of RAPD markers to multipoint linkage groups.
Marine biotechnology (New York, N.Y.) 2003;5(3):279-93.
2003: Putanae S Srinivasa Rao; Tit Meng Lim; Ka Yin Leung
Functional genomics approach to the identification of virulence genes involved in Edwardsiella tarda pathogenesis.
Infection and immunity 2003;71(3):1343-51.
2003: Tit Meng Lim
Learning developmental biology has priority in the life sciences curriculum in Singapore.
The International journal of developmental biology 2003;47(2-3):117-21.
2002: Cheong-Huat Tan; Thean-Chu Lee; Shyamal D Weeraratne; Vladimir Korzh; Tit Meng Lim; Zhiyuan Gong
Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults.
Mechanisms of development 2002;119 Suppl 1():S221-4.
2002: Cheong-Huat Tan; Thean-Chu Lee; Shyamal D Weeraratne; Vladimir Korzh; Tit Meng Lim; Zhiyuan Gong
Ziwi, the zebrafish homologue of the Drosophila piwi: co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults.
Gene expression patterns : GEP 2002;2(3-4):257-60.
2002: Gideon Khoo; Kok Fang Lim; Damien K Y Gan; Fan Chen; Woon Khiong Chan; Tit Meng Lim; Violet P E Phang
Genetic diversity within and among feral populations and domesticated strains of the guppy (Poecilia reticulata) in Singapore.
Marine biotechnology (New York, N.Y.) 2002;4(4):367-78.
2001: Putanae S Srinivasa Rao; Tit Meng Lim; Ka Yin Leung
Opsonized virulent Edwardsiella tarda strains are able to adhere to and survive and replicate within fish phagocytes but fail to stimulate reactive oxygen intermediates.
Infection and immunity 2001;69(9):5689-97.
2001: J A Mathew; Yuen Peng Tan; Putanae S Srinivasa Rao; Tit Meng Lim; Ka Yin Leung
Edwardsiella tarda mutants defective in siderophore production, motility, serum resistance and catalase activity.
Microbiology (Reading, England) 2001;147(Pt 2):449-57.
2001: S H Ling; XH Wang; Tit Meng Lim; Ka Yin Leung
Green fluorescent protein-tagged Edwardsiella tarda reveals portal of entry in fish.
FEMS microbiology letters 2001;194(2):239-43.
2000: Yanfei Xu; Jiangyan He; Xukun Wang; Tit Meng Lim; Zhiyuan Gong
Asynchronous activation of 10 muscle-specific protein (MSP) genes during zebrafish somitogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists 2000;219(2):201-15.
2000: Kim Lee Chua; Tit Meng Lim
Type I and type II cytokeratin cDNAs from the zebrafish (Danio rerio) and expression patterns during early development.
Differentiation; research in biological diversity 2000;66(1):31-41.
2000: S H Loh; W T Chan; Zhiyuan Gong; Tit Meng Lim; Kim Lee Chua
Characterization of a zebrafish (Danio rerio) desmin cDNA: an early molecular marker of myogenesis.
Differentiation; research in biological diversity 2000;65(5):247-54.
2000: Wei-Yi Ong; H M Lim; Tit Meng Lim; B Lutz
Kainate-induced neuronal injury leads to persistent phosphorylation of cAMP response element-binding protein in glial and endothelial cells in the hippocampus.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2000;131(2):178-86.
2000: Wei-Yi Ong; Chang-Yong Hu; Y P Soh; Tit Meng Lim; Peter G Pentchev; Shutish C Patel
Neuronal localization of sterol regulatory element binding protein-1 in the rodent and primate brain: a light and electron microscopic immunocytochemical study.
Neuroscience 2000;97(1):143-53.
2000: S H Ling; XH Wang; L Xie; Tit Meng Lim; Ka Yin Leung
Use of green fluorescent protein (GFP) to study the invasion pathways of Edwardsiella tarda in in vivo and in vitro fish models.
Microbiology (Reading, England) 2000;146 ( Pt 1)():7-19.
1999: Luoping Li; Y Li; Tit Meng Lim; Shen Q Pan
GFP-aided confocal laser scanning microscopy can monitor Agrobacterium tumefaciens cell morphology and gene expression associated with infection.
FEMS microbiology letters 1999;179(1):141-6.
1999: Wei-Yi Ong; Min-Qin Ren; J Makjanić; Tit Meng Lim; Frank Watt
A nuclear microscopic study of elemental changes in the rat hippocampus after kainate-induced neuronal injury.
Journal of neurochemistry 1999;72(4):1574-9.
1998: XH Wang; H L Oon; G W Ho; W S Fred Wong; Tit Meng Lim; Ka Yin Leung
Internalization and cytotoxicity are important virulence mechanisms in Vibrio-fish epithelial cell interactions.
Microbiology (Reading, England) 1998;144 ( Pt 11)():2987-3002.
1998: Wei-Yi Ong; Tit Meng Lim; Laurence J Garey
A light and electron microscopic study of the metabotropic glutamate receptor mGluR1a in the normal and kainate-lesioned rat hippocampus.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1998;35(1-3):173-86.
1998: W L Shee; Wei-Yi Ong; Tit Meng Lim
Distribution of perlecan in mouse hippocampus following intracerebroventricular kainate injections.
Brain research 1998;799(2):292-300.
1996: Tit Meng Lim; C G Chng; Sek-Man Wong
Study of the three-dimensional images of potyvirus-induced cytoplasmic inclusions using confocal laser scanning microscopy.
Journal of virological methods 1996;60(2):139-45.
1996: Sek-Man Wong; C G Chng; Y H Lee; Tit Meng Lim
An appraisal of the banded and paracrystalline cytoplasmic inclusions induced in cymbidium mosaic potexvirus- and odontoglossum ringspot tobamovirus infected orchid cells using confocal laser scanning microscropy.
Archives of virology 1996;141(2):231-42.
1995: C L Foo; K R Dinesh; Tit Meng Lim; Woon Khiong Chan; V P Phang
Inheritance of RAPD markers in the guppy fish, Poecilia reticulata.
Zoological science 1995;12(5):535-41.
1995: Timothy J Inglis; Tit Meng Lim; M L Ng; E K Tang; K P Hui
Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation.
Chest 1995;108(4):1049-52.
1993: K R Dinesh; Tit Meng Lim; Kim Lee Chua; Woon Khiong Chan; V P Phang
RAPD analysis: an efficient method of DNA fingerprinting in fishes.
Zoological science 1993;10(5):849-54.
1993: T P Laudel; Tit Meng Lim
Development of the dorsal root ganglion in a teleost, Oreochromis mossambicus (Peters).
The Journal of comparative neurology 1993;327(1):141-50.